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Pesquisa : B01.650.940.800.575.912.250.044.666 [Categoria DeCS]
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[PMID]:28742251
[Au] Autor:Reidel RVB; Cioni PL; Majo L; Pistelli L
[Ad] Endereço:Dipartimento di Farmacia, Università di Pisa, Via Bonanno 6, 56126, Pisa, Italy.
[Ti] Título:Evolution of Volatile Emission in Rhus coriaria Organs During Different Stages of Growth and Evaluation of the Essential Oil Composition.
[So] Source:Chem Biodivers;14(11), 2017 Nov.
[Is] ISSN:1612-1880
[Cp] País de publicação:Switzerland
[La] Idioma:eng
[Ab] Resumo:Rhus coriaria, also known as Sumac, has been traditionally used in many countries as spice, condiment, dying agent, and medicinal herb. The chemical composition of essential oils (EOs) and the volatile emissions from different organs of this species collected in Sicily (Italy) were analyzed by gas chromatography-flame ionization detection and gas chromatography/mass spectrometry. Monoterpene and sesquiterpene hydrocarbons were the most abundant class in the volatile emissions with ß-caryophyllene and α-pinene were the main constituents in the majority of the examined samples. The EO composition was characterized by high amount of monoterpene and sesquiterpene hydrocarbons together with diterpenes. The main compounds in the EO obtained from the leaves and both stages of fruit maturation were cembrene and ß-caryophyllene, while α-pinene and tridecanoic acid were the key compounds in the flower EO. All the data were submitted to multivariate statistical analysis showing many differences among the different plant parts and their ontogenetic stages.
[Mh] Termos MeSH primário: Óleos Voláteis/análise
Rhus/química
Compostos Orgânicos Voláteis/análise
[Mh] Termos MeSH secundário: Análise por Conglomerados
Frutas/química
Frutas/metabolismo
Cromatografia Gasosa-Espectrometria de Massas
Monoterpenos/análise
Monoterpenos/isolamento & purificação
Óleos Voláteis/química
Folhas de Planta/química
Folhas de Planta/metabolismo
Raízes de Plantas/química
Raízes de Plantas/metabolismo
Caules de Planta/química
Caules de Planta/metabolismo
Análise de Componente Principal
Rhus/crescimento & desenvolvimento
Rhus/metabolismo
Sesquiterpenos/análise
Sesquiterpenos/isolamento & purificação
Microextração em Fase Sólida
Compostos Orgânicos Voláteis/química
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Monoterpenes); 0 (Oils, Volatile); 0 (Sesquiterpenes); 0 (Volatile Organic Compounds); BHW853AU9H (caryophyllene); JPF3YI7O34 (alpha-pinene)
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180112
[Lr] Data última revisão:
180112
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170726
[St] Status:MEDLINE
[do] DOI:10.1002/cbdv.201700270


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[PMID]:28764017
[Au] Autor:Wang S; Zhu F
[Ad] Endereço:Canadian Food and Wine Institute, Niagara College, 135 Taylor Road, Niagara-on-the-Lake, Ontario L0S 1J0, Canada; School of Chemical Sciences, University of Auckland, Private Bag 92019, Auckland 1142, New Zealand.
[Ti] Título:Chemical composition and biological activity of staghorn sumac (Rhus typhina).
[So] Source:Food Chem;237:431-443, 2017 Dec 15.
[Is] ISSN:0308-8146
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Staghorn sumac (Rhus typhina) is native to North America, and has been used by indigenous peoples for food and non-food applications for a long time. It has been adapted to the other parts of the world for cultivation as a potential source of functional food ingredients. This review summarises the updated information on the chemical composition and diverse biological activities of staghorn sumac. Various factors affect the chemical composition, function retention during processing, and nutritional properties of staghorn sumac-derived products. These factors include botanical characteristics and environmental conditions, extraction and quantification methods, and processing parameters. Various innovative and potential uses of staghorn sumac in food, nutraceutical and cosmetic industries are suggested on the basis of the chemical constituents. This review provides a scientific basis for the development of staghorn sumac as a sustainable economic plant for food and other industries.
