Base de dados : MEDLINE Pesquisa : B01.650.940.800.575.912.250.401.194 [Categoria DeCS] Referências encontradas : 31 [refinar] Mostrando: 1 .. 10   no formato [Detalhado]

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[PMID]: 26125883 [Au] Autor: Schlottfeldt S; Walter ME; Carvalho AC; Soares TN; Telles MP; Loyola RD; Diniz-Filho JA [Ad] Endereço: Departamento de Ciência da Computação, Instituto de Ciências Exatas, Universidade de Brasília, Brasília, DF, Brasil shanass@unb.br. [Ti] Título: Multi-objective optimization in systematic conservation planning and the representation of genetic variability among populations. [So] Source: Genet Mol Res;14(2):6744-61, 2015 Jun 18. [Is] ISSN: 1676-5680 [Cp] País de publicação: Brazil [La] Idioma: eng [Ab] Resumo: Biodiversity crises have led scientists to develop strategies for achieving conservation goals. The underlying principle of these strategies lies in systematic conservation planning (SCP), in which there are at least 2 conflicting objectives, making it a good candidate for multi-objective optimization. Although SCP is typically applied at the species level (or hierarchically higher), it can be used at lower hierarchical levels, such as using alleles as basic units for analysis, for conservation genetics. Here, we propose a method of SCP using a multi-objective approach. We used non-dominated sorting genetic algorithm II in order to identify the smallest set of local populations of Dipteryx alata (baru) (a Brazilian Cerrado species) for conservation, representing the known genetic diversity and using allele frequency information associated with heterozygosity and Hardy-Weinberg equilibrium. We worked in 3 variations for the problem. First, we reproduced a previous experiment, but using a multi-objective approach. We found that the smallest set of populations needed to represent all alleles under study was 7, corroborating the results of the previous study, but with more distinct solutions. In the 2nd and 3rd variations, we performed simultaneous optimization of 4 and 5 objectives, respectively. We found similar but refined results for 7 populations, and a larger portfolio considering intra-specific diversity and persistence with populations ranging from 8-22. This is the first study to apply multi-objective algorithms to an SCP problem using alleles at the population level as basic units for analysis. [Mh] Termos MeSH primário: Algoritmos Alelos Conservação dos Recursos Naturais/estatística & dados numéricos Dipteryx/genética Variação Genética [Mh] Termos MeSH secundário: Brasil Conservação dos Recursos Naturais/métodos Frequência do Gene Heterozigoto Seres Humanos Repetições de Microssatélites [Pt] Tipo de publicação: JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T [Em] Mês de entrada: 1603 [Cu] Atualização por classe: 150701 [Lr] Data última revisão: 150701 [Sb] Subgrupo de revista: IM [Da] Data de entrada para processamento: 150701 [St] Status: MEDLINE [do] DOI: 10.4238/2015.June.18.18

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[PMID]: 25603895 [Au] Autor: Diniz-Filho JA; Rodrigues H; Telles MP; Oliveira GD; Terribile LC; Soares TN; Nabout JC [Ad] Endereço: Departamento de Ecologia, Universidade Federal de Goiás (UFG), Goiânia, GO, Brazil. [Ti] Título: Correlation between genetic diversity and environmental suitability: taking uncertainty from ecological niche models into account. [So] Source: Mol Ecol Resour;15(5):1059-66, 2015 Sep. [Is] ISSN: 1755-0998 [Cp] País de publicação: England [La] Idioma: eng [Ab] Resumo: The hindcast of shifts in the geographical ranges of species as estimated by ecological niche modelling (ENM) has been coupled with phylogeographical patterns, allowing the inference of past processes that drove population differentiation and genetic variability. However, more recently, some studies have suggested that maps of environmental suitability estimated by ENM may be correlated to species' abundance, raising the possibility of using environmental suitability to infer processes related to population demographic dynamics and genetic variability. In both cases, one of the main problems is that there is a wide variation in ENM development methods and climatic models. In this study, we analyse the relationship between heterozygosity (He) and environmental suitability from multiple ENMs for 25 population estimates for Dipteryx alata, a widely distributed, endemic tree species of the Cerrado region of central Brazil. We propose a new approach for generating a statistical distribution of correlations under randomly generated ENM. The confidence intervals from these distributions indicate how model selection with different properties affects the ability to detect a correlation of interest (e.g. the correlation between He and suitability). Additionally, our approach allows us to explore which particular ensemble of ENMs produces the better result for finding an association between environmental suitability and He. Caution is necessary when choosing a method or a climatic data set for modelling geographical distributions, but the new approach proposed here provides a conservative way to evaluate the ability of ensembles to detect patterns of interest. [Mh] Termos MeSH primário: Dipteryx/classificação Dipteryx/genética Variação Genética Filogeografia [Mh] Termos MeSH secundário: Bioestatística Brasil Clima Ecossistema Modelos Teóricos Dinâmica Populacional [Pt] Tipo de publicação: JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T [Em] Mês de entrada: 1605 [Cu] Atualização por classe: 150811 [Lr] Data última revisão: 150811 [Sb] Subgrupo de revista: IM [Da] Data de entrada para processamento: 150122 [St] Status: MEDLINE [do] DOI: 10.1111/1755-0998.12374

