Base de dados : MEDLINE
Pesquisa : B01.650.940.800.575.912.250.341.937.774.875 [Categoria DeCS]
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[PMID]:29272302
[Au] Autor:Zorenc Z; Veberic R; Slatnar A; Koron D; Miosic S; Chen MH; Haselmair-Gosch C; Halbwirth H; Mikulic-Petkovsek M
[Ad] Endereço:Department of Agronomy, Chair for Fruit, Wine and Vegetable Growing, Biotechnical Faculty, University of Ljubljana, Ljubljana, Slovenia.
[Ti] Título:A wild 'albino' bilberry (Vaccinium myrtillus L.) from Slovenia shows three bottlenecks in the anthocyanin pathway and significant differences in the expression of several regulatory genes compared to the common blue berry type.
[So] Source:PLoS One;12(12):e0190246, 2017.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Relative expressions of structural genes and a number of transcription factors of the anthocyanin pathway relevant in Vaccinium species, and related key enzyme activities were compared with the composition and content of metabolites in skins of ripe fruits of wild albino and blue bilberry (Vaccinium myrtillus) found in Slovenia. Compared to the common blue type, the albino variant had a 151-fold lower total anthocyanin and a 7-fold lower total phenolic content in their berry skin, which correlated with lower gene expression of flavonoid 3-O-glycosyltransferase (FGT; 33-fold), flavanone 3-hydroxylase (FHT; 18-fold), anthocyanidin synthase (ANS; 11-fold), chalcone synthase (CHS, 7.6-fold) and MYBPA1 transcription factor (22-fold). The expression of chalcone isomerase (CHI), dihydroflavonol 4-reductase (DFR), leucoanthocyanidin reductase (LAR), anthocyanidin reductase (ANR) and MYBC2 transcription factor was reduced only by a factor of 1.5-2 in the albino berry skins, while MYBR3 and flavonoid 3',5'-hydroxylase (F3'5'H) were increased to a similar extent. Expression of the SQUAMOSA class transcription factor TDR4, in contrast, was independent of the color type and does therefore not seem to be correlated with anthocyanin formation in this variant. At the level of enzymes, significantly lower FHT and DFR activities, but not of phenylalanine ammonia-lyase (PAL) and CHS/CHI, were observed in the fruit skins of albino bilberries. A strong increase in relative hydroxycinnamic acid derivative concentrations indicates the presence of an additional bottleneck in the general phenylpropanoid pathway at a so far unknown step between PAL and CHS.
[Mh] Termos MeSH primário: Antocianinas/metabolismo
Genes de Plantas
Genes Reguladores
Vaccinium myrtillus/metabolismo
[Mh] Termos MeSH secundário: Regulação da Expressão Gênica de Plantas
Fenóis/metabolismo
Eslovênia
Especificidade da Espécie
Vaccinium myrtillus/genética
[Pt] Tipo de publicação:COMPARATIVE STUDY; JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Anthocyanins); 0 (Phenols)
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180116
[Lr] Data última revisão:
180116
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171223
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0190246


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[PMID]:29182628
[Au] Autor:Kowalska K; Olejnik A; Szwajgier D; Olkowicz M
[Ad] Endereço:Department of Biotechnology and Food Microbiology, Poznan University of Life Sciences, Poznan, Poland.
[Ti] Título:Inhibitory activity of chokeberry, bilberry, raspberry and cranberry polyphenol-rich extract towards adipogenesis and oxidative stress in differentiated 3T3-L1 adipose cells.
