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[PMID]:29324760
[Au] Autor:Poché DM; Garlapati RB; Mukherjee S; Torres-Poché Z; Hasker E; Rahman T; Bharti A; Tripathi VP; Prakash S; Chaubey R; Poché RM
[Ad] Endereço:Department of Vector Ecology, Genesis Laboratories, Inc., Wellington, United States of America.
[Ti] Título:Bionomics of Phlebotomus argentipes in villages in Bihar, India with insights into efficacy of IRS-based control measures.
[So] Source:PLoS Negl Trop Dis;12(1):e0006168, 2018 01.
[Is] ISSN:1935-2735
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Visceral leishmaniasis (VL) is a deadly vector-borne disease. Approximately 90% of Indian VL cases occur in Bihar, where the sand fly, Phlebotomus argentipes, is the principal vector. Sand fly control in Bihar consists of indoor residual spraying (IRS), the practice of spraying the inner walls of village dwellings with insecticides. Prior researchers have evaluated success of IRS-control by estimating vector abundance in village houses, but the number of sampling periods (n = 2-3) were minimal, and outdoor-resting P. argentipes were neglected. We describe a large-scale field study, performed in 24 villages within two Bihari districts, during which P. argentipes were collected biweekly over 47-weeks, in cattle enclosures, houses, and outdoors in peri-domestic vegetation. The objectives of this study were to provide updated P. argentipes ecological field data, and determine if program-initiated IRS-treatment had led to noticeable differences in vector abundance. PRINCIPAL FINDINGS: P. argentipes (n = 126,901) relative abundance was greatest during the summer months (June-August) when minimum temperatures were highest. P. argentipes were most frequently collected from cattle enclosures (~46% total; ~56% blood fed). Many sand flies were found to have taken blood from multiple sources, with ~81% having blood fed on humans and ~60% blood feeding on bovines. Nonparametric statistical tests were determined most appropriate for evaluating IRS-treatment. Differences in P. argentipes abundance in houses, cattle enclosures and vegetation were detected between IRS-treated and untreated villages in only ~9% of evaluation periods occurring during the peak period of human-vector exposure (June-August) and in ~8% of the total observations. No significant differences were detected between the numbers of P. argentipes collected in vegetation close to the experimental villages. CONCLUSION: The results of this study provide updated data regarding P. argentipes seasonal abundance, spatial distribution, and host preferances, and suggest vector abundance has not significantly declined in IRS-treated villages. We suggest that IRS be supplemented with vector control strategies targeting exophagic, exophilic P. argentipes, and that disease surveillance be accompanied by rigorous vector population monitoring.
[Mh] Termos MeSH primário: Controle de Insetos/métodos
Insetos Vetores/efeitos dos fármacos
Inseticidas/farmacologia
Leishmaniose Visceral/prevenção & controle
Leishmaniose Visceral/transmissão
Phlebotomus/efeitos dos fármacos
[Mh] Termos MeSH secundário: Animais
Meio Ambiente
Seres Humanos
Índia/epidemiologia
Insetos Vetores/parasitologia
Leishmania donovani
Leishmaniose Visceral/epidemiologia
Leishmaniose Visceral/parasitologia
Phlebotomus/parasitologia
Estações do Ano
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Insecticides)
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180130
[Lr] Data última revisão:
180130
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180112
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pntd.0006168


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[PMID]:27771421
[Au] Autor:Yared S; Gebresilassie A; Akililu E; Balkew M; Warburg A; Hailu A; Gebre-Michael T
[Ad] Endereço:Aklilu Lemma Institute of Pathobiology, Addis Ababa University, Addis Ababa, Ethiopia; Department of Biology, College of Natural and Computational Sciences, Jigjiga University, Jigjiga, Ethiopia. Electronic address: solyar2005@yahoo.com.
[Ti] Título:Habitat preference and seasonal dynamics of Phlebotomus orientalis in urban and semi-urban areas of kala-azar endemic district of Kafta Humera, northwest Ethiopia.
[So] Source:Acta Trop;166:25-34, 2017 Feb.
