Base de dados : MEDLINE
Pesquisa : B01.650.940.800.575.912.250.100.800 [Categoria DeCS]
Referências encontradas : 507 [refinar]
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[PMID]:28657132
[Au] Autor:Ahmed S; Ahmad MS; Yousaf M; Nur-E-Alam M; Al-Rehaily AJ
[Ad] Endereço:Department of Pharmacognosy, College of Pharmacy, King Saud University, P.O. Box 2457, Riyadh, 11451, Saudi Arabia.
[Ti] Título:Two New Sesquiterpene Alcohols Isolated from Senecio hadiensis Forssk. Grown in Saudi Arabia.
[So] Source:Chem Biodivers;14(9), 2017 Sep.
[Is] ISSN:1612-1880
[Cp] País de publicação:Switzerland
[La] Idioma:eng
[Ab] Resumo:Phytochemical investigation on the aerial parts of Senecio hadiensis Forssk. led to the isolation of two new sesquiterpenoids, presilphiperfolan-2α,5α,8α-triol (1) and presilphiperfolan-2α,5α,8α,10α-tetraol (2) featuring the rare presilphiperfolane-type frameworks. The structures of 1 and 2 were elucidated on the basis of extensive spectroscopic (1D- and 2D-NMR, HR-ESI-MS) methods and by comparison with the literature data. The isolates 1 and 2 were evaluated in-vitro for antiinflammatory, cytotoxic, and peroxisome proliferator activated receptor alpha and gamma (PPARα and PPARγ) agonistic activities.
[Mh] Termos MeSH primário: Anti-Inflamatórios/química
Antineoplásicos Fitogênicos/química
PPAR alfa/agonistas
PPAR gama/agonistas
Senécio/química
Sesquiterpenos/química
[Mh] Termos MeSH secundário: Animais
Anti-Inflamatórios/isolamento & purificação
Anti-Inflamatórios/farmacologia
Antineoplásicos Fitogênicos/isolamento & purificação
Antineoplásicos Fitogênicos/farmacologia
Linhagem Celular Tumoral
Cercopithecus aethiops
Células Hep G2
Seres Humanos
Espectroscopia de Ressonância Magnética
Camundongos
Células RAW 264.7
Arábia Saudita
Sesquiterpenos/isolamento & purificação
Sesquiterpenos/farmacologia
Espectrometria de Massas por Ionização por Electrospray
Células Vero
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Anti-Inflammatory Agents); 0 (Antineoplastic Agents, Phytogenic); 0 (PPAR alpha); 0 (PPAR gamma); 0 (Sesquiterpenes); 0 (presilphiperfolanol)
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171006
[Lr] Data última revisão:
171006
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170629
[St] Status:MEDLINE
[do] DOI:10.1002/cbdv.201700144


  2 / 507 MEDLINE  
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[PMID]:28529177
[Au] Autor:Macedo GE; Gomes KK; Rodrigues NR; Martins IK; Wallau GDL; Carvalho NR; Cruz LCD; Costa Silva DGD; Boligon AA; Franco JL; Posser T
[Ad] Endereço:Oxidative Stress and Cell Signaling Research Group, Universidade Federal do Pampa, Campus São Gabriel, 97300-000 São Gabriel, RS, Brazil.
[Ti] Título:Senecio brasiliensis impairs eclosion rate and induces apoptotic cell death in larvae of Drosophila melanogaster.
[So] Source:Comp Biochem Physiol C Toxicol Pharmacol;198:45-57, 2017 Aug.
