Base de dados : MEDLINE
Pesquisa : B01.050.150.900.649.313.875.865 [Categoria DeCS]
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[PMID]:29256430
[Au] Autor:Stimmelmayr R; Rotstein D; Seguel M; Gottdenker N
[Ad] Endereço:North Slope Borough Department of Wildlife Management, Barrow, Alaska 99723, USA.
[Ti] Título:Hepatic lipomas and myelolipomas in subsistence-harvested bowhead whales Balaena mysticetus, Alaska (USA): a case review 1980-2016.
[So] Source:Dis Aquat Organ;127(1):71-74, 2017 Dec 19.
[Is] ISSN:0177-5103
[Cp] País de publicação:Germany
[La] Idioma:eng
[Ab] Resumo:We describe a case series of benign hepatic fatty tumors in 10 subsistence-harvested bowhead whales. Microscopic features included lipomatous and myelolipomatous masses. Extensive atrophy and/or destruction of hepatic parenchyma was not observed. No other significant disease was present except in an animal with unrelated chronic pleuritis. Based on our longitudinal case series (1980-2016) which identified 1-2 hepatic lipomas and myelolipomas in landed whales annually at Barrow, Alaska (USA), since 2012, hepatic lipomas and myelolipomas are occasionally seen in hunter-harvested bowhead whales. A conservative estimate for the percentage of bowhead whales with hepatic fatty tumors in landed whales in Barrow from 2012 to 2016 was 6% (7/111). The pathogenesis and exact cell origin of these benign fatty tumors in bowhead whales is undetermined. Assessment of further cases is warranted to better define the tissue distribution and pathogenesis of these tumors in bowhead whale liver.
[Mh] Termos MeSH primário: Lipoma/veterinária
Neoplasias Hepáticas/veterinária
Mielolipoma/veterinária
Baleias
[Mh] Termos MeSH secundário: Alaska
Animais
Feminino
Lipoma/epidemiologia
Lipoma/patologia
Neoplasias Hepáticas/epidemiologia
Masculino
Mielolipoma/epidemiologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180305
[Lr] Data última revisão:
180305
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171220
[St] Status:MEDLINE
[do] DOI:10.3354/dao03186


  2 / 2808 MEDLINE  
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[PMID]:29020021
[Au] Autor:Joyce TW; Durban JW; Claridge DE; Dunn CA; Fearnbach H; Parsons KM; Andrews RD; Ballance LT
[Ad] Endereço:Scripps Institution of Oceanography, University of California San Diego, La Jolla, California, United States of America.
[Ti] Título:Physiological, morphological, and ecological tradeoffs influence vertical habitat use of deep-diving toothed-whales in the Bahamas.
[So] Source:PLoS One;12(10):e0185113, 2017.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Dive capacity among toothed whales (suborder: Odontoceti) has been shown to generally increase with body mass in a relationship closely linked to the allometric scaling of metabolic rates. However, two odontocete species tagged in this study, the Blainville's beaked whale Mesoplodon densirostris and the Cuvier's beaked whale Ziphius cavirostris, confounded expectations of a simple allometric relationship, with exceptionally long (mean: 46.1 min & 65.4 min) and deep dives (mean: 1129 m & 1179 m), and comparatively small body masses (med.: 842.9 kg & 1556.7 kg). These two species also exhibited exceptionally long recovery periods between successive deep dives, or inter-deep-dive intervals (M. densirostris: med. 62 min; Z. cavirostris: med. 68 min). We examined competing hypotheses to explain observed patterns of vertical habitat use based on body mass, oxygen binding protein concentrations, and inter-deep-dive intervals in an assemblage of five sympatric toothed whales species in the Bahamas. Hypotheses were evaluated using dive data from satellite tags attached to the two beaked whales (M. densirostris, n = 12; Z. cavirostris, n = 7), as well as melon-headed whales Peponocephala electra (n = 13), short-finned pilot whales Globicephala macrorhynchus (n = 15), and sperm whales Physeter macrocephalus (n = 27). Body mass and myoglobin concentration together explained only 36% of the variance in maximum dive durations. The inclusion of inter-deep-dive intervals, substantially improved model fits (R2 = 0.92). This finding supported a hypothesis that beaked whales extend foraging dives by exceeding aerobic dive limits, with the extension of inter-deep-dive intervals corresponding to metabolism of accumulated lactic acid. This inference points to intriguing tradeoffs between body size, access to prey in different depth strata, and time allocation within dive cycles. These tradeoffs and resulting differences in habitat use have important implications for spatial distribution patterns, and relative vulnerabilities to anthropogenic impacts.
[Mh] Termos MeSH primário: Mergulho/fisiologia
Ecossistema
Baleias/anatomia & histologia
Baleias/fisiologia
[Mh] Termos MeSH secundário: Animais
Bahamas
Peso Corporal
Ritmo Circadiano/fisiologia
Comportamento Alimentar
Feminino
Análise dos Mínimos Quadrados
Masculino
Modelos Teóricos
Mioglobina/metabolismo
Filogenia
Comunicações Via Satélite
Especificidade da Espécie
Fatores de Tempo
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Myoglobin)
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171031
[Lr] Data última revisão:
171031
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171012
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0185113


