Base de dados : MEDLINE
Pesquisa : B01.650.232.200 [Categoria DeCS]
Referências encontradas : 54 [refinar]
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  1 / 54 MEDLINE  
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[PMID]:28069893
[Au] Autor:Kurotani A; Yamada Y; Sakurai T
[Ad] Endereço:RIKEN Center for Sustainable Resource Science, Suehiro, Tsurumi, Yokohama, Kanagawa, Japan.
[Ti] Título:Alga-PrAS (Algal Protein Annotation Suite): A Database of Comprehensive Annotation in Algal Proteomes.
[So] Source:Plant Cell Physiol;58(1):e6, 2017 01 01.
[Is] ISSN:1471-9053
[Cp] País de publicação:Japan
[La] Idioma:eng
[Ab] Resumo:Algae are smaller organisms than land plants and offer clear advantages in research over terrestrial species in terms of rapid production, short generation time and varied commercial applications. Thus, studies investigating the practical development of effective algal production are important and will improve our understanding of both aquatic and terrestrial plants. In this study we estimated multiple physicochemical and secondary structural properties of protein sequences, the predicted presence of post-translational modification (PTM) sites, and subcellular localization using a total of 510,123 protein sequences from the proteomes of 31 algal and three plant species. Algal species were broadly selected from green and red algae, glaucophytes, oomycetes, diatoms and other microalgal groups. The results were deposited in the Algal Protein Annotation Suite database (Alga-PrAS; http://alga-pras.riken.jp/), which can be freely accessed online.
[Mh] Termos MeSH primário: Proteínas de Algas/metabolismo
Bases de Dados de Proteínas
Microalgas/metabolismo
Proteoma/metabolismo
[Mh] Termos MeSH secundário: Proteínas de Algas/classificação
Clorófitas/classificação
Clorófitas/metabolismo
Análise por Conglomerados
Biologia Computacional/métodos
Cyanophora/metabolismo
Diatomáceas/classificação
Diatomáceas/metabolismo
Internet
Microalgas/classificação
Oomicetos/classificação
Oomicetos/metabolismo
Proteínas de Plantas/classificação
Proteínas de Plantas/metabolismo
Plantas/classificação
Plantas/metabolismo
Rodófitas/classificação
Rodófitas/metabolismo
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Algal Proteins); 0 (Plant Proteins); 0 (Proteome)
[Em] Mês de entrada:1707
[Cu] Atualização por classe:170723
[Lr] Data última revisão:
170723
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170111
[St] Status:MEDLINE
[do] DOI:10.1093/pcp/pcw212


  2 / 54 MEDLINE  
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[PMID]:27502278
[Au] Autor:Kojima S; Muramoto K; Kusano T
[Ad] Endereço:From the Frontier Research Institute for Interdisciplinary Sciences, Tohoku University, Sendai 980-8578, Japan and Graduate School of Life Sciences, Tohoku University, Sendai 980-8577, Japan skojima0801@gmail.com.
[Ti] Título:Outer Membrane Proteins Derived from Non-cyanobacterial Lineage Cover the Peptidoglycan of Cyanophora paradoxa Cyanelles and Serve as a Cyanelle Diffusion Channel.
[So] Source:J Biol Chem;291(38):20198-209, 2016 Sep 16.
[Is] ISSN:1083-351X
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:The cyanelle is a primitive chloroplast that contains a peptidoglycan layer between its inner and outer membranes. Despite the fact that the envelope structure of the cyanelle is reminiscent of Gram-negative bacteria, the Cyanophora paradoxa genome appears to lack genes encoding homologs of putative peptidoglycan-associated outer membrane proteins and outer membrane channels. These are key components of Gram-negative bacterial membranes, maintaining structural stability and regulating permeability of outer membrane, respectively. Here, we discovered and characterized two dominant peptidoglycan-associated outer membrane proteins of the cyanelle (∼2 × 10(6) molecules per cyanelle). We named these proteins CppF and CppS (cyanelle peptidoglycan-associated proteins). They are homologous to each other and function as a diffusion channel that allows the permeation of compounds with Mr <1,000 as revealed by permeability measurements using proteoliposomes reconstituted with purified CppS and CppF. Unexpectedly, amino acid sequence analysis revealed no evolutionary linkage to cyanobacteria, showing only a moderate similarity to cell surface proteins of bacteria belonging to Planctomycetes phylum. Our findings suggest that the C. paradoxa cyanelle adopted non-cyanobacterial lineage proteins as its main outer membrane components, providing a physical link with the underlying peptidoglycan layer and functioning as a diffusion route for various small substances across the outer membrane.
