Base de dados : MEDLINE
Pesquisa : B01.650.940.800.575.912.250.100.843 [Categoria DeCS]
Referências encontradas : 287 [refinar]
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[PMID]:29258552
[Au] Autor:Chavushyan VA; Simonyan KV; Simonyan RM; Isoyan AS; Simonyan GM; Babakhanyan MA; Hovhannisyian LE; Nahapetyan KH; Avetisyan LG; Simonyan MA
[Ad] Endereço:Orbeli Institute of Physiology NAS RA, 22 Orbeli Bros Street, 0028, Yerevan, Armenia.
[Ti] Título:Effects of stevia on synaptic plasticity and NADPH oxidase level of CNS in conditions of metabolic disorders caused by fructose.
[So] Source:BMC Complement Altern Med;17(1):540, 2017 Dec 19.
[Is] ISSN:1472-6882
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Excess dietary fructose intake associated with metabolic syndrome and insulin resistance and increased risk of developing type 2 diabetes. Previous animal studies have reported that diabetic animals have significantly impaired behavioural and cognitive functions, pathological synaptic function and impaired expression of glutamate receptors. Correction of the antioxidant status of laboratory rodents largely prevents the development of fructose-induced plurimetabolic changes in the nervous system. We suggest a novel concept of efficiency of Stevia leaves for treatment of central diabetic neuropathy. METHODS: By in vivo extracellular studies induced spike activity of hippocampal neurons during high frequency stimulation of entorhinal cortex, as well as neurons of basolateral amygdala to high-frequency stimulation of the hippocampus effects of Stevia rebaudiana Bertoni plant evaluated in synaptic activity in the brain of fructose-enriched diet rats. In the conditions of metabolic disorders caused by fructose, antioxidant activity of Stevia rebaudiana was assessed by measuring the NOX activity of the hippocampus, amygdala and spinal cord. RESULTS: In this study, the characteristic features of the metabolic effects of dietary fructose on synaptic plasticity in hippocampal neurons and basolateral amygdala and the state of the NADPH oxidase (NOX) oxidative system of these brain formations are revealed, as well as the prospects for development of multitarget and polyfunctional phytopreparations (with adaptogenic, antioxidant, antidiabetic, nootropic activity) from native raw material of Stevia rebaudiana. Stevia modulates degree of expressiveness of potentiation/depression (approaches but fails to achieve the norm) by shifting the percentage balance in favor of depressor type of responses during high-frequency stimulation, indicating its adaptogenic role in plasticity of neural networks. Under the action of fructose an increase (3-5 times) in specific quantity of total fraction of NOX isoforms isolated from the central nervous system tissue (amygdala, hippocampus, spinal cord) was revealed. Stevia exhibits an antistress, membrane-stabilizing role reducing the level of total fractions of NOX isoforms from central nervous system tissues and regulates NADPH-dependent O -producing activity. CONCLUSION: Generally, in condition of metabolic disorders caused by intensive consumption of dietary fructose Stevia leaves contributes to the control of neuronal synaptic plasticity possibly influencing the conjugated NOX-specific targets.
[Mh] Termos MeSH primário: Química Encefálica/efeitos dos fármacos
Encéfalo/efeitos dos fármacos
Diterpenos Caurânicos/farmacologia
Frutose/efeitos adversos
Glucosídeos/farmacologia
NADPH Oxidases/análise
Plasticidade Neuronal/efeitos dos fármacos
[Mh] Termos MeSH secundário: Potenciais de Ação/efeitos dos fármacos
Animais
Encéfalo/citologia
Encéfalo/enzimologia
Açúcares da Dieta/efeitos adversos
Masculino
Doenças Metabólicas/induzido quimicamente
Doenças Metabólicas/metabolismo
NADPH Oxidases/metabolismo
Ratos
Stevia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Dietary Sugars); 0 (Diterpenes, Kaurane); 0 (Glucosides); 0YON5MXJ9P (stevioside); 30237-26-4 (Fructose); EC 1.6.3.- (NADPH Oxidases)
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180108
[Lr] Data última revisão:
180108
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171221
[St] Status:MEDLINE
[do] DOI:10.1186/s12906-017-2049-9


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[PMID]:28552425
[Au] Autor:Wald JP; Morlock GE
[Ad] Endereço:Chair of Food Sciences, Institute for Nutritional Science and Interdisciplinary Research Center (IFZ), Justus Liebig University Giessen, Heinrich-Buff-Ring 26-32, 35392 Giessen, Germany.
