Base de dados : MEDLINE
Pesquisa : B01.650.940.800.575.525 [Categoria DeCS]
Referências encontradas : 61 [refinar]
Mostrando: 1 .. 10   no formato [Detalhado]

página 1 de 7 ir para página                  

  1 / 61 MEDLINE  
              next record last record
seleciona
para imprimir
Fotocópia
[PMID]:28625948
[Au] Autor:García MV; Poser GLV; Apel M; Tlatilpa RC; Mendoza-Ruiz A; Villarreal ML; Henriques AT; Taketa AC
[Ad] Endereço:Centro de Investigación en Biotecnología, Universidad Autónoma del Estado de Morelos, Mexico.
[Ti] Título:Anticholinesterase activity and identification of huperzine A in three Mexican lycopods: Huperzia cuernavacensis, Huperzia dichotoma and Huperzia linifolia (Lycopodiaceae).
[So] Source:Pak J Pharm Sci;30(1 Suppl):235-239, 2017 Jan.
[Is] ISSN:1011-601X
[Cp] País de publicação:Pakistan
[La] Idioma:eng
[Ab] Resumo:Huperzine A (Hup A), the alkaloid produced by the Chinese medicinal plant Huperzia serrata, has been documented to be a promising agent for the treatment of Alzheimer's disease due to its potent acetylcholinesterase inhibitory (AChEI) activity. The search for anticholinesterase natural products, as well as for alternative sources of Hup A in Mexican lycopods, prompted us to investigate these plants. The action of methanolic and alkaloidal extracts of three Huperzia species (H. cuernavacensis, H. dichotoma, and H. linifolia) was evaluated using an in vitro anticholinesterase activity assay. Also, chromatographic and spectroscopic analyses were employed to detect the presence of Hup A. Methanolic and alkaloidal extracts of H. cuernavacensis showed IC =5.32±0.8µg/mL and 0.74±0.05µg/mL; H. dichotoma displayed AChEI with IC values =14.11±2.1µg/mL and 0.64±0.09µg/mL; and H. linifolia presented IC =158.37±8.7µg/mL and 4.2±1.24µg/mL, respectively, compared to the control Hup A (IC = 0.16±0.03µg/mL). Hup A was identified in the extracts of H. dichotoma, but it was not detected in the extracts of H. cuernavacensis and H. linifolia by H NMR techniques. This study reveals H. dichotoma as a new source of Hup A, and presents H. linifolia and H. cuernavacensis as potential candidates to obtain other anticholinesterase compounds useful in the Alzheimer's disease treatment.
[Mh] Termos MeSH primário: Acetilcolinesterase/metabolismo
Alcaloides/química
Alcaloides/farmacologia
Inibidores da Colinesterase/química
Inibidores da Colinesterase/farmacologia
Huperzia/química
Lycopodiaceae/química
Sesquiterpenos/química
Sesquiterpenos/farmacologia
[Mh] Termos MeSH secundário: Doença de Alzheimer/tratamento farmacológico
Extratos Vegetais/química
Extratos Vegetais/farmacologia
Plantas Medicinais/química
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Alkaloids); 0 (Cholinesterase Inhibitors); 0 (Plant Extracts); 0 (Sesquiterpenes); 0111871I23 (huperzine A); EC 3.1.1.7 (Acetylcholinesterase)
[Em] Mês de entrada:1707
[Cu] Atualização por classe:170713
[Lr] Data última revisão:
170713
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170620
[St] Status:MEDLINE


