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  1 / 102 MEDLINE  
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[PMID]:28692127
[Au] Autor:Cabral JC; Baldoni AB; Tonini H; Azevedo VCR; Giustina LD; Tiago AV; Rossi AAB
[Ad] Endereço:Laboratório de Genética Vegetal e Biologia Molecular, Faculdade de Ciências Biológicas e Agrárias, Centro de Tecnologia da Amazônia Meridional, Universidade do Estado de Mato Grosso, Campus de Alta Floresta, Alta Floresta, MT, Brasil.
[Ti] Título:Diversity and genetic structure of the native Brazil nut tree (Bertholletia excelsa Bonpl.) population.
[So] Source:Genet Mol Res;16(3), 2017 Jul 06.
[Is] ISSN:1676-5680
[Cp] País de publicação:Brazil
[La] Idioma:eng
[Ab] Resumo:The present study was carried out in a native Brazil nut tree population (Bertholletia excelsa Bonpl., Lecythidaceae) to assess its genetic diversity and structure. Ten microsatellite markers were used to genotype 198 adult trees (B. excelsa). The population presented high genetic diversity and inbreeding absence rates. The empirical Bayesian method showed three distinct groups in the structure of this population. Molecular analysis of variance showed 98% variability within groups, and 2% between groups. The genetic divergence (F ) indicated little difference between groups; thus, suggesting efficient gene flow between the analyzed B. excelsa adult trees.
[Mh] Termos MeSH primário: Bertholletia/genética
Genótipo
Polimorfismo Genético
[Mh] Termos MeSH secundário: Teorema de Bayes
Fluxo Gênico
Endogamia
Repetições de Microssatélites
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171019
[Lr] Data última revisão:
171019
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170711
[St] Status:MEDLINE
[do] DOI:10.4238/gmr16039702


  2 / 102 MEDLINE  
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Corrêa, Benedito
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[PMID]:27817100
[Au] Autor:Ferranti LS; Correa B; Fungaro MH; Iamanaka BT; Massi FP; Phippen CB; Frisvad JC; Taniwaki MH
[Ad] Endereço:Instituto de Tecnologia de Alimentos - ITAL, C.P. 139, Campinas, SP, CEP 13070-178, Brazil. issaferranti@uol.com.br.
[Ti] Título:Occurrence and fumonisin B producing potential of Aspergillus section Nigri in Brazil nuts.
[So] Source:Mycotoxin Res;33(1):49-58, 2017 Feb.
[Is] ISSN:1867-1632
[Cp] País de publicação:Germany
[La] Idioma:eng
[Ab] Resumo:Bertholletia excelsa is the tree that produces Brazil nuts which have vast economic importance in the Amazon region and as an export commodity. The aim of this study was to assess the presence of Aspergillus section Nigri in Brazil nut samples at different stages of its production chain and to verify the toxigenic potential for fumonisin B (FB ) production of these isolates along with the presence of this mycotoxin in Brazil nut samples. The fungal infection ranged from 0 to 80% at the different stages of the harvest and processing chain and the water activity of the nuts from 0.273 to 0.994. A total of 1052 A. section Nigri strains were isolated from Brazil nuts and 200 strains were tested for their ability to produce FB : 41 strains (20.5%) were FB producers with concentrations ranging from 0.09 to 37.25 mg/kg; 2 strains (1%) showed traces of FB , less than the detection limit (0.08 mg/kg); and 157 (78.5%) were not FB producers. Although several samples showed high contamination by A. section Nigri, no sample was contaminated by FB .