[Mh] Termos MeSH primário: Rhus/química
[Mh] Termos MeSH secundário: Extratos Vegetais
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Nm] Nome de substância:
0 (Plant Extracts)
[Em] Mês de entrada:1711
[Cu] Atualização por classe:171106
[Lr] Data última revisão:
171106
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170803
[St] Status:MEDLINE


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[PMID]:28445505
[Au] Autor:Du N; Tan X; Li Q; Liu X; Zhang W; Wang R; Liu J; Guo W
[Ad] Endereço:Institute of Ecology and Biodiversity, School of Life Science, Shandong University, Jinan, Shandong Province, China.
[Ti] Título:Dominance of an alien shrub Rhus typhina over a native shrub Vitex negundo var. heterophylla under variable water supply patterns.
[So] Source:PLoS One;12(4):e0176491, 2017.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Temporal heterogeneity of a resource supply can have a profound effect on the interactions between alien and native plant species and their potential invasiveness. Precipitation patterns may be variable and result in a higher heterogeneity of water supply with global climate change. In this study, an alien shrub species, Rhus typhina, introduced to China from North America and a native shrub species, Vitex negundo var. heterophylla, were grown in monoculture and mixed culture under different water supply regimes, with four levels of water supply frequencies but with a constant level of total supplied water. After 60 days of treatments, the alien species was found to be the superior competitor in the mixed culture and was unaffected by changes in the water supply pattern. The dominance of R. typhina was mainly owing to its greater biomass and effective modulation of leaf physiology. However, in the mixed culture, V. negundo var. heterophylla exhibited both leaf- and whole-plant-level acclimations, including higher leaf length to petiole length and root to shoot biomass ratios, and lower specific leaf weight and leaf length to leaf width ratio. Plant height of V. negundo var. heterophylla was comparable to that of R. typhina in the mixed culture, which is a strategy to escape shading. Although water treatments had little effect on most traits in both species, the possible influence of water regimes should not be neglected. Compared with high-frequency water supply treatments, more individuals of V. negundo var. heterophylla died in low-water-frequency treatments when in competition with R. typhina, which may lead to species turnover in the field. The authors recommended that caution should be exercised when introducing R. typhina to non-native areas in the context of global climate change.
[Mh] Termos MeSH primário: Rhus/crescimento & desenvolvimento
Vitex/crescimento & desenvolvimento
[Mh] Termos MeSH secundário: Biomassa
Clorofila/metabolismo
Mudança Climática
Fluorometria
Espécies Introduzidas
Folhas de Planta/metabolismo
Raízes de Plantas/crescimento & desenvolvimento
Raízes de Plantas/fisiologia
Brotos de Planta/crescimento & desenvolvimento
Brotos de Planta/fisiologia
Solo/química
Abastecimento de Água
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Soil); 1406-65-1 (Chlorophyll)
[Em] Mês de entrada:1709
[Cu] Atualização por classe:171116
[Lr] Data última revisão:
171116
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170427
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0176491


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[PMID]:28388478
[Au] Autor:Zhou C; Huang M; Ren H; Yu J; Wu J; Ma X
[Ad] Endereço:College of Forestry, Fujian Agriculture and Forestry University, Fuzhou 350002, China. Electronic address: zhouchuifan@163.com.
[Ti] Título:Bioaccumulation and detoxification mechanisms for lead uptake identified in Rhus chinensis Mill. seedlings.
[So] Source:Ecotoxicol Environ Saf;142:59-68, 2017 Aug.
[Is] ISSN:1090-2414
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:A greenhouse experiment was conducted to assay the bioaccumulation and tolerance characteristics of Rhus chinensis Mill. to lead (Pb). The effects of exposing R. chinensis Mill seedlings to increasing Pb concentrations (0, 250, 500, 100mgkg-1) in the soil were assessed by measuring Pb accumulation, subcellular distribution, ultrastructure, photosynthetic characteristics, antioxidative enzyme activity, malondialdehyde content, and phytochelatin content. The majority of Pb taken up by R. chinensis Mill was associated with the cell wall fraction in the roots, where the absorption of Ca increased to maintain cell wall stability, and Pb deposits were found in the intercellular space or in the cell wall structures. In leaves, Pb was primarily stored in the cell wall, while it was compartmentalized into the vacuolar structures in the stem. Pb concentrations adversely affected the morphology of Rhus chinensis Mill cellular substructures. Furthermore, increased Peroxidase (POD) and catalase (CAT) activity was observed in plants grown in Pb-amended soil, and this may have led to reduced ROS to maintain the function of the membrane. Changes in phytochelatin levels (PCs) that were observed in Pb treated plants suggest that PCs formed complexes with Pb in the cytoplasm to reduce Pb toxicity in the metabolically active cellular compartment. This mechanism may allow for the plant to accumulate higher concentrations of toxic Pb and survive for a longer period of time. Our study provides a better understanding of how Rhus chinensis Mill detoxifies Pb.
