Base de dados : MEDLINE
Pesquisa : B01.050.150.900.493.602.200 [Categoria DeCS]
Referências encontradas : 2165 [refinar]
Mostrando: 1 .. 10   no formato [Detalhado]

página 1 de 217 ir para página                         

  1 / 2165 MEDLINE  
              next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28954371
[Au] Autor:Ajima MNO; Pandey PK; Kumar K; Poojary N
[Ad] Endereço:Department of Fisheries and Aquaculture Technology, Federal University of Technology, Owerri, Nigeria. Electronic address: malajimo@gmail.com.
[Ti] Título:Alteration in DNA structure, molecular responses and Na -K -ATPase activities in the gill of Nile tilapia, Oreochromis niloticus (Linnaeus, 1758) in response to sub-lethal verapamil.
[So] Source:Ecotoxicol Environ Saf;147:809-816, 2018 Jan.
[Is] ISSN:1090-2414
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:The ecotoxicological consequences of residues from pharmaceutical drugs on aquatic biota have necessitated the development of sensitive and reliable techniques to assess the impact of these xenobiotics on aquatic organisms. This study investigated the alteration in DNA structure, molecular responses and the activities of Na -K -ATPase and antioxidant enzymes in the gill of Nile tilapia, Oreochromis niloticus, exposed to long-term effects at the concentrations (0.14, 0.28 and 0.57mgL ) of verapamil in static renewal system for 15, 30, 45 and 60 days. Evaluation of DNA structure, using single cell gel electrophoresis, revealed certain degree of DNA damages in the gill in a time and concentration-dependent relationship. Transcription of mRNA of superoxide dismutase (sod), catalase (cat) and heat shock protein (hsp70) genes in the gill of the fish showed the genes were up-regulated. Na -K -ATPase activity was inhibited in a concentration and time dependent manner. The indices of oxidative stress biomarkers (lipid peroxidation and carbonyl protein) as well as superoxide dismutase, glutathione peroxidase, glutathione-S-transferase were elevated in the treated fish in comparison to the control. Further, the level of reduced glutathione and catalase activity were inhibited at 0.28mgL after day 30. Long-term exposure to sub-lethal concentration of verapamil can cause DNA damages, molecular effects and oxidative stress in O. niloticus. The biomarkers analysed can be used as early warning signals in environmental biomonitoring and assessment of drug contamination in aquatic ecosystem.
[Mh] Termos MeSH primário: Ciclídeos/metabolismo
Dano ao DNA
Brânquias/efeitos dos fármacos
ATPase Trocadora de Sódio-Potássio/metabolismo
Verapamil/toxicidade
Poluentes Químicos da Água/toxicidade
[Mh] Termos MeSH secundário: Animais
Antioxidantes/metabolismo
Biomarcadores/metabolismo
Ciclídeos/genética
Relação Dose-Resposta a Droga
Monitoramento Ambiental/métodos
Brânquias/metabolismo
Estresse Oxidativo/efeitos dos fármacos
Verapamil/metabolismo
Poluentes Químicos da Água/metabolismo
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Antioxidants); 0 (Biomarkers); 0 (Water Pollutants, Chemical); CJ0O37KU29 (Verapamil); EC 3.6.3.9 (Sodium-Potassium-Exchanging ATPase)
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180308
[Lr] Data última revisão:
180308
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170929
[St] Status:MEDLINE