[Is] ISSN:1532-0456
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Senecio brasilienis (Spreng) Less., is a species native from Brazil, popularly known as "Maria mole", and known to induce hepatotoxicity due to its high content of Pyrrolizidine alkaloids. Despite its toxicity, this plant is widely used in Brazilian folk medicine. Considering the antagonizing effects described for S. brasiliensis, we describe here molecular markers involved in the toxicity of hydroalcoholic extract from leaves of S. brasiliensis (HESB) in Drosophila melanogaster. Phytochemical analysis of HESB revealed the presence of phenolic acids and flavonoids. A significant antioxidant potential against ABTS and DPPH radical was found in parallel. Ingestion of extract did not alter the survival and locomotor activity of adult flies. However when ingested along the larval developmental phase, the eclosion rate of flies was interrupted at higher concentration of extract. To comprehend this phenomenon several analysis were conducted in larvae. HESB stimulated activity of antioxidant enzymes SOD and GST, and increased GSH/GSSG ratio and ROS production. Additionally, HESB caused a significant decrease of cell viability. The mRNA expression of Nrf2, TrxR, CAT, Drice and Dilp6 were also significantly up-regulated. HESB caused significant decrease on the phosphorylation of MAPKs and AKT. In parallel, PARP cleavage and caspases 3/7 activity were stimulated. In addition, glucose, glycogen and triglycerides levels were decreased. Taken together our study depicts a disruption in the eclosion of D. melanogaster possibly attributed to the inhibition of kinases implied in developmental process, energetic demand and induction of apoptotic cell death process.
[Mh] Termos MeSH primário: Drosophila melanogaster/citologia
Drosophila melanogaster/efeitos dos fármacos
Extratos Vegetais/toxicidade
Senécio/química
[Mh] Termos MeSH secundário: Animais
Antioxidantes/metabolismo
Antioxidantes/farmacologia
Apoptose/efeitos dos fármacos
Brasil
Drosophila melanogaster/crescimento & desenvolvimento
Metabolismo Energético/efeitos dos fármacos
Enzimas/metabolismo
Feminino
Flavonoides/análise
Flavonoides/química
Glutationa/metabolismo
Larva/efeitos dos fármacos
Estresse Oxidativo/efeitos dos fármacos
Fenóis/análise
Fenóis/química
Extratos Vegetais/química
Extratos Vegetais/farmacologia
Folhas de Planta/química
Testes de Toxicidade/métodos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Antioxidants); 0 (Enzymes); 0 (Flavonoids); 0 (Phenols); 0 (Plant Extracts); GAN16C9B8O (Glutathione)
[Em] Mês de entrada:1707
[Cu] Atualização por classe:170728
[Lr] Data última revisão:
170728
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170523
[St] Status:MEDLINE


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[PMID]:27620169
[Au] Autor:Kokalj M; Prikerznik M; Kreft S
[Ad] Endereço:Faculty of Pharmacy, University of Ljubljana, SI-1000, Ljubljana, Slovenia.
[Ti] Título:FTIR spectroscopy as a tool to detect contamination of rocket (Eruca sativa and Diplotaxis tenuifolia) salad with common groundsel (Senecio vulgaris) leaves.
[So] Source:J Sci Food Agric;97(7):2238-2244, 2017 May.
[Is] ISSN:1097-0010
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Rocket is a popular salad vegetable used all over the world and it has many health benefits. However, like with all plant material, there exists a danger of contamination with toxic substances. In the case of rocket, contamination with groundsel has occurred. Groundsel is a common weed in rocket crops, and it contains very toxic pyrrolizidine alkaloids. In our study infrared spectroscopy was used to distinguish groundsel samples from rocket leaves. Infrared spectroscopy is a very simple analytical technique; however, some specific conditions are more easily implemented in industrial environment than others. Some of these conditions and parameters of infrared spectroscopy were explored in detail. RESULTS: We tested for the influence of different parameters of attenuated total reflectance and transmission infrared method. Our results show that a 100 % correct classification can be obtained under conditions most suitable for industry: using fresh samples and parameters that enable fast spectral measurement. CONCLUSION: Infrared spectroscopy is a fast and easy-to-use method that has been shown to be able to differentiate between rocket and groundsel leaves. Therefore, it could be further studied for implementation in the safety control of rocket salads. © 2016 Society of Chemical Industry.
