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[PMID]:29458477
[Au] Autor:Kwon YM; Kim KW; Kim JYH; Choi TY; Yang SH; Oh CH; Kwon KK; Kim SJ
[Ad] Endereço:1​Department of Applied Research, National Marine Biodiversity Institute of Korea, 75, Jangsan-ro 101beon-gil, Seocheon-gun, Chungcheongnam-do, 33662, Republic of Korea.
[Ti] Título:Euzebyella algicola sp. nov., a marine bacterium of the family Flavobacteriaceae, isolated from green algae.
[So] Source:Int J Syst Evol Microbiol;68(3):764-768, 2018 Mar.
[Is] ISSN:1466-5034
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:A Gram-negative, yellow-pigmented, non-flagellated, gliding, rod-shaped and aerobic bacterium, designated MEBiC 12267 , was isolated from green algae of Jeju Island. 16S rRNA gene sequence analysis revealed that the strain MEBiC 12267 was affiliated to the genus Euzebyella of the family Flavobacteriaceae and showed the highest similarity to Euzebyella marina KCTC 42440 (98.5 %). The DNA-DNA relatedness value of strain MEBiC 12267 with E. marina KCTC 42440 was 25 %. Growth was observed at 10-37 °C (optimum, 30-33 °C), at pH 6.0-9.5 (optimum, 8.0-8.5) and with 0.5-9.0 % (w/v) NaCl (optimum, 2.5-3.5 %). The predominant cellular fatty acids were iso-C15 : 0, iso-C15 : 1 G and iso-C17 : 0 3-OH. The major respiratory quinone was MK-6. Polar lipids included phosphatidylethanolamine, seven unidentified lipids and two unidentified aminolipids. The DNA G+C content was 40.7 mol%. On the basis of the data from the polyphasic taxonomic study, it was concluded that the strain MEBiC 12267 represents a novel species within the genus Euzebyella, for which the name Euzebyella algicola sp. nov. is proposed. The type strain of E. algicola is MEBiC 12267 (=KCCM 43264 =JCM 32170 ).
[Mh] Termos MeSH primário: Clorófitas/microbiologia
Flavobacteriaceae/classificação
Filogenia
[Mh] Termos MeSH secundário: Técnicas de Tipagem Bacteriana
Composição de Bases
DNA Bacteriano/genética
Ácidos Graxos/química
Flavobacteriaceae/genética
Flavobacteriaceae/isolamento & purificação
Hibridização de Ácido Nucleico
Fosfatidiletanolaminas/química
Pigmentação
RNA Ribossômico 16S/genética
República da Coreia
Análise de Sequência de DNA
Vitamina K 2/análogos & derivados
Vitamina K 2/química
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (DNA, Bacterial); 0 (Fatty Acids); 0 (Phosphatidylethanolamines); 0 (RNA, Ribosomal, 16S); 11032-49-8 (Vitamin K 2); 39382-08-6 (phosphatidylethanolamine); 71ANL51TLA (menaquinone 6)
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180308
[Lr] Data última revisão:
180308
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180221
[St] Status:MEDLINE
[do] DOI:10.1099/ijsem.0.002581


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[PMID]:29268103
[Au] Autor:Carusso S; Juárez AB; Moretton J; Magdaleno A
[Ad] Endereço:Universidad de Buenos Aires, Facultad de Farmacia y Bioquímica, Cátedra de Salud Pública e Higiene Ambiental, Junin 956, 4° Piso, C1113 AAC, Buenos Aires, Argentina; Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales, Departamento de Biodiversidad y Biología Experimental y Departa
[Ti] Título:Effects of three veterinary antibiotics and their binary mixtures on two green alga species.
[So] Source:Chemosphere;194:821-827, 2018 Mar.
