Base de dados : MEDLINE
Pesquisa : B01.050.500.500.736.715.770 [Categoria DeCS]
Referências encontradas : 247 [refinar]
Mostrando: 1 .. 10   no formato [Detalhado]

página 1 de 25 ir para página                         

  1 / 247 MEDLINE  
              next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28296924
[Au] Autor:Rimnácová J; Mikes L; Turjanicová L; Bulantová J; Horák P
[Ad] Endereço:Department of Parasitology, Faculty of Science, Charles University, Vinicná 7, Prague 2, Czech Republic.
[Ti] Título:Changes in surface glycosylation and glycocalyx shedding in Trichobilharzia regenti (Schistosomatidae) during the transformation of cercaria to schistosomulum.
[So] Source:PLoS One;12(3):e0173217, 2017.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:The invasive larvae (cercariae) of schistosomes penetrate the skin of their definitive hosts. During the invasion, they undergo dramatic ultrastructural and physiological transitions. These changes result in the development of the subsequent stage, schistosomulum, which migrates through host tissues in close contact with host's immune system. One of the striking changes in the transforming cercariae is the shedding of their thick tegumental glycocalyx, which represents an immunoattractive structure; therefore its removal helps cercariae to avoid immune attack. A set of commercial fluorescently labeled lectin probes, their saccharide inhibitors and monoclonal antibodies against the trisaccharide Lewis-X antigen (LeX, CD15) were used to characterize changes in the surface saccharide composition of the neuropathogenic avian schistosome Trichobilharzia regenti during the transformation of cercariae to schistosomula, both in vitro and in vivo. The effect of various lectins on glycocalyx shedding was evaluated microscopically. The involvement of peptidases and their inhibitors on the shedding of glycocalyx was investigated using T. regenti recombinant cathepsin B2 and a set of peptidase inhibitors. The surface glycocalyx of T. regenti cercariae was rich in fucose and mannose/glucose residues. After the transformation of cercariae in vitro or in vivo within their specific duck host, reduction and vanishing of these epitopes was observed, and galactose/N-acetylgalactosamine emerged. The presence of LeX was not observed on the cercariae, but the antigen was gradually expressed from the anterior part of the body in the developing schistosomula. Some lectins which bind to the cercarial surface also induced secretion from the acetabular penetration glands. Seven lectins induced the shedding of glycocalyx by cercariae, among which five bound strongly to cercarial surface; the effect could be blocked by saccharide inhibitors. Mannose-binding protein, part of the lectin pathway of the complement system, also bound to cercariae and schistosomula, but had little effect on glycocalyx shedding. Our study did not confirm the involvement of proteolysis in glycocalyx shedding.
[Mh] Termos MeSH primário: Glicocálix/metabolismo
Schistosomatidae/metabolismo
[Mh] Termos MeSH secundário: Animais
Glicosilação
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170908
[Lr] Data última revisão:
170908
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170316
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0173217


