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  1 / 1610 MEDLINE  
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[PMID]:29211105
[Au] Autor:Tapia-Garay V; Figueroa DP; Maldonado A; Frías-Laserre D; Gonzalez CR; Parra A; Canals L; Apt W; Alvarado S; Cáceres D; Canals M
[Ad] Endereço:Universidad de Chile, Facultad de Medicina, Escuela de Salud Pública, Programa de Salud Ambiental, Santiago, Chile.
[Ti] Título:Assessing the risk zones of Chagas' disease in Chile, in a world marked by global climatic change.
[So] Source:Mem Inst Oswaldo Cruz;113(1):24-29, 2018 Jan.
[Is] ISSN:1678-8060
[Cp] País de publicação:Brazil
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Vector transmission of Trypanosoma cruzi appears to be interrupted in Chile; however, data show increasing incidence of Chagas' disease, raising concerns that there may be a reemerging problem. OBJECTIVE: To estimate the actual risk in a changing world it is necessary to consider the historical vector distribution and correlate this distribution with the presence of cases and climate change. METHODS: Potential distribution models of Triatoma infestans and Chagas disease were performed using Maxent, a machine-learning method. FINDINGS: Climate change appears to play a major role in the reemergence of Chagas' disease and T. infestans in Chile. The distribution of both T. infestans and Chagas' disease correlated with maximum temperature, and the precipitation during the driest month. The overlap of Chagas' disease and T. infestans distribution areas was high. The distribution of T. infestans, under two global change scenarios, showed a minimal reduction tendency in suitable areas. MAIN CONCLUSION: The impact of temperature and precipitation on the distribution of T. infestans, as shown by the models, indicates the need for aggressive control efforts; the current control measures, including T. infestans control campaigns, should be maintained with the same intensity as they have at present, avoiding sylvatic foci, intrusions, and recolonisation of human dwellings.
[Mh] Termos MeSH primário: Mudança Climática
Insetos Vetores/parasitologia
Triatoma/parasitologia
Trypanosoma cruzi/isolamento & purificação
[Mh] Termos MeSH secundário: Animais
Doença de Chagas/transmissão
Chile
Seres Humanos
Modelos Biológicos
Fatores de Risco
[Pt] Tipo de publicação:COMPARATIVE STUDY; JOURNAL ARTICLE
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180131
[Lr] Data última revisão:
180131
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171207
[St] Status:MEDLINE


  2 / 1610 MEDLINE  
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[PMID]:29190728
[Au] Autor:Cohen JE; Rodríguez-Planes LI; Gaspe MS; Cecere MC; Cardinal MV; Gürtler RE
[Ad] Endereço:Laboratory of Populations, Rockefeller University, New York, NY, United States of America.
[Ti] Título:Chagas disease vector control and Taylor's law.
[So] Source:PLoS Negl Trop Dis;11(11):e0006092, 2017 Nov.
[Is] ISSN:1935-2735
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Large spatial and temporal fluctuations in the population density of living organisms have profound consequences for biodiversity conservation, food production, pest control and disease control, especially vector-borne disease control. Chagas disease vector control based on insecticide spraying could benefit from improved concepts and methods to deal with spatial variations in vector population density. METHODOLOGY/PRINCIPAL FINDINGS: We show that Taylor's law (TL) of fluctuation scaling describes accurately the mean and variance over space of relative abundance, by habitat, of four insect vectors of Chagas disease (Triatoma infestans, Triatoma guasayana, Triatoma garciabesi and Triatoma sordida) in 33,908 searches of people's dwellings and associated habitats in 79 field surveys in four districts in the Argentine Chaco region, before and after insecticide spraying. As TL predicts, the logarithm of the sample variance of bug relative abundance closely approximates a linear function of the logarithm of the sample mean of abundance in different habitats. Slopes of TL indicate spatial aggregation or variation in habitat suitability. Predictions of new mathematical models of the effect of vector control measures on TL agree overall with field data before and after community-wide spraying of insecticide. CONCLUSIONS/SIGNIFICANCE: A spatial Taylor's law identifies key habitats with high average infestation and spatially highly variable infestation, providing a new instrument for the control and elimination of the vectors of a major human disease.