[Is] ISSN:1879-1298
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:The individual and combined toxicities of chlortetracycline (CTC), oxytetracycline (OTC) and enrofloxacin (ENF) have been examined in two green algae representative of the freshwater environment, the international standard strain Pseudokichneriella subcapitata and the native strain Ankistrodesmus fusiformis. The toxicities of the three antibiotics and their mixtures were similar in both strains, although low concentrations of ENF and CTC + ENF were more toxic in A. fusiformis than in the standard strain. The toxicological interactions of binary mixtures were predicted using the two classical models of additivity: Concentration Addition (CA) and Independent Action (IA), and compared to the experimentally determined toxicities over a range of concentrations between 0.1 and 10 mg L . The CA model predicted the inhibition of algal growth in the three mixtures in P. subcapitata, and in the CTC + OTC and CTC + ENF mixtures in A. fusiformis. However, this model underestimated the experimental results obtained in the OTC + ENF mixture in A. fusiformis. The IA model did not predict the experimental toxicological effects of the three mixtures in either strain. The sum of the toxic units (TU) for the mixtures was calculated. According to these values, the binary mixtures CTC + ENF and OTC + ENF showed an additive effect, and the CTC + OTC mixture showed antagonism in P. subcapitata, whereas the three mixtures showed synergistic effects in A. fusiformis. Although A. fusiformis was isolated from a polluted river, it showed a similar sensitivity with respect to P. subcapitata when it was exposed to binary mixtures of antibiotics.
[Mh] Termos MeSH primário: Antibacterianos/farmacologia
Clorófitas/efeitos dos fármacos
Drogas Veterinárias/farmacologia
[Mh] Termos MeSH secundário: Antibacterianos/toxicidade
Clortetraciclina/toxicidade
Interações Medicamentosas
Fluoroquinolonas/toxicidade
Biologia de Ecossistemas de Água Doce
Oxitetraciclina/toxicidade
Drogas Veterinárias/toxicidade
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Anti-Bacterial Agents); 0 (Fluoroquinolones); 0 (Veterinary Drugs); 3DX3XEK1BN (enrofloxacin); WCK1KIQ23Q (Chlortetracycline); X20I9EN955 (Oxytetracycline)
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180228
[Lr] Data última revisão:
180228
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171222
[St] Status:MEDLINE


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[PMID]:29028601
[Au] Autor:Bakire S; Yang X; Ma G; Wei X; Yu H; Chen J; Lin H
[Ad] Endereço:College of Geography and Environmental Sciences, Zhejiang Normal University, Yingbin Avenue 688, 321004, Jinhua, PR China.
[Ti] Título:Developing predictive models for toxicity of organic chemicals to green algae based on mode of action.
[So] Source:Chemosphere;190:463-470, 2018 Jan.
[Is] ISSN:1879-1298
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Organic chemicals in the aquatic ecosystem may inhibit algae growth and subsequently lead to the decline of primary productivity. Growth inhibition tests are required for ecotoxicological assessments for regulatory purposes. In silico study is playing an important role in replacing or reducing animal tests and decreasing experimental expense due to its efficiency. In this work, a series of theoretical models was developed for predicting algal growth inhibition (log EC ) after 72 h exposure to diverse chemicals. In total 348 organic compounds were classified into five modes of toxic action using the Verhaar Scheme. Each model was established by using molecular descriptors that characterize electronic and structural properties. The external validation and leave-one-out cross validation proved the statistical robustness of the derived models. Thus they can be used to predict log EC values of chemicals that lack authorized algal growth inhibition values (72 h). This work systematically studied algal growth inhibition according to toxic modes and the developed model suite covers all five toxic modes. The outcome of this research will promote toxic mechanism analysis and be made applicable to structural diversity.
[Mh] Termos MeSH primário: Clorófitas/efeitos dos fármacos
Modelos Teóricos
Compostos Orgânicos/toxicidade
Relação Quantitativa Estrutura-Atividade
[Mh] Termos MeSH secundário: Animais
Clorófitas/crescimento & desenvolvimento
Simulação por Computador
Ecossistema
Estrutura Molecular
Compostos Orgânicos/química
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Organic Chemicals)
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180228
[Lr] Data última revisão:
180228
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171014
[St] Status:MEDLINE


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[PMID]:29360855
[Au] Autor:Carrillo JB; Gomez-Casati DF; Martín M; Busi MV
[Ad] Endereço:Centro de Estudios Fotosintéticos y Bioquímicos (CEFOBI-CONICET), Universidad Nacional de Rosario, Rosario, Santa Fe, Argentina.
[Ti] Título:Identification and analysis of OsttaDSP, a phosphoglucan phosphatase from Ostreococcus tauri.
