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Pesquisa : B01.050.500.644.116.150.700 [Categoria DeCS]
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[PMID]:28892742
[Au] Autor:Karthik R; Manigandan V; Saravanan R
[Ad] Endereço:Department of Medical Biotechnology, Chettinad Academy of Research and Education, Kelambakkam, Chennai-603 103, Tamil Nadu, India.
[Ti] Título:Toxicity, teratogenicity and antibacterial activity of posterior salivary gland (PSG) toxin from the cuttlefish Sepia pharaonis (Ehrenberg, 1831).
[So] Source:J Chromatogr B Analyt Technol Biomed Life Sci;1064:28-35, 2017 Oct 01.
[Is] ISSN:1873-376X
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:Toxins from the posterior salivary gland (PSG) of cuttlefishes are known toxins with pronounced toxicity. In the present study, ionic peptide rich PSG toxin from the cuttlefish S. pharaonis was isolated by ion exchange chromatography and purified by Reversed Phase High Performance Liquid Chromatography (RP-HPLC), with active fraction at a retention time of 26min. The net protein content of the PSG toxin was estimated to be 46.6mg at a proximate molecular weight of∼50kDa. Fourier Transform Infrared Spectroscopy (FT-IR) of PSG toxin revealed the presence of alcoholic OH, primary NH, alkyl CH and conjugated CONH functional groups. Circular Dichroism (CD) spectroscopy and K2D analysis of the PSG toxin confirmed the presence of secondary structure with 36.77% α-helix,12.31% ß sheet and 50.92% random coil. Scanning Electron Microscopy (SEM) of the PSG toxin eluted amberlite IRA 900 Cl resin showed surface abrasion and corrosive blebbing. Energy Dispersive X-ray Spectrometry (EDX) analysis of PSG toxin treated resin revealed increase in nitrogen and sulphur content corresponding to amino acid composition. Teratogenicity of PSG toxin against Zebrafish embryo demonstrated developmental malformations and premature hatching at a maximum tolerated dose of 1.25µM. The PSG toxin (50µM) exhibited commendable inhibitory activity with pronounced zone of inhibition against gram E. coli (10mm) and K. pneumonia (10mm). The results strongly demonstrate the toxicity of the ionic peptide rich PSG toxin from S. pharaonis and its exploitation for its promise as a potential antibacterial agent of the future.
[Mh] Termos MeSH primário: Antibacterianos/farmacologia
Toxinas Marinhas/farmacologia
Toxinas Marinhas/toxicidade
Sepia/química
Teratogênios/toxicidade
[Mh] Termos MeSH secundário: Animais
Antibacterianos/química
Bactérias/efeitos dos fármacos
Embrião não Mamífero/efeitos dos fármacos
Embrião não Mamífero/patologia
Toxinas Marinhas/química
Toxinas Marinhas/isolamento & purificação
Teratogênios/química
Peixe-Zebra
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Anti-Bacterial Agents); 0 (Marine Toxins); 0 (Teratogens)
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171010
[Lr] Data última revisão:
171010
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170912
[St] Status:MEDLINE


  2 / 209 MEDLINE  
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[PMID]:28477960
[Au] Autor:Karthik R; Manigandan V; Ebenezar KK; Vijayashree R; Saravanan R
[Ad] Endereço:Department of Medical Biotechnology, Chettinad Academy of Research and Education, Kelambakkam, 603 103, Tamil Nadu, India.
[Ti] Título:In vitro and in vivo anticancer activity of posterior salivary gland toxin from the cuttlefish Sepia pharaonis, Ehrenberg (1831).
[So] Source:Chem Biol Interact;272:10-20, 2017 Jun 25.
