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Pesquisa : B01.650.940.800.575.912.250.150.188 [Categoria DeCS]
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[PMID]:28638880
[Au] Autor:Khattab HAH; Abdallah IZA; Yousef FM; Huwait EA
[Ad] Endereço:Food and Nutrition Department, Faculty of Home Economics, King Abdulaziz University, Jeddah, Saudi Arabia.
[Ti] Título:EFFICIENCY OF BORAGE SEEDS OIL AGAINST GAMMA IRRADIATION-INDUCED HEPATOTOXICITY IN MALE RATS: POSSIBLE ANTIOXIDANT ACTIVITY.
[So] Source:Afr J Tradit Complement Altern Med;14(4):169-179, 2017.
[Is] ISSN:2505-0044
[Cp] País de publicação:Nigeria
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Borage ( L.) is an annual herbaceous plant of great interest because its oil contains a high percentage of γ-linolenic acid (GLA). The present work was carried out to detect fatty acids composition of the oil extracted from borage seeds (BO) and its potential effectiveness against γ-irradiation- induced hepatotoxicity in male rats. MATERIALS AND METHODS: GC-MS analysis of fatty acids methyl esters of BO was performed to identify fatty acids composition. Sixty rats were divided into five groups (12 rats each): Control, irradiated; rats were exposed to (6.5 Gy) of whole body γ-radiation, BO (50 mg/kg b.wt), irradiated BO post-treated and irradiated BO prepost-treated. Six rats from each group were sacrificed at two time intervals 7 and 15 days post-irradiation. Serum aspartate aminotransferase (AST), alanine aminotransferase (ALT), gamma glutamyl transferase (GGT) levels, lipids profile, as well as serum and hepatic reduced glutathione (GSH) and lipid peroxide (malondialdehyde) (MDA) levels were assessed. Histopathological examination of liver sections were also carried out. RESULTS: The results showed that the high contents of BO extracted by cold pressing, were linoleic acid (34.23%) and GLA (24.79%). Also, oral administration of BO significantly improved serum levels of liver enzymes, lipids profile, as well as serum and hepatic GSH and MDA levels (p<0.001) as compared with irradiated rats after 15 days post irradiation. Moreover, it exerted marked amelioration against irradiation-induced histopathological changes in liver tissues. The improvement was more pronounced in irradiated BO prepost-treated group than irradiated BO post-treated. CONCLUSION: BO has a beneficial role in reducing hepatotoxicity and oxidative stress induced by radiation exposure. Therefore, BO may be used as a beneficial supplement for patients during radiotherapy treatment.
[Mh] Termos MeSH primário: Antioxidantes/química
Borago/química
Raios gama/efeitos adversos
Hepatopatias/tratamento farmacológico
Fígado/efeitos da radiação
Óleos Vegetais/química
Ácido gama-Linolênico/química
[Mh] Termos MeSH secundário: Animais
Antioxidantes/administração & dosagem
Ácidos Graxos/química
Cromatografia Gasosa-Espectrometria de Massas
Glutationa/metabolismo
Seres Humanos
Fígado/lesões
Fígado/metabolismo
Hepatopatias/etiologia
Masculino
Malondialdeído/metabolismo
Estresse Oxidativo/efeitos dos fármacos
Estresse Oxidativo/efeitos da radiação
Óleos Vegetais/administração & dosagem
Ratos
Sementes/química
Ácido gama-Linolênico/administração & dosagem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Antioxidants); 0 (Fatty Acids); 0 (Plant Oils); 0 (borage oil); 4Y8F71G49Q (Malondialdehyde); 78YC2MAX4O (gamma-Linolenic Acid); GAN16C9B8O (Glutathione)
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170817
[Lr] Data última revisão:
170817
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170623
[St] Status:MEDLINE
[do] DOI:10.21010/ajtcam.v14i4.20


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[PMID]:28499255
[Au] Autor:Kalhor HR; Ashrafian H
[Ad] Endereço:Biochemistry Research Laboratory, Department of Chemistry, Sharif University of Technology, Tehran, Iran. Electronic address: kalhor@sharif.edu.
[Ti] Título:Identification of an aspidospermine derivative from borage extract as an anti-amyloid compound: A possible link between protein aggregation and antimalarial drugs.
