Base de dados : MEDLINE
Pesquisa : B01.050.150.900.649.313.988.400.112.199.120.610.600 [Categoria DeCS]
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  1 / 53 MEDLINE  
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[PMID]:28859134
[Au] Autor:Linke M; Bröker F; Ramscar M; Baayen H
[Ad] Endereço:Leibniz Institut für Wissensmedien, Tübingen, Germany.
[Ti] Título:Are baboons learning "orthographic" representations? Probably not.
[So] Source:PLoS One;12(8):e0183876, 2017.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:The ability of Baboons (papio papio) to distinguish between English words and nonwords has been modeled using a deep learning convolutional network model that simulates a ventral pathway in which lexical representations of different granularity develop. However, given that pigeons (columba livia), whose brain morphology is drastically different, can also be trained to distinguish between English words and nonwords, it appears that a less species-specific learning algorithm may be required to explain this behavior. Accordingly, we examined whether the learning model of Rescorla and Wagner, which has proved to be amazingly fruitful in understanding animal and human learning could account for these data. We show that a discrimination learning network using gradient orientation features as input units and word and nonword units as outputs succeeds in predicting baboon lexical decision behavior-including key lexical similarity effects and the ups and downs in accuracy as learning unfolds-with surprising precision. The models performance, in which words are not explicitly represented, is remarkable because it is usually assumed that lexicality decisions, including the decisions made by baboons and pigeons, are mediated by explicit lexical representations. By contrast, our results suggest that in learning to perform lexical decision tasks, baboons and pigeons do not construct a hierarchy of lexical units. Rather, they make optimal use of low-level information obtained through the massively parallel processing of gradient orientation features. Accordingly, we suggest that reading in humans first involves initially learning a high-level system building on letter representations acquired from explicit instruction in literacy, which is then integrated into a conventionalized oral communication system, and that like the latter, fluent reading involves the massively parallel processing of the low-level features encoding semantic contrasts.
[Mh] Termos MeSH primário: Columbidae/fisiologia
Aprendizagem por Discriminação/fisiologia
Papio papio/fisiologia
Reconhecimento Visual de Modelos/fisiologia
[Mh] Termos MeSH secundário: Animais
Seres Humanos
Linguagem
Rede Nervosa/fisiologia
Papio papio/psicologia
Tempo de Reação
Leitura
Semântica
Especificidade da Espécie
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171016
[Lr] Data última revisão:
171016
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170901
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0183876


  2 / 53 MEDLINE  
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[PMID]:28105722
[Au] Autor:Fischer J; Kopp GH; Dal Pesco F; Goffe A; Hammerschmidt K; Kalbitzer U; Klapproth M; Maciej P; Ndao I; Patzelt A; Zinner D
[Ad] Endereço:Cognitive Ethology Laboratory, German Primate Center, Göttingen, Germany.
[Ti] Título:Charting the neglected West: The social system of Guinea baboons.
[So] Source:Am J Phys Anthropol;162 Suppl 63:15-31, 2017 Jan.
[Is] ISSN:1096-8644
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:OBJECTIVES: Primate social systems are remarkably diverse, and thus play a central role in understanding social evolution, including the biological origin of human societies. Although baboons have been prominently featured in this context, historically little was known about the westernmost member of the genus, the Guinea baboon (Papio papio). MATERIAL AND METHODS: Here, we summarize the findings from the first years of observations at the field site CRP Simenti in the Niokolo Koba National Park in Senegal. RESULTS: Guinea baboons reveal a nested multi-level social organization, with reproductive units comprising one "primary" male, one to several females, young, and occasionally "secondary" males at the base of the society. Three to five units form "parties," which team up with other parties to form a "gang." Different gangs have largely overlapping home ranges and agonistic interactions between different parties or gangs are rare. Some but not all strongly socially bonded males are highly related, and population genetic and behavioral evidence indicate female-biased dispersal. Females play an important role in intersexual bond formation and maintenance, and female tenure length varies between a few weeks to several years. DISCUSSION: While the social organization resembles that of hamadryas baboons (P. hamadryas), the social structure differs considerably, specifically in terms of low male aggressiveness and female freedom. Despite substantial differences in social organization and social structure, the acoustic structure of Guinea baboon vocalizations does not differ substantially from that of other baboon taxa. With its multi-level organization, stable bonds between males and females, as well as a high-degree of male-male cooperation and tolerance, Guinea baboons constitute an intriguing model for reconstructing human social evolution.