[Is] ISSN:1872-7786
[Cp] País de publicação:Ireland
[La] Idioma:eng
[Ab] Resumo:Posterior salivary gland (PSG) toxins are high molecular weight toxins secreted by cephalopods and gastropods which possess immense potentials in biomedical applications. In the present study, the biomedical potentials of the PSG toxin from the cuttlefish, S. pharaonis was determined in vitro and in vivo. The cytostatic potentials of the PSG toxin was determined by the lymphocyte migration inhibition assay. The PSG toxin (50 µg/ml) effectively inhibited the migration of lymphocytes across the agarose gel matrix under the presence of lipopolysaccharide mitogen. The cytotoxicity of the PSG toxin against cancer cell lines was determined using the MTT assay. The PSG toxin exhibited highest cytotoxicity against the MCF-7 breast cancer cells (IC -10.64 µM) followed by KB, HeLa and A549 cells. The PSG toxin also exhibited proportional release of LDH leakage by mitochondrial damage with an IC -13.85 µM against MCF-7 breast cancer cells. Flow cytometry analysis revealed that the PSG toxin induced apoptosis in MCF-7 cells by cell cycle arrest at G /G phase. The PSG toxin (80 mg/kg b.w.) exhibited pronounced reduction (29%) in tumor growth in experimentally induced breast carcinoma in female Balb/C mice, in vivo. Hematological analysis illustrated the restoration of blood and biochemical parameters by the PSG toxin in mice induced with tumor. Histopathology studies also revealed the restitution of morphological features in the mammary tumor and vital organs in mice treated with the PSG toxin without any observed toxicity and adverse effects. The PSG toxin further exhibited commendable potentials in the prevention of tumor metastasis into immediate organs viz lungs, thus functioning as an anti-metastatic agent. The results of the present study showed that the PSG toxin exhibited immense promise as a potential peptide based anticancer agent, in future.
[Mh] Termos MeSH primário: Antineoplásicos/toxicidade
Apoptose/efeitos dos fármacos
Glândulas Salivares/metabolismo
Sepia/metabolismo
Toxinas Biológicas/toxicidade
[Mh] Termos MeSH secundário: Células A549
Animais
Antineoplásicos/química
Antineoplásicos/uso terapêutico
Peso Corporal/efeitos dos fármacos
Neoplasias da Mama/tratamento farmacológico
Neoplasias da Mama/patologia
Movimento Celular/efeitos dos fármacos
Células Cultivadas
Senescência Celular/efeitos dos fármacos
Feminino
Pontos de Checagem da Fase G1 do Ciclo Celular/efeitos dos fármacos
Células HeLa
Coração/efeitos dos fármacos
Seres Humanos
Leucócitos Mononucleares/citologia
Leucócitos Mononucleares/efeitos dos fármacos
Leucócitos Mononucleares/metabolismo
Fígado/efeitos dos fármacos
Fígado/metabolismo
Fígado/patologia
Células MCF-7
Camundongos
Camundongos Endogâmicos BALB C
Miocárdio/metabolismo
Miocárdio/patologia
Paclitaxel/uso terapêutico
Paclitaxel/toxicidade
Toxinas Biológicas/química
Toxinas Biológicas/uso terapêutico
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Antineoplastic Agents); 0 (Toxins, Biological); P88XT4IS4D (Paclitaxel)
[Em] Mês de entrada:1706
[Cu] Atualização por classe:171116
[Lr] Data última revisão:
171116
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170508
[St] Status:MEDLINE


  3 / 209 MEDLINE  
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[PMID]:28274867
[Au] Autor:Seedevi P; Moovendhan M; Vairamani S; Shanmugam A
[Ad] Endereço:Centre of Advanced Study in Marine Biology, Faculty of Marine Sciences, Annamalai University, Parangipettai 608 502, Tamil Nadu, India. Electronic address: seedevisalem@gmail.com.
[Ti] Título:Evaluation of antioxidant activities and chemical analysis of sulfated chitosan from Sepia prashadi.
[So] Source:Int J Biol Macromol;99:519-529, 2017 Jun.
