Base de dados : MEDLINE
Pesquisa : B01.300.107.800.629 [Categoria DeCS]
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[PMID]:28809955
[Au] Autor:Wang Y; Li H; Feng G; Du L; Zeng D
[Ad] Endereço:Institute of Pesticide and Environmental Toxicology, Guangxi University, Nanning, PR China.
[Ti] Título:Biodegradation of diuron by an endophytic fungus Neurospora intermedia DP8-1 isolated from sugarcane and its potential for remediating diuron-contaminated soils.
[So] Source:PLoS One;12(8):e0182556, 2017.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:A diuron-degrading endophyte DP8-1 was isolated from sugarcane root grown in diuron-treated soil in the present study. The endophyte was identified as Neurospora intermedia based on the morphological characteristics and sequence analysis. The fermentation parameters including temperature, pH, inoculation size, carbon source, and initial diuron concentration were also investigated for the optimization of degradation efficiency. The results indicated that strain DP8-1 was capable of degrading up to 99% diuron within 3 days under the optimal degrading condition. The study of degradation spectrum indicated that strain DP8-1 could also degrade and utilize fenuron, monuron, metobromuron, isoproturon, chlorbromuron, linuron, and chlortoluron as substrate for strain growth. On basis of liquid chromatography-mass spectrometry analysis for the products of the degradation of diuron, strain DP8-1 metabolized diuron to produce N-(3,4-dichlorophenyl)-urea and N-(3,4-dichlorophenyl)-N-methylurea through sequential N-dealkylations. In a soil bioaugmentation experiment, the inoculation of strain DP8-1 into diuron-treated soil effectively enhanced the disappearance rate of diuron.
[Mh] Termos MeSH primário: Biodegradação Ambiental
Diurona/metabolismo
Neurospora/metabolismo
Saccharum/microbiologia
Poluentes do Solo/metabolismo
[Mh] Termos MeSH secundário: Cromatografia Líquida
Espectrometria de Massas
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Soil Pollutants); 9I3SDS92WY (Diuron)
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171011
[Lr] Data última revisão:
171011
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170816
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0182556


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[PMID]:28669407
[Au] Autor:Bergonzo C; Cheatham TE
[Ad] Endereço:University of Utah, Salt Lake City, Utah.
[Ti] Título:Mg Binding Promotes SLV as a Scaffold in Varkud Satellite Ribozyme SLI-SLV Kissing Loop Junction.
[So] Source:Biophys J;113(2):313-320, 2017 Jul 25.
[Is] ISSN:1542-0086
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Though the structure of the substrate stem loop I (SLI)-stem loop V (SLV) kissing loop junction of the Varkud Satellite ribozyme has been experimentally characterized, the dynamics of this Mg -dependent loop-loop interaction have been elusive. Specifically, each hairpin loop contains a U-turn motif, but only SLV shows a conformational shift triggered by Mg ion association. Here, we use molecular dynamics simulations to analyze the binding and dynamics of this kissing loop junction. We show that SLV acts as a scaffold, providing stability to the junction. Mg ions associate with SLV when it is part of the junction in a manner similar to when it is unbound, but there is no specificity in Mg binding for the SLI loop. This suggests that the entropic penalty of ordering the larger SLI is too high, allowing SLV to act as a scaffold for multiple substrate loop sequences.
[Mh] Termos MeSH primário: Endorribonucleases/metabolismo
Magnésio/metabolismo
Conformação de Ácido Nucleico
RNA Catalítico/metabolismo
RNA Fúngico/metabolismo
[Mh] Termos MeSH secundário: Cátions Bivalentes/química
Cátions Bivalentes/metabolismo
Endorribonucleases/química
Ligações de Hidrogênio
Magnésio/química
Modelos Genéticos
Simulação de Dinâmica Molecular
Neurospora
RNA Catalítico/química
RNA Fúngico/química
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Cations, Divalent); 0 (RNA, Catalytic); 0 (RNA, Fungal); EC 3.1.- (Endoribonucleases); EC 3.1.27.- (varkud satellite ribozyme); I38ZP9992A (Magnesium)
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170821
[Lr] Data última revisão:
170821
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170704
[St] Status:MEDLINE


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[PMID]:28648778
[Au] Autor:Liu X; Dang Y; Matsu-Ura T; He Y; He Q; Hong CI; Liu Y
[Ad] Endereço:Department of Physiology, University of Texas Southwestern Medical Center, Dallas, TX 75390-9040, USA.
