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Pesquisa : B01.650.940.800.575.912.250.150 [Categoria DeCS]
Referências encontradas : 283 [refinar]
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[PMID]:28976990
[Au] Autor:Martín Arroyo T; González-Porto AV; Bartolomé Esteban C
[Ad] Endereço:Laboratorio de Miel y Otros Productos de la Colmena, Centro de Investigación Apícola y Agroambiental de Marchamalo, Instituto Regional de Investigación y Desarrollo Agroalimentario y Forestal, Junta de Comunidades de Castilla La Mancha, Guadalajara, Spain.
[Ti] Título:Viper's bugloss (Echium spp.) honey typing and establishing the pollen threshold for monofloral honey.
[So] Source:PLoS One;12(10):e0185405, 2017.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Honey samples (n = 126) from Castilla-La Mancha (Central Spain) were characterized based on their physicochemical properties and a melissopalynological analysis. The latter showed that Echium pollen type was the dominant palynomorph in most samples, representing at least 30% of the pollen in each sample. As anticipated, a relationship was observed between the proportion of this pollen and the properties of the honey. One goal of this study was to set a threshold that defines the percentage of pollen necessary for Viper's bugloss honey to be considered monofloral or multifloral. This is a mandatory requirement in light of the publication of the European Directive 2014/63/EU establishing the regulations governing the labelling and control of honey to eradicate fraud (BOE n° 147, June 2015). By analyzing how the proportions of Echium pollen type affected the physicochemical and sensory parameters of the honey, the honeys analyzed could be segregated into multifloral and monofloral honeys. The data indicates that the proportion of pollen necessary to discriminate monofloral Viper's bugloss honey lies at 70%.
[Mh] Termos MeSH primário: Boraginaceae/química
Mel/análise
Pólen
[Mh] Termos MeSH secundário: Animais
Abelhas
Análise de Componente Principal
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1711
[Cu] Atualização por classe:171102
[Lr] Data última revisão:
171102
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171005
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0185405


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[PMID]:28573222
[Au] Autor:Balpinar N; Okmen G
[Ad] Endereço:Department of Biology, Faculty of Arts and Science, Mehmet Akif Ersoy University, Burdur 15030, Turkey.
[Ti] Título:THE BIOLOGICAL ACTIVITIES OF ., AN ENDEMIC SPECIES TO TURKEY.
[So] Source:Afr J Tradit Complement Altern Med;14(2):60-64, 2017.
[Is] ISSN:2505-0044
[Cp] País de publicação:Nigeria
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: is the direct reason of mastitis. Mastitis is a disease characterized by pathological changes in mammary glands as well as physical, chemical, bacteriological changes in milk. This disease causes loses in milk yield and quality. In recent years, it is reported that mastitis pathogens have developed a resistance to antibiotics as a natural consequence of widespread use of it. Today's researches are focused on discovering and using new antibiotics against bacteria. The aim of this paper is to examine the antibacterial properties of (an endemic species to Turkey), and its other biological activities. MATERIALS AND METHODS: All of the extracts were tested by disc diffusion assay in order to screen antibacterial activity. MIC values were evaluated as antibacterial activities of plant extracts. The non-enzymatic antioxidative activities including DPPH radical scavenging effects were studied . RESULTS AND CONCLUSIONS: Results shown that the extracts had strong antibacterial effects on three bacteria 17, and CNS-37) and the range of inhibition zone was 4-6mm. This three bacteria screened the lowest sensitivity to 65000 µg /mL concentration. Besides, the extracts were tested for non-enzymatic antioxidant activities. As a result, the methanol extract of the flower displayed a strong antioxidant activity. The various extracts of have different antibacterial and antioxidant properties.
[Mh] Termos MeSH primário: Antibacterianos/farmacologia
Antioxidantes/farmacologia
Boraginaceae
Extratos Vegetais/farmacologia
Staphylococcus aureus/efeitos dos fármacos
[Mh] Termos MeSH secundário: Compostos de Bifenilo/metabolismo
Flores
Mastite/microbiologia
Testes de Sensibilidade Microbiana
Picratos/metabolismo
Folhas de Planta
Caules de Planta
Staphylococcus aureus/crescimento & desenvolvimento
Turquia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Anti-Bacterial Agents); 0 (Antioxidants); 0 (Biphenyl Compounds); 0 (Picrates); 0 (Plant Extracts); DFD3H4VGDH (1,1-diphenyl-2-picrylhydrazyl)
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170816
[Lr] Data última revisão:
170816
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170603
[St] Status:MEDLINE
[do] DOI:10.21010/ajtcam.v14i2.7


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[PMID]:28498992
[Au] Autor:Hoeltgebaum MP; Londoño DMM; Lando AP; Dos Reis MS
[Ad] Endereço:Universidade Federal de Santa Catarina, Centro de Ciências Agrárias, Departamento de Fitotecnia, Rodovia Admar Gonzaga, 1346, Itacorubi, Florianópolis/SC CEP 88.034-001, Brazil
[Ti] Título:Reproductive Strategy of the Polyploid Species Varronia curassavica Jacq. in Restinga Environment.