[So] Source:PLoS One;13(1):e0191621, 2018.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Ostreococcus tauri, the smallest free-living (non-symbiotic) eukaryote yet described, is a unicellular green alga of the Prasinophyceae family. It has a very simple cellular organization and presents a unique starch granule and chloroplast. However, its starch metabolism exhibits a complexity comparable to higher plants, with multiple enzyme forms for each metabolic reaction. Glucan phosphatases, a family of enzymes functionally conserved in animals and plants, are essential for normal starch or glycogen degradation in plants and mammals, respectively. Despite the importance of O. tauri microalgae in evolution, there is no information available concerning the enzymes involved in reversible phosphorylation of starch. Here, we report the molecular cloning and heterologous expression of the gene coding for a dual specific phosphatase from O. tauri (OsttaDSP), homologous to Arabidopsis thaliana LSF2. The recombinant enzyme was purified to electrophoretic homogeneity to characterize its oligomeric and kinetic properties accurately. OsttaDSP is a homodimer of 54.5 kDa that binds and dephosphorylates amylopectin. Also, we also determined that residue C162 is involved in catalysis and possibly also in structural stability of the enzyme. Our results could contribute to better understand the role of glucan phosphatases in the metabolism of starch in green algae.
[Mh] Termos MeSH primário: Clorófitas/enzimologia
Glucanos/metabolismo
Monoéster Fosfórico Hidrolases/metabolismo
[Mh] Termos MeSH secundário: Sequência de Aminoácidos
Clonagem Molecular
Dimerização
Cinética
Monoéster Fosfórico Hidrolases/química
Monoéster Fosfórico Hidrolases/genética
Fosforilação
Conformação Proteica
Proteínas Recombinantes/química
Proteínas Recombinantes/genética
Proteínas Recombinantes/metabolismo
Homologia de Sequência de Aminoácidos
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Glucans); 0 (Recombinant Proteins); EC 3.1.3.2 (Phosphoric Monoester Hydrolases)
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180226
[Lr] Data última revisão:
180226
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180124
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0191621


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[PMID]:29406093
[Au] Autor:Ge F; Xiao Y; Yang Y; Wang W; Moe B; Li XF
[Ad] Endereço:College of Environment and Resources, Xiangtan University, Xiangtan, Hunan 411105, China. Electronic address: gefei@xtu.edu.cn.
[Ti] Título:Formation of water disinfection byproduct 2,6-dichloro-1,4-benzoquinone from chlorination of green algae.
[So] Source:J Environ Sci (China);63:1-8, 2018 Jan.
[Is] ISSN:1001-0742
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:We report that green algae in lakes and rivers can serve as precursors of halobenzoquinone (HBQ) disinfection byproducts (DBPs) produced during chlorination. Chlorination of a common green alga, Chlorella vulgaris, produced 2,6-dichloro-1,4-benzoquinone (2,6-DCBQ), the most prevalent HBQ DBP in disinfected water. Under varying pH conditions (pH6.0-9.0), 2,6-DCBQ formation ranged from 0.3 to 2.1µg/mg C with maximum formation at pH8.0. To evaluate the contribution of organic components of C. vulgaris to 2,6-DCBQ formation, we separated the organics into two fractions, the protein-rich fraction of intracellular organic matter (IOM) and the polysaccharide-laden fraction of extracellular organic matter (EOM). Chlorination of IOM and EOM produced 1.4µg/mg C and 0.7µg/mg C of 2,6-DCBQ, respectively. The IOM generated a two-fold higher 2,6-DCBQ formation potential than the EOM fraction, suggesting that proteins are potent 2,6-DCBQ precursors. This was confirmed by the chlorination of proteins extracted from C. vulgaris: the amount of 2,6-DCBQ produced is linearly correlated with the concentration of total algal protein (R =0.98). These results support that proteins are the primary precursors of 2,6-DCBQ in algae, and control of green algal bloom outbreaks in source waters is important for management of HBQ DBPs.
[Mh] Termos MeSH primário: Benzoquinonas/metabolismo
Chlorella vulgaris/fisiologia
Desinfetantes/metabolismo
Poluentes Químicos da Água/metabolismo
[Mh] Termos MeSH secundário: Benzoquinonas/análise
Clorófitas
Desinfetantes/análise
Desinfecção
Halogenação
Poluentes Químicos da Água/análise
Purificação da Água/métodos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Benzoquinones); 0 (Disinfectants); 0 (Water Pollutants, Chemical)
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180216
[Lr] Data última revisão:
180216
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180207
[St] Status:MEDLINE


  6 / 6473 MEDLINE  
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[PMID]:29121566
[Au] Autor:Tian D; Mao H; Lv H; Zheng Y; Peng C; Hou S
[Ad] Endereço:College of Chemical and Environmental Engineering, Anyang Institute of Technology, Anyang 455000, Henan, PR China; Department of Laboratory Medicine and Pathology, University of Alberta, Edmonton T6G 2G3, Alberta, Canada. Electronic address: astdy@126.com.
