Base de dados : MEDLINE
Pesquisa : B01.650.940.800.575.912.250.198.500.992 [Categoria DeCS]
Referências encontradas : 222 [refinar]
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  1 / 222 MEDLINE  
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[PMID]:29297846
[Au] Autor:Zhang YG; Zhou XK; Guo JW; Xiao M; Wang HF; Wang Y; Bobodzhanova K; Li WJ
[Ad] Endereço:1​Key Laboratory of Biogeography and Bioresource in Arid Land, Xinjiang Institute of Ecology and Geography, Chinese Academy of Sciences, Ürumqi 830011, PR China.
[Ti] Título:Bacillus tamaricis sp. nov., an alkaliphilic bacterium isolated from a Tamarix cone soil.
[So] Source:Int J Syst Evol Microbiol;68(2):558-563, 2018 Feb.
[Is] ISSN:1466-5034
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:A Gram-stain-positive, alkaliphilic bacterium, designated EGI 80668 , was isolated from a Tamarix cone soil in Xinjiang, north-west China. Cells were facultatively anaerobic, terminal endospore-forming and motile by means of peritrichous flagella. Colonies were yellowish and the cells showed oxidase-negative and catalase-positive reactions. Strain EGI 80668 grew at pH 8.0-10.0 and with 0-10 % (w/v) NaCl (optimally at pH 9.0 and with 1-2 % NaCl) on marine agar 2216. The predominant menaquinone was MK-7. The major fatty acids were anteiso-C17 : 0 and anteiso-C15 : 0. The cellular polar lipids contained diphosphatidylglycerol, phosphatidylglycerol, phosphatidylethanolamine, four unknown phospholipids and one unknown aminophospholipid. The G+C content of the genomic DNA was 38.3 mol%. Phylogenetic analysis based on 16S rRNA gene sequences showed that strain EGI 80668 was affiliated to the genus Bacillus. The highest 16S rRNA gene sequence similarity between strain EGI 80668 and a member of the genus Bacillus was 96.83 % with Bacillus cellulosilyticus JCM 9156 . A polyphasic taxonomic study based on morphological, physiological, biochemical and phylogenetic data indicated that strain EGI 80668 represents a novel species of the genus Bacillus, for which the name Bacillus tamaricis sp. nov. (type strain EGI 80668 =KCTC 33703 =CGMCC 1.15917 ) is proposed.
[Mh] Termos MeSH primário: Bacillus/classificação
Filogenia
Microbiologia do Solo
Tamaricaceae/microbiologia
[Mh] Termos MeSH secundário: Bacillus/genética
Bacillus/isolamento & purificação
Técnicas de Tipagem Bacteriana
Composição de Bases
China
DNA Bacteriano/genética
Ácidos Graxos/química
Fosfolipídeos/química
Pigmentação
RNA Ribossômico 16S/genética
Análise de Sequência de DNA
Vitamina K 2/análogos & derivados
Vitamina K 2/química
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (DNA, Bacterial); 0 (Fatty Acids); 0 (Phospholipids); 0 (RNA, Ribosomal, 16S); 11032-49-8 (Vitamin K 2); 8427BML8NY (vitamin MK 7)
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180212
[Lr] Data última revisão:
180212
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180104
[St] Status:MEDLINE
[do] DOI:10.1099/ijsem.0.002543


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[PMID]:29205133
[Au] Autor:Osman G; Gao Y; Wang N; Mahmud O; Sun J; Zhang T; Zhan F; Zhang Z; Lou K
[Ad] Endereço:1​Institute of Microbiology, Xinjiang Academy of Agricultural Sciences, Urumqi 830091, PR China.
[Ti] Título:Pontibacter brevis sp. nov., isolated from rhizosphere soil of Tamarix ramosissima.
[So] Source:Int J Syst Evol Microbiol;68(1):81-86, 2018 Jan.
