Base de dados : MEDLINE
Pesquisa : B01.050.150.900.649.313.992.328 [Categoria DeCS]
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[PMID]:29304173
[Au] Autor:Ren P; Li B; Dong S; Chen L; Zhang Y
[Ad] Endereço:Department of Neurosurgery, Xi'an Jiaotong University School of Medicine, Xi'an, People's Republic of China.
[Ti] Título:The reliability of nonlinear least-squares algorithm for data analysis of neural response activity during sinusoidal rotational stimulation in semicircular canal neurons.
[So] Source:PLoS One;13(1):e0190596, 2018.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Although many mathematical methods were used to analyze the neural activity under sinusoidal stimulation within linear response range in vestibular system, the reliabilities of these methods are still not reported, especially in nonlinear response range. Here we chose nonlinear least-squares algorithm (NLSA) with sinusoidal model to analyze the neural response of semicircular canal neurons (SCNs) during sinusoidal rotational stimulation (SRS) over a nonlinear response range. Our aim was to acquire a reliable mathematical method for data analysis under SRS in vestibular system. Our data indicated that the reliability of this method in an entire SCNs population was quite satisfactory. However, the reliability was strongly negatively depended on the neural discharge regularity. In addition, stimulation parameters were the vital impact factors influencing the reliability. The frequency had a significant negative effect but the amplitude had a conspicuous positive effect on the reliability. Thus, NLSA with sinusoidal model resulted a reliable mathematical tool for data analysis of neural response activity under SRS in vestibular system and more suitable for those under the stimulation with low frequency but high amplitude, suggesting that this method can be used in nonlinear response range. This method broke out of the restriction of neural activity analysis under nonlinear response range and provided a solid foundation for future study in nonlinear response range in vestibular system.
[Mh] Termos MeSH primário: Algoritmos
Neurônios/fisiologia
Canais Semicirculares/citologia
[Mh] Termos MeSH secundário: Animais
Chinchila
Feminino
Análise dos Mínimos Quadrados
Dinâmica não Linear
Reprodutibilidade dos Testes
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, N.I.H., EXTRAMURAL
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180215
[Lr] Data última revisão:
180215
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180106
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0190596


  2 / 2739 MEDLINE  
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[PMID]:28467600
[Au] Autor:Arora N; Tripathi S; Kumar P; Mondal P; Mishra A; Prasad A
[Ad] Endereço:School of Basic Sciences, Indian Institute of Technology Mandi, Mandi, India.
[Ti] Título:Recent advancements and new perspectives in animal models for Neurocysticercosis immunopathogenesis.
[So] Source:Parasite Immunol;39(7), 2017 Jul.
[Is] ISSN:1365-3024
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Neurocysticercosis (NCC), one of the most common parasitic diseases of the central nervous system, is caused by Taenia solium. This parasite involves two hosts, intermediate hosts (pig and human) and a definitive host (human) and has various stages in its complex life cycle (eggs, oncosphere, cysticerci and adult tapeworm). Hence, developing an animal model for T. solium that mimics its natural course of infection is quite challenging. We have reviewed here the animal models frequently used to study immunopathogenesis of cysticercosis and also discussed their usefulness for NCC studies. We found that researchers have used mice, rats, guinea pigs, dogs, cats and pigs as models for this disease with varying degrees of success. Mice and rats models have been utilized extensively for immunopathogenesis studies due to their relative ease of handling and abundance of commercially available reagents to study these small animal models. These models have provided some very exciting results for in-depth understanding of the disease. Of late, the experimentally/naturally infected swine model is turning out to be the best animal model as the disease progression closely resembles human infection in pigs. However, handling large experimental animals has its own challenges and limitations.