[Mh] Termos MeSH primário: Proteínas da Membrana Bacteriana Externa/metabolismo
Membrana Celular/metabolismo
Cyanophora/metabolismo
Peptidoglicano/metabolismo
[Mh] Termos MeSH secundário: Proteínas da Membrana Bacteriana Externa/genética
Membrana Celular/genética
Cyanophora/genética
Peptidoglicano/genética
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Bacterial Outer Membrane Proteins); 0 (Peptidoglycan)
[Em] Mês de entrada:1705
[Cu] Atualização por classe:170916
[Lr] Data última revisão:
170916
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160810
[St] Status:MEDLINE
[do] DOI:10.1074/jbc.M116.746131


  3 / 54 MEDLINE  
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[PMID]:27148492
[Au] Autor:Ball SG; Bhattacharya D; Qiu H; Weber AP
[Ad] Endereço:Unité de Glycobiologie Structurale et Fonctionnelle, UMR8576 Centre National de la Recherche Scientifique-Université des Sciences et Technologies de Lille Villeneuve d'Ascq, France.
[Ti] Título:Commentary: Plastid establishment did not require a chlamydial partner.
[So] Source:Front Cell Infect Microbiol;6:43, 2016.
[Is] ISSN:2235-2988
[Cp] País de publicação:Switzerland
[La] Idioma:eng
[Mh] Termos MeSH primário: Metabolismo dos Carboidratos/fisiologia
Chlamydia/genética
Cianobactérias/genética
Cyanophora/genética
Plastídeos/metabolismo
[Pt] Tipo de publicação:COMMENT; JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Em] Mês de entrada:1606
[Cu] Atualização por classe:160507
[Lr] Data última revisão:
160507
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160506
[St] Status:MEDLINE
[do] DOI:10.3389/fcimb.2016.00043


  4 / 54 MEDLINE  
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[PMID]:26439276
[Au] Autor:Takahashi T; Nishida T; Saito C; Yasuda H; Nozaki H
[Ad] Endereço:Department of Biological Sciences, Graduate School of Science, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-0033, Japan.
[Ti] Título:Ultra-high voltage electron microscopy of primitive algae illuminates 3D ultrastructures of the first photosynthetic eukaryote.
[So] Source:Sci Rep;5:14735, 2015 Oct 06.
[Is] ISSN:2045-2322
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:A heterotrophic organism 1-2 billion years ago enslaved a cyanobacterium to become the first photosynthetic eukaryote, and has diverged globally. The primary phototrophs, glaucophytes, are thought to retain ancestral features of the first photosynthetic eukaryote, but examining the protoplast ultrastructure has previously been problematic in the coccoid glaucophyte Glaucocystis due to its thick cell wall. Here, we examined the three-dimensional (3D) ultrastructure in two divergent species of Glaucocystis using ultra-high voltage electron microscopy. Three-dimensional modelling of Glaucocystis cells using electron tomography clearly showed that numerous, leaflet-like flattened vesicles are distributed throughout the protoplast periphery just underneath a single-layered plasma membrane. This 3D feature is essentially identical to that of another glaucophyte genus Cyanophora, as well as the secondary phototrophs in Alveolata. Thus, the common ancestor of glaucophytes and/or the first photosynthetic eukaryote may have shown similar 3D structures.
