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[PMID]: | 27630101 |
[Au] Autor: | Govindarajan M; Benelli G |
[Ad] Endereço: | Department of Zoology, Unit of Vector Control, Phytochemistry and Nanotechnology, Annamalai University, Annamalainagar, 608 002, Tamil Nadu, India. drgovind1979@gmail.com. |
[Ti] Título: | Artemisia absinthium-borne compounds as novel larvicides: effectiveness against six mosquito vectors and acute toxicity on non-target aquatic organisms. |
[So] Source: | Parasitol Res;115(12):4649-4661, 2016 Dec. | [Is] ISSN: | 1432-1955 |
[Cp] País de publicação: | Germany |
[La] Idioma: | eng |
[Ab] Resumo: | The eco-friendly control of mosquito vectors is a crucial challenge of public health importance. Here we evaluated the larvicidal potential of Artemisia absinthium essential oil (EO) and its three major chemical constituents against six mosquito vectors: Anopheles stephensi, Anopheles subpictus, Aedes aegypti, Aedes albopictus, Culex quinquefasciatus, and Culex tritaeniorhynchus. The EO was obtained by leaf hydro-distillation. Its chemical composition was analyzed using gas chromatography-mass spectrometry. Major components were (E)-ß-farnesene (31.6 %), (Z)-en-yn-dicycloether (11.12 %), and (Z)-ß-ocimene (27.8 %). The EO was toxic effect against larval populations of An. stephensi, An. subpictus, Ae. aegypti, Ae. albopictus, Cx. quinquefasciatus, and Cx. tritaeniorhynchus, with LC values of 41.85, 52.02, 46.33, 57.57, 50.57, and 62.16 µg/ml. (E)-ß-farnesene, (Z)-en-yn-dicycloether, and (Z)-ß-ocimene were highly effective on An. stephensi (LC = 8.13, 16.24 and 25.84 µg/ml) followed by An. subpictus (LC = 10.18, 20.99, and 30.86 µg/ml), Ae. aegypti (LC = 8.83,17.66, and 28.35 µg/ml), Ae. albopictus (LC = 11.38,23.47, and 33.72 µg/ml), Cx. quinquefasciatus (LC = 9.66, 19.76, and 31.52 µg/ml), and Cx. tritaeniorhynchus (LC = 12.51,25.88, and 37.13 µg/ml). Notably, the EO and its major compounds were safer to the non-target organisms Chironomous circumdatus, Anisops bouvieri and Gambusia affinis, with LC values ranging from 207.22 to 4385 µg/ml. Overall, our results highlight that (E)-ß-farnesene, (Z)-en-yn-dicycloether, and (Z)-ß-ocimene from the A. absinthium EO represent promising eco-friendly larvicides against six key mosquito vectors with moderate toxicity against non-target organisms. |
[Mh] Termos MeSH primário: |
Artemisia absinthium/química Inseticidas/isolamento & purificação Extratos Vegetais/farmacologia
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[Mh] Termos MeSH secundário: |
Aedes/efeitos dos fármacos Alcenos Animais Anopheles/efeitos dos fármacos Organismos Aquáticos Culex/efeitos dos fármacos Feminino Cromatografia Gasosa-Espectrometria de Massas Larva/efeitos dos fármacos Controle de Mosquitos/métodos Mosquitos Vetores/efeitos dos fármacos Óleos Voláteis Extratos Vegetais/isolamento & purificação Folhas de Planta/química Sesquiterpenos
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[Pt] Tipo de publicação: | JOURNAL ARTICLE |
[Nm] Nome de substância:
| 0 (Alkenes); 0 (Insecticides); 0 (Oils, Volatile); 0 (Plant Extracts); 0 (Sesquiterpenes); 13877-91-3 (beta-ocimene); 18794-84-8 (beta-farnesene); 8008-93-3 (absinthium) |
[Em] Mês de entrada: | 1705 |
[Cu] Atualização por classe: | 171007 |
[Lr] Data última revisão:
| 171007 |
[Sb] Subgrupo de revista: | IM |
[Da] Data de entrada para processamento: | 160916 |
[St] Status: | MEDLINE |
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