[Ti] Título:Quantification of steviol glycosides in food products, Stevia leaves and formulations by planar chromatography, including proof of absence for steviol and isosteviol.
[So] Source:J Chromatogr A;1506:109-119, 2017 Jul 14.
[Is] ISSN:1873-3778
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:Steviol glycosides may degrade in food products under certain processing and storage conditions. Hence, a method was developed that separated in the same chromatographic run seven important steviol glycosides, and additionally as a sum parameter, their reported breakdown products steviol and isosteviol. Through derivatizations with the 2-naphthol and the primuline reagent, the detection was selective and inexpensive. In case needed, the baseline separation of steviol and isosteviol was also demonstrated after a plate cut and subsequent short development (two-step method). The HPTLC method was robust with regard to varying sample matrix loads, as the stationary phase was used only once. A high sample throughput was achieved, i.e. 23 separations were performed in parallel on one plate. The total analysis time took 1h (30min application, 15min separation and 15min derivatization/densitometry) leading to a calculated analysis time of 2.6min per sample. The solvent consumption was 8mL in total (0.4mL per analysis). HPTLC-ESI-MS was employed for confirmation of the results obtained. Mass spectra were recorded only from the zones of interest, and not from matrix or background, leading to decisive advantages, such as less need for MS cleaning. The optimized HPTLC method was shown to effectively support quality control, as marketed samples may be falsified with cheaper synthetic sweeteners, which was also demonstrated in this study. The accuracy of the densitometric quantification in HPTLC was considered as high, as standards and samples were separated on fresh adsorbent and detected simultaneously under identical conditions, which minimized the influence of errors. Finally, the Aliivibrio fischeri bioassay was employed to obtain information on bioactive compounds in Stevia leaf extracts.
[Mh] Termos MeSH primário: Cromatografia Líquida de Alta Pressão/métodos
Diterpenos Caurânicos/análise
Glicosídeos/análise
Extratos Vegetais/análise
Stevia/química
Edulcorantes/análise
[Mh] Termos MeSH secundário: Análise de Alimentos
Espectrometria de Massas/métodos
Folhas de Planta/química
[Pt] Tipo de publicação:EVALUATION STUDIES; JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Diterpenes, Kaurane); 0 (Glycosides); 0 (Plant Extracts); 0 (Sweetening Agents); 091QB7QO95 (isosteviol); 4741LYX6RT (steviol)
[Em] Mês de entrada:1711
[Cu] Atualização por classe:171102
[Lr] Data última revisão:
171102
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170530
[St] Status:MEDLINE


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[PMID]:28490088
[Au] Autor:Yu H; Yang G; Sato M; Yamaguchi T; Nakano T; Xi Y
[Ad] Endereço:College of Food Engineering, Ludong University, Yantai 264025, PR China; Graduate School of Agricultural Science, Tohoku University, Sendai 981-8555, Japan. Electronic address: zoehuihui@hotmail.com.
[Ti] Título:Antioxidant activities of aqueous extract from Stevia rebaudiana stem waste to inhibit fish oil oxidation and identification of its phenolic compounds.
[So] Source:Food Chem;232:379-386, 2017 Oct 01.
[Is] ISSN:0308-8146
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:We investigated the potential for exploiting Stevia rebaudiana stem (SRS) waste as a source of edible plant-based antioxidants finding for the first time that the hot water extract of SRS had significantly higher antioxidant activity against fish oil oxidation than that of the leaf, despite SRS extract having lower total phenolic content, DPPH radical scavenging activity and ORAC values. To locate the major antioxidant ingredients, SRS extract was fractionated using liquid chromatography. Five phenolic compounds (primary antioxidant components in activity-containing fractions) were identified by NMR and HR-ESI-MS: vanillic acid 4-O-ß-d-glucopyranoside (1), protocatechuic acid (2), caffeic acid (3), chlorogenic acid (4) and cryptochlorogenic acid (5). Further analysis showed that, among compounds 2-5, protocatechuic acid had the highest capacity to inhibit peroxides formation, but exhibited the lowest antioxidant activities in DPPH and ORAC assays. These results indicate that SRS waste can be used as strong natural antioxidant materials in the food industry.