[Mh] Termos MeSH primário: Modelos Animais de Doenças
Neurocisticercose/imunologia
Taenia solium/imunologia
Taenia/imunologia
Teníase/imunologia
[Mh] Termos MeSH secundário: Animais
Chinchila
Cricetinae
Seres Humanos
Estágios do Ciclo de Vida
Macaca mulatta
Neurocisticercose/parasitologia
Ratos
Suínos
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Em] Mês de entrada:1712
[Cu] Atualização por classe:171228
[Lr] Data última revisão:
171228
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170504
[St] Status:MEDLINE
[do] DOI:10.1111/pim.12439


  3 / 2739 MEDLINE  
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[PMID]:28746468
[Au] Autor:Radojkovic M; Stojanovic M; Stanojevic G; Radojkovic D; Gligorijevic J; Ilic I; Stojanovic N
[Ad] Endereço:Surgery Department, School of Medicine, University of Nis, Nis, Serbia.
[Ti] Título:Ischemic preconditioning vs adenosine vs prostaglandin E1 for protection against liver ischemia/reperfusion injury.
[So] Source:Braz J Med Biol Res;50(8):e6185, 2017 Jul 20.
[Is] ISSN:1414-431X
[Cp] País de publicação:Brazil
[La] Idioma:eng
[Ab] Resumo:Ischemia/reperfusion injury is still a major cause of morbidity and mortality during liver surgery and transplantation. A variety of surgical and pharmacological therapeutic strategies have been investigated to minimize the effects of ischemia/reperfusion. The aim of our study was to analyze and compare preventive influences of ischemic preconditioning, adenosine and prostaglandin E1 in the experimental model of hepatic ischemia/reperfusion injury. Adult chinchilla rabbits were divided into four groups: 10 rabbits subjected to liver ischemic preconditioning (3-min period of inflow occlusion followed by a 5-min period of reperfusion) followed by 45 min of Pringle maneuver; 10 rabbits subjected to pre-treatment with intraportal injection of adenosine followed by 45 min of Pringle maneuver; 10 rabbits subjected to pre-treatment with intraportal injection of prostaglandin E1 followed by 45 min of Pringle maneuver; and control group of 10 rabbits subjected to 45 min of inflow liver ischemia without any preconditioning. On the second postoperative day, blood samples were obtained and biochemical parameters of liver function were measured and compared. Liver tissue samples were also obtained and histopathological changes were compared. Based on biochemical and histopathological parameters, it was demonstrated that ischemic preconditioning provided the best protection against hepatic ischemia/reperfusion injury. This was probably due to a wider range of mechanisms of action of this method oriented to reduce oxidative stress and inflammation, and restore liver microcirculation and hepatocyte energy compared to the examined pharmacological strategies.
[Mh] Termos MeSH primário: Adenosina/uso terapêutico
Alprostadil/uso terapêutico
Precondicionamento Isquêmico/métodos
Hepatopatias/prevenção & controle
Fígado/irrigação sanguínea
Traumatismo por Reperfusão/prevenção & controle
[Mh] Termos MeSH secundário: Animais
Chinchila
Modelos Animais de Doenças
Feminino
Fígado/efeitos dos fármacos
Fígado/patologia
Masculino
[Pt] Tipo de publicação:COMPARATIVE STUDY; JOURNAL ARTICLE
[Nm] Nome de substância:
F5TD010360 (Alprostadil); K72T3FS567 (Adenosine)
[Em] Mês de entrada:1712
[Cu] Atualização por classe:171204
[Lr] Data última revisão:
171204
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170727
[St] Status:MEDLINE


  4 / 2739 MEDLINE  
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[PMID]:28964295
[Au] Autor:Wiedermann JP; Mai JP; Dumont M; Jenkins A; Cleary K; Reilly BK
[Ad] Endereço:The Department of Surgery, Division of Otolaryngology-Head and Neck Surgery, The George Washington University Hospital, Washington, DC, USA. Electronic address: josh.wiedermann@gmail.com.
[Ti] Título:"On-command" dissolvable tympanostomy tube in the chinchilla model: A proof of concept.
[So] Source:Int J Pediatr Otorhinolaryngol;101:20-24, 2017 Oct.