  2 / 2165 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28448987
[Au] Autor:Weitekamp CA; Solomon-Lane TK; Del Valle P; Triki Z; Nugent BM; Hofmann HA
[Ad] Endereço:Department of Integrative Biology, The University of Texas at Austin, Austin, TX, USA.
[Ti] Título:A Role for Oxytocin-Like Receptor in Social Habituation in a Teleost.
[So] Source:Brain Behav Evol;89(3):153-161, 2017.
[Is] ISSN:1421-9743
[Cp] País de publicação:Switzerland
[La] Idioma:eng
[Ab] Resumo:Oxytocin (OT) mediates social habituation in rodent model systems, but its role in mediating this effect in other vertebrates is unknown. We used males of the African cichlid fish, Astatotilapia burtoni, to investigate two aspects of isotocin (IT; an OT homolog) signaling in social habituation. First, we examined the expression of IT receptor 2 (ITR2) as well as two immediate early genes in brain regions implicated in social recognition. Next, we examined IT neuron activity using immunohistochemistry. Patterns of gene expression in homologs of the amygdala and hippocampus implicate IT signaling in these regions in social habituation to a territorial neighbor. In the preoptic area, the expression of the ITR2 subtype and IT neuron activity respond to the presence of a male, independent of familiarity. Our results implicate IT in mediating social habituation in a teleost.
[Mh] Termos MeSH primário: Ciclídeos/genética
Ocitocina/análogos & derivados
[Mh] Termos MeSH secundário: Agressão/fisiologia
Tonsila do Cerebelo
Animais
Comportamento Animal/fisiologia
Encéfalo/metabolismo
Ciclídeos/fisiologia
Feminino
Hibridização In Situ
Masculino
Ocitocina/metabolismo
Ocitocina/fisiologia
Área Pré-Óptica/metabolismo
Receptores de Ocitocina/fisiologia
Comportamento Social
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Receptors, Oxytocin); 50-56-6 (Oxytocin); 550-21-0 (isotocin)
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180305
[Lr] Data última revisão:
180305
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170428
[St] Status:MEDLINE
[do] DOI:10.1159/000464098


  3 / 2165 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:29031585
[Au] Autor:Ilves KL; Torti D; López-Fernández H
[Ad] Endereço:Department of Natural History, Royal Ontario Museum, 100 Queen's Park, Toronto, ON M5S 2C6, Canada; Biology Department, Pace University, 1 Pace Plaza, New York, NY 10038, United States. Electronic address: kilves@pace.edu.
[Ti] Título:Exon-based phylogenomics strengthens the phylogeny of Neotropical cichlids and identifies remaining conflicting clades (Cichliformes: Cichlidae: Cichlinae).
[So] Source:Mol Phylogenet Evol;118:232-243, 2018 Jan.
[Is] ISSN:1095-9513
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:The phenotypic, geographic, and species diversity of cichlid fishes have made them a group of great interest for studying evolutionary processes. Here we present a targeted-exon next-generation sequencing approach for investigating the evolutionary relationships of cichlid fishes (Cichlidae), with focus on the Neotropical subfamily Cichlinae using a set of 923 primarily single-copy exons designed through mining of the Nile tilapia (Oreochromis niloticus) genome. Sequence capture and assembly were robust, leading to a complete dataset of 415 exons for 139 species (147 terminals) that consisted of 128 Neotropical species, six African taxa, and five Indo-Malagasy cichlids. Gene and species trees were calculated using alternative partitioning schemes and reconstruction methods. In general, all methods yielded similar topologies to previously hypothesized relationships within the Cichlinae and clarified several relationships that were previously poorly supported or in conflict. Additional work will be needed to fully resolve all aspects of Cichlinae phylogeny. Overall, this approach yielded a well-resolved phylogeny of Neotropical cichlids that will be of utility for future assessments of the evolutionary and ecological processes within this diverse group of fishes. Furthermore, the general methodology employed here of exon targeting and capture should be applicable to any group of organisms with the availability of a reference genome.
[Mh] Termos MeSH primário: Ciclídeos/classificação
[Mh] Termos MeSH secundário: Animais
Sequência de Bases
Evolução Biológica
Ciclídeos/genética
DNA/química
DNA/isolamento & purificação
DNA/metabolismo
Éxons
Sequenciamento de Nucleotídeos em Larga Escala
Filogenia
Alinhamento de Sequência
Análise de Sequência de DNA
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
9007-49-2 (DNA)
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180220
[Lr] Data última revisão:
180220
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171017
[St] Status:MEDLINE