[Is] ISSN:1873-6254
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:Visceral leishmaniasis is a significant public health problem in northwest Ethiopia, particularly in Kafta Humera district. The study was designed to determine the species composition and population dynamics of sand flies in five villages representing urban and semi-urban areas of Kafta Humera district namely, Setit Humera, Mykadra, Rawyan, Bereket and Adebay. Sand flies were collected for two to three nights monthly from May 2011 to April 2012 using CDC light-traps and sticky traps. Traps were placed in villages, at periphery of villages and farm fields. Sticky traps were also used for sampling indoor active sand flies. In total, 13,097 sand fly specimens of eight Phlebotomus species and 91,949 Sergentomyia specimens were collected. Among the Phlebotomus, P. orientalis was the predominant species (58.1%) followed by P. papatasi (29.6%), P. lesleyae (5.6%), P. bergeroti (3.8%), P. duboscqi (2.1%), P. alexandri (0.4%), P. heischi (0.2%) and P. rodhaini (0.2%). Significantly, higher number of P. orientalis was caught in Adebay village and the least in Setit Humera town. Seasonal abundance of P. orientalis increased during the dry season (January-May) and dropped drastically in the wet season (late June-September). Significant positive correlation was found between monthly abundance of P. orientalis and the monthly average air and surface soil temperature, while a negative correlation was found with monthly average rainfall and relative humidity. Higher number of P. orientalis was collected outdoors, especially in the farm fields followed by periphery of villages. Thus, various observations strongly suggested P. orientalis to be the principal vector in the study areas, where farm lands and periphery of villages were identified as the most risky habitats, whereas the indoors were the least ones. Appropriate control methods should be designed and implemented according to the knowledge of P. orientalis habitat preferences and seasonal dynamics in the district.
[Mh] Termos MeSH primário: Insetos Vetores/classificação
Leishmaniose Visceral/epidemiologia
Phlebotomus/classificação
[Mh] Termos MeSH secundário: Animais
Ecossistema
Etiópia/epidemiologia
Feminino
Insetos Vetores/fisiologia
Leishmaniose Visceral/transmissão
Masculino
Phlebotomus/fisiologia
Dinâmica Populacional
Estações do Ano
Temperatura Ambiente
População Urbana
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1702
[Cu] Atualização por classe:171216
[Lr] Data última revisão:
171216
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161025
[St] Status:MEDLINE


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[PMID]:29023574
[Au] Autor:Kammoun-Rebai W; Bahi-Jaber N; Naouar I; Toumi A; Ben Salah A; Louzir H; Meddeb-Garnaoui A
[Ad] Endereço:Laboratory of Medical Parasitology, Biotechnologies and Biomolecules, Institut Pasteur de Tunis, Tunis, Tunisia.
[Ti] Título:Human cellular and humoral immune responses to Phlebotomus papatasi salivary gland antigens in endemic areas differing in prevalence of Leishmania major infection.
[So] Source:PLoS Negl Trop Dis;11(10):e0005905, 2017 Oct.
[Is] ISSN:1935-2735
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Sand fly saliva compounds are able to elicit specific immune responses that have a significant role in Leishmania parasite establishment and disease outcome. Characterizing anti-saliva immune responses in individuals living in well defined leishmaniasis endemic areas would provide valuable insights regarding their effect on parasite transmission and establishment in humans. METHODOLOGY/PRINCIPAL FINDINGS: We explored the cellular and humoral immune responses to Phlebotomus (P.) papatasi salivary gland extracts (SGE) in individuals living in cutaneous leishmaniasis (CL) old or emerging foci (OF, EF). OF was characterized by a higher infection prevalence as assessed by higher proportions of leishmanin skin test (LST) positive individuals compared to EF. Subjects were further subdivided into healed, asymptomatic or naïve groups. We showed anti-SGE proliferation in less than 30% of the individuals, regardless of the immune status, in both foci. IFN-γ production was higher in OF and only observed in immune individuals from OF and naïve subjects from EF. Although IL-10 was not detected, addition of anti-human IL-10 antibodies revealed an increase in proliferation and IFN-γ production only in individuals from OF. The percentage of seropositive individuals was similar in immune and naïves groups but was significantly higher in OF. No correlation was observed between anti-saliva immune responses and LST response. High anti-SGE-IgG responses were associated with an increased risk of developing ZCL. No differences were observed for anti-SGE humoral or cellular responses among naïve individuals who converted or not their LST response or developed or not ZCL after the transmission season. CONCLUSIONS/SIGNIFICANCE: These data suggest that individuals living in an old focus characterized by a frequent exposure to sand fly bites and a high prevalence of infection, develop higher anti-saliva IgG responses and IFN-γ levels and a skew towards a Th2-type cellular response, probably in favor of parasite establishment, compared to those living in an emerging focus.