[Mh] Termos MeSH primário: Doença de Chagas/transmissão
Controle de Insetos
Modelos Teóricos
Triatoma/fisiologia
[Mh] Termos MeSH secundário: Animais
Ecossistema
Seres Humanos
Insetos Vetores
Análise Espaço-Temporal
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1712
[Cu] Atualização por classe:171228
[Lr] Data última revisão:
171228
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171201
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pntd.0006092


  3 / 1610 MEDLINE  
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[PMID]:29211791
[Au] Autor:Gürtler RE; Fernández MDP; Cecere MC; Cohen JE
[Ad] Endereço:Laboratorio de Eco-Epidemiología, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Buenos Aires, Argentina.
[Ti] Título:Body size and hosts of Triatoma infestans populations affect the size of bloodmeal contents and female fecundity in rural northwestern Argentina.
[So] Source:PLoS Negl Trop Dis;11(12):e0006097, 2017 Dec.
[Is] ISSN:1935-2735
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Human sleeping quarters (domiciles) and chicken coops are key source habitats of Triatoma infestans-the principal vector of the infection that causes Chagas disease-in rural communities in northern Argentina. Here we investigated the links among individual bug bloodmeal contents (BMC, mg), female fecundity, body length (L, mm), host blood sources and habitats. We tested whether L, habitat and host blood conferred relative fitness advantages using generalized linear mixed-effects models and a multimodel inference approach with model averaging. The data analyzed include 769 late-stage triatomines collected in 120 sites from six habitats in 87 houses in Figueroa, Santiago del Estero, during austral spring. L correlated positively with other body-size surrogates and was modified by habitat type, bug stage and recent feeding. Bugs from chicken coops were significantly larger than pig-corral and kitchen bugs. The best-fitting model of log BMC included habitat, a recent feeding, bug stage, log Lc (mean-centered log L) and all two-way interactions including log Lc. Human- and chicken-fed bugs had significantly larger BMC than bugs fed on other hosts whereas goat-fed bugs ranked last, in consistency with average blood-feeding rates. Fecundity was maximal in chicken-fed bugs from chicken coops, submaximal in human- and pig-fed bugs, and minimal in goat-fed bugs. This study is the first to reveal the allometric effects of body-size surrogates on BMC and female fecundity in a large set of triatomine populations occupying multiple habitats, and discloses the links between body size, microsite temperatures and various fitness components that affect the risks of transmission of Trypanosoma cruzi.
[Mh] Termos MeSH primário: Doença de Chagas/transmissão
Insetos Vetores/anatomia & histologia
Triatoma/anatomia & histologia
Trypanosoma/fisiologia
[Mh] Termos MeSH secundário: Animais
Argentina/epidemiologia
Tamanho Corporal
Gatos
Doença de Chagas/epidemiologia
Doença de Chagas/parasitologia
Galinhas
Cães
Ecossistema
Feminino
Fertilidade
Interações Hospedeiro-Parasita
Seres Humanos
Insetos Vetores/fisiologia
Masculino
Distribuição Espacial da População
População Rural
Estações do Ano
Suínos
Temperatura Ambiente
Triatoma/fisiologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1712
[Cu] Atualização por classe:171226
[Lr] Data última revisão:
171226
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171207
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pntd.0006097


  4 / 1610 MEDLINE  
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[PMID]:29176770
[Au] Autor:Dario MA; Lisboa CV; Costa LM; Moratelli R; Nascimento MP; Costa LP; Leite YLR; Llewellyn MS; Xavier SCDC; Roque ALR; Jansen AM
[Ad] Endereço:Laboratório de Biologia de Tripanosomatídeos, Instituto Oswaldo Cruz, Fundação Oswaldo Cruz, Rio de Janeiro/RJ, Brazil.
[Ti] Título:High Trypanosoma spp. diversity is maintained by bats and triatomines in Espírito Santo state, Brazil.
