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Pesquisa : B01.650.940.800.575.912.250.200.399 [Categoria DeCS]
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  1 / 1513 MEDLINE  
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[PMID]:29370244
[Au] Autor:Kroll JL; Werchan CA; Rosenfield D; Ritz T
[Ad] Endereço:Southern Methodist University, Dallas, TX, United States of America.
[Ti] Título:Acute ingestion of beetroot juice increases exhaled nitric oxide in healthy individuals.
[So] Source:PLoS One;13(1):e0191030, 2018.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:BACKGROUND AND OBJECTIVE: Nitric oxide (NO) plays an important role in the airways' innate immune response, and the fraction of exhaled NO at a flow rate of 50mL per second (FENO50) has been utilized to capture NO. Deficits in NO are linked to loss of bronchoprotective effects in airway challenges and predict symptoms of respiratory infection. While beetroot juice supplements have been proposed to enhance exercise performance by increasing dietary nitrate consumption, few studies have examined the impact of beetroot juice or nitrate supplementation on airway NO in contexts beyond an exercise challenge, which we know influences FENO50. METHODS: We therefore examined the influence of a beetroot juice supplement on FENO50 in healthy males and females (n = 38) during periods of rest and in normoxic conditions. FENO50, heart rate, blood pressure, and state affect were measured at baseline, 45 minutes, and 90 minutes following ingestion of 70ml beetroot juice (6.5 mmol nitrate). Identical procedures were followed with ingestion of 70ml of water on a control day. RESULTS: After beetroot consumption, average values of the natural log of FENO50 (lnFENO50) increased by 21.3% (Cohen's d = 1.54, p < .001) 45 minutes after consumption and by 20.3% (Cohen's d = 1.45, p < .001) 90 min after consumption. On the other hand, only very small increases in FENO50 were observed after consumption of the control liquid (less than 1% increase). A small subset (n = 4) of participants completed an extended protocol lasting over 3 hours, where elevated levels of FENO50 persisted. No significant changes in cardiovascular measures were observed with this small single dose of beetroot juice. CONCLUSION: As NO serves a key role in innate immunity, future research is needed to explore the potential clinical utility of beetroot and dietary nitrate to elevate FENO50 and prevent respiratory infection.
[Mh] Termos MeSH primário: Beta vulgaris/química
Testes Respiratórios
Óxido Nítrico/análise
Extratos Vegetais/farmacologia
[Mh] Termos MeSH secundário: Adolescente
Adulto
Sistema Cardiovascular/efeitos dos fármacos
Feminino
Seres Humanos
Masculino
Meia-Idade
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Plant Extracts); 31C4KY9ESH (Nitric Oxide)
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180309
[Lr] Data última revisão:
180309
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180126
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0191030


  2 / 1513 MEDLINE  
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[PMID]:28460054
[Au] Autor:Zhou N; Zhao S; Tian CY
[Ad] Endereço:State Key Laboratory of Desert and Oasis Ecology, Xinjiang Institute of Ecology and Geography, Chinese Academy of Sciences, Urumqi, China.
[Ti] Título:Effect of halotolerant rhizobacteria isolated from halophytes on the growth of sugar beet (Beta vulgaris L.) under salt stress.
[So] Source:FEMS Microbiol Lett;364(11), 2017 Jun 15.
[Is] ISSN:1574-6968
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Utilization of rhizobacteria that have associated with plant roots in harsh environments could be a feasible strategy to deal with limits to agricultural production caused by soil salinity. Halophytes occur naturally in high-salt environments, and their roots may be associated with promising microbial candidates for promoting growth and salt tolerance in crops. This study aimed to isolate efficient halotolerant plant-growth-promoting rhizobacterial strains from halophytes and evaluate their activity and effects on sugar beet (Beta vulgaris L.) growth under salinity stress. A total of 23 isolates were initially screened for their ability to secrete 1-aminocyclopropane-1-carboxylate deaminase (ACD) as well as other plant-growth-promoting characteristics and subsequently identified by sequencing the 16S rRNA gene. Three isolates, identified as Micrococcus yunnanensis, Planococcus rifietoensis and Variovorax paradoxus, enhanced salt stress tolerance remarkably in sugar beet, resulting in greater seed germination and plant biomass, higher photosynthetic capacity and lower stress-induced ethylene production at different NaCl concentrations (50-125 mM). These results demonstrate that salinity-adapted, ACD-producing bacteria isolated from halophytes could promote sugar beet growth under saline stress conditions.