  4 / 2165 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:29320528
[Au] Autor:Peterson T; Müller GB
[Ad] Endereço:Department of Theoretical Biology, University of Vienna, Wien, Austria.
[Ti] Título:Developmental finite element analysis of cichlid pharyngeal jaws: Quantifying the generation of a key innovation.
[So] Source:PLoS One;13(1):e0189985, 2018.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Advances in imaging and modeling facilitate the calculation of biomechanical forces in biological specimens. These factors play a significant role during ontogenetic development of cichlid pharyngeal jaws, a key innovation responsible for one of the most prolific species diversifications in recent times. MicroCT imaging of radiopaque-stained vertebrate embryos were used to accurately capture the spatial relationships of the pharyngeal jaw apparatus in two cichlid species (Haplochromis elegans and Amatitlania nigrofasciata) for the purpose of creating a time series of developmental stages using finite element models, which can be used to assess the effects of biomechanical forces present in a system at multiple points of its ontogeny. Changes in muscle vector orientations, bite forces, force on the neurocranium where cartilage originates, and stress on upper pharyngeal jaws are analyzed in a comparative context. In addition, microCT scanning revealed the presence of previously unreported cement glands in A. nigrofasciata. The data obtained provide an underrepresented dimension of information on physical forces present in developmental processes and assist in interpreting the role of developmental dynamics in evolution.
[Mh] Termos MeSH primário: Estruturas Animais/anatomia & histologia
Ciclídeos/anatomia & histologia
Estresse Mecânico
[Mh] Termos MeSH secundário: Estruturas Animais/embriologia
Estruturas Animais/crescimento & desenvolvimento
Animais
Evolução Biológica
Região Branquial
Ciclídeos/embriologia
Ciclídeos/crescimento & desenvolvimento
Simulação por Computador
Ingestão de Alimentos/fisiologia
Análise de Elementos Finitos
Mastigação/fisiologia
Modelos Biológicos
Morfogênese
Contração Muscular
Músculos Faríngeos/embriologia
Músculos Faríngeos/crescimento & desenvolvimento
Músculos Faríngeos/fisiologia
Crânio/embriologia
Crânio/crescimento & desenvolvimento
Especificidade da Espécie
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180214
[Lr] Data última revisão:
180214
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180111
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0189985


  5 / 2165 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:29215281
[Au] Autor:Shen G; Huang Y; Dong J; Wang X; Cheng KK; Feng J; Xu J; Ye J
[Ad] Endereço:Department of Electronic Science, Fujian Provincial Key Laboratory of Plasma and Magnetic Resonance, Xiamen University , Xiamen 361005, China.
[Ti] Título:Metabolic Effect of Dietary Taurine Supplementation on Nile Tilapia (Oreochromis nilotictus) Evaluated by NMR-Based Metabolomics.
[So] Source:J Agric Food Chem;66(1):368-377, 2018 Jan 10.
[Is] ISSN:1520-5118
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Taurine is indispensable in aquatic diets that are based solely on plant protein, and it promotes growth of many fish species. However, the physiological and metabolome effects of taurine on fish have not been well described. In this study, H NMR-based metabolomics approaches were applied to investigate the metabolite variations in Nile tilapia (Oreochromis nilotictus) muscle in order to visualize the metabolic trajectory and reveal the possible mechanisms of metabolic effects of dietary taurine supplementation on tilapia growth. After extraction using aqueous and organic solvents, 19 taurine-induced metabolic changes were evaluated in our study. The metabolic changes were characterized by differences in carbohydrate, amino acid, lipid, and nucleotide contents. The results indicate that taurine supplementation could significantly regulate the physiological state of fish and promote growth and development. These results provide a basis for understanding the mechanism of dietary taurine supplementation in fish feeding. H NMR spectroscopy, coupled with multivariate pattern recognition technologies, is an efficient and useful tool to map the fish metabolome and identify metabolic responses to different dietary nutrients in aquaculture.
[Mh] Termos MeSH primário: Ciclídeos/metabolismo
Espectroscopia de Ressonância Magnética/métodos
Metabolômica/métodos
Taurina/metabolismo
[Mh] Termos MeSH secundário: Ração Animal/análise
Animais
Ciclídeos/crescimento & desenvolvimento
Suplementos Nutricionais/análise
Proteínas de Peixes/química
Proteínas de Peixes/metabolismo
Músculo Esquelético/química
Músculo Esquelético/metabolismo
[Pt] Tipo de publicação:EVALUATION STUDIES; JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Fish Proteins); 1EQV5MLY3D (Taurine)
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180205
[Lr] Data última revisão:
180205
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171208
[St] Status:MEDLINE
[do] DOI:10.1021/acs.jafc.7b03182