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[PMID]: 25581442 [Au] Autor: Spielmann A; Harris SA; Boshier DH; Vinson CC [Ad] Endereço: St Edmund Hall, Oxford, OX1 4AR, UK. [Ti] Título: orchard: Paternity program for autotetraploid species. [So] Source: Mol Ecol Resour;15(4):915-20, 2015 Jul. [Is] ISSN: 1755-0998 [Cp] País de publicação: England [La] Idioma: eng [Ab] Resumo: Advances in molecular marker technology have provided new opportunities to study the population genetics of polyploid taxa. Paternity analysis using microsatellite markers can be used in detection of gene flow between individuals and populations, in mating system analysis, to identify factors that influence fecundity and fertility, to identify behaviour of parent-offspring relationships and in the analysis of the reproductive success of different ecological groups. As there is no specific program for carrying out paternity analysis in tetraploid species, specialized software was designed for the assignment of paternity for autotetraploid species. orchard is a novel implementation of exclusion and likelihood statistics for carrying out paternity analysis of autotetraploids. First, the program performs an exclusion method, and then, a likelihood statistic is used with nonexcluded candidate fathers. Optional features include estimation of allele dosage of known mother trees and the estimation of pollen flow distances. orchard was tested using a data set of microsatellite data of Dipteryx odorata, a tetraploid Amazonian tree species. [Mh] Termos MeSH primário: Biologia Computacional/métodos Impressões Digitais de DNA Dipteryx/genética Dipteryx/fisiologia Fluxo Gênico Reprodução [Mh] Termos MeSH secundário: Repetições de Microssatélites Software [Pt] Tipo de publicação: JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T [Em] Mês de entrada: 1603 [Cu] Atualização por classe: 150623 [Lr] Data última revisão: 150623 [Sb] Subgrupo de revista: IM [Da] Data de entrada para processamento: 150113 [St] Status: MEDLINE [do] DOI: 10.1111/1755-0998.12370