[Is] ISSN:1466-5034
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:A Gram-stain-negative, oval-shaped and light pink pigmented bacterium, designated XAAS-2 , was isolated from rhizosphere soil of Tamarix ramosissima. The sole respiratory quinone of the type strain XAAS-2 was MK-7, and the principal cellular fatty acids were summed feature 4 (iso-C17 : 1 I and/or anteiso-C17 : 1 B) and iso-C15 : 0. The major polar lipids were phosphatidylethanolamine and two unidentified lipids. 16S rRNA gene sequence analysis indicated that strain XAAS-2 belonged to the genus Pontibacter within the family Cytophagaceae with sequence similarities of 93.9-97.1 % to other type species of the genus Pontibacter and to Pontibacter xinjiangensis CCTCC AB 207200 as the closest neighbour. The DNA G+C content of strain XAAS-2 was 50.6 mol%. The level of DNA-DNA relatedness of XAAS-2 and P. xinjiangensis CCTCC AB 207200 was 47.5 % (sd=3.27). Phenotypic and genotypic data suggested that strain XAAS-2 represents a novel species of the genus Pontibacter, for which the name Pontibacterbrevis sp. nov. is proposed, with the type strain XAAS-2 (=CCTCC AB 2016135 =JCM 31443 ).
[Mh] Termos MeSH primário: Bacteroidetes/classificação
Rizosfera
Microbiologia do Solo
Tamaricaceae/microbiologia
[Mh] Termos MeSH secundário: Técnicas de Tipagem Bacteriana
Bacteroidetes/genética
Bacteroidetes/isolamento & purificação
Composição de Bases
China
DNA Bacteriano/genética
Ácidos Graxos/química
Hibridização de Ácido Nucleico
Fosfatidiletanolaminas/química
Filogenia
RNA Ribossômico 16S/genética
Análise de Sequência de DNA
Vitamina K 2/análogos & derivados
Vitamina K 2/química
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (DNA, Bacterial); 0 (Fatty Acids); 0 (Phosphatidylethanolamines); 0 (RNA, Ribosomal, 16S); 11032-49-8 (Vitamin K 2); 39382-08-6 (phosphatidylethanolamine); 8427BML8NY (vitamin MK 7)
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180208
[Lr] Data última revisão:
180208
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171206
[St] Status:MEDLINE
[do] DOI:10.1099/ijsem.0.002455


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[PMID]:28604335
[Au] Autor:Zhao GY; Zhao LY; Xia ZJ; Zhu JL; Liu D; Liu CY; Chen XL; Zhang YZ; Zhang XY; Dai MX
[Ad] Endereço:2​Shandong Provincial Key Laboratory of Plant Stress Research, Jinan 250014, PR China 1​College of Life Science, Shandong Normal University, Jinan 250014, PR China.
[Ti] Título:Salinicola tamaricis sp. nov., a heavy-metal-tolerant, endophytic bacterium isolated from the halophyte Tamarix chinensis Lour.
[So] Source:Int J Syst Evol Microbiol;67(6):1813-1819, 2017 Jun.
[Is] ISSN:1466-5034
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:A Gram-stain-negative, rod-shaped bacterium, strain F01T, was isolated from leaves of Tamarix chinensis Lour. The isolate grew optimally at 30 °C, at pH 7.0 and with 5.0 % (w/v) NaCl, and showed a high tolerance to manganese, lead, nickel, ferrous ions and copper ions. The major fatty acids were C18 : 1ω7c and C16 : 0, and the predominant respiratory quinone was Q-9. Polar lipids were dominated by diphosphatidylglycerol, phosphatidylethanolamine, phosphatidylglycerol, unidentified aminoglycolipids and phospholipids. The DNA G+C content was 65.8 %. Based on multilocus phylogenetic analysis, strain F01T belonged to the genus Salinicola, with highest 16S rRNA gene sequence similarity to Salinicola peritrichatus CGMCC 1.12381T (97.7 %). The level of DNA-DNA hybridization between strain F01T and closely related Salinicola strains was well below 70 %. According to the phenotypic, genetic and chemotaxonomic data, strain F01T is considered to represent a novel species in the genus Salinicola, for which the name Salinicola tamaricis sp. nov. is proposed. The type strain is F01T (=CCTCC AB 2015304T=KCTC 42855T).