[So] Source:PLoS One;12(11):e0188583, 2017.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Berries are a rich source of antioxidants and phytochemicals that have received considerable interest for their possible relations to human health. In this study, the anti-adipogenic effect of polyphenol-rich extract obtained from chokeberry Aronia melanocarpa (Michx.) Elliot, raspberry Rubus idaeus L., bilberry Vaccinium myrtillus L. and cranberry Vaccinium macrocarpon Aiton fruits and its underlying molecular mechanisms were investigated in differentiated 3T3-L1 adipose cells. Treatment with the extract (25-100 µg/mL) significantly decreased lipid accumulation and reactive oxygen species generation in adipocytes without showing cytotoxicity. Real-time PCR analysis revealed that the extract at a concentration of 100 µg/mL suppressed adipogenesis and lipogenesis via the down-regulation of PPARγ (67%), C/EBPα (72%), SREBP1 (62%), aP2 (24%), FAS (32%), LPL (40%), HSL (39%), and PLIN1 (32%) gene expression. Moreover, the extract significantly increased the expression of adiponectin (4.4-fold) and decreased leptin expression (90%) and respectively regulated the production of these adipokines in 3T3-L1 adipocytes. The obtained results suggest that the analyzed extract may be a promising source of bioactive compounds that support long-term weight maintenance and promote the effective management of obesity.
[Mh] Termos MeSH primário: Adipócitos/efeitos dos fármacos
Adipogenia/efeitos dos fármacos
Estresse Oxidativo/efeitos dos fármacos
Extratos Vegetais/farmacologia
Polifenóis/farmacologia
Rosaceae/química
Rubus/química
Vaccinium myrtillus/química
[Mh] Termos MeSH secundário: Células 3T3-L1
Adipócitos/metabolismo
Animais
Camundongos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Plant Extracts); 0 (Polyphenols)
[Em] Mês de entrada:1712
[Cu] Atualização por classe:171226
[Lr] Data última revisão:
171226
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171129
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0188583


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[PMID]:28865231
[Au] Autor:Matysek M; Mozel S; Szalak R; Zacharko-Siembida A; Obszanska K; Arciszewski MB
[Ad] Endereço:.
[Ti] Título:Effect of feeding with bilberry fruit on the expression pattern of αCaMKII in hippocampal neurons in normal and diabetic rats.
[So] Source:Pol J Vet Sci;20(2):313-319, 2017 Mar 01.
[Is] ISSN:1505-1773
[Cp] País de publicação:Germany
[La] Idioma:eng
[Ab] Resumo:αCaMKII, widely occurring in the central nervous system, plays a significant role in cognitive processes. It is well known that diabetes is a risk factor that may trigger brain atrophy, cognitive dysfunction and finally lead to memory loss. Antioxidants richly present in bilberry fruits are believed to have significant effects on diabetes-related brain dysfunctions mainly due to their abilities to modulate neurotransmitter release that lead to reduction of the negative impact of free radicals on cognitive processes. The aim of the present research was to immunohistochemically investigate the expression patterns of αCaMKII in hippocampal neurons from non-diabetic, diabetic and diabetic rats fed with an extract of bilberry fruit. The obtained results show that in comparison to the control group, in diabetic rats hippocampal neurons immunoreactive (ir) to αCaMKII were swollen and the lengths of the neuronal fibres were reduced. Further study shows that in diabetic rats fed with bilberry fruit, αCaMKII-positive nerve fibres were significantly longer when compared to the groups of diabetic and control rats. Additionally, we observed statistically significant changes in the average larger diameter of αCaMKII-ir hippocampal neurons between groups of diabetic rats (with vs. without supplement of bilberry fruit). The results of the present work suggest that antioxidants present in bilberry fruits influence the morphology of and possibly exhibit beneficial and neuroprotective effects on hippocampal neurons during diabetes. It is likely that changes in the appearance of αCaMKII-expressed hippocampal neurons may reflect the diabetes-evoked rise in Ca2+ level in the cerebral nerve terminals. The present research extends our knowledge of preventive mechanisms for cognitive dysfunctions occurring in the brain during diabetes.