  3 / 2808 MEDLINE  
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[PMID]:28898601
[Au] Autor:DeWoody JA; Fernandez NB; Brüniche-Olsen A; Antonides JD; Doyle JM; San Miguel P; Westerman R; Vertyankin VV; Godard-Codding CAJ; Bickham JW
[Ti] Título:Characterization of the Gray Whale Eschrichtius robustus Genome and a Genotyping Array Based on Single-Nucleotide Polymorphisms in Candidate Genes.
[So] Source:Biol Bull;232(3):186-197, 2017 Jun.
[Is] ISSN:1939-8697
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Genetic and genomic approaches have much to offer in terms of ecology, evolution, and conservation. To better understand the biology of the gray whale Eschrichtius robustus (Lilljeborg, 1861), we sequenced the genome and produced an assembly that contains ∼95% of the genes known to be highly conserved among eukaryotes. From this assembly, we annotated 22,711 genes and identified 2,057,254 single-nucleotide polymorphisms (SNPs). Using this assembly, we generated a curated list of candidate genes potentially subject to strong natural selection, including genes associated with osmoregulation, oxygen binding and delivery, and other aspects of marine life. From these candidate genes, we queried 92 autosomal protein-coding markers with a panel of 96 SNPs that also included 2 sexing and 2 mitochondrial markers. Genotyping error rates, calculated across loci and across 69 intentional replicate samples, were low (0.021%), and observed heterozygosity was 0.33 averaged over all autosomal markers. This level of variability provides substantial discriminatory power across loci (mean probability of identity of 1.6 × 10 and mean probability of exclusion >0.999 with neither parent known), indicating that these markers provide a powerful means to assess parentage and relatedness in gray whales. We found 29 unique multilocus genotypes represented among our 36 biopsies (indicating that we inadvertently sampled 7 whales twice). In total, we compiled an individual data set of 28 western gray whales (WGSs) and 1 presumptive eastern gray whale (EGW). The lone EGW we sampled was no more or less related to the WGWs than expected by chance alone. The gray whale genomes reported here will enable comparative studies of natural selection in cetaceans, and the SNP markers should be highly informative for future studies of gray whale evolution, population structure, demography, and relatedness.
[Mh] Termos MeSH primário: Genoma/genética
Baleias/genética
[Mh] Termos MeSH secundário: Animais
Variação Genética
Genética Populacional
Genótipo
Polimorfismo de Nucleotídeo Único/genética
Especificidade da Espécie
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171027
[Lr] Data última revisão:
171027
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170913
[St] Status:MEDLINE
[do] DOI:10.1086/693483