[Mh] Termos MeSH primário: Comportamento Animal/fisiologia
Evolução Biológica
Papio papio/fisiologia
Comportamento Social
[Mh] Termos MeSH secundário: Animais
Antropologia Física
Feminino
Masculino
Senegal
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1706
[Cu] Atualização por classe:170626
[Lr] Data última revisão:
170626
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170121
[St] Status:MEDLINE
[do] DOI:10.1002/ajpa.23144


  3 / 53 MEDLINE  
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[PMID]:27494254
[Au] Autor:Cooper A; Capewell P; Clucas C; Veitch N; Weir W; Thomson R; Raper J; MacLeod A
[Ad] Endereço:Wellcome Trust Centre for Molecular Parasitology, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom.
[Ti] Título:A Primate APOL1 Variant That Kills Trypanosoma brucei gambiense.
[So] Source:PLoS Negl Trop Dis;10(8):e0004903, 2016 Aug.
[Is] ISSN:1935-2735
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Humans are protected against infection from most African trypanosomes by lipoprotein complexes present in serum that contain the trypanolytic pore-forming protein, Apolipoprotein L1 (APOL1). The human-infective trypanosomes, Trypanosoma brucei rhodesiense in East Africa and T. b. gambiense in West Africa have separately evolved mechanisms that allow them to resist APOL1-mediated lysis and cause human African trypanosomiasis, or sleeping sickness, in man. Recently, APOL1 variants were identified from a subset of Old World monkeys, that are able to lyse East African T. b. rhodesiense, by virtue of C-terminal polymorphisms in the APOL1 protein that hinder that parasite's resistance mechanism. Such variants have been proposed as candidates for developing therapeutic alternatives to the unsatisfactory anti-trypanosomal drugs currently in use. Here we demonstrate the in vitro lytic ability of serum and purified recombinant protein of an APOL1 ortholog from the West African Guinea baboon (Papio papio), which is able to lyse examples of all sub-species of T. brucei including T. b. gambiense group 1 parasites, the most common agent of human African trypanosomiasis. The identification of a variant of APOL1 with trypanolytic ability for both human-infective T. brucei sub-species could be a candidate for universal APOL1-based therapeutic strategies, targeted against all pathogenic African trypanosomes.
[Mh] Termos MeSH primário: Apolipoproteínas/genética
Apolipoproteínas/farmacologia
Variação Genética
Papio papio/genética
Trypanosoma brucei gambiense/efeitos dos fármacos
[Mh] Termos MeSH secundário: África Oriental/epidemiologia
África Ocidental/epidemiologia
Animais
Apolipoproteínas/isolamento & purificação
Apolipoproteínas/metabolismo
Seres Humanos
Proteínas Recombinantes/química
Proteínas Recombinantes/genética
Proteínas Recombinantes/farmacologia
Trypanosoma brucei rhodesiense/efeitos dos fármacos
Tripanossomíase Africana/epidemiologia
Tripanossomíase Africana/parasitologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Apolipoproteins); 0 (Recombinant Proteins)
[Em] Mês de entrada:1707
[Cu] Atualização por classe:170719
[Lr] Data última revisão:
170719
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160806
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pntd.0004903


  4 / 53 MEDLINE  
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[PMID]:26515889
[Au] Autor:Medam T; Fagot J
[Ad] Endereço:Laboratory of Cognitive Psychology, Université d'Aix-Marseille, CNRS, Fédération de recherche 3C, 3 Place Victor Hugo, Bât. 9, Case D, 13331 Marseille cedex, France.
[Ti] Título:Behavioral assessment of combinatorial semantics in baboons (Papio papio).
