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[PMID]:28965024
[Au] Autor:Ohashi S; Kuroda K; Takano T; Suzuki Y; Fujiwara T; Abe H; Kagawa A; Sugiyama M; Kubojima Y; Zhang C; Yamamoto K
[Ad] Endereço:Department of Wood Properties and Processing, Forestry and Forest Products Research Institute (FFPRI), 1 Matsunosato, Tsukuba, Ibaraki 305-8687, Japan; Center for Forest Restoration and Radioecology, FFPRI, 1 Matsunosato, Tsukuba, Ibaraki 305-8687, Japan. Electronic address: shinta.res@gmail.com.
[Ti] Título:Temporal trends in Cs concentrations in the bark, sapwood, heartwood, and whole wood of four tree species in Japanese forests from 2011 to 2016.
[So] Source:J Environ Radioact;178-179:335-342, 2017 Nov.
[Is] ISSN:1879-1700
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:To understand the changes in radiocesium ( Cs) concentrations in stem woods after the Fukushima Dai-ichi Nuclear Power Plant (FDNPP) accident, we investigated Cs concentrations in the bark, sapwood, heartwood, and whole wood of four major tree species at multiple sites with different levels of radiocesium deposition from the FDNPP accident since 2011 (since 2012 at some sites): Japanese cedar at four sites, hinoki cypress and Japanese konara oak at two sites, and Japanese red pine at one site. Our previous report on Cs concentrations in bark and whole wood samples collected from 2011 to 2015 suggested that temporal variations were different among sites even within the same species. In the present study, we provided data on bark and whole wood samples in 2016 and separately measured Cs concentrations in sapwood and heartwood samples from 2011 to 2016; we further discussed temporal trends in Cs concentrations in each part of tree stems, particularly those in Cs distributions between sapwood and heartwood, in relation to their species and site dependencies. Temporal trends in bark and whole wood samples collected from 2011 to 2016 were consistent with those reported in samples collected from 2011 to 2015. Temporal variations in Cs concentrations in barks showed either a decreasing trend or no clear trend, implying that Cs deposition in barks is inhomogeneous and that decontamination is relatively slow in some cases. Temporal trends in Cs concentrations in sapwood, heartwood, and whole wood were different among species and also among sites within the same species. Relatively common trends within the same species, which were increasing, were observed in cedar heartwood, and in oak sapwood and whole wood. On the other hand, the ratio of Cs concentration in heartwood to that in sapwood (fresh weight basis) was commonly increased to more than 2 in cedar, although distinct temporal trends were not found in the other species, for which the ratio was around 1 in cypress and pine and below 0.5 in oak, suggesting that Cs transfer from sapwood to heartwood shows species dependency. Consequently, the species dependency of Cs transfer within the tree appears easily, while that from the environment to the trees can be masked by various factors. Thus, prediction of Cs concentrations in stem wood should be carried out carefully as it still requires investigations at multiple sites with a larger sample size and an understanding of the species-specific Cs transfer mechanism.
[Mh] Termos MeSH primário: Radioisótopos de Césio/análise
Acidente Nuclear de Fukushima
Monitoramento de Radiação
Poluentes Radioativos/análise
Árvores/química
[Mh] Termos MeSH secundário: Chamaecyparis
Cryptomeria
Florestas
Madeira/química
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Cesium Radioisotopes); 0 (Radioactive Pollutants)
[Em] Mês de entrada:1711
[Cu] Atualização por classe:171110
[Lr] Data última revisão:
171110
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171002
[St] Status:MEDLINE


  2 / 127 MEDLINE  
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[PMID]:28089043
[Au] Autor:Vettraino A; Brasier CM; Webber JF; Hansen EM; Green S; Robin C; Tomassini A; Bruni N; Vannini A
[Ad] Endereço:DIBAF, University of Tuscia, Via S. Camillo de Lellis, Viterbo, 01100, Italy.
[Ti] Título:Contrasting microsatellite diversity in the evolutionary lineages of Phytophthora lateralis.