[Mh] Termos MeSH primário: Cyanophora/ultraestrutura
Imagem Tridimensional/métodos
Microscopia Eletrônica de Transmissão/métodos
Fotossíntese/fisiologia
Plastídeos/ultraestrutura
[Mh] Termos MeSH secundário: Cyanophora/química
Plastídeos/química
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Em] Mês de entrada:1608
[Cu] Atualização por classe:151020
[Lr] Data última revisão:
151020
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:151007
[St] Status:MEDLINE
[do] DOI:10.1038/srep14735


  5 / 54 MEDLINE  
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[PMID]:25758953
[Au] Autor:Domman D; Horn M; Embley TM; Williams TA
[Ad] Endereço:Department of Microbiology and Ecosystem Science, University of Vienna, A-1090 Vienna, Austria.
[Ti] Título:Plastid establishment did not require a chlamydial partner.
[So] Source:Nat Commun;6:6421, 2015 Mar 11.
[Is] ISSN:2041-1723
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Primary plastids descend from the cyanobacterial endosymbiont of an ancient eukaryotic host, but the initial selective drivers that stabilized the association between these two cells are still unclear. One hypothesis that has achieved recent prominence suggests that the first role of the cyanobiont was in energy provision for a host cell whose reserves were being depleted by an intracellular chlamydial pathogen. A pivotal claim is that it was chlamydial proteins themselves that converted otherwise unusable cyanobacterial metabolites into host energy stores. We test this hypothesis by investigating the origins of the key enzymes using sophisticated phylogenetics. Here we show a mosaic origin for the relevant pathway combining genes with host, cyanobacterial or bacterial ancestry, but we detect no strong case for Chlamydiae to host transfer under the best-fitting models. Our conclusion is that there is no compelling evidence from gene trees that Chlamydiae played any role in establishing the primary plastid endosymbiosis.
[Mh] Termos MeSH primário: Metabolismo dos Carboidratos/fisiologia
Chlamydia/genética
Cianobactérias/genética
Cyanophora/genética
Plastídeos/metabolismo
[Mh] Termos MeSH secundário: Proteínas de Bactérias/genética
Proteínas de Bactérias/metabolismo
Teorema de Bayes
Evolução Biológica
Chlamydia/classificação
Chlamydia/metabolismo
Cianobactérias/classificação
Cianobactérias/metabolismo
Cyanophora/classificação
Cyanophora/metabolismo
Transferência Genética Horizontal
Proteínas de Membrana Transportadoras/genética
Proteínas de Membrana Transportadoras/metabolismo
Filogenia
Plastídeos/genética
Simbiose/fisiologia
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Bacterial Proteins); 0 (Membrane Transport Proteins); 142845-21-4 (uhpC protein, bacteria)
[Em] Mês de entrada:1602
[Cu] Atualização por classe:170922
[Lr] Data última revisão:
170922
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:150312
[St] Status:MEDLINE
[do] DOI:10.1038/ncomms7421


  6 / 54 MEDLINE  
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[PMID]:25281844
[Au] Autor:Jackson CJ; Reyes-Prieto A
[Ad] Endereço:Department of Biology, University of New Brunswick, Fredericton, New Brunswick, Canada.
[Ti] Título:The mitochondrial genomes of the glaucophytes Gloeochaete wittrockiana and Cyanoptyche gloeocystis: multilocus phylogenetics suggests a monophyletic archaeplastida.
[So] Source:Genome Biol Evol;6(10):2774-85, 2014 Oct 03.