[Mh] Termos MeSH primário: Alphaproteobacteria/classificação
Beta vulgaris/microbiologia
Raízes de Plantas/microbiologia
Plantas Tolerantes a Sal/microbiologia
Estresse Fisiológico
[Mh] Termos MeSH secundário: Alphaproteobacteria/genética
Alphaproteobacteria/isolamento & purificação
Beta vulgaris/crescimento & desenvolvimento
Biomassa
Carbono-Carbono Liases/metabolismo
Etilenos/metabolismo
Micrococcus/isolamento & purificação
Micrococcus/metabolismo
Bactérias Planococcus/isolamento & purificação
Bactérias Planococcus/metabolismo
RNA Ribossômico 16S/genética
Salinidade
Solo/química
Microbiologia do Solo
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Ethylenes); 0 (RNA, Ribosomal, 16S); 0 (Soil); 91GW059KN7 (ethylene); EC 3.5.99.7 (1-aminocyclopropane-1-carboxylate deaminase); EC 4.1.- (Carbon-Carbon Lyases)
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180108
[Lr] Data última revisão:
180108
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170502
[St] Status:MEDLINE
[do] DOI:10.1093/femsle/fnx091


  3 / 1513 MEDLINE  
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[PMID]:27777094
[Au] Autor:Thompson C; Vanhatalo A; Jell H; Fulford J; Carter J; Nyman L; Bailey SJ; Jones AM
[Ad] Endereço:Sport and Health Sciences, University of Exeter, Heavitree Road, Exeter, UK.
[Ti] Título:Dietary nitrate supplementation improves sprint and high-intensity intermittent running performance.
[So] Source:Nitric Oxide;61:55-61, 2016 Dec 30.
[Is] ISSN:1089-8611
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:The influence of dietary nitrate (NO ) supplementation on indices of maximal sprint and intermittent exercise performance is unclear. PURPOSE: To investigate the effects of NO supplementation on sprint running performance, and cognitive function and exercise performance during the sport-specific Yo-Yo Intermittent Recovery level 1 test (IR1). METHODS: In a double-blind, randomized, crossover study, 36 male team-sport players received NO -rich (BR; 70 mL·day ; 6.4 mmol of NO ), and NO -depleted (PL; 70 mL·day ; 0.04 mmol NO ) beetroot juice for 5 days. On day 5 of supplementation, subjects completed a series of maximal 20-m sprints followed by the Yo-Yo IR1. Cognitive tasks were completed prior to, during and immediately following the Yo-Yo IR1. RESULTS: BR improved sprint split times relative to PL at 20 m (1.2%; BR 3.98 ± 0.18 vs. PL 4.03 ± 0.19 s; P < 0.05), 10 m (1.6%; BR 2.53 ± 0.12 vs. PL 2.57 ± 0.19 s; P < 0.05) and 5 m (2.3%; BR 1.73 ± 0.09 vs. PL 1.77 ± 0.09 s; P < 0.05). The distance covered in the Yo-Yo IR1 test improved by 3.9% (BR 1422 ± 502 vs. PL 1369 ± 505 m; P < 0.05). The reaction time to the cognitive tasks was shorter in BR (615 ± 98 ms) than PL (645 ± 120 ms; P < 0.05) at rest but not during the Yo-Yo IR1. There was no difference in response accuracy. CONCLUSIONS: Dietary NO supplementation enhances maximal sprint and high-intensity intermittent running performance in competitive team sport players. Our findings suggest that NO supplementation has the potential to improve performance in single-sprint or multiple-sprint (team) sports.
[Mh] Termos MeSH primário: Desempenho Atlético/fisiologia
Nitratos
Corrida/fisiologia
[Mh] Termos MeSH secundário: Adulto
Beta vulgaris
Pressão Sanguínea/efeitos dos fármacos
Estudos Cross-Over
Suplementos Nutricionais
Método Duplo-Cego
Sucos de Frutas e Vegetais
Seres Humanos
Masculino
Nitratos/administração & dosagem
Nitratos/farmacologia
Nitritos/sangue
Teste de Stroop
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE; RANDOMIZED CONTROLLED TRIAL
[Nm] Nome de substância:
0 (Nitrates); 0 (Nitrites)
[Em] Mês de entrada:1712
[Cu] Atualização por classe:171229
[Lr] Data última revisão:
171229
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161026
[St] Status:MEDLINE


  4 / 1513 MEDLINE  
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[PMID]:29065114
[Au] Autor:Vaghefi N; Kikkert JR; Bolton MD; Hanson LE; Secor GA; Nelson SC; Pethybridge SJ
[Ad] Endereço:School of Integrative Plant Science, Plant Pathology & Plant-Microbe Biology Section, Cornell University, Geneva, New York, United States of America.