  6 / 2165 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28464822
[Au] Autor:Conte MA; Gammerdinger WJ; Bartie KL; Penman DJ; Kocher TD
[Ad] Endereço:Department of Biology, University of Maryland, 20742, College Park, MD, USA.
[Ti] Título:A high quality assembly of the Nile Tilapia (Oreochromis niloticus) genome reveals the structure of two sex determination regions.
[So] Source:BMC Genomics;18(1):341, 2017 05 02.
[Is] ISSN:1471-2164
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Tilapias are the second most farmed fishes in the world and a sustainable source of food. Like many other fish, tilapias are sexually dimorphic and sex is a commercially important trait in these fish. In this study, we developed a significantly improved assembly of the tilapia genome using the latest genome sequencing methods and show how it improves the characterization of two sex determination regions in two tilapia species. RESULTS: A homozygous clonal XX female Nile tilapia (Oreochromis niloticus) was sequenced to 44X coverage using Pacific Biosciences (PacBio) SMRT sequencing. Dozens of candidate de novo assemblies were generated and an optimal assembly (contig NG50 of 3.3Mbp) was selected using principal component analysis of likelihood scores calculated from several paired-end sequencing libraries. Comparison of the new assembly to the previous O. niloticus genome assembly reveals that recently duplicated portions of the genome are now well represented. The overall number of genes in the new assembly increased by 27.3%, including a 67% increase in pseudogenes. The new tilapia genome assembly correctly represents two recent vasa gene duplication events that have been verified with BAC sequencing. At total of 146Mbp of additional transposable element sequence are now assembled, a large proportion of which are recent insertions. Large centromeric satellite repeats are assembled and annotated in cichlid fish for the first time. Finally, the new assembly identifies the long-range structure of both a ~9Mbp XY sex determination region on LG1 in O. niloticus, and a ~50Mbp WZ sex determination region on LG3 in the related species O. aureus. CONCLUSIONS: This study highlights the use of long read sequencing to correctly assemble recent duplications and to characterize repeat-filled regions of the genome. The study serves as an example of the need for high quality genome assemblies and provides a framework for identifying sex determining genes in tilapia and related fish species.
[Mh] Termos MeSH primário: Ciclídeos/genética
Genômica
Processos de Determinação Sexual/genética
[Mh] Termos MeSH secundário: Animais
Loci Gênicos/genética
Anotação de Sequência Molecular
Sequências Repetitivas de Ácido Nucleico/genética
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, N.I.H., EXTRAMURAL; RESEARCH SUPPORT, U.S. GOV'T, NON-P.H.S.
[Em] Mês de entrada:1712
[Cu] Atualização por classe:180104
[Lr] Data última revisão:
180104
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170504
[St] Status:MEDLINE
[do] DOI:10.1186/s12864-017-3723-5


  7 / 2165 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:27770466
[Au] Autor:Wright DS; Demandt N; Alkema JT; Seehausen O; Groothuis TG; Maan ME
[Ad] Endereço:Groningen Institute for Evolutionary Life Sciences (GELIFES), University of Groningen, Groningen, The Netherlands.
[Ti] Título:Developmental effects of visual environment on species-assortative mating preferences in Lake Victoria cichlid fish.
[So] Source:J Evol Biol;30(2):289-299, 2017 Feb.
[Is] ISSN:1420-9101
[Cp] País de publicação:Switzerland
[La] Idioma:eng
[Ab] Resumo:Local adaptation can be a potent force in speciation, with environmental heterogeneity leading to niche specialization and population divergence. However, local adaption often requires nonrandom mating to generate reproductive isolation. Population divergence in sensory properties can be particularly consequential in speciation, affecting both ecological adaptation and sexual communication. Pundamilia pundamila and Pundamilia nyererei are two closely related African cichlid species that differ in male coloration, blue vs. red. They co-occur at rocky islands in southern Lake Victoria, but inhabit different depth ranges with different light environments. The species differ in colour vision properties, and females exert species-specific preferences for blue vs. red males. Here, we investigated the mechanistic link between colour vision and preference, which could provide a rapid route to reproductive isolation. We tested the behavioural components of this link by experimentally manipulating colour perception - we raised both species and their hybrids under light conditions mimicking shallow and deep habitats - and tested female preference for blue and red males under both conditions. We found that rearing light significantly affected female preference: shallow-reared females responded more strongly to P. pundamilia males and deep-reared females favoured P. nyererei males - implying that visual development causally affects mate choice. These results are consistent with sensory drive predictions, suggesting that the visual environment is key to behavioural isolation of these species. However, the observed plasticity could also make the species barrier vulnerable to environmental change: species-assortative preferences were weaker in females that were reared in the other species' light condition.
[Mh] Termos MeSH primário: Ciclídeos
Reprodução
Isolamento Reprodutivo
[Mh] Termos MeSH secundário: Animais
Feminino
Lagos
Masculino
Especificidade da Espécie
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1712
[Cu] Atualização por classe:171228
[Lr] Data última revisão:
171228
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161023
[St] Status:MEDLINE
[do] DOI:10.1111/jeb.13001


