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  1 / 9 MEDLINE  
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[PMID]:24261568
[Au] Autor:Kohyama TI; Matsumoto K; Katakura H
[Ad] Endereço:Department of Natural History Science, Faculty of Science, Hokkaido University, Sapporo, Hokkaido, 060-0810, Japan.
[Ti] Título:Deep phylogeographical structure and parallel host range evolution in the leaf beetle Agelasa nigriceps.
[So] Source:Mol Ecol;23(2):421-34, 2014 Feb.
[Is] ISSN:1365-294X
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:To understand the mechanisms behind the diversification of herbivorous insects through insect-plant interactions, it is important to know how the insects change their diet breadth in response to environmental changes. In this study, we investigated the phylogeographical pattern of the leaf beetle Agelasa nigriceps to infer the evolutionary history of its host range. While this beetle commonly uses Actinidia arguta (Actinidiaceae) as a host plant, it has been recorded recently on Pterostyrax hispidus (Styracaceae), which is now increasing in abundance at some localities in Japan due to the indirect effects of high population size of a mammalian herbivore. Considerable variation among populations in the ability of Ag. nigriceps to use P. hispidus suggests that P. hispidus is a newly acquired host plant for this beetle. Phylogenetic analyses using mitochondrial DNA sequences and amplified fragment length polymorphism (AFLP) revealed a high degree of phylogeographical structure in Ag. nigriceps throughout Japan, which is consistent with the hypothesis that several glacial refugia existed in the Japanese archipelago. In contrast, no genetic structure associated with the host plants was detected. Both the mitochondrial DNA and AFLP analyses showed that populations that can use P. hispidus are polyphyletic. These results and geographical variation in host use suggest that the host range expansion to a novel host, P. hispidus, is a very recent and possibly ongoing phenomenon and has occurred independently in several regions. Our study illustrates that the host range of herbivorous insects can evolve repeatedly in response to similar environmental changes.
[Mh] Termos MeSH primário: Evolução Biológica
Coleópteros/genética
Herbivoria
Filogenia
[Mh] Termos MeSH secundário: Actinidia
Análise do Polimorfismo de Comprimento de Fragmentos Amplificados
Animais
Teorema de Bayes
DNA Mitocondrial/genética
Genética Populacional
Japão
Dados de Sequência Molecular
Filogeografia
Análise de Sequência de DNA
Styracaceae
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (DNA, Mitochondrial)
[Em] Mês de entrada:1508
[Cu] Atualização por classe:171116
[Lr] Data última revisão:
171116
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:131123
[St] Status:MEDLINE
[do] DOI:10.1111/mec.12597


  2 / 9 MEDLINE  
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[PMID]:21695686
[Au] Autor:Ji HY; Oh SR; Lee HK; Na DH; Lee HS
[Ad] Endereço:Drug Metabolism and Bioanalysis Laboratory, College of Pharmacy, The Catholic University of Korea, Bucheon, Korea.
[Ti] Título:Liquid chromatography-electrospray ionization tandem mass spectrometry for the quantification of styraxlignolide A in rat plasma.
[So] Source:J Sep Sci;34(15):1828-33, 2011 Aug.
[Is] ISSN:1615-9314
[Cp] País de publicação:Germany
[La] Idioma:eng
[Ab] Resumo:Styraxlignolide A is a pharmacologically active ingredient isolated from Styrax japonica Sieb. et Zucc. A rapid, selective, and sensitive liquid chromatographic method with electrospray ionization tandem mass spectrometry was developed for use in the quantification of styraxlignolide A in rat plasma. Styraxlignolide A was extracted from rat plasma using ethyl acetate at neutral pH. The analytes were separated on an Atlantis dC18 column using a mixture of methanol and ammonium formate (10 mM, pH 3.0) (70:30, v/v) and detected by tandem mass spectrometry in multiple reaction monitoring mode. The standard curve was linear (r(2) =0.9978) over the concentration range of 100-10000 ng/mL. The lower limit of quantification was 100 ng/mL using 50 µL of plasma sample. The coefficient of variation and relative error for intra- and inter-assays at four QC levels were 1.6-8.3% and from -12.0 to -1.7%, respectively. The present method was applied successfully to the pharmacokinetic study of styraxlignolide A after intravenous administration of styraxlignolide A at a dose of 10 mg/kg in male Sprague-Dawley rats.
[Mh] Termos MeSH primário: Dissacarídeos/sangue
Lignanas/sangue
Styracaceae/química
[Mh] Termos MeSH secundário: Animais
Cromatografia Líquida
Dissacarídeos/administração & dosagem
Dissacarídeos/química
Lignanas/administração & dosagem
Lignanas/química
Masculino
Estrutura Molecular
Ratos
Ratos Sprague-Dawley
Espectrometria de Massas por Ionização por Electrospray
Espectrometria de Massas em Tandem
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Disaccharides); 0 (Lignans); 0 (styraxlignolide A)
[Em] Mês de entrada:1507
[Cu] Atualização por classe:141103
[Lr] Data última revisão:
141103
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:110623
[St] Status:MEDLINE
[do] DOI:10.1002/jssc.201100272