[Ti] Título:Global genotype flow in Cercospora beticola populations confirmed through genotyping-by-sequencing.
[So] Source:PLoS One;12(10):e0186488, 2017.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Genotyping-by-sequencing (GBS) was conducted on 333 Cercospora isolates collected from Beta vulgaris (sugar beet, table beet and swiss chard) in the USA and Europe. Cercospora beticola was confirmed as the species predominantly isolated from leaves with Cercospora leaf spot (CLS) symptoms. However, C. cf. flagellaris also was detected at a frequency of 3% in two table beet fields in New York. Resolution of the spatial structure and identification of clonal lineages in C. beticola populations using genome-wide single nucleotide polymorphisms (SNPs) obtained from GBS was compared to genotyping using microsatellites. Varying distance thresholds (bitwise distance = 0, 1.854599 × 10-4, and 1.298 × 10-3) were used for delineation of clonal lineages in C. beticola populations. Results supported previous reports of long distance dispersal of C. beticola through genotype flow. The GBS-SNP data set provided higher resolution in discriminating clonal lineages; however, genotype identification was impacted by filtering parameters and the distance threshold at which the multi-locus genotypes (MLGs) were contracted to multi-locus lineages. The type of marker or different filtering strategies did not impact estimates of population differentiation and structure. Results emphasize the importance of robust filtering strategies and designation of distance thresholds for delineating clonal lineages in population genomics analyses that depend on individual assignment and identification of clonal lineages. Detection of recurrent clonal lineages shared between the USA and Europe, even in the relaxed-filtered SNP data set and with a conservative distance threshold for contraction of MLGs, provided strong evidence for global genotype flow in C. beticola populations. The implications of intercontinental migration in C. beticola populations for CLS management are discussed.
[Mh] Termos MeSH primário: Ascomicetos/genética
Genótipo
[Mh] Termos MeSH secundário: Beta vulgaris/microbiologia
Repetições de Microssatélites/genética
Polimorfismo de Nucleotídeo Único
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1711
[Cu] Atualização por classe:171113
[Lr] Data última revisão:
171113
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171025
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0186488


  5 / 1513 MEDLINE  
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[PMID]:29036205
[Au] Autor:Liu JY; Fan HY; Wang Y; Zhang YL; Li DW; Yu JL; Han CG
[Ad] Endereço:State Key Laboratory for Agro-Biotechnology and Ministry of Agriculture Key Laboratory for Plant Pathology, China Agricultural University, Beijing, P. R. China.
[Ti] Título:Characterization of microRNAs of Beta macrocarpa and their responses to Beet necrotic yellow vein virus infection.
[So] Source:PLoS One;12(10):e0186500, 2017.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Plant microRNAs (miRNAs) are a class of non-coding RNAs that play important roles in plant development, defense, and symptom development. Here, 547 known miRNAs representing 129 miRNA families, and 282 potential novel miRNAs were identified in Beta macrocarpa using small RNA deep sequencing. A phylogenetic analysis was performed, and 8 Beta lineage-specific miRNAs were identified. Through a differential expression analysis, miRNAs associated with Beet necrotic yellow vein virus (BNYVV) infection were identified and confirmed using a microarray analysis and stem-loop RT-qPCR. In total, 103 known miRNAs representing 38 miRNA families, and 45 potential novel miRNAs were differentially regulated, with at least a two-fold change, in BNYVV-infected plants compared with that of the mock-inoculated control. Targets of these differentially expressed miRNAs were also predicted by degradome sequencing. These differentially expressed miRNAs were involved in hormone biosynthesis and signal transduction pathways, and enhanced axillary bud development and plant defenses. This work is the first to describe miRNAs of the plant genus Beta and may offer a reference for miRNA research in other species in the genus. It provides valuable information on the pathogenicity mechanisms of BNYVV.