[Ti] Título:Novel two-tiered approach of ecological risk assessment for pesticide mixtures based on joint effects.
[So] Source:Chemosphere;192:362-371, 2018 Feb.
[Is] ISSN:1879-1298
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Ecological risk assessments for mixtures have attracted considerable attention. In this study, 38 pesticides in the real environment were taken as objects and their toxicities to different organisms from three trophic levels were employed to assess the ecological risk of the mixture. The first tier assessment was based on the CA effect and the obtained sum of risk quotients (SRQ ) were 3.06-9.22. The second tier assessment was based on non-CA effects and the calculated SRQ are 5.37-9.29 using joint effects (TU ) as modified coefficients, which is higher than SRQ and indicates that ignoring joint effects might run the risk of underestimating the actual impact of pesticide mixtures. Due to the influences of synergistic and antagonistic effects, risk contribution of components to mixture risks based on non-CA effects are different from those based on the CA effect. Moreover, it was found that the top 8 dominating components explained 95.5%-99.8% of mixture risks in this study. The dominating components are similar in the two tiers for a given species. Accordingly, a novel two-tiered approach was proposed to assess the ecological risks of mixtures based on joint effects. This study provides new insights for ecological risk assessments with the consideration of joint effects of components in the pesticide mixtures.
[Mh] Termos MeSH primário: Ecologia/métodos
Poluentes Ambientais/farmacologia
Praguicidas/farmacologia
Medição de Risco
[Mh] Termos MeSH secundário: Animais
Clorófitas/efeitos dos fármacos
Combinação de Medicamentos
Peixes
Invertebrados/efeitos dos fármacos
Praguicidas/análise
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Drug Combinations); 0 (Environmental Pollutants); 0 (Pesticides)
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180212
[Lr] Data última revisão:
180212
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171110
[St] Status:MEDLINE


  7 / 6473 MEDLINE  
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[PMID]:29300784
[Au] Autor:Esposito V; Andaloro F; Canese S; Bortoluzzi G; Bo M; Di Bella M; Italiano F; Sabatino G; Battaglia P; Consoli P; Giordano P; Spagnoli F; La Cono V; Yakimov MM; Scotti G; Romeo T
[Ad] Endereço:Dipartimento per il monitoraggio e la tutela dell'ambiente e per la conservazione della biodiversità, Istituto Superiore per la Protezione e la Ricerca ambientale (ISPRA), Milazzo, Italy.
[Ti] Título:Exceptional discovery of a shallow-water hydrothermal site in the SW area of Basiluzzo islet (Aeolian archipelago, South Tyrrhenian Sea): An environment to preserve.
[So] Source:PLoS One;13(1):e0190710, 2018.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:The geological, biological and geochemical features of a particular field of hydrothermal vents, discovered in the Panarea Volcanic Complex during a research survey carried out in 2015, are described for the first time. The site, located at 70-80 m depth off the South-western coast of the islet of Basiluzzo, was named Smoking Land for the presence of a large number of wide and high active chimneys and was characterized in terms of dissolved benthic fluxes, associated macrofauna and megafauna communities and preliminary mineralogy and geochemistry of chimney structures. On the whole field, a total of 39 chimneys, different in size and shape, were closely observed and described; 14 of them showed emission of low temperature hydrothermal fluids of marine origin characterized by acidified chemical conditions. The CTD and benthic chamber measurements highlighted that the Smoking Land is able to form a sea water bottom layer characterized by variable acidity and high DIC and trace elements concentrations; these characteristics weaken moving away from the chimney mouths. The SEM-EDS analysis of the collected solid samples revealed a chimney structure principally composed by amorphous and low crystalline Fe-oxyhydroxides of hydrothermal origins. The ROV explorations revealed a wide coverage of red algae (Peyssonnelia spp.) colonized by the green algae Flabiella petiolata and by suspension feeders, mainly sponges, but also bryozoans, and tubicolous polychaetes. Although novent-exclusive species were identified, the benthic communities found in association to the chimneys included more taxa than those observed in the surrounding no-vent rocky areas. These first findings evidence a submarine dynamic habitat where geological, chemical and biological processes are intimately connected, making the Smoking Land an important site in terms of marine heritage that should be safeguarded and protected.