[Mh] Termos MeSH primário: Brassicaceae/química
Contaminação de Alimentos/análise
Senécio/química
Espectroscopia de Infravermelho com Transformada de Fourier/métodos
Verduras/química
[Mh] Termos MeSH secundário: Folhas de Planta/química
[Pt] Tipo de publicação:EVALUATION STUDIES; JOURNAL ARTICLE
[Em] Mês de entrada:1711
[Cu] Atualização por classe:171113
[Lr] Data última revisão:
171113
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160914
[St] Status:MEDLINE
[do] DOI:10.1002/jsfa.8034


  4 / 507 MEDLINE  
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[PMID]:27546067
[Au] Autor:Ruiz-Vásquez L; Olmeda AS; Zúñiga G; Villarroel L; Echeverri LF; González-Coloma A; Reina M
[Ad] Endereço:Instituto de Productos Naturales y Agrobiología (IPNA) (CSIC), ES-38206, La Laguna, Tenerife, Spain.
[Ti] Título:Insect Antifeedant and Ixodicidal Compounds from Senecio adenotrichius.
[So] Source:Chem Biodivers;14(1), 2017 Jan.
[Is] ISSN:1612-1880
[Cp] País de publicação:Switzerland
[La] Idioma:eng
[Ab] Resumo:Nine eremophilane sesquiterpenes 1 - 9, two flavonoids 11 and 12, and two known pirrolizidine alkaloids 13 and 14, were isolated from Senecio adenotrichius DC. Their structures were elucidated on the basis of spectroscopic data and by comparison with previously reported spectroscopic data of similar compounds. Compounds 5, 7, and 9 have not been previously reported as natural products. The antifeedant activity of these compounds was tested against Spodoptera litoralis and Myzus persicae. Eremophilanes 1, 3, and 8 were strong antifeedants to M. persicae, and 1 and 8 to Spodoptera littoralis. Their ixodicidal activity was tested against the tick Hyalomma lusitanicum, with eremophilanes 1, 3, and 8, being strong ixodicidal agents.
[Mh] Termos MeSH primário: Inseticidas/química
Senécio/química
[Mh] Termos MeSH secundário: Alcaloides/isolamento & purificação
Alcaloides/farmacologia
Animais
Afídeos/efeitos dos fármacos
Flavonoides/isolamento & purificação
Flavonoides/farmacologia
Inseticidas/isolamento & purificação
Inseticidas/farmacologia
Extratos Vegetais/química
Sesquiterpenos/isolamento & purificação
Sesquiterpenos/farmacologia
Spodoptera/efeitos dos fármacos
Relação Estrutura-Atividade
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Alkaloids); 0 (Flavonoids); 0 (Insecticides); 0 (Plant Extracts); 0 (Sesquiterpenes)
[Em] Mês de entrada:1701
[Cu] Atualização por classe:170127
[Lr] Data última revisão:
170127
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160823
[St] Status:MEDLINE
[do] DOI:10.1002/cbdv.201600155


  5 / 507 MEDLINE  
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[PMID]:27787899
[Au] Autor:Emanuelli MP; Antoniazzi AQ; Cecim MS; Fighera RA
[Ad] Endereço:Department of Small Animal Clinical Sciences, Federal University of Santa Maria, Santa Maria, Brazil.
[Ti] Título:What is your diagnosis? Liver from a cow.
[So] Source:Vet Clin Pathol;45(4):721-722, 2016 Dec.