[Is] ISSN:1872-8464
[Cp] País de publicação:Ireland
[La] Idioma:eng
[Ab] Resumo:OBJECTIVES: To prove the concept that a dissolvable "on-command" tympanostomy tube placed into the tympanic membrane of a chinchilla can dissolve when a benign solution is applied and result in a well healed tympanic membrane without histologic evidence of injury. STUDY DESIGN: Prospective Randomized Single-Subject Controlled Trial. METHODS: Prototype tympanostomy tubes were fabricated from poly(butyl methacrylate-co-(2-dimethylaminoethyl) methacrylate-co- methyl methacrylate) (PBM). "In vitro" dissolution studies were performed with applications of the benign chemical, hydrogen peroxide (HP). PBM tubes were placed into ten chinchilla tympanic membranes matched with standard plastic tubes placed into the contralateral side. All 20 tubes were exposed to HP for 21 days with serial endoscopic examinations. In vitro PBM tubes were weighed before and after interventions and compared to control tubes. In vivo photo documentation was used to show progression of dissolution and histologic slides were obtained to show the effect of the PBM on surrounding tissues. RESULTS: Compared to control tubes, all those exposed to hydrogen peroxide had a statistically significant reduction in weight (p < 0.01). After placement into the tympanic membrane of chinchillas, all PBM tubes dissolved within 21 days of hydrogen peroxide treatment leaving behind histologically normal, intact tympanic membranes. CONCLUSION: Our PBM tubes dissolve "on-command" in a chinchilla model when exposed to treatment with a benign chemical. Dissolvable "on-command" tympanostomy tubes may reduce significant complications related to pediatric tympanostomy tube use.
[Mh] Termos MeSH primário: Peróxido de Hidrogênio/farmacologia
Ventilação da Orelha Média/métodos
Membrana Timpânica/cirurgia
[Mh] Termos MeSH secundário: Animais
Chinchila
Estudos Prospectivos
Próteses e Implantes
[Pt] Tipo de publicação:JOURNAL ARTICLE; RANDOMIZED CONTROLLED TRIAL
[Nm] Nome de substância:
BBX060AN9V (Hydrogen Peroxide)
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171023
[Lr] Data última revisão:
171023
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171002
[St] Status:MEDLINE


  5 / 2739 MEDLINE  
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[PMID]:28832600
[Au] Autor:Ewert D; Hu N; Du X; Li W; West MB; Choi CH; Floyd R; Kopke RD
[Ad] Endereço:Hough Ear Institute, Oklahoma City, OK, United States of America.
[Ti] Título:HPN-07, a free radical spin trapping agent, protects against functional, cellular and electrophysiological changes in the cochlea induced by acute acoustic trauma.
[So] Source:PLoS One;12(8):e0183089, 2017.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Oxidative stress is considered a major cause of the structural and functional changes associated with auditory pathologies induced by exposure to acute acoustic trauma AAT). In the present study, we examined the otoprotective effects of 2,4-disulfophenyl-N-tert-butylnitrone (HPN-07), a nitrone-based free radical trap, on the physiological and cellular changes in the auditory system of chinchilla following a six-hour exposure to 4 kHz octave band noise at 105 dB SPL. HPN-07 has been shown to suppress oxidative stress in biological models of a variety of disorders. Our results show that administration of HPN-07 beginning four hours after acoustic trauma accelerated and enhanced auditory/cochlear functional recovery, as measured by auditory brainstem responses (ABR), distortion product otoacoustic emissions (DPOAE), compound action potentials (CAP), and cochlear microphonics (CM). The normally tight correlation between the endocochlear potential (EP) and evoked potentials of CAP and CM were persistently disrupted after noise trauma in untreated animals but returned to homeostatic conditions in HPN-07 treated animals. Histological analyses revealed several therapeutic advantages associated with HPN-07 treatment following AAT, including reductions in inner and outer hair cell loss; reductions in AAT-induced loss of calretinin-positive afferent nerve fibers in the spiral lamina; and reductions in fibrocyte loss within the spiral ligament. These findings support the conclusion that early intervention with HPN-07 following an AAT efficiently blocks the propagative ototoxic effects of oxidative stress, thereby preserving the homeostatic and functional integrity of the cochlea.
