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  1 / 2547 MEDLINE  
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[PMID]:28957326
[Au] Autor:Ebel ER; Telis N; Venkataram S; Petrov DA; Enard D
[Ad] Endereço:Department of Biology, Stanford University, Stanford, California, United States of America.
[Ti] Título:High rate of adaptation of mammalian proteins that interact with Plasmodium and related parasites.
[So] Source:PLoS Genet;13(9):e1007023, 2017 Sep.
[Is] ISSN:1553-7404
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Plasmodium parasites, along with their Piroplasm relatives, have caused malaria-like illnesses in terrestrial mammals for millions of years. Several Plasmodium-protective alleles have recently evolved in human populations, but little is known about host adaptation to blood parasites over deeper evolutionary timescales. In this work, we analyze mammalian adaptation in ~500 Plasmodium- or Piroplasm- interacting proteins (PPIPs) manually curated from the scientific literature. We show that (i) PPIPs are enriched for both immune functions and pleiotropy with other pathogens, and (ii) the rate of adaptation across mammals is significantly elevated in PPIPs, compared to carefully matched control proteins. PPIPs with high pathogen pleiotropy show the strongest signatures of adaptation, but this pattern is fully explained by their immune enrichment. Several pieces of evidence suggest that blood parasites specifically have imposed selection on PPIPs. First, even non-immune PPIPs that lack interactions with other pathogens have adapted at twice the rate of matched controls. Second, PPIP adaptation is linked to high expression in the liver, a critical organ in the parasite life cycle. Finally, our detailed investigation of alpha-spectrin, a major red blood cell membrane protein, shows that domains with particularly high rates of adaptation are those known to interact specifically with P. falciparum. Overall, we show that host proteins that interact with Plasmodium and Piroplasm parasites have experienced elevated rates of adaptation across mammals, and provide evidence that some of this adaptation has likely been driven by blood parasites.
[Mh] Termos MeSH primário: Adaptação Fisiológica/genética
Apicomplexa/patogenicidade
Interações Hospedeiro-Parasita/genética
Mamíferos/parasitologia
Plasmodium falciparum/patogenicidade
Espectrina/genética
[Mh] Termos MeSH secundário: Animais
Artiodáctilos/parasitologia
Evolução Molecular
Regulação da Expressão Gênica
Seres Humanos
Primatas/parasitologia
Roedores/parasitologia
Alinhamento de Sequência
Espectrina/metabolismo
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
12634-43-4 (Spectrin)
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171031
[Lr] Data última revisão:
171031
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170929
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pgen.1007023


  2 / 2547 MEDLINE  
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[PMID]:28854247
[Au] Autor:Streicher S; Lutermann H; Bennett NC; Bertelsen MF; Mohammed OB; Manger PR; Scantlebury M; Ismael K; Alagaili AN
[Ad] Endereço:Department of Zoology and Entomology, University of Pretoria, Pretoria, South Africa.
[Ti] Título:Living on the edge: Daily, seasonal and annual body temperature patterns of Arabian oryx in Saudi Arabia.
[So] Source:PLoS One;12(8):e0180269, 2017.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Heterothermy, the ability to allow body temperature (Tb) to fluctuate, has been proposed as an adaptive mechanism that enables large ungulates to cope with the high environmental temperatures and lack of free water experienced in arid environments. By storing heat during the daytime and dissipating it during the night, arid-adapted ungulates may reduce evaporative water loss and conserve water. Adaptive heterothermy in large ungulates should be particularly pronounced in hot environments with severely limited access to free water. In the current study we investigated the effects of environmental temperature (ambient, Ta and soil, Ts) and water stress on the Tb of wild, free-ranging Arabian oryx (Oryx leucoryx) in two different sites in Saudi Arabia, Mahazat as-Sayd (MS) and Uruq Bani Ma'arid (UBM). Using implanted data loggers wet took continuous Tb readings every 10 minutes for an entire calendar year and determined the Tb amplitude as well as the heterothermy index (HI). Both differed significantly between sites but contrary to our expectations they were greater in MS despite its lower environmental temperatures and higher rainfall. This may be partially attributable to a higher activity in an unfamiliar environment for translocated animals in UBM. As expected Tb amplitude and HI were greatest during summer. Only minor sex differences were apparent that may be attributable to sex-specific investment into reproduction (e.g. male-male competition) during rut. Our results suggest that the degree of heterothermy is not only driven by extrinsic factors (e.g. environmental temperatures and water availability), but may also be affected by intrinsic factors (e.g. sex and/or behaviour).
[Mh] Termos MeSH primário: Artiodáctilos/fisiologia
Regulação da Temperatura Corporal
[Mh] Termos MeSH secundário: Animais
Tamanho Corporal
Temperatura Corporal
Clima Desértico
Feminino
Masculino
Arábia Saudita
Estações do Ano
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171013
[Lr] Data última revisão:
171013
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170831
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0180269


