Base de dados : MEDLINE Pesquisa : B01.650.940.800.575.912.250.100.100 [Categoria DeCS] Referências encontradas : 1330 [refinar] Mostrando: 1 .. 10   no formato [Detalhado]

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[PMID]: 28741730 [Au] Autor: Yin G; Bai C; Sun J; Sun L; Xue Y; Zhang Y; Zhao H; Yu Z; Liu S; Zhang K [Ad] Endereço: Inner Mongolia Academy of Agriculture and Animal Husbandry Science, Hohhot, China. [Ti] Título: Fermentation quality and nutritive value of total mixed ration silages based on desert wormwood (Artemisia desertorum Spreng.) combining with early stage corn. [So] Source: Anim Sci J;88(12):1963-1969, 2017 Dec. [Is] ISSN: 1740-0929 [Cp] País de publicação: Australia [La] Idioma: eng [Ab] Resumo: This study aimed to investigate the fermentation quality and nutritive value of total mixed ration (TMR) silages based on desert wormwood (DW) combined with early stage corn (ESC) as forage and determine an optimum formula. Desert wormwood and ESC were harvested, chopped, and mixed with other ingredients according to a formula, packed into laboratory silos at densities of 500-550 g/L, and stored in the dark for 60 days. The DW proportions in the forage of TMR were 1, 0.75, 0.50, 0.25 and 0, based on fresh weight. As the proportion of DW decreased, the pH also decreased (P < 0.05), while lactic acid, lactic acid/acetic acid, crude protein, starch, and the in vitro digestibility of dry matter and neutral detergent fiber increased (P < 0.05). Ammonia nitrogen/total nitrogen in the TMR silages with DW proportions of 0.75, 0.25 and 0 in the forage was more than 10%. These results indicated that the quality of the TMR silage containing DW alone as forage was poor, TMR silages containing DW proportions of 0.75 and 0.25, and ESC alone, in the forage were not well preserved. The optimum TMR silage formula contained a DW proportion of 0.5 in the forage. [Mh] Termos MeSH primário: Artemisia Fermentação Valor Nutritivo Silagem Zea mays [Mh] Termos MeSH secundário: Acetatos/análise Amônia/análise Concentração de Íons de Hidrogênio Ácido Láctico/análise Nitrogênio/análise Proteínas/análise Silagem/análise Amido/análise Fatores de Tempo [Pt] Tipo de publicação: JOURNAL ARTICLE [Nm] Nome de substância: 0 (Acetates); 0 (Proteins); 33X04XA5AT (Lactic Acid); 7664-41-7 (Ammonia); 9005-25-8 (Starch); N762921K75 (Nitrogen) [Em] Mês de entrada: 1802 [Cu] Atualização por classe: 180227 [Lr] Data última revisão: 180227 [Sb] Subgrupo de revista: IM [Da] Data de entrada para processamento: 170726 [St] Status: MEDLINE [do] DOI: 10.1111/asj.12862

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[PMID]: 29337669 [Au] Autor: Kim JI; Park SW; Lim JJ; Sohn SI; Shin JS; Park SC; Jang YP; Chung EK; Lee HW; Lee KT [Ad] Endereço: 1Department of Pharmaceutical Biochemistry, College of Pharmacy, Kyung Hee University, 26, Kyungheedae-ro Dongdaemun-gu, Seoul, 02447, Korea Republic of. [Ti] Título: Gastroprotective effects of the isopropanol extract of Artemisia princeps and its gastroretentive floating tablets on gastric mucosal injury. [So] Source: Acta Pharm;67(4):479-494, 2017 Dec 20. [Is] ISSN: 1846-9558 [Cp] País de publicação: Croatia [La] Idioma: eng [Ab] Resumo: In this study, we investigated the gastroprotective effect of an isopropanol extract from the aerial parts of Artemisia princeps (IPAP) and developed a gastroretentive floating tablet of IPAP (IPAP-FR) for maximized local gastroprotective effects. Pre-treatment with IPAP ameliorated the gastric mucosal hemorrhagic lesions in ethanol/HCl- or indomethacin- treated