  3 / 9 MEDLINE  
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[PMID]:21695177
[Au] Autor:Wang O; Liu S; Zou J; Lu L; Chen L; Qiu S; Li H; Lu X
[Ad] Endereço:Institute of Genomic Medicine, Wenzhou Medical College, Wenzhou, China.
[Ti] Título:Anticancer activity of 2α, 3α, 19ß, 23ß-Tetrahydroxyurs-12-en-28-oic acid (THA), a novel triterpenoid isolated from Sinojackia sarcocarpa.
[So] Source:PLoS One;6(6):e21130, 2011.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Natural products represent an important source for agents of cancer prevention and cancer treatment. More than 60% of conventional anticancer drugs are derived from natural sources, particularly from plant-derived materials. In this study, 2α, 3α, 19ß, 23ß-tetrahydroxyurs-12-en-28-oic acid (THA), a novel triterpenoid from the leaves of Sinojackia sarcocarpa, was isolated, and its anticancer activity was investigated both in vitro and in vivo. PRINCIPAL FINDINGS: THA possessed potent tumor selected toxicity in vitro. It exhibited significantly higher cytotoxicity to the cancer cell lines A2780 and HepG2 than to IOSE144 and QSG7701, two noncancerous cell lines derived from ovary epithelium and liver, respectively. Moreover, THA showed a dose-dependent inhibitory effect on A2780 ovary tumor growth in vivo in nude mice. THA induced a dose-dependent apoptosis and G2/M cell cycle arrest in A2780 and HepG2 cells. The THA-induced cell cycle arrest was accompanied by a downregulation of Cdc2. The apoptosis induced by THA was evident by induction of DNA fragmentation, release of cytoplasmic Cytochrome c from mitochondria, activation of caspases, downregulation of Bcl-2 and upregulation of Bax. CONCLUSION: The primary data indicated that THA exhibit a high toxicity toward two cancer cells than their respective non-cancerous counterparts and has a significant anticancer activity both in vitro and in vivo. Thus, THA and/or its derivatives may have great potential in the prevention and treatment of human ovary tumors and other malignancies.
[Mh] Termos MeSH primário: Antineoplásicos/isolamento & purificação
Antineoplásicos/farmacologia
Ácido Oleanólico/análogos & derivados
Styracaceae/química
[Mh] Termos MeSH secundário: Animais
Apoptose/efeitos dos fármacos
Divisão Celular/efeitos dos fármacos
Linhagem Celular Tumoral
Feminino
Fase G2/efeitos dos fármacos
Regulação Neoplásica da Expressão Gênica/efeitos dos fármacos
Seres Humanos
Camundongos
Ácido Oleanólico/isolamento & purificação
Ácido Oleanólico/farmacologia
Ensaios Antitumorais Modelo de Xenoenxerto
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Antineoplastic Agents); 55306-03-1 (sericic acid); 6SMK8R7TGJ (Oleanolic Acid)
[Em] Mês de entrada:1110
[Cu] Atualização por classe:170220
[Lr] Data última revisão:
170220
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:110623
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0021130