[Mh] Termos MeSH primário: Aspergillus/isolamento & purificação
Bertholletia/química
Bertholletia/microbiologia
Carcinógenos Ambientais/análise
Fumonisinas/análise
[Mh] Termos MeSH secundário: Aspergillus/crescimento & desenvolvimento
Aspergillus/metabolismo
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Carcinogens, Environmental); 0 (Fumonisins); 116355-84-1 (fumonisin B2)
[Em] Mês de entrada:1704
[Cu] Atualização por classe:171110
[Lr] Data última revisão:
171110
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161107
[St] Status:MEDLINE
[do] DOI:10.1007/s12550-016-0262-x


  3 / 102 MEDLINE  
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[PMID]:28000476
[Au] Autor:Vidal Martins M; Montezano de Carvalho IM; Magalhães Caetano MM; Lopes Toledo RC; Avelar Xavier A; De Queiroz JH
[Ad] Endereço:Departamento de Bioquímica e Biologia Molecular. Universidade Federal de Viçosa. Universidade Federal do Oeste da Bahia, Campus Barreiras. marcosvidalmartins@yahoo.com.br.
[Ti] Título:Neuroprotective effect of Sapucaia nuts (Lecythis pisonis)on rats fed with high-fat diet.
[So] Source:Nutr Hosp;33(6):1424-1429, 2016 Nov 29.
[Is] ISSN:1699-5198
[Cp] País de publicação:Spain
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Lecythis pisonis Cambess is commonly known as "castanha de sapucaia" in Brazil. Chemical composition studies revealed that this nut is an excellent source of anti-oxidant minerals and of essential lipids. OBJECTIVE: The aim of the present study is to assess the anti-oxidant and anti-inflammatory effect of Lecythis pisonis Cambess on the brain tissue of Wistar rats. MATERIAL AND METHODS: The animals were divided in four experimental groups (n = 6), total of forty-eight rats. Treatments included the standard diet (AIN-93G) and high-fat food, supplemented with Sapucaianut from 14 to 28 days. The gene expression markers TNF-α, NFkB, ZnSOD and HSP-72 were defined through reverse transcriptase polymerase chain reaction (rtPCR). The anti-oxidant effect was assessed through the thiobarbituric acid-reactive substances (TBARS) and the measurement of the activity performed by superoxide dismutase enzymes. RESULTS: Accordingly, the gene expression of the inflammatory markers NFkB (p65) and TNF-αwas lower in rats fed on diets supplemented with "sapucaia", and they presented significant difference in the Tukey test (p < 0.05). The heat-shock HSP-72 protein and the ZnSOD enzyme raised the gene expression and showed significant statistical difference (p < 0.05) in both groups fed on Sapucaia nut-based diet. CONCLUSION: Thus, the nutritional properties of the Sapucaia nuts perform important neuroprotective activities because they modulated the anti-oxidant activity and the brain tissue inflammatory process in the assessed animals.
[Mh] Termos MeSH primário: Bertholletia/química
Gorduras na Dieta/efeitos adversos
Lecythidaceae/química
Fármacos Neuroprotetores/farmacologia
[Mh] Termos MeSH secundário: Animais
Antioxidantes/metabolismo
Química Encefálica/efeitos dos fármacos
Inflamação/prevenção & controle
Masculino
Estresse Oxidativo/efeitos dos fármacos
Ratos
Ratos Wistar
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Antioxidants); 0 (Dietary Fats); 0 (Neuroprotective Agents)
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171023
[Lr] Data última revisão:
171023
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161222
[St] Status:MEDLINE
[do] DOI:10.20960/nh.805


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[PMID]:27923410
[Au] Autor:Hu Y; McIntosh GH; Le Leu RK; Somashekar R; Meng XQ; Gopalsamy G; Bambaca L; McKinnon RA; Young GP
[Ad] Endereço:1Flinders Centre for Innovation in Cancer,Flinders University,Adelaide,South Australia,Australia.
[Ti] Título:Supplementation with Brazil nuts and green tea extract regulates targeted biomarkers related to colorectal cancer risk in humans.
[So] Source:Br J Nutr;116(11):1901-1911, 2016 Dec.