rats. IPAP decreased mucosal hemorrhage of gastric ulcers induced by ethanol or indomethacin plus pyloric ligation in rats. The optimized floating tablet, IPAP-FR, floated on medium surface with more sustained eupatilin release compared to the non-floating control tablet. X-ray photographs in beagle dogs showed that IPAPFR was retained for > 2 h in the stomach. In the ethanol-induced gastric ulcer rat model, the gastric hemorrhagic lesion was improved more substantially with IPAP-FR compared to the non-floating control tablet. Based on these data, our data suggest that IPAP-FR has an improved therapeutic potential for the treatment of gastric ulcer. [Mh] Termos MeSH primário: Artemisia/química Mucosa Gástrica/efeitos dos fármacos Extratos Vegetais/farmacologia [Mh] Termos MeSH secundário: 2-Propanol Animais Antiulcerosos/farmacologia Cães Etanol/efeitos adversos Flavonoides/farmacologia Indometacina/efeitos adversos Ligadura/efeitos adversos Masculino Úlcera Péptica Hemorrágica/induzido quimicamente Úlcera Péptica Hemorrágica/etiologia Úlcera Péptica Hemorrágica/prevenção & controle Extratos Vegetais/administração & dosagem Ratos Ratos Sprague-Dawley Úlcera Gástrica/induzido quimicamente Úlcera Gástrica/complicações Úlcera Gástrica/prevenção & controle Comprimidos [Pt] Tipo de publicação: JOURNAL ARTICLE [Nm] Nome de substância: 0 (Anti-Ulcer Agents); 0 (Flavonoids); 0 (Plant Extracts); 0 (Tablets); 3K9958V90M (Ethanol); 4D58O05490 (eupatilin); ND2M416302 (2-Propanol); XXE1CET956 (Indomethacin) [Em] Mês de entrada: 1801 [Cu] Atualização por classe: 180131 [Lr] Data última revisão: 180131 [Sb] Subgrupo de revista: IM [Da] Data de entrada para processamento: 180117 [St] Status: MEDLINE

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[PMID]: 29188968 [Au] Autor: Koulu M; Örmä S; Liljeblad A; Niemelä P [Ti] Título: Artemisaiae as medicinal and herbal medicinal plants from ancient times to the present day. [So] Source: Duodecim;132(19):1763-70, 2016. [Is] ISSN: 0012-7183 [Cp] País de publicação: Finland [La] Idioma: eng [Ab] Resumo: The 2015 Nobel Prize in Physiology and Medicine was awarded to Chinese Youyou Tu for her work on an antimalarial drug that she isolated from sweet wormwood (Artemisia annua L) and absinthe (Artemisia absinthium L) belonging to the genus of Artemisia. In this article we deal with the use of Artemisiae as medicinal plants through the ages, and several pharmacologically active compounds can be obtained from species of the genus Artemisia. We will particularly focus on two medicinally interesting species of Artemisiae - sweet wormwood and absinthe - as well as two pharmacologically significant compounds found in them, artemisin and thujone. [Mh] Termos MeSH primário: Antimaláricos/farmacologia Artemisia Medicina Herbária Fármacos Neuroprotetores/farmacologia Extratos Vegetais/farmacologia [Mh] Termos MeSH secundário: Seres Humanos [Pt] Tipo de publicação: JOURNAL ARTICLE; REVIEW [Nm] Nome de substância: 0 (Antimalarials); 0 (Neuroprotective Agents); 0 (Plant Extracts) [Em] Mês de entrada: 1801 [Cu] Atualização por classe: 180108 [Lr] Data última revisão: 180108 [Sb] Subgrupo de revista: IM [Da] Data de entrada para processamento: 171201 [St] Status: MEDLINE