[Is] ISSN:1879-0003
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:The chitin and chitosan of S. prashadi was prepared through demineralization, deproteinzation, deacetylation process and sulfation were carried by chlorosulfonic acid in N,N-dimethylformamide. The sulfate content in chitosan was found to be 18.9%. The carbon, hydrogen and nitrogen composition of the sulfated chitosan were recorded 39.09%, 6.95% and 6.58% respectively. The structural analysis was done by using FT-IR and NMR spectroscopy technique. The DSC curves of sulfated chitosan showed a large endothermic peak resolved with T value of 54.57°C and T value of 97.46°C. The morphology of sulfated chitin and sulfated chitosan were studied by SEM. The Further in vitro antioxidant activity of sulfated chitosan was screened by scavenging activity of superoxide radical assay, hydroxyl radical scavenging assay, metal-ion chelating effect and reducing power. Its anticoagulant activity was tested for human plasma with respect to Activated Partial Thromboplastin Time (APTT) and Prothrombin Time (PT). Results prove that sulfated chitosan has potent antioxidant and anticoagulant activity.
[Mh] Termos MeSH primário: Quitosana/química
Quitosana/farmacologia
Sepia/química
Sulfatos/química
[Mh] Termos MeSH secundário: Animais
Anticoagulantes/química
Anticoagulantes/farmacologia
Antioxidantes/química
Antioxidantes/farmacologia
Quitina/análise
Seres Humanos
Radical Hidroxila/química
Ferro/química
Peso Molecular
Tempo de Tromboplastina Parcial
Tempo de Protrombina
Superóxidos/química
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Anticoagulants); 0 (Antioxidants); 0 (Sulfates); 11062-77-4 (Superoxides); 1398-61-4 (Chitin); 3352-57-6 (Hydroxyl Radical); 9012-76-4 (Chitosan); E1UOL152H7 (Iron)
[Em] Mês de entrada:1704
[Cu] Atualização por classe:170424
[Lr] Data última revisão:
170424
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170310
[St] Status:MEDLINE


  4 / 209 MEDLINE  
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[PMID]:28247274
[Au] Autor:Duysak Ö; Ugurlu E
[Ad] Endereço:Faculty of Marine Sciences and Technology, Iskenderun Technical University, 31200, Iskenderun, Hatay, Turkey. onder.duysak@iste.edu.tr.
[Ti] Título:Metal accumulations in different tissues of cuttlefish (Sepia officinalis L., 1758) in the Eastern Mediterranean coasts of Turkey.
[So] Source:Environ Sci Pollut Res Int;24(10):9614-9623, 2017 Apr.
[Is] ISSN:1614-7499
[Cp] País de publicação:Germany
[La] Idioma:eng
[Ab] Resumo:In this study, metal concentration levels (Cd, Co, Cr, Ni, and Pb) were investigated in the gill, hepatopancreas, ovary, testis, and mantle of the male and female cuttlefish Sepia officinalis in various stations (Iskenderun, Antalya, Kas, Gazipasa, and Anamur) in Mediterranean coasts of Turkey. Hepatopancreas tissue was a better indicator in terms of heavy metal concentration compared to the other tissues. In general, Cd, Co, Cr, Ni, and Pb accumulation for the male was found more than that of the female, whereas Cd and Ni accumulation was found higher in the female. There was a relationship among the metals in the form of Co > Pb > Ni > Cd > Cr in the mantle tissue. The Pb concentration over the recommended limits was found in cuttlefish of Anamur, Antalya, and Iskenderun stations.