[So] Source:Phytochemistry;140:134-140, 2017 Aug.
[Is] ISSN:1873-3700
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:A number of human diseases, including Alzheimer's and Parkinson's have been linked to amyloid formation. To search for an anti-amyloidogenic product, alkaloid enriched extract from borage leaves was examined for anti-amyloidogenic activity using Hen Egg White Lysozyme (HEWL) as a model protein. After isolation of the plant extract using rHPLC, only one fraction indicated a significant bioactivity. TEM analysis confirmed a remarkable reduction of amyloid fibrils in the presence of the bioactive fraction. To identify the effective substance in the fraction, mass spectrometry, FTIR, and NMR were performed. Our analyses determined that the bioactive compound as 1-acetyl-19,21-epoxy-15,16-dimethoxyaspidospermidine-17-ol, a derivative of aspidospermine. To investigate the mechanism of the inhibition, ANS binding, intrinsic fluorescence, and amide I content were performed in the presence of the bioactive compound. All the results confirmed the role of the compound in assisting the proper folding of the protein. In addition, molecular docking indicated the aspidospermine derivative binds the amyloidogenic region of the protein. Our results show that the alkaloid extracted from borage leaves reduces protein aggregation mediating through structural elements of the protein, promoting the correct folding of lysozyme. Since a number of aspidospermine compounds have been shown to possess potent antimalarial activities, the action of compound identified in the present study suggests a possible link between protein aggregation and aspidospermine drugs.
[Mh] Termos MeSH primário: Amiloide/antagonistas & inibidores
Borago/química
Alcaloides de Indol/química
Dobramento de Proteína/efeitos dos fármacos
Quinolinas/química
[Mh] Termos MeSH secundário: Antimaláricos/química
Alcaloides de Indol/isolamento & purificação
Simulação de Acoplamento Molecular
Muramidase/química
Extratos Vegetais/química
Folhas de Planta/química
Agregação Patológica de Proteínas/prevenção & controle
Quinolinas/isolamento & purificação
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Amyloid); 0 (Antimalarials); 0 (Indole Alkaloids); 0 (Plant Extracts); 0 (Quinolines); EC 3.2.1.- (hen egg lysozyme); EC 3.2.1.17 (Muramidase); U1475W62Q5 (aspidospermine)
[Em] Mês de entrada:1707
[Cu] Atualização por classe:170717
[Lr] Data última revisão:
170717
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170513
[St] Status:MEDLINE


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[PMID]:27005499
[Au] Autor:Jaradat NA; Damiri B; Abualhasan MN
[Ad] Endereço:Pharmaceutical Chemistry and Technology Division, Department of Pharmacy, Faculty of Medicine and Health Sciences, An-Najah National University, Nablus, State of Palestine.
[Ti] Título:Antioxidant evaluation for Urtica urens, Rumex cyprius and Borago officinalis edible wild plants in Palestine.
[So] Source:Pak J Pharm Sci;29(1 Suppl):325-30, 2016 Jan.
[Is] ISSN:1011-601X
[Cp] País de publicação:Pakistan
[La] Idioma:eng
[Ab] Resumo:Natural plants products are one of the famous and commonly utilized remedies used in fighting diseases. This study was conducted to evaluate antioxidant activity of plants commonly used in Palestine (Urtica urens, Rumex cyprius and Borago officinalis). Free radical scavenging activity method was evaluated by using 2,2-diphenyl-1-picryl-hydrazyl-hydrate. The result show that the overall antioxidant activity of Rumex cyprius was the highest among the plants, followed by Urtica urens, and Borago officinalis; respectively. The (IC(50)) values of the methanolic extracts were 29.70±0.60µg/ml, 5.07±0.49µg/ml, 39.92± 0.52 µg/ml for Urtica urens, Rumex cyprius and Borago officinalis respectively. The results of this study revealed that these edible plants have high antioxidant activity and therefore they can provide natural sources of antioxidants and can be useful in preventing various diseases including cancer. These exhibited properties propose that such plants extracts can possibly be used as natural preservatives in the food and pharmaceutical industries and further characterization of Rumex cyprius constituents is needed.