[Mh] Termos MeSH primário: Óleos de Peixe/química
Stevia/química
[Mh] Termos MeSH secundário: Antioxidantes
Fenóis
Extratos Vegetais
Caules de Planta
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Antioxidants); 0 (Fish Oils); 0 (Phenols); 0 (Plant Extracts)
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170901
[Lr] Data última revisão:
170901
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170512
[St] Status:MEDLINE


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[PMID]:28372164
[Au] Autor:Ameer K; Bae SW; Jo Y; Lee HG; Ameer A; Kwon JH
[Ad] Endereço:School of Food Science & Biotechnology, Kyungpook National University, Daegu 41566 Republic of Korea.
[Ti] Título:Optimization of microwave-assisted extraction of total extract, stevioside and rebaudioside-A from Stevia rebaudiana (Bertoni) leaves, using response surface methodology (RSM) and artificial neural network (ANN) modelling.
[So] Source:Food Chem;229:198-207, 2017 Aug 15.
[Is] ISSN:0308-8146
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Stevia rebaudiana (Bertoni) consists of stevioside and rebaudioside-A (Reb-A). We compared response surface methodology (RSM) and artificial neural network (ANN) modelling for their estimation and predictive capabilities in building effective models with maximum responses. A 5-level 3-factor central composite design was used to optimize microwave-assisted extraction (MAE) to obtain maximum yield of target responses as a function of extraction time (X : 1-5min), ethanol concentration, (X : 0-100%) and microwave power (X : 40-200W). Maximum values of the three output parameters: 7.67% total extract yield, 19.58mg/g stevioside yield, and 15.3mg/g Reb-A yield, were obtained under optimum extraction conditions of 4min X , 75% X , and 160W X . The ANN model demonstrated higher efficiency than did the RSM model. Hence, RSM can demonstrate interaction effects of inherent MAE parameters on target responses, whereas ANN can reliably model the MAE process with better predictive and estimation capabilities.
[Mh] Termos MeSH primário: Diterpenos Caurânicos/química
Glucosídeos/química
Glicosídeos/química
Folhas de Planta/química
Stevia/química
[Mh] Termos MeSH secundário: Micro-Ondas
Redes Neurais (Computação)
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Diterpenes, Kaurane); 0 (Glucosides); 0 (Glycosides); 0YON5MXJ9P (stevioside)
[Em] Mês de entrada:1705
[Cu] Atualização por classe:170505
[Lr] Data última revisão:
170505
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170405
[St] Status:MEDLINE


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[PMID]:28364791
[Au] Autor:Akbari F; Arminian A; Kahrizi D; Fazeli A
[Ad] Endereço:Department of Agronomy and Plant Breeding, Faculty of Agriculture, Ilam University, Ilam, Iran.
[Ti] Título:Effect of nitrogen sources on some morphological characteristics of in vitro stevia rebaudiana Bertoni.
[So] Source:Cell Mol Biol (Noisy-le-grand);63(2):107-111, 2017 Feb 28.
[Is] ISSN:1165-158X
[Cp] País de publicação:France
[La] Idioma:eng
[Ab] Resumo:Stevia rebaudiana Bertoni belongs to Asteraceae family that leaves 200-300 times sweeter than sugar. Low seed fertility is one of the most important problems in Stevia production. So, Plant tissue culture is an efficient method for mass propagation of Stevia. In this research, we studied the effect of various concentrations of nitrogen on some morphological traits of stevia under in vitro conditions. We used axillary nodes as explants and they were cultured on Murashige and Skoog (MS) medium containing inorganic nitrogen sources i.e. NH4NO3(0, 825 and 1650 mg/l), KNO3(0, 950 and 1900 mg/l) were observed. The cultures were kept for 4 weeks at a temperature of 25±2°C with a photoperiod of 16/8 hour low light/dark each day. Maximum shoot length (89.33 mm), dry weight of plants (0.10 mg) and leaf fresh weight (0.42 mg) was observed on MS medium with 1650 mg/l NH4NO3 and 950 mg/l KNO3. Minimum shoot length (6.13 mm), root length (6.60 mm), leaf number (4.26), leaf dry weight (0.01 mg), leaf fresh weight (0.05 mg), total dry and fresh weight (0.02 and 0.15 mg) and growth rate was observed on a MS medium without nitrogen sources. Moreover, presence of nitrogen sources increases both shooting and rooting in Stevia rebaudiana Bertoni.