[So] Source:Behav Processes;123:54-62, 2016 Feb.
[Is] ISSN:1872-8308
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:Combinatorial semantics is a core property of human language whose mechanisms remain poorly known. This study used computerized tasks with touch screens to investigate whether baboons (Papio papio) can understand the combination of shape and color labels in order to designate their corresponding colored shape. The baboons were trained either directly with label-pairs (Experiment 1) or with individual shape and color labels (Experiment 2), before being tested with novel compound labels from which they had to identify the referent. Compound labels understanding was found in one out of seven baboons tested in Experiment 1. Quite surprisingly, none of the 11 baboons showed this capacity in Experiment 2. We discuss several aspects of our protocols which could explain this difference between our two experiments, as well as the significance of our findings for language studies in animals and children.
[Mh] Termos MeSH primário: Comportamento Animal
Formação de Conceito/fisiologia
Papio papio/fisiologia
Semântica
[Mh] Termos MeSH secundário: Animais
Linguagem
Reconhecimento Visual de Modelos/fisiologia
Distribuição Aleatória
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Em] Mês de entrada:1612
[Cu] Atualização por classe:161230
[Lr] Data última revisão:
161230
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:151031
[St] Status:MEDLINE


  5 / 53 MEDLINE  
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[PMID]:26303229
[Au] Autor:Minier L; Fagot J; Rey A
[Ad] Endereço:Cognitive Psychology Laboratory, CNRS and Aix-Marseille University.
[Ti] Título:The Temporal Dynamics of Regularity Extraction in Non-Human Primates.
[So] Source:Cogn Sci;40(4):1019-30, 2016 May.
[Is] ISSN:1551-6709
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Extracting the regularities of our environment is one of our core cognitive abilities. To study the fine-grained dynamics of the extraction of embedded regularities, a method combining the advantages of the artificial language paradigm (Saffran, Aslin, & Newport, ) and the serial response time task (Nissen & Bullemer, ) was used with a group of Guinea baboons (Papio papio) in a new automatic experimental device (Fagot & Bonté, ). After a series of random trials, monkeys were exposed to language-like patterns. We found that the extraction of embedded patterns positioned at the end of larger patterns was faster than the extraction of initial embedded patterns. This result suggests that there is a learning advantage for the final element of a sequence that benefits from the contextual information provided by previous elements.
[Mh] Termos MeSH primário: Comportamento Animal/fisiologia
Cognição/fisiologia
Linguagem
Aprendizagem/fisiologia
Tempo de Reação/fisiologia
[Mh] Termos MeSH secundário: Animais
Feminino
Masculino
Papio papio
Fatores de Tempo
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1705
[Cu] Atualização por classe:170524
[Lr] Data última revisão:
170524
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:150826
[St] Status:MEDLINE
[do] DOI:10.1111/cogs.12279


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[PMID]:26588087
[Au] Autor:Knauf S; Barnett U; Maciej P; Klapproth M; Ndao I; Frischmann S; Fischer J; Zinner D; Liu H
[Ad] Endereço:Work Group Neglected Tropical Diseases, Pathology Unit, German Primate Center, Leibniz-Institute for Primate Research, Göttingen, Germany.
[Ti] Título:High Prevalence of Antibodies against the Bacterium Treponema pallidum in Senegalese Guinea Baboons (Papio papio).