[So] Source:Fungal Biol;121(2):112-126, 2017 Feb.
[Is] ISSN:1878-6146
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:Following recent discovery of Phytophthora lateralis on native Chamaecyparis obtusa in Taiwan, four phenotypically distinct lineages were discriminated: the Taiwan J (TWJ) and Taiwan K (TWK) in Taiwan, the Pacific Northwest (PNW) in North America and Europe and the UK in west Scotland. Across the four lineages, we analysed 88 isolates from multiple sites for microsatellite diversity. Twenty-one multilocus genotypes (MLGs) were resolved with high levels of diversity of the TWK and PNW lineages. No alleles were shared between the PNW and the Taiwanese lineages. TWK was heterozygous at three loci, whereas TWJ isolates were homozygous apart from one isolate, which exhibited a unique allele also present in the TWK lineage. PNW lineage was heterozygous at three loci. The evidence suggests its origin may be a yet unknown Asian source. North American and European PNW isolates shared all their alleles and also a dominant MLG, consistent with a previous proposal that this lineage is a recent introduction into Europe from North America. The UK lineage was monomorphic and homozygous at all loci. It shared its alleles with the PNW and the TWJ and TWK lineages, hence a possible origin in a recent hybridisation event between a Taiwan lineage and PNW cannot be ruled out.
[Mh] Termos MeSH primário: Variação Genética
Repetições de Microssatélites
Phytophthora/classificação
Phytophthora/genética
[Mh] Termos MeSH secundário: Chamaecyparis/microbiologia
Europa (Continente)
Evolução Molecular
América do Norte
Phytophthora/isolamento & purificação
Análise de Sequência de DNA
Taiwan
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170926
[Lr] Data última revisão:
170926
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170117
[St] Status:MEDLINE


  3 / 127 MEDLINE  
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[PMID]:27319153
[Au] Autor:Bae MS; Park DH; Choi CY; Kim GY; Yoo JC; Cho SS
[Ti] Título:Essential Oils and Non-volatile Compounds Derived from Chamaecyparis obtusa: Broad Spectrum Antimicrobial Activity against Infectious Bacteria and MDR(multidrug resistant) Strains.
[So] Source:Nat Prod Commun;11(5):693-4, 2016 May.
[Is] ISSN:1934-578X
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:The aim of this study was to evaluate the antibacterial activity of essential oil from Chamaecyparis obtusa against general infectious microbes and drug resistant strains of clinical origin. The results indicate that both essential oil and non-volatile residue have broad inhibitory activity against test strains. Essential oil and non-volatile residues showed antimicrobial activity not only against general infectious bacteria, but also against methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant enterococci (VRE) strains.
[Mh] Termos MeSH primário: Anti-Infecciosos/análise
Chamaecyparis/química
Óleos Voláteis/química
[Mh] Termos MeSH secundário: Farmacorresistência Bacteriana Múltipla
Testes de Sensibilidade Microbiana
Óleos Voláteis/análise
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Anti-Infective Agents); 0 (Oils, Volatile)
[Em] Mês de entrada:1608
[Cu] Atualização por classe:160620
[Lr] Data última revisão:
160620
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160621
[St] Status:MEDLINE


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[PMID]:26936418
[Au] Autor:Park Y; Yoo SA; Kim WU; Cho CS; Woo JM; Yoon CH
[Ad] Endereço:Catholic Research Institutes of Medical Science, Catholic University of Korea, Seoul 137­701, Republic of Korea.
[Ti] Título:Anti-inflammatory effects of essential oils extracted from Chamaecyparis obtusa on murine models of inflammation and RAW 264.7 cells.
[So] Source:Mol Med Rep;13(4):3335-41, 2016 Apr.