  2 / 247 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28112601
[Au] Autor:Caron Y; Cabaraux A; Marechal F; Losson B
[Ad] Endereço:1 Research Unit in Parasitology and Parasitic Diseases, Fundamental and Applied Research for Animals & Health (FARAH), Faculty of Veterinary Medicine, University of Liège , Liège, Belgium .
[Ti] Título:Swimmer's Itch in Belgium: First Recorded Outbreaks, Molecular Identification of the Parasite Species and Intermediate Hosts.
[So] Source:Vector Borne Zoonotic Dis;17(3):190-194, 2017 Mar.
[Is] ISSN:1557-7759
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Cercarial dermatitis or swimmer's itch is a skin condition in humans due to the larval forms of bird schistosomes of some species of the genus Trichobilharzia. The life cycle of these schistosomes requires freshwater snails (intermediate host) and waterfowl (definitive host). Repeated exposures to cercariae can lead to skin sensitization with the induction of pruritic skin lesions. METHODS: We describe, in this study, two outbreaks of human cercarial dermatitis at the Eau d'Heure Lakes, Belgium. In July and August 2012, a total of, respectively, 78 and 10 people reported a sudden skin rash accompanied by pruritus following recreational activities in the Plate Taille Lake. However, no ocellate furcocercariae were detected following light exposure of the snails collected between September 2012 and September 2013 (n = 402). No outbreaks were recorded in 2013 and 2014. In August 2015, about 30 new cases were recorded. Snails were collected (n = 270) in different locations around the lake. PCR was used to identify accurately the intermediate hosts and the parasite species involved. RESULTS: After light exposure, seven Radix spp. (2.6%) shed ocellate furcocercariae. Molecular identification based on the rDNA internal transcribed spacer 2 sequence ascribed the infected snails to R. balthica ( = R. peregra = R. ovata) (6/7) and R. auricularia (1/7). Based on the amplification of the D2 domain of the 28S rDNA, the cercariae were shown to belong to two different haplotypes of Trichobilharzia franki. CONCLUSIONS: This is the first record in Belgium of T. franki and associated skin condition.
[Mh] Termos MeSH primário: Dermatite/epidemiologia
Dermatite/parasitologia
Schistosomatidae
Infecções por Trematódeos/epidemiologia
Infecções por Trematódeos/parasitologia
[Mh] Termos MeSH secundário: Animais
Bélgica/epidemiologia
Surtos de Doenças
Seres Humanos
Caramujos/parasitologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170801
[Lr] Data última revisão:
170801
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170124
[St] Status:MEDLINE
[do] DOI:10.1089/vbz.2016.2034


  3 / 247 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28012027
[Au] Autor:Prüter H; Sitko J; Krone O
[Ad] Endereço:Department of Wildlife Diseases, Leibniz Institute for Zoo and Wildlife Research, Alfred-Kowalke-Straße 17, 10315, Berlin, Germany. prueter@izw-berlin.de.
[Ti] Título:Having bird schistosomes in mind-the first detection of Bilharziella polonica (Kowalewski 1895) in the bird neural system.
[So] Source:Parasitol Res;116(3):865-870, 2017 Mar.
[Is] ISSN:1432-1955
[Cp] País de publicação:Germany
[La] Idioma:eng
[Ab] Resumo:Nasal bird schistosomes can cause bilharziosis in birds and have the potential to cause swimmer's itch in humans. We determined the prevalence of bird schistosomes in 106 mallards (Anas plathyrhynchos) from 11 water sources in Germany from 2014. Dissections were performed focusing on parasitic infections of the neural system. Infections with Trichobilharzia regenti (Horák et al. 1998) were found in 21% of the birds (n = 22), whereas Bilharziella polonica (Kowalewski 1895) were found between the brain membranes (meninges) and the brain, in the spinal cord or in the intestine of 12% of the mallards (n = 13). No significant influence of sex, age, and body condition between infected and non-infected animals was observed. Our study provides the first description of B. polonica from the neural system of birds and provides an epidemiological understanding of a parasite of human health concern.
[Mh] Termos MeSH primário: Doenças das Aves/parasitologia
Patos/parasitologia
Sistema Nervoso/parasitologia
Schistosoma/isolamento & purificação
Schistosomatidae/isolamento & purificação
Infecções por Trematódeos/veterinária
[Mh] Termos MeSH secundário: Animais
Animais Selvagens/parasitologia
Alemanha
Seres Humanos
Schistosoma/genética
Schistosoma/fisiologia
Schistosomatidae/genética
Schistosomatidae/fisiologia
Infecções por Trematódeos/parasitologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1706
[Cu] Atualização por classe:171007
[Lr] Data última revisão:
171007
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161225
[St] Status:MEDLINE
[do] DOI:10.1007/s00436-016-5359-9