[So] Source:PLoS One;10(11):e0143100, 2015.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:The bacterium Treponema pallidum is known to cause syphilis (ssp. pallidum), yaws (ssp. pertenue), and endemic syphilis (ssp. endemicum) in humans. Nonhuman primates have also been reported to be infected with the bacterium with equally versatile clinical manifestations, from severe skin ulcerations to asymptomatic. At present all simian strains are closely related to human yaws-causing strains, an important consideration for yaws eradication. We tested clinically healthy Guinea baboons (Papio papio) at Parc National Niokolo Koba in south eastern Senegal for the presence of anti-T. pallidum antibodies. Since T. pallidum infection in this species was identified 50 years ago, and there has been no attempt to treat non-human primates for infection, it was hypothesized that a large number of West African baboons are still infected with simian strains of the yaws-bacterium. All animals were without clinical signs of treponematoses, but 18 of 20 (90%) baboons tested positive for antibodies against T. pallidum based on treponemal tests. Yet, Guinea baboons seem to develop no clinical symptoms, though it must be assumed that infection is chronic or comparable to the latent stage in human yaws infection. The non-active character is supported by the low anti-T. pallidum serum titers in Guinea baboons (median = 1:2,560) versus serum titers that are found in genital-ulcerated olive baboons with active infection in Tanzania (range of medians among the groups of initial, moderate, and severe infected animals = 1:15,360 to 1:2.097e+7). Our findings provide evidence for simian infection with T. pallidum in wild Senegalese baboons. Potentially, Guinea baboons in West Africa serve as a natural reservoir for human infection, as the West African simian strain has been shown to cause sustainable yaws infection when inoculated into humans. The present study pinpoints an area where further research is needed to support the currently on-going second WHO led yaws eradication campaign with its goal to eradicate yaws by 2020.
[Mh] Termos MeSH primário: Anticorpos/sangue
Papio papio/sangue
Sífilis/sangue
Treponema pallidum/patogenicidade
[Mh] Termos MeSH secundário: Animais
Anticorpos/imunologia
Seres Humanos
Papio papio/microbiologia
Senegal
Úlcera Cutânea/sangue
Úlcera Cutânea/imunologia
Úlcera Cutânea/patologia
Sífilis/microbiologia
Sífilis/transmissão
Tanzânia
Treponema pallidum/imunologia
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Antibodies)
[Em] Mês de entrada:1606
[Cu] Atualização por classe:151126
[Lr] Data última revisão:
151126
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:151121
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0143100


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[PMID]:26344413
[Au] Autor:Kalbitzer U; Heistermann M; Cheney D; Seyfarth R; Fischer J
[Ad] Endereço:Cognitive Ethology Laboratory, German Primate Center (DPZ), Kellnerweg 4, 37077 Göttingen, Germany; Department of Anthropology and Archaeology, University of Calgary, 2500 University Dr. N.W., Calgary, Alberta T2N 1N4, Canada. Electronic address: urs.kalbitzer@ucalgary.ca.
[Ti] Título:Social behavior and patterns of testosterone and glucocorticoid levels differ between male chacma and Guinea baboons.
[So] Source:Horm Behav;75:100-10, 2015 Sep.
[Is] ISSN:1095-6867
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:In multi-male, multi-female groups of mammals, males usually compete aggressively over access to females. However, species vary in the intensity of male contest competition, which has been linked to differences in testosterone and glucocorticoid profiles. Chacma (Papio ursinus) and Guinea (P. papio) baboons constitute an intriguing model to examine variation in male competition and male endocrine correlates, because of the differences in their social systems. Chacma baboons live in stable female-bonded groups with linear male dominance hierarchies and a high male mating skew, whereas Guinea baboons live in male-bonded, multi-level societies. We recorded male behavior and assayed testosterone (fT) and glucocorticoid metabolite (fGC) levels from fecal samples in one population of each species. Male chacma baboons were more frequently involved in agonistic interactions, and dominance relationships were more consistent than in Guinea baboons, where we could not detect linear hierarchies. Notably, male chacma baboons were also more aggressive towards females, indicating an overall higher aggressiveness in this species. In contrast, male Guinea baboons showed higher levels of affiliative interactions and spatial tolerance. High-ranking and consorting male chacma baboons showed elevated fGC levels and also tended to show elevated fT levels, but there was no effect of consortship in Guinea baboons. Agonism was not related to hormone levels in either species. Thus, predictors of fT and fGC levels in Guinea baboons seem to differ from chacma baboons. Our results support the view that different social systems create differential selection pressures for male aggression, reflected by different hormone profiles.