  3 / 2547 MEDLINE  
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[PMID]:28753519
[Au] Autor:Eibler D; Seyfried C; Vetter W
[Ad] Endereço:University of Hohenheim, Institute of Food Chemistry, Garbenstr. 28, 70599 Stuttgart, Germany.
[Ti] Título:Enantioselectivity of anteiso-fatty acids in hitherto uninspected sample matrices.
[So] Source:J Chromatogr B Analyt Technol Biomed Life Sci;1061-1062:233-239, 2017 Sep 01.
[Is] ISSN:1873-376X
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:Anteiso-fatty acids (aFAs) are chiral molecules due to a methyl substituent on the antepenultimate carbon of the otherwise straight acyl chain. 12-Methyltetradecanoic acid (a15:0) and 14-methylhexadecanoic acid (a17:0) are the predominant aFAs in nature but their individual contributions e.g. to food lipids are usually low. Enantioselective data has been collected in fish, bovine milk/cheese, and Brussels sprouts. In this study, we determined the enantioselectivity of a15:0 and a17:0 in shea butter, moose and camel milk, two soil samples and mold (collected from contaminated cheese). For this purpose, sample lipids were extracted and containing fatty acids were converted into methyl esters. Methyl esters of aFAs were selectively enriched by hydrogenation, urea complexation and/or RP-HPLC-fractionation. Enantioselective gas chromatography with mass spectrometry operated in the selected ion monitoring mode using a chiral stationary phase consisting of 66% tert.-butyldimethylsilylated ß-cyclodextrin in OV-1701. While a15:0 and a17:0 in moose milk were (S)-enantiopure, all other determined samples contained up to 10% (R)-aFAs. The highest proportions of (R)-enantiomers were detected in the soil samples (ee=80%).
[Mh] Termos MeSH primário: Ácidos Graxos/análise
Ácidos Graxos/química
Cromatografia Gasosa-Espectrometria de Massas/métodos
[Mh] Termos MeSH secundário: Animais
Artiodáctilos
Camelus
Ácidos Graxos/isolamento & purificação
Leite/química
Óleos Vegetais/química
Estereoisomerismo
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Fatty Acids); 0 (Plant Oils)
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170926
[Lr] Data última revisão:
170926
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170729
[St] Status:MEDLINE


  4 / 2547 MEDLINE  
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[PMID]:28727516
[Au] Autor:Hubálek Z; Juricová Z; Straková P; Blazejová H; Betásová L; Rudolf I
[Ad] Endereço:1 Institute of Vertebrate Biology , Academy of Sciences, v.v.i., Brno, Czech Republic .
[Ti] Título:Serological Survey for West Nile Virus in Wild Artiodactyls, Southern Moravia (Czech Republic).
[So] Source:Vector Borne Zoonotic Dis;17(9):654-657, 2017 Sep.
[Is] ISSN:1557-7759
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Antibodies to West Nile virus (WNV) were examined by plaque-reduction neutralization test in the blood sera of 1023 wild artiodactyls: 105 roe deer (Capreolus capreolus), 148 red deer (Cervus elaphus), 287 fallow deer (Dama dama), 71 mouflons (Ovis musimon), and 412 wild boars (Sus scrofa), sampled in South Moravian district of Breclav (Czech Republic) in the years 1990-2008. Neutralizing antibodies were detected in 5.9% of wild ruminants (4.8% roe deer, 4.1% red deer, 6.3% fallow deer, 9.9% mouflons) and 4.1% of wild boars, with titers ranging between 1:20 and 1:320. The results indicate that WNV has circulated in wild artiodactyls at a variable frequency during the years in the area.
[Mh] Termos MeSH primário: Animais Selvagens
Anticorpos Antivirais/sangue
Artiodáctilos
Febre do Nilo Ocidental/veterinária
[Mh] Termos MeSH secundário: Animais
Anticorpos Neutralizantes/sangue
República Tcheca/epidemiologia
Feminino
Masculino
Estudos Soroepidemiológicos
Fatores de Tempo
Febre do Nilo Ocidental/sangue
Febre do Nilo Ocidental/epidemiologia
Febre do Nilo Ocidental/virologia
Vírus do Nilo Ocidental/isolamento & purificação
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Antibodies, Neutralizing); 0 (Antibodies, Viral)
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170926
[Lr] Data última revisão:
170926
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170721
[St] Status:MEDLINE
[do] DOI:10.1089/vbz.2017.2109