  4 / 9 MEDLINE  
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[PMID]:21671207
[Au] Autor:Liu S; Cao M; Li D; Zhang J; Feng S; Nie Y; Yan L; Zhang D; Zhang Y; Yang Z; Zhao J
[Ad] Endereço:Department of Chemistry and Life Sciences, Leshan Teacher's College, Leshan 614004, PR China.
[Ti] Título:Purification and anticancer activity investigation of pentacyclic triterpenoids from the leaves of Sinojackia sarcocarpa L.Q. Luo by high-speed counter-current chromatography.
[So] Source:Nat Prod Res;25(17):1600-6, 2011 Oct.
[Is] ISSN:1478-6427
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Sinojackia sarcocarpa L.Q. Luo has high aesthetic value, which is clinically used to treat diseases such as the variations of arthritis, thromboangiitis obliterans, angina pectoris as well as many other diseases. Pentacyclic triterpenoids are the main pharmacological effective compounds. High-speed counter-current chromatography method was performed on a Midi-DE centrifuge at 25°C. The solvent system was n-hexane-ethylacetate-methanol-water (10:5:3:1, v/v). Peak fractions were collected according to the elution profile for subsequent high-performance liquid chromatography analysis. The structure identification was performed by ultraviolet, infrared, mass spectrometry, (1)H-NMR and (13)C-NMR. Compound 2α,3α,19ß,23ß-tetrahydroxyurs-12-en-28-oic acid and 2α,3α,23ß-trihydroxyurs-12-en-28-oic acid were purified from the plant of Styracaceaen genius for the first time, whose purities were 96.57% and 97.33%, respectively. Compared with the same dose of oral 5-fluorouracil with 57.6% inhibition rate, the S(180) tumour inhibition rates of 20 mg kg(-1)d(-1) two compounds were 59.5% and 48.9%, respectively.
[Mh] Termos MeSH primário: Anticarcinógenos/farmacologia
Triterpenos Pentacíclicos/isolamento & purificação
Triterpenos Pentacíclicos/farmacologia
Folhas de Planta/química
Styracaceae/química
[Mh] Termos MeSH secundário: Animais
Anticarcinógenos/isolamento & purificação
Divisão Celular/efeitos dos fármacos
Cromatografia Líquida de Alta Pressão
Distribuição Contracorrente
Espectroscopia de Ressonância Magnética
Espectrometria de Massas
Camundongos
Estrutura Molecular
Ensaios Antitumorais Modelo de Xenoenxerto
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Anticarcinogenic Agents); 0 (Pentacyclic Triterpenes)
[Em] Mês de entrada:1202
[Cu] Atualização por classe:111020
[Lr] Data última revisão:
111020
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:110615
[St] Status:MEDLINE
[do] DOI:10.1080/14786419.2010.496115


  5 / 9 MEDLINE  
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[PMID]:21309987
[Au] Autor:Yao X; Zhang J; Ye Q; Huang H
[Ad] Endereço:Key Laboratory of Plant Germplasm Enhancement and Speciality Agriculture, Wuhan Botanical Garden, Chinese Academy of Sciences, Wuhan, Hubei, China.
[Ti] Título:Fine-scale spatial genetic structure and gene flow in a small, fragmented population of Sinojackia rehderiana (Styracaceae), an endangered tree species endemic to China.
[So] Source:Plant Biol (Stuttg);13(2):401-10, 2011 Mar.
[Is] ISSN:1438-8677
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Populations of Sinojackia rehderiana are highly threatened and have small and scattered distribution due to habitat fragmentation and human activities. Understanding changes in genetic diversity, the fine-scale spatial genetic structure (SGS) at different life stages and gene flow of S. rehderiana is critical for developing successful conservation strategies for fragmented populations of this endangered species. In this study, 208 adults, 114 juveniles and 136 seedlings in a 50 × 100-m transect within an old-growth forest were mapped and genotyped using eight microsatellite makers to investigate the genetic diversity and SGS of this species. No significant differences in genetic diversity among different life-history stages were found. However, a significant heterozygote deficiency in adults and seedlings may result from substantial biparental inbreeding. Significant fine-scale spatial structure was found in different life-history stages within 19 m, suggesting that seed dispersal mainly occurred near a mother tree. Both historical and contemporary estimates of gene flow (13.06 and 16.77 m) indicated short-distance gene dispersal in isolated populations of S. rehderiana. The consistent spatial structure revealed in different life stages is most likely the result of limited gene flow. Our results have important implications for conservation of extant populations of S. rehderiana. Measures for promoting pollen flow should be taken for in situ conservation. The presence of a SGS in fragmented populations implies that seeds for ex situ conservation should be collected from trees at least 19-m apart to reduce genetic similarity between neighbouring individuals.
[Mh] Termos MeSH primário: Espécies em Perigo de Extinção
Fluxo Gênico
Variação Genética
Genética Populacional
Styracaceae/genética
[Mh] Termos MeSH secundário: China
DNA de Plantas/genética
Ecossistema
Genótipo
Repetições de Microssatélites
Dispersão de Sementes
Plântulas/genética
Análise de Sequência de DNA
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (DNA, Plant)
[Em] Mês de entrada:1105
[Cu] Atualização por classe:151119
[Lr] Data última revisão:
151119
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:110212
[St] Status:MEDLINE
[do] DOI:10.1111/j.1438-8677.2010.00361.x