[Mh] Termos MeSH primário: Proteína Quinase Tipo 2 Dependente de Cálcio-Calmodulina/metabolismo
Diabetes Mellitus Experimental/metabolismo
Frutas
Hipocampo/citologia
Extratos Vegetais/farmacologia
Vaccinium myrtillus
[Mh] Termos MeSH secundário: Animais
Antioxidantes/química
Antioxidantes/farmacologia
Proteína Quinase Tipo 2 Dependente de Cálcio-Calmodulina/genética
Dieta/veterinária
Regulação da Expressão Gênica/efeitos dos fármacos
Masculino
Neurônios/efeitos dos fármacos
Neurônios/patologia
Extratos Vegetais/química
Ratos
Ratos Wistar
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Antioxidants); 0 (Plant Extracts); EC 2.7.11.17 (Calcium-Calmodulin-Dependent Protein Kinase Type 2); EC 2.7.11.17 (Camk2a protein, rat)
[Em] Mês de entrada:1711
[Cu] Atualização por classe:171106
[Lr] Data última revisão:
171106
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170903
[St] Status:MEDLINE


  4 / 261 MEDLINE  
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[PMID]:28699753
[Au] Autor:Xiao T; Guo Z; Sun B; Zhao Y
[Ad] Endereço:Shenyang Pharmaceutical University , Shenyang 110016, China.
[Ti] Título:Identification of Anthocyanins from Four Kinds of Berries and Their Inhibition Activity to α-Glycosidase and Protein Tyrosine Phosphatase 1B by HPLC-FT-ICR MS/MS.
[So] Source:J Agric Food Chem;65(30):6211-6221, 2017 Aug 02.
[Is] ISSN:1520-5118
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:The polyphenolic profiles of four berries (blueberry, bilberry, mulberry, and cranberry) in China were investigated using Fourier transform-ion cyclotron resonance mass spectrometry (FT-ICR MS). Thirty-nine polyphenols including 26 anthocyanins, 9 flavonoids, and 4 phenolic acids were identified accurately. Cyanidin aglycones are common in four berries, and malvidin aglycones are the main compounds found in bilberry and cranberry. The anthocyanin level in blueberry are the highest with 739.6 ± 17.14 mg/g DW and presented the strongest antioxidant capacity in DPPH, ABTS, FRAP, and ORAC assay. In α-glycosidase, the inhibition activity was in the following order: mulberry > bilberry > blueberry > cranberry. For the PTP1B inhibition assay, blueberry demonstrated the highest inhibitory effect with IC 3.06 ± 0.02 µg/mL, followed by bilberry, mulberry, and cranberry. Molecular docking results showed that cyanidin aglycones had the highest inhibition activity to PTP1B.
[Mh] Termos MeSH primário: Antocianinas/química
Inibidores Enzimáticos/química
Frutas/química
Extratos Vegetais/química
Proteína Tirosina Fosfatase não Receptora Tipo 1/antagonistas & inibidores
[Mh] Termos MeSH secundário: Antocianinas/isolamento & purificação
Mirtilos Azuis (Planta)/química
Cromatografia Líquida de Alta Pressão
Inibidores Enzimáticos/isolamento & purificação
Inibidores de Glicosídeo Hidrolases/química
Inibidores de Glicosídeo Hidrolases/isolamento & purificação
Seres Humanos
Simulação de Acoplamento Molecular
Morus/química
Extratos Vegetais/isolamento & purificação
Proteína Tirosina Fosfatase não Receptora Tipo 1/química
Proteína Tirosina Fosfatase não Receptora Tipo 1/metabolismo
Espectrometria de Massas em Tandem
Vaccinium myrtillus/química
alfa-Glucosidases/química
alfa-Glucosidases/metabolismo
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Anthocyanins); 0 (Enzyme Inhibitors); 0 (Glycoside Hydrolase Inhibitors); 0 (Plant Extracts); EC 3.1.3.48 (PTPN1 protein, human); EC 3.1.3.48 (Protein Tyrosine Phosphatase, Non-Receptor Type 1); EC 3.2.1.20 (alpha-Glucosidases)
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170811
[Lr] Data última revisão:
170811
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170713
[St] Status:MEDLINE
[do] DOI:10.1021/acs.jafc.7b02550


  5 / 261 MEDLINE  
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[PMID]:28570634
[Au] Autor:Osada H; Okamoto T; Kawashima H; Toda E; Miyake S; Nagai N; Kobayashi S; Tsubota K; Ozawa Y
[Ad] Endereço:Laboratory of Retinal Cell Biology, Department of Ophthalmology, Keio University School of Medicine, Tokyo, Japan.