[Mh] Termos MeSH primário: Antígenos/imunologia
Imunidade Celular
Imunidade Humoral
Proteínas de Insetos/imunologia
Leishmaniose Cutânea/epidemiologia
Phlebotomus/imunologia
Proteínas e Peptídeos Salivares/imunologia
[Mh] Termos MeSH secundário: Adolescente
Animais
Infecções Assintomáticas/epidemiologia
Criança
Doenças Endêmicas
Feminino
Seres Humanos
Imunoglobulina G/sangue
Mordeduras e Picadas de Insetos
Interferon gama/imunologia
Interleucina-10/biossíntese
Interleucina-10/imunologia
Leishmania major/imunologia
Leishmaniose Cutânea/imunologia
Leishmaniose Cutânea/parasitologia
Leishmaniose Cutânea/transmissão
Masculino
Prevalência
Saliva/química
Saliva/imunologia
Proteínas e Peptídeos Salivares/química
Células Th2
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Antigens); 0 (IL10 protein, human); 0 (Immunoglobulin G); 0 (Insect Proteins); 0 (Salivary Proteins and Peptides); 130068-27-8 (Interleukin-10); 82115-62-6 (Interferon-gamma)
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171105
[Lr] Data última revisão:
171105
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171013
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pntd.0005905


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[PMID]:29023446
[Au] Autor:Hirve S; Kroeger A; Matlashewski G; Mondal D; Banjara MR; Das P; Be-Nazir A; Arana B; Olliaro P
[Ad] Endereço:Global Influenza Programme, World Health Organization, Geneva, Switzerland.
[Ti] Título:Towards elimination of visceral leishmaniasis in the Indian subcontinent-Translating research to practice to public health.
[So] Source:PLoS Negl Trop Dis;11(10):e0005889, 2017 Oct.
[Is] ISSN:1935-2735
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: The decade following the Regional Strategic Framework for Visceral Leishmaniasis (VL) elimination in 2005 has shown compelling progress in the reduction of VL burden in the Indian subcontinent. The Special Programme for Research and Training in Tropical Diseases (TDR), hosted by the World Health Organization (WHO) and other stakeholders, has coordinated and financed research for the development of new innovative tools and strategies to support the regional VL elimination initiative. This paper describes the process of the TDR's engagement and contribution to this initiative. METHODOLOGY/PRINCIPAL FINDINGS: Multiple databases were searched to identify 152 scientific papers and reports with WHO funding or authorship affiliation around the following 3 framework strategies: detection of new cases, morbidity reduction, and prevention of infection. TDR has played a critical role in the evaluation and subsequent use of the 39-aminoacid-recombinant kinesin antigen (rK39) rapid diagnostic test (RDT) as a confirmatory test for VL in the national program. TDR has supported the clinical research and development of miltefosine and single-dose liposomal amphotericin B as a first-line treatment against VL. TDR has engaged with in-country researchers, national programme managers, and partners to generate evidence-based interventions for early detection and treatment of VL patients. TDR evaluated the quality, community acceptance, and cost effectiveness of indoor residual spraying, insecticide-treated bed nets, insecticide-impregnated durable wall linings, insecticidal paint, and environmental management as tools for integrated vector management in reducing sandfly density. CONCLUSIONS/SIGNIFICANCE: TDR's engagement with country policy makers, scientists, and clinicians in the development of effective diagnosis, treatment, case detection, and vector control represents an important example of TDR's stewardship toward the elimination of VL in the Indian subcontinent.
[Mh] Termos MeSH primário: Erradicação de Doenças
Leishmaniose Visceral/epidemiologia
Leishmaniose Visceral/prevenção & controle
Prática de Saúde Pública
Pesquisa Médica Translacional
[Mh] Termos MeSH secundário: Animais
Seres Humanos
Índia/epidemiologia
Controle de Insetos/métodos
Insetos Vetores/parasitologia
Insetos Vetores/fisiologia
Mosquiteiros Tratados com Inseticida
Inseticidas
Leishmaniose Visceral/diagnóstico
Leishmaniose Visceral/tratamento farmacológico
Phlebotomus/parasitologia
Phlebotomus/fisiologia
Organização Mundial da Saúde
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Nm] Nome de substância:
0 (Insecticides)
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171105
[Lr] Data última revisão:
171105
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171013
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pntd.0005889


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[PMID]:28934263
[Au] Autor:Benabid M; Ghrab J; Rhim A; Ben-Romdhane R; Aoun K; Bouratbine A
[Ad] Endereço:Department of Parasitology, Research Lab: LR 11-IPT-06, Pasteur Institute of Tunis, University Tunis El-Manar, Tunis, Tunisia.