[Ti] Título:DNA Replication Is Required for Circadian Clock Function by Regulating Rhythmic Nucleosome Composition.
[So] Source:Mol Cell;67(2):203-213.e4, 2017 Jul 20.
[Is] ISSN:1097-4164
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Although the coupling between circadian and cell cycles allows circadian clocks to gate cell division and DNA replication in many organisms, circadian clocks were thought to function independently of cell cycle. Here, we show that DNA replication is required for circadian clock function in Neurospora. Genetic and pharmacological inhibition of DNA replication abolished both overt and molecular rhythmicities by repressing frequency (frq) gene transcription. DNA replication is essential for the rhythmic changes of nucleosome composition at the frq promoter. The FACT complex, known to be involved in histone disassembly/reassembly, is required for clock function and is recruited to the frq promoter in a replication-dependent manner to promote replacement of histone H2A.Z by H2A. Finally, deletion of H2A.Z uncoupled the dependence of the circadian clock on DNA replication. Together, these results establish circadian clock and cell cycle as interdependent coupled oscillators and identify DNA replication as a critical process in the circadian mechanism.
[Mh] Termos MeSH primário: Relógios Circadianos
Ritmo Circadiano
Replicação do DNA
DNA Fúngico/metabolismo
Neurospora/metabolismo
Nucleossomos/metabolismo
[Mh] Termos MeSH secundário: Animais
DNA Fúngico/química
DNA Fúngico/genética
Proteínas Fúngicas/genética
Proteínas Fúngicas/metabolismo
Regulação Fúngica da Expressão Gênica
Proteínas de Grupo de Alta Mobilidade/genética
Proteínas de Grupo de Alta Mobilidade/metabolismo
Histonas/genética
Histonas/metabolismo
Neurospora/genética
Conformação de Ácido Nucleico
Nucleossomos/química
Nucleossomos/genética
Antígeno Nuclear de Célula em Proliferação/genética
Antígeno Nuclear de Célula em Proliferação/metabolismo
Regiões Promotoras Genéticas
Conformação Proteica
Relação Estrutura-Atividade
Fatores de Tempo
Transcrição Genética
Fatores de Elongação da Transcrição/genética
Fatores de Elongação da Transcrição/metabolismo
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (DNA, Fungal); 0 (FRQ protein, Neurospora crassa); 0 (Fungal Proteins); 0 (High Mobility Group Proteins); 0 (Histones); 0 (Nucleosomes); 0 (Proliferating Cell Nuclear Antigen); 0 (Transcriptional Elongation Factors)
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170926
[Lr] Data última revisão:
170926
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170627
[St] Status:MEDLINE


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[PMID]:28527179
[Au] Autor:Dunlap JC; Loros JJ
[Ad] Endereço:Department of Molecular and Systems Biology, Geisel School of Medicine at Dartmouth, Hanover, NH 03755.
[Ti] Título:Making Time: Conservation of Biological Clocks from Fungi to Animals.
[So] Source:Microbiol Spectr;5(3), 2017 May.