[Mh] Termos MeSH primário: Chumbo/toxicidade
Rhus/efeitos dos fármacos
Plântulas/efeitos dos fármacos
Poluentes do Solo/toxicidade
Solo/química
[Mh] Termos MeSH secundário: Biodegradação Ambiental
Parede Celular/efeitos dos fármacos
Parede Celular/metabolismo
China
Inativação Metabólica
Chumbo/metabolismo
Malondialdeído/metabolismo
Fotossíntese/efeitos dos fármacos
Fitoquelatinas/metabolismo
Folhas de Planta/efeitos dos fármacos
Folhas de Planta/metabolismo
Raízes de Plantas/efeitos dos fármacos
Raízes de Plantas/metabolismo
Caules de Planta/efeitos dos fármacos
Caules de Planta/metabolismo
Rhus/metabolismo
Plântulas/metabolismo
Poluentes do Solo/metabolismo
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Soil); 0 (Soil Pollutants); 2P299V784P (Lead); 4Y8F71G49Q (Malondialdehyde); 98726-08-0 (Phytochelatins)
[Em] Mês de entrada:1709
[Cu] Atualização por classe:171116
[Lr] Data última revisão:
171116
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170408
[St] Status:MEDLINE


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[PMID]:28345446
[Au] Autor:Alam P; Parvez MK; Arbab AH; Siddiqui NA; Al-Dosary MS; Al-Rehaily AJ; Ahmed S; Kalam MA; Ahmad MS
[Ad] Endereço:a Department of Pharmacognosy , College of Pharmacy, King Saud University , Riyadh , Kingdom of Saudi Arabia.
[Ti] Título:Inter-species comparative antioxidant assay and HPTLC analysis of sakuranetin in the chloroform and ethanol extracts of aerial parts of Rhus retinorrhoea and Rhus tripartita.
[So] Source:Pharm Biol;55(1):1450-1457, 2017 Dec.
[Is] ISSN:1744-5116
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:CONTEXT: Extensive research on Rhus (Anacardiaceae) shows their antioxidant potential, which warrants further evaluation of its other species. OBJECTIVE: To perform a comparative antioxidant assay on extracts of R. retinorrhoea and R. tripartita, including sakuranetin quantification by a validated HPTLC method. MATERIALS AND METHODS: In vitro antioxidant assay was performed on chloroform and ethanol extracts of R. retinorrhoea Steud. ex Oliv. (RRCE and RREE) and R. tripartita (Ucria) Grande (RTCE and RTEE) by DPPH radical scavenging (at 31.25, 62.5, 125, 250 and 500 µg/mL concentrations) and ß-carotene-linoleic acid bleaching methods at 500 µg/mL concentration. Densitometric HPTLC method was developed and validated using toluene: ethyl acetate: methanol (8:2:0.2; v/v/v) as mobile phase, executed on glass-backed silica gel F plate and scanned at 292 nm. RESULTS: Antioxidant activity of Rhus extracts tested by the two methods (DPPH/BCB) was found in order of RTEE > RREE > RTCE > RRCE with IC 118.67/256.26, 315.75/82.35, 827.92/380.0 and 443.69/292.75, respectively. Scanning of the HPTLC plate provided an intense peak of sakuranetin at R = 0.59. The estimated sakuranetin content in the dry weight of the extracts was highest in RREE (27.95 µg/mg) followed by RRCE (25.22 µg/mg), RTEE (0.487 µg/mg) and RTCE (0.0 µg/mg). Presence of sakuranetin in RREE, RRCE and RTEE supported the highest antioxidant property of the two Rhus species. Nonetheless, low sakuratenin in R. tripartita indicated the presence of other bioactive constituents responsible for synergistic antioxidant activity. CONCLUSION: The developed HPTLC method therefore guarantees its application in quality control of commercialized herbal drugs and formulations containing sakuranetin.