[Is] ISSN:1475-2662
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Se and green tea have been shown in epidemiological, observational and preclinical studies to be inversely related to the risk of developing colorectal cancer (CRC). However, there are limited studies to evaluate their regulatory effects on genes/proteins that relate to CRC oncogenesis in human subjects, such as selenoproteins, WNT signalling pathway, inflammation and methylation. This study examined the effects of supplementation of Se using Brazil nuts and green tea extract (GTE) capsules, alone and in combination, on targeted biomarkers. In total, thirty-two volunteers (>50 years of age) with plasma Se≤1·36 µmol/l were randomised to one of three treatment groups: nine to Se (approximately 48 µg/d) as six Brazil nuts, eleven to four GTE capsules (800 mg (-)-epigallocatechin-3-gallate) and twelve to a combination of Brazil nuts and GTE. Blood and rectal biopsies were obtained before and after each intervention. Plasma Se levels, rectal selenoprotein P (SePP) and ß-catenin mRNA increased significantly in subjects consuming Brazil nuts alone or in combination, whereas rectal DNA methyltransferase (DNMT1) and NF-κB mRNA were reduced significantly in subjects consuming GTE alone or in combination. None of the interventions significantly affected rectal acetylated histone H3 or Ki-67 expression at the protein level or plasma C-reactive protein. Effects of the combination of Brazil nuts and GTE did not differ from what would be expected from either agent alone. In conclusion, supplementation of Brazil nuts and/or GTE regulates targeted biomarkers related to CRC oncogenesis, specifically genes associated with selenoproteins (SePP), WNT signalling (ß-catenin), inflammation (NF-κB) and methylation (DNMT1). Their combination does not appear to provide additional effects compared with either agent alone.
[Mh] Termos MeSH primário: Anticarcinógenos/uso terapêutico
Bertholletia
Camellia sinensis/química
Neoplasias Colorretais/prevenção & controle
Suplementos Nutricionais
Nozes
Extratos Vegetais/uso terapêutico
[Mh] Termos MeSH secundário: Idoso
Bertholletia/efeitos adversos
Bertholletia/química
Biomarcadores Tumorais/sangue
Biomarcadores Tumorais/metabolismo
Neoplasias Colorretais/epidemiologia
Neoplasias Colorretais/metabolismo
Neoplasias Colorretais/patologia
Suplementos Nutricionais/efeitos adversos
Estudos de Viabilidade
Feminino
Manipulação de Alimentos
Alimento Funcional/efeitos adversos
Seres Humanos
Mucosa Intestinal/metabolismo
Mucosa Intestinal/patologia
Masculino
Meia-Idade
Nozes/efeitos adversos
Nozes/química
Extratos Vegetais/efeitos adversos
Extratos Vegetais/química
Folhas de Planta/química
Reto/metabolismo
Reto/patologia
Risco
Selênio/administração & dosagem
Selênio/efeitos adversos
Selênio/sangue
Selênio/uso terapêutico
Austrália do Sul/epidemiologia
[Pt] Tipo de publicação:COMPARATIVE STUDY; JOURNAL ARTICLE; RANDOMIZED CONTROLLED TRIAL
[Nm] Nome de substância:
0 (Anticarcinogenic Agents); 0 (Biomarkers, Tumor); 0 (Plant Extracts); H6241UJ22B (Selenium)
[Em] Mês de entrada:1705
[Cu] Atualização por classe:170515
[Lr] Data última revisão:
170515
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161208
[St] Status:MEDLINE
[do] DOI:10.1017/S0007114516003937


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[PMID]:27378377
[Au] Autor:Awaad A; Moustafa AY
[Ad] Endereço:Department of Zoology, Faculty of Science, Sohag University, Sohag 82524, Egypt. Electronic address: aawaad@science.sohag.edu.eg.
[Ti] Título:Immunotoxicity of skin acid secretion produced by the sea slug Berthellina citrina in mice spleen: Histological and Immunohistochemical study.
[So] Source:Acta Histochem;118(6):596-605, 2016 Jul.