  2 / 61 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28526723
[Au] Autor:Yin X; Meicenheimer RD
[Ad] Endereço:Department of Botany, Miami University, 316 Pearson Hall, Oxford, Ohio 45056 USA yinx@miamioh.edu.
[Ti] Título:Anisotomous dichotomy results from an unequal bifurcation of the original shoot apical meristem in (Lycopodiaceae).
[So] Source:Am J Bot;104(5):782-786, 2017 May.
[Is] ISSN:1537-2197
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:PREMISE OF THE STUDY: Two types of dichotomy are recognized in Lycopodiaceae: isotomous (equal) and anisotomous (unequal). Anisotomous dichotomy (anisotomy) has been hypothesized to result from unequal growth of an equal bifurcation of the original shoot apical meristem (SAM). (Lycopodiaceae) exhibits anisotomy at various locations. We thus used to test this classic hypothesis about anisotomy. METHODS: Transverse areas of original and derived SAMs of anisotomy exhibited by the rhizome and the vertical aerial vegetative stem were measured using scanning electron microscopy. The difference between half of the original SAM and one derived SAM in terms of transverse area were compared using paired -tests. KEY RESULTS: During the anisotomy exhibited by the rhizome SAM, 77.4% of the transverse area of the original rhizome SAM contributed to the derived rhizome SAM. During the first anisotomy exhibited by the vertical aerial vegetative stem SAM, 66.2% of the transverse area of the original vertical aerial vegetative stem SAM contributed to the derived vertical aerial vegetative stem SAM. During the second anisotomy exhibited by the vertical aerial vegetative stem SAM, 49.4% of the transverse area of the original vertical aerial vegetative stem SAM contributed to the derived vertical aerial vegetative stem SAM. Nonetheless, the shape of the two derived SAMs differed though they did not differ in size. CONCLUSIONS: In , anisotomy results from an unequal bifurcation of the original SAM. This finding sheds light on plant body architecture evolution as well as plant organ (megaphyllous leaf) evolution.
[Mh] Termos MeSH primário: Lycopodiaceae/crescimento & desenvolvimento
Meristema/crescimento & desenvolvimento
Brotos de Planta/crescimento & desenvolvimento
[Mh] Termos MeSH secundário: Meristema/ultraestrutura
Microscopia Eletrônica de Varredura
Folhas de Planta/crescimento & desenvolvimento
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171019
[Lr] Data última revisão:
171019
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170521
[St] Status:MEDLINE
[do] DOI:10.3732/ajb.1700021


  3 / 61 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28390973
[Au] Autor:Li J; Xu PS; Tan LH; Zou ZX; Wang YK; Long HP; Zhou G; Li G; Xu KP; Tan GS
[Ad] Endereço:Xiangya Hospital of Central South University, Changsha 410008, PR China; Xiangya School of Pharmaceutical Sciences, Central South University, Changsha 410013, PR China.
[Ti] Título:Neolignans and serratane triterpenoids with inhibitory effects on xanthine oxidase from Palhinhaea cernua.
[So] Source:Fitoterapia;119:45-50, 2017 Jun.
[Is] ISSN:1873-6971
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:Three new neolignans, lycocernuasides B-D (1-3), three new serratane triterpenoids, lycernuic ketones D (8) and E (9), and lycernuic A (10), together with six known compounds, were isolated from the 75% aqueous EtOH extract of Palhinhaea cernua. Their structures and absolute configurations were established primarily by NMR, HRESIMS and circular dichroism (CD). All compounds were evaluated the inhibitory activities of xanthine oxidase. Compounds 1-3 displayed moderate inhibitory effects on xanthine oxidase with IC values of 30.36µM, 42.65µM and 35.33µM, respectively.
[Mh] Termos MeSH primário: Lignanas/química
Lycopodiaceae/química
Triterpenos/química
Xantina Oxidase/antagonistas & inibidores
[Mh] Termos MeSH secundário: Animais
Bovinos
Inibidores Enzimáticos/química
Inibidores Enzimáticos/isolamento & purificação
Lignanas/isolamento & purificação
Estrutura Molecular
Triterpenos/isolamento & purificação
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Enzyme Inhibitors); 0 (Lignans); 0 (Triterpenes); EC 1.17.3.2 (Xanthine Oxidase)
[Em] Mês de entrada:1706
[Cu] Atualização por classe:170615
[Lr] Data última revisão:
170615
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170410
[St] Status:MEDLINE