[Is] ISSN:1791-3004
[Cp] País de publicação:Greece
[La] Idioma:eng
[Ab] Resumo:Antimicrobial, antifungal and anti-inflammatory effects of essential oils extracted from Chamaecyparis obtusa (EOCO) have previously been reported. In the present study, the anti-inflammatory effects of EOCO were investigated in two murine models of inflammation: Carrageenan-induced paw edema and thioglycollate-induced peritonitis, and in lipopolysaccharide (LPS)-stimulated RAW 264.7 macrophage cells. The expression levels of proinflammatory cytokines were analyzed by ELISA, the expression of nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2) were determined by western blotting, and nitrite concentration was measured using Griess reagent. In mice with carrageenan-induced edema, paw thickness and the expression levels of interleukin (IL)­1ß and IL-6 in paw homogenates were significantly decreased in the EOCO (5 and 10 mg/kg) group, as compared with the control group. In mice with thioglycollate-induced peritonitis, treatment with EOCO (5 and 10 mg/kg) reduced the number of total cells and suppressed tumor necrosis factor­α (TNF­α), IL­1ß and IL­6 levels in peritoneal fluid. In addition, EOCO reduced nitric oxide, TNF­α and IL­6 production, and suppressed iNOS and COX­2 expression in LPS­stimulated RAW 264.7 cells. These results suggest that EOCO may exert anti­inflammatory effects in vivo and in vitro, and that these effects may be associated with the inhibition of inflammatory mediators. Therefore, EOCO may be considered an effective therapeutic agent for the treatment of inflammatory diseases.
[Mh] Termos MeSH primário: Anti-Inflamatórios/uso terapêutico
Chamaecyparis/química
Edema/tratamento farmacológico
Óleos Voláteis/uso terapêutico
Peritonite/tratamento farmacológico
[Mh] Termos MeSH secundário: Animais
Anti-Inflamatórios/química
Anti-Inflamatórios/farmacologia
Carragenina/toxicidade
Sobrevivência Celular/efeitos dos fármacos
Chamaecyparis/metabolismo
Ciclo-Oxigenase 2/metabolismo
Citocinas/análise
Modelos Animais de Doenças
Edema/induzido quimicamente
Edema/patologia
Lipopolissacarídeos/toxicidade
Macrófagos/citologia
Macrófagos/efeitos dos fármacos
Macrófagos/metabolismo
Masculino
Camundongos
Camundongos Endogâmicos C57BL
Óxido Nítrico/análise
Óxido Nítrico Sintase Tipo II/metabolismo
Óleos Voláteis/química
Óleos Voláteis/farmacologia
Peritonite/induzido quimicamente
Peritonite/patologia
Células RAW 264.7
Tioglicolatos/toxicidade
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Anti-Inflammatory Agents); 0 (Cytokines); 0 (Lipopolysaccharides); 0 (Oils, Volatile); 0 (Thioglycolates); 31C4KY9ESH (Nitric Oxide); 9000-07-1 (Carrageenan); EC 1.14.13.39 (Nitric Oxide Synthase Type II); EC 1.14.99.1 (Cyclooxygenase 2)
[Em] Mês de entrada:1612
[Cu] Atualização por classe:161230
[Lr] Data última revisão:
161230
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160304
[St] Status:MEDLINE
[do] DOI:10.3892/mmr.2016.4905


  5 / 127 MEDLINE  
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[PMID]:26818592
[Au] Autor:Nakaba S; Hirai A; Kudo K; Yamagishi Y; Yamane K; Kuroda K; Nugroho WD; Kitin P; Funada R
[Ad] Endereço:Faculty of Agriculture, Tokyo University of Agriculture and Technology, 3-5-8 Saiwai-cho, Fuchu, Tokyo 183-8509, Japan.
[Ti] Título:Cavitation of intercellular spaces is critical to establishment of hydraulic properties of compression wood of Chamaecyparis obtusa seedlings.
[So] Source:Ann Bot;117(3):457-63, 2016 Mar.