  4 / 2808 MEDLINE  
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Caramelli, Paulo
Texto completo
[PMID]:28871062
[Au] Autor:de Souza LC; Teixeira AL; de Oliveira GNM; Caramelli P; Cardoso F
[Ad] Endereço:From Programa de Pós-Graduação em Neurociências (L.C.d.S., A.L.T., P.C., F.C.), Departamento de Clínica Médica, Faculdade de Medicina (L.C.d.S., A.L.T., P.C., F.C.), and Serviço de Neurologia, Hospital das Clínicas (L.C.d.S., A.L.T., P.C., F.C.), Universidade Federal de Minas Gerais (UFMG), Belo Hor
[Ti] Título:A critique of phrenology in .
[So] Source:Neurology;89(10):1087-1090, 2017 Sep 05.
[Is] ISSN:1526-632X
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Phrenology has a fascinating, although controversial, place in the history of localizationism of brain and mental functions. The 2 main proponents of phrenology were 2 German-speaking doctors, Joseph Gall (1758-1828) and Johann Spurzheim (1776-1832). According to their theory, a careful examination of skull morphology could disclose personality characters. Phrenology was initially restricted to medical circles and then diffused outside scientific societies, reaching nonscientific audiences in Europe and North America. Phrenology deeply penetrated popular culture in the 19th century and its tenets can be observed in British and American literature. Here we analyze the presence of phrenologic concepts in , by Herman Melville (1819-1891), one of the most prominent American writers. In his masterpiece, he demonstrates that he was familiarized with Gall and Spurzheim's writings, but referred to their theory as "semi-science" and "a passing fable." Of note, Melville's fine irony against phrenology is present in his attempt to perform a phrenologic and physiognomic examination of The Whale. Thus, illustrates the diffusion of phrenology in Western culture, but may also reflect Melville's skepticism and criticism toward its main precepts.
[Mh] Termos MeSH primário: Medicina na Literatura
Frenologia/história
[Mh] Termos MeSH secundário: Animais
História do Século XIX
Seres Humanos
América do Norte
Crânio/anatomia & histologia
Baleias/anatomia & histologia
[Pt] Tipo de publicação:BIOGRAPHY; HISTORICAL ARTICLE; JOURNAL ARTICLE
[Ps] Nome de pessoa como assunto:Melville H
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170908
[Lr] Data última revisão:
170908
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:170906
[St] Status:MEDLINE
[do] DOI:10.1212/WNL.0000000000004335


  5 / 2808 MEDLINE  
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[PMID]:28827838
[Au] Autor:Rockwood RC; Calambokidis J; Jahncke J
[Ad] Endereço:Point Blue Conservation Science, Petaluma, California, United States of America.
[Ti] Título:High mortality of blue, humpback and fin whales from modeling of vessel collisions on the U.S. West Coast suggests population impacts and insufficient protection.
[So] Source:PLoS One;12(8):e0183052, 2017.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Mortality from collisions with vessels is one of the main human causes of death for large whales. Ship strikes are rarely witnessed and the distribution of strike risk and estimates of mortality remain uncertain at best. We estimated ship strike mortality for blue humpback and fin whales in U.S. West Coast waters using a novel application of a naval encounter model. Mortality estimates from the model were far higher than current minimum estimates derived from stranding records and are closer to extrapolations adjusted for detection probabilities of dead whales. Our most conservative model estimated mortality to be 7.8x, 2.0x and 2.7x the U.S. recommended limit for blue, humpback and fin whales, respectively, suggesting that death from vessel collisions may be a significant impediment to population growth and recovery. Comparing across the study area, the majority of strike mortality occurs in waters off California, from Bodega Bay south and tends to be concentrated in a band approximately 24 Nm (44.5 km) offshore and in designated shipping lanes leading to and from major ports. While some mortality risk exists across nearly all West Coast waters, 74%, 82% and 65% of blue, humpback and fin whale mortality, respectively, occurs in just 10% of the study area, suggesting conservation efforts can be very effective if focused in these waters. Risk is highest in the shipping lanes off San Francisco and Long Beach, but only a fraction of total estimated mortality occurs in these proportionally small areas, making any conservation efforts exclusively within these areas insufficient to address overall strike mortality. We recommend combining shipping lane modifications and re-locations, ship speed reductions and creation of 'Areas to be Avoided' by vessels in ecologically important locations to address this significant source of whale mortality.
[Mh] Termos MeSH primário: Navios
Baleias/classificação
[Mh] Termos MeSH secundário: Animais
Mortalidade
Densidade Demográfica
Risco
Especificidade da Espécie
Estados Unidos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171013
[Lr] Data última revisão:
171013
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170823
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0183052


  6 / 2808 MEDLINE  
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[PMID]:28682334
[Au] Autor:Clapham PJ
[Ad] Endereço:Alaska Fisheries Science Center, Seattle, Washington, USA.
[Ti] Título:Whaling permits: Japan disregards whaling review again.
[So] Source:Nature;547(7661):32, 2017 07 05.
[Is] ISSN:1476-4687
[Cp] País de publicação:England
[La] Idioma:eng
[Mh] Termos MeSH primário: Pesqueiros
Baleias
[Mh] Termos MeSH secundário: Animais
Japão
[Pt] Tipo de publicação:JOURNAL ARTICLE; COMMENT
[Em] Mês de entrada:1708
[Cu] Atualização por classe:171027
[Lr] Data última revisão:
171027
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170707
[St] Status:MEDLINE
[do] DOI:10.1038/547032b


