Base de dados : MEDLINE
Pesquisa : B01.300.381.075 [Categoria DeCS]
Referências encontradas : 2063 [refinar]
Mostrando: 1 .. 10   no formato [Detalhado]

página 1 de 207 ir para página                         

  1 / 2063 MEDLINE  
              next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:29217480
[Au] Autor:Aichinger G; Puntscher H; Beisl J; Kütt ML; Warth B; Marko D
[Ad] Endereço:Department of Food Chemistry and Toxicology, Faculty of Chemistry, University of Vienna, Waehringerstr. 38, A-1090 Vienna, Austria.
[Ti] Título:Delphinidin protects colon carcinoma cells against the genotoxic effects of the mycotoxin altertoxin II.
[So] Source:Toxicol Lett;284:136-142, 2018 Mar 01.
[Is] ISSN:1879-3169
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:Alternaria spp. are ubiquitous molds that are able to produce toxic secondary metabolites which may contaminate food globally. One of those is the mycotoxin altertoxin II (ATX-II), a genotoxic and mutagenic compound. In recent years, different flavonoids that may co-occur with mycotoxins in food were demonstrated to temper toxic effects of molds, mostly through their anti-oxidant properties. Thus, in this study, we assessed the influence of the berry anthocyanidin delphinidin on the toxicity of ATX-II in HT-29 colon carcinoma cells. We performed coupled SRB/WST-1 cytotoxicity assays which revealed only weak antagonistic interactions, and single-cell gel electrophoresis ("comet") assays, where we observed a potent protective effect of delphinidin on the DNA-damaging properties of ATX-II. Furthermore, we investigated the mechanism for this interaction. In the DCF assay delphinidin was found to reduce intracellular oxidative stress levels, which might contribute partly to the latter protection. However, LC-MS experiments showed that co-incubation of the mycotoxin with either delphinidin or its potential degradation product phloroglucinol aldehyde significantly decreased ATX-II concentrations in aqueous solutions, indicating that a direct chemical reaction of ATX-II with these components is likely responsible for the observed loss of toxicity. Our results indicate that delphinidin - and possibly other anthocyanins as well - might play a role in the protection of the gut from Alternaria-induced genotoxicity.
[Mh] Termos MeSH primário: Antocianinas/farmacologia
Antioxidantes/farmacologia
Benzo(a)Antracenos/toxicidade
Dano ao DNA/efeitos dos fármacos
Mutagênicos/toxicidade
[Mh] Termos MeSH secundário: Alternaria/crescimento & desenvolvimento
Alternaria/metabolismo
Benzo(a)Antracenos/isolamento & purificação
Contagem de Células
Técnicas de Cultura de Células
Sobrevivência Celular/efeitos dos fármacos
Ensaio Cometa
Relação Dose-Resposta a Droga
Microbiologia de Alimentos
Células HT29
Seres Humanos
Estrutura Molecular
Mutagênicos/isolamento & purificação
Estresse Oxidativo/efeitos dos fármacos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Anthocyanins); 0 (Antioxidants); 0 (Benz(a)Anthracenes); 0 (Mutagens); 56257-59-1 (altertoxin II); EM6MD4AEHE (delphinidin)
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180221
[Lr] Data última revisão:
180221
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171209
[St] Status:MEDLINE


  2 / 2063 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:29262712
[Au] Autor:Mbovane MS; Gangireddygari VSR; Nyoni H; Ntushelo K
[Ad] Endereço:1 Department of Agriculture and Animal Health, University of South Africa , Florida, 1710 South Africa.
[Ti] Título:Acetaldehyde suppresses growth, changes conidia morphology and reduces the production of adenosine 3',5'-cyclic monophosphate in a dose dependent manner in Alternaria alternata.
[So] Source:Acta Biol Hung;68(4):490-492, 2017 Dec.
[Is] ISSN:0236-5383
[Cp] País de publicação:Hungary
[La] Idioma:eng
[Ab] Resumo:One-day-old cultures of the plant pathogenic fungus Alternaria alternata were exposed to 0%, 5% and 10% acetaldehyde mixed with distilled water. Fungal growth data showed that, overall, the 5% and the 10% acetaldehyde treatments significantly inhibited the growth of A. alternata, and that acetyldehyde also facilitated maturity and multicellularity of fungal conidia. The increase of the acetyldehyde dose also caused correlated decrease of adenosine 3',5'-cyclic monophosphate produced by A. alternata.
[Mh] Termos MeSH primário: Acetaldeído/farmacologia
Alternaria/fisiologia
AMP Cíclico/metabolismo
Esporos Fúngicos/crescimento & desenvolvimento
[Mh] Termos MeSH secundário: Alternaria/citologia
Relação Dose-Resposta a Droga
Esporos Fúngicos/citologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
E0399OZS9N (Cyclic AMP); GO1N1ZPR3B (Acetaldehyde)
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180216
[Lr] Data última revisão:
180216
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171222
[St] Status:MEDLINE
[do] DOI:10.1556/018.68.2017.4.13