[Is] ISSN:1095-8290
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:BACKGROUND AND AIMS: When the orientation of the stems of conifers departs from the vertical as a result of environmental influences, conifers form compression wood that results in restoration of verticality. It is well known that intercellular spaces are formed between tracheids in compression wood, but the function of these spaces remains to be clarified. In the present study, we evaluated the impact of these spaces in artificially induced compression wood in Chamaecyparis obtusa seedlings. METHODS: We monitored the presence or absence of liquid in the intercellular spaces of differentiating xylem by cryo-scanning electron microscopy. In addition, we analysed the relationship between intercellular spaces and the hydraulic properties of the compression wood. KEY RESULTS: Initially, we detected small intercellular spaces with liquid in regions in which the profiles of tracheids were not rounded in transverse surfaces, indicating that the intercellular spaces had originally contained no gases. In the regions where tracheids had formed secondary walls, we found that some intercellular spaces had lost their liquid. Cavitation of intercellular spaces would affect hydraulic conductivity as a consequence of the induction of cavitation in neighbouring tracheids. CONCLUSIONS: Our observations suggest that cavitation of intercellular spaces is the critical event that affects not only the functions of intercellular spaces but also the hydraulic properties of compression wood.
[Mh] Termos MeSH primário: Chamaecyparis/fisiologia
Espaço Extracelular/metabolismo
Plântulas/fisiologia
Água/metabolismo
Madeira/fisiologia
[Mh] Termos MeSH secundário: Microscopia de Fluorescência
Plântulas/ultraestrutura
Madeira/ultraestrutura
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
059QF0KO0R (Water)
[Em] Mês de entrada:1611
[Cu] Atualização por classe:170301
[Lr] Data última revisão:
170301
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160129
[St] Status:MEDLINE
[do] DOI:10.1093/aob/mcv195


  6 / 127 MEDLINE  
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[PMID]:26703452
[Au] Autor:Begum S; Kudo K; Matsuoka Y; Nakaba S; Yamagishi Y; Nabeshima E; Rahman MH; Nugroho WD; Oribe Y; Jin HO; Funada R
[Ad] Endereço:Faculty of Agriculture, Tokyo University of Agriculture and Technology, Fuchu-Tokyo 183-8509, Japan, Faculty of Agriculture, Bangladesh Agricultural University, Mymensingh 2202, Bangladesh.
[Ti] Título:Localized cooling of stems induces latewood formation and cambial dormancy during seasons of active cambium in conifers.
[So] Source:Ann Bot;117(3):465-77, 2016 Mar.
[Is] ISSN:1095-8290
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:BACKGROUND AND AIMS: In temperate regions, trees undergo annual cycles of cambial growth, with periods of cambial activity and dormancy. Environmental factors might regulate the cambial growth, as well as the development of cambial derivatives. We investigated the effects of low temperature by localized cooling on cambial activity and latewood formation in two conifers, Chamaecyparis obtusa and Cryptomeria japonica. METHODS: A plastic rubber tube that contained cooled water was wrapped around a 30-cm-wide portion of the main stem of Chamaecyparis obtusa and Cryptomeria japonica trees during seasons of active cambium. Small blocks were collected from both cooled and non-cooled control portions of the stems for sequential observations of cambial activity and for anatomical measurements of cell morphology by light microscopy and image analysis. KEY RESULTS: The effect of localized cooling was first observed on differentiating tracheids. Tracheids narrow in diameter and with significantly decreased cambial activity were evident 5 weeks after the start of cooling in these stems. Eight weeks after the start of cooling, tracheids with clearly diminished diameters and thickened cell walls were observed in these stems. Thus, localized low temperature induced narrow diameters and obvious thickening of secondary cell walls of tracheids, which were identified as latewood tracheids. Two months after the cessation of cooling, a false annual ring was observed and cambium became active again and produced new tracheids. In Cryptomeria japonica, cambial activity ceased earlier in locally cooled portions of stems than in non-cooled stems, indicating that the cambium had entered dormancy sooner in the cooled stems. CONCLUSIONS: Artificial cooling of stems induced latewood formation and cessation of cambial activity, indicating that cambium and its derivatives can respond directly to changes in temperature. A decrease in the temperature of the stem is a critical factor in the control of cambial activity and xylem differentiation in trees.