[Mh] Termos MeSH primário: Antioxidantes/química
Borago/química
Plantas Comestíveis/química
Rumex/química
Urticaceae/química
[Mh] Termos MeSH secundário: Antioxidantes/farmacologia
Compostos de Bifenilo
Depuradores de Radicais Livres/química
Depuradores de Radicais Livres/farmacologia
Israel
Picratos
Extratos Vegetais/química
Extratos Vegetais/farmacologia
Folhas de Planta/química
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Antioxidants); 0 (Biphenyl Compounds); 0 (Free Radical Scavengers); 0 (Picrates); 0 (Plant Extracts); DFD3H4VGDH (1,1-diphenyl-2-picrylhydrazyl)
[Em] Mês de entrada:1608
[Cu] Atualização por classe:161126
[Lr] Data última revisão:
161126
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160324
[St] Status:MEDLINE


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[PMID]:26797631
[Au] Autor:Lozano-Baena MD; Tasset I; Muñoz-Serrano A; Alonso-Moraga Á; de Haro-Bailón A
[Ad] Endereço:Department of Plant Breeding, Institute of Sustainable Agriculture, CSIC, Av. Menéndez Pidal s/n, Córdoba E-14004, Spain. mdlozano@ias.csic.es.
[Ti] Título:Cancer Prevention and Health Benefices of Traditionally Consumed Borago officinalis Plants.
[So] Source:Nutrients;8(1), 2016 Jan 18.
[Is] ISSN:2072-6643
[Cp] País de publicação:Switzerland
[La] Idioma:eng
[Ab] Resumo:Nowadays, healthy eating is increasing the demand of functional foods by societies as sources of bioactive products with healthy qualities. For this reason, we tested the safety of the consumption of Borago officinalis L. and its main phenolic components as well as the possibility of its use as a nutraceutical plant to help in cancer prevention. The in vivo Drosophila Somatic Mutation and Recombination Test (SMART) and in vitro HL-60 human cell systems were performed, as well-recognized methods for testing genotoxicity/cytotoxicity of bioactive compounds and plant products. B. officinalis and the tested compounds possess antigenotoxic activity. Moreover, B. officinalis wild type cultivar exerts the most antigenotoxic values. Cytotoxic effect was probed for both cultivars with IC50 values of 0.49 and 0.28 mg · mL(-1) for wild type and cultivated plants respectively, as well as their constituent rosmarinic acid and the assayed phenolic mixture (IC50 = 0.07 and 0.04 mM respectively). B. officinalis exerts DNA protection and anticarcinogenic effects as do its component rosmarinic acid and the mixture of the main phenolics presented in the plant. In conclusion, the results showed that B. officinalis may represent a high value plant for pleiotropic uses and support its consumption as a nutraceutical plant.
[Mh] Termos MeSH primário: Anticarcinógenos/farmacocinética
Borago/metabolismo
Neoplasias/prevenção & controle
[Mh] Termos MeSH secundário: Animais
Disponibilidade Biológica
Borago/química
Cinamatos/farmacocinética
Citotoxicidade Imunológica
Citotoxinas/farmacocinética
Depsídeos/farmacocinética
Células HL-60
Seres Humanos
Concentração Inibidora 50
Testes de Mutagenicidade/métodos
Fenóis/farmacocinética
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Anticarcinogenic Agents); 0 (Cinnamates); 0 (Cytotoxins); 0 (Depsides); 0 (Phenols); MQE6XG29YI (rosmarinic acid)
[Em] Mês de entrada:1609
[Cu] Atualização por classe:170428
[Lr] Data última revisão:
170428
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160123
[St] Status:MEDLINE


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[PMID]:26382913
[Au] Autor:Samy MN; Hamed AN; Sugimoto S; Otsuka H; Kamel MS; Matsunami K
[Ad] Endereço:a Department of Pharmacognosy, Graduate School of Biomedical & Health Sciences , Hiroshima University , Hiroshima , Japan.
[Ti] Título:Officinalioside, a new lignan glucoside from Borago officinalis L.
[So] Source:Nat Prod Res;30(8):967-72, 2016.
[Is] ISSN:1478-6427
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:A new lignan glucoside, officinalioside (1), was isolated from n-BuOH fraction of the aerial parts of Borago officinalis L., together with four known compounds: actinidioionoside (2), roseoside (3), crotalionoside C (4) and kaempferol 3-O-ß-D-galactopyranoside (5). The structure of the new compound was established by means of spectroscopic and chemical analyses. Compounds 1 and 2 showed a moderate DPPH radical scavenging activity (IC50: 52.6 ± 1.70 and 41.3 ± 0.25 µM, respectively) comparable with that of the standard trolox (16.6 ± 2.2 µM) without any significant cytotoxicity towards human cell line A549 (IC50 > 100 µM).