  3 / 2063 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
[PMID]:29369560
[Au] Autor:Vetchinkina EM; Komakhina VV; Vysotskii DA; Zaitsev DV; Smirnov AN; Babakov AV; Komakhin RA
[Ti] Título:[Expression of plant antimicrobial peptide pro-SmAMP2 gene increases resistance of transgenic potato plants to Alternaria and Fusarium pathogens].
[So] Source:Genetika;52(9):1055-68, 2016 Sep.
[Is] ISSN:0016-6758
[Cp] País de publicação:Russia (Federation)
[La] Idioma:rus
[Ab] Resumo:The chickweed (Stellaria media L.) pro-SmAMP2 gene encodes the hevein-like peptides that have in vitro antimicrobial activity against certain harmful microorganisms. These peptides play an important role in protecting the chickweed plants from infection, and the pro-SmAMP2 gene was previously used to protect transgenic tobacco and Arabidopsis plants from phytopathogens. In this study, the pro-SmAMP2 gene under control of viral CaMV35S promoter or under control of its own pro-SmAMP2 promoter was transformed into cultivated potato plants of two cultivars, differing in the resistance to Alternaria: Yubiley Zhukova (resistant) and Skoroplodny (susceptible). With the help of quantitative real-time PCR, it was demonstrated that transgenic potato plants expressed the pro-SmAMP2 gene under control of both promoters at the level comparable to or exceeding the level of the potato actin gene. Assessment of the immune status of the transformants demonstrated that expression of antimicrobial peptide pro-SmAMP2 gene was able to increase the resistance to a complex of Alternaria sp. and Fusarium sp. phytopathogens only in potato plants of the Yubiley Zhukova cultivar. The possible role of the pro-SmAMP2 products in protecting potatoes from Alternaria sp. and Fusarium sp. is discussed.
[Mh] Termos MeSH primário: Alternaria
Peptídeos Catiônicos Antimicrobianos
Resistência à Doença/genética
Fusarium
Proteínas de Plantas
Plantas Geneticamente Modificadas
Solanum tuberosum
[Mh] Termos MeSH secundário: Peptídeos Catiônicos Antimicrobianos/biossíntese
Peptídeos Catiônicos Antimicrobianos/genética
Proteínas de Plantas/biossíntese
Proteínas de Plantas/genética
Plantas Geneticamente Modificadas/genética
Plantas Geneticamente Modificadas/metabolismo
Plantas Geneticamente Modificadas/microbiologia
Solanum tuberosum/genética
Solanum tuberosum/metabolismo
Solanum tuberosum/microbiologia
Stellaria/genética
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Antimicrobial Cationic Peptides); 0 (Plant Proteins)
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180205
[Lr] Data última revisão:
180205
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180126
[St] Status:MEDLINE