[Mh] Termos MeSH primário: Câmbio/fisiologia
Temperatura Baixa
Coniferophyta/fisiologia
Caules de Planta/fisiologia
Estações do Ano
Madeira/fisiologia
[Mh] Termos MeSH secundário: Ar
Chamaecyparis/fisiologia
Cryptomeria/fisiologia
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Em] Mês de entrada:1611
[Cu] Atualização por classe:170301
[Lr] Data última revisão:
170301
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:151226
[St] Status:MEDLINE
[do] DOI:10.1093/aob/mcv181


  7 / 127 MEDLINE  
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[PMID]:26507270
[Au] Autor:Yoshinaga A; Kamitakahara H; Takabe K
[Ad] Endereço:Laboratory of Tree Cell Biology, Division of Forest and Biomaterials Science, Graduate School of Agriculture, Kyoto University, Sakyo-ku, Kyoto 606-8502, Japan aryosshy@kais.kyoto-u.ac.jp.
[Ti] Título:Distribution of coniferin in differentiating normal and compression woods using MALDI mass spectrometric imaging coupled with osmium tetroxide vapor treatment.
[So] Source:Tree Physiol;36(5):643-52, 2016 May.
[Is] ISSN:1758-4469
[Cp] País de publicação:Canada
[La] Idioma:eng
[Ab] Resumo:Matrix-assisted laser desorption/ionization mass spectrometric imaging (MALDI-MSI) was employed to detect monolignol glucosides in differentiating normal and compression woods of two Japanese softwoods, Chamaecyparis obtusa and Cryptomeria japonica Comparison of matrix-assisted laser desorption/ionization time-of-flight mass spectrometry collision-induced dissociation fragmentation analysis and structural time-of-flight (MALDI-TOF CID-FAST) spectra between coniferin and differentiating xylem also confirmed the presence of coniferin in differentiating xylem. However, as matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) and MALDI-TOF CID-FAST spectra of sucrose were similar to those of coniferin, it was difficult to distinguish the distribution of coniferin and sucrose using MALDI-MSI and collision-induced dissociation measurement only. To solve this problem, osmium tetroxide vapor was applied to sections of differentiating xylem. This vapor treatment caused peak shifts corresponding to the introduction of two hydroxyl groups to the C=C double bond in coniferin. The treatment did not cause a peak shift for sucrose, and therefore was effective in distinguishing coniferin and sucrose. Thus, it was found that MALDI-MSI combined with osmium tetroxide vapor treatment is a useful method to detect coniferin in differentiating xylem.
[Mh] Termos MeSH primário: Chamaecyparis/metabolismo
Cinamatos/metabolismo
Cryptomeria/metabolismo
Madeira/metabolismo
[Mh] Termos MeSH secundário: Tetróxido de Ósmio/química
Espectrometria de Massas por Ionização e Dessorção a Laser Assistida por Matriz
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Cinnamates); M6616XLU2J (coniferin); P40W033BGM (Osmium Tetroxide)
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170920
[Lr] Data última revisão:
170920
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:151029
[St] Status:MEDLINE
[do] DOI:10.1093/treephys/tpv116


  8 / 127 MEDLINE  
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[PMID]:26694076
[Au] Autor:Ikei H; Song C; Miyazaki Y
[Ad] Endereço:Center for Environment, Health and Field Sciences, Chiba University, 6-2-1 Kashiwa-no-ha, Kashiwa, Chiba, 277-0882, Japan. ikei0224@ffpri.affrc.go.jp.
[Ti] Título:Physiological effect of olfactory stimulation by Hinoki cypress (Chamaecyparis obtusa) leaf oil.
[So] Source:J Physiol Anthropol;34:44, 2015 Dec 22.