[Is] ISSN:2165-0497
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:The capacity for biological timekeeping arose at least three times through evolution, in prokaryotic cyanobacteria, in cells that evolved into higher plants, and within the group of organisms that eventually became the fungi and the animals. is a tractable model system for understanding the molecular bases of circadian rhythms in the last of these groups, and is perhaps the most intensively studied circadian cell type. Rhythmic processes described in fungi include growth rate, stress responses, developmental capacity, and sporulation, as well as much of metabolism; fungi use clocks to anticipate daily environmental changes. A negative feedback loop comprises the core of the circadian system in fungi and animals. In , the best studied fungal model, it is driven by two transcription factors, WC-1 and WC-2, that form the White Collar Complex (WCC). WCC elicits expression of the gene. FRQ complexes with other proteins, physically interacts with the WCC, and reduces its activity; the kinetics of these processes is strongly influenced by progressive phosphorylation of FRQ. When FRQ becomes sufficiently phosphorylated that it loses the ability to influence WCC activity, the circadian cycle starts again. Environmental cycles of light and temperature influence and FRQ expression and thereby reset the internal circadian clocks. The molecular basis of circadian output is also becoming understood. Taken together, molecular explanations are emerging for all the canonical circadian properties, providing a molecular and regulatory framework that may be extended to many members of the fungal and animal kingdoms, including humans.
[Mh] Termos MeSH primário: Relógios Biológicos/fisiologia
Fungos/fisiologia
[Mh] Termos MeSH secundário: Animais
Relógios Biológicos/genética
Relógios Biológicos/efeitos da radiação
Ritmo Circadiano
Proteínas de Ligação a DNA/genética
Proteínas de Ligação a DNA/fisiologia
Retroalimentação Fisiológica
Proteínas Fúngicas/genética
Proteínas Fúngicas/fisiologia
Fungos/genética
Fungos/metabolismo
Regulação Fúngica da Expressão Gênica
Genes Fúngicos
Seres Humanos
Luz
Modelos Biológicos
Neurospora/fisiologia
Fotobiologia
Temperatura Ambiente
Fatores de Transcrição/metabolismo
Fatores de Transcrição/fisiologia
Transcrição Genética
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Nm] Nome de substância:
0 (DNA-Binding Proteins); 0 (FRQ protein, Neurospora crassa); 0 (Fungal Proteins); 0 (Transcription Factors); 0 (wc-1 protein, Neurospora crassa); 0 (white collar 2 protein, Neurospora)
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170926
[Lr] Data última revisão:
170926
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170521
[St] Status:MEDLINE
[do] DOI:10.1128/microbiolspec.FUNK-0039-2016


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[PMID]:28476998
[Au] Autor:Hamedi S; Shojaosadati SA; Shokrollahzadeh S; Hashemi-Najafabadi S
[Ad] Endereço:Department of Cellulose and Paper Technology, Faculty of New Technologies and Energy Engineering, Shahid Beheshti University, P.O. Box: 47815-168, Zirab Campus, Tehran, Iran.
[Ti] Título:Mechanism study of silver nanoparticle production using .
[So] Source:IET Nanobiotechnol;11(2):157-163, 2017 Mar.
[Is] ISSN:1751-8741
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Elucidation of the molecular mechanism of silver nanoparticle (AgNP) synthesis is necessary to control nanoparticle size, shape, and monodispersity. In this study, the mechanism of AgNP formation by was investigated. The higher production rate of AgNP formation using a culture supernatant heat-treated at 100° and 121°C relative to that with an un-treated culture supernatant indicated that the native form of the molecular species is not essential. The effect of the protein molecular weight (MW) on the nanoparticle size distribution and average size was studied by means of ultraviolet-visible spectroscopy and dynamic light scattering. Using un-treated and concentrated cell-free filtrate passed through 10 and 20 kDa cut-off filters led to the production of AgNPs with average sizes of 25, 30, and 34 nm, respectively. Also, using the permeate fraction of cell-free filtrate passed through a 100 kDa cut-off filter led to the formation of the smallest nanoparticles with the narrowest size distribution (average size of 16 nm and polydispersity index of 0.18). Sodium dodecyl sulphate polyacrylamide gel electrophoresis analysis of the fungal extracellular proteins showed two notable bands with the MWs of 15 and 23 kDa that are involved in the reduction and stabilisation of the nanoparticles, respectively.