  4 / 2063 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:29045903
[Au] Autor:Osbourn M; Soares DC; Vacca F; Cohen ES; Scott IC; Gregory WF; Smyth DJ; Toivakka M; Kemter AM; le Bihan T; Wear M; Hoving D; Filbey KJ; Hewitson JP; Henderson H; Gonzàlez-Cìscar A; Errington C; Vermeren S; Astier AL; Wallace WA; Schwarze J; Ivens AC; Maizels RM; McSorley HJ
[Ad] Endereço:MRC Centre for Inflammation Research, University of Edinburgh, Queen's Medical Research Institute, 47 Little France Crescent, Edinburgh EH16 4TJ, UK.
[Ti] Título:HpARI Protein Secreted by a Helminth Parasite Suppresses Interleukin-33.
[So] Source:Immunity;47(4):739-751.e5, 2017 Oct 17.
[Is] ISSN:1097-4180
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Infection by helminth parasites is associated with amelioration of allergic reactivity, but mechanistic insights into this association are lacking. Products secreted by the mouse parasite Heligmosomoides polygyrus suppress type 2 (allergic) immune responses through interference in the interleukin-33 (IL-33) pathway. Here, we identified H. polygyrus Alarmin Release Inhibitor (HpARI), an IL-33-suppressive 26-kDa protein, containing three predicted complement control protein (CCP) modules. In vivo, recombinant HpARI abrogated IL-33, group 2 innate lymphoid cell (ILC2) and eosinophilic responses to Alternaria allergen administration, and diminished eosinophilic responses to Nippostrongylus brasiliensis, increasing parasite burden. HpARI bound directly to both mouse and human IL-33 (in the cytokine's activated state) and also to nuclear DNA via its N-terminal CCP module pair (CCP1/2), tethering active IL-33 within necrotic cells, preventing its release, and forestalling initiation of type 2 allergic responses. Thus, HpARI employs a novel molecular strategy to suppress type 2 immunity in both infection and allergy.
[Mh] Termos MeSH primário: Proteínas de Helminto/imunologia
Interleucina-33/imunologia
Nematospiroides dubius/imunologia
Infecções por Strongylida/imunologia
[Mh] Termos MeSH secundário: Alérgenos/imunologia
Alternaria/imunologia
Sequência de Aminoácidos
Animais
Western Blotting
Eosinófilos/imunologia
Proteínas de Helminto/genética
Proteínas de Helminto/metabolismo
Interações Hospedeiro-Parasita/imunologia
Seres Humanos
Imunidade Inata/imunologia
Interleucina-33/genética
Interleucina-33/metabolismo
Linfócitos/imunologia
Camundongos Endogâmicos BALB C
Camundongos Endogâmicos C57BL
Camundongos Knockout
Nematospiroides dubius/genética
Nematospiroides dubius/metabolismo
Ligação Proteica/imunologia
Receptores de Interleucina/imunologia
Receptores de Interleucina/metabolismo
Homologia de Sequência de Aminoácidos
Infecções por Strongylida/metabolismo
Infecções por Strongylida/parasitologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Allergens); 0 (Helminth Proteins); 0 (Interleukin-33); 0 (Receptors, Interleukin); 0 (interleukin-33 receptor, mouse)
[Em] Mês de entrada:1711
[Cu] Atualização por classe:171106
[Lr] Data última revisão:
171106
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171019
[St] Status:MEDLINE