[Ti] Título:Temporal dynamics and Leishmania infantum infection prevalence of Phlebotomus perniciosus (Diptera, Phlebotominae) in highly endemic areas of visceral leishmaniasis in Tunisia.
[So] Source:PLoS One;12(9):e0184700, 2017.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Phlebotomus perniciosus is one of the major vectors of Leishmania infantum in the Mediterranean basin. The aim of this work was (i) to provide information about abundance and temporal dynamics of this Larroussius species in a hot spot area of visceral leishmaniasis in Tunisia, (ii) to detect L. infantum DNA in wild caught female sandflies and (iii) to measure Phlebotomus perniciosus infection rate throughout the active season. Sandflies were collected monthly during one year using CDC miniature light-traps in house and in animal shelters. Male specimens were identified at species level according to morphological characters. Female specimens were conserved individually for molecular study. Leishmania infection was tested by kinetoplast DNA real-time PCR and ITS-1 PCR-sequencing. Subsequent sandfly species identification of infected specimens was done by mitochondrial cytochrome b sequencing. In one year period, overall 4,441 specimens (2230 males and 2211 females) were collected. Sandfly activity started in end-April and ended in early-November. Mean sandfly density in house was significantly lower than in animal shelters (51 ± 50 versus 504 ± 460 sandflies /CDC night, p<0.05). However, a higher proportion of females was found in house (58.4% versus 49.2%, p<0.001). Based on species identification of male specimens, Phlebotomus perniciosus was the dominant species (56% of the whole male sandfly fauna, p<0.0001). It showed two peaks of density in the active season, a sharp one in early May and a higher long lasting one from end-July to end-September. DNA was extracted from 190 female specimens randomly sampled and corresponding to 96 specimens from house and 94 from animal shelters. Twenty four female sandfly were infected by Leishmania infantum. All infected specimens were recognized as Phlebotomus perniciosus. Leishmania infantum infection rate in female sandflies was 2.3 fold higher in house than in animal shelters (17.7% versus 7.4%, p<0.05). In house, estimated number of infected specimens was the highest at the end of the active season. Abundance, dynamics of density and Leishmania infantum infection prevalence of Phlebotomus perniciosus in Tunisian hot spot of visceral leishmaniasis highlight the major role of this Phlebotominae species in L. infantum transmission.
[Mh] Termos MeSH primário: Leishmania infantum
Leishmaniose Visceral/epidemiologia
Phlebotomus/parasitologia
[Mh] Termos MeSH secundário: Animais
Citocromos b/genética
DNA de Protozoário
Doenças Endêmicas
Feminino
Habitação
Abrigo para Animais
Leishmania infantum/genética
Leishmaniose Visceral/transmissão
Masculino
Estações do Ano
Fatores de Tempo
Tunísia/epidemiologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (DNA, Protozoan); 9035-37-4 (Cytochromes b)
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171018
[Lr] Data última revisão:
171018
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170922
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0184700


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[PMID]:28873425
[Au] Autor:Chowdhury R; Faria S; Huda MM; Chowdhury V; Maheswary NP; Mondal D; Akhter S; Akter S; Khan RK; Nabi SG; Kroeger A; Argaw D; Alvar J; Dash AP; Banu Q
[Ad] Endereço:National Institute of Preventive and Social Medicine (NIPSOM), Mohakhali, Dhaka, Bangladesh.
[Ti] Título:Control of Phlebotomus argentipes (Diptera: Psychodidae) sand fly in Bangladesh: A cluster randomized controlled trial.
[So] Source:PLoS Negl Trop Dis;11(9):e0005890, 2017 Sep.