  4 / 247 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:27611734
[Au] Autor:Brant SV; Loker ES; Casalins L; Flores V
[Ad] Endereço:University of New Mexico, Museum of Southwestern Biology, Center for Evolutionary and Theoretical Immunology, 1 University of New Mexico, MSC03 2020 Department of Biology, Albuquerque, New Mexico 87131.
[Ti] Título:Phylogenetic Placement of a Schistosome from an Unusual Marine Snail Host, the False Limpet (Siphonaria lessoni) and Gulls (Larus dominicanus) from Argentina with a Brief Review of Marine Schistosomes from Snails.
[So] Source:J Parasitol;103(1):75-82, 2017 Feb.
[Is] ISSN:1937-2345
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:In the blood fluke family Schistosomatidae, marine snails are well known as intermediate hosts. Eight families of marine snails have thus far been reported to host schistosomes across the world, most of which have been implicated in human cercarial dermatitis (HCD) outbreaks. As part of our larger effort to define the species diversity and biology of schistosomes in Argentina, in particular their role in causing HCD, we searched in the marine pulmonate snail (Siphonaria lessoni) for a schistosome species described previously from S. lessoni from southern Argentina. Additionally, gulls (Larus dominicanus) collected from a different project locality (inland) were examined, because they are known to spend time in the intertidal regions. Schistosome sporocysts were found in S. lessoni, and a small worm fragment was retrieved from a gull. Molecular phylogenies for 28S, ITS1-5.8S-ITS2, and cox1 genes revealed that the specimens from the gull and S. lessoni grouped closely together, suggesting they are conspecifics. Also, ITS1-5.8S-ITS2 sequences suggested one of the schistosomes from S. lessoni and a schistosome from a South African penguin were also conspecifics. Further study is needed to verify if these specimens comprise a distinct marine clade within the larger avian schistosome clade that is comprised mostly of species using freshwater snail hosts. Thus far, it appears this group of marine schistosomes may be more likely found in the southern hemisphere. It is unclear if the observed distribution pattern of schistosomes in Siphonaria is a result of sampling bias and/or indicative of a specific bird-snail-schistosome association. It is clear they are sharply differentiated from the basal marine clade of avian schistosomes that includes Austrobilharzia.
[Mh] Termos MeSH primário: Doenças das Aves/parasitologia
Charadriiformes/parasitologia
Filogenia
Schistosomatidae/classificação
Caramujos/parasitologia
Infecções por Trematódeos/veterinária
[Mh] Termos MeSH secundário: Animais
Argentina
Teorema de Bayes
Biodiversidade
DNA de Helmintos/química
DNA de Helmintos/isolamento & purificação
DNA Mitocondrial/genética
DNA Ribossômico/química
DNA Espaçador Ribossômico/química
Complexo IV da Cadeia de Transporte de Elétrons/genética
Lagos
Fígado/parasitologia
Veia Porta/parasitologia
RNA Ribossômico 28S/genética
RNA Ribossômico 5,8S/genética
Schistosomatidae/genética
Schistosomatidae/isolamento & purificação
Infecções por Trematódeos/parasitologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (DNA, Helminth); 0 (DNA, Mitochondrial); 0 (DNA, Ribosomal); 0 (DNA, Ribosomal Spacer); 0 (RNA, Ribosomal, 28S); 0 (RNA, Ribosomal, 5.8S); EC 1.9.3.1 (Electron Transport Complex IV)
[Em] Mês de entrada:1705
[Cu] Atualização por classe:170531
[Lr] Data última revisão:
170531
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160910
[St] Status:MEDLINE
[do] DOI:10.1645/16-43