[Ti] Título:Neuroprotective effect of bilberry extract in a murine model of photo-stressed retina.
[So] Source:PLoS One;12(6):e0178627, 2017.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Excessive exposure to light promotes degenerative and blinding retinal diseases such as age-related macular degeneration and retinitis pigmentosa. However, the underlying mechanisms of photo-induced retinal degeneration are not fully understood, and a generalizable preventive intervention has not been proposed. Bilberry extract is an antioxidant-rich supplement that ameliorates ocular symptoms. However, its effects on photo-stressed retinas have not been clarified. In this study, we examined the neuroprotective effects of bilberry extract against photo-stress in murine retinas. Light-induced visual function impairment recorded by scotopic and phototopic electroretinograms showing respective rod and cone photoreceptor function was attenuated by oral administration of bilberry extract through a stomach tube in Balb/c mice (750 mg/kg body weight). Bilberry extract also suppressed photo-induced apoptosis in the photoreceptor cell layer and shortening of the outer segments of rod and cone photoreceptors. Levels of photo-induced reactive oxygen species (ROS), oxidative and endoplasmic reticulum (ER) stress markers, as measured by real-time reverse transcriptase polymerase chain reaction, were reduced by bilberry extract treatment. Reduction of ROS by N-acetyl-L-cysteine, a well-known antioxidant also suppressed ER stress. Immunohistochemical analysis of activating transcription factor 4 expression showed the presence of ER stress in the retina, and at least in part, in Müller glial cells. The photo-induced disruption of tight junctions in the retinal pigment epithelium was also attenuated by bilberry extract, repressing an oxidative stress marker, although ER stress markers were not repressed. Our results suggest that bilberry extract attenuates photo-induced apoptosis and visual dysfunction most likely, and at least in part, through ROS reduction, and subsequent ER stress attenuation in the retina. This study can help understand the mechanisms of photo-stress and contribute to developing a new, potentially useful therapeutic approach using bilberry extract for preventing retinal photo-damage.
[Mh] Termos MeSH primário: Modelos Animais
Extratos Vegetais/farmacologia
Retina/efeitos dos fármacos
Estresse Fisiológico
Vaccinium myrtillus/química
[Mh] Termos MeSH secundário: Acetilcisteína/administração & dosagem
Animais
Antioxidantes/administração & dosagem
Antioxidantes/farmacologia
Eletrorretinografia
Estresse do Retículo Endoplasmático/efeitos dos fármacos
Masculino
Camundongos
Camundongos Endogâmicos BALB C
Extratos Vegetais/administração & dosagem
Espécies Reativas de Oxigênio/metabolismo
Retina/metabolismo
Retina/fisiopatologia
Retina/efeitos da radiação
Epitélio Pigmentado da Retina/efeitos dos fármacos
Epitélio Pigmentado da Retina/efeitos da radiação
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Antioxidants); 0 (Plant Extracts); 0 (Reactive Oxygen Species); WYQ7N0BPYC (Acetylcysteine)
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170926
[Lr] Data última revisão:
170926
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170602
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0178627


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[PMID]:28374224
[Au] Autor:Koski TM; Kalpio M; Laaksonen T; Sirkiä PM; Kallio HP; Yang B; Linderborg KM; Klemola T
[Ad] Endereço:Section of Ecology, Department of Biology, University of Turku, 20014, Turku, FI, Finland. tmhkos@utu.fi.
[Ti] Título:Effects of Insect Herbivory on Bilberry Production and Removal of Berries by Frugivores.
[So] Source:J Chem Ecol;43(4):422-432, 2017 Apr.