[Is] ISSN:1939-165X
[Cp] País de publicação:United States
[La] Idioma:eng
[Mh] Termos MeSH primário: Doenças dos Bovinos/diagnóstico
Hepatopatias/veterinária
Intoxicação por Plantas/veterinária
Alcaloides de Pirrolizidina/envenenamento
Senécio/envenenamento
[Mh] Termos MeSH secundário: Animais
Biópsia por Agulha Fina/veterinária
Bovinos
Doenças dos Bovinos/etiologia
Doenças dos Bovinos/patologia
Feminino
Fígado/patologia
Hepatopatias/diagnóstico
Hepatopatias/etiologia
Hepatopatias/patologia
Intoxicação por Plantas/diagnóstico
Intoxicação por Plantas/etiologia
Intoxicação por Plantas/patologia
Senécio/química
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Pyrrolizidine Alkaloids)
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170809
[Lr] Data última revisão:
170809
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161028
[St] Status:MEDLINE
[do] DOI:10.1111/vcp.12414


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[PMID]:27555436
[Au] Autor:Kandziora M; Kadereit JW; Gehrke B
[Ad] Endereço:Institut für Spezielle Botanik und Botanischer Garten, Johannes Gutenberg-Universität, Mainz, Germany martha.kandziora@yahoo.com.
[Ti] Título:Frequent colonization and little in situ speciation in Senecio in the tropical alpine-like islands of eastern Africa.
[So] Source:Am J Bot;103(8):1483-98, 2016 08.
[Is] ISSN:1537-2197
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:PREMISE OF THE STUDY: Floras of continental habitat islands, like those of islands, originate mostly through colonization, which can be followed by in situ speciation. We here address the question of the relative importance of colonization and in situ diversification in the high-altitude areas of the eastern African high mountains, the tropical Afroalpine Region, using the most species-rich genus in the region, Senecio, as an example. METHODS: We expanded earlier Senecioneae phylogenies by adding more tropical African species and analyzed our phylogenetic tree biogeographically. KEY RESULTS: Senecio contains at least five clades with tropical African species, all of them containing tropical afroalpine species. Between four to 14 independent colonization events into the tropical Afroalpine most likely from montane regions in southern Africa were found. Additionally, relationships of tropical afroalpine species to Palearctic and South American taxa were identified. Although some in situ diversification occurred in Senecio in the tropical Afroalpine, the resulting number of species per clade is never higher than seven. CONCLUSION: Like other genera, Senecio colonized the tropical Afroalpine several times independently. Comparison with Mt. Kinabalu, a small tropical alpine-like region in Southeast Asia, and alpine-like regions in the Andes implies that rates of in situ speciation might be linked to area size.
[Mh] Termos MeSH primário: Especiação Genética
Filogenia
Senécio/genética
[Mh] Termos MeSH secundário: África Oriental
DNA de Plantas/genética
Filogeografia
Senécio/classificação
Análise de Sequência de DNA
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (DNA, Plant)
[Em] Mês de entrada:1709
[Cu] Atualização por classe:171121
[Lr] Data última revisão:
171121
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160825
[St] Status:MEDLINE
[do] DOI:10.3732/ajb.1600210


  7 / 507 MEDLINE  
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[PMID]:27498832
[Au] Autor:Singh R; Ahluwalia V; Singh P; Kumar N; Prakash Sati O; Sati N
[Ad] Endereço:a Department of Chemistry , HNB Garhwal University (A Central University) , Srinagar , India.
[Ti] Título:Antifungal and phytotoxic activity of essential oil from root of Senecio amplexicaulis Kunth. (Asteraceae) growing wild in high altitude-Himalayan region.
[So] Source:Nat Prod Res;30(16):1875-9, 2016 Aug.
[Is] ISSN:1478-6427
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:This work was aimed to evaluate the essential oil from root of medicinally important plant Senecio amplexicaulis for chemical composition, antifungal and phytotoxic activity. The chemical composition analysed by GC/GC-MS showed the presence of monoterpene hydrocarbons in high percentage with marker compounds as α-phellandrene (48.57%), o-cymene (16.80%) and ß-ocimene (7.61%). The essential oil exhibited significant antifungal activity against five phytopathogenic fungi, Sclerotium rolfsii, Macrophomina phaseolina, Rhizoctonia solani, Pythium debaryanum and Fusarium oxysporum. The oil demonstrated remarkable phytotoxic activity in tested concentration and significant reduction in seed germination percentage of Phalaris minor and Triticum aestivum at higher concentrations. The roots essential oil showed high yield for one of its marker compound (α-phellandrene) which makes it important natural source of this compound.