[Is] ISSN:1935-2735
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: A number of studies on visceral leishmaniasis (VL) vector control have been conducted during the past decade, sometimes came to very different conclusion. The present study on a large sample investigated different options which are partially unexplored including: (1) indoor residual spraying (IRS) with alpha cypermethrin 5WP; (2) long lasting insecticide impregnated bed-net (LLIN); (3) impregnation of local bed-nets with slow release insecticide K-O TAB 1-2-3 (KOTAB); (4) insecticide spraying in potential breeding sites outside of house using chlorpyrifos 20EC (OUT) and different combinations of the above. METHODS: The study was a cluster randomized controlled trial where 3089 houses from 11 villages were divided into 10 sections, each section with 6 clusters and each cluster having approximately 50 houses. Based on vector density (males plus females) during baseline survey, the 60 clusters were categorized into 3 groups: (1) high, (2) medium and (3) low. Each group had 20 clusters. From these three groups, 6 clusters (about 300 households) were randomly selected for each type of intervention and control arms. Vector density was measured before and 2, 4, 5, 7, 11, 14, 15, 18 and 22 months after intervention using CDC light traps. The impact of interventions was measured by using the difference-in-differences regression model. RESULTS: A total of 17,434 sand flies were collected at baseline and during the surveys conducted over 9 months following the baseline measurements. At baseline, the average P. argentipes density per household was 10.6 (SD = 11.5) in the control arm and 7.3 (SD = 8.46) to 11.5 (SD = 20.2) in intervention arms. The intervention results presented as the range of percent reductions of sand flies (males plus females) and rate ratios in 9 measurements over 22 months. Among single type interventions, the effect of IRS with 2 rounds of spraying (applied by the research team) ranged from 13% to 75% reduction of P. argentipes density compared to the control arm (rate-ratio [RR] ranged from 0.25 to 0.87). LLINs caused a vector reduction of 9% to 78% (RR, 0.22 to 0.91). KOTAB reduced vectors by 4% to 73% (RR, 0.27 to 0.96). The combination of LLIN and OUT led to a vector reduction of 26% to 86% (RR, 0.14 to 0.74). The reduction for the combination of IRS and OUT was 8% to 88% (RR, 0.12 to 0.92). IRS and LLIN combined resulted in a vector reduction of 13% to 85% (RR, 0.15 to 0.77). The IRS and KOTAB combination reduced vector densities by 16% to 86% (RR, 0.14 to 0.84). Some intermediate measurements for KOTAB alone and for IRS plus LLIN; and IRS plus KOTAB were not statistically significant. The bioassays on sprayed surfaces or netting materials showed favourable results (>80% mortality) for 22 months (IRS tested for 12 months). In the KOTAB, a gradual decline was observed after 6 months. CONCLUSIONS: LLIN and OUT was the best combination to reduce VL vector densities for 22 months or longer. Operationally, this is much easier to apply than IRS. A cost analysis of the preferred tools will follow. The relationship between vector density (males plus females) and leishmaniasis incidence should be investigated, and this will require estimates of the Entomological Inoculation Rate.
[Mh] Termos MeSH primário: Controle de Insetos/métodos
Insetos Vetores/crescimento & desenvolvimento
Phlebotomus/crescimento & desenvolvimento
[Mh] Termos MeSH secundário: Adolescente
Adulto
Idoso
Idoso de 80 Anos ou mais
Animais
Bangladesh
Criança
Pré-Escolar
Feminino
Seres Humanos
Lactente
Recém-Nascido
Masculino
Meia-Idade
Densidade Demográfica
Adulto Jovem
[Pt] Tipo de publicação:COMPARATIVE STUDY; JOURNAL ARTICLE; RANDOMIZED CONTROLLED TRIAL
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170925
[Lr] Data última revisão:
170925
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170906
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pntd.0005890


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[PMID]:28806141
[Au] Autor:Abuzaid AA; Abdoon AM; Aldahan MA; Alzahrani AG; Alhakeem RF; Asiri AM; Alzahrani MH; Memish ZA
[Ad] Endereço:1 Infectious Diseases Control Directorate, Ministry of Health , Riyadh, Kingdom of Saudi Arabia .
[Ti] Título:Cutaneous Leishmaniasis in Saudi Arabia: A Comprehensive Overview.
[So] Source:Vector Borne Zoonotic Dis;17(10):673-684, 2017 Oct.