[Mh] Termos MeSH primário: Glucocorticoides/metabolismo
Papio papio/fisiologia
Papio ursinus/fisiologia
Comportamento Social
Testosterona/metabolismo
[Mh] Termos MeSH secundário: Agressão/fisiologia
Animais
Fezes/química
Feminino
Glucocorticoides/análise
Masculino
Papio papio/metabolismo
Papio ursinus/metabolismo
Reprodução/fisiologia
Predomínio Social
Testosterona/análise
[Pt] Tipo de publicação:COMPARATIVE STUDY; JOURNAL ARTICLE; OBSERVATIONAL STUDY; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Glucocorticoids); 3XMK78S47O (Testosterone)
[Em] Mês de entrada:1606
[Cu] Atualização por classe:151116
[Lr] Data última revisão:
151116
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:150908
[St] Status:MEDLINE


  8 / 53 MEDLINE  
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[PMID]:26232908
[Au] Autor:Malassis R; Gheusi G; Fagot J
[Ad] Endereço:Laboratory of Cognitive Psychology, Aix-Marseille University, Fédération de Recherche 3C, CNRS, 3 Place Victor Hugo, Bât B, Case D, 13331, Marseille Cedex, France. raphaelle.malassis@univ-amu.fr.
[Ti] Título:Assessment of metacognitive monitoring and control in baboons (Papio papio).
[So] Source:Anim Cogn;18(6):1347-62, 2015 Nov.
[Is] ISSN:1435-9456
[Cp] País de publicação:Germany
[La] Idioma:eng
[Ab] Resumo:Metacognition refers to the ability of an organism to evaluate its states of knowledge (metacognitive monitoring) and engage in appropriate information-seeking behaviors when a lack of knowledge is detected (metacognitive control). This study assessed metacognitive monitoring and control in three Guinea baboons (Papio papio). Monkeys were required to report on a touchscreen the location of two target stimuli that had previously appeared briefly on a grid. They could either respond directly or use a "Repeat" key providing an opportunity to repeat the target stimuli. In Experiment 1, the baboons used the Repeat key more frequently in difficult trials and transferred this use of the key to novel conditions. Two baboons showed higher accuracy when they declined using the key compared to Baseline trials in which the key was not available, suggesting accurate metacognitive monitoring judgments. The same two baboons were consistently faster at reporting the targets' locations after a repetition of the stimulus. In Experiment 2, the baboons had to choose between two Repeat keys, one for each target. Two baboons showed a preference for repeating the presentation of the less visible target, suggesting that they identified what information they lack. Overall, results support the hypothesis of metacognitive monitoring in baboons, and also provide limited evidence for metacognitive control. We propose that tests requiring subjects to choose between several metacognitive responses in computerized tasks provide a suitable new approach for studying targeted information-seeking behaviors in animals.
[Mh] Termos MeSH primário: Julgamento
Metacognição
Papio papio/psicologia
[Mh] Termos MeSH secundário: Animais
Comportamento de Busca de Informação
Masculino
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Em] Mês de entrada:1702
[Cu] Atualização por classe:170221
[Lr] Data última revisão:
170221
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:150803
[St] Status:MEDLINE
[do] DOI:10.1007/s10071-015-0907-8


  9 / 53 MEDLINE  
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[PMID]:26194414
[Au] Autor:Pope SM; Meguerditchian A; Hopkins WD; Fagot J
[Ad] Endereço:Neuroscience Institute and Language Research Center, Georgia State University, Atlanta, GA, USA. spope11@student.gsu.edu.
[Ti] Título:Baboons (Papio papio), but not humans, break cognitive set in a visuomotor task.
[So] Source:Anim Cogn;18(6):1339-46, 2015 Nov.
[Is] ISSN:1435-9456
[Cp] País de publicação:Germany
[La] Idioma:eng
[Ab] Resumo:Cognitive set can be both helpful and harmful in problem solving. A large set of similar problems may be solved mechanically by applying a single-solution method. However, efficiency might be sacrificed if a better solution exists and is overlooked. Despite half a century of research on cognitive set, there have been no attempts to investigate whether it occurs in nonhuman species. The current study utilized a nonverbal, computer task to compare cognitive set between 104 humans and 15 baboons (Papio papio). A substantial difference was found between humans' and baboons' abilities to break cognitive set. Consistent with previous studies, the majority of humans were highly impaired by set, yet baboons were almost completely unaffected. Analysis of the human data revealed that children (aged 7-10) were significantly better able to break set than adolescents (11-18) and adults (19-68). Both the evolutionary and developmental implications of these findings are discussed.