[Mh] Termos MeSH primário: Produtos Biológicos/metabolismo
Nanopartículas/química
Nanopartículas/ultraestrutura
Neurospora/metabolismo
Prata/química
Prata/metabolismo
[Mh] Termos MeSH secundário: Produtos Biológicos/síntese química
Sistema Livre de Células
Teste de Materiais
Neurospora/química
Neurospora/classificação
Tamanho da Partícula
Especificidade da Espécie
Propriedades de Superfície
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Biological Products); 3M4G523W1G (Silver)
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170817
[Lr] Data última revisão:
170817
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170507
[St] Status:MEDLINE
[do] DOI:10.1049/iet-nbt.2016.0038


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[PMID]:28229961
[Au] Autor:Kasbekar DP; Rekha S
[Ad] Endereço:Centre for DNA Fingerprinting and Diagnostics, Hyderabad 500 001, India, kas@cdfd.org.in.
[Ti] Título: crosses heterozygous for hybrid translocation strains produce rare eight-spored asci-bearing heterokaryotic ascospores.
[So] Source:J Biosci;42(1):15-21, 2017 Mar.
[Is] ISSN:0973-7138
[Cp] País de publicação:India
[La] Idioma:eng
[Ab] Resumo:During ascogenesis in Neurospora, the ascospores are partitioned at the eight-nucleus stage that follows meiosis and a post-meiotic mitosis, and the ascospores that form in eight-spored asci are usually homokaryotic. We had previously created novel TNt strains by introgressing four Neurospora crassa insertional translocations (EB4, IBj5, UK14-1, and B362i) into N. tetrasperma. We now show that crosses of all the TNt strains with single-mating-type derivatives of the standard N. tetrasperma pseudohomothallic strain 85 (viz. T a x 85A or T A x 85a) can produce rare eight-spored asci that contain heterokaryotic ascospores, or ascospores with other unexpected genotypes. Our results suggest that these rare asci result from the interposition of additional mitoses between the post-meiotic mitosis and the partitioning of nuclei into ascospores, leading to the formation of supernumerary nuclei that then generate the heterokaryotic ascospores. The rare asci probably represent a background level of ascus dysgenesis wherein the partitioning of ascospores becomes uncoupled from the post-meiotic mitosis. Ordinarily, the severest effect of such dysgenesis, the production of mating-type heterokaryons, would be suppressed by the N. crassa tol (tolerant) gene, thus explaining why such dysgenesis remained undetected thus far.
[Mh] Termos MeSH primário: Núcleo Celular/genética
Meiose/genética
Neurospora/genética
Esporos Fúngicos/genética
[Mh] Termos MeSH secundário: Cruzamentos Genéticos
Genótipo
Heterozigoto
Mitose
Neurospora/crescimento & desenvolvimento
Esporos Fúngicos/crescimento & desenvolvimento
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1703
[Cu] Atualização por classe:171108
[Lr] Data última revisão:
171108
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170224
[St] Status:MEDLINE


  7 / 3415 MEDLINE  
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[PMID]:27864017
[Au] Autor:Mahboubi A; Ferreira JA; Taherzadeh MJ; Lennartsson PR
[Ad] Endereço:Swedish Centre for Resource Recovery, University of Borås, 50190 Borås, Sweden.
[Ti] Título:Value-added products from dairy waste using edible fungi.
[So] Source:Waste Manag;59:518-525, 2017 Jan.
[Is] ISSN:1879-2456
[Cp] País de publicação:United States
[La] Idioma:eng
[Mh] Termos MeSH primário: Biomassa
Laticínios
Microbiologia de Alimentos
Indústria de Processamento de Alimentos/métodos
Alimentos
Fungos/química
[Mh] Termos MeSH secundário: Animais
Aspergillus oryzae
Indústria de Laticínios
Etanol/química
Concentração de Íons de Hidrogênio
Resíduos Industriais
Ácido Láctico/química
Lactose/química
Leite
Neurospora
Proteínas/química
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Industrial Waste); 0 (Proteins); 33X04XA5AT (Lactic Acid); 3K9958V90M (Ethanol); J2B2A4N98G (Lactose)
[Em] Mês de entrada:1705
[Cu] Atualização por classe:170501
[Lr] Data última revisão:
170501
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161120
[St] Status:MEDLINE


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[PMID]:27812897
[Au] Autor:Pamidipati S; Ahmed A
[Ad] Endereço:Department of Chemical Engineering, Birla Institute of Technology and Science Pilani Hyderabad Campus, Jawahar Nagar, Shameerpet Mandal, Hyderabad, 500078, India.