  6 / 9 MEDLINE  
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[PMID]:18245106
[Au] Autor:Yao X; Ye Q; Fritsch PW; Cruz BC; Huang H
[Ad] Endereço:Wuhan Botanical Garden, The Chinese Academy of Sciences, Moshan, Wuhan 430074, China.
[Ti] Título:Phylogeny of Sinojackia (Styracaceae) based on DNA sequence and microsatellite data: implications for taxonomy and conservation.
[So] Source:Ann Bot;101(5):651-9, 2008 Apr.
[Is] ISSN:1095-8290
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:BACKGROUND AND AIMS: The genus Sinojackia consists of eight species, all endemic to China. All species of Sinojackia are endangered or threatened owing to poor recruitment within populations. Information on molecular phylogenetics is critical for developing successful conservation strategies for this genus. METHODS: Combined DNA sequence data from the nuclear ribosomal internal transcribed spacer regions and plastid psbA-trnH intergenic spacer and microsatellite data were used to infer a phylogeny of the genus. KEY RESULTS: Parsimony analysis of the combined sequence data and multivariate analysis based on fruit characters indicated that Sinojackia dolichocarpa is monophyletic and genetically well separated from the other Sinojackia species, thus supporting its rank at the generic level as Changiostyrax. Phylogenetic relationships within Sinojackia sensu stricto are unresolved from the combined sequence data. A UPGMA dendrogram based on seven microsatellite loci of 96 individual plants yielded a first-diverging cluster of all individuals of S. microcarpa. The remaining species form another cluster without any definitive patterns corresponding to current species circumscriptions, suggesting either extensive hybridization or incipient speciation. CONCLUSIONS: The results suggest that there are too many species recognized within Sinojackia sensu stricto, but this must be further assessed with comprehensive morphological and taxonomic revisionary work. The implications of the phylogenetic data for conservation are discussed.
[Mh] Termos MeSH primário: Conservação dos Recursos Naturais
DNA de Plantas/genética
Repetições de Microssatélites/genética
Filogenia
Styracaceae/classificação
Styracaceae/genética
[Mh] Termos MeSH secundário: Sequência de Bases
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (DNA, Plant)
[Em] Mês de entrada:0804
[Cu] Atualização por classe:170220
[Lr] Data última revisão:
170220
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:080205
[St] Status:MEDLINE
[do] DOI:10.1093/aob/mcm332


  7 / 9 MEDLINE  
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[PMID]:17888124
[Au] Autor:Yao X; Ye Q; Kang M; Huang H
[Ad] Endereço:Wuhan Botanical Garden/Wuhan Institute of Botany, Chinese Academy of Sciences, Wuhan 430074, Hubei, China.
[Ti] Título:Microsatellite analysis reveals interpopulation differentiation and gene flow in the endangered tree Changiostyrax dolichocarpa (Styracaceae) with fragmented distribution in central China.
[So] Source:New Phytol;176(2):472-80, 2007.
[Is] ISSN:0028-646X
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Polymorphic simple sequence repeat (SSR) markers were used to investigate the impact of habitat fragmentation on the population structure and gene flow of Changiostyrax dolichocarpa, a critically endangered tree in central China. Intrapopulation genetic diversity, population structure and gene flow in the five extant populations of this species were analysed by eight SSR markers. Intrapopulation genetic diversity results suggest that C. dolichocarpa remnants maintained a relatively high degree of genetic diversity despite severe fragmentation. Low genetic differentiation among populations was found based on Wright's F(ST) and amova analysis. Both the F(ST)-based estimate and private allele method revealed high historical gene flow among the remnant populations. Recent immigrants, detected by assignment tests, tend to decrease from the grandparent generation to the current generation. The potentially highly restricted current gene flow among fragments may render the fragmented populations of C. dolichocarpa at a higher risk of local extinction several generations after fragmentation. Both in situ and ex situ conservation management for the remnant populations of C. dolichocarpa are therefore urgently needed to rescue remaining genetic diversity.
[Mh] Termos MeSH primário: Fluxo Gênico
Repetições de Microssatélites
Styracaceae/genética
[Mh] Termos MeSH secundário: Alelos
Teorema de Bayes
China
Conservação dos Recursos Naturais
Extinção Biológica
Repetições Minissatélites
Polimorfismo Genético
Densidade Demográfica
Dinâmica Populacional
Styracaceae/crescimento & desenvolvimento
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Em] Mês de entrada:0712
[Cu] Atualização por classe:070924
[Lr] Data última revisão:
070924
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:070925
[St] Status:MEDLINE