[Is] ISSN:1618-0372
[Cp] País de publicação:Germany
[La] Idioma:eng
[Ab] Resumo:Acid secretion containing sulfuric and hydrochloric acids is a fascinating defensive phenomenon within many groups of marine organisms. This study aimed to investigate the mice spleen histology and immunotoxicity using skin acid secretion (SAS) of the sea slug Berthellina citrina after oral administration. The spleen showed atrophy in the white pulp, decrease in the splenocytes density, megakaryocytes cytoplasmic degeneration as well as inflammatory cells infiltrations. The white and red pulp splenocytes number decreased time-dependently in the treated spleens. Additionally, the size of the megakaryocytes increased as compared with the control. The administration with SAS increased the number of the IgA(+) cells aggregation in the splenic red pulp. Furthermore, after 7days of the administration, large number of dispersed IgA(+) cells were distributed in splenic parenchyma. The IgA(+) cells numbers increased time-dependently as compared with those in the control. The aggregation sizes and number of the F4/80(+) cell in the splenic red pulp were increased. Furthermore the F4/80(+) cells numbers increased time-dependently as compared with those in the control. The UEAI(+) cells were found as free cells but not in aggregations in the control splenic red pulp. Contradictory to the number of IgA(+) cells and F4/80(+) cells the number of the UEAI(+) cells decreased time-dependently after administration with SAS. Hematologically, abnormal numbers of WBCs different cells were observed after administration with SAS. This study provides new insight about the toxicity of a marine extract may be used in natural products industry or medical applications.
[Mh] Termos MeSH primário: Ácidos/metabolismo
Bertholletia/química
Imunotoxinas/isolamento & purificação
Leucócitos/citologia
Pele/efeitos dos fármacos
Pele/metabolismo
Baço/efeitos dos fármacos
Baço/metabolismo
[Mh] Termos MeSH secundário: Animais
Imuno-Histoquímica/métodos
Camundongos
Pele/patologia
Baço/patologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Acids); 0 (Immunotoxins)
[Em] Mês de entrada:1701
[Cu] Atualização por classe:170917
[Lr] Data última revisão:
170917
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160706
[St] Status:MEDLINE


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Corrêa, Benedito
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[PMID]:27224419
[Au] Autor:Baquião AC; Rodriges AG; Lopes EL; Tralamazza SM; Zorzete P; Correa B
[Ad] Endereço:1 Departamento de Microbiologia, Instituto de Ciências Biomédicas, Universidade de São Paulo , São Paulo, Brazil .
[Ti] Título:Expression of Genes by Aflatoxigenic and Nonaflatoxigenic Strains of Aspergillus flavus Isolated from Brazil Nuts.
[So] Source:Foodborne Pathog Dis;13(8):434-40, 2016 08.
[Is] ISSN:1556-7125
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:The aims of the present study were to monitor the production of aflatoxin B1 (AFB1) and mycelial growth, and to evaluate the expression of genes directly and indirectly involved in the biosynthesis of aflatoxins by Aspergillus flavus isolated from Brazil nuts. Six previously identified A. flavus strains were grown on coconut agar at 25°C for up to 10 days. Mycotoxins were separated by high-performance liquid chromatography and fungal growth was measured daily using the diametric mycelial growth rate. Transcriptional analysis was performed by real-time polymerase chain reaction (PCR) after 2 and 7 d of incubation using specific primers (aflR, aflD, aflP, lipase, metalloprotease, and LaeA). Three (50%) of the six A. flavus isolates produced AFB1 (ICB-1, ICB-12, and ICB-54) and three (50%) were not aflatoxigenic (ICB-141, ICB-161, and ICB-198). Aflatoxin production was observed from d 2 of incubation (1.5 ng/g for ICB-54) and increased gradually with time of incubation until d 10 (15,803.6 ng/g for ICB-54). Almost all A. flavus isolates exhibited a similar gene expression pattern after 2 d of incubation (p > 0.10). After 7 d of incubation, the LaeA (p < 0.05) and metalloprotease (p < 0.05) genes were the most expressed by nonaflatoxigenic strains, whereas aflatoxigenic isolates exhibited higher expression of the aflR (p < 0.05) and aflD genes (p < 0.05). Our results suggest that the expression of aflR and aflD is correlated with aflatoxin production in A. flavus and that overexpression of aflR could affect the transcriptional and aflatoxigenic pattern (ICB-54). Elucidation of the molecular mechanisms that regulate the secondary metabolism of toxigenic fungi may permit the rational silencing of the genes involved and consequently the programmed inhibition of aflatoxin production. Knowledge of the conditions, under which aflatoxin genes are expressed, should contribute to the development of innovative and more cost-effective strategies to reduce and prevent aflatoxin contamination in Brazil nuts.