  5 / 2547 MEDLINE  
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[PMID]:28708854
[Au] Autor:Mpakairi KS; Ndaimani H; Tagwireyi P; Gara TW; Zvidzai M; Madhlamoto D
[Ad] Endereço:Department of Geography and Environmental Science, University of Zimbabwe, Harare, Zimbabwe.
[Ti] Título:Missing in action: Species competition is a neglected predictor variable in species distribution modelling.
[So] Source:PLoS One;12(7):e0181088, 2017.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:The central role of species competition in shaping community structure in ecosystems is well appreciated amongst ecologists. However species competition is a consistently missing variable in Species Distribution Modelling (SDM). This study presents results of our attempt to incorporate species competition in SDMs. We used a suit of predictor variables including Soil Adjusted Vegetation Index (SAVI), as well as distance from roads, settlements and water, fire frequency and distance from the nearest herbivore sighting (of selected herbivores) to model individual habitat preferences of five grazer species (buffalo, warthog, waterbuck, wildebeest and zebra) with the Ensemble SDM algorithm for Gonarezhou National Park, Zimbabwe. Our results showed that distance from the nearest animal sighting (a proxy for competition among grazers) was the best predictor of the potential distribution of buffalo, wildebeest and zebra but the second best predictor for warthog and waterbuck. Our findings provide evidence to that competition is an important predictor of grazer species' potential distribution. These findings suggest that species distribution modelling that neglects species competition may be inadequate in explaining the potential distribution of species. Therefore our findings encourage the inclusion of competition in SDM as well as potentially igniting discussions that may lead to improving the predictive power of future SDM efforts.
[Mh] Termos MeSH primário: Artiodáctilos/fisiologia
Equidae/fisiologia
Modelos Biológicos
[Mh] Termos MeSH secundário: Algoritmos
Animais
Ecossistema
Dinâmica Populacional
Zimbábue
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170927
[Lr] Data última revisão:
170927
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170715
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0181088


  6 / 2547 MEDLINE  
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[PMID]:28640276
[Au] Autor:Watson T
[Ti] Título:Teeth tell tale of hippo's quick spread across Africa.
[So] Source:Nature;546(7659):462, 2017 06 20.
[Is] ISSN:1476-4687
[Cp] País de publicação:England
[La] Idioma:eng
[Mh] Termos MeSH primário: Migração Animal
Artiodáctilos/fisiologia
Dieta/veterinária
Fósseis
Poaceae
Dente/anatomia & histologia
[Mh] Termos MeSH secundário: África
Animais
Seres Humanos
Modelos Biológicos
[Pt] Tipo de publicação:NEWS
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171019
[Lr] Data última revisão:
171019
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170623
[St] Status:MEDLINE
[do] DOI:10.1038/nature.2017.22168