[Is] ISSN:1759-6653
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:A significant limitation when testing the putative single origin of primary plastids and the monophyly of the Archaeplastida supergroup, comprised of the red algae, viridiplants, and glaucophytes, is the scarce nuclear and organellar genome data available from the latter lineage. The Glaucophyta are a key algal group when investigating the origin and early diversification of photosynthetic eukaryotes. However, so far only the plastid and mitochondrial genomes of the glaucophytes Cyanophora paradoxa (strain CCMP 329) and Glaucocystis nostochinearum (strain UTEX 64) have been completely sequenced. Here, we present the complete mitochondrial genomes of Gloeochaete wittrockiana SAG 46.84 (36.05 kb; 33 protein-coding genes, 6 unidentified open reading frames [ORFs], and 28 transfer RNAs [tRNAs]) and Cyanoptyche gloeocystis SAG 4.97 (33.24 kb; 33 protein-coding genes, 6 unidentified ORFs, and 26 tRNAs), which represent two genera distantly related to the "well-known" Cyanophora and Glaucocystis. The mitochondrial gene repertoire of the four glaucophyte species is highly conserved, whereas the gene order shows considerable variation. Phylogenetic analyses of 14 mitochondrial genes from representative taxa from the major eukaryotic supergroups, here including novel sequences from the glaucophytes Cyanophora tetracyanea (strain NIES-764) and Cyanophora biloba (strain UTEX LB 2766), recover a clade uniting the three Archaeplastida lineages; this recovery is dependent on our novel glaucophyte data, demonstrating the importance of greater taxon sampling within the glaucophytes.
[Mh] Termos MeSH primário: Cyanophora/genética
Genoma Mitocondrial/genética
[Mh] Termos MeSH secundário: Fases de Leitura Aberta/genética
Filogenia
RNA de Transferência/genética
[Pt] Tipo de publicação:LETTER; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
9014-25-9 (RNA, Transfer)
[Em] Mês de entrada:1507
[Cu] Atualização por classe:170220
[Lr] Data última revisão:
170220
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:141005
[St] Status:MEDLINE
[do] DOI:10.1093/gbe/evu218


  7 / 54 MEDLINE  
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[PMID]:25063443
[Au] Autor:Cai X; Wang X; Clapham DE
[Ad] Endereço:Division of Endocrinology, Metabolism and Nutrition, Department of Medicine, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ caixinj@gmail.com dclapham@enders.tch.harvard.edu.
[Ti] Título:Early evolution of the eukaryotic Ca2+ signaling machinery: conservation of the CatSper channel complex.
[So] Source:Mol Biol Evol;31(10):2735-40, 2014 Oct.
[Is] ISSN:1537-1719
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Calcium signaling is one of the most extensively employed signal transduction mechanisms in life. As life evolved into increasingly complex organisms, Ca(2+) acquired more extensive and varied functions. Here, we compare genes encoding proteins that govern Ca(2+) entry and exit across cells or organelles within organisms of early eukaryotic evolution into fungi, plants, and animals. Recent phylogenomics analyses reveal a complex Ca(2+) signaling machinery in the apusozoan protist Thecamonas trahens, a putative unicellular progenitor of Opisthokonta. We compare T. trahens Ca(2+) signaling to that in a marine bikont protist, Aurantiochytrium limacinum, and demonstrate the conservation of key Ca(2+) signaling molecules in the basally diverging alga Cyanophora paradoxa. Particularly, our findings reveal the conservation of the CatSper channel complex in Au. limacinum and C. paradoxa, suggesting that the CatSper complex likely originated from an ancestral Ca(2+) signaling machinery at the root of early eukaryotic evolution prior to the unikont/bikont split.
[Mh] Termos MeSH primário: Canais de Cálcio/genética
Sinalização do Cálcio
Eucariotos/genética
Evolução Molecular
[Mh] Termos MeSH secundário: Cyanophora/genética
Cyanophora/metabolismo
Eucariotos/classificação
Eucariotos/metabolismo
Filogenia
[Pt] Tipo de publicação:COMPARATIVE STUDY; LETTER; RESEARCH SUPPORT, U.S. GOV'T, NON-P.H.S.