[Mh] Termos MeSH primário: Aflatoxinas/biossíntese
Aflatoxinas/genética
Aspergillus flavus/genética
Bertholletia/microbiologia
[Mh] Termos MeSH secundário: Aflatoxina B1/biossíntese
Aflatoxina B1/genética
Aspergillus flavus/crescimento & desenvolvimento
Contaminação de Alimentos
Expressão Gênica
Genes Fúngicos
Micélio/crescimento & desenvolvimento
Reação em Cadeia da Polimerase em Tempo Real
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Aflatoxins); 9N2N2Y55MH (Aflatoxin B1)
[Em] Mês de entrada:1708
[Cu] Atualização por classe:171120
[Lr] Data última revisão:
171120
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160526
[St] Status:MEDLINE
[do] DOI:10.1089/fpd.2015.2111


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[PMID]:26661784
[Au] Autor:Cardoso BR; Busse AL; Hare DJ; Cominetti C; Horst MA; McColl G; Magaldi RM; Jacob-Filho W; Cozzolino SM
[Ad] Endereço:Faculty of Pharmaceutical Sciences, Department of Food and Experimental Nutrition, University of São Paulo, São Paulo, Brazil and The Florey Institute of Neuroscience and Mental Health, The University of Melbourne, 30 Royal Parade, Parkville, Victoria 3052, Australia. barbara.rita@florey.edu.au bari
[Ti] Título:Pro198Leu polymorphism affects the selenium status and GPx activity in response to Brazil nut intake.
[So] Source:Food Funct;7(2):825-33, 2016 Feb.
[Is] ISSN:2042-650X
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Selenoproteins play important roles in antioxidant mechanisms, and are thus hypothesised to have some involvement in the pathology of certain types of dementia. Mild cognitive impairment (MCI) and Alzheimer's disease (AD) are both thought to involve impaired biological activity of certain selenoproteins. Previously, supplementation with a selenium-rich Brazil nut (Bertholletia excelsa) has shown potential in reducing cognitive decline in MCI patients, and could prove to be a safe and effective nutritional approach early in the disease process to slow decline. Here, we have conducted a pilot study that examined the effects of a range of single nucleotide polymorphisms (SNPs) in genes encoding the selenoproteins glutathione peroxidase (GPX1) and selenoprotein P (SEPP) in response to selenium supplementation via dietary Brazil nuts, including selenium status, oxidative stress parameters and GPX1 and SEPP gene expression. Our data suggest that GPX1 Pro198Leu rs1050450 genotypes may differentially affect the selenium status and GPx activity. Moreover, rs7579 and rs3877899 SNPs in SEPP gene, as well as GPX1 rs1050450 genotypes can influence the expression of GPX1 and SEPP mRNA in response to Brazil nuts intake. This small study gives cause for larger investigations into the role of these SNPs in both the selenium status and response to selenium dietary intake, especially in chronic degenerative conditions like MCI and AD.