  7 / 2808 MEDLINE  
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[PMID]:28617462
[Au] Autor:Managi S; Wakamatsu M
[Ad] Endereço:Kyushu University, Fukuoka, Japan.
[Ti] Título:Conservation: Pay countries to stop whaling.
[So] Source:Nature;546(7658):352, 2017 06 14.
[Is] ISSN:1476-4687
[Cp] País de publicação:England
[La] Idioma:eng
[Mh] Termos MeSH primário: Conservação dos Recursos Naturais/economia
Conservação dos Recursos Naturais/métodos
Baleias
[Mh] Termos MeSH secundário: Animais
Austrália
Japão
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171012
[Lr] Data última revisão:
171012
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170616
[St] Status:MEDLINE
[do] DOI:10.1038/546352c


  8 / 2808 MEDLINE  
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[PMID]:28542468
[Au] Autor:Peredo CM; Pyenson ND; Uhen MD; Marshall CD
[Ad] Endereço:Department of Environmental Science and Policy, George Mason University, Fairfax, VA, United States of America.
[Ti] Título:Alveoli, teeth, and tooth loss: Understanding the homology of internal mandibular structures in mysticete cetaceans.
[So] Source:PLoS One;12(5):e0178243, 2017.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:The evolution of filter feeding in baleen whales (Mysticeti) facilitated a wide range of ecological diversity and extreme gigantism. The innovation of filter feeding evolved in a shift from a mineralized upper and lower dentition in stem mysticetes to keratinous baleen plates that hang only from the roof of the mouth in extant species, which are all edentulous as adults. While all extant mysticetes are born with a mandible lacking a specialized feeding structure (i.e., baleen), the bony surface retains small foramina with elongated sulci that often merge together in what has been termed the alveolar gutter. Because mysticete embryos develop tooth buds that resorb in utero, these foramina have been interpreted as homologous to tooth alveoli in other mammals. Here, we test this homology by creating 3D models of the internal mandibular morphology from terrestrial artiodactyls and fossil and extant cetaceans, including stem cetaceans, odontocetes and mysticetes. We demonstrate that dorsal foramina on the mandible communicate with the mandibular canal via smaller canals, which we explain within the context of known mechanical models of bone resorption. We suggest that these dorsal foramina represent distinct branches of the inferior alveolar nerve (or artery), rather than alveoli homologous with those of other mammals. As a functional explanation, we propose that these branches provide sensation to the dorsal margin of the mandible to facilitate placement and occlusion of the baleen plates during filer feeding.
[Mh] Termos MeSH primário: Mandíbula/anatomia & histologia
Alvéolos Pulmonares/anatomia & histologia
Perda de Dente/fisiopatologia
Dente/anatomia & histologia
Baleias/anatomia & histologia
Baleias/fisiologia
[Mh] Termos MeSH secundário: Animais
Evolução Biológica
Filogenia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171004
[Lr] Data última revisão:
171004
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170526
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0178243


  9 / 2808 MEDLINE  
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[PMID]:28498990
[Au] Autor:Patel S; Thompson KF; Santure AW; Constantine R; Millar CD
[Ad] Endereço:School of Biological Sciences, University of Auckland, Private Bag 92019, Auckland 1142, New Zealand.
[Ti] Título:Genetic Kinship Analyses Reveal That Gray's Beaked Whales Strand in Unrelated Groups.
[So] Source:J Hered;108(4):456-461, 2017 06 01.
[Is] ISSN:1465-7333
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Some marine mammals are so rarely seen that their life history and social structure remain a mystery. Around New Zealand, Gray's beaked whales (Mesoplodon grayi) are almost never seen alive, yet they are a commonly stranded species. Gray's are unique among the beaked whales in that they frequently strand in groups, providing an opportunity to investigate their social organization. We examined group composition and genetic kinship in 113 Gray's beaked whales with samples collected over a 20-year period. Fifty-six individuals stranded in 19 groups (2 or more individuals), and 57 whales stranded individually. Mitochondrial control region haplotypes and microsatellite genotypes (16 loci) were obtained for 103 whales. We estimated pairwise relatedness between all pairs of individuals and average relatedness within, and between, groups. We identified 6 mother-calf pairs and 2 half-siblings, including 2 whales in different strandings 17 years and 1500 km apart. Surprisingly, none of the adults stranding together were related suggesting that groups are not formed through the retention of kin. These data suggest that both sexes may disperse from their mothers, and groups consisting of unrelated subadults are common. We also found no instances of paternity within the groups. Our results provide the first insights into dispersal, social organization, and the mating system in this rarely sighted species. Why whales strand is still unknown but, in Gray's beaked whales, the dead can tell us much about the living.
[Mh] Termos MeSH primário: Genética Populacional
Baleias/genética
[Mh] Termos MeSH secundário: Animais
DNA Mitocondrial/genética
Feminino
Genótipo
Haplótipos
Masculino
Repetições de Microssatélites
Nova Zelândia
Análise de Sequência de DNA
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (DNA, Mitochondrial)
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170907
[Lr] Data última revisão:
170907
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170513
[St] Status:MEDLINE
[do] DOI:10.1093/jhered/esx021


