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Pesquisa : B01.050.500.500.294.400.937.700.722 [Categoria DeCS]
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[PMID]:28407785
[Au] Autor:Cabanová V; Kocák P; Víchová B; Miterpáková M
[Ad] Endereço:Institute of Parasitology, Slovak Academy of Sciences, Hlinkova 3, 040 01, Kosice, Slovakia.
[Ti] Título:First autochthonous cases of canine thelaziosis in Slovakia: a new affected area in Central Europe.
[So] Source:Parasit Vectors;10(1):179, 2017 Apr 13.
[Is] ISSN:1756-3305
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: The spirurid nematode Thelazia callipaeda, also called the "Oriental eyeworm", is the causative agent of canine and human ocular thelaziosis. In the past few years it has started to spread across central Europe and new endemic areas have been established. The present study reports on the first four autochthonous cases of canine ocular thelaziosis in the territory of Slovakia, Central Europe. RESULTS: All cases were recorded in dogs living in eastern Slovakia, near the border with the Ukraine. All worms collected were investigated morphologically and their identification further confirmed at the molecular level by PCR amplification and direct sequencing. Nucleotide sequences of partial T. callipaeda cox1 and 28S rDNA gene fragments isolated from Slovak dogs were submitted to the GenBank database under accession numbers KY476400 and KY476401, respectively. CONCLUSIONS: Considering that all four cases were diagnosed in animals that had never travelled abroad, there is clear evidence of an autochthonous occurrence and thereby the further spread of T. callipaeda across Europe. Moreover, at latitude of 48°N, these cases might be considered as the northernmost recorded cases of autochthonous in western and Central Europe.
[Mh] Termos MeSH primário: Doenças do Cão/parasitologia
Infecções por Spirurida/veterinária
Thelazioidea/isolamento & purificação
[Mh] Termos MeSH secundário: Animais
Análise por Conglomerados
DNA Ribossômico/química
DNA Ribossômico/genética
Doenças do Cão/patologia
Cães
Complexo IV da Cadeia de Transporte de Elétrons/genética
Feminino
Masculino
Microscopia
Filogenia
RNA Ribossômico 28S/genética
Análise de Sequência de DNA
Eslováquia
Infecções por Spirurida/parasitologia
Infecções por Spirurida/patologia
Thelazioidea/anatomia & histologia
Thelazioidea/classificação
Thelazioidea/genética
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Nm] Nome de substância:
0 (DNA, Ribosomal); 0 (RNA, Ribosomal, 28S); EC 1.9.3.1 (Electron Transport Complex IV)
[Em] Mês de entrada:1704
[Cu] Atualização por classe:170425
[Lr] Data última revisão:
170425
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170415
[St] Status:MEDLINE
[do] DOI:10.1186/s13071-017-2128-2


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[PMID]:28215876
[Au] Autor:Aroch I; Arogeti I; Marcovics A; Spiegel Y; Lavy E
[Ad] Endereço:Koret School of Veterinary Medicine, Hebrew University of Jerusalem, P.O. Box 12, Rehovot 761001, Israel. Electronic address: itamar.aroch@mail.huji.ac.il.
[Ti] Título:In vitro lectin binding to the outer surface of Spirocerca lupi at different life-stages.
[So] Source:Vet Parasitol;235:94-99, 2017 Feb 15.
[Is] ISSN:1873-2550
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:Spirocerca lupi is the esophageal nematode of dogs. Early, transient eosinophilia occurs in experimentally infected dogs, but is absent in advanced cases, suggesting that the nematode evades the dog's immune system. Lectins are proteins or glycoproteins of plant or animal origin, binding different saccharides, with varying specificities and avidities, used to characterize surface haptens in plant and animal parasitic helminths. This study investigated the in vitro binding of six lectins (Concanavalin A [ConA], wheat germ agglutinin [WGA], peanut agglutinin [PNA], soybean agglutinin [SBA], Dolichus biflorus agglutinin [DBA] and Ulex earopaeus agglutinin I [UEA]) to the surface of S. lupi nematodes at different life stages, the L2 and L3 larvae (dead and alive) and to dead adult worms, with negative controls, with and without addition of the six respective inhibitory sugar haptens. Con A moderately bound to surfaces of both live and frozen L3, to the stoma and excretory pores of adult worms, and to the outer surface nematode's eggs, within a female worm, but not to L2. PNA bound only to stoma and excretory pores surfaces in both frozen and live L3. WGA bound strongly to the outer surfaces of live and dead L2 and L3, which resulted in molting of live larvae. These results suggest that the nematode's surface content change during its development. Such changes may play roles in the nematode's interactions with the intermediate and definitive hosts' tissues, and in its ability to evade the immune response, its long survival within the host, and even induce neoplastic transformation.