[Is] ISSN:1573-1561
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:The evolutionary purpose of a fleshy fruit is to attract seed dispersers and get the seeds dispersed by frugivorous animals. For this reason, fruits should be highly rewarding to these mutualists. However, insect herbivory can alter plant reproductive success e.g. by decreasing fruit yield or affecting the attractiveness of the fruits to mutualistic seed dispersers. Under natural conditions, we tested the effects of experimental larval-defoliation on berry ripening and consumption of a non-cultivated dwarf shrub, the bilberry (Vaccinium myrtillus L.), which produces animal-dispersed berries with high sugar and anthocyanin concentration. Bilberry ramets with high fruit yield were most likely to have their berries foraged, indicating that frugivores made foraging choices based on the abundance of berries. Moreover, the probability for berries being foraged was the lowest for non-defoliated ramets that grew adjacent to larval-defoliated ramets, even though larval-defoliation did not affect the biochemical composition (total concentrations of anthocyanins, sugars and organic acids) or the probability of ripening of berries. We hypothesise that the lower probability for berries being foraged in these ramets may be a consequence of rhizome- or volatile-mediated communication between ramets, resulting in a priming effect of the herbivore defence and lower attractiveness of the non-defoliated ramets.
[Mh] Termos MeSH primário: Antocianinas/análise
Frutas/crescimento & desenvolvimento
Herbivoria
Mariposas/fisiologia
Vaccinium myrtillus/química
Vaccinium myrtillus/fisiologia
[Mh] Termos MeSH secundário: Animais
Antocianinas/química
Antocianinas/metabolismo
Cromatografia Gasosa
Cromatografia Líquida de Alta Pressão
Larva/fisiologia
Dispersão de Sementes
Sementes/fisiologia
Vaccinium myrtillus/metabolismo
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Anthocyanins)
[Em] Mês de entrada:1707
[Cu] Atualização por classe:171027
[Lr] Data última revisão:
171027
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170405
[St] Status:MEDLINE
[do] DOI:10.1007/s10886-017-0838-8


  7 / 261 MEDLINE  
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[PMID]:28317746
[Au] Autor:Xu Y; Fan M; Zhou S; Wang L; Qian H; Zhang H; Qi X
[Ad] Endereço:State Key Laboratory of Food Science and Technology, School of Food Science and Technology, Jiangnan University, Wuxi 214122, China.
[Ti] Título:Effect of Vaccinium bracteatum Thunb. leaf pigment on the thermal, pasting, and textural properties and microstructure characterization of rice starch.
[So] Source:Food Chem;228:435-440, 2017 Aug 01.
[Is] ISSN:0308-8146
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:In this study, the thermal, pasting and gel textural properties of japonica rice starch (JRS) and glutinous rice starch (GRS) fortified with Vaccinium bracteatum Thunb. leaf pigment (VBTLP) were investigated. The results showed that VBTLP facilitated the gelatinization of JRS and GRS with earlier onsets of onset temperature (T ), peak temperature (T ), conclusion temperature (T ), and lower values of gelatinization enthalpy (ΔH ), and retrogradation enthalpy (ΔH ), as the VBTLP level increased. For JRS, VBTLP increased the peak viscosity and breakdown, reduced the final viscosity and setback, but for GRS it increased the peak viscosity, final viscosity, breakdown and setback. VBTLP also reduced the hardness and adhesiveness of the JRS gel. The values of lightness (L ) for JRS and GRS with VBTLP decreased by 47.60 and 49.56%, respectively. Scanning electron microscopy (SEM) revealed that VBTLP caused looser matrices in dried JRS and GRS gels which had lower crystallinities compared with the control.