[Is] ISSN:1880-6805
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: In recent years, increasing attention has been paid to the physiological effects of nature-derived stimulation. The physiological relaxation effects caused by forest-derived olfactory stimuli have been demonstrated. However, there are no studies on the physiological effects of olfactory stimuli by Hinoki cypress (Chamaecyparis obtusa) leaves. We investigated the effects of olfactory stimulation by Hinoki cypress leaf oil on the left/right prefrontal cortex activity, assessed using near-infrared time-resolved spectroscopy (TRS), and on the autonomic nervous activity, assessed by measuring heart rate variability (HRV). METHOD: Thirteen female university students (mean age, 21.5 ± 1.0 years) participated in the study. Physiological measurements were performed in an artificial climate maintained at 25 °C, 50% relative humidity, and 230-lx illumination. Hinoki cypress leaf oil was used as an olfactory stimulation with air as the control. The odor was administered for 90 s, while the subjects sat with their eyes closed. Oxyhemoglobin (oxy-Hb) concentrations were measured in the prefrontal cortex using TRS. The high-frequency (HF) component of HRV, which is an estimate of parasympathetic nervous activity, and the low-frequency (LF)/(LF + HF) ratio, which is an estimate of sympathetic nervous activity, were measured by electrocardiography. A modified semantic differential method was used to perform subjective evaluations. RESULTS: Olfactory stimulation by Hinoki cypress leaf oil induced a significant reduction in oxy-Hb concentration in the right prefrontal cortex and increased parasympathetic nervous activity. The subjects reported feeling more comfortable. CONCLUSION: These findings indicate that olfactory stimulation by Hinoki cypress leaf oil induces physiological relaxation.
[Mh] Termos MeSH primário: Aromaterapia
Chamaecyparis/química
Frequência Cardíaca/efeitos dos fármacos
Oxiemoglobinas/análise
Óleos Vegetais/farmacologia
[Mh] Termos MeSH secundário: Administração por Inalação
Adulto
Feminino
Seres Humanos
Folhas de Planta/química
Óleos Vegetais/administração & dosagem
Óleos Vegetais/química
Córtex Pré-Frontal/irrigação sanguínea
Córtex Pré-Frontal/efeitos dos fármacos
Relaxamento
Espectroscopia de Luz Próxima ao Infravermelho
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Oxyhemoglobins); 0 (Plant Oils)
[Em] Mês de entrada:1607
[Cu] Atualização por classe:170220
[Lr] Data última revisão:
170220
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:151224
[St] Status:MEDLINE
[do] DOI:10.1186/s40101-015-0082-2


  9 / 127 MEDLINE  
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[PMID]:26624577
[Au] Autor:Lee SH; Do HS; Min KJ
[Ad] Endereço:Department of Biological Sciences, Inha University, Incheon, Korea.
[Ti] Título:Effects of Essential Oil from Hinoki Cypress, Chamaecyparis obtusa, on Physiology and Behavior of Flies.
[So] Source:PLoS One;10(12):e0143450, 2015.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Phytoncides, which are volatile substances emitted from plants for protection against plant pathogens and insects, are known to have insecticidal, antimicrobial, and antifungal activities. In contrast to their negative effects on microorganisms and insects, phytoncides have been shown to have beneficial effects on human health. Essential oil from Hinoki cypress (Chamaecyparis obtusa) is mostly used in commercial products such as air purifiers. However, the physiological/behavioral impact of essential oil from C. obtusa on insects is not established. In this study, we tested the effects of essential oil extracted from C. obtusa on the physiologies and behaviors of Drosophila melanogaster and Musca domestica. Exposure to essential oil from C. obtusa decreased the lifespan, fecundity, locomotive activity, and developmental success rate of D. melanogaster. In addition, both fruit flies and house flies showed strong repellent behavioral responses to the essential oil, with duration times of about 5 hours at 70 µg/ml. These results suggest that essential oil from C. obtusa can be used as a 'human-friendly' alternative insect repellent.