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[PMID]: 28977018 [Au] Autor: Song G; Li X; Hui R [Ad] Endereço: Shapotou Desert Research and Experimental Station, Northwest Institute of Eco-Environment and Resources, Chinese Academy of Science, Lanzhou, China. [Ti] Título: Effect of biological soil crusts on seed germination and growth of an exotic and two native plant species in an arid ecosystem. [So] Source: PLoS One;12(10):e0185839, 2017. [Is] ISSN: 1932-6203 [Cp] País de publicação: United States [La] Idioma: eng [Ab] Resumo: Biological soil crusts (BSCs) can improve the stability and health of native plant communities in arid ecosystems. However, it is unknown whether BSCs can also inhibit invasions of exotic vascular plants on stabilized reclaimed sand dunes. To answer this question, we conducted a greenhouse experiment to test the effects of cyanobacteria-dominated BSCs on 1) seed germination and biomass of an exotic grass (Stipa glareosa P. Smirn.), and 2) individual biomass of the exotic S. glareosa growing with two native plants, Eragrostis poaeoides Beauv. and Artemisia capillaris Thunb. Our experiment included three BSC treatments (intact crust, disturbed crust, and bare soil) and five species trials (native E. poaeoides alone, E. poaeoides mixed with exotic S. glareosa, native A. capillaris alone, A. capillaris mixed with exotic S. glareosa, and S. glareosa alone). The results showed that cyanobacteria-dominated crusts can significantly reduce the cumulative percent germination of the exotic grass (P<0.001) and native plants (P<0.001). Maximum cumulative percent germinations of the exotic grass and two native plants were found in bare soil, and minimum in intact crusts. The interaction of crust treatment × species trials on shoot biomass of the two native plants was significant (P<0.05). These results indicate that the presence of BSCs on stabilized sand dunes may reduce the germination of the exotic and two native plants. The effect of reducing exotic and native plant seeds germination would maintain more diverse plant communities and contribute to the formation of clumped vegetation patterns. We conclude that BSCs act as a natural regulator for vegetation patterns and thus promote ecosystem stability and sustainability. [Mh] Termos MeSH primário: Artemisia/crescimento & desenvolvimento Ecossistema Germinação Poaceae/crescimento & desenvolvimento Sementes/crescimento & desenvolvimento Solo [Mh] Termos MeSH secundário: Artemisia/embriologia Biomassa Cianobactérias/fisiologia Poaceae/embriologia Microbiologia do Solo [Pt] Tipo de publicação: JOURNAL ARTICLE [Nm] Nome de substância: 0 (Soil) [Em] Mês de entrada: 1711 [Cu] Atualização por classe: 171116 [Lr] Data última revisão: 171116 [Sb] Subgrupo de revista: IM [Da] Data de entrada para processamento: 171005 [St] Status: MEDLINE [do] DOI: 10.1371/journal.pone.0185839

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[PMID]: 28850890 [Au] Autor: Han B; Xin Z; Ma S; Liu W; Zhang B; Ran L; Yi L; Ren D [Ad] Endereço: Yunnan Food Safety Research Institute, Kunming University of Science and Technology, Kunming 650500, PR China. [Ti] Título: Comprehensive characterization and identification of antioxidants in Folium Artemisiae Argyi using high-resolution tandem mass spectrometry. [So] Source: J Chromatogr B Analyt Technol Biomed Life Sci;1063:84-92, 2017 Sep 15. [Is] ISSN: 1873-376X [Cp] País de publicação: Netherlands [La] Idioma: eng [Ab] Resumo: Antioxidants from natural sources, such as vegetables and fruits, are attracting more and more interest. In this work, we evaluated the antioxidant potential of Folium Artemisia Argyi, a traditional Chinese herb medicine and food supplement. The total phenolic content, total flavonoid content, and antioxidant ability of the crude extracts and fractions obtained from consecutively partition of n-hexane, ethyl acetate, and