[Mh] Termos MeSH primário: Cognição
Papio papio/psicologia
Resolução de Problemas
[Mh] Termos MeSH secundário: Adolescente
Adulto
Idoso
Animais
Evolução Biológica
Criança
Feminino
Seres Humanos
Masculino
Meia-Idade
[Pt] Tipo de publicação:COMPARATIVE STUDY; JOURNAL ARTICLE; RESEARCH SUPPORT, N.I.H., EXTRAMURAL; RESEARCH SUPPORT, NON-U.S. GOV'T
[Em] Mês de entrada:1702
[Cu] Atualização por classe:170221
[Lr] Data última revisão:
170221
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:150722
[St] Status:MEDLINE
[do] DOI:10.1007/s10071-015-0904-y


  10 / 53 MEDLINE  
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[PMID]:26156123
[Au] Autor:Fish I; Boissinot S
[Ad] Endereço:Biology Department, Queens College, the City University of New York, Flushing, NY, USA.
[Ti] Título:Contrasted patterns of variation and evolutionary convergence at the antiviral OAS1 gene in old world primates.
[So] Source:Immunogenetics;67(9):487-99, 2015 Sep.
[Is] ISSN:1432-1211
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:The oligoadenylate synthetase 1 (OAS1) enzyme acts as an innate sensor of viral infection and plays a major role in the defense against a wide diversity of viruses. Polymorphisms at OAS1 have been shown to correlate with differential susceptibility to several infections of great public health significance, including hepatitis C virus, SARS coronavirus, and West Nile virus. Population genetics analyses in hominoids have revealed interesting evolutionary patterns. In Central African chimpanzee, OAS1 has evolved under long-term balancing selection, resulting in the persistence of polymorphisms since the origin of hominoids, whereas human populations have acquired and retained OAS1 alleles from Neanderthal and Denisovan origin. We decided to further investigate the evolution of OAS1 in primates by characterizing intra-specific variation in four species commonly used as models in infectious disease research: the rhesus macaque, the cynomolgus macaque, the olive baboon, and the Guinea baboon. In baboons, OAS1 harbors a very low level of variation. In contrast, OAS1 in macaques exhibits a level of polymorphism far greater than the genomic average, which is consistent with the action of balancing selection. The region of the enzyme that directly interacts with viral RNA, the RNA-binding domain, contains a number of polymorphisms likely to affect the RNA-binding affinity of OAS1. This strongly suggests that pathogen-driven balancing selection acting on the RNA-binding domain of OAS1 is maintaining variation at this locus. Interestingly, we found that a number of polymorphisms involved in RNA-binding were shared between macaques and chimpanzees. This represents an unusual case of convergent polymorphism.
[Mh] Termos MeSH primário: 2´,5´-Oligoadenilato Sintetase/genética
Resistência à Doença/genética
Haplótipos/genética
Polimorfismo Genético/genética
[Mh] Termos MeSH secundário: Sequência de Aminoácidos
Animais
Sequência de Bases
Evolução Molecular
Macaca fascicularis/genética
Macaca fascicularis/imunologia
Macaca mulatta/genética
Macaca mulatta/imunologia
Papio anubis/genética
Papio anubis/imunologia
Papio papio/genética
Papio papio/imunologia
Estrutura Terciária de Proteína
Alinhamento de Sequência
Análise de Sequência de DNA
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, N.I.H., EXTRAMURAL
[Nm] Nome de substância:
EC 2.7.7.84 (2',5'-Oligoadenylate Synthetase)
[Em] Mês de entrada:1605
[Cu] Atualização por classe:170220
[Lr] Data última revisão:
170220
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:150710
[St] Status:MEDLINE
[do] DOI:10.1007/s00251-015-0855-0



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