[Mh] Termos MeSH primário: Halomonadaceae/classificação
Filogenia
Plantas Tolerantes a Sal/microbiologia
Tamaricaceae/microbiologia
[Mh] Termos MeSH secundário: Técnicas de Tipagem Bacteriana
Composição de Bases
China
DNA Bacteriano/genética
Ácidos Graxos/química
Halomonadaceae/genética
Halomonadaceae/isolamento & purificação
Metais
Hibridização de Ácido Nucleico
Fosfolipídeos/química
RNA Ribossômico 16S/genética
Análise de Sequência de DNA
Vitamina K 2/análogos & derivados
Vitamina K 2/química
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (DNA, Bacterial); 0 (Fatty Acids); 0 (Metals); 0 (Phospholipids); 0 (RNA, Ribosomal, 16S); 11032-49-8 (Vitamin K 2); 523-39-7 (menaquinone 9)
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170906
[Lr] Data última revisão:
170906
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170613
[St] Status:MEDLINE
[do] DOI:10.1099/ijsem.0.001868


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[PMID]:28578496
[Au] Autor:Zang D; Wang L; Zhang Y; Zhao H; Wang Y
[Ad] Endereço:State Key Laboratory of Forest Genetics and Tree Breeding, Northeast Forestry University, 26 Hexing Road, Harbin, 150040, China.
[Ti] Título:ThDof1.4 and ThZFP1 constitute a transcriptional regulatory cascade involved in salt or osmotic stress in Tamarix hispida.
[So] Source:Plant Mol Biol;94(4-5):495-507, 2017 Jul.
[Is] ISSN:1573-5028
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:Identification of the upstream regulators of a gene is important to characterize the transcriptional pathway and the function of the gene. Previously, we found that a zinc finger protein (ThZFP1) is involved in abiotic stress tolerance of Tamarix hispida. In the present study, we further investigated the transcriptional pathway of ThZFP1. Dof motifs are abundant in the ThZFP1 promoter; therefore, we used them to screen for transcriptional regulators of ThZFP1. A Dof protein, ThDof1.4, binds to the Dof motif specifically, and was hypothesized as the upstream regulator of ThZFP1. Further study showed that overexpression of ThDof1.4 in T. hispida activated the expression of GUS controlled by the ThZFP1 promoter. In T. hispida, transient overexpression of ThDof1.4 increased the transcripts of ThZFP1; conversely, transient RNAi-silencing of ThDof1.4 reduced the expression of ThZFP1. Chromatin immunoprecipitation indicated that ThDof1.4 binds to the ThZFP1 promoter. Additionally, ThDof1.4 and ThZFP1 share similar expression patterns in response to salt or drought stress. Furthermore, like ThZFP1, ThDof1.4 could increase the proline level and enhance ROS scavenging capability to improve salt and osmotic stress tolerance. Together, these results suggested that ThDof1.4 and ThZFP1 form a transcriptional regulatory cascade involved in abiotic stress resistance in T. hispida.
[Mh] Termos MeSH primário: Regulação da Expressão Gênica de Plantas/fisiologia
Pressão Osmótica/fisiologia
Proteínas de Plantas/metabolismo
Cloreto de Sódio/toxicidade
Tamaricaceae/metabolismo
[Mh] Termos MeSH secundário: Clonagem Molecular
Regulação Enzimológica da Expressão Gênica
Peroxidases/genética
Peroxidases/metabolismo
Proteínas de Plantas/genética
Regiões Promotoras Genéticas
Ligação Proteica
Superóxido Dismutase/genética
Superóxido Dismutase/metabolismo
Transcrição Genética
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Plant Proteins); 451W47IQ8X (Sodium Chloride); EC 1.11.1.- (Peroxidases); EC 1.15.1.1 (Superoxide Dismutase)
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170801
[Lr] Data última revisão:
170801
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170605
[St] Status:MEDLINE
[do] DOI:10.1007/s11103-017-0620-x


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[PMID]:28222350
[Au] Autor:Yang G; Yu L; Zhang K; Zhao Y; Guo Y; Gao C
[Ad] Endereço:Laboratory of Walnut Research Center, College of Forestry, Northwest A & F University, Yangling 712100, Shaanxi, China; State Key Laboratory of Tree Genetics and Breeding, Northeast Forestry University, 26 Hexing Road, 150040 Harbin, China.