[So] Source:J Hered;108(4):424-430, 2017 06 01.
[Is] ISSN:1465-7333
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:This study aimed to elucidate the breeding strategies of Varronia curassavica, an important medicinal species associated with Brazilian restinga. This was accomplished by combining phenological and genetic data. Every 2 weeks over a period of 2 years, we measured flowering and fruiting phenology to evaluate the activity and intensity of phenophases (n = 60). We evaluated the mating system, pollen ovule ratio and genotypes from progeny and mother plants using 8 nuclear microsatellite loci. We observed flowering and fruiting of V. curassavica at low intensity throughout the entire year, but with 2 distinct peaks, one of which was seasonal, corresponding to the period of gradual increase of temperature and photoperiod. Overlapping of flowering and fruiting strategies favors gene flow among different groups of individuals and between populations by attraction of fauna throughout the year. Analysis of the mating system indicates that V. curassavica is a typical outcrossed species (t^ = 0.98; pollen/ovule ratio = 7087.50). Combining phenology with genetic studies improved our understanding of the reproductive strategies of this species. The typical outcrossing system of V. curassavica reflects the existence of functional self-incompatibility mechanisms still unaffected by changes in genetic balance by polyploidy.
[Mh] Termos MeSH primário: Boraginaceae/genética
Boraginaceae/fisiologia
Genética Populacional
Poliploidia
[Mh] Termos MeSH secundário: Brasil
Flores/fisiologia
Frutas/fisiologia
Fluxo Gênico
Genótipo
Repetições de Microssatélites
Estações do Ano
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170907
[Lr] Data última revisão:
170907
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170513
[St] Status:MEDLINE
[do] DOI:10.1093/jhered/esx024


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[PMID]:28482839
[Au] Autor:Kheiri A; Amini S; Javidan AN; Saghafi MM; Khorasani G
[Ad] Endereço:Plastic and Reconstructive Surgery Division, Faculty of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
[Ti] Título:The effects of Alkanna tinctoria Tausch on split-thickness skin graft donor site management: a randomized, blinded placebo-controlled trial.
[So] Source:BMC Complement Altern Med;17(1):253, 2017 May 08.
[Is] ISSN:1472-6882
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: A prospective, randomized, placebo-controlled clinical trial was conducted to compare the healing effectiveness of Alkanna tinctoria (L.) Tausch (Boraginaceae) with standard dressing on wound healing at the donor site after removal of the skin graft. METHODS: Enrolled patients were randomly allocated to receive topicalA. tinctoria extract ointment (20%) or standard dressing (dressing with base ointment) daily. Wound healing was assessed using the Bates-Jenson assessment tool at the 2 and 4 weeks after intervention. RESULTS: Decreases in wound score were significantly greater in the A. tinctoria group compared with the placebo group (P <0.05). The surface areas of graft donor sites in the A. tinctoria group were significantly reduced as compared with the control group at day 28 of the intervention (P < 0.05). The proportion of patients in the A. tinctoria group achieving complete wound healing within 2 to 4 weeks was 50% and 96.66%, respectively, significantly higher than in patients receiving standard care: 0% and 23.3%, respectively. CONCLUSIONS: This clinical study showed that A. tinctoria dressing accelerates wound healing after graft harvesting. TRIAL REGISTRATION: IRCT ID: IRCT201511165781N2 .
[Mh] Termos MeSH primário: Boraginaceae/química
Extratos Vegetais/administração & dosagem
Dermatopatias/fisiopatologia
Cicatrização/efeitos dos fármacos
[Mh] Termos MeSH secundário: Adulto
Feminino
Seres Humanos
Masculino
Meia-Idade
Estudos Prospectivos
Dermatopatias/cirurgia
Transplante de Pele
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE; RANDOMIZED CONTROLLED TRIAL
[Nm] Nome de substância:
0 (Plant Extracts)
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170821
[Lr] Data última revisão:
170821
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170510
[St] Status:MEDLINE
[do] DOI:10.1186/s12906-017-1741-0


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[PMID]:28480438
[Au] Autor:Chen J; He Y; Gao T; Zhang L; Zhao Y
[Ad] Endereço:Department of Pharmaceutics, General Hospital of Ningxia Medical University, Yinchuan 750004, China.