[Mh] Termos MeSH primário: Benzenossulfonatos/farmacologia
Cóclea/efeitos dos fármacos
Depuradores de Radicais Livres/farmacologia
Ferimentos e Lesões/fisiopatologia
[Mh] Termos MeSH secundário: Potenciais de Ação
Doença Aguda
Animais
Chinchila
Cóclea/lesões
Cóclea/fisiopatologia
Feminino
Ferimentos e Lesões/patologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Benzenesulfonates); 0 (Free Radical Scavengers); 7M1J3HN9VO (disufenton sodium)
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171019
[Lr] Data última revisão:
171019
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170824
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0183089


  6 / 2739 MEDLINE  
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[PMID]:28796849
[Au] Autor:Schachern PA; Kwon G; Briles DE; Ferrieri P; Juhn S; Cureoglu S; Paparella MM; Tsuprun V
[Ad] Endereço:Department of Otolaryngology University of Minnesota, Minneapolis.
[Ti] Título:Neutrophil Extracellular Traps and Fibrin in Otitis Media: Analysis of Human and Chinchilla Temporal Bones.
[So] Source:JAMA Otolaryngol Head Neck Surg;143(10):990-995, 2017 Oct 01.
[Is] ISSN:2168-619X
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Background: Bacterial resistance in acute otitis can result in bacterial persistence and biofilm formation, triggering chronic and recurrent infections. Objective: To investigate the middle ear inflammatory response to bacterial infection in human and chinchilla temporal bones. Design, Setting, and Participants: Six chinchillas underwent intrabullar inoculations with 0.5 mL of 106 colony-forming units (CFUs) of Streptococcus pneumoniae, serotype 2. Two days later, we counted bacteria in middle ear effusions postmortem. One ear from each chinchilla was processed in paraffin and sectioned at 5 µm. The opposite ear was embedded in epoxy resin, sectioned at a thickness of 1 µm, and stained with toluidine blue. In addition, we examined human temporal bones from 2 deceased donors with clinical histories of otitis media (1 with acute onset otitis media, 1 with recurrent infection). Temporal bones had been previously removed at autopsy, processed, embedded in celloidin, and cut at a thickness of 20 µm. Sections of temporal bones from both chinchillas and humans were stained with hematoxylin-eosin and immunolabeled with antifibrin and antihistone H4 antibodies. Main Outcome Measures: Histopatological and imminohistochemical changes owing to otitis media. Results: Bacterial counts in chinchilla middle ear effusions 2 days after inoculation were approximately 2 logs above initial inoculum counts. Both human and chinchilla middle ear effusions contained bacteria embedded in a fibrous matrix. Some fibers in the matrix showed positive staining with antifibrin antibody, others with antihistone H4 antibody. Conclusions and Relevance: In acute and recurrent otitis media, fibrin and neutrophil extracellular traps (NETs) are part of the host inflammatory response to bacterial infection. In the early stages of otitis media the host defense system uses fibrin to entrap bacteria, and NETs function to eliminate bacteria. In chronic otitis media, fibrin and NETs appear to persist.
[Mh] Termos MeSH primário: Armadilhas Extracelulares
Fibrina
Neutrófilos
Otite Média/patologia
Osso Temporal/patologia
[Mh] Termos MeSH secundário: Animais
Chinchila
Modelos Animais de Doenças
Feminino
Seres Humanos
Lactente
Meia-Idade
Otite Média/microbiologia
Streptococcus pneumoniae/isolamento & purificação
Osso Temporal/microbiologia
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Nm] Nome de substância:
9001-31-4 (Fibrin)
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171031
[Lr] Data última revisão:
171031
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:170811
[St] Status:MEDLINE
[do] DOI:10.1001/jamaoto.2017.1320


  7 / 2739 MEDLINE  
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[PMID]:28674033
[Au] Autor:Pang B; Swords WE
[Ad] Endereço:Department of Microbiology and Immunology, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA.