  7 / 2547 MEDLINE  
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Langoni, Hélio
Biondo, Alexander Welker
Texto completo SciELO Brasil
[PMID]:28562764
[Au] Autor:Ullmann LS; Gravinatti ML; Yamatogi RS; Santos LCD; Moraes W; Cubas ZS; Camossi LG; Barros IR; Langoni H; Vieira RFDC; Biondo AW
[Ad] Endereço:Departamento de Microbiologia e Imunologia, Universidade Estadual Paulista, Botucatu, SP, Brasil.
[Ti] Título:Serosurvey of anti- Leptospira sp. and anti- Toxoplasma gondii antibodies in capybaras and collared and white-lipped peccaries.
[So] Source:Rev Soc Bras Med Trop;50(2):248-250, 2017 Mar-Apr.
[Is] ISSN:1678-9849
[Cp] País de publicação:Brazil
[La] Idioma:eng
[Ab] Resumo:INTRODUCTION:: Brazilian native species are reemerging as increasingly free-ranging populations. METHODS:: Sera from 31 capybaras (Hydrochoerus hydrochaeris) and 28 peccaries (Pecari tajacu and Tayassu pecari) were tested for anti-Leptospira and anti-Toxoplasma gondii antibodies using microscopic seroagglutination test. RESULTS:: Nineteen percent of free-ranging and 10.0% of captive capybaras, along with 31.8% of collared peccaries, were seropositive for T. gondii. None was seropositive for Leptospira sp. CONCLUSIONS:: The present findings indicated low risk of disease, particularly among capybaras and white-lipped peccaries; however, active surveillance programs are important for monitoring wildlife health and public health once they are in public parks around cities.
[Mh] Termos MeSH primário: Leptospirose/veterinária
Toxoplasmose Animal/epidemiologia
[Mh] Termos MeSH secundário: Testes de Aglutinação
Animais
Animais Selvagens
Anticorpos Antibacterianos/sangue
Anticorpos Antiprotozoários/sangue
Artiodáctilos/microbiologia
Artiodáctilos/parasitologia
Brasil/epidemiologia
Leptospira/imunologia
Leptospirose/diagnóstico
Leptospirose/epidemiologia
Prevalência
Roedores/microbiologia
Roedores/parasitologia
Toxoplasma/imunologia
Toxoplasmose Animal/diagnóstico
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Antibodies, Bacterial); 0 (Antibodies, Protozoan)
[Em] Mês de entrada:1707
[Cu] Atualização por classe:170705
[Lr] Data última revisão:
170705
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170601
[St] Status:MEDLINE


  8 / 2547 MEDLINE  
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[PMID]:28363818
[Au] Autor:Perry T; van Loenen AL; Heiniger H; Lee C; Gongora J; Cooper A; Mitchell KJ
[Ad] Endereço:Australian Centre for Ancient DNA, School of Biological Sciences, University of Adelaide, Australia. Electronic address: tahlia.perry@adelaide.edu.au.
[Ti] Título:Ancient DNA analysis of the extinct North American flat-headed peccary (Platygonus compressus).
[So] Source:Mol Phylogenet Evol;112:258-267, 2017 Jul.
[Is] ISSN:1095-9513
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:The geographical range of extant peccaries extends from the southwestern United States through Central America and into northern Argentina. However, from the Miocene until the Pleistocene now-extinct peccary species inhabited the entirety of North America. Relationships among the living and extinct species have long been contentious. Similarly, how and when peccaries moved from North to South America is unclear. The North American flat-headed peccary (Platygonus compressus) became extinct at the end of the Pleistocene and is one of the most abundant subfossil taxa found in North America, yet despite this extensive fossil record its phylogenetic position has not been resolved. This study is the first to present DNA data from the flat-headed peccary and full mitochondrial genome sequences of all the extant peccary species. We performed a molecular phylogenetic analysis to determine the relationships among ancient and extant peccary species. Our results suggested that the flat-headed peccary is sister-taxon to a clade comprising the extant peccary species. Divergence date estimates from our molecular dating analyses suggest that if extant peccary diversification occurred in South America then their common ancestor must have dispersed from North America to South America well before the establishment of the Isthmus of Panama. We also investigated the genetic diversity of the flat-headed peccary by performing a preliminary population study on specimens from Sheriden Cave, Ohio. Flat-headed peccaries from Sheriden Cave appear to be genetically diverse and show no signature of population decline prior to extinction. Including additional extinct Pleistocene peccary species in future phylogenetic analyses will further clarify peccary evolution.
[Mh] Termos MeSH primário: Artiodáctilos/genética
DNA Antigo/análise
Extinção Biológica
[Mh] Termos MeSH secundário: Animais
Teorema de Bayes
DNA Mitocondrial/genética
Evolução Molecular
Fósseis
Variação Genética
Genoma Mitocondrial
Geografia
Haplótipos/genética
América do Norte
Filogenia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (DNA, Ancient); 0 (DNA, Mitochondrial)
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171030
[Lr] Data última revisão:
171030
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170402
[St] Status:MEDLINE