[Mh] Termos MeSH primário: Lectinas/metabolismo
Estágios do Ciclo de Vida
Infecções por Spirurida/veterinária
Thelazioidea
[Mh] Termos MeSH secundário: Animais
Concanavalina A/metabolismo
Cães
Fezes/parasitologia
Feminino
Glicoproteínas/metabolismo
Interações Hospedeiro-Parasita
Larva
Masculino
Óvulo
Aglutinina de Amendoim/metabolismo
Lectinas de Plantas/metabolismo
Proteínas de Soja/metabolismo
Infecções por Spirurida/parasitologia
Thelazioidea/crescimento & desenvolvimento
Thelazioidea/imunologia
Thelazioidea/metabolismo
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Glycoproteins); 0 (Lectins); 0 (Peanut Agglutinin); 0 (Plant Lectins); 0 (Soybean Proteins); 0 (dolichos biflorus agglutinin); 0 (soybean lectin); 11028-71-0 (Concanavalin A)
[Em] Mês de entrada:1707
[Cu] Atualização por classe:170713
[Lr] Data última revisão:
170713
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170221
[St] Status:MEDLINE


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[PMID]:27787220
[Au] Autor:Moravec F; Adlard R
[Ti] Título:Redescription of Rhabdochona papuanensis (Nematoda: Thelazioidea), a parasite of rainbow fishes (Melanotaenia spp.); the first record of the species of Rhabdochona in Australia.
[So] Source:Acta Parasitol;61(4):820-827, 2016 Dec 01.
[Is] ISSN:1896-1851
[Cp] País de publicação:Poland
[La] Idioma:eng
[Ab] Resumo:Numerous specimens of the parasitic nematode Rhabdochona papuanensis Moravec, Riha et Kuchta, 2008 (Spirurida: Rhabdochonidae) were collected from the intestines of the Australian endemic freshwater fish (eastern rainbow fish) Melanotaenia splendida (Peters) (Melanotaeniidae, Atheriniformes) in the Behana Creek, North Queesland during November of 2015. Although many species of Rhabdochona Railliet, 1916 are known to be common parasites of fishes in other continents, the present finding of R. papuanensis represents the first record of the species belonging to this genus from the Australian mainland. Light and scanning electron microscopical examinations of these newly collected specimens made it possible to redescribe in detail this nematode species, originally incompletely described from a congeneric host in Papua New Guinea. Fully developed, filamented eggs of R. papuanensis and the conspecific fourth-stage larva are described for the first time. The present finding of R. papuanensis in M. splendida from Australia represents new host and geographical records.
[Mh] Termos MeSH primário: Doenças dos Peixes/parasitologia
Infecções por Nematoides/veterinária
Thelazioidea/classificação
[Mh] Termos MeSH secundário: Animais
Austrália/epidemiologia
Feminino
Doenças dos Peixes/epidemiologia
Peixes
Masculino
Infecções por Nematoides/epidemiologia
Infecções por Nematoides/parasitologia
Especificidade da Espécie
Thelazioidea/ultraestrutura
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1701
[Cu] Atualização por classe:170117
[Lr] Data última revisão:
170117
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161028
[St] Status:MEDLINE


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[PMID]:27705268
[Au] Autor:Huh K; Choi JH
[Ad] Endereço:Armed Forces Capital Hospital, Gyeonggi-do, South Korea nicedoc2k@gmail.com.
[Ti] Título:Worms in the Eye.
[So] Source:N Engl J Med;375(14):e30, 2016 Oct 06.