[Ti] Título:A ThDREB gene from Tamarix hispida improved the salt and drought tolerance of transgenic tobacco and T. hispida.
[So] Source:Plant Physiol Biochem;113:187-197, 2017 Apr.
[Is] ISSN:1873-2690
[Cp] País de publicação:France
[La] Idioma:eng
[Ab] Resumo:Dehydration-responsive element-binding (DREB) transcription factors are important abiotic stress tolerance related genes, and some reports on the roles of DREB have primarily addressed herbal plants. To explore the abiotic stress tolerance role of DREB (ThDREB) from Tamarix hispida, a ThDREB gene with a complete ORF of 783 bp that encodes a 28.74 kDa protein with 260 amino acids, was isolated and functionally annotated. ThDREB expression was highly induced by NaCl, PEG, NaHCO and CdCl treatments, and the highest expression level (369.2-fold of control) was found for the roots that were under NaCl stress for 6 h. The tobacco plants that were transformed by ThDREB were conferred with higher germination rates, fresh weights and root lengths than the wild type (WT) tobacco plants under NaCl and mannitol treatments. The total chlorophyll content (tcc), superoxide dismutase (SOD) and peroxidase (POD) activities were also higher in the transgenic lines in comparison with the WT, and the malondialdehyde (MDA) and H O content, electrolyte leakage (EL) rate and ROS as tracked by staining were generated to a lesser degree in ThDREB transgenic plants than in the WT under NaCl and mannitol stress. Furthermore, the transient overexpression analysis of ThDREB in T. hispida also improved plant salt and drought tolerance in comparison with the empty vector-transformed lines. Our results indicated that ThDREB expression could effectively improve tolerance to salt and drought stress by enhancing the antioxidase activity that keeps the ROS at a low accumulation level and makes them easy to scavenge.
[Mh] Termos MeSH primário: Secas
Proteínas de Plantas/genética
Plantas Tolerantes a Sal/genética
Estresse Fisiológico/genética
Tamaricaceae/genética
Tabaco/genética
[Mh] Termos MeSH secundário: Arabidopsis/genética
Arabidopsis/fisiologia
Cloreto de Cádmio/farmacologia
Clorofila/metabolismo
Regulação da Expressão Gênica de Plantas/efeitos dos fármacos
Germinação/efeitos dos fármacos
Peróxido de Hidrogênio/metabolismo
Malondialdeído/metabolismo
Peroxidase/metabolismo
Filogenia
Proteínas de Plantas/biossíntese
Proteínas de Plantas/metabolismo
Plantas Geneticamente Modificadas
Polietilenoglicóis/farmacologia
Plantas Tolerantes a Sal/efeitos dos fármacos
Plantas Tolerantes a Sal/enzimologia
Plantas Tolerantes a Sal/metabolismo
Bicarbonato de Sódio/farmacologia
Cloreto de Sódio/farmacologia
Superóxido Dismutase/metabolismo
Tamaricaceae/efeitos dos fármacos
Tamaricaceae/enzimologia
Tamaricaceae/metabolismo
Tabaco/efeitos dos fármacos
Tabaco/enzimologia
Tabaco/metabolismo
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Plant Proteins); 1406-65-1 (Chlorophyll); 30IQX730WE (Polyethylene Glycol 6000); 30IQX730WE (Polyethylene Glycols); 451W47IQ8X (Sodium Chloride); 4Y8F71G49Q (Malondialdehyde); 8MDF5V39QO (Sodium Bicarbonate); BBX060AN9V (Hydrogen Peroxide); EC 1.11.1.7 (Peroxidase); EC 1.15.1.1 (Superoxide Dismutase); J6K4F9V3BA (Cadmium Chloride)
[Em] Mês de entrada:1707
[Cu] Atualização por classe:171116
[Lr] Data última revisão:
171116
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170222
[St] Status:MEDLINE


  6 / 222 MEDLINE  
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[PMID]:28154265
[Au] Autor:Ben Hmidene A; Hanaki M; Murakami K; Irie K; Isoda H; Shigemori H
[Ad] Endereço:Graduate School of Life and Environmental Sciences, University of Tsukuba.