[Mh] Termos MeSH primário: Decapodiformes
Sepia
[Mh] Termos MeSH secundário: Animais
Monitoramento Ambiental
Feminino
Hepatopâncreas/química
Masculino
Metais Pesados
Turquia
Poluentes Químicos da Água
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Metals, Heavy); 0 (Water Pollutants, Chemical)
[Em] Mês de entrada:1706
[Cu] Atualização por classe:171103
[Lr] Data última revisão:
171103
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170302
[St] Status:MEDLINE
[do] DOI:10.1007/s11356-017-8685-2


  5 / 209 MEDLINE  
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[PMID]:27714785
[Au] Autor:O'Brien CE; Mezrai N; Darmaillacq AS; Dickel L
[Ad] Endereço:Groupe Mémoire et Plasticité Comportementale (GMPc EA 4259), Université de Caen-Normandie, Caen, France.
[Ti] Título:Behavioral development in embryonic and early juvenile cuttlefish (Sepia officinalis).
[So] Source:Dev Psychobiol;59(2):145-160, 2017 03.
[Is] ISSN:1098-2302
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Though a mollusc, the cuttlefish Sepia officinalis possesses a sophisticated brain, advanced sensory systems, and a large behavioral repertoire. Cuttlefish provide a unique perspective on animal behavior due to their phylogenic distance from more traditional (vertebrate) models. S. officinalis is well-suited to addressing questions of behavioral ontogeny. As embryos, they can perceive and learn from their environment and experience no direct parental care. A marked progression in learning and behavior is observed during late embryonic and early juvenile development. This improvement is concomitant with expansion and maturation of the vertical lobe, the cephalopod analog of the mammalian hippocampus. This review synthesizes existing knowledge regarding embryonic and juvenile development in this species in an effort to better understand cuttlefish behavior and animal behavior in general. It will serve as a guide to future researchers and encourage greater awareness of the utility of this species to behavioral science.
[Mh] Termos MeSH primário: Comportamento Animal/fisiologia
Embrião não Mamífero/fisiologia
Aprendizagem/fisiologia
Sepia/fisiologia
[Mh] Termos MeSH secundário: Animais
Sepia/crescimento & desenvolvimento
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Em] Mês de entrada:1709
[Cu] Atualização por classe:171122
[Lr] Data última revisão:
171122
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161008
[St] Status:MEDLINE
[do] DOI:10.1002/dev.21476


  6 / 209 MEDLINE  
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[PMID]:28076505
[Au] Autor:Zhang W; Liu K; Li L; Li Y; Sui X; Rao Y; Wu J; Wu Q
[Ad] Endereço:Fellow Master degree, Postgraduate Program in Biomedcial Materimals, Lingnan Normal University, Round Beibu Gulf Institute for the Protection and Utilization of Marine Animals in Medicine (RBGPUM), China. Conception, design, intellectual and scientific content of the study; acquisition and interpret
[Ti] Título:Therapeutic effect of low molecular weight chitosan containing sepia ink on ethanol-induced gastric ulcer in rats.
[So] Source:Acta Cir Bras;31(12):813-820, 2016 Dec.
[Is] ISSN:1678-2674
[Cp] País de publicação:Brazil
[La] Idioma:eng
[Ab] Resumo:PURPOSE: : To evaluate the role of low molecular chitosan containing sepia ink (LMCS) in ethanol-induced (5 ml/kg) gastric ulcer in rats. METHODS: : Animals were divided into four groups (n = 12): normal group (Normal), negative control group (Con), experiment group (LMCS) and positive control Omeprazole group (OMZ). Gastric empty rate was detected in the first 7 days. Rats were sacrificed at 7, 14 and 21 day for histology and ELISA detections. RESULTS: : Gastric empty was no significant differences among the groups (P > 0.05). Histological observation showed gastric mucosal LMCS treated had better healing effect. Hydroxyproline (Hyp) was significantly increased from 7 day (P < 0.05). LMCS significantly inhibited malondialdehyde (MDA) generation for lipid peroxidation from 7 day (P < 0.05). LMCS significantly promoted the activity of superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase (GPx) at the earlier stage (P < 0.05). OMZ had the similar effects above. As for myeloperoxidase (MPO), LMCS significantly decreased and restored it to normal levels from 7 day (P < 0.05), it is earlier than OMZ which is from 14 day. CONCLUSION: : LMCS can improve gastric mucosa tissue repair, exert significant influences on oxidative and antioxidant enzyme activities and neutrophil infiltration.