[Mh] Termos MeSH primário: Fontes Hidrotermais
Oceanos e Mares
[Mh] Termos MeSH secundário: Animais
Briozoários
Clorófitas
Conservação dos Recursos Naturais
Concentração de Íons de Hidrogênio
Microscopia Eletrônica de Varredura
Poríferos
Rodófitas
Difração de Raios X
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180201
[Lr] Data última revisão:
180201
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180105
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0190710


  8 / 6473 MEDLINE  
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[PMID]:27779617
[Au] Autor:Lopes Dos Santos A; Gourvil P; Tragin M; Noël MH; Decelle J; Romac S; Vaulot D
[Ad] Endereço:Sorbonne Universités, UPMC Université Paris 06, CNRS, UMR 7144 Station Biologique de Roscoff, Roscoff, France.
[Ti] Título:Diversity and oceanic distribution of prasinophytes clade VII, the dominant group of green algae in oceanic waters.
[So] Source:ISME J;11(2):512-528, 2017 02.
[Is] ISSN:1751-7370
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Prasinophytes clade VII is a group of pico/nano-planktonic green algae (division Chlorophyta) for which numerous ribosomal RNA (rRNA) sequences have been retrieved from the marine environment in the last 15 years. A large number of strains have also been isolated but have not yet received a formal taxonomic description. A phylogenetic analysis of available strains using both the nuclear 18S and plastidial 16S rRNA genes demonstrates that this group composes at least 10 different clades: A1-A7 and B1-B3. Analysis of sequences from the variable V9 region of the 18S rRNA gene collected during the Tara Oceans expedition and in the frame of the Ocean Sampling Day consortium reveal that clade VII is the dominant Chlorophyta group in oceanic waters, replacing Mamiellophyceae, which have this role in coastal waters. At some location, prasinophytes clade VII can even be the dominant photosynthetic eukaryote representing up to 80% of photosynthetic metabarcodes overall. B1 and A4 are the overall dominant clades and different clades seem to occupy distinct niches, for example, A6 is dominant in surface Mediterranean Sea waters, whereas A4 extend to high temperate latitudes. Our work demonstrates that prasinophytes clade VII constitute a highly diversified group, which is a key component of phytoplankton in open oceanic waters but has been neglected in the conceptualization of marine microbial diversity and carbon cycle.
[Mh] Termos MeSH primário: Clorófitas/genética
Eucariotos/genética
Variação Genética
Fitoplâncton/genética
[Mh] Termos MeSH secundário: Clorófitas/classificação
DNA Ribossômico/química
DNA Ribossômico/genética
Eucariotos/classificação
Eucariotos/isolamento & purificação
Mar Mediterrâneo
Oceanos e Mares
Fotossíntese
Filogenia
Fitoplâncton/classificação
Fitoplâncton/isolamento & purificação
Água do Mar
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (DNA, Ribosomal)
[Em] Mês de entrada:1708
[Cu] Atualização por classe:180201
[Lr] Data última revisão:
180201
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161026
[St] Status:MEDLINE
[do] DOI:10.1038/ismej.2016.120


  9 / 6473 MEDLINE  
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[PMID]:29244187
[Au] Autor:Salinas-Giegé T; Cavaiuolo M; Cognat V; Ubrig E; Remacle C; Duchêne AM; Vallon O; Maréchal-Drouard L
[Ad] Endereço:Institut de biologie moléculaire des plantes, CNRS, Université de Strasbourg, 67084 Strasbourg, France.
[Ti] Título:Polycytidylation of mitochondrial mRNAs in Chlamydomonas reinhardtii.
[So] Source:Nucleic Acids Res;45(22):12963-12973, 2017 Dec 15.