[Ti] Título:Inhibitory Activities of Antioxidant Flavonoids from Tamarix gallica on Amyloid Aggregation Related to Alzheimer's and Type 2 Diabetes Diseases.
[So] Source:Biol Pharm Bull;40(2):238-241, 2017.
[Is] ISSN:1347-5215
[Cp] País de publicação:Japan
[La] Idioma:eng
[Ab] Resumo:The prevention of amyloid aggregation is promising for the treatment of age-related diseases such as Alzheimer's (AD) and type 2 diabetes (T2D). Ten antioxidant flavonoids isolated from the medicinal halophyte Tamarix gallica were tested for their amyloid aggregation inhibition potential. Glucuronosylated flavonoids show relatively strong inhibitory activity of Amyloid ß (Aß) and human islet amyloid polypeptide (hIAPP) aggregation compared to their aglycone analogs. Structure-activity relationship of the flavonoids suggests that the catechol moiety is important for amyloid aggregation inhibition, while the methylation of the carboxyl group in the glucuronide moiety and of the hydroxyl group in the aglycone flavonoids decreased it.
[Mh] Termos MeSH primário: Doença de Alzheimer/metabolismo
Amiloide/metabolismo
Antioxidantes/farmacologia
Diabetes Mellitus Tipo 2/metabolismo
Flavonoides/farmacologia
Tamaricaceae
[Mh] Termos MeSH secundário: Amiloide/antagonistas & inibidores
Antioxidantes/isolamento & purificação
Flavonoides/isolamento & purificação
Seres Humanos
Componentes Aéreos da Planta
Extratos Vegetais/isolamento & purificação
Extratos Vegetais/farmacologia
Agregação Patológica de Proteínas/metabolismo
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Amyloid); 0 (Antioxidants); 0 (Flavonoids); 0 (Plant Extracts)
[Em] Mês de entrada:1702
[Cu] Atualização por classe:170208
[Lr] Data última revisão:
170208
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170204
[St] Status:MEDLINE
[do] DOI:10.1248/bpb.b16-00801


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[PMID]:28075411
[Au] Autor:Yao Y; Jiang CS; Sun N; Li WQ; Niu Y; Han HQ; Miao ZH; Zhao XX; Zhao J; Li J
[Ad] Endereço:School of Basic Medical Science, Ningxia Medical University, Yinchuan 750004, China. 15909511703@163.com.
[Ti] Título:Tamaractam, a New Bioactive Lactam from Tamarix ramosissima, Induces Apoptosis in Rheumatoid Arthritis Fibroblast-Like Synoviocytes.
[So] Source:Molecules;22(1), 2017 Jan 10.
[Is] ISSN:1420-3049
[Cp] País de publicação:Switzerland
[La] Idioma:eng
[Ab] Resumo:Chemical investigation of Ledeb, a traditional herbal medicine used for rheumatoid arthritis (RA) treatment in northwest China, led to the discovery of a new phenolic aromatic rings substituted lactam, tamaractam ( ), together with the previously reported compounds - -feruloyl-3- -methyldopamine ( ) and - -feruloyl-3- -methyldopamine ( ). The structures of the compounds were determined by high resolution electrospray ionization mass spectroscopy (HRESIMS) and 1D and 2D-NMR experiments, as well as comparison with the literature data. The effects of the three compounds on the viability of RA fibroblast-like synoviocytes (RA-FLS) were assessed by 3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2- -tetrazolium bromide (MTT) assay. Pro-apoptosis effect of compound in RA-FLS was further investigated by terminal deoxynucleotidyl transferase-mediated dUTP nick-end labeling (TUNEL) assay, activated caspase-3/7 level assessment using luminescence assay, and sub-G1 fraction measurement using flow cytometry. It was found that these three compounds displayed variable proliferation inhibitory activity in RA-FLS, and compound exhibited the strongest effect. Compound could remarkably induce cellular apoptosis of RA-FLS, increase activated caspase-3/7 levels, and significantly increase sub-G1 fraction in the cell cycle. The results suggested that compound may inhibit the proliferation of RA-FLS through apoptosis-inducing effect, and these compounds may contribute to the anti-RA effect of .