[Mh] Termos MeSH primário: Nitratos/farmacologia
Compostos de Potássio/farmacologia
Stevia/efeitos dos fármacos
Técnicas de Cultura de Tecidos/métodos
[Mh] Termos MeSH secundário: Biomassa
Relação Dose-Resposta a Droga
Folhas de Planta/efeitos dos fármacos
Folhas de Planta/crescimento & desenvolvimento
Raízes de Plantas/efeitos dos fármacos
Raízes de Plantas/crescimento & desenvolvimento
Brotos de Planta/efeitos dos fármacos
Brotos de Planta/crescimento & desenvolvimento
Stevia/crescimento & desenvolvimento
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Nitrates); 0 (Potassium Compounds); RU45X2JN0Z (potassium nitrate); T8YA51M7Y6 (ammonium nitrate)
[Em] Mês de entrada:1704
[Cu] Atualização por classe:170426
[Lr] Data última revisão:
170426
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170403
[St] Status:MEDLINE
[do] DOI:10.14715/cmb/2017.63.2.17


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[PMID]:28358484
[Au] Autor:Chacón Morales PA; Amaro-Luis JM; Kutateladze AG
[Ad] Endereço:Laboratory of Natural Products, Department of Chemistry, Faculty of Sciences, University of "Los Andes" , Mérida 5101, Venezuela.
[Ti] Título:Structure Determination and Mechanism of Formation of a seco-Moreliane Derivative Supported by Computational Analysis.
[So] Source:J Nat Prod;80(4):1210-1214, 2017 Apr 28.
[Is] ISSN:1520-6025
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Basic hydrolysis of a dichloromethane extract of Stevia lucida yielded (4R,5S,7R,9R,10R,11R)-7,9-dihydroxylongipin-2-en-1-one (1), which was oxidized and subjected to acidic conditions to generate the new seco-moreliane derivative 3. The structure of 3 was established based on NMR data interpretation and confirmed computationally. A plausible mechanism for the carbocationic rearrangement of the trione 2 to the seco-moreliane 3 was supported by DFT computations.
[Mh] Termos MeSH primário: Sesquiterpenos/isolamento & purificação
Stevia/química
[Mh] Termos MeSH secundário: Hidrólise
Modelos Moleculares
Conformação Molecular
Estrutura Molecular
Ressonância Magnética Nuclear Biomolecular
Oxirredução
Sesquiterpenos/química
Estereoisomerismo
Venezuela
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Sesquiterpenes)
[Em] Mês de entrada:1707
[Cu] Atualização por classe:170726
[Lr] Data última revisão:
170726
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170331
[St] Status:MEDLINE
[do] DOI:10.1021/acs.jnatprod.7b00041


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[PMID]:28346877
[Au] Autor:Sansano S; Rivas A; Pina-Pérez MC; Martinez A; Rodrigo D
[Ad] Endereço:Universidad CEU Cardenal Herrera, Dpto. Producción y Sanidad Animal, Salud Pública Veterinaria y Ciencia y Tecnología de los Alimentos, C/ Tirant lo Blanc, 7, 46115 Alfara del Patriarca, Valencia, Spain.
[Ti] Título:Stevia rebaudiana Bertoni effect on the hemolytic potential of Listeria monocytogenes.
[So] Source:Int J Food Microbiol;250:7-11, 2017 Jun 05.
[Is] ISSN:1879-3460
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:The effect of Stevia rebaudiana Bertoni on the hemolytic potential of Listeria monocytogenes was studied by means of the assessment of the Listeriolysin O (LLO) production. The three factors under study, stevia concentration in the range [0-2.5] % (w/v), incubation temperature (10 and 37°C), and exposure time (0-65h) significantly affected (p≤0.05) the hemolytic activity of L. monocytogenes. Results showed that at the lower incubation temperature the hemolytic potential of the bacterium was significantly reduced, from 100% at 37°C to 8% at 10°C (after 65h of incubation) in unsupplemented substrate (0% stevia). Irrespective of the temperature, 10 or 37°C, supplementation of the medium with stevia at 2.5 % (w/v) reduced the bacterium's hemolytic activity by a maximum of 100%. Furthermore, the time of exposure to 2.5 % (w/v) stevia concentration was also a significant factor reducing the hemolytic capability of L. monocytogenes. The possibility of reducing the pathogenic potential of L. monocytogenes (hemolysis) by exposure to stevia should be confirmed in real food matrices, opening a research niche with a valuable future impact on food safety.