  8 / 9 MEDLINE  
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[PMID]:12234576
[Au] Autor:Yayla Y; Alankus-Caliskan O; Anil H; Bates RB; Stessman CC; Kane VV
[Ad] Endereço:Ege University, Faculty of Science, Department of Chemistry, 35100 Bornova, Izmir, Turkey. y_yayla@yahoo.com
[Ti] Título:Saponins from Styrax officinalis.
[So] Source:Fitoterapia;73(4):320-6, 2002 Jul.
[Is] ISSN:0367-326X
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:Three triterpene saponins named Styrax-saponin A-C (1-3) were found in pericarps of Styrax officinalis together with the deacylsaponin (4). Structural determinations were achieved using 1D-, 2D-NMR and mass spectrometry.
[Mh] Termos MeSH primário: Fitoterapia
Extratos Vegetais/química
Saponinas/química
Styracaceae
[Mh] Termos MeSH secundário: Seres Humanos
Espectroscopia de Ressonância Magnética
Espectrometria de Massas
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Plant Extracts); 0 (Saponins)
[Em] Mês de entrada:0212
[Cu] Atualização por classe:061115
[Lr] Data última revisão:
061115
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:020918
[St] Status:MEDLINE


  9 / 9 MEDLINE  
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[PMID]:12102532
[Au] Autor:Miyazaki Y; Hiura T; Kato E; Funada R
[Ad] Endereço:Laboratory of Wood Biology, Graduate School of Agriculture, Hokkaido University, Sapporo, Japan.
[Ti] Título:Allocation of resources to reproduction in Styrax obassia in a masting year.
[So] Source:Ann Bot;89(6):767-72, 2002 Jun.
[Is] ISSN:0305-7364
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:An analysis is presented of three possible pathways of reproductive allocation, namely, allocation of resources to reproductive organs from reproductive shoots, from non-reproductive shoots and from the main trunk. These pathways were examined by comparing the amount of storage starch in reproductive shoots, non-reproductive shoots and the main trunk in Styrax obassia, a typical masting tree species, during a year of little flowering (1999) and in a mass-flowering year (2000). In addition, we measured rates of light-saturated photosynthesis in leaves of reproductive and non-reproductive shoots to examine the contribution of photosynthetic production to reproductive costs. In both the main trunk and non-reproductive shoots the pattern of seasonal variation in the amount of starch did not differ between 1999 and 2000. However, in the mass-flowering year, the amount of starch in the reproductive shoots was less than that in non-reproductive shoots during the growing season. Thus, reproductive shoots bore most of the cost of reproduction, although non-reproductive shoots and the main trunk also bore some of the cost. Mass-based rates of light-saturated photosynthesis of the leaves of reproductive shoots were significantly higher than those of non-reproductive shoots during both the flowering and the fruiting period. However, leaves of reproductive shoots had a significantly smaller area, a lower mass per area, and lower concentrations of nitrogen than leaves of non-reproductive shoots, although the number of leaves did not differ between the two types of shoots. Therefore, the amount of photosynthate per shoot was significantly lower in reproductive shoots than in non-reproductive shoots. These results suggest that the cost of reproduction depends predominantly on storage starch in reproductive shoots, although it is still unclear how much photosynthate is allocated to reproductive organs from non-reproductive shoots.
[Mh] Termos MeSH primário: Reprodução/fisiologia
Styracaceae/fisiologia
[Mh] Termos MeSH secundário: Fertilidade/fisiologia
Fotossíntese
Folhas de Planta/fisiologia
Brotos de Planta/fisiologia
Estações do Ano
Especificidade da Espécie
Amido/metabolismo
Fatores de Tempo
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
9005-25-8 (Starch)
[Em] Mês de entrada:0208
[Cu] Atualização por classe:170219
[Lr] Data última revisão:
170219
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:020710
[St] Status:MEDLINE



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