[Mh] Termos MeSH primário: Antiulcerosos/uso terapêutico
Antioxidantes/farmacologia
Quitosana/uso terapêutico
Mucosa Gástrica/efeitos dos fármacos
Sepia/química
Úlcera Gástrica/tratamento farmacológico
[Mh] Termos MeSH secundário: Animais
Antioxidantes/metabolismo
Quitosana/química
Modelos Animais de Doenças
Etanol
Mucosa Gástrica/patologia
Hidroxiprolina/metabolismo
Tinta
Malondialdeído/metabolismo
Peso Molecular
Distribuição Aleatória
Ratos
Úlcera Gástrica/induzido quimicamente
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Anti-Ulcer Agents); 0 (Antioxidants); 3K9958V90M (Ethanol); 4Y8F71G49Q (Malondialdehyde); 9012-76-4 (Chitosan); RMB44WO89X (Hydroxyproline)
[Em] Mês de entrada:1706
[Cu] Atualização por classe:170627
[Lr] Data última revisão:
170627
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170112
[St] Status:MEDLINE


  7 / 209 MEDLINE  
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[PMID]:27901505
[Au] Autor:Tao Z; Liu L; Chen X; Zhou S; Wang G
[Ad] Endereço:School of Marine Science, Ningbo University, Ningbo 315211, PR China.
[Ti] Título:First isolation of Miamiensis avidus (Ciliophora: Scuticociliatida) associated with skin ulcers from reared pharaoh cuttlefish Sepia pharaonis.
[So] Source:Dis Aquat Organ;122(1):67-71, 2016 11 22.
[Is] ISSN:0177-5103
[Cp] País de publicação:Germany
[La] Idioma:eng
[Ab] Resumo:In the winter of 2015, a skin ulcer disease outbreak occurred in a pharaoh cuttlefish Sepia pharaonis population cultured on a land-based fish farm in China. Affected cuttlefish (about 60% of the population) were characterized as having developed ulcers on the dorsal skin, fin fringe, or distal mantle tip. Masses of a ciliated protozoan were isolated from skin ulcers. The ciliate was identified as Miamiensis avidus based on the morphological features of living and protargol-impregnated specimens. This identification was also supported by high sequence similarity of the small subunit ribosomal RNA gene (100%) and another ribosomal DNA region (including the 2 internal transcribed spacers and the 5.8S gene; 99%) with published sequences of fish parasitic M. avidus strains. M. avidus is known to be a histophagous marine fish parasite. This report describes the first case of M. avidus associated with skin ulcers in a cephalopod mollusk (Mollusca, Cephalopoda). This finding suggests that M. avidus may infect a phylogenetically broader range of hosts than what has previously been reported. Furthermore, M. avidus may pose a health risk to hatchery-reared cephalopods.
[Mh] Termos MeSH primário: Cilióforos/fisiologia
Sepia/parasitologia
[Mh] Termos MeSH secundário: Animais
Aquicultura
Cilióforos/isolamento & purificação
Interações Hospedeiro-Parasita
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Em] Mês de entrada:1706
[Cu] Atualização por classe:170622
[Lr] Data última revisão:
170622
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161201
[St] Status:MEDLINE


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[PMID]:27782082
[Au] Autor:Liu C; Zhao F; Yan J; Liu C; Liu S; Chen S
[Ad] Endereço:Key Laboratory of Sustainable Development of Marine Fisheries, Ministry of Agriculture, Yellow Sea Fisheries Research Institute, Chinese Academy of Fishery Sciences, Qingdao 266071, China. liuchl@ysfri.ac.cn.
[Ti] Título:Transcriptome Sequencing and De Novo Assembly of Golden Cuttlefish Sepia esculenta Hoyle.