[Ti] Título:Degradation of Lignin in Agricultural Residues by locally Isolated Fungus Neurospora discreta.
[So] Source:Appl Biochem Biotechnol;181(4):1561-1572, 2017 Apr.
[Is] ISSN:1559-0291
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Locally isolated fungus, Neurospora discreta, was evaluated for its ability to degrade lignin in two agricultural residues: cocopeat and sugarcane bagasse with varying lignin concentrations and structures. Using Klason's lignin estimation, high-performance liquid chromatography, and UV-visible spectroscopy, we found that N. discreta was able to degrade up to twice as much lignin in sugarcane bagasse as the well-known white rot fungus Phanerochaete chrysosporium and produced nearly 1.5 times the amount of lignin degradation products in submerged culture. Based on this data, N. discreta is a promising alternative to white rot fungi for faster microbial pre-treatment of agricultural residues. This paper presents the lignin degrading capability of N. discreta for the first time and also discusses the difference in biodegradability of cocopeat and sugarcane bagasse as seen from the analysis carried out using Fourier transform infrared spectroscopy.
[Mh] Termos MeSH primário: Agricultura
Lignina/metabolismo
Neurospora/metabolismo
[Mh] Termos MeSH secundário: Biodegradação Ambiental
Celulose/química
Celulose/metabolismo
Cocos/química
Lignina/química
Neurospora/isolamento & purificação
Saccharum/química
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (guaiacyl monolignol); 0 (syringyl monolignol); 9004-34-6 (Cellulose); 9005-53-2 (Lignin); 9006-97-7 (bagasse)
[Em] Mês de entrada:1704
[Cu] Atualização por classe:170618
[Lr] Data última revisão:
170618
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161105
[St] Status:MEDLINE
[do] DOI:10.1007/s12010-016-2302-6


  9 / 3415 MEDLINE  
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[PMID]:27395794
[Au] Autor:Syed F; Ali K; Asad MJ; Fraz MG; Khan Z; Imran M; Taj R; Ahmad A
[Ad] Endereço:Institute of Chemical Sciences, Biochemistry Section, University of Peshawar, 25120, Pakistan.
[Ti] Título:Preparation and characterization of a green nano-support for the covalent immobilization of glucoamylase from Neurospora sitophila.
[So] Source:J Photochem Photobiol B;162:309-317, 2016 Sep.
[Is] ISSN:1873-2682
[Cp] País de publicação:Switzerland
[La] Idioma:eng
[Ab] Resumo:The preparation of green nano supports for the covalent immobilization of enzymes is of special interest both from the economic and environmental point of view. In this contribution, we report on the synthesis of phytochemicals coated silver nanoparticles, which were used as a novel green support for the covalent immobilization of glucoamylase isolated from Neurospora sitophila. The aqueous extract of Fagonia indica was used as a source of reducing and capping agents for the reduction of silver ions into silver nanoparticles. The prepared nanoparticles were characterized by various analytical techniques. UV-visible spectroscopy was used to detect the characteristic surface plasmon resonance bands (426, 438nm) of the silver nanoparticles. The biosynthesized silver nanoparticles were mostly spherical in shapes with an average particle size of 30-40nm (TEM and DLS measurements). X-ray diffraction and energy dispersive X-ray studies confirmed the face centered cubic crystalline form and elemental composition of the biogenic silver nanoparticles respectively. FTIR study revealed that plant polyphenolics and protein were mainly involved in the reduction and capping of silver ions. Glucoamylase from Neurospora sitophila was covalently immobilized to these nanoparticles via EDC (1-(3-(dimethylamino) propyl) 3-ethylcarbodiimidehydrochloride) coupling reaction. The immobilized enzyme exhibited higher pH and thermal stabilities as compared to the free enzyme. The kinetic constant (KM) value for the immobilized glucoamylase was higher (0.73mg/mL) than its free counterpart (0.44mg/mL), whereas the Vmax value was slightly higher for the immobilized glucoamylase. The findings of this study conclude that the newly developed green method for the synthesis of green nano-support is simple, cost effective and could be successfully used for the immobilization of various enzymes and other macromolecules.