[Is] ISSN:1533-4406
[Cp] País de publicação:United States
[La] Idioma:eng
[Mh] Termos MeSH primário: Oftalmopatias/parasitologia
Infecções por Spirurida/parasitologia
Thelazioidea/isolamento & purificação
[Mh] Termos MeSH secundário: Animais
Túnica Conjuntiva/parasitologia
Seres Humanos
Aparelho Lacrimal/parasitologia
Masculino
Adulto Jovem
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Em] Mês de entrada:1701
[Cu] Atualização por classe:170111
[Lr] Data última revisão:
170111
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:161006
[St] Status:MEDLINE


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[PMID]:27523947
[Au] Autor:Otranto D; Colella V; Crescenzo G; Solari Basano F; Nazzari R; Capelli G; Petry G; Schaper R; Pollmeier M; Mallia E; Dantas-Torres F; Lia RP
[Ad] Endereço:Dipartimento di Medicina Veterinaria, Università degli Studi di Bari, 70010 Valenzano, Italy. Electronic address: domenico.otranto@uniba.it.
[Ti] Título:Efficacy of moxidectin 2.5% and imidacloprid 10% in the treatment of ocular thelaziosis by Thelazia callipaeda in naturally infected dogs.
[So] Source:Vet Parasitol;227:118-21, 2016 Aug 30.
[Is] ISSN:1873-2550
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:Thelazia callipaeda (Spirurida, Thelaziidae) has been documented as agent of ocular infection in domestic animals (dogs and cats), wildlife (e.g., foxes, hares, rabbits), and humans. In the last two decades, this parasitosis has been increasingly reported in several European countries. Both adult and larval stages of the eyeworm are responsible for symptoms ranging from mild (e.g., lacrimation, ocular discharge, epiphora) to severe (e.g., conjunctivitis, keratitis, and corneal opacity or ulcers). The present study evaluated the clinical efficacy and safety of imidacloprid 10% and moxidectin 2.5% spot on (Advocate(®), Bayer Animal Health) in comparison to milbemycin oxime/praziquantel tablets (Milbemax(®), Novartis-Animal Health), as positive control, in the treatment of canine thelaziosis in naturally infected dogs and, a third group was used as an untreated control. Forty-seven dogs (27 females and 20 males) harbouring at least one live adult worm of T. callipaeda in one eye were enrolled from an endemic area of southern Italy. Each dog was then weighed and assigned in accordance with a random treatment allocation plan to one of the treatment groups (G1: imidacloprid 10% and moxidectin 2.5% spot on, G2: Untreated control and G3: milbemycin oxime/praziquantel tablets). On Day (D) 7, 14, 28 and 35 dogs were physically examined and the infection level was assessed by examination of both eyes, including conjunctival pouch and third eyelid for live adult T. callipaeda count and clinical scores. Dogs in G1 were treated on D0 and D28, whereas those in G3 on D0 and D7. Efficacy in G1 was 100% at each day post treatment (p<0.01). For the G3 group efficacy was 57.39% on D7 (p<0.05), 92.79% on D14 and 100% on D28 and D35 (p<0.01). The application of the spot on formulation moxidectin 2.5% and imidacloprid 10% was highly effective in the treatment of canine thelaziosis caused by T. callipaeda. Advocate(®) spot on can be recommended for the control of T. callipaeda infection, considering that this formulation is currently licensed in Europe for the treatment of a wide range of parasites affecting dogs.
[Mh] Termos MeSH primário: Doenças do Cão/parasitologia
Oftalmopatias/veterinária
Imidazóis/uso terapêutico
Macrolídeos/uso terapêutico
Nitrocompostos/uso terapêutico
Infecções por Spirurida/veterinária
Thelazioidea/classificação
[Mh] Termos MeSH secundário: Administração Cutânea
Animais
Anti-Helmínticos/administração & dosagem
Anti-Helmínticos/uso terapêutico
Colinérgicos/administração & dosagem
Colinérgicos/uso terapêutico
Doenças do Cão/tratamento farmacológico
Cães
Oftalmopatias/tratamento farmacológico
Oftalmopatias/parasitologia
Feminino
Imidazóis/administração & dosagem
Macrolídeos/administração & dosagem
Masculino
Neonicotinoides
Nitrocompostos/administração & dosagem
Infecções por Spirurida/tratamento farmacológico
Thelazioidea/isolamento & purificação
[Pt] Tipo de publicação:JOURNAL ARTICLE; RANDOMIZED CONTROLLED TRIAL
[Nm] Nome de substância:
0 (Anthelmintics); 0 (Cholinergic Agents); 0 (Imidazoles); 0 (Macrolides); 0 (Neonicotinoids); 0 (Nitro Compounds); 3BN7M937V8 (imidacloprid); 51570-36-6 (milbemycin)
[Em] Mês de entrada:1705
[Cu] Atualização por classe:171116
[Lr] Data última revisão:
171116
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160816
[St] Status:MEDLINE


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[PMID]:27514901
[Au] Autor:Beugnet F; Crafford D; de Vos C; Kok D; Larsen D; Fourie J
[Ad] Endereço:Merial SAS, 29 Avenue Tony Garnier, 67007 Lyon, France.