[So] Source:Int J Mol Sci;17(10), 2016 Oct 22.
[Is] ISSN:1422-0067
[Cp] País de publicação:Switzerland
[La] Idioma:eng
[Ab] Resumo:Golden cuttlefish Hoyle is an economically important cephalopod species. However, artificial hatching is currently challenged by low survival rate of larvae due to abnormal embryonic development. Dissecting the genetic foundation and regulatory mechanisms in embryonic development requires genomic background knowledge. Therefore, we carried out a transcriptome sequencing on Sepia embryos and larvae via mRNA-Seq. 32,597,241 raw reads were filtered and assembled into 98,615 unigenes (N50 length at 911 bp) which were annotated in NR database, GO and KEGG databases respectively. Digital gene expression analysis was carried out on cleavage stage embryos, healthy larvae and malformed larvae. Unigenes functioning in cell proliferation exhibited higher transcriptional levels at cleavage stage while those related to animal disease and organ development showed increased transcription in malformed larvae. Homologs of key genes in regulatory pathways related to early development of animals were identified in Sepia. Most of them exhibit higher transcriptional levels in cleavage stage than larvae, suggesting their potential roles in embryonic development of Sepia. The de novo assembly of Sepia transcriptome is fundamental genetic background for further exploration in Sepia research. Our demonstration on the transcriptional variations of genes in three developmental stages will provide new perspectives in understanding the molecular mechanisms in early embryonic development of cuttlefish.
[Mh] Termos MeSH primário: Regulação da Expressão Gênica no Desenvolvimento
Genoma
Anotação de Sequência Molecular
Sepia/genética
Transcriptoma
[Mh] Termos MeSH secundário: Animais
Embrião não Mamífero/metabolismo
Ontologia Genética
Redes Reguladoras de Genes
Larva/genética
Larva/crescimento & desenvolvimento
Redes e Vias Metabólicas/genética
Sepia/crescimento & desenvolvimento
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1703
[Cu] Atualização por classe:170323
[Lr] Data última revisão:
170323
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161027
[St] Status:MEDLINE


  9 / 209 MEDLINE  
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[PMID]:27743598
[Au] Autor:Abd El-Latif AA; Sayed AA; Soliman AM; Fahmy SR
[Ad] Endereço:Zoology Department, Faculty of Science, Cairo University, 12613, Giza, Egypt. Electronic address: chem.asmaa19@yahoo.com.
[Ti] Título:Exploration of the therapeutic potential effect of Sepia officinalis in animal model of sepsis induced by cecal ligation and puncture.
[So] Source:Injury;47(12):2709-2717, 2016 Dec.
[Is] ISSN:1879-0267
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:OBJECTIVE: The present investigation explored the therapeutic potential effect of Sepia officinalis body tissue (SOBT) and Sepia officinalis polysaccharide (SOP) extracts, in animal model of sepsis [induced by cecal ligation and puncture (CLP)]. MATERIALS AND METHODS: Experimental animals were divided into 4 groups, Group 1: Sham control rats. Group 2: Septic rats. Group 3: Septic rats treated with methanolic extract of Sepia officinalis body tissue (SOBT) (500mg/kg body weight) for 2days. Group 4: Septic rats treated with Sepia officinalis polysaccharide (SOP) extract (200mg/kg body weight) for 2days. RESULTS: The antioxidant activity of SOBT and SOP was proven by DPPH test. CLP-induced liver and kidney toxicities showed by an increase in the ALAT, ASAT, γGT, ALP, creatinine, BUN and uric acid concentrations in serum. Moreover, CLP-induced oxidative stress in liver and kidney evidenced by the increase of MDA levels, decrease in GSH concentrations and decrease in the enzymatic antioxidants (SOD, CAT, GST). In addition, CLP caused decrease in CYP1A2 content in liver. CONCLUSIONS: Our findings demonstrate the therapeutic efficacy of SOBT and SOP in liver and kidney disorders. Therefore this study suggests that SOBT and SOP could be a potential therapeutic agents for sepsis treatment.