  5 / 247 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
[PMID]:27842570
[Au] Autor:Machácek T; Panská L; Dvoráková H; Horák P
[Ad] Endereço:Department of Parasitology, Faculty of Science, Charles University, Vinicná 7, Prague 2, 12844, Czech Republic. tomas.machacek@natur.cuni.cz.
[Ti] Título:Nitric oxide and cytokine production by glial cells exposed in vitro to neuropathogenic schistosome Trichobilharzia regenti.
[So] Source:Parasit Vectors;9(1):579, 2016 Nov 14.
[Is] ISSN:1756-3305
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Helminth neuroinfections represent a serious health problem, but host immune mechanisms in the nervous tissue often remain undiscovered. This study aims at in vitro characterization of the response of murine astrocytes and microglia exposed to Trichobilharzia regenti which is a neuropathogenic schistosome migrating through the central nervous system of vertebrate hosts. Trichobilharzia regenti infects birds and mammals in which it may cause severe neuromotor impairment. This study was focused on astrocytes and microglia as these are immunocompetent cells of the nervous tissue and their activation was recently observed in T. regenti-infected mice. RESULTS: Primary astrocytes and microglia were exposed to several stimulants of T. regenti origin. Living schistosomulum-like stages caused increased secretion of IL-6 in astrocyte cultures, but no changes in nitric oxide (NO) production were noticed. Nevertheless, elevated parasite mortality was observed in these cultures. Soluble fraction of the homogenate from schistosomulum-like stages stimulated NO production by both astrocytes and microglia, and IL-6 and TNF-α secretion in astrocyte cultures. Similarly, recombinant cathepsins B1.1 and B2 triggered IL-6 and TNF-α release in astrocyte and microglia cultures, and NO production in astrocyte cultures. Stimulants had no effect on production of anti-inflammatory cytokines IL-10 or TGF-ß1. CONCLUSIONS: Both astrocytes and microglia are capable of production of NO and proinflammatory cytokines IL-6 and TNF-α following in vitro exposure to various stimulants of T. regenti origin. Astrocytes might be involved in triggering the tissue inflammation in the early phase of T. regenti infection and are proposed to participate in destruction of migrating schistosomula. However, NO is not the major factor responsible for parasite damage. Both astrocytes and microglia can be responsible for the nervous tissue pathology and maintaining the ongoing inflammation since they are a source of NO and proinflammatory cytokines which are released after exposure to parasite antigens.
[Mh] Termos MeSH primário: Interleucina-6/metabolismo
Neuroglia/imunologia
Neuroglia/parasitologia
Óxido Nítrico/metabolismo
Schistosomatidae/imunologia
Fator de Necrose Tumoral alfa/metabolismo
[Mh] Termos MeSH secundário: Animais
Astrócitos/imunologia
Astrócitos/parasitologia
Células Cultivadas
Camundongos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Interleukin-6); 0 (Tumor Necrosis Factor-alpha); 0 (interleukin-6, mouse); 31C4KY9ESH (Nitric Oxide)
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170926
[Lr] Data última revisão:
170926
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161116
[St] Status:MEDLINE


  6 / 247 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:27394285
[Au] Autor:Aldhoun J; Kment P; Horák P
[Ad] Endereço:Parasites & Vectors, Department of Life Sciences, Natural History Museum, Cromwell Road, SW7 5BD, London, United Kingdom.; Email: j.aldhoun@gmail.com.
[Ti] Título:Historical analysis of the type species of the genus Trichobilharzia Skrjabin et Zakharov, 1920 (Platyhelminthes: Schistosomatidae).
[So] Source:Zootaxa;4084(4):593-5, 2016 Feb 29.
[Is] ISSN:1175-5334
[Cp] País de publicação:New Zealand
[La] Idioma:eng
[Ab] Resumo:Trichobilharzia Skrjabin & Zakharov, 1920 is known as the most species-rich genus of the blood fluke family Schistosomatidae. To date, more than 40 species have been described, even though validity of some of them is questionable (Horák et al. 2002). Members of the genus use various birds as final hosts, but they attract attention mostly as causative agents of hypersensitive skin reaction (cercarial dermatitis or swimmer's itch) in mammals including humans. As this is one of the.
[Mh] Termos MeSH primário: Doenças das Aves/parasitologia
Schistosomatidae/classificação
Dermatopatias Parasitárias/parasitologia
[Mh] Termos MeSH secundário: Estruturas Animais/anatomia & histologia
Estruturas Animais/crescimento & desenvolvimento
Animais
Doenças das Aves/história
Aves
História do Século XIX
História do Século XX
Seres Humanos
Tamanho do Órgão
Parasitologia/história
Schistosomatidae/isolamento & purificação
Schistosomatidae/fisiologia
Dermatopatias Parasitárias/história
[Pt] Tipo de publicação:HISTORICAL ARTICLE; JOURNAL ARTICLE
[Em] Mês de entrada:1702
[Cu] Atualização por classe:170209
[Lr] Data última revisão:
170209
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160711
[St] Status:MEDLINE
[do] DOI:10.11646/zootaxa.4084.4.10