[Ti] Título:Evaluation of the efficacy of monthly oral administration of afoxolaner plus milbemycin oxime (NexGard Spectra(®), Merial) in the prevention of adult Spirocerca lupi establishment in experimentally infected dogs.
[So] Source:Vet Parasitol;226:150-61, 2016 Aug 15.
[Is] ISSN:1873-2550
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:The nematode Spirocerca lupi (Rudolphi, 1809) is widely distributed but mostly occurs sporadically with stable populations only in certain geographic areas. This helminth mainly infects dogs and wild canids. Primary pathology relates to migration of third stage larvae (L3) damaging the thoracic aorta and establishment of adults in nodules in the oesophagus. The objective of the present study was to evaluate the efficacy of milbemycin oxime in combination with afoxolaner (NexGard Spectra(®), Merial), administered monthly, in preventing establishment of adult worms after experimental infection. Two groups consisting of eight animals each were experimentally infected with 15 L3 on Days -28, -14 and -2, respectively (45 L3 per animal in total). Group 1 dogs served as untreated (negative) control, whereas animals in group 2 were treated with NexGard Spectra(®) at a minimum dose of 0.5mg/kg milbemycin oxime on Day 0 and from then onwards every 28 days up to Day 140 (six treatment occasions). Endoscopy was performed on Day 112 and for some animals also Day 140. Necropsy for worm recovery and nodule/lesion scoring was performed on Day 168. All eight animals in the control group (group 1) presented with 1-3 nodules and worm counts ranging from 9 to 41. Six animals in the NexGard Spectra(®) group presented with 1-4 nodules and worm counts ranging from 1 to 5. Significantly (p<0.05) fewer worms were collected from treated animals in the treated group (geometric mean 1.7) versus the negative control group (geometric mean 22.0) with 92.3% efficacy calculated. There was no significant (p>0.05) difference between groups with reference to number of nodules in the oesophagus. However, nodules in the control group were significantly (p<0.05) larger than those in the treated group. Number and size of lesions in the dorsal aorta did not differ statistically between groups 1 and 2. Because NexGard Spectra(®) was administered 28 days after onset of inoculation, migrating and developing L3 caused damage to the aorta wall of animals in the treated group. Milbemycin oxime (administered as NexGard Spectra(®)) demonstrated effectiveness in reducing infection with adult Spirocerca lupi worms in the oesophagus.
[Mh] Termos MeSH primário: Anti-Helmínticos/administração & dosagem
Doenças do Cão/prevenção & controle
Isoxazóis/administração & dosagem
Macrolídeos/administração & dosagem
Naftalenos/administração & dosagem
Infecções por Spirurida/veterinária
Thelazioidea/efeitos dos fármacos
[Mh] Termos MeSH secundário: Administração Oral
Análise de Variância
Animais
Aorta Torácica/parasitologia
Aorta Torácica/patologia
Autopsia/veterinária
Peso Corporal
Doenças do Cão/tratamento farmacológico
Doenças do Cão/parasitologia
Cães
Esofagoscopia/veterinária
Esôfago/parasitologia
Esôfago/patologia
Fezes/parasitologia
Feminino
Masculino
Contagem de Ovos de Parasitas/veterinária
Infecções por Spirurida/tratamento farmacológico
Infecções por Spirurida/prevenção & controle
[Pt] Tipo de publicação:CONTROLLED CLINICAL TRIAL; JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Anthelmintics); 0 (Isoxazoles); 0 (Macrolides); 0 (Naphthalenes); 02L07H6D0U (afoxolaner); 0502PUN0GT (milbemycin oxime)
[Em] Mês de entrada:1709
[Cu] Atualização por classe:171116
[Lr] Data última revisão:
171116
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160813
[St] Status:MEDLINE


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[PMID]:27417087
[Au] Autor:Yim CH; Ko JH; Lee JH; Choi YM; Lee WW; Ahn SK; Ahn MH; Choi KE
[Ad] Endereço:Department of Pediatrics, Gwangmyeong Sungae Hospital, Gwangmyeong 14241, Korea.