[Mh] Termos MeSH primário: Borago/química
Lignanas/química
[Mh] Termos MeSH secundário: Linhagem Celular Tumoral
Depuradores de Radicais Livres/química
Depuradores de Radicais Livres/isolamento & purificação
Glucosídeos/química
Glucosídeos/isolamento & purificação
Seres Humanos
Quempferóis/química
Quempferóis/isolamento & purificação
Lignanas/isolamento & purificação
Estrutura Molecular
Norisoprenoides/química
Norisoprenoides/isolamento & purificação
Extratos Vegetais/química
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Free Radical Scavengers); 0 (Glucosides); 0 (Kaempferols); 0 (Lignans); 0 (Norisoprenoids); 0 (Plant Extracts); 0 (crotalionoside C); 0 (officinalioside); 0 (roseoside)
[Em] Mês de entrada:1611
[Cu] Atualização por classe:161230
[Lr] Data última revisão:
161230
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:150919
[St] Status:MEDLINE
[do] DOI:10.1080/14786419.2015.1088540


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[PMID]:26045584
[Au] Autor:Khajeh M; Moghaddam ZS; Bohlooli M; Khajeh A
[Ad] Endereço:Department of Chemistry, University of Zabol, P.O. Box 98615-538, Zabol, Iran m_khajeh@uoz.ac.ir.
[Ti] Título:Modeling of dispersive liquid-liquid microextraction for determination of essential oil from Borago officinalis L. by using combination of artificial neural network and genetic algorithm method.
[So] Source:J Chromatogr Sci;53(10):1801-7, 2015 Nov-Dec.
[Is] ISSN:1945-239X
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Dispersive liquid-liquid microextraction (DLLME) coupled with gas chromatography was applied for the extraction and determination of essential oil constituents of the Borago officinalis L. In this study, an experimental data-based artificial neural network (ANN) model was constructed to describe the performance of DLLME method for various operating conditions. The volume of extraction and dispersive solvents, extraction time and salt effect were the input variables of this process, whereas the extraction efficiency was the output. The ANN method was found to be capable of modeling this procedure accurately. The overall agreement between the experimental data and ANN predictions was satisfactory showing a determination coefficient of 0.982. The optimum operating condition was then determined by the genetic algorithm method. The optimal conditions were 248 µL volume of extraction solvent, 260 µL volume of dispersive solvent, 2.5 min extraction time and 0.16 mol L(-1) of salt. The limit of detection and linear dynamic range were 0.15-24.0 and 1.2-1,800 ng mL(-1), respectively. The main components of the essential oil were δ-cadinene (31.02%), carvacrol (24.91%), α-pinene (20.89%) and α-cadinol (16.47%).
[Mh] Termos MeSH primário: Borago/química
Rede Nervosa
Óleos Voláteis/análise
[Mh] Termos MeSH secundário: Algoritmos
Microextração em Fase Líquida
Modelos Teóricos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Oils, Volatile)
[Em] Mês de entrada:1606
[Cu] Atualização por classe:151113
[Lr] Data última revisão:
151113
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:150606
[St] Status:MEDLINE
[do] DOI:10.1093/chromsci/bmv065


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[PMID]:25415370
[Au] Autor:Ratz-Lyko A; Arct J; Pytkowska K; Majewski S
[Ad] Endereço:Department of Cosmetology, Academy of Cosmetics and Health Care , Warsaw , Poland.
[Ti] Título:In vivo and ex vivo evaluation of cosmetic properties of seedcakes.
[So] Source:J Cosmet Laser Ther;17(2):109-15, 2015 Apr.