[Mh] Termos MeSH primário: Antifúngicos/farmacologia
Óleos Voláteis/química
Óleos Voláteis/farmacologia
Senécio/química
[Mh] Termos MeSH secundário: Alcenos/análise
Altitude
Antifúngicos/química
Ascomicetos/efeitos dos fármacos
Ascomicetos/patogenicidade
Fusarium/efeitos dos fármacos
Fusarium/patogenicidade
Cromatografia Gasosa-Espectrometria de Massas
Germinação/efeitos dos fármacos
Índia
Monoterpenos/análise
Phalaris/efeitos dos fármacos
Phalaris/crescimento & desenvolvimento
Raízes de Plantas/química
Rhizoctonia/efeitos dos fármacos
Rhizoctonia/patogenicidade
Sementes/efeitos dos fármacos
Sementes/crescimento & desenvolvimento
Triticum/efeitos dos fármacos
Triticum/crescimento & desenvolvimento
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Alkenes); 0 (Antifungal Agents); 0 (Monoterpenes); 0 (Oils, Volatile); 13877-91-3 (beta-ocimene); 49JV13XE39 (alpha phellandrene)
[Em] Mês de entrada:1705
[Cu] Atualização por classe:170817
[Lr] Data última revisão:
170817
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160809
[St] Status:MEDLINE
[do] DOI:10.1080/14786419.2015.1079910


  8 / 507 MEDLINE  
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[PMID]:27467750
[Au] Autor:Bühler M; Bogenrieder A; Sandermann H; Ernst D
[Ti] Título:Heteroplasmy and atrazine resistance in Chenopodium album and Senecio vulgaris.
[So] Source:Z Naturforsch C;71(7-8):267-72, 2016.
[Is] ISSN:0939-5075
[Cp] País de publicação:Germany
[La] Idioma:eng
[Ab] Resumo:Atrazine-resistant weeds are well known, and the resistance is primarily caused by a point mutation in the psbA chloroplast gene encoding the photosystem II D1 protein. Heteroplasmy, the presence of different types of chloroplasts in an individual plant, is also very common. Thus, atrazine-resistant weeds may also partly possess the atrazine-binding sequence and vice versa. The region of the psbA gene containing the mutation was sequenced from atrazine-resistant and atrazine-sensitive Chenopodium album and Senecio vulgaris plants. In atrazine-sensitive C. album plants, the expected AGT triplet was found. The atrazine-resistant plants contained the expected base substitution (AGT to GGT); however, in addition the AGT triplet was found. The atrazine-resistant S. vulgaris plants contained the expected GGT sequence, whereas the atrazine-sensitive plants contained both the AGT and GGT sequences. This clearly indicates that in addition to Gly264 also Ser264 is present in atrazine-resistant plants, and vice versa in atrazine-sensitive plants, indicating heteroplasmy in these weeds.
[Mh] Termos MeSH primário: Atrazina/farmacologia
Chenopodium album/genética
DNA de Cloroplastos/genética
Resistência a Medicamentos/genética
Variação Genética
Senécio/genética
[Mh] Termos MeSH secundário: Substituição de Aminoácidos
Sequência de Bases
DNA de Cloroplastos/química
Glicina/genética
Herbicidas/farmacologia
Complexo de Proteína do Fotossistema II/genética
Mutação Puntual
Análise de Sequência de DNA
Serina/genética
Especificidade da Espécie
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (DNA, Chloroplast); 0 (Herbicides); 0 (Photosystem II Protein Complex); 452VLY9402 (Serine); QJA9M5H4IM (Atrazine); TE7660XO1C (Glycine)
[Em] Mês de entrada:1701
[Cu] Atualização por classe:170113
[Lr] Data última revisão:
170113
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160729
[St] Status:MEDLINE


  9 / 507 MEDLINE  
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[PMID]:27451168
[Au] Autor:Nowak M; Wittke C; Lederer I; Klier B; Kleinwächter M; Selmar D
[Ad] Endereço:Institut für Pflanzenbiologie, Technische Universität Braunschweig, Mendelssohnstraße 4, D-38106 Braunschweig, Germany. Electronic address: m.nowak@tu-bs.de.