n-butanol were measured and compared. Ethyl acetate fraction shows the highest total phenolic and flavonoid contents and highest antioxidant capability with regard to DPPH, ABTS, superoxide anion free radical scavenging ability, and ferric-reducing antioxidant power. In addition, the potential antioxidant components were screened by DPPH-UHPLC-MS experiments and subsequently characterized by using high-resolution tandem mass spectrometry. This work finally identified 45 antioxidants, including organic acids, phenolic compounds, flavonoids, and methoxylated flavonoids. The results suggested that Folium Artemisiae Argyi is a potential inexpensive resource of natural antioxidants. [Mh] Termos MeSH primário: Antioxidantes/análise Artemisia/química Medicamentos de Ervas Chinesas/química Espectrometria de Massas em Tandem/métodos [Mh] Termos MeSH secundário: Antioxidantes/química Ácidos Carboxílicos/análise Ácidos Carboxílicos/química Cromatografia Líquida de Alta Pressão/métodos Flavonoides/análise Flavonoides/química Fenóis/análise Fenóis/química Umbeliferonas/análise Umbeliferonas/química [Pt] Tipo de publicação: JOURNAL ARTICLE [Nm] Nome de substância: 0 (Antioxidants); 0 (Carboxylic Acids); 0 (Drugs, Chinese Herbal); 0 (Flavonoids); 0 (Phenols); 0 (Umbelliferones); SM2XD6V944 (esculetin) [Em] Mês de entrada: 1710 [Cu] Atualização por classe: 171002 [Lr] Data última revisão: 171002 [Sb] Subgrupo de revista: IM [Da] Data de entrada para processamento: 170830 [St] Status: MEDLINE

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[PMID]: 28841693 [Au] Autor: Zhang A; Wang D; Li J; Gao F; Fan X [Ad] Endereço: Xinjiang Key Laboratory of Biological Resources and Genetic Engineering, College of Life Science and Technology, Xinjiang University, Urumqi, China. [Ti] Título: The effect of aqueous extract of Xinjiang Artemisia rupestris L. (an influenza virus vaccine adjuvant) on enhancing immune responses and reducing antigen dose required for immunity. [So] Source: PLoS One;12(8):e0183720, 2017. [Is] ISSN: 1932-6203 [Cp] País de publicação: United States [La] Idioma: eng [Ab] Resumo: Potent adjuvant can improve the effectiveness of vaccines and reduce the antigen doses required for initiating the protective immunity. In this study, we identified that aqueous extract of Artemisia rupestris L. (AEAR) could be employed as an efficient adjuvant for influenza virus vaccine (V) to enhance immune responses and reduce the antigen doses required for initiating immunity, without compromising the immune response. ICR mice were subcutaneously co-administrated with V combined with different concentrations of AEAR demonstrated that 300 µg AEAR could significantly improve hemagglutination inhibition (HI) and increase IgG antibody titers in serum (P<0.05) and the population of CD4+CD44+ and CD8+CD44+ (P<0.05). Next, 300 µg AEAR combined with different doses of V in vivo markedly increased HI and specific IgG antibody level(P<0.05). It also significantly increased the amount of CD4+ and CD8+ T cells, CD4+CD44+ and CD8+CD44+ T cells (P<0.05), improved lymphocyte proliferation, the secretion of CD4+IL-4, CD4+IFN-γ and CD8+IFN-γ (P<0.05), and the killing efficacy of cytotoxic T lymphocyte (CTL) (P<0.05). Furthermore, the combination increased the expression of major histocompatibility complex-II (MHC-II) and co-stimulatory molecules including CD40, CD80, and CD86 on dendritic cells (DCs), and downregulated the expression of CD25+Foxp3+Treg cells (P<0.05). No significant difference was observed between high-dose V and low-dose AEAR-V (10-fold