[Mh] Termos MeSH primário: Beta vulgaris/genética
Beta vulgaris/virologia
MicroRNAs/genética
Doenças das Plantas/virologia
Vírus de Plantas/fisiologia
[Mh] Termos MeSH secundário: Beta vulgaris/citologia
Beta vulgaris/metabolismo
Regulação da Expressão Gênica de Plantas
Sequenciamento de Nucleotídeos em Larga Escala
Filogenia
Reguladores de Crescimento de Planta/biossíntese
Folhas de Planta/virologia
Análise de Sequência de RNA
Transdução de Sinais
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (MicroRNAs); 0 (Plant Growth Regulators)
[Em] Mês de entrada:1711
[Cu] Atualização por classe:171106
[Lr] Data última revisão:
171106
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171017
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0186500


  6 / 1513 MEDLINE  
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[PMID]:28786999
[Au] Autor:Sunil M; Hariharan N; Dixit S; Choudhary B; Srinivasan S
[Ad] Endereço:Institute of Bioinformatics and Applied Biotechnology, Bangalore, Karnataka, India.
[Ti] Título:Differential genomic arrangements in Caryophyllales through deep transcriptome sequencing of A. hypochondriacus.
[So] Source:PLoS One;12(8):e0180528, 2017.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Genome duplication event in edible dicots under the orders Rosid and Asterid, common during the oligocene period, is missing for species under the order Caryophyllales. Despite this, grain amaranths not only survived this period but display many desirable traits missing in species under rosids and asterids. For example, grain amaranths display traits like C4 photosynthesis, high-lysine seeds, high-yield, drought resistance, tolerance to infection and resilience to stress. It is, therefore, of interest to look for minor genome rearrangements with potential functional implications that are unique to grain amaranths. Here, by deep sequencing and assembly of 16 transcriptomes (86.8 billion bases) we have interrogated differential genome rearrangement unique to Amaranthus hypochondriacus with potential links to these phenotypes. We have predicted 125,581 non-redundant transcripts including 44,529 protein coding transcripts identified based on homology to known proteins and 13,529 predicted as novel/amaranth specific coding transcripts. Of the protein coding de novo assembled transcripts, we have identified 1810 chimeric transcripts. More than 30% and 19% of the gene pairs within the chimeric transcripts are found within the same loci in the genomes of A. hypochondriacus and Beta vulgaris respectively and are considered real positives. Interestingly, one of the chimeric transcripts comprises two important genes, namely DHDPS1, a key enzyme implicated in the biosynthesis of lysine, and alpha-glucosidase, an enzyme involved in sucrose catabolism, in close proximity to each other separated by a distance of 612 bases in the genome of A. hypochondriacus in a convergent configuration. We have experimentally validated that transcripts of these two genes are also overlapping in the 3' UTR with their expression negatively correlated from bud to mature seed, suggesting a potential link between the high seed lysine trait and unique genome organization.
[Mh] Termos MeSH primário: Amaranthus/genética
Amaranthus/metabolismo
Genoma de Planta
Transcriptoma
[Mh] Termos MeSH secundário: Beta vulgaris/genética
Beta vulgaris/metabolismo
Análise por Conglomerados
Biologia Computacional
Fusão Gênica
Homologia de Genes
Loci Gênicos
Sequenciamento de Nucleotídeos em Larga Escala
Lisina/metabolismo
Fenótipo
Proteínas de Plantas/genética
Proteínas de Plantas/metabolismo
Sementes/genética
Sementes/metabolismo
Homologia de Sequência
alfa-Glucosidases/genética
alfa-Glucosidases/metabolismo
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Plant Proteins); EC 3.2.1.20 (alpha-Glucosidases); K3Z4F929H6 (Lysine)
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171004
[Lr] Data última revisão:
171004
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170809
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0180528


  7 / 1513 MEDLINE  
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[PMID]:28624090
[Au] Autor:Nistor OV; Seremet Ceclu L; Andronoiu DG; Rudi L; Botez E
[Ad] Endereço:Food Science and Engineering Faculty "Dunarea de Jos" University of Galati, 111 Domneasca Street, 800201, Romania.
[Ti] Título:Influence of different drying methods on the physicochemical properties of red beetroot (Beta vulgaris L. var. Cylindra).
[So] Source:Food Chem;236:59-67, 2017 Dec 01.