[Mh] Termos MeSH primário: Toxinas Bacterianas/biossíntese
Citotoxinas/biossíntese
Diterpenos Caurânicos/farmacologia
Glucosídeos/farmacologia
Proteínas de Choque Térmico/biossíntese
Proteínas Hemolisinas/biossíntese
Listeria monocytogenes/patogenicidade
Extratos Vegetais/farmacologia
[Mh] Termos MeSH secundário: Listeria monocytogenes/efeitos dos fármacos
Stevia/metabolismo
Temperatura Ambiente
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Bacterial Toxins); 0 (Cytotoxins); 0 (Diterpenes, Kaurane); 0 (Glucosides); 0 (Heat-Shock Proteins); 0 (Hemolysin Proteins); 0 (Plant Extracts); 0YON5MXJ9P (stevioside); 72270-41-8 (hlyA protein, Listeria monocytogenes)
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170928
[Lr] Data última revisão:
170928
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170328
[St] Status:MEDLINE


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[PMID]:28343388
[Au] Autor:Udompaisarn S; Arthan D; Somana J
[Ad] Endereço:Department of Biochemistry, Faculty of Science, Mahidol University , Rama 6 Road, Bangkok 10400, Thailand.
[Ti] Título:Development and Validation of an Enzymatic Method To Determine Stevioside Content from Stevia rebaudiana.
[So] Source:J Agric Food Chem;65(15):3223-3229, 2017 Apr 19.
[Is] ISSN:1520-5118
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:An enzymatic method for specific determination of stevioside content was established. Recombinant ß-glucosidase BT_3567 (rBT_3567) from Bacteroides thetaiotaomicron HB-13 exhibited selective hydrolysis of stevioside at ß-1,2-glycosidic bond to yield rubusoside and glucose. Coupling of this enzyme with glucose oxidase and peroxidase allowed for quantitation of stevioside content in Stevia samples by using a colorimetric-based approach. The series of reactions for stevioside determination can be completed within 1 h at 37 °C. Stevioside determination using the enzymatic assay strongly correlated with results obtained from HPLC quantitation (r = 0.9629, n = 16). The percentages of coefficient variation (CV) of within day (n = 12) and between days (n = 12) assays were lower than 5%, and accuracy ranges were 95-105%. This analysis demonstrates that the enzymatic method developed in this study is specific, easy to perform, accurate, and yields reproducible results.
[Mh] Termos MeSH primário: Proteínas de Bactérias/química
Bacteroides thetaiotaomicron/enzimologia
Ensaios Enzimáticos/métodos
Extratos Vegetais/análise
Stevia/química
Edulcorantes/análise
beta-Glucosidase/química
[Mh] Termos MeSH secundário: Biocatálise
Colorimetria/métodos
Diterpenos Caurânicos/análise
Glucose Oxidase/química
Glucosídeos/análise
[Pt] Tipo de publicação:EVALUATION STUDIES; JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Bacterial Proteins); 0 (Diterpenes, Kaurane); 0 (Glucosides); 0 (Plant Extracts); 0 (Sweetening Agents); 0YON5MXJ9P (stevioside); EC 1.1.3.4 (Glucose Oxidase); EC 3.2.1.21 (beta-Glucosidase)
[Em] Mês de entrada:1706
[Cu] Atualização por classe:170601
[Lr] Data última revisão:
170601
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170328
[St] Status:MEDLINE
[do] DOI:10.1021/acs.jafc.6b05793


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[PMID]:28334357
[Au] Autor:Dess NK; Dobson K; Roberts BT; Chapman CD
[Ad] Endereço:Department of Psychology, Occidental College, 1600 Campus Road, Los Angeles, CA 90041, USA.
[Ti] Título:Sweetener Intake by Rats Selectively Bred for Differential Saccharin Intake: Sucralose, Stevia, and Acesulfame Potassium.
[So] Source:Chem Senses;42(5):381-392, 2017 Jun 01.