  9 / 2547 MEDLINE  
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[PMID]:28363073
[Au] Autor:Franklinos LH; Masters N; Feltrer Y; Pocknell A; Bolt DM; Dakin S; Berry K; Molenaar FM
[Ti] Título:THE MANAGEMENT OF AN ORAL ANAPLASTIC SARCOMA IN A PYGMY HIPPOPOTAMUS (CHOEROPSIS LIBERIENSIS) USING INTRALESIONAL CHEMOTHERAPY.
[So] Source:J Zoo Wildl Med;48(1):260-264, 2017 Mar.
[Is] ISSN:1042-7260
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:An adult female captive pygmy hippopotamus (Choeropsis liberiensis) was diagnosed with an oral anaplastic sarcoma. The tumor was surgically debulked and intralesional chemotherapy with mitomycin C (0.4 mg/cm of tumor) and cisplatin (1 mg/cm of tumor) was administered. Chemotherapeutic treatment proved difficult due to the risks of repeated anesthetics and unknown drug efficacies. Marked proliferation of the mass was observed during estrus, and chemotherapy was repeated as an experimental treatment to slow tumor progression in order for the animal to remain in the species breeding program. Tumor proliferation was detected during the first trimester of pregnancy; however, in the lactation period, the mass became quiescent. No adverse reactions to chemotherapeutic drugs were observed and the animal continues to be monitored for tumor progression. This is the first report of an anaplastic sarcoma and of chemotherapy use in a pygmy hippopotamus and it highlights logistical considerations for treating neoplasia in this species.
[Mh] Termos MeSH primário: Antineoplásicos/uso terapêutico
Artiodáctilos
Cisplatino/uso terapêutico
Mitomicina/uso terapêutico
Neoplasias Bucais/veterinária
Sarcoma/veterinária
[Mh] Termos MeSH secundário: Animais
Antineoplásicos/administração & dosagem
Cisplatino/administração & dosagem
Ciclo Estral
Feminino
Mitomicina/administração & dosagem
Neoplasias Bucais/tratamento farmacológico
Gravidez
Sarcoma/tratamento farmacológico
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Antineoplastic Agents); 50SG953SK6 (Mitomycin); Q20Q21Q62J (Cisplatin)
[Em] Mês de entrada:1706
[Cu] Atualização por classe:170619
[Lr] Data última revisão:
170619
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170401
[St] Status:MEDLINE
[do] DOI:10.1638/2016-0015.1


  10 / 2547 MEDLINE  
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[PMID]:28268153
[Au] Autor:Dubost G
[Ad] Endereço:Muséum national d'histoire naturelle, EGB-UMR 7204 MNHN-CNRS-UPMC, Ménagerie du Jardin des plantes, 57, rue Cuvier, 75231 Paris cedex 05, France. Electronic address: gerard.dubost@mnhn.fr.
[Ti] Título:Convergence characteristics between a rodent, the South American lowland paca, and a ruminant, the African water chevrotain: An exemplary case study.
[So] Source:C R Biol;340(3):178-187, 2017 Mar.
[Is] ISSN:1768-3238
[Cp] País de publicação:France
[La] Idioma:eng
[Ab] Resumo:The level of convergence between a rodent, the South American lowland paca Cuniculus paca, and a ruminant, the African water chevrotain Hyemoschus aquaticus, is analysed using 231 characteristics belonging to different biological sectors. A convergence index is established based on the degree of rarity of each characteristic in each species compared to other members of its zoological group. Although the divergent characteristics are as numerous as the convergent ones, the two species are globally similar. Convergent characteristics occur in all biological categories, but their rate varies a great deal among them. From internal anatomy and osteology, through behaviour and ecology to the external appearance of the body, convergent characteristics are all the more frequent since the biological category is directly implicated in the adaptation of animals to their external environment (lowland rainforest). However, only the individuals' characteristics are concerned and not those of their population or social organisation. This could be due to differences between the communities of terrestrial mammals to which they belong.
[Mh] Termos MeSH primário: Artiodáctilos/fisiologia
Cuniculidae/fisiologia
[Mh] Termos MeSH secundário: Animais
Ecologia
[Pt] Tipo de publicação:COMPARATIVE STUDY; JOURNAL ARTICLE
[Em] Mês de entrada:1706
[Cu] Atualização por classe:170606
[Lr] Data última revisão:
170606
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170308
[St] Status:MEDLINE



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