[Mh] Termos MeSH primário: Antioxidantes/farmacologia
Clorofórmio/química
Cromatografia em Camada Delgada
Etanol/química
Flavonoides/farmacologia
Componentes Aéreos da Planta/química
Extratos Vegetais/farmacologia
Rhus/química
Solventes/química
[Mh] Termos MeSH secundário: Antioxidantes/química
Antioxidantes/isolamento & purificação
Compostos de Bifenilo/química
Flavonoides/química
Flavonoides/isolamento & purificação
Fitoterapia
Picratos/química
Extratos Vegetais/química
Extratos Vegetais/isolamento & purificação
Plantas Medicinais
Reprodutibilidade dos Testes
beta Caroteno/química
[Pt] Tipo de publicação:COMPARATIVE STUDY; JOURNAL ARTICLE; VALIDATION STUDIES
[Nm] Nome de substância:
0 (Antioxidants); 0 (Biphenyl Compounds); 0 (Flavonoids); 0 (Picrates); 0 (Plant Extracts); 0 (Solvents); 01YAE03M7J (beta Carotene); 3K9958V90M (Ethanol); 3O38P61299 (sakuranetin); 7V31YC746X (Chloroform); DFD3H4VGDH (1,1-diphenyl-2-picrylhydrazyl)
[Em] Mês de entrada:1706
[Cu] Atualização por classe:171116
[Lr] Data última revisão:
171116
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170328
[St] Status:MEDLINE
[do] DOI:10.1080/13880209.2017.1304428


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[PMID]:28274230
[Au] Autor:Tabassum S; Ahmed M; Mirza B; Naeem M; Zia M; Shanwari ZK; Khan GM
[Ad] Endereço:Department of Biotechnology, Faculty of Biological Sciences, Quaid-i-Azam University Islamabad, Islamabad, 45320, Pakistan.
[Ti] Título:Appraisal of phytochemical and in vitro biological attributes of an unexplored folklore: Rhus Punjabensis Stewart.
[So] Source:BMC Complement Altern Med;17(1):146, 2017 Mar 09.
[Is] ISSN:1472-6882
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: The role of plants for discovery of therapeutic potential accentuates the need to know their biological attributes. The present study aims to comprehend the biological attributes of Rhus punjabensis, an unexplored traditional medicinal plant. METHODS: Leaf and stem extracts of R. punjabensis prepared in 11 different organic solvents are evaluated for multimode antioxidant potential, total phenolic and flavonoid contents were determined through colorimetric assays, HPLC-DAD analysis was carried out for quantification of various polyphenols in extracts. Brine shrimp lethality, SRB and MTT assays were used to elucidate plant's cytotoxic and antileishmanial potentials. Disc diffusion assay was used to elucidate the protein kinase inhibitory, antibacterial and antifungal spectrum. RESULTS: Ethanol + ethyl acetate yielded maximum extract recovery from leaf (6.11 ± 1.09% w/w), total phenolic content (80.5 ± 2.18 µg GAE/mg extract) and reducing power potential (165.4 ± 2.29 µg AAE/mg extract). Maximum flavonoid content (30.50 ± 1.11 µg QE/mg extract) and highest DPPH based free radical scavenging activity (IC 11.4 ± 2.07) was exhibited by the methanol + chloroform leaf extract. The methanol extract showed maximum total antioxidant capacity (74.5 ± 2.25 µg AAE/mg DW), protein kinase inhibitory (12.5 ± 1.10 bald phenotype at 100 µg/disc) and antifungal (MIC = 25 µg/disc against Aspergillus flavus) potential. Reverse phase HPLC-DAD based quantification reveals presence of gallic acid, apigenin, rutin and catechin in various extracts. Brine shrimp lethality assay demonstrated most extracts as highly cytotoxic (LC < 50 µg/mL) whereas chloroform extract of leaf demonstrated maximuminhibition against human leukemia cell line (IC 7.80 ± 0.01 µg/mL). A significant activity against leishmanial promastigotes was demonstrated by n-hexane leaf extract (IC = 15.78 ± 0.15 µg/mL). A better antibacterial activity,by the extracts, against Gram positive strains as compared to Gram negative was observed. CONCLUSIONS: Results recommend multiple-solvent system as a critical factor to sumptuous the biological prospective of R. punjabensis and propose it to be a useful natural hub for the discovery of novel antioxidant, anticancer, antileishmanial and antimicrobial agents.