[Is] ISSN:1557-7759
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Despite the great efforts by health authorities in Kingdom of Saudi Arabia (KSA), Cutaneous leishmaniasis (CL) continues to be a major public health problem in the country. Many risk factors make KSA prone to outbreaks and epidemics; among these, rapid urbanization and the huge population movement are the most important. The disease is endemic in many parts of KSA, with the majority of cases concentrated in six regions, including Al-Qaseem, Riyadh, Al-Hassa, Aseer, Ha'il, and Al-Madinah. Leishmania major (L. major) and Leishmania tropica (L. tropica) are the main dermotropic species, and Phlebotomus papatasi (vector of L. major) and Phlebotomus sergenti (vector of L. tropica) are the proved vectors of the disease. Psammomys obesus and Meriones libycus have been defined as the principal reservoir hosts of zoonotic CL in Al-Hassa oasis, Al-Madinah, and Al-Qaseem provinces. Clinically, males are affected more than females, and there is no variation between the Saudis and expatriates in terms of number of reported cases, but the disease tends to run a more severe course among non-Saudis. Face is the most commonly affected site, and ulcerative pattern accounts for 90% of lesions. Despite local and international recommendations of using laboratory diagnostics to confirm CL cases, most cases in KSA are diagnosed and treated on clinical grounds and local epidemiology. However, systemic parenteral sodium stibogluconate (SSG) is the first line of therapy and used to treat all CL patients irrespective of their clinical presentation or the incriminated species. In brief, more efforts are needed to combat this disease. Several aspects of the disease require more evaluation through encouragement of national and regional studies. Development of evidence based national diagnostic and management guidelines, as well as algorithms, is urgently needed to improve the practice of diagnosing and treating CL in KSA.
[Mh] Termos MeSH primário: Leishmaniose Cutânea/epidemiologia
Leishmaniose Cutânea/prevenção & controle
[Mh] Termos MeSH secundário: Animais
Reservatórios de Doenças
Seres Humanos
Insetos Vetores/parasitologia
Leishmania/fisiologia
Phlebotomus/parasitologia
Arábia Saudita/epidemiologia
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171024
[Lr] Data última revisão:
171024
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170815
[St] Status:MEDLINE
[do] DOI:10.1089/vbz.2017.2119


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[PMID]:28719307
[Au] Autor:Jaouadi K; Bettaieb J; Bennour A; Salem S; Rjeibi MR; Chaabane S; Yazidi R; Khabouchi N; Gharbi A; Salah AB
[Ad] Endereço:Laboratory of Medical Epidemiology, Institut Pasteur de Tunis (IPT), Tunis-Belvédère, Tunisia; University Tunis El Manar, Tunisia.
[Ti] Título:First Report on Natural Infection of with in a Classical Focus of in Tunisia.
[So] Source:Am J Trop Med Hyg;97(1):291-294, 2017 Jul.
[Is] ISSN:1476-1645
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:In Tunisia, chronic cutaneous leishmaniasis due to is an important health problem. Its spreading has not been fully elucidated. Information on sandfly vectors, as well as their associated species, is of paramount importance since vector dispersion is one of the major factors responsible for pathogen dissemination. Ninety-seven unfed females belonging to the genera and were collected between June and August 2015 using sticky paper traps. Polymerase chain reaction-restriction fragment length polymorphism analysis of the internal transcribed spacer 1and sequencing were used for detection and identification. In total, 650 sandflies were captured and identified (380 males and 270 females). Ninety-seven unfed females were tested for the presence of parasite DNA. Six were found positive for . This novel finding enhances the understanding of the cycle extension of outside its original focus of Tataouine.
[Mh] Termos MeSH primário: DNA de Protozoário/genética
Leishmania major/fisiologia
Leishmania tropica/fisiologia
Phlebotomus/parasitologia
[Mh] Termos MeSH secundário: Animais
DNA Intergênico/genética
Feminino
Interações Hospedeiro-Parasita
Leishmania major/genética
Leishmania tropica/genética
Filogenia
Tunísia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (DNA, Intergenic); 0 (DNA, Protozoan)
[Em] Mês de entrada:1707
[Cu] Atualização por classe:170731
[Lr] Data última revisão:
170731
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:170719
[St] Status:MEDLINE
[do] DOI:10.4269/ajtmh.16-0849


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[PMID]:28653450
[Au] Autor:Zaidi F; Fatima SH; Jan T; Fatima M; Ali A; Khisroon M; Adnan M; Rasheed SB
[Ad] Endereço:Department of Zoology, University of Peshawar, Pakistan.