  8 / 2165 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:29185851
[Au] Autor:Borowiec BG; O'Connor CM; Goodick K; Scott GR; Balshine S
[Ti] Título:The Preference for Social Affiliation Renders Fish Willing to Accept Lower O Levels.
[So] Source:Physiol Biochem Zool;91(1):716-724, 2018 Jan/Feb.
[Is] ISSN:1537-5293
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Animals are bombarded with information about their environment and must select and interpret the relevant cues to make behavioral adjustments critical to survival. How animals integrate and balance the many signals they receive about their environment is rarely assessed. We investigated how signals from the social and physical environment interact to influence environmental preferences in the endemic Tanganyikan cichlid Neolamprologus pulcher. Specifically, we explored how fish respond to the physiological challenge of declining O levels in light of embedded social preferences using a modified shuttle box apparatus to test O preferences. In the presence of a conspecific, the average (preferred) partial pressure of oxygen (Po ) and minimum Po experienced were significantly lower ([Formula: see text] and [Formula: see text] kPa, respectively) than in trials without a conspecific ([Formula: see text] and [Formula: see text] kPa, respectively). Fish with conspecifics also spent more time in the low Po zone of the shuttle box and moved between the high and low Po zones less frequently. Hence, O preferences were modified, and fish willingly remained in an area of continuously declining O availability to associate with a conspecific. The O preferences of an individual during social trials correlated with its excess postexercise O consumption following an exhaustive chase but not with its aerobic scope, routine O consumption rate, or body mass. These results suggest that some aspects of respiratory and metabolic physiology (such as the propensity to use anaerobic metabolism) but not others (such as O transport capacity) underpin some variation in social behavior under environmental stress.
[Mh] Termos MeSH primário: Comportamento Animal/fisiologia
Ciclídeos/fisiologia
Oxigênio/química
Comportamento Social
Água/química
[Mh] Termos MeSH secundário: Animais
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
059QF0KO0R (Water); S88TT14065 (Oxygen)
[Em] Mês de entrada:1712
[Cu] Atualização por classe:171215
[Lr] Data última revisão:
171215
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171130
[St] Status:MEDLINE
[do] DOI:10.1086/695566