[Ti] Título:Haemophilus parainfluenzae Strain ATCC 33392 Forms Biofilms and during Experimental Otitis Media Infections.
[So] Source:Infect Immun;85(9), 2017 Sep.
[Is] ISSN:1098-5522
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:is a nutritionally fastidious, Gram-negative bacterium with an oropharyngeal/nasopharyngeal carriage niche that is associated with a range of opportunistic infections, including infectious endocarditis and otitis media (OM). These infections are often chronic/recurrent in nature and typically involve bacterial persistence within biofilm communities that are highly resistant to host clearance. This study addresses the primary hypothesis that forms biofilm communities that are important determinants of persistence The results from biofilm studies confirmed that formed biofilm communities within which the polymeric matrix was mainly composed of extracellular DNA and proteins. Using a chinchilla OM infection model, we demonstrated that formed surface-associated biofilm communities containing bacterial and host components that included neutrophil extracellular trap (NET) structures and that the bacteria mainly persisted in these biofilm communities. We also used this model to examine the possible interaction between and its close relative , which is also commonly carried within the same host environments and can cause OM. The results showed that coinfection with promoted clearance of from biofilm communities during OM infection. The underlying mechanisms for bacterial persistence and biofilm formation by and knowledge about the survival defects of during coinfection with are topics for future work.
[Mh] Termos MeSH primário: Biofilmes/crescimento & desenvolvimento
Infecções por Haemophilus/microbiologia
Haemophilus parainfluenzae/fisiologia
Otite Média/microbiologia
[Mh] Termos MeSH secundário: Animais
Antibiose
Chinchila
Modelos Animais de Doenças
Infecções por Haemophilus/patologia
Haemophilus influenzae/crescimento & desenvolvimento
Haemophilus influenzae/fisiologia
Haemophilus parainfluenzae/crescimento & desenvolvimento
Otite Média/patologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170907
[Lr] Data última revisão:
170907
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170705
[St] Status:MEDLINE


  8 / 2739 MEDLINE  
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[PMID]:28663198
[Au] Autor:Benichoux V; Brown AD; Anbuhl KL; Tollin DJ
[Ad] Endereço:Department of Physiology and Biophysics, victor.benichoux@pasteur.fr.
[Ti] Título:Representation of Multidimensional Stimuli: Quantifying the Most Informative Stimulus Dimension from Neural Responses.
[So] Source:J Neurosci;37(31):7332-7346, 2017 Aug 02.
[Is] ISSN:1529-2401
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:A common way to assess the function of sensory neurons is to measure the number of spikes produced by individual neurons while systematically varying a given dimension of the stimulus. Such measured tuning curves can then be used to quantify the accuracy of the neural representation of the stimulus dimension under study, which can in turn be related to behavioral performance. However, tuning curves often change shape when other dimensions of the stimulus are varied, reflecting the simultaneous sensitivity of neurons to multiple stimulus features. Here we illustrate how one-dimensional information analyses are misleading in this context, and propose a framework derived from Fisher information that allows the quantification of information carried by neurons in multidimensional stimulus spaces. We use this method to probe the representation of sound localization in auditory neurons of chinchillas and guinea pigs of both sexes, and show how heterogeneous tuning properties contribute to a representation of sound source position that is robust to changes in sound level. Sensory neurons' responses are typically modulated simultaneously by numerous stimulus properties, which can result in an overestimation of neural acuity with existing one-dimensional neural information transmission measures. To overcome this limitation, we develop new, compact expressions of Fisher information-derived measures that bound the robust encoding of separate stimulus dimensions in the context of multidimensional stimuli. We apply this method to the problem of the representation of sound source location in the face of changes in sound source level by neurons of the auditory midbrain.