[Mh] Termos MeSH primário: Microscopia Eletrônica de Varredura/métodos
Oryza/química
Folhas de Planta/química
Amido/química
Vaccinium myrtillus/química
[Mh] Termos MeSH secundário: Viscosidade
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
9005-25-8 (Starch)
[Em] Mês de entrada:1705
[Cu] Atualização por classe:170501
[Lr] Data última revisão:
170501
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170321
[St] Status:MEDLINE


  8 / 261 MEDLINE  
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[PMID]:27855899
[Au] Autor:Tian Y; Liimatainen J; Alanne AL; Lindstedt A; Liu P; Sinkkonen J; Kallio H; Yang B
[Ad] Endereço:Food Chemistry and Food Development, Department of Biochemistry, University of Turku, FI-20014 Turku, Finland.
[Ti] Título:Phenolic compounds extracted by acidic aqueous ethanol from berries and leaves of different berry plants.
[So] Source:Food Chem;220:266-281, 2017 Apr 01.
[Is] ISSN:0308-8146
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Phenolic compounds of berries and leaves of thirteen various plant species were extracted with aqueous ethanol and analyzed with UPLC-DAD-ESI-MS, HPLC-DAD, and NMR. The total content of phenolics was consistently higher in leaves than in berries (25-7856 vs. 28-711mg/100g fresh weight). Sea buckthorn leaves were richest in phenolic compounds (7856mg/100g f.w.) with ellagitannins as the dominant compound class. Sea buckthorn berries contained mostly isorhamnetin glycosides, whereas quercetin glycosides were typically abundant in most samples investigated. Anthocyanins formed the dominating group of phenolics in most dark-colored berries but phenolic acid derivatives were equally abundant in saskatoon and chokeberry berries. Caffeoylquinic acids constituted 80% of the total phenolic content (1664mg/100g f.w.) in bilberry leaves. B-type procyanidins and caffeoylquinic acids were the major phenolic compounds in hawthorn and rowanberry, respectively. Use of leaves of some species with prunasin, tyramine and ß-p-arbutin, may be limited in food applications.
[Mh] Termos MeSH primário: Frutas/química
Fenóis/análise
Extratos Vegetais/análise
Folhas de Planta/química
[Mh] Termos MeSH secundário: Antocianinas/análise
Cromatografia Líquida de Alta Pressão
Crataegus/química
Glicosídeos/análise
Hippophae/química
Hidroxibenzoatos/análise
Espectroscopia de Ressonância Magnética
Prunus/química
Quercetina/análogos & derivados
Quercetina/análise
Ribes/química
Sorbus/química
Vaccinium macrocarpon/química
Vaccinium myrtillus/química
Vaccinium vitis-Idaea/química
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Anthocyanins); 0 (Glycosides); 0 (Hydroxybenzoates); 0 (Phenols); 0 (Plant Extracts); 07X3IB4R4Z (3-methylquercetin); 29656-58-4 (phenolic acid); 9IKM0I5T1E (Quercetin)
[Em] Mês de entrada:1701
[Cu] Atualização por classe:170110
[Lr] Data última revisão:
170110
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161119
[St] Status:MEDLINE


  9 / 261 MEDLINE  
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[PMID]:27838575
[Au] Autor:Dabbou S; Gai F; Renna M; Rotolo L; Dabbou S; Lussiana C; Kovitvadhi A; Brugiapaglia A; De Marco M; Helal AN; Zoccarato I; Gasco L
[Ad] Endereço:Department of Agricultural, Forest and Food Sciences, University of Turin, largo Paolo Braccini 2, 10095 Grugliasco, Turin, Italy; Laboratory of Bioresources, Integrative Biology and Valorisation, Higher Institute of Biotechnology of Monastir, av. Tahar Hadded, BP 74, 5000, Monastir, Tunisia. Electr
[Ti] Título:Inclusion of bilberry pomace in rabbit diets: Effects on carcass characteristics and meat quality.
[So] Source:Meat Sci;124:77-83, 2017 Feb.