  9 / 2165 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:29173066
[Au] Autor:Caxico Vieira CAS; Vieira JS; Bastos MS; Zancanela V; Barbosa LT; Gasparino E; Del Vesco AP
[Ad] Endereço:a Animal Science Department , Federal University of Sergipe , São Cristñvão , Brazil.
[Ti] Título:Expression of genes related to antioxidant activity in Nile tilapia kept under salinity stress and fed diets containing different levels of vitamin C.
[So] Source:J Toxicol Environ Health A;81(1-3):20-30, 2018.
[Is] ISSN:1528-7394
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:The aim of this study was to examine whether (1) severe changes in salinity produced increased stress, and (2) vitamin C supplementation might reduce the observed damage in Nile tilapia. The parameters measured included condition factor, survival rate, and gene expression of catalase (CAT), heat shock protein 70 (HSP70), glutathione reductase (GSR), glutathione synthase (GSS), and glutathione peroxidase (GPx). The investigation was conducted with 160 Nile tilapia divided into four treatment groups: freshwater; 7 or 21 parts per thousand (‰) salinity, all fed a basal diet; as well as a fourth treatment group consisting of fish kept at 21‰ salinity fed a diet supplemented with vitamin C (1500 mg/kg). For gene expression analysis, liver samples were collected after 24 h or after 14 d. After 24 h, fish raised in 21‰ salinity and fed with the diet supplemented with vitamin C showed similar GPx expression as the control freshwater group. GSS expression in 21‰ salinity was similar to fish exposed to 7‰ salinity. Nile tilapia exposed to 21‰ salinity without vitamin C supplementation exhibited the highest HSP70 gene expression levels after 24 h. After 14-dtreatment, the lowest survival rate was observed in the 21‰ salinity group. After 14 d, the highest expression of GPx and GSR levels was detected in fish in the 21‰ salinity group that received vitamin C. Data indicate that vitamin C supplementation enhanced the expression of genes related to antioxidant capacity in Nile tilapia exposed to higher salinity, thereby increasing protection against the oxidative effects induced by high water salinity..
[Mh] Termos MeSH primário: Ácido Ascórbico/farmacologia
Ciclídeos/genética
Expressão Gênica
[Mh] Termos MeSH secundário: Ração Animal
Animais
Catalase/genética
Peixes
Glutationa Peroxidase/genética
Glutationa Redutase/genética
Glutationa Sintase/genética
Proteínas de Choque Térmico HSP70/genética
Salinidade
Taxa de Sobrevida
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (HSP70 Heat-Shock Proteins); EC 1.11.1.6 (Catalase); EC 1.11.1.9 (Glutathione Peroxidase); EC 1.8.1.7 (Glutathione Reductase); EC 6.3.2.3 (Glutathione Synthase); PQ6CK8PD0R (Ascorbic Acid)
[Em] Mês de entrada:1712
[Cu] Atualização por classe:171215
[Lr] Data última revisão:
171215
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171128
[St] Status:MEDLINE
[do] DOI:10.1080/15287394.2017.1401968


  10 / 2165 MEDLINE  
              first record previous record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28749047
[Au] Autor:Sun YH; Sun Y; Zhu K; Reid B; Gao X; Draper BW; Zhao M; Mogilner A
[Ad] Endereço:Department of Dermatology and Department of Ophthalmology, University of California, Davis School of Medicine, Sacramento, California.
[Ti] Título:Electric fields accelerate cell polarization and bypass myosin action in motility initiation.
[So] Source:J Cell Physiol;233(3):2378-2385, 2018 Mar.
[Is] ISSN:1097-4652
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Stationary symmetrical fish keratocyte cells break symmetry and become motile spontaneously but slowly. We found that applying electric field (EF) accelerates the polarization by an order of magnitude. While spontaneously polarized cells move persistently for hours, the EF-induced polarity is lost in a majority of cells when the EF is switched off. However, if the EF is applied for a long time and then switched off, the majority of cell move stably. Myosin inhibition abolishes spontaneous polarization, but does not slow down EF-induced polarization, and after the EF is turned off, motility does not stop; however, the cell movements are erratic. Our results suggest that the EF rapidly polarizes the cells, but that resulting polarization becomes stable slowly, and that the EF bypasses the requirement for myosin action in motility initiation.
[Mh] Termos MeSH primário: Escamas de Animais/metabolismo
Movimento Celular
Polaridade Celular
Estimulação Elétrica
Células Epiteliais/metabolismo
Miosinas/metabolismo
[Mh] Termos MeSH secundário: Escamas de Animais/citologia
Animais
Células Cultivadas
Ciclídeos
Fenótipo
Fatores de Tempo
[Pt] Tipo de publicação:JOURNAL ARTICLE; VIDEO-AUDIO MEDIA
[Nm] Nome de substância:
EC 3.6.4.1 (Myosins)
[Em] Mês de entrada:1712
[Cu] Atualização por classe:171212
[Lr] Data última revisão:
171212
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170728
[St] Status:MEDLINE
[do] DOI:10.1002/jcp.26109



página 1 de 217 ir para página                         
   


Refinar a pesquisa
  Base de dados : MEDLINE Formulário avançado   

    Pesquisar no campo  
1  
2
3
 
           



Search engine: iAH v2.6 powered by WWWISIS

BIREME/OPAS/OMS - Centro Latino-Americano e do Caribe de Informação em Ciências da Saúde