[Is] ISSN:1476-4180
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:The seedcakes are a potential source of natural bioactive substances: antioxidants, protein, and carbohydrates. Thus, they may scavenge free radicals and have an effect on the stratum corneum hydration and epidermal barrier function. The aim of the study was to evaluate the in vivo and ex vivo properties of emulsions with the seedcake extracts using the pH meter, corneometer, tewameter, methyl nicotinate model of micro-inflammation in human skin, and tape stripping of the stratum corneum. The in vivo and ex vivo studies showed that the emulsions with Oenothera biennis, Borago officinalis, and Nigella sativa seedcake extracts have anti-inflammatory and antioxidant activity. The 6-week topical application of the emulsions with the B. officinalis and N. sativa seedcakes significantly reduced skin irritation and influenced the improvement of the skin hydration and epidermal barrier function compared with placebo. The seedcakes due to their antioxidant and anti-inflammatory activities have potential application in anti-aging, moisturizing, mitigating, and protective cosmetics.
[Mh] Termos MeSH primário: Anti-Inflamatórios/farmacologia
Antioxidantes/farmacologia
Borago
Nigella sativa
Oenothera biennis
Extratos Vegetais/farmacologia
Pele/efeitos dos fármacos
[Mh] Termos MeSH secundário: Adolescente
Adulto
Anti-Inflamatórios/administração & dosagem
Antioxidantes/administração & dosagem
Emulsões
Epiderme/efeitos dos fármacos
Feminino
Seres Humanos
Concentração de Íons de Hidrogênio
Masculino
Meia-Idade
Extratos Vegetais/administração & dosagem
Sementes
Água/metabolismo
Adulto Jovem
[Pt] Tipo de publicação:CLINICAL TRIAL; JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Anti-Inflammatory Agents); 0 (Antioxidants); 0 (Emulsions); 0 (Plant Extracts); 059QF0KO0R (Water)
[Em] Mês de entrada:1601
[Cu] Atualização por classe:150416
[Lr] Data última revisão:
150416
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:141122
[St] Status:MEDLINE
[do] DOI:10.3109/14764172.2014.988726


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[PMID]:25360856
[Au] Autor:Morteza E; Akbari GA; Moaveni P; Alahdadi I; Bihamta MR; Hasanloo T; Joorabloo A
[Ad] Endereço:a Depatment of Agronomy and Plant Breeding Sciences , College of Aburaihan, University of Tehran , Pakdasht , Tehran , Iran.
[Ti] Título:Compositions of the seed oil of the Borago officinalis from Iran.
[So] Source:Nat Prod Res;29(7):663-6, 2015.
[Is] ISSN:1478-6427
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:In order to investigate the composition of borage (Borago officinalis L.) seed oil, this research was performed under the field conditions at Shahriyar and Garmsar zones, Iran during the 2012 planting year. The oil yield of borage was 31.46% and 33.7% at Shahriyar and Garmsar zone, respectively, and nine and eight fatty acids were identified in the seed oil of borage at Shahriyar and Garmsar, respectively - palmitic, linoleic, stearic and γ-linolenic acids were dominant in the seed oil of borage from both zones. Unsaturated fatty acid content was more than the saturated fatty acids in both zones. The ratio of linoleic acid and α-linolenic acid in the borage cultivated at Shahriyar and Garmsar zones was 2.13 and 2.29. The fatty acid profile of Garmsar borage, oleic and oleic/linoleic acid ratio, increased. Locations with different ecological conditions resulted in changes in both seed oil content and fatty acid profile of borage.
[Mh] Termos MeSH primário: Borago/química
Ácidos Graxos/química
Óleos Vegetais/química
Sementes/química
[Mh] Termos MeSH secundário: Irã (Geográfico)
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Fatty Acids); 0 (Plant Oils)
[Em] Mês de entrada:1506
[Cu] Atualização por classe:150326
[Lr] Data última revisão:
150326
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:141101
[St] Status:MEDLINE
[do] DOI:10.1080/14786419.2014.971793


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[PMID]:25060965
[Au] Autor:Zargooshnia S; Shahidi S; Ghahremanitamadon F; Nikkhah A; Mehdizadeh M; Soleimani Asl S
[Ad] Endereço:Neurophysiology Research Center, Hamadan University of Medical Sciences, Hamadan, Iran.
[Ti] Título:The protective effect of Borago Officinalis extract on amyloid ß (25-35)-induced long term potentiation disruption in the dentate gyrus of male rats.
[So] Source:Metab Brain Dis;30(1):151-6, 2015 Feb.