[Ti] Título:PREPARATION AND PROPERTIES OF COMPOUND MICROEMULSION GEL.
[So] Source:Afr J Tradit Complement Altern Med;14(3):274-279, 2017.
[Is] ISSN:2505-0044
[Cp] País de publicação:Nigeria
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Compound oil has been clinically applied to treat burns and scalds for a long time. However, it is unstable and inconvenient to use. The aim of this study was to prepare a compound microemulsion gel for transdermal delivery system and evaluate its characteristics. MATERIALS AND METHODS: Based on the solubility of Shikonin, the active component of and the results of phase studies, adequate ratio of each component in microemulsion was determined. The optimized microemulsion gel was prepared using Carbomer 940. The gels were characterized in terms of appearance, preliminary stability test and the content of Shikonin in the compound microemulsion gel with HPLC analysis. RESULTS: The optimized conditions for preparing microemulsion were Tween-80, glycerin, isopropyl myristate (IPM) with the ratio of 6:3:2. The optimal microemulsion gel was obtained with Carbomer 940 (1.0%). CONCLUSION: The prepared compound microemulsion gel showed good stability over time. It is more convenience in application than the previous used formulations.
[Mh] Termos MeSH primário: Boraginaceae/química
Géis/síntese química
Óleos Vegetais/química
[Mh] Termos MeSH secundário: Resinas Acrílicas
Química Farmacêutica/métodos
Estabilidade de Medicamentos
Emulsões
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Acrylic Resins); 0 (Emulsions); 0 (Gels); 0 (Plant Oils); 4Q93RCW27E (carbopol 940)
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170815
[Lr] Data última revisão:
170815
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170509
[St] Status:MEDLINE
[do] DOI:10.21010/ajtcam.v14i3.28


  6 / 283 MEDLINE  
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[PMID]:28390858
[Au] Autor:Zengin G; Ceylan R; Katanic J; Mollica A; Aktumsek A; Boroja T; Matic S; Mihailovic V; Stanic S; Aumeeruddy-Elalfi Z; Yilmaz MA; Mahomoodally MF
[Ad] Endereço:Department of Biology, Faculty of Science, Selcuk University, Campus, Konya, Turkey.
[Ti] Título:Combining in vitro, in vivo and in silico approaches to evaluate nutraceutical potentials and chemical fingerprints of Moltkia aurea and Moltkia coerulea.
[So] Source:Food Chem Toxicol;107(Pt B):540-553, 2017 Sep.
[Is] ISSN:1873-6351
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Methanolic extracts of Moltkia aurea Boiss. (MA) and Moltkia coerulea (Willd.) Lehm. (MC) were investigated for their antioxidant capacity and enzymatic inhibitory potential against acetylcholinesterase, butyrylcholinesterase, α-amylase, α-glucosidase, and tyrosinase in vitro. MA and MC were also explored for their antimicrobial effect, as well as for their possible genotoxic/antigenotoxic potential on Drosophila melanogaster in vivo. The total bioactive components (phenolic (TPC) and flavonoid contents (TFC)) were determined and liquid chromatography-tandem mass spectrometry (LC-MS/MS) metabolite profiling of MA and MC appraised. The plausible docking poses of bioactive compounds to key enzymes were further studied using molecular modelling approach. MA proved to be a better antioxidant with higher TPC and TFC compared to MC. Protocatechuic acid, rutin, hesperidin and malic acid were the most abundant in these extracts. Both MA and MC exhibited antigenotoxic potential with a %R in DNA damage of 60.90 and 53.14% respectively. The docking studies revealed that rutin, hesperidin, and rosmarinic acid have the best scores for all the enzymes tested. MA and MC were found to be rich in phytochemicals with potent antioxidant, antimicrobial, and antigenotoxic activities that can be further studied for the management of neurodegenerative complications, diabetes, and hyperpigmentation.