lower) vaccination group (P>0.05), indicating a 10-fold reduction of antigen required for V vaccine administration. In conclusion, this study demonstrated that AEAR, as an adjuvant for influenza vaccine, could stimulate potent humoral and cellular immune responses and reduce the antigen dose required for effective vaccination, which were mediated by promoting DCs activation and repressing Treg expression. [Mh] Termos MeSH primário: Adjuvantes Imunológicos/farmacologia Antígenos/administração & dosagem Artemisia/química Extratos Vegetais/farmacologia [Mh] Termos MeSH secundário: Proliferação Celular Citocinas/metabolismo Citotoxicidade Imunológica Relação Dose-Resposta Imunológica Ensaio de Imunoadsorção Enzimática Imunoglobulina G/sangue Linfócitos T/citologia Linfócitos T/imunologia Água [Pt] Tipo de publicação: JOURNAL ARTICLE [Nm] Nome de substância: 0 (Adjuvants, Immunologic); 0 (Antigens); 0 (Cytokines); 0 (Immunoglobulin G); 0 (Plant Extracts); 059QF0KO0R (Water) [Em] Mês de entrada: 1710 [Cu] Atualização por classe: 171026 [Lr] Data última revisão: 171026 [Sb] Subgrupo de revista: IM [Da] Data de entrada para processamento: 170826 [St] Status: MEDLINE [do] DOI: 10.1371/journal.pone.0183720

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[PMID]: 28711019 [Au] Autor: Baghbani-Arani F; Movagharnia R; Sharifian A; Salehi S; Shandiz SAS [Ad] Endereço: Department of Genetics and Biotechnology, School of Biological Science, Varamin-Pishva Branch, Islamic Azad University, Varamin, Iran. [Ti] Título: Photo-catalytic, anti-bacterial, and anti-cancer properties of phyto-mediated synthesis of silver nanoparticles from Artemisia tournefortiana Rchb extract. [So] Source: J Photochem Photobiol B;173:640-649, 2017 Aug. [Is] ISSN: 1873-2682 [Cp] País de publicação: Switzerland [La] Idioma: eng [Ab] Resumo: Metal nanoparticles have largely been investigated due to their potential medicinal activities. This study demonstrates the biological properties of green-synthesized silver nanoparticles (AgNPs) by using Artemisia tournefortiana Rchb ethanol extract. Instrumentations such as ultraviolet-visible spectra analysis, high-resolution transmission electron microscopy, scanning electron microscopy, energy-dispersive X-ray analysis, X-ray diffraction, and Fourier transform infrared spectroscopy were used to reveal the synthesized AgNPs. Microscopic results showed that the particles were mostly spherical in shape, having an average diameter of 22.89±14.82nm. The antibacterial activity of the phyto-fabricated AgNPs was investigated by the determination of minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC). The in vitro cytotoxicity effect was investigated against normal human embryonic kidney (HEK293) cells and human colon adenocarcinoma cancer (HT29) cells. The apoptotic cells were identified by annexin V/PI FITC staining, and morphological assessment. The expressions of Bax and Bcl2 were evaluated by quantitative real time PCR method. The phyto-synthesized AgNPs have shown increased cell apoptosis and demonstrated dose-dependent cytotoxicity in HT29 cancer cells. Moreover, the photocatalytic activity of the phyto-synthesized AgNPs was evaluated by degradation of Coomassie Brilliant Blue G-250 under UV light exposure and these fabricated Ag nanoparticles demonstrated efficacy in degrading the dye within 60min. Overall, the present results highlighted the antibacterial and anticancer properties of fabricated AgNPs, suggesting that phyto-synthesized silver nanoparticles could possess potent anti-pathogenic bacteria and