[Is] ISSN:1573-7365
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Alzheimer's disease (AD) begins with impairment in synaptic functions before developing into later neurodegeneration and neural loss. In the present study we have examined the protective effects of Borago Officinalis (borage) extract on amyloid ß (Aß)--Induced long term potentiation (LTP) disruption in hippocampal dentate gyrus (DG). Wistar male rats received intrahippocampal (IHP) injection of the Aß (25-35) and borage extract throughout gestation (100 mg/kg). LTP in perforant path- DG synapses was assessed using electrophysiology method and field excitatory post- synaptic potential (fEPSP) slope and population spike (PS) amplitude were measured by 400 Hz tetanization. Finally, the total thiol content of hippocampus was measured using colorimetric reaction based on the Ellman's method. The results showed that Aß (25-35) significantly decreased fEPSP slope and SP amplitude comparing with the control and sham group, whereas borage extract administration increased these parameters compared to the Aß group. Aß induced a remarkable decrease in total thiol content of hippocampus and borage prevented the decrease of the hippocampal total sulfhydryl (SH) groups. This data suggest that Aß (25-35) can effectively inhibit LTP in the granular cells of the DG in hippocampus, and borage supplementation reverse the synaptic plasticity in DG following Aß treatment and that borage consumption may lead to an improvement of AD-induced cognitive dysfunction.
[Mh] Termos MeSH primário: Peptídeos beta-Amiloides/toxicidade
Antioxidantes/farmacologia
Borago/química
Giro Denteado/efeitos dos fármacos
Potenciação de Longa Duração/efeitos dos fármacos
Transtornos da Memória/tratamento farmacológico
Fragmentos de Peptídeos/toxicidade
Extratos Vegetais/farmacologia
[Mh] Termos MeSH secundário: Animais
Avaliação Pré-Clínica de Medicamentos
Hipocampo/química
Hipocampo/efeitos dos fármacos
Injeções
Masculino
Transtornos da Memória/induzido quimicamente
Fitoterapia
Distribuição Aleatória
Ratos
Ratos Wistar
Compostos de Sulfidrila/análise
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Amyloid beta-Peptides); 0 (Antioxidants); 0 (Peptide Fragments); 0 (Plant Extracts); 0 (Sulfhydryl Compounds); 0 (amyloid beta-protein (25-35))
[Em] Mês de entrada:1603
[Cu] Atualização por classe:171030
[Lr] Data última revisão:
171030
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:140726
[St] Status:MEDLINE
[do] DOI:10.1007/s11011-014-9594-4


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[PMID]:25105953
[Au] Autor:Salem N; Msaada K; Hammami M; Jday A; Salem S; Limam F; Marzouk B
[Ad] Endereço:a Laboratory of Bioactive Substances, Biotechnology Center in Borj-Cedria Technopol , BP 901, 2050 Hammam-Lif , Tunisia.
[Ti] Título:Variations in Tunisian borage essential oil profiles and their antioxidant activities during flowering.
[So] Source:Nat Prod Res;28(21):1919-22, 2014.
[Is] ISSN:1478-6427
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:This study was conducted to examine the chemical composition and antioxidant activity of the essential oils (EOs) of Borago officinalis stem during its flowering stage. The EO composition was characterised by high proportions of E,E-decadienal, the main compound of monoterpene hydrocarbon class, with values varying from 47.08% to 55.28% in two Tunisian regions. The region of Korba exhibited the highest scavenging activity (2.05 mg/mL) by comparison with Beja region. In all tests, the fructification stage showed the best antioxidant activity of all flowering stages.
[Mh] Termos MeSH primário: Antioxidantes/química
Borago/química
Flores/crescimento & desenvolvimento
Óleos Vegetais/análise
Ácido gama-Linolênico/análise
[Mh] Termos MeSH secundário: Cromatografia Gasosa-Espectrometria de Massas
Monoterpenos/análise
Óleos Voláteis/química
Tunísia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Antioxidants); 0 (Monoterpenes); 0 (Oils, Volatile); 0 (Plant Oils); 0 (borage oil); 78YC2MAX4O (gamma-Linolenic Acid)
[Em] Mês de entrada:1501
[Cu] Atualização por classe:140924
[Lr] Data última revisão:
140924
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:140809
[St] Status:MEDLINE
[do] DOI:10.1080/14786419.2014.947495



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