  5 / 2063 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28961818
[Au] Autor:Asari S; Ongena M; Debois D; De Pauw E; Chen K; Bejai S; Meijer J
[Ad] Endereço:Department of Plant Biology, Uppsala Biocenter, Linnéan Center for Plant Biology, Swedish University of Agricultural Sciences, S-75007 Uppsala, Sweden.
[Ti] Título:Insights into the molecular basis of biocontrol of Brassica pathogens by Bacillus amyloliquefaciens UCMB5113 lipopeptides.
[So] Source:Ann Bot;120(4):551-562, 2017 Oct 17.
[Is] ISSN:1095-8290
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Background and Aims: Certain micro-organisms can improve plant protection against pathogens. The protective effect may be direct, e.g. due to antibiotic compounds, or indirect, by priming of plant defence as induced systemic resistance (ISR). The plant growth-promoting rhizobacterium Bacillus amyloliquefaciens UCMB5113 shows potential for disease management of oilseed rape. To investigate the mode of action of this protection, especially in relation to jasmonic acid-dependent ISR, Bacillus UCMB5113 was tested with Arabidopsis thaliana mutants and several important fungal pathogens of Brassica species. Methods: Secreted lipopeptide fractions from Bacillus UCMB5113, together with synthetic peptide mimics, were evaluated for their effects on fungal phytopathogens and A. thaliana . The structures of secreted lipopeptides were analysed using mass spectrometry. Plant mutants and reporter lines were used to identify signalling steps involved in disease suppression by lipopeptides. Key Results: In plate tests Bacillus UCMB5113 and lipopeptide extracts suppressed growth of several fungal pathogens infecting Brassica plants. Separation of secreted lipopeptides using reversed-phase high-performance liquid chromatography revealed several fractions that inhibited fungal growth. Analysis by mass spectrometry identified the most potent compounds as novel linear forms of antifungal fengycins, with synthetic peptide mimics confirming the biological activity. Application of the lipopeptide extracts on Arabidopsis roots provided systemic protection against Alternaria brassicicola on leaves. Arabidopsis signalling mutants and PDF1.2 and VSP2 promoter-driven GUS lines indicated that the lipopeptide fraction involved jasmonic-acid-dependent host responses for suppression of fungal growth indicative of ISR. Conclusions: The ability of Bacillus UCMB5113 to counteract pathogens using both antagonistic lipopeptides and through ISR provides a promising tool for sustainable crop production.
[Mh] Termos MeSH primário: Bacillus amyloliquefaciens/fisiologia
Brassica/microbiologia
Resistência à Doença/fisiologia
Lipopeptídeos/fisiologia
[Mh] Termos MeSH secundário: Alternaria/metabolismo
Antifúngicos/metabolismo
Arabidopsis/microbiologia
Arabidopsis/fisiologia
Bacillus amyloliquefaciens/metabolismo
Brassica/fisiologia
Interações Hospedeiro-Patógeno/fisiologia
Folhas de Planta/microbiologia
Folhas de Planta/fisiologia
Raízes de Plantas/microbiologia
Raízes de Plantas/fisiologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Antifungal Agents); 0 (Lipopeptides)
[Em] Mês de entrada:1711
[Cu] Atualização por classe:171109
[Lr] Data última revisão:
171109
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170930
[St] Status:MEDLINE
[do] DOI:10.1093/aob/mcx089


  6 / 2063 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28934298
[Au] Autor:Kan J; Liu T; Ma N; Li H; Li X; Wang J; Zhang B; Chang Y; Lin J
[Ad] Endereço:Institute of Horticulture, Jiangsu Academy of Agricultural Sciences/ Jiangsu Key Laboratory for Horticultural Crop Genetic improvement, Nanjing, China.
[Ti] Título:Transcriptome analysis of Callery pear (Pyrus calleryana) reveals a comprehensive signalling network in response to Alternaria alternata.
[So] Source:PLoS One;12(9):e0184988, 2017.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:The pear is an important temperate fruit worldwide that is produced by a group of species in the genus Pyrus. Callery pear (Pyrus calleryana Decne) is characterized by high resistance to multiple diseases, good adaptability, and high ornamental value, and is therefore widely planted in pear orchards for edible fruit production or as stock. Plant pathogens are a major threat to pear yield. Black spot disease, caused by the filamentous fungus Alternaria alternata, is one of the most serious diseases in pear. Elucidation of resistant genes to black spot disease is extremely important for understanding the underlying mechanisms as well as for the development of resistant cultivars. In this study, high-throughput single-strand RNA-sequencing was used to compare the transcriptome profiles of Callery pear leaves before and after A. alternata incubation for 7 days. The analysis yielded 73.3 Gb of clean data that were mapped onto the reference genome of the Chinese pear, and differentially expressed gene(DEG)s were identified with |log2FC| ≥ 1. Functional annotation demonstrated that black spot disease promoted great changes in the overall metabolism, and enrichment analysis of gene ontology terms showed that most of them are closely linked to signalling network and photosynthesis. Specifically, the genes included mainly transcription factors and genes involved in calcium signalling and ethylene and jasmonate pathways. Eight members of the ethylene response factor transcription factor gene family Group IX, including ERF1, ERF7, and ERF105, were up-regulated to 2.03-3.37-fold compared with CK, suggesting their role in the defence response to pathogen infection. Additionally, multiple transcription factors involved in biotic stresses, such as NAC78, NAC2, MYB44, and bHLH28, were up-regulated. Furthermore, we identified 144 long non-coding (lnc)RNAs, providing new insight into the involvement of lncRNAs in the response to black spot disease. Our study provides valuable data on the molecular genetics and functional genomic mechanisms of resistance to black spot disease in Callery pear. A good understanding of the molecular response to this disease will allow the development of durable and environmentally friendly control strategies.
[Mh] Termos MeSH primário: Alternaria/patogenicidade
Perfilação da Expressão Gênica
Regulação da Expressão Gênica de Plantas
Redes Reguladoras de Genes
Doenças das Plantas/genética
Proteínas de Plantas/genética
Pyrus/genética
[Mh] Termos MeSH secundário: Sequenciamento de Nucleotídeos em Larga Escala
Doenças das Plantas/microbiologia
Pyrus/microbiologia
Transcriptoma
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Plant Proteins)
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171017
[Lr] Data última revisão:
171017
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170922
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0184988