  7 / 247 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:27260861
[Au] Autor:Ebbs ET; Loker ES; Davis NE; Flores V; Veleizan A; Brant SV
[Ad] Endereço:Department of Biology, Museum of Southwestern Biology Parasite Division, Center for Evolutionary and Theoretical Immunology, University of New Mexico, 167 Castetter MSCO3 2020, Albuquerque, NM 87131, USA. Electronic address: gendron@unm.edu.
[Ti] Título:Schistosomes with wings: how host phylogeny and ecology shape the global distribution of Trichobilharzia querquedulae (Schistosomatidae).
[So] Source:Int J Parasitol;46(10):669-77, 2016 Sep.
[Is] ISSN:1879-0135
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Migratory waterfowl play an important role in the maintenance and spread of zoonotic diseases worldwide. An example is cercarial dermatitis, caused when larval stages of schistosomes that normally develop in birds penetrate human skin. Members of the genus Trichobilharzia (Schistosomatidae), transmitted mainly by ducks, are considered to be major etiological agents of cercarial dermatitis globally. To better understand the diversity and distribution of Trichobilharzia spp., we surveyed ducks from the United States, eastern Canada, Argentina, South Africa and New Zealand. To aid in species identification of the Trichobilharzia worms recovered, regions of the Cox1, ND4 and ITS1 were sequenced. Furthermore, we provide molecular phylogenetic evidence for the cosmopolitan distribution and trans-hemispheric gene flow for one species, Trichobilharzia querquedulae, previously thought to be restricted to North America. These new samples from endemic non-migratory duck species indicate that T. querquedulae transmission occurs within each of the regions we sampled and that it is specific to the blue-winged+silver teal duck clade. Prevalence within this host group is >95% across the known range of T. querquedulae, indicating that transmission is common. Genetic divergence is evenly distributed among continents, and no phylogenetic structure associated with geography was observed. The results provide strong support for the global distribution and transmission of T. querquedulae and represent, to our knowledge, the first report of a cosmopolitan schistosome confirmed by genetic data. These data are the first known to support trans-hemispheric genetic exchange in a species responsible for causing cercarial dermatitis, indicating that the epidemiology of this group of poorly known zoonotic parasites is more complex than previously expected.
[Mh] Termos MeSH primário: Doenças das Aves/epidemiologia
Patos/parasitologia
Gansos/parasitologia
Schistosomatidae/classificação
Infecções por Trematódeos/veterinária
[Mh] Termos MeSH secundário: Animais
Animais Selvagens
Teorema de Bayes
Doenças das Aves/parasitologia
DNA Intergênico/genética
Ecologia
Complexo IV da Cadeia de Transporte de Elétrons/genética
Genes Mitocondriais
Funções Verossimilhança
NADH Desidrogenase/genética
Filogenia
Prevalência
Schistosomatidae/genética
Schistosomatidae/fisiologia
Caramujos/parasitologia
Infecções por Trematódeos/epidemiologia
Infecções por Trematódeos/parasitologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (DNA, Intergenic); EC 1.6.99.3 (NADH Dehydrogenase); EC 1.9.3.1 (Electron Transport Complex IV)
[Em] Mês de entrada:1706
[Cu] Atualização por classe:170630
[Lr] Data última revisão:
170630
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160605
[St] Status:MEDLINE