anti-colon cancer activities. [Mh] Termos MeSH primário: Antibacterianos/síntese química Antineoplásicos/síntese química Artemisia/química Nanopartículas Metálicas/química Prata/química [Mh] Termos MeSH secundário: Antibacterianos/química Antibacterianos/farmacologia Antineoplásicos/química Antineoplásicos/toxicidade Artemisia/metabolismo Catálise Sobrevivência Celular/efeitos dos fármacos Expressão Gênica/efeitos dos fármacos Bactérias Gram-Negativas/efeitos dos fármacos Bactérias Gram-Positivas/efeitos dos fármacos Química Verde Células HEK293 Células HT29 Seres Humanos Nanopartículas Metálicas/uso terapêutico Nanopartículas Metálicas/toxicidade Testes de Sensibilidade Microbiana Microscopia Eletrônica de Transmissão Microscopia de Fluorescência Fotólise/efeitos da radiação Extratos Vegetais/química Folhas de Planta/química Folhas de Planta/metabolismo Proteínas Proto-Oncogênicas c-bcl-2/genética Proteínas Proto-Oncogênicas c-bcl-2/metabolismo Corantes de Rosanilina/química Espectroscopia de Infravermelho com Transformada de Fourier Raios Ultravioleta Difração de Raios X Proteína X Associada a bcl-2/genética Proteína X Associada a bcl-2/metabolismo [Pt] Tipo de publicação: JOURNAL ARTICLE [Nm] Nome de substância: 0 (Anti-Bacterial Agents); 0 (Antineoplastic Agents); 0 (Plant Extracts); 0 (Proto-Oncogene Proteins c-bcl-2); 0 (Rosaniline Dyes); 0 (bcl-2-Associated X Protein); 3M4G523W1G (Silver); M1ZRX790SI (coomassie Brilliant Blue) [Em] Mês de entrada: 1710 [Cu] Atualização por classe: 171010 [Lr] Data última revisão: 171010 [Sb] Subgrupo de revista: IM [Da] Data de entrada para processamento: 170716 [St] Status: MEDLINE

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[PMID]: 28635610 [Au] Autor: Saoudi M; Ncir M; Ben Ali M; Grati M; Jamoussi K; Allouche N; El Feki A [Ad] Endereço: Laboratory of Animal Ecophysiology, Sciences Faculty, University of Sfax, Sfax, Tunisia. mongifss@yahoo.fr. [Ti] Título: Chemical components, antioxidant potential and hepatoprotective effects of Artemisia campestris essential oil against deltamethrin-induced genotoxicity and oxidative damage in rats. [So] Source: Gen Physiol Biophys;36(3):331-342, 2017 Jul. [Is] ISSN: 0231-5882 [Cp] País de publicação: Slovakia [La] Idioma: eng [Ab] Resumo: In the present study, we evaluated the antioxidant potential of Artemisia campestris essential oil (ACEO) and the possible protective effects against deltamethrin induced hepatic toxic effects. The ACEO showed radical scavenging activity with IC50 = 47.66 ± 2.51 µg/ml, ferric reducing antioxidant power (FRAP) potential (EC50 = 5.36 ± 0.77 µg/ml), superoxide scavenging activity (IC50 = 0.175 ± 0.007 µg/ml) and Ë™OH scavenging activity (IC50 = 0.034 ± 0.007 µg/ml). The obtained results of phenolic profile demonstrated that phenolic compounds are the major contributor to the antioxidant activity of ACEO. GC-MS analysis revealed the presence of 61 components in which monoterpene hydrocarbons constitute the major fraction (38.85%). In in vivo study, deltamethrin exposure caused an increase of serum AST, ALT and ALP activities, hepatic malondialdehyde (MDA) (measured as TBARS) and conjugated dienes markers of lipid peroxidation (LPO), while antioxidant enzyme activities (SOD, CAT and GPx) decreased significantly. Furthermore, it induces DNA damage as indicated by DNA fragmentation accompanied with severe histological changes in the liver tissues. The treatment with vitamin E or ACEO significantly improved the hepatic toxicity induced by deltamethrin. It can be concluded that vitamin E and ACEO