  4 / 61 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28039129
[Au] Autor:Yin X; Meicenheimer RD
[Ad] Endereço:Department of Botany, Miami University. 316 Pearson Hall, Oxford, Ohio 45056 USA.
[Ti] Título:The ontogeny, phyllotactic diversity, and discontinuous transitions of Diphasiastrum digitatum (Lycopodiaceae).
[So] Source:Am J Bot;104(1):8-23, 2017 Jan.
[Is] ISSN:1537-2197
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:PREMISE OF THE STUDY: Fibonacci phyllotactic patterns in seed plants are well documented, but whether such predominance holds true for lower vascular plants is relatively unknown. We investigated Diphasiastrum digitatum (Lycopodiaceae) phyllotaxis throughout its ontogeny to extend our knowledge of pattern frequency of lower vascular plants and to measure quantitative variables associated with discontinuous phyllotactic transitions. These investigations allowed us to test whether the same mechanisms inherent in shoot apical meristem (SAM) development of seed plants are applicable to early-diverged lower vascular plants SAM development. METHODS: Divergence angle, plastochron ratio, leaf insertion angle, circumferential ratio, radial ratio, half conic angle, area, circumference, and circularity of the shoot apical meristem were compared among different phyllotactic patterns and different meristem types observed throughout D. digitatum ontogeny, using scanning electron microscopy. KEY RESULTS: Fibonacci patterns were not predominant during six stages of D. digitatum ontogeny. In all five cases of discontinuous transition associated with strobili formation, divergence angle was the only variable that has changed consistently. CONCLUSIONS: The predominance of non-Fibonacci patterns/series in D. digitatum is inconsistent with the prediction of interpretive model of phyllotaxis. We hypothesize this is because its SAM, due to its frequent dichotomy, is not circular and primordia initiation is restricted spatially and temporally at the beginning of pattern formation. Change in divergence angle associated with discontinuous transitions is most likely due to the change of the location of new auxin maxima, due to the change of SAM shape and size.
[Mh] Termos MeSH primário: Lycopodiaceae/crescimento & desenvolvimento
Meristema/crescimento & desenvolvimento
Folhas de Planta/crescimento & desenvolvimento
Brotos de Planta/crescimento & desenvolvimento
Caules de Planta/crescimento & desenvolvimento
[Mh] Termos MeSH secundário: Algoritmos
Lycopodiaceae/ultraestrutura
Meristema/ultraestrutura
Microscopia Eletrônica de Varredura
Modelos Biológicos
Folhas de Planta/ultraestrutura
Brotos de Planta/ultraestrutura
Caules de Planta/ultraestrutura
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170815
[Lr] Data última revisão:
170815
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170101
[St] Status:MEDLINE
[do] DOI:10.3732/ajb.1600346


  5 / 61 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:27769820
[Au] Autor:Liu YC; Su J; Wu XD; Zhang ZJ; Fan M; Zhu QF; He J; Li XN; Peng LY; Cheng X; Zhao QS
[Ad] Endereço:State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204, PR China; University of the Chinese Academy of Sciences, Beijing 100049, PR China.
[Ti] Título:Five new Lycopodium alkaloids from the aerial parts of Phlegmariurus henryi.
[So] Source:Fitoterapia;115:148-154, 2016 Dec.
[Is] ISSN:1873-6971
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:A series of new Lycopodium alkaloids, namely 1-epi-malycorin A (1), 1-epi-17S-hydroxymalycorin A (2), 6α-hydroxyphlegmariurine A (3), 2S,4R-dihydroxyfawcettimine (4), and 16-hydroxylycodine (5), together with 24 known ones, have been isolated from the club moss Phlegmariurus henryi. The structures of the new compounds were determined by extensive spectroscopic analysis, including 1D and 2D NMR, as well as X-ray crystallographic analysis. Among them, the absolute configurations of 1, 2, and 4 and the structure of 3 were confirmed on the basis of the single-crystal X-ray diffraction analysis. 1-Epi-17S-hydroxymalycorin A (2) was a unique C N-type Lycopodium alkaloid consisting of a serratinine skeleton with 1,2-propanediol unit. 2S,4R-dihydroxyfawcettimine (4) was a 2,4-dihydroxy derivative of fawcettimine. 16-Hydroxylycodine (5) was the oxidative product of lycodine with an unusual hydroxymethyl group at C-15. All new compounds were evaluated for in vitro acetylcholinesterase (AChE) inhibitory activity and cytotoxicity against four human cancer cell lines.
[Mh] Termos MeSH primário: Alcaloides/química
Lycopodiaceae/química
[Mh] Termos MeSH secundário: Alcaloides/isolamento & purificação
Linhagem Celular Tumoral
Inibidores da Colinesterase/química
Seres Humanos
Indolizinas/química
Indolizinas/isolamento & purificação
Estrutura Molecular
Componentes Aéreos da Planta/química
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Alkaloids); 0 (Cholinesterase Inhibitors); 0 (Indolizines); 0 (fawcettimine); 5545-99-3 (serratinine)
[Em] Mês de entrada:1701
[Cu] Atualização por classe:170131
[Lr] Data última revisão:
170131
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161107
[St] Status:MEDLINE