  8 / 247 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:27208886
[Au] Autor:Yong RQ; Cutmore SC; Bray RA; Miller TL; Semarariana IW; Palm HW; Cribb TH
[Ad] Endereço:School of Biological Sciences, The University of Queensland, Brisbane, Queensland 4072, Australia. Electronic address: rqy.yong@uqconnect.edu.au.
[Ti] Título:Three new species of blood flukes (Digenea: Aporocotylidae) infecting pufferfishes (Teleostei: Tetraodontidae) from off Bali, Indonesia.
[So] Source:Parasitol Int;65(5 Pt A):432-43, 2016 Oct.
[Is] ISSN:1873-0329
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:We describe three new species of blood flukes (Aporocotylidae) and propose their classification within the genus Psettarium Goto & Ozaki, 1929. All three species were collected from the circulatory systems of pufferfishes caught off Bali, central Indonesia. Psettarium pulchellum n. sp. was found in the gills of both the narrow-lined puffer (Arothron manilensis de Procé) and the spiny blaasop (Tylerius spinosissimus Regan), while P. ogawai n. sp. and P. jimbaranense n. sp. were found in the gills of the reticulated puffer (Arothron reticularis Bloch & Schneider). The morphological characteristics of these taxa necessitated emendation of the diagnosis for the genus Psettarium, to accommodate the presence of an oral sucker, multiple or entirely post-caecal testes and a degenerate posterior testis. Features such as proportion of body length occupied by the oesophagus, and posterior caeca being ≥7× the length of anterior caeca, are no longer regarded as useful genus-level characters. Additionally, Sasala nolani is reassigned to this genus as Psettarium nolani n. comb. In phylogenetic analyses of the 28S and ITS2 rDNA regions, all three new taxa form a well-supported clade, together with Psettarium sinense and Psettarium nolani n. comb., the two other species of tetraodontid-infecting aporocotylids for which comparative rDNA data were available. The short branch lengths within this clade, despite dramatic morphological differences between the five species, suggest that rapid morphological diversification has occurred among the tetraodontid-infecting aporocotylids. The genus Psettarium has long been considered problematic. Further commentary is given on the history of this genus and how the issues presented might be resolved.
[Mh] Termos MeSH primário: Doenças dos Peixes/parasitologia
Schistosomatidae/classificação
Schistosomatidae/genética
Tetraodontiformes/parasitologia
Infecções por Trematódeos/veterinária
[Mh] Termos MeSH secundário: Animais
DNA Espaçador Ribossômico/genética
Feminino
Indonésia
Masculino
Tipagem Molecular
Filogenia
RNA Ribossômico 28S/genética
Schistosomatidae/anatomia & histologia
Schistosomatidae/isolamento & purificação
Infecções por Trematódeos/parasitologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (DNA, Ribosomal Spacer); 0 (RNA, Ribosomal, 28S)
[Em] Mês de entrada:1703
[Cu] Atualização por classe:170313
[Lr] Data última revisão:
170313
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160522
[St] Status:MEDLINE


  9 / 247 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:27185234
[Au] Autor:Nolan MJ; Cantacessi C; Cutmore SC; Cribb TH; Miller TL
[Ad] Endereço:Department of Pathology and Pathogen Biology, Royal Veterinary College, University of London, North Mymms, Hatfield AL9 7TA, United Kingdom. Electronic address: mnolan@rvc.ac.uk.
[Ti] Título:High-intensity cardiac infections of Phthinomita heinigerae n. sp. (Digenea: Aporocotylidae) in the orangelined cardinalfish, Taeniamia fucata (Cantor), off Heron Island on the Great Barrier Reef.
[So] Source:Parasitol Int;65(5 Pt A):371-7, 2016 Oct.
[Is] ISSN:1873-0329
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:We report a new species of aporocotylid trematode (Platyhelminthes: Digenea) from the heart of the orangelined cardinalfish, Taeniamia fucata (Cantor), from off Heron Island on the southern Great Barrier Reef. We used an integrated approach, analysing host distribution, morphology, and genetic data from the internal transcribed spacer 2 of the ribosomal DNA, to circumscribe Phthinomita heinigerae n. sp. This is the first species of Phthinomita Nolan & Cribb, 2006 reported from the Apogonidae; existing species and known 'types' are recorded from species of the Labridae, Mullidae, and Siganidae. The new species is distinguished from its 11 congeners in having a body 2977-3539 long and 16.5-22.4 times longer than wide, an anterior testis 6.2-8.2 times longer than wide and 8.3-13.0 times longer than the posterior testis, a posterior testis whose width is 35-56% of the body width, and an ovary positioned 11-13% of the body length from the posterior end, and is entirely anterior to the posterior margin of the anterior testis. In addition, 2-34 base differences (0.4-7.0% sequence divergence over 485 base positions) were detected among the ITS2 sequence representing P. heinigerae n. sp. and the 14 representing other Phthinomita species/molecular types. Prevalence and intensity of infection with P. heinigerae n. sp. was relatively high within the heart tissue of T. fucata, with 19 of 20 fish examined from off Heron Island infected (95%) with 7-25 adult worms (arithmetic mean 16.6). Infections by these parasites accounted for an occupation of 7-30% of the total estimated heart volume.
[Mh] Termos MeSH primário: Doenças dos Peixes/parasitologia
Cardiopatias/parasitologia
Coração/parasitologia
Perciformes/parasitologia
Schistosomatidae/genética
Infecções por Trematódeos/veterinária
[Mh] Termos MeSH secundário: Animais
Austrália
Sequência de Bases
DNA de Helmintos/genética
DNA Espaçador Ribossômico/genética
Feminino
Cardiopatias/veterinária
Especificidade de Hospedeiro
Masculino
Schistosomatidae/classificação
Análise de Sequência de DNA
Infecções por Trematódeos/parasitologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (DNA, Helminth); 0 (DNA, Ribosomal Spacer)
[Em] Mês de entrada:1703
[Cu] Atualização por classe:170313
[Lr] Data última revisão:
170313
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160518
[St] Status:MEDLINE