[Mh] Termos MeSH primário: Anti-Infecciosos
Antineoplásicos
Antioxidantes
Extratos Vegetais
Rhus
[Mh] Termos MeSH secundário: Animais
Anti-Infecciosos/farmacologia
Anti-Infecciosos/toxicidade
Antineoplásicos/farmacologia
Antineoplásicos/toxicidade
Antioxidantes/farmacologia
Antioxidantes/toxicidade
Artemia/efeitos dos fármacos
Bactérias/efeitos dos fármacos
Linhagem Celular Tumoral
Proliferação Celular/efeitos dos fármacos
Cromatografia Líquida de Alta Pressão
Flavonoides/farmacologia
Flavonoides/toxicidade
Seres Humanos
Leishmania/efeitos dos fármacos
Testes de Sensibilidade Microbiana
Fenóis/farmacologia
Fenóis/toxicidade
Extratos Vegetais/farmacologia
Extratos Vegetais/toxicidade
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Anti-Infective Agents); 0 (Antineoplastic Agents); 0 (Antioxidants); 0 (Flavonoids); 0 (Phenols); 0 (Plant Extracts)
[Em] Mês de entrada:1705
[Cu] Atualização por classe:170530
[Lr] Data última revisão:
170530
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170310
[St] Status:MEDLINE
[do] DOI:10.1186/s12906-017-1659-6


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[PMID]:28190465
[Au] Autor:Padmavathi G; Roy NK; Bordoloi D; Arfuso F; Mishra S; Sethi G; Bishayee A; Kunnumakkara AB
[Ad] Endereço:Cancer Biology Laboratory, Department of Biosciences and Bioengineering, Indian Institute of Technology, Guwahati, Assam 781 039, India.
[Ti] Título:Butein in health and disease: A comprehensive review.
[So] Source:Phytomedicine;25:118-127, 2017 Feb 15.
[Is] ISSN:1618-095X
[Cp] País de publicação:Germany
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: The risk of suffering from many chronic diseases seems to have made no improvement despite the advancement in medications available in the modern world. Moreover, the use of synthetic chemicals as medications has proved to worsen the scenario due to the various adverse side effects associated with them. PURPOSE: Extensive research on natural medicines provides ample evidence on the safety and efficacy of phytochemicals and nutraceuticals against diverse chronic ailments. Therefore, it is advisable to use natural products in the management of such diseases. This article aims to present a comprehensive and critical review of known pharmacological and biological effects of butein, an important chalcone polyphenol first isolated from Rhus verniciflua Stokes, implicated in the prevention and treatment of various chronic disease conditions. METHODS: An extensive literature search was conducted using PubMed, ScienceDirect, Scopus and Web of Science core collections using key words followed by evaluation of the bibliographies of relevant articles. RESULTS: Butein has been preclinically proven to be effective against several chronic diseases because it possesses a wide range of biological properties, including antioxidant, anti-inflammatory, anticancer, antidiabetic, hypotensive and neuroprotective effects. Furthermore, it has been shown to affect multiple molecular targets, including the master transcription factor nuclear factor-κB and its downstream molecules. Moreover, since it acts on multiple pathways, the chances of non-responsiveness and resistance development is reduced, supporting the use of butein as a preferred treatment option. CONCLUSION: Based on numerous preclinical studies, butein shows significant therapeutic potential against various diseases. Nevertheless, well-designed clinical studies are urgently needed to validate the preclinical findings.