[Ti] Título:Interspecific transfer of pyrrolizidine alkaloids: An unconsidered source of contaminations of phytopharmaceuticals and plant derived commodities.
[So] Source:Food Chem;213:163-168, 2016 Dec 15.
[Is] ISSN:0308-8146
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Many plant derived commodities contain traces of toxic pyrrolizidine alkaloids (PAs). The main source of these contaminations seems to be the accidental co-harvest of PA-containing weeds. Yet, based on the insights of the newly described phenomenon of the horizontal transfer of natural products, it is very likely that the PA-contaminations may also be due to an uptake of the alkaloids from the soil, previously being leached out from rotting PA-plants. The transfer of PAs was investigated using various herbs, which had been mulched with dried plant material from Senecio jacobaea. All of the acceptor plants exhibited marked concentrations of PAs. The extent and the composition of the imported PAs was dependent on the acceptor plant species. These results demonstrate that PAs indeed are leached out from dried Senecio material into the soil and confirm their uptake by the roots of the acceptor plants and the translocation into the leaves.
[Mh] Termos MeSH primário: Contaminação de Medicamentos
Compostos Fitoquímicos/análise
Plantas Daninhas/química
Alcaloides de Pirrolizidina/análise
Poluentes do Solo/análise
[Mh] Termos MeSH secundário: Folhas de Planta/química
Raízes de Plantas/química
Senécio/química
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Phytochemicals); 0 (Pyrrolizidine Alkaloids); 0 (Soil Pollutants)
[Em] Mês de entrada:1701
[Cu] Atualização por classe:170809
[Lr] Data última revisão:
170809
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160725
[St] Status:MEDLINE


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[PMID]:27436057
[Au] Autor:Walter GM; Wilkinson MJ; James ME; Richards TJ; Aguirre JD; Ortiz-Barrientos D
[Ad] Endereço:School of Biological Sciences, University of Queensland, St. Lucia QLD 4072, Australia. gregory.walter@uqconnect.edu.au.
[Ti] Título:Diversification across a heterogeneous landscape.
[So] Source:Evolution;70(9):1979-92, 2016 Sep.
[Is] ISSN:1558-5646
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Adaptation to contrasting environments across a heterogeneous landscape favors the formation of ecotypes by promoting ecological divergence. Patterns of fitness variation in the field can show whether natural selection drives local adaptation and ecotype formation. However, to demonstrate a link between ecological divergence and speciation, local adaptation must have consequences for reproductive isolation. Using contrasting ecotypes of an Australian wildflower, Senecio lautus in common garden experiments, hybridization experiments, and reciprocal transplants, we assessed how the environment shapes patterns of adaptation and the consequences of adaptive divergence for reproductive isolation. Local adaptation was strong between ecotypes, but weaker between populations of the same ecotype. F1 hybrids exhibited heterosis, but crosses involving one native parent performed better than those with two foreign parents. In a common garden experiment, F2 hybrids exhibited reduced fitness compared to parentals and F1 hybrids, suggesting that few genetic incompatibilities have accumulated between populations adapted to contrasting environments. Our results show how ecological differences across the landscape have created complex patterns of local adaptation and reproductive isolation, suggesting that divergent natural selection has played a fundamental role in the early stages of species diversification.
[Mh] Termos MeSH primário: Ecótipo
Hibridização Genética
Senécio/genética
[Mh] Termos MeSH secundário: Adaptação Biológica
Austrália
Especiação Genética
Isolamento Reprodutivo
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170922
[Lr] Data última revisão:
170922
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160721
[St] Status:MEDLINE
[do] DOI:10.1111/evo.13009



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