[Is] ISSN:1873-4138
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:A trial was performed to evaluate bilberry pomace (BP) as alternative source of nutrients for rabbits. One hundred and forty-four Grimaud weaned rabbits were divided into 4 groups of 36 animals each and fed ad libitum with a basal diet (BP0) tested against three assay diets developed by substituting 50, 100 and 150g/kg of the BP0 diet with BP (BP5, BP10 and BP15 diets, respectively). Carcass characteristics of rabbits were not affected by treatment, with the exception of liver weight. Dietary inclusion of BP did not affect proximate composition and oxidative status of longissimus thoracis et lumborum muscle. Dietary BP significantly ameliorated, in the same muscle, the nutritional quality and health properties of fat. Consumer acceptance of cooked rabbit meat was not significantly affected by treatment. In conclusion, BP can be included in rabbit diets to improve the lipid composition of meat, without adverse effects on carcass characteristics, other physico-chemical properties, oxidative status and meat sensorial traits.
[Mh] Termos MeSH primário: Ração Animal/análise
Dieta/veterinária
Carne
Vaccinium myrtillus
[Mh] Termos MeSH secundário: Adulto
Fenômenos Fisiológicos da Nutrição Animal
Animais
Comportamento do Consumidor
Culinária
Ácidos Graxos/análise
Ácidos Graxos Ômega-3/análise
Feminino
Qualidade dos Alimentos
Seres Humanos
Metabolismo dos Lipídeos
Masculino
Meia-Idade
Músculo Esquelético/química
Coelhos
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Fatty Acids); 0 (Fatty Acids, Omega-3)
[Em] Mês de entrada:1705
[Cu] Atualização por classe:170518
[Lr] Data última revisão:
170518
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161114
[St] Status:MEDLINE


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[PMID]:27714928
[Au] Autor:Veljkovic M; Pavlovic DR; Stojiljkovic N; Ilic S; Jovanovic I; Poklar Ulrih N; Rakic V; Velickovic L; Sokolovic D
[Ad] Endereço:Department of Physiology, University of Nis, Faculty of Medicine, Bulevar Dr Zoran Djindjic 81, Nis, Serbia.
[Ti] Título:Bilberry: Chemical Profiling, in Vitro and in Vivo Antioxidant Activity and Nephroprotective Effect against Gentamicin Toxicity in Rats.
[So] Source:Phytother Res;31(1):115-123, 2017 Jan.
[Is] ISSN:1099-1573
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:We assessed possible protective effect of bilberry diet in rat model of nephrotoxicity. In vivo and in vitro antioxidant activity and chemical profiling of this functional food was performed. With aid of HPLC-DAD and spectrophotometric method, 15 individual anthocyanins were quantified alongside total tannin, phenylpropanoid, and anthocyanin content. The study was conducted on four groups of rats: control, treated with only gentamicin, treated with only bilberry, and treated with both gentamicin and bilberry. Kidney function was evaluated by tracking urea and creatinine. Morphology of renal tissue and its changes were recorded pathohistologically and quantified morphometrically. Bilberry (100 mg/kg daily) showed strong nephroprotective effect against gentamicin toxicity in rats (as shown through MDA, AOPP, and catalase levels). In conclusion, the demonstrated protective activity of bilberry extract matched well with the assessed in vivo and in vitro antioxidant activity as well as with its polyphenolic content, particularly with high anthocyanin levels. Copyright © 2016 John Wiley & Sons, Ltd.
[Mh] Termos MeSH primário: Antibacterianos/efeitos adversos
Cromatografia Líquida de Alta Pressão/métodos
Gentamicinas/efeitos adversos
Extratos Vegetais/química
Vaccinium myrtillus/química
[Mh] Termos MeSH secundário: Animais
Antibacterianos/administração & dosagem
Antioxidantes
Gentamicinas/administração & dosagem
Masculino
Extratos Vegetais/farmacologia
Ratos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Anti-Bacterial Agents); 0 (Antioxidants); 0 (Gentamicins); 0 (Plant Extracts)
[Em] Mês de entrada:1704
[Cu] Atualização por classe:170817
[Lr] Data última revisão:
170817
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161008
[St] Status:MEDLINE
[do] DOI:10.1002/ptr.5738



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