[Mh] Termos MeSH primário: Enzimas Imobilizadas/química
Glucana 1,4-alfa-Glucosidase/química
Nanopartículas Metálicas/química
Neurospora/enzimologia
[Mh] Termos MeSH secundário: Estabilidade Enzimática
Enzimas Imobilizadas/metabolismo
Glucana 1,4-alfa-Glucosidase/metabolismo
Química Verde
Concentração de Íons de Hidrogênio
Cinética
Tamanho da Partícula
Prata/química
Propriedades de Superfície
Temperatura Ambiente
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Enzymes, Immobilized); 3M4G523W1G (Silver); EC 3.2.1.3 (Glucan 1,4-alpha-Glucosidase)
[Em] Mês de entrada:1703
[Cu] Atualização por classe:171009
[Lr] Data última revisão:
171009
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160711
[St] Status:MEDLINE


  10 / 3415 MEDLINE  
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[PMID]:27166370
[Au] Autor:Lacroix-Labonté J; Girard N; Dagenais P; Legault P
[Ad] Endereço:Département de Biochimie et Médecine Moléculaire, Université de Montréal, C.P. 6128, Succursale Centre-Ville, Montréal, QC H3C 3J7, Canada.
[Ti] Título:Rational engineering of the Neurospora VS ribozyme to allow substrate recognition via different kissing-loop interactions.
[So] Source:Nucleic Acids Res;44(14):6924-34, 2016 Aug 19.
[Is] ISSN:1362-4962
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:The Neurospora VS ribozyme is a catalytic RNA that has the unique ability to specifically recognize and cleave a stem-loop substrate through formation of a highly stable kissing-loop interaction (KLI). In order to explore the engineering potential of the VS ribozyme to cleave alternate substrates, we substituted the wild-type KLI by other known KLIs using an innovative engineering method that combines rational and combinatorial approaches. A bioinformatic search of the protein data bank was initially performed to identify KLIs that are structurally similar to the one found in the VS ribozyme. Next, substrate/ribozyme (S/R) pairs that incorporate these alternative KLIs were kinetically and structurally characterized. Interestingly, several of the resulting S/R pairs allowed substrate cleavage with substantial catalytic efficiency, although with reduced activity compared to the reference S/R pair. Overall, this study describes an innovative approach for RNA engineering and establishes that the KLI of the trans VS ribozyme can be adapted to cleave other folded RNA substrates.
[Mh] Termos MeSH primário: Endorribonucleases/metabolismo
Neurospora/enzimologia
Conformação de Ácido Nucleico
Engenharia de Proteínas
RNA Catalítico/metabolismo
[Mh] Termos MeSH secundário: Sequência de Bases
Biocatálise
Biologia Computacional
Cristalografia por Raios X
Bases de Dados de Proteínas
Endorribonucleases/química
Estabilidade Enzimática
Cinética
Espectroscopia de Ressonância Magnética
Modelos Moleculares
RNA Catalítico/química
Especificidade por Substrato
Termodinâmica
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (RNA, Catalytic); EC 3.1.- (Endoribonucleases); EC 3.1.27.- (varkud satellite ribozyme)
[Em] Mês de entrada:1706
[Cu] Atualização por classe:170605
[Lr] Data última revisão:
170605
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160512
[St] Status:MEDLINE
[do] DOI:10.1093/nar/gkw401



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