  10 / 2808 MEDLINE  
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[PMID]:28411036
[Au] Autor:Browning CL; Wise CF; Wise JP
[Ad] Endereço:Wise Laboratory of Environmental and Genetic Toxicology, Department of Pharmacology and Toxicology, University of Louisville School of Medicine, 505 S Hancock St, CTRB, Louisville, KY 40292, USA; Graduate School of Biomedical Science and Engineering, University of Maine, 42 Stodder Hall, Orono, ME 04469, USA.
[Ti] Título:Prolonged particulate chromate exposure does not inhibit homologous recombination repair in North Atlantic right whale (Eubalaena glacialis) lung cells.
[So] Source:Toxicol Appl Pharmacol;331:18-23, 2017 Sep 15.
[Is] ISSN:1096-0333
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Chromosome instability is a common feature of cancers that forms due to the misrepair of DNA double strand breaks. Homologous recombination (HR) repair is a high fidelity DNA repair pathway that utilizes a homologous DNA sequence to accurately repair such damage and protect the genome. Prolonged exposure (>72h) to the human lung carcinogen, particulate hexavalent chromium (Cr(VI)), inhibits HR repair, resulting in increased chromosome instability in human cells. Comparative studies have shown acute Cr(VI) exposure induces less chromosome damage in whale cells than human cells, suggesting investigating the effect of this carcinogen in other species may inform efforts to prevent Cr(VI)-induced chromosome instability. Thus, the goal of this study was to determine the effect of prolonged Cr(VI) exposure on HR repair and clastogenesis in North Atlantic right whale (Eubalaena glacialis) lung cells. We show particulate Cr(VI) induces HR repair activity after both acute (24h) and prolonged (120h) exposure in North Atlantic right whale cells. Although the RAD51 response was lower following prolonged Cr(VI) exposure compared to acute exposure, the response was sufficient for HR repair to occur. In accordance with active HR repair, no increase in Cr(VI)-induced clastogenesis was observed with increased exposure time. These results suggest prolonged Cr(VI) exposure affects HR repair and genomic stability differently in whale and human lung cells. Future investigation of the differences in how human and whale cells respond to chemical carcinogens may provide valuable insight into mechanisms of preventing chemical carcinogenesis.
[Mh] Termos MeSH primário: Cromatos/toxicidade
Pulmão/citologia
Pulmão/efeitos dos fármacos
Material Particulado/toxicidade
Reparo de DNA por Recombinação/efeitos dos fármacos
Compostos de Zinco/toxicidade
[Mh] Termos MeSH secundário: Animais
Sobrevivência Celular/efeitos dos fármacos
Sobrevivência Celular/fisiologia
Células Cultivadas
Cromatos/administração & dosagem
Relação Dose-Resposta a Droga
Pulmão/fisiologia
Material Particulado/administração & dosagem
Reparo de DNA por Recombinação/fisiologia
Mucosa Respiratória/efeitos dos fármacos
Mucosa Respiratória/fisiologia
Fatores de Tempo
Baleias
Compostos de Zinco/administração & dosagem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Chromates); 0 (Particulate Matter); 0 (Zinc Compounds); 05F2837HUF (zinc chromate)
[Em] Mês de entrada:1709
[Cu] Atualização por classe:171003
[Lr] Data última revisão:
171003
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170416
[St] Status:MEDLINE



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