[Is] ISSN:1362-4962
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:The unicellular photosynthetic organism, Chlamydomonas reinhardtii, represents a powerful model to study mitochondrial gene expression. Here, we show that the 5'- and 3'-extremities of the eight Chlamydomonas mitochondrial mRNAs present two unusual characteristics. First, all mRNAs start primarily at the AUG initiation codon of the coding sequence which is often marked by a cluster of small RNAs. Second, unusual tails are added post-transcriptionally at the 3'-extremity of all mRNAs. The nucleotide composition of the tails is distinct from that described in any other systems and can be partitioned between A/U-rich tails, predominantly composed of Adenosine and Uridine, and C-rich tails composed mostly of Cytidine. Based on 3' RACE experiments, 22% of mRNAs present C-rich tails, some of them composed of up to 20 consecutive Cs. Polycytidylation is specific to mitochondria and occurs primarily on mRNAs. This unprecedented post-transcriptional modification seems to be a specific feature of the Chlorophyceae class of green algae and points out the existence of novel strategies in mitochondrial gene expression.
[Mh] Termos MeSH primário: Chlamydomonas reinhardtii/genética
Mitocôndrias/genética
RNA Mensageiro/genética
Transcrição Genética
[Mh] Termos MeSH secundário: Sequência de Bases
Chlamydomonas reinhardtii/metabolismo
Clorófitas/classificação
Clorófitas/genética
Genoma Mitocondrial/genética
Mitocôndrias/metabolismo
Filogenia
Poli C/metabolismo
RNA Mensageiro/metabolismo
Homologia de Sequência do Ácido Nucleico
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (RNA, Messenger); 0 (mitochondrial messenger RNA); 30811-80-4 (Poly C)
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180115
[Lr] Data última revisão:
180115
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171216
[St] Status:MEDLINE
[do] DOI:10.1093/nar/gkx903


  10 / 6473 MEDLINE  
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[PMID]:28745761
[Au] Autor:Wang Y; Deng W; Wang F; Su Y; Feng Y; Chen P; Ma J; Su H; Yao K; Liu Y; Lv W; Liu G
[Ad] Endereço:School of Environmental Science and Engineering, Guangdong University of Technology, No. 100 Waihuan Xi Road, Guangzhou Higher Education Mega Center, Panyu District, Guangzhou 510006, China. liugg615@163.com.
[Ti] Título:Study of the simulated sunlight photolysis mechanism of ketoprofen: the role of superoxide anion radicals, transformation byproducts, and ecotoxicity assessment.
[So] Source:Environ Sci Process Impacts;19(9):1176-1184, 2017 Sep 20.
[Is] ISSN:2050-7895
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:The aim of this study was to investigate the photolysis mechanism of ketoprofen (KET) under simulated sunlight. The results demonstrated that the photolysis of KET aligned well with pseudo first-order kinetics. Radical scavenging experiments and dissolved oxygen experiments revealed that the superoxide anion radical (O Ë™ ) played a primary role in the photolytic process in pure water. Bicarbonate slightly increased the photodegradation of KET through generating carbonate radicals, while DOM inhibited the photolysis via both attenuating light and competing radicals. Moreover, Zhujiang river water inhibited KET phototransformation. Potential KET degradation pathways were proposed based on the identification of products using LC/MS/MS and GC/MS techniques. The theoretical prediction of reaction sites was derived from Frontier Electron Densities (FEDs), which primarily involved the KET decarboxylation reaction. The ecotoxicity of the treated solutions was evaluated by employing Daphnia magna and V. fischeri as biological indicators. Ecotoxicity was also hypothetically predicted through the "ecological structure-activity relationship" (ECOSAR) program, which revealed that toxic products might be generated during the photolysis process.
[Mh] Termos MeSH primário: Cetoprofeno/toxicidade
Modelos Teóricos
Fotólise
Luz Solar
Superóxidos/toxicidade
Poluentes Químicos da Água/toxicidade
[Mh] Termos MeSH secundário: Aliivibrio fischeri/efeitos dos fármacos
Animais
Clorófitas/efeitos dos fármacos
Daphnia/efeitos dos fármacos
Peixes/crescimento & desenvolvimento
Cetoprofeno/análise
Cetoprofeno/efeitos da radiação
Cinética
Valor Preditivo dos Testes
Superóxidos/análise
Espectrometria de Massas em Tandem
Testes de Toxicidade Aguda
Testes de Toxicidade Crônica
Poluentes Químicos da Água/análise
Poluentes Químicos da Água/efeitos da radiação
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Water Pollutants, Chemical); 11062-77-4 (Superoxides); 90Y4QC304K (Ketoprofen)
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180108
[Lr] Data última revisão:
180108
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170727
[St] Status:MEDLINE
[do] DOI:10.1039/c7em00111h



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