[Is] ISSN:0308-8146
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:There is an increased interest in preserving fruits and vegetables by drying. The novelty of this study consists in the combination of the following three drying methods: free convection (at 50, 60, and 70°C), forced convection at 40°C and 315W microwave power. The aim of this study was to investigate the effects of the drying conditions on red beetroot (Beta vulgaris L.) in terms of betalain variance, and polyphenol, microstructure changes (SEM). A strong thermal shock, provided by convection at 60° followed by microwave wattage 315W/9min, leads to a better preservation of bioactive compounds content (0.631±0.0042mg/g of betacyanin and 0.795±0.0019mg/g betaxanthin) when compared to convection at 50, 60 and 70°C. The results showed that combined drying methods led to a significant preservation of the phytochemical content as compared to the traditional methods.
[Mh] Termos MeSH primário: Beta vulgaris/química
Manipulação de Alimentos/métodos
[Mh] Termos MeSH secundário: Betacianinas
Betalaínas
Temperatura Alta
Polifenóis
Verduras
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Betacyanins); 0 (Polyphenols); 37279-84-8 (Betalains)
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170808
[Lr] Data última revisão:
170808
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170619
[St] Status:MEDLINE


  8 / 1513 MEDLINE  
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[PMID]:28601776
[Au] Autor:Terboven C; Ramm P; Herrmann C
[Ad] Endereço:Leibniz Institute for Agricultural Engineering and Bioeconomy e.V. (ATB), Department of Bioengineering, Max-Eyth-Allee 100, 14469 Potsdam, Germany.
[Ti] Título:Demand-driven biogas production from sugar beet silage in a novel fixed bed disc reactor under mesophilic and thermophilic conditions.
[So] Source:Bioresour Technol;241:582-592, 2017 Oct.
[Is] ISSN:1873-2976
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:A newly developed fixed bed disc reactor (FBDR) which combines biofilm formation on biofilm carriers and reactor agitation in one single system was assessed for its applicability to demand-driven biogas production by variable feeding of sugar beet silage. Five different feeding patterns were studied at an organic loading of 4g L d under mesophilic and thermophilic conditions. High methane yields of 449-462L kg were reached. Feeding variable punctual loadings caused immediate response with 1.2- to 3.5-fold increase in biogas production rates within 15min. Although variable feeding did not induce process instability, a temporary decrease in pH-value and methane concentration below 40% occurred. Thermophilic temperature was advantageous as it resulted in a more rapid, higher methane production and less pronounced decrease in methane content after feeding. The FBDR was demonstrated to be well-suited for flexible biogas production, but further research and comparison with traditional reactor systems are required.
[Mh] Termos MeSH primário: Beta vulgaris
Biocombustíveis
Silagem
[Mh] Termos MeSH secundário: Anaerobiose
Reatores Biológicos
Metano
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Biofuels); OP0UW79H66 (Methane)
[Em] Mês de entrada:1711
[Cu] Atualização por classe:171106
[Lr] Data última revisão:
171106
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170612
[St] Status:MEDLINE


  9 / 1513 MEDLINE  
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[PMID]:28570910
[Au] Autor:Venugopal K; Ahmad H; Manikandan E; Thanigai Arul K; Kavitha K; Moodley MK; Rajagopal K; Balabhaskar R; Bhaskar M
[Ad] Endereço:Dept of Biotechnology, Vels University, Chennai -600117, Tamil Nadu, India. Electronic address: venuapcas@gmail.com.
[Ti] Título:The impact of anticancer activity upon Beta vulgaris extract mediated biosynthesized silver nanoparticles (ag-NPs) against human breast (MCF-7), lung (A549) and pharynx (Hep-2) cancer cell lines.
[So] Source:J Photochem Photobiol B;173:99-107, 2017 Aug.
[Is] ISSN:1873-2682
[Cp] País de publicação:Switzerland
[La] Idioma:eng
[Ab] Resumo:The present study tried for a phyto-synthetic method of producing silver nanoparticles (Ag-NPs) with size controlled as and eco-friendly route that can lead to their advanced production with decorative tranquil morphology. By inducing temperature fluctuation of the reaction mixture from 25 to 80°C the plasmon resonance band raised slowly which had an ultimate effect on size and shape of Ag-NPs as shown by UV-visible spectroscopy and TEM results. The biosynthesized nanoparticles showed good cytotoxic impact against MCF-7, A549 and Hep2 cells compared to normal cell lines. Compared to control plates, the percentage of cell growth inhibition was found to be high with as concentrations of Ag-NPs becomes more as determined by MTT assay. The AO/EtBr staining observations demonstrated that the mechanism of cell death induced by Ag-NPs was due to apoptosis in cancer cells. These present results propose that the silver nanoparticles (Ag-NPs) may be utilized as anticancer agents for the treatment of various cancer types. However, there is a need for study of in vivo examination of these nanoparticles to find their role and mechanism inside human body. Further, studies we plan to do biomarker fabrication from the green synthesized plant extract nanoparticles like silver, gold and copper nanoparticles with optimized shape and sizes and their enhancement of these noble nanoparticles.