  7 / 2063 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28891001
[Au] Autor:Xiang J; Fu M; Hong N; Zhai L; Xiao F; Wang G
[Ad] Endereço:State Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University, Wuhan, 430070, Hubei, China.
[Ti] Título:Characterization of a novel botybirnavirus isolated from a phytopathogenic Alternaria fungus.
[So] Source:Arch Virol;162(12):3907-3911, 2017 Dec.
[Is] ISSN:1432-8798
[Cp] País de publicação:Austria
[La] Idioma:eng
[Ab] Resumo:Alternaria fungi are important pathogens infecting a wide variety of organisms. Here, we report a novel double-stranded RNA (dsRNA) mycovirus named Alternaria botybirnavirus 1 (ABRV1) isolated from a phytopathogenic Alternaria sp. strain (SCFS-3) infecting a pear tree in China. ABRV1 has two dsRNA components (dsRNAs 1 and 2) with the sizes of 6,188 and 5,903 bp, containing two putative open reading frames encoding two polyproteins (202 and 192 kDa, respectively). The polyprotein encoded by ABRV1 dsRNA1 shares 41% amino acid (aa) sequence identity with the one encoded by dsRNA2 (instead of dsRNA1) of Sclerotinia sclerotiorum botybirnavirus 1 (SsBRV1). Conversely, the polyprotein encoded by ABRV1 dsRNA2 shares 46% aa sequence identity with the one (i.e., cap-pol fusion protein) encoded by SsBRV1 dsRNA1. ABRV1 has isometric spherical virus particles (~40 nm in diameter), putatively composed of the 60-, 70- and 80-kDa structural proteins. The genomic organization and phylogenetic analyses revealed that ABRV1 belongs to a newly proposed family "Botybirnaviridae", and to our knowledge, this is the first report of a botybirnavirus infecting an Alternaria sp. strain.
[Mh] Termos MeSH primário: Alternaria/virologia
Micovírus/classificação
Micovírus/isolamento & purificação
Vírus de RNA/classificação
Vírus de RNA/isolamento & purificação
[Mh] Termos MeSH secundário: China
Micovírus/genética
Ordem dos Genes
Genoma Viral
Peso Molecular
Fases de Leitura Aberta
Filogenia
Pyrus/microbiologia
Vírus de RNA/genética
RNA de Cadeia Dupla/genética
RNA Viral/genética
Análise de Sequência de DNA
Homologia de Sequência de Aminoácidos
Proteínas Virais/química
Proteínas Virais/genética
Vírion/química
Vírion/ultraestrutura
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (RNA, Double-Stranded); 0 (RNA, Viral); 0 (Viral Proteins)
[Em] Mês de entrada:1711
[Cu] Atualização por classe:171113
[Lr] Data última revisão:
171113
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170912
[St] Status:MEDLINE
[do] DOI:10.1007/s00705-017-3543-6