[Mh] Termos MeSH primário: Antioxidantes/farmacologia
Ceco/patologia
Modelos Animais de Doenças
Rim/patologia
Fígado/patologia
Sepia/química
Sepse/patologia
[Mh] Termos MeSH secundário: Animais
Ativação Enzimática
Peroxidação de Lipídeos
Testes de Função Hepática
Masculino
Estresse Oxidativo
Ratos
Ratos Wistar
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Antioxidants)
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170904
[Lr] Data última revisão:
170904
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161017
[St] Status:MEDLINE


  10 / 209 MEDLINE  
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[PMID]:27530149
[Au] Autor:Souidenne D; Florent I; Dellinger M; Justine JL; Romdhane MS; Furuya H; Grellier P
[Ad] Endereço:UMR 7245 CNRS MCAM, Muséum National d'Histoire Naturelle, Sorbonne Universités, CP 52, 57 rue Cuvier, 75005 Paris, France - UR03AGRO1 Ecosystèmes et Ressources Aquatiques, Institut National Agronomique de Tunisie, 43 avenue Charles Nicolle, 1082 Tunis, Tunisia.
[Ti] Título:Diversity of apostome ciliates, Chromidina spp. (Oligohymenophorea, Opalinopsidae), parasites of cephalopods of the Mediterranean Sea.
[Ti] Título:Diversité des ciliés apostomes, Chromidina spp. (Oligohymenophorea, Opalinopsidae) parasites de céphalopodes en mer Méditerranée..
[So] Source:Parasite;23:33, 2016.
[Is] ISSN:1776-1042
[Cp] País de publicação:France
[La] Idioma:eng
[Ab] Resumo:Chromidina spp. are enigmatic apostome ciliates (Oligohymenophorea, Opalinopsidae) that parasitise the renal and pancreatic appendages of cephalopods. Only four species have been described, among which only three have been formally named. No DNA sequence has been reported so far. To investigate Chromidina spp. diversity, we sampled cephalopods in the Mediterranean Sea off Tunis, Tunisia, and identified two distinct Chromidina spp. in two different host species: Loligo vulgaris and Sepia officinalis. From haematoxylin-stained slides, we described morphological traits for these parasitic species and compared them to previous descriptions. We also re-described the morphology of Chromidina elegans (Foettinger, 1881) from Chatton and Lwoff's original materials and designated a neohapantotype and paraneohapantotypes for this species. We describe a new species, Chromidina chattoni Souidenne, Florent and Grellier n. sp., found in L. vulgaris off Tunisia, and evidence for a probable novel species, found in S. officinalis off Tunisia, although this latter species presents similarities to some morphological stages previously described for Chromidina cortezi Hochberg, 1971. We amplified, for the first time, an 18S rDNA marker for these two Chromidina species. Phylogenetic analysis supports the association of Chromidina within apostome ciliates. Genetic distance analysis between 18S rDNA sequences of representative apostomes indicates Pseudocollinia as the most closely related genus to Chromidina.
[Mh] Termos MeSH primário: Cefalópodes/parasitologia
Oligoimenóforos/classificação
Filogenia
[Mh] Termos MeSH secundário: Animais
Teorema de Bayes
DNA Ribossômico/química
França
Funções Verossimilhança
Loligo/parasitologia
Mar Mediterrâneo
Oligoimenóforos/genética
Oligoimenóforos/ultraestrutura
RNA Ribossômico 18S/genética
Sepia/parasitologia
Alinhamento de Sequência
Tunísia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (DNA, Ribosomal); 0 (RNA, Ribosomal, 18S)
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170810
[Lr] Data última revisão:
170810
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160818
[St] Status:MEDLINE
[do] DOI:10.1051/parasite/2016033



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