[Mh] Termos MeSH primário: Boraginaceae/química
Suplementos Nutricionais/análise
Extratos Vegetais/química
[Mh] Termos MeSH secundário: Animais
Antioxidantes/química
Antioxidantes/farmacologia
Drosophila melanogaster/efeitos dos fármacos
Drosophila melanogaster/genética
Compostos Fitoquímicos/química
Compostos Fitoquímicos/farmacologia
Extratos Vegetais/farmacologia
Espectrometria de Massas em Tandem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Antioxidants); 0 (Phytochemicals); 0 (Plant Extracts)
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170907
[Lr] Data última revisão:
170907
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170410
[St] Status:MEDLINE


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[PMID]:28287415
[Au] Autor:Lefort N; LeBlanc R; Surette ME
[Ad] Endereço:Department of Chemistry and Biochemistry, Université de Moncton, Moncton, NB E1A 3E9, Canada. natalie.lefort@umoncton.ca.
[Ti] Título:Dietary Buglossoides Arvensis Oil Increases Circulating n-3 Polyunsaturated Fatty Acids in a Dose-Dependent Manner and Enhances Lipopolysaccharide-Stimulated Whole Blood Interleukin-10-A Randomized Placebo-Controlled Trial.
[So] Source:Nutrients;9(3), 2017 Mar 10.
[Is] ISSN:2072-6643
[Cp] País de publicação:Switzerland
[La] Idioma:eng
[Ab] Resumo:(Ahiflower) oil is a dietary oil rich in stearidonic acid (20% SDA; 18:4 -3). The present randomized, double blind, placebo-controlled clinical trial investigated the effects of three Ahiflower oil dosages on omega-3 polyunsaturated fatty acid (PUFA) content of plasma and mononuclear cells (MCs) and of the highest Ahiflower dosage on stimulated cytokine production in blood. Healthy subjects ( = 88) consumed 9.7 mL per day for 28 days of 100% high oleic sunflower oil (HOSO); 30% Ahiflower oil (Ahi) + 70% HOSO; 60% Ahi + 40% HOSO; and 100% Ahi. No clinically significant changes in blood and urine chemistries, blood lipid profiles, hepatic and renal function tests nor hematology were measured. Linear mixed models (repeated measures design) probed for differences in time, and time × treatment interactions. Amongst significant changes, plasma and MC eicosapentaenoic acid (EPA, 20:5 -3) levels increased from baseline at day 28 in all Ahiflower groups ( < 0.05) and the increase was greater in all Ahiflower groups compared to the HOSO control (time × treatment interactions; < 0.05). Similar results were obtained for α-linolenic acid (ALA, 18:3 -3), eicosatetraenoic acid (ETA, 20:4 -3), and docosapentaenoic acid (DPA, 22:5 -3) content; but not docosahexaenoic acid (DHA, 22:6 -3). Production of interleukin-10 (IL-10) was increased in the 100% Ahiflower oil group compared to 100% HOSO group ( < 0.05). IL-10 production was also increased in lipopolysaccharide (LPS)-stimulated M2-differentiated THP-1 macrophage-like cells in the presence of 20:4 -3 or EPA ( < 0.05). Overall; this indicates that the consumption of Ahiflower oil is associated with an anti-inflammatory phenotype in healthy subjects.
[Mh] Termos MeSH primário: Boraginaceae/química
Ácidos Graxos Ômega-3/administração & dosagem
Ácidos Graxos Ômega-3/sangue
Interleucina-10/sangue
Lipopolissacarídeos/sangue
Óleos Vegetais/administração & dosagem
[Mh] Termos MeSH secundário: Adulto
Glicemia/metabolismo
Índice de Massa Corporal
HDL-Colesterol/sangue
LDL-Colesterol/sangue
Ácidos Docosa-Hexaenoicos/administração & dosagem
Ácidos Docosa-Hexaenoicos/sangue
Relação Dose-Resposta a Droga
Método Duplo-Cego
Ácido Eicosapentaenoico/administração & dosagem
Ácido Eicosapentaenoico/sangue
Ácidos Graxos Ômega-3/análise
Feminino
Seres Humanos
Leucócitos Mononucleares/efeitos dos fármacos
Leucócitos Mononucleares/metabolismo
Masculino
Cooperação do Paciente
Óleos Vegetais/química
Óleo de Girassol
Resultado do Tratamento
Triglicerídeos/sangue
Ácido alfa-Linolênico/administração & dosagem
Ácido alfa-Linolênico/sangue
[Pt] Tipo de publicação:JOURNAL ARTICLE; RANDOMIZED CONTROLLED TRIAL
[Nm] Nome de substância:
0 (Blood Glucose); 0 (Cholesterol, HDL); 0 (Cholesterol, LDL); 0 (Fatty Acids, Omega-3); 0 (IL10 protein, human); 0 (Lipopolysaccharides); 0 (Plant Oils); 0 (Sunflower Oil); 0 (Triglycerides); 0RBV727H71 (alpha-Linolenic Acid); 130068-27-8 (Interleukin-10); 25167-62-8 (Docosahexaenoic Acids); AAN7QOV9EA (Eicosapentaenoic Acid); P4CEK3495O (stearidonic acid)
[Em] Mês de entrada:1709
[Cu] Atualização por classe:171116
[Lr] Data última revisão:
171116
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170314
[St] Status:MEDLINE


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[PMID]:28140740
[Au] Autor:Dresler S; Szymczak G; Wójcik M
[Ad] Endereço:a Department of Plant Physiology , Maria Curie-Sklodowska University , Lublin , Poland.