[Mh] Termos MeSH primário: Anti-Inflamatórios/uso terapêutico
Anti-Hipertensivos/uso terapêutico
Antineoplásicos Fitogênicos/uso terapêutico
Antioxidantes/uso terapêutico
Chalconas/uso terapêutico
Fármacos Neuroprotetores/uso terapêutico
Extratos Vegetais/farmacologia
[Mh] Termos MeSH secundário: Anti-Inflamatórios/farmacologia
Anti-Hipertensivos/farmacologia
Antineoplásicos Fitogênicos/farmacologia
Chalcona/farmacologia
Chalcona/uso terapêutico
Chalconas/farmacologia
Seres Humanos
NF-kappa B/metabolismo
Fármacos Neuroprotetores/farmacologia
Fitoterapia
Extratos Vegetais/uso terapêutico
Polifenóis/farmacologia
Polifenóis/uso terapêutico
Rhus/química
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Nm] Nome de substância:
0 (Anti-Inflammatory Agents); 0 (Antihypertensive Agents); 0 (Antineoplastic Agents, Phytogenic); 0 (Antioxidants); 0 (Chalcones); 0 (NF-kappa B); 0 (Neuroprotective Agents); 0 (Plant Extracts); 0 (Polyphenols); 4WVS5M0LGF (butein); 5S5A2Q39HX (Chalcone)
[Em] Mês de entrada:1705
[Cu] Atualização por classe:170517
[Lr] Data última revisão:
170517
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170214
[St] Status:MEDLINE


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[PMID]:28111971
[Au] Autor:Neffati N; Aloui Z; Karoui H; Guizani I; Boussaid M; Zaouali Y
[Ad] Endereço:a Laboratoire d'Epidémiologie Moléculaire et Pathologie Expérimentale Appliquée aux Maladies Infectieuses (LR11IPT04) , Institut Pasteur de Tunis, Université de Tunis El Manar , Tunis , Tunisia.
[Ti] Título:Phytochemical composition and antioxidant activity of medicinal plants collected from the Tunisian flora.
[So] Source:Nat Prod Res;31(13):1583-1588, 2017 Jul.
[Is] ISSN:1478-6427
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Polyphenols, flavonoids and condensed tannins contents, as well as the antioxidant activity of the ethanolic and aqueous extracts obtained from aerial parts of 10 wild Tunisian plants, have been determined. Extracts showed appreciable levels of polyphenols and flavonoids, which reached 215.16 mg GAE g DW in Lavandula stoechas ethanolic extract, and 49.12 mg RE g DW in Thapsia garganica aqueous extract. The majority of tested extracts exhibited low total condensed tannins content, except for Rhus tripartitum and Periploca laevigata. The antioxidant activity tests showed great activity, especially for R. tripartitum and Lavandula multifida (IC = 5.16 and 5.1 µg mL , respectively). Canonical Correspondence Analysis revealed clear groupings of species according to the solvent used.
[Mh] Termos MeSH primário: Antioxidantes
Flavonoides/análise
Compostos Fitoquímicos
Extratos Vegetais/química
Plantas Medicinais/química
Polifenóis/análise
[Mh] Termos MeSH secundário: Antioxidantes/química
Etanol
Lavandula/química
Fenóis/análise
Proantocianidinas/análise
Rhus/química
Thapsia/química
Tunísia
Água
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Antioxidants); 0 (Flavonoids); 0 (Phenols); 0 (Phytochemicals); 0 (Plant Extracts); 0 (Polyphenols); 0 (Proanthocyanidins); 059QF0KO0R (Water); 3K9958V90M (Ethanol)
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170922
[Lr] Data última revisão:
170922
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170124
[St] Status:MEDLINE
[do] DOI:10.1080/14786419.2017.1280490


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[PMID]:28100074
[Au] Autor:Chen H; Wang C; Zhou H; Tao R; Ye J; Li W
[Ad] Endereço:a Institute of Chemical Industry of Forest Products , CAF , Nanjing , China.
[Ti] Título:Antioxidant capacity and identification of the constituents of ethyl acetate fraction from Rhus verniciflua Stokes by HPLC-MS.
[So] Source:Nat Prod Res;31(13):1573-1577, 2017 Jul.