[So] Source:PLoS One;12(11):e0188412, 2017.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:The aim of this study was to reevaluate the ecology of an area in the Atlantic Forest, southeast Brazil, where Chagas disease (CD) has been found to occur. In a previous study, immediately after the occurrence of a CD case, we did not observe any sylvatic small mammals or dogs with Trypanosoma cruzi cruzi infections, but Triatoma vitticeps presented high T. c. cruzi infection rates. In this study, we investigated bats together with non-volant mammals, dogs, and triatomines to explore other possible T. c. cruzi reservoirs/hosts in the area. Seventy-three non-volant mammals and 186 bats were captured at three sites within the Guarapari municipality, Espírito Santo state. Rio da Prata and Amarelos sites exhibited greater richness in terms of non-volant mammals and bats species, respectively. The marsupial Metachirus nudicaudatus, the rodent Trinomys paratus, and the bats Artibeus lituratus and Carollia perspicillata were the most frequently captured species. As determined by positive hemocultures, only two non-volant mammals were found to be infected by Trypanosoma species: Monodelphis americana, which was infected by T. cascavelli, T. dionisii and Trypanosoma sp., and Callithrix geoffroyi, which was infected by T. minasense. Bats presented T. c. cruzi TcI and TcIII/V, T. c. marinkellei, T. dionisii, T. rangeli B and D, and Trypanosoma sp. infections. Seven dogs were infected with T. cruzi based only on serological exams. The triatomines T. vitticeps and Panstrongylus geniculatus were found to be infected by trypanosomes via microscopy. According to molecular characterization, T. vitticeps specimens were infected with T. c. cruzi TcI, TcII, TcIII/V, and TcIV, T. c. marinkellei and T. dionisii. We observed high trypanosome diversity in a small and fragmented region of the Atlantic Forest. This diversity was primarily maintained by bats and T. vitticeps. Our findings show that the host specificity of the Trypanosoma genus should be thoroughly reviewed. In addition, our data show that CD cases can occur without an enzootic cycle near residential areas.
[Mh] Termos MeSH primário: Biodiversidade
Quirópteros/parasitologia
Triatoma/parasitologia
Trypanosoma/fisiologia
[Mh] Termos MeSH secundário: Animais
Sequência de Bases
Brasil/epidemiologia
Cães
Geografia
Sequenciamento de Nucleotídeos em Larga Escala
Intestinos/parasitologia
Filogenia
RNA Ribossômico/genética
Floresta Úmida
Especificidade da Espécie
Tripanossomíase/epidemiologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (RNA, Ribosomal)
[Em] Mês de entrada:1712
[Cu] Atualização por classe:171219
[Lr] Data última revisão:
171219
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171128
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0188412


  5 / 1610 MEDLINE  
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[PMID]:28957315
[Au] Autor:Dorn PL; McClure AG; Gallaspy MD; Waleckx E; Woods AS; Monroy MC; Stevens L
[Ad] Endereço:Loyola University New Orleans, New Orleans, Louisiana, United States of America.
[Ti] Título:The diversity of the Chagas parasite, Trypanosoma cruzi, infecting the main Central American vector, Triatoma dimidiata, from Mexico to Colombia.
[So] Source:PLoS Negl Trop Dis;11(9):e0005878, 2017 Sep.
[Is] ISSN:1935-2735
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Little is known about the strains of Trypanosoma cruzi circulating in Central America and specifically in the most important vector in this region, Triatoma dimidiata. Approximately six million people are infected with T. cruzi, the causative agent of Chagas disease, which has the greatest negative economic impact and is responsible for ~12,000 deaths annually in Latin America. By international consensus, strains of T. cruzi are divided into six monophyletic clades called discrete typing units (DTUs TcI-VI) and a seventh DTU first identified in bats called TcBat. TcI shows the greatest geographic range and diversity. Identifying strains present and diversity within these strains is important as different strains and their genotypes may cause different pathologies and may circulate in different localities and transmission cycles, thus impacting control efforts, treatment and vaccine development. To determine parasite strains present in T. dimidiata across its geographic range from Mexico to Colombia, we isolated abdominal DNA from T. dimidiata and determined which specimens were infected with T. cruzi by PCR. Strains from infected insects were determined by comparing the sequence of the 18S rDNA and the spliced-leader intergenic region to typed strains in GenBank. Two DTUs were found: 94% of infected T. dimidiata contained TcI and 6% contained TcIV. TcI exhibited high genetic diversity. Geographic structure of TcI haplotypes was evident by Principal Component and Median-Joining Network analyses as well as a significant result in the Mantel test, indicating isolation by distance. There was little evidence of association with TcI haplotypes and host/vector or ecotope. This study provides new information about the strains circulating in the most important Chagas vector in Central America and reveals considerable variability within TcI as well as geographic structuring at this large geographic scale. The lack of association with particular vectors/hosts or ecotopes suggests the parasites are moving among vectors/hosts and ecotopes therefore a comprehensive approach, such as the Ecohealth approach that makes houses refractory to the vectors will be needed to successfully halt transmission of Chagas disease.