[Ti] Título:Comparison of some secondary metabolite content in the seventeen species of the Boraginaceae family.
[So] Source:Pharm Biol;55(1):691-695, 2017 Dec.
[Is] ISSN:1744-5116
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:CONTEXT: The Boraginaceae family comprises plants that have important therapeutic and cosmetic applications. Their pharmacological effect is related to the presence of naphthaquinones, flavonoids, terpenoids, phenols, or purine derivative - allantoin. OBJECTIVE: In the present study, comparison of some secondary metabolite content and phytochemical relationship between 17 species of the Boraginaceae family were analyzed. MATERIALS AND METHODS: High performance capillary electrophoresis (HPCE) was used to perform a chemometric analysis in the following Boraginaceae species: Anchusa azurea Mill., Anchusa undulata L., Borago officinalis L., Buglossoides purpurocaerulea (L.) I.M. Johnst., Cerinthe minor L., Cynoglossum creticum Mill, Echium italicum L., Echium russicum J.F. Gmel., Echium vulgare L., Lindelofia macrostyla (Bunge) Popov (syn. Lindelofia anchusoides (Lindl.) Lehm.), Lithospermum officinale L., Nonea lutea (Desr.) DC., Omphalodes verna Moench (syn. Cynoglossum omphaloides L.), Pulmonaria mollis Wulfen ex Hornem., Pulmonaria obscura Dumort., Symphytum cordatum Waldst. & Kit ex Willd., and Symphytum officinale L. RESULTS: Six active compounds in shoot extracts (allantoin, p-hydroxybenzoic acid, rutin, hydrocaffeic acid, rosmarinic acid, and chlorogenic acid) and four compounds in root extracts (allantoin, hydrocaffeic acid, rosmarinic acid, and shikonin) were identified. The presence and abundance of these compounds were used for the characterization of the species and for revealing their phytochemical similarity and differentiation. DISCUSSION AND CONCLUSION: The present study provides the first comprehensive report of the extraction and quantification of several compounds in Boraginaceae species (some of them for the first time). Among the 17 species studied, species with potentially high pharmacological activity were recognized.
[Mh] Termos MeSH primário: Boraginaceae/metabolismo
[Mh] Termos MeSH secundário: Boraginaceae/química
Eletroforese Capilar
Compostos Fitoquímicos/análise
Extratos Vegetais/análise
[Pt] Tipo de publicação:COMPARATIVE STUDY; JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Phytochemicals); 0 (Plant Extracts)
[Em] Mês de entrada:1703
[Cu] Atualização por classe:170306
[Lr] Data última revisão:
170306
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170201
[St] Status:MEDLINE
[do] DOI:10.1080/13880209.2016.1265986


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[PMID]:28118832
[Au] Autor:Civra A; Francese R; Sinato D; Donalisio M; Cagno V; Rubiolo P; Ceylan R; Uysal A; Zengin G; Lembo D
[Ad] Endereço:Department of Clinical and Biological Sciences, University of Torino, S. Luigi Gonzaga Hospital, Regione Gonzole, 10, 10043, Orbassano, Torino, Italy.
[Ti] Título:In vitro screening for antiviral activity of Turkish plants revealing methanolic extract of Rindera lanata var. lanata active against human rotavirus.
[So] Source:BMC Complement Altern Med;17(1):74, 2017 Jan 24.