[Nm] Nome de substância:
0 (Calcium Channels)
[Em] Mês de entrada:1506
[Cu] Atualização por classe:170922
[Lr] Data última revisão:
170922
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:140727
[St] Status:MEDLINE
[do] DOI:10.1093/molbev/msu218


  8 / 54 MEDLINE  
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[PMID]:25017510
[Au] Autor:Smith DR; Jackson CJ; Reyes-Prieto A
[Ad] Endereço:Department of Biology, University of Western Ontario, London, ON N6A 5B7, Canada. Electronic address: dsmit242@uwo.ca.
[Ti] Título:Nucleotide substitution analyses of the glaucophyte Cyanophora suggest an ancestrally lower mutation rate in plastid vs mitochondrial DNA for the Archaeplastida.
[So] Source:Mol Phylogenet Evol;79:380-4, 2014 Oct.
[Is] ISSN:1095-9513
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:A lot is known about the evolution and architecture of plastid, mitochondrial, and nuclear genomes, but surprisingly little is known about their relative rates of mutation. Most available relative-rate data come from seed plants, which, with few exceptions, have a mitochondrial mutation rate that is lower than those of the plastid and nucleus. But new findings from diverse plastid-bearing lineages have shown that for some eukaryotes the mitochondrial mutation rate is an order of magnitude greater than those of the plastid and nucleus. Here, we explore for the first time relative rates of mutation within the Glaucophyta-one of three main lineages that make up the Archaeplastida (or Plantae sensu lato). Nucleotide substitution analyses from distinct isolates of the unicellular glaucophyte Cyanophora paradoxa reveal 4-5-fold lower rates of mutation in the plastid and nucleus than the mitochondrion, which is similar to the mutational pattern observed in red algae and haptophytes, but opposite to that of seed plants. These data, together with data from previous reports, suggest that for much of the known photosynthetic eukaryotic diversity, plastid DNA mutations occur less frequently than those in mitochondrial DNA.
[Mh] Termos MeSH primário: Cyanophora/classificação
DNA Mitocondrial/genética
Taxa de Mutação
Plastídeos/genética
[Mh] Termos MeSH secundário: Evolução Biológica
Núcleo Celular/genética
Cyanophora/genética
DNA de Plantas/genética
Funções Verossimilhança
Filogenia
Análise de Sequência de DNA
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (DNA, Mitochondrial); 0 (DNA, Plant)
[Em] Mês de entrada:1412
[Cu] Atualização por classe:141004
[Lr] Data última revisão:
141004
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:140715
[St] Status:MEDLINE


  9 / 54 MEDLINE  
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[PMID]:24680917
[Au] Autor:Chong J; Jackson C; Kim JI; Yoon HS; Reyes-Prieto A
[Ad] Endereço:Department of Biology, University of New Brunswick, 10 Bailey Drive, Fredericton, New Brunswick E3B 5A3, Canada; Integrated Microbiology Program, Canadian Institute for Advanced Research, Canada.
[Ti] Título:Molecular markers from different genomic compartments reveal cryptic diversity within glaucophyte species.
[So] Source:Mol Phylogenet Evol;76:181-8, 2014 Jul.
[Is] ISSN:1095-9513
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Glaucophytes are the least studied of the three major Archaeplastida (Plantae sensu lato) lineages. It has been largely recognized that comprehensive investigations of glaucophyte genetic and species diversity will shed light on the early evolution of photosynthetic eukaryotes. Here we used molecular phylogenetics and genetic distance estimations of diverse molecular markers to explore strain and species diversity within the glaucophyte genera Cyanophora and Glaucocystis. Single gene and concatenated maximum likelihood analyses of markers from three different genetic compartments consistently recovered similar intrageneric genetic groups. Distance analyses of plastid (psbA and rbcL) and mitochondrial (cob and cox1) genes, and the nuclear internal transcribed spacer (ITS) region, revealed substantial genetic divergence between some Cyanophora paradoxa and Glaucocystis nostochinearum strains. The genetic distances estimated between some glaucophyte strains currently considered the same species are similar or greater than divergence values calculated between different species in other unicellular algae, such as certain green algae and diatoms. The analyzed molecular markers are prospective candidates for future studies of species diversity in glaucophytes. Overall, our results unveil previously unrecognized cryptic diversity within Cyanophora and Glaucocystis species.