[Mh] Termos MeSH primário: Comportamento Animal/efeitos dos fármacos
Chamaecyparis/química
Drosophila melanogaster/efeitos dos fármacos
Drosophila melanogaster/fisiologia
Moscas Domésticas/efeitos dos fármacos
Moscas Domésticas/fisiologia
Óleos Voláteis/farmacologia
[Mh] Termos MeSH secundário: Animais
Aprendizagem da Esquiva/efeitos dos fármacos
Feminino
Fertilidade/efeitos dos fármacos
Repelentes de Insetos/farmacologia
Longevidade/efeitos dos fármacos
Masculino
Atividade Motora/efeitos dos fármacos
Análise de Sobrevida
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Insect Repellents); 0 (Oils, Volatile)
[Em] Mês de entrada:1606
[Cu] Atualização por classe:170220
[Lr] Data última revisão:
170220
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:151202
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0143450


  10 / 127 MEDLINE  
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[PMID]:26590113
[Au] Autor:Park Y; Jung SM; Yoo SA; Kim WU; Cho CS; Park BJ; Woo JM; Yoon CH
[Ad] Endereço:Catholic Research Institutes of Medical Sciences, Catholic University of Korea, Seoul 137-701, Republic of Korea.
[Ti] Título:Antinociceptive and anti-inflammatory effects of essential oil extracted from Chamaecyparis obtusa in mice.
[So] Source:Int Immunopharmacol;29(2):320-325, 2015 Dec.
[Is] ISSN:1878-1705
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:Essential oil extracted from Chamaecyparis obtusa (EOCO) consists of several monoterpenes with anti-inflammatory effects. Monoterpenes are expected to have an analgesic effect through inhibition of pro-inflammatory mediators. The present study investigated the anti-nociceptive and anti-inflammatory effects of EOCO in animal models of pain. Intraperitoneal injection with EOCO (5 or 10mg/kg), aspirin (positive control, 300mg/kg), or DMSO (negative control) was performed 1h before the nociception tests: acetic acid-induced writhing response, formalin test, and hot plate test in mice, and acidic saline-induced allodynia in rats. The expression of pro-inflammatory cytokines and pro-inflammatory enzymes in formalin-injected paws was determined by ELISA and western blotting, respectively. Treatment with EOCO significantly reduced acetic acid-induced writhing and paw-licking time in late response of the formalin tests. The anti-nociceptive effect was comparable with aspirin. However, EOCO did not affect the reaction time of licking of the hind paws or jumping in hot plate test and the mechanical withdrawal thresholds in acidic saline-induced allodynia model. Formalin-injected paws of mice treated with EOCO revealed the down-regulated expression of tumor necrosis factor-α, interleukin-1ß, inducible nitric oxide synthase, and cyclooxygenase-2, as compared with those of control mice. These data showed the anti-nociceptive and anti-inflammatory effects of EOCO. The pain-relieving effect might be attributed to inhibition of peripheral pain in association with inflammatory response. EOCO could be a useful therapeutic strategy to manage pain and inflammatory diseases.
[Mh] Termos MeSH primário: Analgésicos/farmacologia
Anti-Inflamatórios/farmacologia
Chamaecyparis/química
Óleos Voláteis/farmacologia
Extratos Vegetais/farmacologia
[Mh] Termos MeSH secundário: Ácido Acético
Animais
Aspirina/farmacologia
Citocinas/biossíntese
Temperatura Alta
Hiperalgesia/induzido quimicamente
Hiperalgesia/prevenção & controle
Injeções Intraperitoneais
Masculino
Camundongos
Camundongos Endogâmicos C57BL
Dor/induzido quimicamente
Dor/prevenção & controle
Medição da Dor/efeitos dos fármacos
Ratos
Ratos Sprague-Dawley
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Analgesics); 0 (Anti-Inflammatory Agents); 0 (Cytokines); 0 (Oils, Volatile); 0 (Plant Extracts); Q40Q9N063P (Acetic Acid); R16CO5Y76E (Aspirin)
[Em] Mês de entrada:1609
[Cu] Atualização por classe:170730
[Lr] Data última revisão:
170730
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:151122
[St] Status:MEDLINE



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