[Mh] Termos MeSH primário: Antineoplásicos/farmacologia
Apoptose/efeitos dos fármacos
Beta vulgaris/química
Nanopartículas Metálicas/química
Extratos Vegetais/química
Prata/química
[Mh] Termos MeSH secundário: Células A549
Antineoplásicos/síntese química
Antineoplásicos/química
Beta vulgaris/metabolismo
Linhagem Celular Tumoral
Química Verde
Seres Humanos
Células MCF-7
Microscopia Eletrônica de Transmissão
Microscopia de Fluorescência
Tamanho da Partícula
Espectrofotometria Ultravioleta
Espectroscopia de Infravermelho com Transformada de Fourier
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Antineoplastic Agents); 0 (Plant Extracts); 3M4G523W1G (Silver)
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171006
[Lr] Data última revisão:
171006
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170602
[St] Status:MEDLINE


  10 / 1513 MEDLINE  
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[PMID]:28570816
[Au] Autor:Vissers A; Kiskini A; Hilgers R; Marinea M; Wierenga PA; Gruppen H; Vincken JP
[Ad] Endereço:Laboratory of Food Chemistry, Wageningen University & Research , Bornse Weilanden 9, 6708 WG Wageningen, The Netherlands.
[Ti] Título:Enzymatic Browning in Sugar Beet Leaves (Beta vulgaris L.): Influence of Caffeic Acid Derivatives, Oxidative Coupling, and Coupled Oxidation.
[So] Source:J Agric Food Chem;65(24):4911-4920, 2017 Jun 21.
[Is] ISSN:1520-5118
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Sugar beet (Beta vulgaris L.) leaves of 8 month (8 ) plants showed more enzymatic browning than those of 3 month (3 ). Total phenolic content increased from 4.6 to 9.4 mg/g FW in 3 and 8 , respectively, quantitated by reverse-phase-ultrahigh-performance liquid chromatography-ultraviolet-mass spectrometry (RP-UHPLC-UV-MS). The PPO activity was 6.7 times higher in extracts from 8 than from 3 leaves. Substrate content increased from 0.53 to 2.45 mg/g FW in 3 and 8 , respectively, of which caffeic acid glycosyl esters were most important, increasing 10-fold with age. Caffeic acid glycosides and vitexin derivatives were no substrates. In 3 and 8 nonsubstrate-to-substrate ratios were 8:1 and 3:1, respectively. A model system showed browning at 3:1 ratio due to formation of products with extensive conjugated systems through oxidative coupling and coupled oxidation. The 8:1 ratio did not turn brown as oxidative coupling occurred without much coupled oxidation. We postulate that differences in nonsubstrate-to-substrate ratio and therewith extent of coupled oxidation explain browning.
[Mh] Termos MeSH primário: Beta vulgaris/enzimologia
Ácidos Cafeicos/metabolismo
Catecol Oxidase/metabolismo
Extratos Vegetais/metabolismo
Proteínas de Plantas/metabolismo
[Mh] Termos MeSH secundário: Beta vulgaris/química
Ácidos Cafeicos/química
Catecol Oxidase/química
Cromatografia Líquida de Alta Pressão
Espectrometria de Massas
Acoplamento Oxidativo
Fenóis/química
Fenóis/metabolismo
Extratos Vegetais/química
Folhas de Planta/química
Folhas de Planta/enzimologia
Proteínas de Plantas/química
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Caffeic Acids); 0 (Phenols); 0 (Plant Extracts); 0 (Plant Proteins); EC 1.10.3.1 (Catechol Oxidase); U2S3A33KVM (caffeic acid)
[Em] Mês de entrada:1707
[Cu] Atualização por classe:170703
[Lr] Data última revisão:
170703
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170602
[St] Status:MEDLINE
[do] DOI:10.1021/acs.jafc.7b01897



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