[Mh] Termos MeSH primário: Cyanophora/genética
Variação Genética/genética
Genoma/genética
Glaucófitas/genética
Filogenia
[Mh] Termos MeSH secundário: Núcleo Celular/genética
Clorófitas/genética
Cyanophora/citologia
Código de Barras de DNA Taxonômico
Diatomáceas/genética
Marcadores Genéticos/genética
Genômica
Glaucófitas/citologia
Coreia (Geográfico)
Mitocôndrias/genética
América do Norte
Plastídeos/genética
Análise de Sequência de DNA
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Genetic Markers)
[Em] Mês de entrada:1501
[Cu] Atualização por classe:140526
[Lr] Data última revisão:
140526
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:140401
[St] Status:MEDLINE


  10 / 54 MEDLINE  
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[PMID]:24189278
[Au] Autor:Baudelet PH; Gagez AL; Bérard JB; Juin C; Bridiau N; Kaas R; Thiéry V; Cadoret JP; Picot L
[Ad] Endereço:University of La Rochelle, UMRi CNRS 7266 LIENSs, F-17042, La Rochelle, France. lpicot@univ-lr.fr.
[Ti] Título:Antiproliferative activity of Cyanophora paradoxa pigments in melanoma, breast and lung cancer cells.
[So] Source:Mar Drugs;11(11):4390-406, 2013 Nov 01.
[Is] ISSN:1660-3397
[Cp] País de publicação:Switzerland
[La] Idioma:eng
[Ab] Resumo:The glaucophyte Cyanophora paradoxa (Cp) was chemically investigated to identify pigments efficiently inhibiting malignant melanoma, mammary carcinoma and lung adenocarcinoma cells growth. Cp water and ethanol extracts significantly inhibited the growth of the three cancer cell lines in vitro, at 100 µg · mL(-1). Flash chromatography of the Cp ethanol extract, devoid of c-phycocyanin and allophycocyanin, enabled the collection of eight fractions, four of which strongly inhibited cancer cells growth at 100 µg · mL(-1). Particularly, two fractions inhibited more than 90% of the melanoma cells growth, one inducing apoptosis in the three cancer cells lines. The detailed analysis of Cp pigment composition resulted in the discrimination of 17 molecules, ten of which were unequivocally identified by high resolution mass spectrometry. Pheophorbide a, ß-cryptoxanthin and zeaxanthin were the three main pigments or derivatives responsible for the strong cytotoxicity of Cp fractions in cancer cells. These data point to Cyanophora paradoxa as a new microalgal source to purify potent anticancer pigments, and demonstrate for the first time the strong antiproliferative activity of zeaxanthin and ß-cryptoxanthin in melanoma cells.
[Mh] Termos MeSH primário: Neoplasias da Mama/tratamento farmacológico
Proliferação Celular/efeitos dos fármacos
Cyanophora/química
Neoplasias Pulmonares/tratamento farmacológico
Melanoma/tratamento farmacológico
Pigmentos Biológicos/farmacologia
[Mh] Termos MeSH secundário: Antineoplásicos/química
Antineoplásicos/farmacologia
Apoptose/efeitos dos fármacos
Linhagem Celular Tumoral
Criptoxantinas
Cyanophora/metabolismo
Feminino
Seres Humanos
Células MCF-7
Pigmentos Biológicos/química
Neoplasias Cutâneas
Xantofilas/química
Xantofilas/farmacologia
Zeaxantinas
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Antineoplastic Agents); 0 (Cryptoxanthins); 0 (Pigments, Biological); 0 (Xanthophylls); 0 (Zeaxanthins)
[Em] Mês de entrada:1406
[Cu] Atualização por classe:171116
[Lr] Data última revisão:
171116
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:131106
[St] Status:MEDLINE
[do] DOI:10.3390/md11114390



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