are able to improve the hepatic oxidative damage induced by deltamethrin. Therefore, ACEO is an important product in reducing the toxic effects of deltamethrin. [Mh] Termos MeSH primário: Artemisia/química Doença Hepática Induzida por Substâncias e Drogas/tratamento farmacológico Doença Hepática Induzida por Substâncias e Drogas/fisiopatologia Dano ao DNA/efeitos dos fármacos Nitrilos/envenenamento Óleos Voláteis/administração & dosagem Piretrinas/envenenamento [Mh] Termos MeSH secundário: Animais Antioxidantes/administração & dosagem Doença Hepática Induzida por Substâncias e Drogas/etiologia Citoproteção/efeitos dos fármacos Relação Dose-Resposta a Droga Inseticidas/envenenamento Masculino Estresse Oxidativo/efeitos dos fármacos Extratos Vegetais/administração & dosagem Ratos Ratos Wistar Espécies Reativas de Oxigênio/metabolismo Resultado do Tratamento [Pt] Tipo de publicação: JOURNAL ARTICLE [Nm] Nome de substância: 0 (Antioxidants); 0 (Insecticides); 0 (Nitriles); 0 (Oils, Volatile); 0 (Plant Extracts); 0 (Pyrethrins); 0 (Reactive Oxygen Species); 2JTS8R821G (decamethrin) [Em] Mês de entrada: 1709 [Cu] Atualização por classe: 170912 [Lr] Data última revisão: 170912 [Sb] Subgrupo de revista: IM [Da] Data de entrada para processamento: 170622 [St] Status: MEDLINE [do] DOI: 10.4149/gpb_2016057

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[PMID]: 28573232 [Au] Autor: Shahat AA; Mahmoud EA; Al-Mishari AA; Alsaid MS [Ad] Endereço: Pharmacognosy Department, College of Pharmacy, King Saud University P.O. Box 2457, Riyadh 11451. [Ti] Título: ANTIMICROBIAL ACTIVITIES OF SOME SAUDI ARABIAN HERBAL PLANTS. [So] Source: Afr J Tradit Complement Altern Med;14(2):161-165, 2017. [Is] ISSN: 2505-0044 [Cp] País de publicação: Nigeria [La] Idioma: eng [Ab] Resumo: BACKGROUND: Several edible plants are used in Kingdom of Saudi Arabia since early time to control microbial infections. In the present study, twenty-four Saudi Arabian medicinal plants d according to traditionally used were select and investigated for the antimicrobial activities. MATERIALS AND METHODS: This study was designed at evaluating the antimicrobial activities of the methanol extracts of twenty-four species of sixteen plant families used in the traditional medicine by Saudi Arabian people for the treatment of numerous ailments of the microbial and non-microbial origin against four Gram-positive, four Gram-negative bacteria and four fungi and yeast using the agar well diffusion method. RESULTS: Of most of the plants tested were found to be active against two to eight organisms. Five plants were active against eight organisms. The data appeared that extracts of (SY-176), (SY- (SY-181), (SY-188), (SY-197) and (SY-198) have anti-microbial activity against the most of tested bacteria, fungi and yeast. Whereas (SY-, the extracts of (SY-175), (SY-187), and (SY-195) have poor action against the tested bacteria, fungi and yeast. CONCLUSION: The antimicrobial activity of plant extracts against bacteria was more effective than against fungi. [Mh] Termos MeSH primário: Antibacterianos/farmacologia Antifúngicos/farmacologia Bactérias/efeitos dos fármacos Fungos/efeitos dos fármacos Magnoliopsida Extratos Vegetais/farmacologia Plantas Medicinais [Mh] Termos MeSH secundário: Artemisia Bactérias/crescimento & desenvolvimento Echium Fungos/crescimento & desenvolvimento Testes de Sensibilidade Microbiana Resedaceae Rumex Arábia Saudita Ziziphus [Pt] Tipo de publicação: JOURNAL ARTICLE [Nm] Nome de substância: 0 (Anti-Bacterial Agents); 0 (Antifungal Agents); 0 (Plant Extracts) [Em] Mês de entrada: 1708 [Cu] Atualização por classe: 171116 [Lr] Data última revisão: 171116 [Sb] Subgrupo de revista: IM [Da] Data de entrada para processamento: 170603 [St] Status: MEDLINE [do] DOI: 10.21010/ajtcam.v14i2.17