[Mh] Termos MeSH primário: Bertholletia/metabolismo
Disfunção Cognitiva/genética
Disfunção Cognitiva/metabolismo
Glutationa Peroxidase/genética
Nozes/metabolismo
Polimorfismo de Nucleotídeo Único
Selênio/metabolismo
[Mh] Termos MeSH secundário: Idoso
Bertholletia/química
Brasil
Feminino
Genótipo
Glutationa Peroxidase/metabolismo
Seres Humanos
Masculino
Meia-Idade
Nozes/química
Projetos Piloto
Selenoproteína P/genética
Selenoproteína P/metabolismo
[Pt] Tipo de publicação:JOURNAL ARTICLE; RANDOMIZED CONTROLLED TRIAL
[Nm] Nome de substância:
0 (Selenoprotein P); EC 1.11.1.- (glutathione peroxidase GPX1); EC 1.11.1.9 (Glutathione Peroxidase); H6241UJ22B (Selenium)
[Em] Mês de entrada:1612
[Cu] Atualização por classe:161230
[Lr] Data última revisão:
161230
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:151215
[St] Status:MEDLINE
[do] DOI:10.1039/c5fo01270h


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[PMID]:26653751
[Au] Autor:Momcilovic B; Prejac J; Visnjevic V; Brundic S; Skalny AA; Mimica N
[Ad] Endereço:Institut za istrazivanje i razvoj odrzivih ekosustava (IRES), Srebrnjak 59, 10000 Zagreb, Croatia. Electronic address: berislav.momcilovic@gmail.com.
[Ti] Título:High hair selenium mother to fetus transfer after the Brazil nuts consumption.
[So] Source:J Trace Elem Med Biol;33:110-3, 2016 Jan.
[Is] ISSN:1878-3252
[Cp] País de publicação:Germany
[La] Idioma:eng
[Ab] Resumo:Lactating mother and her two month old healthy daughter (APGAR 10) gave their scalp hair for a multielement profile analysis; 25 elements were analyzed with the ICP MS. Mother's hair was divided into 5cm long segment proximal to the scull (Young), and the distal segment further up to the hair tip (Old). One centimeter of hair records one month of the metabolic activity of the bioelements in the body. Mother's Young hair and daughters hair have 2.70 and 9.74µgg(-1)Se, a distinctly higher Se concentrations than the Old hair of 0.87µgg(-1). The adequate hair Se concentrations in Croatia women population vary from 0.08 to 0.63µgg(-1); values below or above that range indicate deficiency or excess, respectively. Dietary recall revealed that during the last trimester of pregnancy and over a period of a week, the mother has consumed 135g of Brazil nuts (Bertholletia excelsa) (BN); BN is an exceptionally rich Se dietary source. The amount of Se in BN varies and one week consumption of 135g of BN may result in Se daily intake of 367 to 492µgg(-1)day(-1) over a period of seven consecutive days, and what is about or exceeds the Upper Limit of daily selenium intake of 400µg(-1)g(-1). The excessively high infant hair Se mirrored a natural high mother to fetus transplacental transfer of bio elements in the last trimester of pregnancy. The potential toxicological risks of such a high Se transfer remains to be elucidated.
[Mh] Termos MeSH primário: Bertholletia/química
Feto/metabolismo
Cabelo/química
Selênio/metabolismo
[Mh] Termos MeSH secundário: Adulto
Feminino
Seres Humanos
Lactação
Mães
Gravidez
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
H6241UJ22B (Selenium)
[Em] Mês de entrada:1609
[Cu] Atualização por classe:151215
[Lr] Data última revisão:
151215
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:151215
[St] Status:MEDLINE


  9 / 102 MEDLINE  
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Silva, José Carlos Costa Baptista
[PMID]:26572874
[Au] Autor:Ferrari CK; Percário S; Silva JC; da Silva Torres EA
[Ti] Título:An apple plus a Brazil nut a day keeps the doctors away: antioxidant capacity of foods and their health benefits.
[So] Source:Curr Pharm Des;22(2):189-95, 2016.