[Mh] Termos MeSH primário: Apoptose/efeitos dos fármacos
Artrite Reumatoide/tratamento farmacológico
Desoxiepinefrina/química
Lactamas/química
[Mh] Termos MeSH secundário: Linhagem Celular
Proliferação Celular/efeitos dos fármacos
Desoxiepinefrina/análogos & derivados
Desoxiepinefrina/farmacologia
Fibroblastos/efeitos dos fármacos
Seres Humanos
Lactamas/isolamento & purificação
Lactamas/farmacologia
Medicina Tradicional Chinesa
Sinoviócitos/efeitos dos fármacos
Tamaricaceae/química
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Lactams); R7339QLN1C (Deoxyepinephrine)
[Em] Mês de entrada:1705
[Cu] Atualização por classe:170509
[Lr] Data última revisão:
170509
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170112
[St] Status:MEDLINE


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[PMID]:28061406
[Au] Autor:Hebi M; Farid O; Ajebli M; Eddouks M
[Ad] Endereço:Faculty of Sciences and Techniques Errachidia, Moulay Ismail University, BP 509, Boutalamine, 52000, Errachidia, Morocco.
[Ti] Título:Potent antihyperglycemic and hypoglycemic effect of Tamarix articulata Vahl. in normal and streptozotocin-induced diabetic rats.
[So] Source:Biomed Pharmacother;87:230-239, 2017 Mar.
[Is] ISSN:1950-6007
[Cp] País de publicação:France
[La] Idioma:eng
[Ab] Resumo:The purpose of this study was to investigate the effect of a single dose and daily oral administration for seven days of the aerial part aqueous extract (A.P.A.E) of Tamarix articulata Vahl. (T. articulata) (5mg/kg) on blood glucose levels in both normal and streptozotocin-induced diabetic rats (STZ). Single oral administration of T. articulata A.P.A.E reduced blood glucose levels 6h after administration in normal rats (p<0.0001) and STZ diabetic rats (p<0.001). Furthermore, blood glucose levels were decreased in both normal (p<0.05) and STZ diabetic rats (p<0.0001) after seven days of treatment. Moreover, no significant changes in body weight in normal and STZ rats were shown. According to the oral glucose tolerance test, the aqueous extract of T. articulata (5mg/kg) was shown to prevent significantly the increase on blood glucose levels in both normal and diabetic treated rats 30min, 60min and 120min after glucose administration when compared to the control group. Additionally, histopathological analysis revealed the beneficial effect of T. articulata on pancreas and liver. Finally, the antioxydant activity of the aqueous extract of Tamarix articulata was evaluated by the method of trapping of free radical 2,2-diphenyl-1 picrylhydrazyl (DPPH). Tamarix articulata revealed inhibitory concentrations of 50% of free radicals (IC50) of 203.15µg/ml. In contrast, the synthetic antioxidant butylhydroxytoluene (BHT) has showed an IC50 equal to 13.71µg/ml. In conclusion, this study demonstrates antihyperglycemic, hypoglycemic and antioxidant effects of T. articulata in severe diabetic state thus warrants further investigation on its major compounds as well as mechanistic studies.
[Mh] Termos MeSH primário: Glicemia/metabolismo
Diabetes Mellitus Experimental/tratamento farmacológico
Diabetes Mellitus Experimental/metabolismo
Hipoglicemiantes/uso terapêutico
Extratos Vegetais/uso terapêutico
Tamaricaceae
[Mh] Termos MeSH secundário: Animais
Glicemia/efeitos dos fármacos
Diabetes Mellitus Experimental/induzido quimicamente
Hipoglicemiantes/farmacologia
Masculino
Componentes Aéreos da Planta
Extratos Vegetais/isolamento & purificação
Extratos Vegetais/farmacologia
Ratos
Ratos Wistar
Estreptozocina
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Blood Glucose); 0 (Hypoglycemic Agents); 0 (Plant Extracts); 5W494URQ81 (Streptozocin)
[Em] Mês de entrada:1702
[Cu] Atualização por classe:170710
[Lr] Data última revisão:
170710
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170107
[St] Status:MEDLINE


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[PMID]:27838961
[Au] Autor:Ben Hmidene A; Smaoui A; Abdelly C; Isoda H; Shigemori H
[Ad] Endereço:a Graduate School of Life and Environmental Sciences , University of Tsukuba , Tsukuba , Japan.