[Mh] Termos MeSH primário: Doença de Chagas/parasitologia
Variação Genética
Insetos Vetores/parasitologia
Triatoma/parasitologia
Trypanosoma cruzi/genética
[Mh] Termos MeSH secundário: Animais
Doença de Chagas/epidemiologia
Doença de Chagas/transmissão
Quirópteros/parasitologia
Colômbia/epidemiologia
Genótipo
Haplótipos
Seres Humanos
México/epidemiologia
Filogenia
Trypanosoma cruzi/classificação
Trypanosoma cruzi/isolamento & purificação
Trypanosoma cruzi/fisiologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171023
[Lr] Data última revisão:
171023
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170929
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pntd.0005878


  6 / 1610 MEDLINE  
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[PMID]:28953998
[Au] Autor:Carbajal-de-la-Fuente AL; Provecho YM; Fernández MDP; Cardinal MV; Lencina P; Spillmann C; Gürtler RE
[Ad] Endereço:University of Buenos Aires, Institute of Ecology, Genetics and Evolution of Buenos Aires, Faculty of Exact and Natural Sciences, National Scientific and Technical Research Council, Ciudad Autónoma de Buenos Aires, Argentina.
[Ti] Título:The eco-epidemiology of Triatoma infestans in the temperate Monte Desert ecoregion of mid-western Argentina.
[So] Source:Mem Inst Oswaldo Cruz;112(10):698-708, 2017 Oct.
[Is] ISSN:1678-8060
[Cp] País de publicação:Brazil
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: The eco-epidemiological status of Chagas disease in the Monte Desert ecoregion of western Argentina is largely unknown. We investigated the environmental and socio-demographic determinants of house infestation with Triatoma infestans, bug abundance, vector infection with Trypanosoma cruzi and host-feeding sources in a well-defined rural area of Lavalle Department in the Mendoza province. METHODS: Technical personnel inspected 198 houses for evidence of infestation with T. infestans, and the 76 houses included in the current study were re-inspected. In parallel with the vector survey, an environmental and socio-demographic survey was also conducted. Univariate risk factor analysis for domiciliary infestation was carried out using Firth penalised logistic regression. We fitted generalised linear models for house infestation and bug abundance. Blood meals were tested with a direct ELISA assay, and T. cruzi infection was determined using a hot-start polymerase chain reaction (PCR) targeting the kinetoplast minicircle (kDNA-PCR). FINDINGS: The households studied included an aged population living in precarious houses whose main economic activities included goat husbandry. T. infestans was found in 21.2% of 198 houses and in 55.3% of the 76 re-inspected houses. Peridomestic habitats exhibited higher infestation rates and bug abundances than did domiciles, and goat corrals showed high levels of infestation. The main host-feeding sources were goats. Vector infection was present in 10.2% of domiciles and 3.2% of peridomiciles. Generalised linear models showed that peridomestic infestation was positively and significantly associated with the presence of mud walls and the abundance of chickens and goats, and bug abundance increased with the number of all hosts except rabbits. MAIN CONCLUSIONS: We highlight the relative importance of specific peridomestic structures (i.e., goat corrals and chicken coops) associated with construction materials and host abundance as sources of persistent bug infestation driving domestic colonisation. Environmental management strategies framed in a community-based programme combined with improved insecticide spraying and sustained vector surveillance are needed to effectively suppress local T. infestans populations.
[Mh] Termos MeSH primário: Comportamento Alimentar/fisiologia
Insetos Vetores/fisiologia
Triatoma/fisiologia
[Mh] Termos MeSH secundário: Adulto
Idoso
Animais
Argentina
Gatos
Doença de Chagas/transmissão
Galinhas
Cães
Feminino
Cabras
Seres Humanos
Insetos Vetores/parasitologia
Masculino
Meia-Idade
Densidade Demográfica
Fatores de Risco
População Rural
Fatores Socioeconômicos
Triatoma/parasitologia
Trypanosoma cruzi/isolamento & purificação
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1711
[Cu] Atualização por classe:171109
[Lr] Data última revisão:
171109
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170928
[St] Status:MEDLINE


  7 / 1610 MEDLINE  
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[PMID]:28829725
[Au] Autor:de Arias AR; Carbajal de la Fuente AL; Gómez A; Cecere MC; Rolón M; Gómez MCV; Villalba C
[Ad] Endereço:Centro para el Desarrollo de la Investigación Científica (CEDIC), Diaz Gill Medicina Laboratorial/Fundación Moisés Bertoni, Asunción, Paraguay.