[Is] ISSN:1873-4286
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:Antioxidant-rich foods scavenge free radicals and other reactive species, decreasing the risk of different non-communicable chronic diseases. The objective of this study was to review the content of total antioxidant capacity of commonly foods comparing with experimental data and to explore the health benefits due to foods with moderate to high TAC. The TAC was analytically measured using the "Total Antioxidant Capacity" (NX2332) test from Randox® (UK) by spectrometry at 600 nm. Brazil nut (Bertholletia excelsa), "guaraná" (Paullinia cupana Kunth) powder, ready to drink boiled coffee (Coffea arabica L.), and milk chocolate (made from seeds of Theobroma cacao) had the highest TAC values, followed by collard greens (Brassica oleracea L.), beets (Beta vulgaris L.), apples (Malus domestica Borkh.), bananas (Musa paradisiaca), common beans (Phaseolus vulgaris), oranges (Citrus sinensis (L.) Osbeck), onions (Allium cepa L.), and lettuce (Lactuca sativa L.). Other foods also showed antioxidant capacity. The binomial antioxidant capacity of foods and health was extensively discussed according to science literature. Based on the high TAC content of Brazil nuts, guaraná, coffee, chocolate, collard greens, apples, beets, beans, oranges, onions and other foods, their regular dietary intake is strongly recommended to reduce the risk of chronic non-communicable diseases.
[Mh] Termos MeSH primário: Bertholletia
Malus
Fitoterapia
[Mh] Termos MeSH secundário: Doenças Cardiovasculares/prevenção & controle
Transtornos Cerebrovasculares/prevenção & controle
Suplementos Nutricionais
Seres Humanos
Neoplasias/prevenção & controle
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Em] Mês de entrada:1609
[Cu] Atualização por classe:151230
[Lr] Data última revisão:
151230
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:151118
[St] Status:MEDLINE


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[PMID]:26353901
[Au] Autor:Gomes S; Torres AG
[Ad] Endereço:Laboratório de Bioquímica Nutricional e de Alimentos, Instituto de Química, Universidade Federal do Rio de Janeiro, UFRJ, Brazil.
[Ti] Título:Optimized extraction of polyphenolic antioxidant compounds from Brazil nut (Bertholletia excelsa) cake and evaluation of the polyphenol profile by HPLC.
[So] Source:J Sci Food Agric;96(8):2805-14, 2016 Jun.
[Is] ISSN:1097-0010
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: The solid residue (cake) of pressed Brazil nut oil has high energy value and contains high levels of nutrients and bioactive compounds, such as polyphenols. However, little is known about these components in this by-product. Extraction is the first step in investigating the phenolic compounds in Brazil nut cake because extraction conditions might impact the yields of phenolic compounds and antioxidant capacity. The aim of this study was to select the best phenolic compound extraction conditions for Brazil nut cake by using factorial experimental design and to characterize the phenolic compounds in the extract. RESULTS: The optimal extraction of antioxidant phenolic compounds from Brazil nut cake was achieved under the following conditions: ethanol-water (40:60; v/v); 2.5 min homogenization; and 1 h extraction at 60 °C. The phenolic compound profile of the Brazil nut cake extract using the optimized extraction was determined by high-performance liquid chromatography with photodiode array detection. Six phenolic acids (gallic acid, protocatechuic acid, 2,4-dihydroxybenzoic acid, p-hydroxybenzoic acid, p-coumaric acid and sinapic acid) and one flavonoid ((+)-catechin) were identified, and the contents of the phenolic compounds varied from 70.0 to 421 mg kg(-1) . CONCLUSION: Knowledge of the potential bioactivity of Brazil nut cake identified in the present study might promote its use in the food industry. © 2015 Society of Chemical Industry.
[Mh] Termos MeSH primário: Antioxidantes/química
Bertholletia/química
Cromatografia Líquida de Alta Pressão/métodos
Polifenóis/química
[Mh] Termos MeSH secundário: Análise de Alimentos
Estrutura Molecular
Extratos Vegetais/química
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Antioxidants); 0 (Plant Extracts); 0 (Polyphenols)
[Em] Mês de entrada:1705
[Cu] Atualização por classe:170526
[Lr] Data última revisão:
170526
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:150911
[St] Status:MEDLINE
[do] DOI:10.1002/jsfa.7448



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