[Ti] Título:A Pediatric Case of Thelaziasis in Korea.
[So] Source:Korean J Parasitol;54(3):319-21, 2016 Jun.
[Is] ISSN:1738-0006
[Cp] País de publicação:Korea (South)
[La] Idioma:eng
[Ab] Resumo:In the present study, we intended to report a clinical pediatric case of thelaziasis in Korea. In addition, we briefly reviewed the literature on pediatric cases of thelaziasis in Korea. In the present case, 3 whitish, thread-like eye-worms were detected in a 6-year-old-boy living in an urban area and contracted an ocular infection known as thelaziasis incidentally during ecological agritainment. This is the first report of pediatric thelaziasis in Seoul after 1995.
[Mh] Termos MeSH primário: Oftalmopatias/diagnóstico
Oftalmopatias/patologia
Infecções por Spirurida/diagnóstico
Infecções por Spirurida/patologia
Thelazioidea/isolamento & purificação
[Mh] Termos MeSH secundário: Animais
Criança
Oftalmopatias/parasitologia
Seres Humanos
Masculino
Microscopia
Parasitologia
República da Coreia
Infecções por Spirurida/parasitologia
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Em] Mês de entrada:1704
[Cu] Atualização por classe:170404
[Lr] Data última revisão:
170404
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160716
[St] Status:MEDLINE
[do] DOI:10.3347/kjp.2016.54.3.319


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[PMID]:27389755
[Au] Autor:Graham-Brown J; Gilmore P; Williams D; Barber J; Andrews M; Timofte D
[Ad] Endereço:Liverpool Veterinary Parasitology Diagnostics, University of Liverpool, Liverpool Science Park IC2, 146 Brownlow Hill, Liverpool L3 5RF, e-mail: J.Graham-Brown@liverpool.ac.uk.
[Ti] Título:Case of canine ocular thelaziosis in the UK.
[So] Source:Vet Rec;179(2):51, 2016 Jul 09.
[Is] ISSN:2042-7670
[Cp] País de publicação:England
[La] Idioma:eng
[Mh] Termos MeSH primário: Doenças do Cão/diagnóstico
Oftalmopatias/veterinária
Infecções por Spirurida/veterinária
Thelazioidea/isolamento & purificação
[Mh] Termos MeSH secundário: Animais
Doenças do Cão/parasitologia
Cães
Oftalmopatias/diagnóstico
Oftalmopatias/parasitologia
Masculino
Infecções por Spirurida/diagnóstico
Reino Unido
[Pt] Tipo de publicação:CASE REPORTS; LETTER
[Em] Mês de entrada:1704
[Cu] Atualização por classe:170817
[Lr] Data última revisão:
170817
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160709
[St] Status:MEDLINE
[do] DOI:10.1136/vr.i3743


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[PMID]:27316971
[Au] Autor:Mihalca AD; Ionica AM; D'Amico G; Daskalaki AA; Deak G; Matei IA; Șimonca V; Iordache D; Modrý D; Gherman CM
[Ad] Endereço:Department of Parasitology and Parasitic Diseases, University of Agricultural Sciences and Veterinary Medicine of Cluj-Napoca, Calea ManaÈ™tur 3-5, Cluj-Napoca, 400372, Romania.
[Ti] Título:Thelazia callipaeda in wild carnivores from Romania: new host and geographical records.
[So] Source:Parasit Vectors;9(1):350, 2016 06 18.