[Ti] Título:Morphometric Wings Similarity among Sylvatic and Domestic Populations of Triatoma infestans .
[So] Source:Am J Trop Med Hyg;97(2):481-488, 2017 Aug.
[Is] ISSN:1476-1645
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Despite sustained efforts for eliminating , reinfestation still persists in large part of the endemic area of Chagas disease from the Gran Chaco region. Sylvatic populations seem to threat success of control programs of domestic . In this study, we analyze whether collected after a community-wide spraying were survivors or were immigrants from elsewhere using geometric morphometric tools. We used 101 right wings of female captured before and after intervention program carried out in 12 de Junio and Casuarina, villages from Paraguayan Chaco, and in Puerto Casado during presprayed collection. There were no significant differences in wing size of domestic between pre- and postspraying populations, and between domestic and sylvatic ones. When shape variables originating from postintervention individuals from 12 de Junio were introduced one by one into a discriminant analysis, the greatest weight (53%) was allocated to the sylvatic group. Furthermore, from the prespraying population, 25% were reallocated as postintervention individuals. Only 11% of the insects were reassigned to other groups Puerto Casado and Casuarina. These results suggest that postspraying individuals appear to have different origins. Half of the postspraying individuals from 12 de Junio were similar to the sylvatic ones and 25% of these were similar to those captured in the prespraying period. This remarkable morphometric wings similarity between sylvatic and domestic populations is new evidence suggesting that they could be highly related to each other in the Paraguayan Chaco; human-fed bugs from sylvatic area also support this.
[Mh] Termos MeSH primário: Animais Domésticos/anatomia & histologia
Animais Selvagens/anatomia & histologia
Insetos Vetores/anatomia & histologia
Triatoma/anatomia & histologia
Asas de Animais/anatomia & histologia
[Mh] Termos MeSH secundário: Animais
Feminino
Paraguai
[Pt] Tipo de publicação:COMPARATIVE STUDY; JOURNAL ARTICLE
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170911
[Lr] Data última revisão:
170911
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:170823
[St] Status:MEDLINE
[do] DOI:10.4269/ajtmh.16-1013


  8 / 1610 MEDLINE  
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[PMID]:28822204
[Au] Autor:Monteon V; May-Gil I; Acosta-Viana K; Ramos-Logonio A; Hernandez O; Lopez R
[Ad] Endereço:Centro Investigaciones Biomedicas, Universidad Autonoma Campeche, Patricio Trueba s/n, Campeche 24090, Mexico
[Ti] Título:Comparative 2-D electrophoresis of salivary proteins in Triatoma dimidiata and Rhodnius prolixus (Hemiptera: Reduviidae) and major cross-reactive antigens
[So] Source:Ann Parasitol;63(2):121-125, 2017.
[Is] ISSN:2299-0631
[Cp] País de publicação:Poland
[La] Idioma:eng
[Ab] Resumo:An immune response to triatomine's saliva is an immunological marker of exposure to triatomine bites. However, considerable variability in salivary protein profiles did exist among species. In the present work, we compare salivary proteins from Mexican Triatoma dimidiata and Rhodnius prolixus using 2-D electrophoresis. A clear differential saliva profile was found to exist between these two triatomine species. Fewer protein spots were detected in R. prolixus than in T. dimidiata. More than half of the proteins had an isoelectric point between 5 and 7 and a molecular weight between 10 and 30 kDa in T. dimidiata. Mice exposed to T. dimidiata saliva mount an immune response to three major cross-reacting antigens in R. prolixius saliva with weights of 10 kDa and 55 kDa. Our findings may alert for the presence of cross-reacting antigens between triatomine species in regions where two or more species are overlapping in the same geographical area.