[Is] ISSN:1478-6427
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Ethyl acetate fraction (EAF) from Rhus verniciflua Stokes is an important source of bioactive compounds. The aim of this study was the tentative identification and quantification of phenolic compounds, comparison of the phenolic structure-antioxidant activity relationships. Twelve compounds of EAF belonging to polyphenol types were detected by high performance liquid chromatography and analysed on line with negative ion electrospray ionisation tandem mass spectrometry, which were ethoxy 3-hydroxy benzoic acid, gallic acid (GA), 3,4-dihydroxy amygdalic acid, gallic acid cetyl ester, protocatechuic acid (PA), fustin, ethyl gallate (EG), garbanzol, fisetin, sulfuretin, butin and 3,7-dihydroxyflavanone-4'-rhamnoside. The antioxidant activity were evaluated based on the different types of radical scavenging capacities, i.e. DPPH·, ABTS·+ and OH. The antioxidant capacity of EAF mainly depended on the GA, EG, PA, fisetin, sulfuretin and butin. The phenolics exhibited a dose-dependent behaviour and high antioxidant ability.
[Mh] Termos MeSH primário: Antioxidantes/isolamento & purificação
Fenóis/farmacologia
Extratos Vegetais/química
Rhus/química
[Mh] Termos MeSH secundário: Acetatos
Antioxidantes/farmacologia
Benzofuranos/análise
Benzopiranos
Cromatografia Líquida de Alta Pressão
Flavonoides/análise
Depuradores de Radicais Livres
Fenóis/análise
Fenóis/química
Espectrometria de Massas por Ionização por Electrospray
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Acetates); 0 (Antioxidants); 0 (Benzofurans); 0 (Benzopyrans); 0 (Flavonoids); 0 (Free Radical Scavengers); 0 (Phenols); 0 (Plant Extracts); 0 (fustin); 492-14-8 (butin); 76845O8NMZ (ethyl acetate); M6410VY6MI (sulfuretin); OO2ABO9578 (fisetin)
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170922
[Lr] Data última revisão:
170922
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170120
[St] Status:MEDLINE
[do] DOI:10.1080/14786419.2016.1277353


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[PMID]:27626609
[Au] Autor:Suruga K; Hiruma W; Kadokura K; Tomita T; Miyata A; Sekino Y; Kimura M; Yamaguchi N; Murai T; Komatsu Y; Ono N
[Ad] Endereço:International Operation Department (FM Center for R & D), Kibun Foods Inc., Tokyo, Japan.
[Ti] Título:Antitumour and Apoptotic Effects of a Plant Extract Mixture Containing Rhus verniciflua and Other Herbs in Human Leukaemia Cells.
[So] Source:Drug Res (Stuttg);67(2):127-130, 2017 Feb.
[Is] ISSN:2194-9387
[Cp] País de publicação:Germany
[La] Idioma:eng
[Ab] Resumo:The apoptotic effects of a novel antitumour agent (Rv-PEM01) prepared from 6 kinds of herbs, including were investigated using flow cytometry and western blot analysis. Rv-PEM01 induced apoptosis but not necrosis in MOLT-3, KG-1, and K562 human leukaemia cell lines. Further, Rv-PEM01-treated cells showed significantly upregulated expression of caspase-3 and 9 and cleaved caspase-3 and 9 compared to the control cells. Taken together, the results suggest that Rv-PEM01 induced apoptosis via the mitochondrial-mediated pathway, and is a potential natural anticancer agent and/or a functional food material.
[Mh] Termos MeSH primário: Antineoplásicos/farmacologia
Apoptose/efeitos dos fármacos
Mitocôndrias/metabolismo
Extratos Vegetais/farmacologia
Rhus/química
[Mh] Termos MeSH secundário: Western Blotting
Caspase 3/metabolismo
Caspase 9/metabolismo
Citometria de Fluxo
Seres Humanos
Células K562
Transdução de Sinais
Regulação para Cima
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Antineoplastic Agents); 0 (Plant Extracts); EC 3.4.22.- (CASP3 protein, human); EC 3.4.22.- (CASP9 protein, human); EC 3.4.22.- (Caspase 3); EC 3.4.22.- (Caspase 9)
[Em] Mês de entrada:1703
[Cu] Atualização por classe:170308
[Lr] Data última revisão:
170308
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160915
[St] Status:MEDLINE
[do] DOI:10.1055/s-0042-113458



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