[Is] ISSN:1756-3305
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Thelazia callipaeda is a vector-borne zoonotic nematode parasitizing the conjunctival sac of domestic and wild carnivores, rabbits and humans, with a vast distribution in Asia and the former Soviet Union. In Europe, the nematode has an emerging trend, being reported in Italy, France, Switzerland, Germany, Spain, Portugal, Bosnia and Herzegovina, Croatia, Romania, Greece and Serbia, with human cases known in Italy, France, Spain, Serbia and Croatia. In Romania, the infection was so far reported only in dogs, whereas there are no reports in wildlife despite the large numbers of wild carnivores in the country. The aim of this study was to evaluate the role of wild carnivores in the natural cycle of T. callipaeda in Romania. METHODS: Between 2014 and 2016, 89 wild carnivores (64 golden jackals, Canis aureus, 13 grey wolves, Canis lupus, nine wildcats, Felis silvestris and three Eurasian lynxes, Lynx lynx) have been examined. During the necropsy, both eyes of all the examined animals have been thoroughly inspected for the presence of parasites. If present, all nematodes were collected in absolute ethanol (for molecular analysis of the partial cox1 gene) or in 4 % formalin (for morphological identification). RESULTS: In total, three animals were found to be infected with T. callipaeda: a grey wolf, a golden jackal and a wildcat. The BLAST analysis of all the sequences showed a 100 % similarity to T. callipaeda haplotype h1. To the best of our knowledge, this study represents the first report of T. callipaeda in golden jackals, and the first study on T. callipaeda in wildlife from Romania. CONCLUSION: Our data broaden the host spectrum and geographical distribution of T. callipaeda, highlighting the role of wild carnivores as natural reservoirs for the infection and confirming the ongoing expanding trend of this zoonotic nematode in Europe.
[Mh] Termos MeSH primário: Carnívoros/parasitologia
Infecções por Spirurida/veterinária
Thelazioidea/isolamento & purificação
[Mh] Termos MeSH secundário: Animais
Romênia/epidemiologia
Infecções por Spirurida/epidemiologia
Infecções por Spirurida/parasitologia
Thelazioidea/classificação
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Em] Mês de entrada:1702
[Cu] Atualização por classe:170221
[Lr] Data última revisão:
170221
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160619
[St] Status:MEDLINE
[do] DOI:10.1186/s13071-016-1628-9


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[PMID]:27160400
[Au] Autor:Gama A; Pires I; Canado M; Coutinho T; Lopes AP; Latrofa MS; Cardoso L; Dantas-Torres F; Otranto D
[Ad] Endereço:Department of Veterinary Sciences, Laboratory of Histology and Pathology, School of Agrarian and Veterinary Sciences, University of Trás-os-Montes e Alto Douro (UTAD), Vila Real, Portugal.
[Ti] Título:First report of Thelazia callipaeda infection in wild European rabbits (Oryctolagus cuniculus) in Portugal.
[So] Source:Parasit Vectors;9(1):236, 2016 05 10.
[Is] ISSN:1756-3305
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Thelazia callipaeda is a zoonotic nematode that affects the eyes of domestic and wild animals, including dogs, cats and red foxes. This parasitic eye worm is transmitted by Phortica variegata, which is a zoophilic fruit fly spread in Europe. Two wild European rabbits (Oryctolagus cuniculus) found dead in north-eastern Portugal were submitted to necropsy. RESULTS: Both animals presented gross lesions compatible with haemorrhagic viral disease. Eye examination revealed the presence of six worms (three in each animal, on both eyes). Out of the six nematodes, five females and one male were morphologically and molecularly identified as T. callipaeda. CONCLUSIONS: This is the first report of T. callipaeda in wild rabbits from Portugal, which reveals a new host for this parasite in southern Europe and emphasizes the importance of including thelaziosis in the differential diagnosis of ocular alterations in both animals and humans from areas where the eye worm is endemic.
[Mh] Termos MeSH primário: Drosophilidae/parasitologia
Infecções Oculares Parasitárias/veterinária
Insetos Vetores/parasitologia
Coelhos/parasitologia
Infecções por Spirurida/veterinária
Thelazioidea/isolamento & purificação
[Mh] Termos MeSH secundário: Animais
Animais Selvagens
Diagnóstico Diferencial
Olho/parasitologia
Infecções Oculares Parasitárias/diagnóstico
Infecções Oculares Parasitárias/parasitologia
Evolução Fatal
Feminino
Masculino
Portugal
Infecções por Spirurida/diagnóstico
Infecções por Spirurida/parasitologia
Thelazioidea/classificação
Thelazioidea/citologia
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Em] Mês de entrada:1705
[Cu] Atualização por classe:170522
[Lr] Data última revisão:
170522
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160511
[St] Status:MEDLINE
[do] DOI:10.1186/s13071-016-1526-1



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