[Mh] Termos MeSH primário: Antígenos/metabolismo
Proteínas de Insetos/metabolismo
Rhodnius/metabolismo
Proteínas e Peptídeos Salivares/metabolismo
Triatoma/metabolismo
[Mh] Termos MeSH secundário: Animais
Eletroforese em Gel Bidimensional
Proteínas de Insetos/genética
Proteínas e Peptídeos Salivares/genética
Especificidade da Espécie
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Antigens); 0 (Insect Proteins); 0 (Salivary Proteins and Peptides)
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171017
[Lr] Data última revisão:
171017
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170820
[St] Status:MEDLINE
[do] DOI:10.17420/ap6302.95


  9 / 1610 MEDLINE  
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[PMID]:28723933
[Au] Autor:Pita S; Panzera F; Mora P; Vela J; Cuadrado Á; Sánchez A; Palomeque T; Lorite P
[Ad] Endereço:Sección Genética Evolutiva, Facultad de Ciencias, Universidad de la República, Montevideo, Uruguay.
[Ti] Título:Comparative repeatome analysis on Triatoma infestans Andean and Non-Andean lineages, main vector of Chagas disease.
[So] Source:PLoS One;12(7):e0181635, 2017.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Triatoma infestans is the most important Chagas disease vector in South America. Two main evolutionary lineages, named Andean and non-Andean, have been recognized by geographical distribution, phenetic and genetic characteristics. One of the main differences is the genomic size, varying over 30% in their haploid DNA content. Here we realize a genome wide analysis to compare the repetitive genome fraction (repeatome) between both lineages in order to identify the main repetitive DNA changes occurred during T. infestans differentiation process. RepeatExplorer analysis using Illumina reads showed that both lineages exhibit the same amount of non-repeat sequences, and that satellite DNA is by far the major component of repetitive DNA and the main responsible for the genome size differentiation between both lineages. We characterize 42 satellite DNA families, which are virtually all present in both lineages but with different amount in each lineage. Furthermore, chromosomal location of satellite DNA by fluorescence in situ hybridization showed that genomic variations in T. infestans are mainly due to satellite DNA families located on the heterochromatic regions. The results also show that many satDNA families are located on the euchromatic regions of the chromosomes.
[Mh] Termos MeSH primário: Doença de Chagas/transmissão
Insetos Vetores/genética
Triatoma/genética
[Mh] Termos MeSH secundário: Animais
Hibridização in Situ Fluorescente
Filogenia
América do Sul
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170926
[Lr] Data última revisão:
170926
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170721
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0181635


  10 / 1610 MEDLINE  
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[PMID]:28722589
[Au] Autor:Blariza MJ; Grosso CG; García BA
[Ad] Endereço:Instituto de Investigaciones en Ciencias de la Salud (INICSA), Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Cátedra de Bioquímica y Biología Molecular, Facultad de Ciencias Médicas, Universidad Nacional de Córdoba, Córdoba, Argentina.
[Ti] Título:Silencing of Two Vitellogenin Genes Inhibits Oviposition in the Chagas Disease Vector (Hemiptera: Reduviidae).
[So] Source:Am J Trop Med Hyg;97(2):477-480, 2017 Aug.
[Is] ISSN:1476-1645
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:RNA interference caused by exogenous double-stranded RNA (dsRNA) is used to downregulate crucial genes to control insects. The reproductive success of all oviparous species depends on vitellogenin (Vg) biosynthesis and its accumulation in the developing oocytes. Adult females of were independently injected with two dsRNAs ( dsRNA or dsRNA) or nuclease-free water (control) 24 hours before feeding, and a group of adult females not injected was also analyzed (control). and messenger RNAs silencing was verified by reverse transcription quantitative polymerase chain reaction. The transcript levels of the and genes were significantly reduced after dsRNA treatment in fat body and ovary of in relation to those detected in individuals injected with nuclease-free water and not injected (controls). Moreover, the present study demonstrated that the silencing of the or genes inhibits oviposition in the Chagas disease vector . These findings may have important implications for the development of novel vector control strategies.
[Mh] Termos MeSH primário: Doença de Chagas/transmissão
Inativação Gênica
Insetos Vetores/genética
Oviposição/genética
Triatoma/genética
Vitelogeninas/biossíntese
Vitelogeninas/genética
[Mh] Termos MeSH secundário: Animais
Feminino
Expressão Gênica
Genes de Insetos
Controle de Insetos/métodos
[Pt] Tipo de publicação:COMPARATIVE STUDY; JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Vitellogenins)
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170911
[Lr] Data última revisão:
170911
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:170720
[St] Status:MEDLINE
[do] DOI:10.4269/ajtmh.16-1029



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