[Ti] Título:Effect of O-methylated and glucuronosylated flavonoids from Tamarix gallica on α-glucosidase inhibitory activity: structure-activity relationship and synergistic potential.
[So] Source:Biosci Biotechnol Biochem;81(3):445-448, 2017 Mar.
[Is] ISSN:1347-6947
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:O-Methylated and glucuronosylated flavonoids were isolated from Tamarix gallica as α-glucosidase inhibitors. Structure-activity relationship of these flavonoids suggests that catechol moiety and glucuronic acid at C-3 are factors in the increase in α-glucosidase inhibitory activity. Furthermore, rhamnetin, tamarixetin, rhamnazin, KGlcA, KGlcA-Me, QGlcA, and QGlcA-Me exhibit synergistic potential when applied with a very low concentration of acarbose to α-glucosidase from rat intestine.
[Mh] Termos MeSH primário: Flavonoides/química
Flavonoides/farmacologia
Inibidores de Glicosídeo Hidrolases/farmacologia
Tamaricaceae/química
[Mh] Termos MeSH secundário: Relação Dose-Resposta a Droga
Inibidores de Glicosídeo Hidrolases/química
Estrutura Molecular
Relação Estrutura-Atividade
alfa-Glucosidases/metabolismo
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Flavonoids); 0 (Glycoside Hydrolase Inhibitors); EC 3.2.1.20 (alpha-Glucosidases)
[Em] Mês de entrada:1703
[Cu] Atualização por classe:170306
[Lr] Data última revisão:
170306
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161115
[St] Status:MEDLINE
[do] DOI:10.1080/09168451.2016.1254538


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[PMID]:27739879
[Au] Autor:Wilson H; Mycock D; Weiersbye IM
[Ad] Endereço:a Faculty of Science, School of Animal, Plant, and Environmental Sciences, University of the Witwatersrand , Johannesburg , South Africa.
[Ti] Título:The salt glands of Tamarix usneoides E. Mey. ex Bunge (South African Salt Cedar).
[So] Source:Int J Phytoremediation;19(6):587-595, 2017 Jun 03.
[Is] ISSN:1549-7879
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Tamarix usneoides is a halophyte tree endemic to south-western Africa. This species is known to excrete a range of ions from specialized glandular structures on its leaves. To understand the mechanisms involved in the transport, sequestration and excretion of ions by the glands, a study was performed on salt gland distribution and ultrastructure. The glands are vesiculated trichomes, comprised of eight cells viz. two basal collecting cells and six excretory cells, partially bounded by a secondary cell wall that could serve as an impermeable barrier, forcing excess ions to move from the apoplast of the surrounding tissue into the cytoplasm of the basal excretory cells. It was hypothesized that the ions are moved across the excretory cells in endocytotic vesicles that fuse with the plasmalemma or form junctional complexes, allowing ion movement from one excretory cell to the next. In the apical cell, the vesicles fuse with the plasmalemma, releasing the ions into the network of cell wall ingrowths which channel the ions to the outside surface of the cell. This study shows that there are distinct structural adaptations for the processing of ions for excretion, although the mechanism by which ions enter the cells still needs to be determined.
[Mh] Termos MeSH primário: Plantas Tolerantes a Sal/metabolismo
Plantas Tolerantes a Sal/ultraestrutura
Cloreto de Sódio/metabolismo
Tamaricaceae/metabolismo
Tamaricaceae/ultraestrutura
[Mh] Termos MeSH secundário: Biodegradação Ambiental
Microscopia Eletrônica de Varredura
Microscopia Eletrônica de Transmissão
Folhas de Planta/ultraestrutura
Caules de Planta/ultraestrutura
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
451W47IQ8X (Sodium Chloride)
[Em] Mês de entrada:1704
[Cu] Atualização por classe:170406
[Lr] Data última revisão:
170406
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161015
[St] Status:MEDLINE
[do] DOI:10.1080/15226514.2016.1244163



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