[Mh] Termos MeSH primário: Estimulação Acústica/métodos
Córtex Auditivo/fisiologia
Modelos Neurológicos
Células Receptoras Sensoriais/fisiologia
Localização de Som/fisiologia
[Mh] Termos MeSH secundário: Animais
Chinchila/fisiologia
Simulação por Computador
Sinais (Psicologia)
Mesencéfalo/fisiologia
Rede Nervosa/fisiologia
Análise Espaço-Temporal
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170822
[Lr] Data última revisão:
170822
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170701
[St] Status:MEDLINE
[do] DOI:10.1523/JNEUROSCI.0318-17.2017


  9 / 2739 MEDLINE  
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[PMID]:28482327
[Au] Autor:Kellnerová K; Holubová N; Jandová A; Vejcík A; McEvoy J; Sak B; Kvác M
[Ad] Endereço:Faculty of Agriculture, University of South Bohemia in Ceské Budejovice, 370 05 Ceské Budejovice, Czech Republic.
[Ti] Título:First description of Cryptosporidium ubiquitum XIIa subtype family in farmed fur animals.
[So] Source:Eur J Protistol;59:108-113, 2017 Jun.
[Is] ISSN:1618-0429
[Cp] País de publicação:Germany
[La] Idioma:eng
[Ab] Resumo:This study investigated the prevalence of Cryptosporidium in farmed fur animals in the Czech Republic and Poland. A total of 480 faecal samples were collected from fur animals, including 300 American mink (Mustela vison), 60 silver foxes (Vulpes vulpes), 50 long-tailed chinchillas (Chinchilla lanigera), and 70 nutrias (Myocastor coypus), at 14 farms. Samples were examined for the presence of Cryptosporidium using microscopy (following aniline-carbol-methyl violet staining) and sequence analysis of PCR amplified products. Three mink and two chinchillas from two different farms tested positive for Cryptosporidium ubiquitum DNA. The presence of C. ubiquitum DNA was not associated with diarrhoea. Subtyping of C. ubiquitum isolates by sequence analysis of the 60-kDa glycoprotein gene showed that isolates belonged to the XIIa subtype family, which was previously restricted to humans and ruminants. This suggests that C. ubiquitum subtype XIIa has a broader host range than previously reported.
[Mh] Termos MeSH primário: Animais Domésticos/parasitologia
Cryptosporidium/classificação
[Mh] Termos MeSH secundário: Animais
Chinchila/parasitologia
Cryptosporidium/genética
República Tcheca
DNA de Protozoário/genética
Fezes/parasitologia
Raposas/parasitologia
Vison/parasitologia
Polônia
Especificidade da Espécie
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (DNA, Protozoan)
[Em] Mês de entrada:1707
[Cu] Atualização por classe:170714
[Lr] Data última revisão:
170714
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170509
[St] Status:MEDLINE


  10 / 2739 MEDLINE  
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[PMID]:28340891
[Au] Autor:Kondert L; Mayer J
[Ad] Endereço:Department of Small Animal Medicine and Surgery, College of Veterinary Medicine, University of Georgia, 2200 College Station Road, Athens, GA 30602, USA.
[Ti] Título:Reproductive Medicine in Guinea Pigs, Chinchillas and Degus.
[So] Source:Vet Clin North Am Exot Anim Pract;20(2):609-628, 2017 May.
[Is] ISSN:1558-4232
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Guinea pigs, chinchillas, and degus are hystricomorph rodents originating from South America. They are commonly presented as exotic pets in veterinary practice. Reviewing the anatomy and physiology of their reproductive tract helps to offer better client education about preventive medicine and helps to act faster in emergency situations. Choosing the right anesthetic protocol helps to prevent complications. This article should aid as a guideline on the most common reproductive problems of these 3 species and help in making decisions regarding the best treatment options.
[Mh] Termos MeSH primário: Doenças dos Roedores/diagnóstico
Doenças dos Roedores/terapia
Roedores/fisiologia
[Mh] Termos MeSH secundário: Animais
Animais Exóticos
Chinchila
Feminino
Cobaias
Masculino
Octodon
Reprodução
Medicina Reprodutiva
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Em] Mês de entrada:1706
[Cu] Atualização por classe:170602
[Lr] Data última revisão:
170602
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170326
[St] Status:MEDLINE



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