  10 / 247 MEDLINE  
              first record previous record
seleciona
para imprimir
Fotocópia
[PMID]:27085007
[Au] Autor:Chanová M; Hrdý J
[Ad] Endereço:Institute of Immunology and Microbiology of the First Faculty of Medicine, Charles University in Prague and General University Hospital in Prague, Czech Republic.
[Ti] Título:Impact of Induced Th1/Th2 Shift on Trichobilharzia regenti Infection in Mice.
[So] Source:Folia Biol (Praha);62(1):26-33, 2016.
[Is] ISSN:0015-5500
[Cp] País de publicação:Czech Republic
[La] Idioma:eng
[Ab] Resumo:Bird schistosomes parasitize mammals as non-specific hosts. Neurotropic Trichobilharzia regenti migrates extravasally via nervous tissue in experimentally infected mice. The majority of successfully penetrated larvae remain in the skin; the rest migrate through peripheral nerves to the spinal cord and brain. The potential of schistosomula to leave the skin and enter the central nervous system vary, and may be associated with Th1/Th2 polarization of the host cell immune response. The aim of the present study was to evaluate the impact of induced shift in polarization of cell immune response on the migration of T. regenti larvae in mammals. For this purpose, non-specifically immunomodulated mice were infected. The localization and abundance of schistosomula and associated histopathological changes were followed using routine histological techniques. Markers characterizing Th1 and Th2 systemic immune responses were followed using flow cytometry. The study revealed that the shift towards Th1 response at the time of infection correlates with the speed and intensity of schistosomula migration towards the brain and with the severity of accompanying pathologies. This indicates increased health risks associated with T. regenti infection for mammals (potentially including human) with previously modulated cell immune response that may occur under natural conditions, e.g. due to the exposure to another infectious agent.
[Mh] Termos MeSH primário: Schistosomatidae/imunologia
Células Th1/imunologia
Células Th2/imunologia
Infecções por Trematódeos/imunologia
Infecções por Trematódeos/parasitologia
[Mh] Termos MeSH secundário: Animais
Encéfalo/parasitologia
Encéfalo/patologia
Feminino
Citometria de Fluxo
Camundongos
Camundongos Endogâmicos BALB C
Camundongos Endogâmicos C57BL
Receptores de Quimiocinas/metabolismo
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Receptors, Chemokine)
[Em] Mês de entrada:1701
[Cu] Atualização por classe:170104
[Lr] Data última revisão:
170104
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160417
[St] Status:MEDLINE



página 1 de 25 ir para página                         
   


Refinar a pesquisa
  Base de dados : MEDLINE Formulário avançado   

    Pesquisar no campo  
1  
2
3
 
           



Search engine: iAH v2.6 powered by WWWISIS

BIREME/OPAS/OMS - Centro Latino-Americano e do Caribe de Informação em Ciências da Saúde