  6 / 61 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:27576047
[Au] Autor:Tang Y; Xiong J; Zou Y; Zhang HY; Hu JF
[Ad] Endereço:Department of Natural Products Chemistry, School of Pharmacy, Fudan University, No. 826 Zhangheng Road, Shanghai, 201203, PR China.
[Ti] Título:Palhicerines A-F, Lycopodium alkaloids from the club moss Palhinhaea cernua.
[So] Source:Phytochemistry;131:130-139, 2016 Nov.
[Is] ISSN:1873-3700
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Four fawcettimine-type (palhicerines A-D, resp.) and two lycopodine-type (palhicerines E and F) Lycopodium alkaloids together with twenty known ones were isolated from the whole plant of Palhinhaea cernua. The structures and absolute configurations of the palhicerines A-F were determined by extensive spectroscopic methods, single-crystal X-ray diffraction analyses, chemical transformation, and electronic circular dichroism (ECD) calculations or induced electronic circular dichroism (IECD) spectra. Among the isolates, the new C/D-ring of the palhicerines A-C (trans-fused fawcettimine-type alkaloids) are rare, and each possesses a ß-oriented C-16 methyl group and a distinctive tertiary methoxy group at C-13. Chemotaxonomy for differentiating species in the genus Palhinhaea is briefly discussed.
[Mh] Termos MeSH primário: Alcaloides/isolamento & purificação
Lycopodiaceae/química
[Mh] Termos MeSH secundário: Alcaloides/química
Cristalografia por Raios X
Lycopodiaceae/genética
Conformação Molecular
Estrutura Molecular
Ressonância Magnética Nuclear Biomolecular
Quinolizinas/química
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Alkaloids); 0 (Quinolizines); 0 (fawcettimine); 0 (palhicerine A); 0 (palhicerine E); 2P5MU968XW (lycopodine)
[Em] Mês de entrada:1703
[Cu] Atualização por classe:170310
[Lr] Data última revisão:
170310
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160831
[St] Status:MEDLINE


  7 / 61 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:27012167
[Au] Autor:Shan SM; Luo JG; Pan K; Zou HY; Kong LY
[Ad] Endereço:Nanjing, People's Republic of China.
[Ti] Título:Rapid screening and identification of lycodine-type alkaloids in Lycopodiaceae and Huperziaceae plants by ultra-performance liquid chromatography coupled with quadrupole time-of-flight mass spectrometry.
[So] Source:Biomed Chromatogr;30(11):1861-1872, 2016 Nov.
[Is] ISSN:1099-0801
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Lycodine-type alkaloids have gained significant interest owing to their unique skeletal characteristics and acetylcholinesterase activity. This study established a rapid and reliable method using ultra-performance liquid chromatography coupled with electrospray ionization quadrupole time-of-flight tandem mass spectrometry (UPLC-ESI-Q/TOF-MS/MS) for comprehensive characterization of lycodine-type alkaloids for the first time. The lycodine-type alkaloids were detected successfully from Lycopodiastrum casuarinoides, Huperzia serrata and Phlegmarirus carinatus in seven plants of the Lycopodiaceae and Huperziaceae families, based on the established characteristic MS fragmentation of five known alkaloids. Furthermore, a total of 13 lycodine-type alkaloids were identified, of which three pairs of isomers were structurally characterized and differentiated. This study further improves mass analysis of lycodine-type alkaloids and demonstrates the superiority of UPLC with a high-resolution mass spectrometer for the rapid and sensitive structural elucidation of other trace active compounds. Copyright © 2016 John Wiley & Sons, Ltd.
[Mh] Termos MeSH primário: Alcaloides/análise
Cromatografia Líquida de Alta Pressão/métodos
Compostos Heterocíclicos de 4 ou mais Anéis/análise
Lycopodiaceae/química
Extratos Vegetais/química
[Mh] Termos MeSH secundário: Huperzia/química
Espectrometria de Massas por Ionização por Electrospray/métodos
Espectrometria de Massas em Tandem/métodos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Alkaloids); 0 (Heterocyclic Compounds, 4 or More Rings); 0 (Plant Extracts); 0 (lycodine)
[Em] Mês de entrada:1701
[Cu] Atualização por classe:170124
[Lr] Data última revisão:
170124
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160326
[St] Status:MEDLINE
[do] DOI:10.1002/bmc.3723