[Is] ISSN:1464-3553
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Behavioral responses to sweeteners have been used to study the evolution, mechanisms, and functions of taste. Occidental low and high saccharin consuming rats (respectively, LoS and HiS) have been selectively outbred on the basis of saccharin intake and are a valuable tool for studying variation among individuals in sweetener intake and its correlates. Relative to HiS rats, LoS rats consume smaller amounts of all nutritive and nonnutritive sweeteners tested to date, except aspartame. The lines also differ in intake of the commercial product Splenda; the roles of sucralose and saccharides in the difference are unclear. The present study extends prior work by examining intake of custom mixtures of sucralose, maltodextrin, and sugars and Splenda by LoS and HiS rats (Experiment 1A-1D), stevia and a constituent compound (rebaudioside A; Experiment 2A-2E), and acesulfame potassium tested at several concentrations or with 4 other sweeteners at one concentration each (Experiment 3A-3B). Results indicate that aversive side tastes limit intake of Splenda, stevia, and acesulfame potassium, more so among LoS rats than among HiS rats. In addition, regression analyses involving 5 sweeteners support the idea that both sweetness and bitterness are needed to account for intake of nonnutritive sweeteners, more so among LoS rats. These findings contribute to well developed and emerging literatures on sweetness and domain-general processes related to gustation.
[Mh] Termos MeSH primário: Ingestão de Alimentos
Sacarina/administração & dosagem
Stevia/química
Sacarose/análogos & derivados
Edulcorantes/administração & dosagem
Paladar/efeitos dos fármacos
Paladar/genética
Tiazinas/administração & dosagem
[Mh] Termos MeSH secundário: Animais
Ratos
Análise de Regressão
Sacarina/farmacologia
Sacarose/administração & dosagem
Sacarose/farmacologia
Edulcorantes/farmacologia
Paladar/fisiologia
Tiazinas/farmacologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Sweetening Agents); 0 (Thiazines); 57-50-1 (Sucrose); 96K6UQ3ZD4 (trichlorosucrose); FST467XS7D (Saccharin); MA3UYZ6K1H (acetosulfame)
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170913
[Lr] Data última revisão:
170913
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170324
[St] Status:MEDLINE
[do] DOI:10.1093/chemse/bjx017


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[PMID]:28278673
[Au] Autor:Kilam D; Saifi M; Agnihotri A; Abdin MZ
[Ad] Endereço:a Amity Institute of Microbial Technology , Amity University , Noida , India.
[Ti] Título:Development of an efficient high-performance thin layer chromatography method for determination of jasmonic acid in leaf tissue of Stevia rebaudiana (Bertoni) Bertoni.
[So] Source:Nat Prod Res;31(14):1713-1716, 2017 Jul.
[Is] ISSN:1478-6427
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Determination of endogenous levels of jasmonic acid (JA) is essential, as it plays a pivotal role in the physiological processes during a plant's life cycle. A high performance thin layer chromatography (HPTLC) method was developed for the detection and quantification of JA in leaf extracts of medicinal plant, Stevia rebaudiana (Bertoni) Bertoni. The separation was achieved using the solvents ethyl acetate-benzene (1:1, v/v) as the mobile phase, followed by scanning and quantification at 295 nm. Densitometric analysis of leaf extract resulted in compact spots for JA at R = 0.45 ± 0.02. The linear regression analysis showed good relationship with r value. The recovery rate of JA indicated good reproducibility and repeatability of the assay. The statistical analysis proved the reproducibility of the method; therefore, it can be employed for routine quantification of JA in different tissue samples of S. rebaudiana and may also be extrapolated to other biological samples.
[Mh] Termos MeSH primário: Ciclopentanos/análise
Oxilipinas/análise
Stevia/química
[Mh] Termos MeSH secundário: Acetatos
Benzeno
Cromatografia em Camada Delgada/métodos
Ciclopentanos/normas
Oxilipinas/normas
Extratos Vegetais/análise
Folhas de Planta/química
Reprodutibilidade dos Testes
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Acetates); 0 (Cyclopentanes); 0 (Oxylipins); 0 (Plant Extracts); 6RI5N05OWW (jasmonic acid); 76845O8NMZ (ethyl acetate); J64922108F (Benzene)
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170922
[Lr] Data última revisão:
170922
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170311
[St] Status:MEDLINE
[do] DOI:10.1080/14786419.2017.1289199



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