  8 / 2063 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28880897
[Au] Autor:Tian H; Wang H; Hui X; Wang Z; Drijber RA; Liu J
[Ad] Endereço:Key Laboratory of Plant Nutrition and Agro-environment in Northwest China, Ministry of Agriculture/College of Natural Resources and Environment, Northwest A&F University, Yangling, Shaanxi, China.
[Ti] Título:Changes in soil microbial communities after 10 years of winter wheat cultivation versus fallow in an organic-poor soil in the Loess Plateau of China.
[So] Source:PLoS One;12(9):e0184223, 2017.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Agricultural management methods, such as cultivation or fallowing, have led to significant changes in soil fertility and hence, crop yield. Such changes may have stemmed from changes in soil microbial communities and associated biogeochemical processes. This phenomenon is particularly true in organic-poor soil in the Loess Plateau of China. In this study, we examined three existing soil management regimes as part of a 10-year field experiment and evaluated their effects on fungal and bacterial community structures by performing high-throughput 454 pyrosequencing. These management regimes were (i) fertilized winter wheat (Triticum aestivum L.) (FW), (ii) continuous natural fallow with weeds but without crop grown (NF), and (iii) continuous bare fallow without weeds or crop grown (BF). After 10 years, soil organic carbon (SOC), microbial biomass carbon (MBC), and available potassium (K) concentrations were highest in NF. Soil N behaved differently, with BF obtaining the highest nitrate nitrogen (N). Meanwhile, slight differences in total N (TN) were observed among FW, NF, and BF. Available phosphorus (P) was highest and available K was lowest in FW. Microbial communities were dominated by Ascomycota (59.1% of fungal sequences), and Acidobacteria, Actinobacteria, Bacteroidetes, Firmicutes, and Proteobacteria (75.7% of bacterial sequences) in FW, NF and BF at the phylum level. Soil management regimes did not affect the fungal and bacterial richness and diversity but significantly modified their community compositions. Compared with FW, the abundances of Ascomycota (fungi phylum) and Alternaria, Gibberella, and Emericella (fungi genus) were increased by NF, whereas the values of Chaetomium, Humicola, and Cryptococcus (fungi genus) were decreased by BF. The abundances of Verrucomicrobia (bacteria phylum), and Steroidobacter (bacteria genus) were increased by NF, and Bacteroides (bacteria genus) was increased by BF. Canonical correspondence analysis showed that SOC, available P, and TN might be the key factors in community formation. Therefore, the decadal absence of plants (BF) affected soil fertility by increased available K and nitrate N, whileas natural fallow (NF) affected soil fertility by increased SOC, available K, and MBC, and they all changed fungal and bacterial community compositions.
[Mh] Termos MeSH primário: Microbiologia do Solo
Solo/classificação
Triticum
[Mh] Termos MeSH secundário: Alternaria/isolamento & purificação
Ascomicetos/isolamento & purificação
Biomassa
Carbono
Chaetomium/isolamento & purificação
China
Cryptococcus/isolamento & purificação
Emericella/isolamento & purificação
Gibberella/isolamento & purificação
Nitrogênio/análise
Potássio/análise
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Soil); 7440-44-0 (Carbon); N762921K75 (Nitrogen); RWP5GA015D (Potassium)
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171116
[Lr] Data última revisão:
171116
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170908
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0184223


  9 / 2063 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28848100
[Au] Autor:Wang J; Wu Y; Li J; Huang X; Zhu R
[Ad] Endereço:Department of Allergy, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
[Ti] Título:Eight Aeroallergen Skin Extracts May Be the Optimal Panel for Allergic Rhinitis Patients in Central China.
[So] Source:Int Arch Allergy Immunol;173(4):193-198, 2017.
[Is] ISSN:1423-0097
[Cp] País de publicação:Switzerland
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: The prevalence of allergic rhinitis (AR) is increasing rapidly in Central China. The skin prick test (SPT) is the standard tool with which to determine the allergen sensitization status in AR patients. Changes in allergen sensitization patterns have been observed within countries and regions due to geographical and seasonal variations. OBJECTIVE: The aim of this study was to evaluate the profile of SPT reactivity to different aeroallergens in AR patients and to suggest a minimal panel of allergens to detect sensitized patients in Central China. METHODS: From January 2015 to December 2016, patients who presented to Tongji Hospital with suspected AR were tested with the same panel of 19 aeroallergens. The results of SPT were analyzed to determine the minimum test battery panel necessary to cover 99% of the cases of SPT sensitization in different age subgroups. RESULTS: A total of 2,416 patients (male:female ratio 1.2:1) were enrolled in our study with an average age of 22.0 years. The overall rate of sensitization to any allergen was 79.0%, and 64.3% of the subjects were monosensitized. The highest sensitized rate was found in the subgroup aged 14-18 years (92.0%), followed by the subgroups of 6-14 years (86.4%), >18 years (75.6%), and ≤6 years (74.9%). The most common sensitization was to Dermatophagoides farinae (71.1%). Testing with 8 allergens (D. pteronyssinus, D. farinae, Platanus, Artemisia, Cryptomeria, Blatella germanica, Humulus, and Alternaria) was sufficient to identify over 99% of the sensitized patients. CONCLUSION: An SPT panel covering 8 allergen extracts was able to detect almost all sensitized patients suffering from AR symptoms in Central China.
[Mh] Termos MeSH primário: Alérgenos/imunologia
Rinite Alérgica/diagnóstico
Testes Cutâneos
[Mh] Termos MeSH secundário: Adolescente
Adulto
Idoso
Idoso de 80 Anos ou mais
Poluentes Atmosféricos/imunologia
Alternaria/imunologia
Animais
Antígenos de Dermatophagoides/imunologia
Antígenos de Fungos/imunologia
Antígenos de Plantas/imunologia
Criança
Pré-Escolar
China
Baratas/imunologia
Dermatophagoides farinae/imunologia
Dermatophagoides pteronyssinus/imunologia
Feminino
Seres Humanos
Lactente
Proteínas de Insetos/imunologia
Magnoliopsida/imunologia
Masculino
Meia-Idade
Rinite Alérgica/imunologia
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Air Pollutants); 0 (Allergens); 0 (Antigens, Dermatophagoides); 0 (Antigens, Fungal); 0 (Antigens, Plant); 0 (Insect Proteins)
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171116
[Lr] Data última revisão:
171116
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170830
[St] Status:MEDLINE
[do] DOI:10.1159/000479429