  8 / 61 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:26774122
[Au] Autor:Ciesla L; Okine M; Rosenberg A; Dossou KSS; Toll L; Wainer IW; Moaddel R
[Ad] Endereço:Laboratory of Clinical Investigation, National Institute on Aging, National Institutes of Health, Baltimore, MD 21224, United States; Department of Inorganic Chemistry, Medical University of Lublin, Chodzki 4A, 20-093 Lublin, Poland.
[Ti] Título:Development and characterization of the α3ß4α5 nicotinic receptor cellular membrane affinity chromatography column and its application for on line screening of plant extracts.
[So] Source:J Chromatogr A;1431:138-144, 2016 Jan 29.
[Is] ISSN:1873-3778
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:The α3ß4α5 nAChR has been recently shown to be a useful target for smoking cessation pharmacotherapies. Herein, we report on the development and characterization of the α3ß4α5 nicotinic receptor column by frontal displacement chromatography. The binding affinity of the nicotine and minor alkaloids found in tobacco smoke condensates were determined for both the α3ß4 and α3ß4α5 nicotinic receptors. It was demonstrated that while no subtype selectivity was observed for nicotine and nornicotine, anabasine was selective for the α3ß4α5 nicotinic receptor. The non-competitive inhibitor binding site was also studied and it was demonstrated while mecamylamine was not selective between subtypes, buproprion showed subtype selectivity for the α3ß4 nicotinic receptor. The application of this methodology to complex mixtures was then carried out by screening aqueous-alcoholic solutions of targeted plant extracts, including Lycopodium clavatum L. (Lycopodiaceae) and Trigonella foenum graecum L. (Fabaceae) against both the α3ß4 and α3ß4α5 nAChRs.
[Mh] Termos MeSH primário: Técnicas de Química Analítica/métodos
Cromatografia de Afinidade
Extratos Vegetais/química
Receptores Nicotínicos/química
[Mh] Termos MeSH secundário: Alcaloides/química
Anabasina/química
Sítios de Ligação
Fabaceae/química
Lycopodiaceae/química
Nicotina/análogos & derivados
Nicotina/química
Fumaça/análise
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, N.I.H., INTRAMURAL
[Nm] Nome de substância:
0 (Alkaloids); 0 (Plant Extracts); 0 (Receptors, Nicotinic); 0 (Smoke); 0 (nicotinic receptor alpha3beta4); 6M3C89ZY6R (Nicotine); 83H6L5QD8Z (nornicotine); LMS11II2LO (Anabasine)
[Em] Mês de entrada:1608
[Cu] Atualização por classe:170731
[Lr] Data última revisão:
170731
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160118
[St] Status:MEDLINE


  9 / 61 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
[PMID]:26882672
[Au] Autor:Tang Y; Xiong J; Hu JF
[Ti] Título:Lycopodium Alkaloids from Diphasiastrum complanatum.
[So] Source:Nat Prod Commun;10(12):2091-4, 2015 Dec.
[Is] ISSN:1934-578X
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:One new lycopodine-type Lycopodium alkaloid, dehydroisofawcettiine N-oxide (1) and eleven known analogues (2-12) were isolated from the whole plant of Diphasiastrum complanatum. The new structure was established on the basis of spectroscopic methods, including 2D NMR techniques. The absolute configurations of 2 and its new N-oxide derivative (1) were deduced by chemical transformation combined with Cotton effects in their electronic circular dichroism (ECD) spectra.
[Mh] Termos MeSH primário: Alcaloides/química
Compostos Heterocíclicos de 4 ou mais Anéis/química
Lycopodiaceae/química
[Mh] Termos MeSH secundário: Alcaloides/classificação
Estrutura Molecular
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Alkaloids); 0 (Heterocyclic Compounds, 4 or More Rings); 0 (dehydroisofawcettiine N-oxide)
[Em] Mês de entrada:1604
[Cu] Atualização por classe:161126
[Lr] Data última revisão:
161126
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160218
[St] Status:MEDLINE