[Ti] Título:Environmental risk modelling and potential sand fly vectors of cutaneous leishmaniasis in Chitral district: a leishmanial focal point of mount Tirich Mir, Pakistan.
[So] Source:Trop Med Int Health;22(9):1130-1140, 2017 Sep.
[Is] ISSN:1365-3156
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:OBJECTIVE: To provide baseline information about suspected vectors and the incidence, distribution and an active zone of transmission for cutaneous leishmaniasis (CL) in Chitral, Pakistan, using GIS tools; and to investigate the role of environmental factors in the disease dynamics. METHOD: Two surveys in 2014 and 2016 as a basis for choropleth and environmental risk mapping. RESULTS: A total of 769 captured specimens yielded 14 Phlebotomus and six Sergentomyia species including two potential vectors of CL, i.e. Phlebotomus papatasi and Phlebotomus sergenti. P. papatasi (71%) was dominant, followed by P. sergenti (18%). A choropleth map generated in Arcmap 10.1 based on 1560 CL case reports displayed maximum prevalence (0.92-2.5%) in Ayun, Broz, Charun, Chitral 1 and 2 and Darosh 1 and 2 union councils. An environmental risk map constructed by MaxEnt 3.3.3 defined an active zone of transmission based on leishmaniasis occurrence records (n = 315). The analysis of variable contribution in MaxEnt indicates significance of elevation (54.4%), population density (23.3%) and land use/land cover (6.6%) in CL disease dynamics. CONCLUSION: The probability of CL increases (0.6-1 on logistic scale) in severely deforested areas, in lowland valleys and in regions with high-population density.
[Mh] Termos MeSH primário: Meio Ambiente
Insetos Vetores
Leishmania
Leishmaniose Cutânea/transmissão
Psychodidae/parasitologia
[Mh] Termos MeSH secundário: Altitude
Animais
Conservação dos Recursos Naturais
Feminino
Habitação
Seres Humanos
Leishmaniose Cutânea/epidemiologia
Leishmaniose Cutânea/parasitologia
Masculino
Paquistão/epidemiologia
Phlebotomus
Densidade Demográfica
Risco
Inquéritos e Questionários
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170913
[Lr] Data última revisão:
170913
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170628
[St] Status:MEDLINE
[do] DOI:10.1111/tmi.12916


  10 / 1783 MEDLINE  
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[PMID]:28609907
[Au] Autor:Oca-Aguilar ACM; Mikery-Pacheco O; Castillo A; Rebollar-Téllez EA; Piermarini PM; Ibáñez-Bernal S
[Ad] Endereço:Instituto de Ecología, A.C., Red Ambiente y Sustentabilidad. Carretera Antigua a Coatepec No. 351, El Haya, CP 91070, Xalapa, Veracruz, México.. user@example.com.
[Ti] Título:Morphology variation of Lutzomyia cruciata eggs (Diptera: Psychodidae: Phlebotominae) in southern Mexico.
[So] Source:Zootaxa;4258(5):477-489, 2017 05 02.
[Is] ISSN:1175-5334
[Cp] País de publicação:New Zealand
[La] Idioma:eng
[Ab] Resumo:The sand fly Lutzomyia cruciata has been associated with the transmission of Leishmania mexicana to humans in Mexico. This species has a wide distribution in Mexico occupying different microhabitats and environments. In this work comparisons of the egg exochorion of Lu. cruciata from different physiographic areas are presented. Study sites are from different states of southern Mexico. Exochorion analysis was carried out using scanning electron microscopy (SEM). Results show differences in the exochorionic pattern among samples from Veracruz (AVER), Yucatán (HOYU) and Chiapas (TACH). The morphotype "Chiapas" has a polygonal crest pattern, the morphotype "Veracruz" shows parallel and longitudinal crests with some or few connections, and the morphotype "Yucatán" has weak connections between crest ridges. These morphological differences could be the result of local adaptations or evidence of divergence within the nominal unit Lutzomyia cruciata.
[Mh] Termos MeSH primário: Psychodidae
[Mh] Termos MeSH secundário: Estruturas Animais
Animais
Seres Humanos
Insetos Vetores
México
Phlebotomus
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170809
[Lr] Data última revisão:
170809
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170615
[St] Status:MEDLINE
[do] DOI:10.11646/zootaxa.4258.5.5



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