[Is] ISSN:1472-6882
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Human rotavirus (HRoV) is the leading cause of severe gastroenteritis in infants and children under the age of five years. No specific antiviral drug is available for HRoV infections and the treatment of viral diarrhea is mainly based on rehydration and zinc treatment. In this study, we explored medicinal plants endemic to Turkey flora as a source of anti-HRoV compunds. METHODS: We performed an antiviral screening on Ballota macrodonta, Salvia cryptantha and Rindera lanata extracts by focus reduction assay. The extract with the highest selectivity index (SI) was selected; its antiviral activity was further confirmed against other HRoV strains and by virus yield reduction assay. The step of viral replicative cycle putatively inhibited was investigated by in vitro assays. RESULTS: The methanolic extract of R. lanata (Boraginaceae) showed the most favourable selectivity index. This extract exhibited a dose-dependent inhibitory activity against three different HRoV strains (EC values ranging from 5.8 µg/ml to 25.5 µg/ml), but was inactive or barely active against other RNA viruses, namely human rhinovirus and respiratory syncytial virus. The R. lanata extract targets the early steps of HRoV infection, likely by hampering virus penetration into the cells. CONCLUSION: These results make the R. lanata methanolic extract a promising starting material for a bioguided-fractionation aimed at identifying anti-HRoV compounds. Further work is required to isolate the active principle and assess its clinical potential.
[Mh] Termos MeSH primário: Antivirais/análise
Boraginaceae/química
Infecções por Rotavirus/tratamento farmacológico
Rotavirus/efeitos dos fármacos
[Mh] Termos MeSH secundário: Animais
Antivirais/farmacologia
Antivirais/uso terapêutico
Linhagem Celular
Cercopithecus aethiops
Testes de Sensibilidade Microbiana
Fitoterapia
Extratos Vegetais/química
Extratos Vegetais/farmacologia
Extratos Vegetais/uso terapêutico
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Antiviral Agents); 0 (Plant Extracts)
[Em] Mês de entrada:1702
[Cu] Atualização por classe:170220
[Lr] Data última revisão:
170220
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170126
[St] Status:MEDLINE
[do] DOI:10.1186/s12906-017-1560-3


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[PMID]:28039130
[Au] Autor:Ferrero V; Barrett SC; Rojas D; Arroyo J; Navarro L
[Ad] Endereço:Department of Plant Biology and Soil Sciences, Faculty of Biology, University of Vigo, As Lagoas-Marcosende 36200 Vigo, Spain victoferrero@gmail.com.
[Ti] Título:Associations between sex-organ deployment and morph bias in related heterostylous taxa with different stylar polymorphisms.
[So] Source:Am J Bot;104(1):50-61, 2017 Jan.
[Is] ISSN:1537-2197
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:PREMISE OF THE STUDY: Populations of heterostylous species are characterized by two or three floral morphs with reciprocal positioning of stigmas and anthers. Theoretical models predict equal morph frequencies (isoplethy) when disassortative mating is prevalent in populations, but biased morph ratios may occur when variation in the expression of heterostyly causes deviations from intermorph mating. METHODS: We explore the role of sex-organ deployment in governing morph ratios in two closely related genera of Boraginaceae, exhibiting striking variation in floral traits associated with the heterostylous syndrome. We sampled 66 populations of six species of Glandora and 39 populations of three species of Lithodora across their distributional range in the Mediterranean. In each population we estimated morph ratios and measured several floral traits. We used phylogenetically corrected and noncorrected regressions to test the hypothesis that differences in sex-organ reciprocity and herkogamy are associated with deviations from isoplethy. KEY RESULTS: Biased morph ratios occurred in 24% of populations, particularly in Lithodora. Populations biased for the long-styled morph (L-morph) were more frequent than the short-styled morph (S-morph). Distylous species were less likely to exhibit biased ratios than species with stigma-height dimorphism. In Lithodora fruticosa, a species lacking reciprocity, decreased herkogamy in the S-morph was associated with increasing L-morph bias, perhaps resulting from self-interference. CONCLUSION: Striking variation in the expression of heterostyly in Glandora and Lithodora is associated with biased morph ratios, which probably result from pollinator-mediated mating asymmetries within populations.
[Mh] Termos MeSH primário: Boraginaceae/fisiologia
Flores/fisiologia
Pólen/fisiologia
Polinização/fisiologia
[Mh] Termos MeSH secundário: Evolução Biológica
Boraginaceae/anatomia & histologia
Boraginaceae/classificação
Flores/anatomia & histologia
Geografia
Região do Mediterrâneo
Modelos Anatômicos
Pólen/anatomia & histologia
Reprodução/fisiologia
Especificidade da Espécie
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170815
[Lr] Data última revisão:
170815
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170101
[St] Status:MEDLINE
[do] DOI:10.3732/ajb.1600345



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