  10 / 2063 MEDLINE  
              first record previous record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28836786
[Au] Autor:Shi ZZ; Miao FP; Fang ST; Liu XH; Yin XL; Ji NY
[Ad] Endereço:Yantai Institute of Coastal Zone Research, Chinese Academy of Sciences , Yantai 264003, China.
[Ti] Título:Sesteralterin and Tricycloalterfurenes A-D: Terpenes with Rarely Occurring Frameworks from the Marine-Alga-Epiphytic Fungus Alternaria alternata k21-1.
[So] Source:J Nat Prod;80(9):2524-2529, 2017 Sep 22.
[Is] ISSN:1520-6025
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:A new sesterterpene, sesteralterin (1), four new meroterpenes, tricycloalterfurenes A-D (2-5), and a known meroterpene, TCA-F (6), were obtained from the culture extract of an Alternaria alternata strain (k21-1) isolated from the surface of the marine red alga Lomentaria hakodatensis. The structures and relative/absolute configurations of these compounds were identified by spectroscopic analyses, mainly including 1D/2D NMR, ECD, and mass spectra and quantum chemical calculations. Compound 1 represents the first nitidasane sesterterpene naturally produced by fungi, and 2-5 feature a tetrahydrofuran unit rarely occurring in tricycloalternarenes. Compounds 1-6 were assayed for inhibition of the growth of four marine plankton and one marine alga-pathogenic bacterium.
[Mh] Termos MeSH primário: Alternaria/química
Furanos/isolamento & purificação
Furanos/farmacologia
Compostos Heterocíclicos com 3 Anéis/isolamento & purificação
Compostos Heterocíclicos com 3 Anéis/farmacologia
Terpenos/isolamento & purificação
Terpenos/farmacologia
[Mh] Termos MeSH secundário: Furanos/química
Compostos Heterocíclicos com 3 Anéis/química
Espectroscopia de Ressonância Magnética
Biologia Marinha
Estrutura Molecular
Terpenos/química
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Furans); 0 (Heterocyclic Compounds, 3-Ring); 0 (Terpenes); 0 (sesteralterin); 0 (tricycloalterfurene B)
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171031
[Lr] Data última revisão:
171031
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170825
[St] Status:MEDLINE
[do] DOI:10.1021/acs.jnatprod.7b00478



página 1 de 207 ir para página                         
   


Refinar a pesquisa
  Base de dados : MEDLINE Formulário avançado   

    Pesquisar no campo  
1  
2
3
 
           



Search engine: iAH v2.6 powered by WWWISIS

BIREME/OPAS/OMS - Centro Latino-Americano e do Caribe de Informação em Ciências da Saúde