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[PMID]: 28530200 [Au] Autor: Ghanbar F; Mirzaie A; Ashrafi F; Noorbazargan H; Dalirsaber Jalali M; Salehi S; Sadat Shandiz SA [Ad] Endereço: Department of Biology, Tehran North Branch, Islamic Azad University, Tehran, Iran. [Ti] Título: Antioxidant, antibacterial and anticancer properties of phyto synthesised Podlech extract mediated AgNPs. [So] Source: IET Nanobiotechnol;11(4):485-492, 2017 Jun. [Is] ISSN: 1751-8741 [Cp] País de publicação: England [La] Idioma: eng [Ab] Resumo: The focus of this study is on a rapid and cost-effective approach for the synthesis of silver nanoparticles (AgNPs) using Podlech aerial parts extract and assessment of their antioxidant, antibacterial and anticancer activities. The prepared AgNPs were determined by ultraviolet-visible spectroscopy, X-ray diffraction, Fourier transform infra-red spectroscopy, transmission electron microscopy, scanning electron microscopy, energy-dispersive spectroscopy, and dynamic light scattering and zeta-potential analysis. The AgNPs and extract were evaluated for their antiradical scavenging activity by 2, 2-diphenyl, 1-picryl hydrazyl assay and anticancer activity against colon cancer (human colorectal adenocarcinoma cell line 29) compared with normal human embryonic kidney (HEK293) cells. Also, the prepared AgNPs were studied for its antibacterial activity. The AgNPs revealed a higher antioxidant activity compared with extract alone. The phyto-synthesised AgNPs and extract showed a dose-response cytotoxicity effect against HT29 and HEK293 cells. As evidenced by Annexin V/propidium iodide staining, the number of apoptotic HT29 cells was significantly enhanced, following treatment with AgNPs as compared with untreated cells. Besides, the antibacterial property of the AgNPs indicated a significant effect against the selected pathogenic bacteria. These present obtained results show the potential applications of phyto-synthesised AgNPs using aerial parts extract. [Mh] Termos MeSH primário: Antibacterianos/administração & dosagem Antifúngicos/administração & dosagem Antineoplásicos/administração & dosagem Artemisia/química Sobrevivência Celular/efeitos dos fármacos Nanopartículas Metálicas/administração & dosagem Prata/administração & dosagem [Mh] Termos MeSH secundário: Antibacterianos/síntese química Antifúngicos/síntese química Antineoplásicos/síntese química Fenômenos Fisiológicos Bacterianos/efeitos dos fármacos Relação Dose-Resposta a Droga Composição de Medicamentos/métodos Fungos/efeitos dos fármacos Células HEK293 Células HT29 Células HeLa Seres Humanos Células MCF-7 Teste de Materiais Nanopartículas Metálicas/química Nanopartículas Metálicas/ultraestrutura Tamanho da Partícula Fotoquímica/métodos Extratos Vegetais/administração & dosagem Extratos Vegetais/química Prata/química Resultado do Tratamento [Pt] Tipo de publicação: JOURNAL ARTICLE [Nm] Nome de substância: 0 (Anti-Bacterial Agents); 0 (Antifungal Agents); 0 (Antineoplastic Agents); 0 (Plant Extracts); 3M4G523W1G (Silver) [Em] Mês de entrada: 1708 [Cu] Atualização por classe: 170817 [Lr] Data última revisão: 170817 [Sb] Subgrupo de revista: IM [Da] Data de entrada para processamento: 170523 [St] Status: MEDLINE [do] DOI: 10.1049/iet-nbt.2016.0101

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