  10 / 61 MEDLINE  
              first record previous record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:26363238
[Au] Autor:Reinaldo RC; Santiago AC; Medeiros PM; Albuquerque UP
[Ad] Endereço:Laboratory of Applied and Theoretical Ethnobiology. Department of Biology, Rural Federal University of Pernambuco, Rua Dom Manuel de Medeiros s/n, Dois Irmãos, 52171-900 Recife, PE, Brazil.
[Ti] Título:Do ferns and lycophytes function as medicinal plants? A study of their low representation in traditional pharmacopoeias.
[So] Source:J Ethnopharmacol;175:39-47, 2015 Dec 04.
[Is] ISSN:1872-7573
[Cp] País de publicação:Ireland
[La] Idioma:eng
[Ab] Resumo:ETHNOPHARMACOLOGICAL RELEVANCE: Ethnobotany is becoming an important tool for understanding how traditional medical systems are organized and which variables affect their structure and dynamics. However, some phenomena observed in ethnobotanical studies led us to question whether such phenomena are real or methodological artifacts. The small proportion of ferns and lycophytes in ethnobotanical surveys of medicinal plants is one such phenomenon, and its causes should be identified using different approach levels. The present study aimed to clarify the reasons for a low representation of these two groups in studies of medicinal plants. MATERIALS AND METHODS: The present study considered the following hypotheses: 1) ferns and lycophytes are little represented in different ethnobotanical studies because of inadequate data collection methods to record these species; 2) ferns and lycophytes are little represented because of the local perception of their low therapeutic efficacy; and 3) species of ferns and lycophytes are represented in local pharmacopoeias in proportion to the size of their families. We chose rural communities from Chapada do Araripe, Northeast Brazil to test our hypotheses. Data on the medicinal plant repertoires of the communities and on the perceived therapeutic efficacy of ferns were obtained using two different methods, semi-structured interviews associated with free lists and a checklist interview, both applied to local specialists. The resulting data were analyzed differently for each test. In addition, data regarding the total flora x medicinal flora ratio were obtained with a floristic survey and accessing data banks from previous studies performed by our research team. RESULTS: All hypotheses were confirmed, showing that all three factors contributed to the low representation of these plant groups as medicinal resources. The present study showed that free-list interviews are not a good method to access traditional knowledge of medicinal ferns and lycophytes and that the use of visual stimuli can help the memory of the informants, thus making it possible to associate the perceived characteristics with plant use. The results also showed that individuals perceive these plants as inferior therapeutic resources compared to angiosperms, which contributes to knowledge of their use not being transmitted. The final result of the present study was that the distribution of medicinal fern and lycophyte species within families was consistent with the total flora x medicinal flora ratio. This result indicates that even if the most appropriate data collection method was used for the ethnobotanical survey, the number of species would not be as expressive as that of angiosperms.
[Mh] Termos MeSH primário: Gleiquênias
Lycopodiaceae
Medicina Tradicional
Plantas Medicinais
[Mh] Termos MeSH secundário: Brasil
Feminino
Seres Humanos
Masculino
Farmacopeias como Assunto
Fitoterapia
Inquéritos e Questionários
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1610
[Cu] Atualização por classe:161230
[Lr] Data última revisão:
161230
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:150913
[St] Status:MEDLINE



página 1 de 7 ir para página                  
   


Refinar a pesquisa
  Base de dados : MEDLINE Formulário avançado   

    Pesquisar no campo  
1  
2
3
 
           



Search engine: iAH v2.6 powered by WWWISIS

BIREME/OPAS/OMS - Centro Latino-Americano e do Caribe de Informação em Ciências da Saúde