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[PMID]: 25402015 [Au] Autor: Vinson CC; Kanashiro M; Harris SA; Boshier DH [Ad] Endereço: Department of Plant Sciences, University of Oxford, South Parks Road, Oxford, OX1 3RB, UK. [Ti] Título: Impacts of selective logging on inbreeding and gene flow in two Amazonian timber species with contrasting ecological and reproductive characteristics. [So] Source: Mol Ecol;24(1):38-53, 2015 Jan. [Is] ISSN: 1365-294X [Cp] País de publicação: England [La] Idioma: eng [Ab] Resumo: Selective logging in Brazil allows for the removal of up to 90% of trees above 50 cm diameter of a given timber species, independent of a species' life history characteristics or how quickly it will recover. The genetic and demographic effects of selective logging on two Amazonian timber species (Dipteryx odorata Leguminosae, Jacaranda copaia Bignoniaceae) with contrasting ecological and reproductive characteristics were assessed in the same forest. Genetic diversity and gene flow were characterized by genotyping adults and seed sampled before and after logging, using hypervariable microsatellite markers. Overall, there were no short-term genetic impacts on the J. copaia population, with commercial application of current Brazilian forest management regulations. In contrast, for D. Odorata, selective logging showed a range of genetic impacts, with a 10% loss of alleles, and reductions in siring by pollen from trees within the 546-ha study area (23-11%) and in the number of pollen donors per progeny array (2.8-1.6), illustrating the importance of the surrounding landscape. Asynchrony in flowering between D. odorata trees led to trees with no breeding partners, which could limit the species reproduction and regeneration under current regulations. The results are summarized with other published studies from the same site and the implications for forest management discussed. The different types and levels of impacts associated with each species support the idea that ecological and genetic information by species, ecological guild or reproductive group is essential in helping to derive sustainable logging guidelines for tropical forests. [Mh] Termos MeSH primário: Bignoniaceae/genética Dipteryx/genética Agricultura Florestal/métodos Fluxo Gênico Endogamia Árvores/genética [Mh] Termos MeSH secundário: Brasil Conservação dos Recursos Naturais Variação Genética Genótipo Repetições de Microssatélites Pólen/genética Dinâmica Populacional [Pt] Tipo de publicação: JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T [Em] Mês de entrada: 1503 [Cu] Atualização por classe: 150108 [Lr] Data última revisão: 150108 [Sb] Subgrupo de revista: IM [Da] Data de entrada para processamento: 141118 [St] Status: MEDLINE [do] DOI: 10.1111/mec.13002

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MEDLINE

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[PMID]: 24424164 [Au] Autor: Vinson CC; Kanashiro M; Sebbenn AM; Williams TC; Harris SA; Boshier DH [Ad] Endereço: Department of Plant Sciences, University of Oxford, South Parks Road, Oxford, UK. [Ti] Título: Long-term impacts of selective logging on two Amazonian tree species with contrasting ecological and reproductive characteristics: inferences from Eco-gene model simulations. [So] Source: Heredity (Edinb);115(2):130-9, 2015 Aug. [Is] ISSN: 1365-2540 [Cp] País de publicação: England [La] Idioma: eng [Ab] Resumo: The impact of logging and subsequent recovery after logging is predicted to vary depending on specific life history traits of the logged species. The Eco-gene simulation model was used to evaluate the long-term impacts of selective logging over 300 years on two contrasting Brazilian Amazon tree species, Dipteryx odorata and Jacaranda copaia. D. odorata (Leguminosae), a slow growing climax tree, occurs at very low densities, whereas J. copaia (Bignoniaceae) is a fast growing pioneer tree that occurs at high densities. Microsatellite multilocus genotypes of the pre-logging populations were used as data inputs for the Eco-gene model and post-logging genetic data was used to verify the output from the simulations. Overall, under current Brazilian forest management regulations, there were neither short nor long-term impacts on J. copaia. By contrast, D. odorata cannot be sustainably logged under current regulations, a sustainable scenario was achieved by increasing the minimum cutting diameter at breast height from 50 to 100 cm over 30-year logging cycles. Genetic parameters were only slightly affected by selective logging, with reductions in the numbers of alleles and single genotypes. In the short term, the loss of alleles seen in J. copaia simulations was the same as in real data, whereas fewer alleles were lost in D. odorata simulations than in the field. The different impacts and periods of recovery for each species support the idea that ecological and genetic information are essential at species, ecological guild or reproductive group levels to help derive sustainable management scenarios for tropical forests. [Mh] Termos MeSH primário: Bignoniaceae/genética Conservação dos Recursos Naturais Dipteryx/genética Agricultura Florestal Modelos Genéticos [Mh] Termos MeSH secundário: Alelos Brasil Genética Populacional Genótipo Repetições de Microssatélites Árvores/genética [Pt] Tipo de publicação: JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T [Em] Mês de entrada: 1511 [Cu] Atualização por classe: 170220 [Lr] Data última revisão: 170220 [Sb] Subgrupo de revista: IM [Da] Data de entrada para processamento: 140116 [St] Status: MEDLINE [do] DOI: 10.1038/hdy.2013.146

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[PMID]: 24806579 [Au] Autor: Ferraz MC; Yoshida EH; Tavares RV; Cogo JC; Cintra AC; Dal Belo CA; Franco LM; dos Santos MG; Resende FA; Varanda EA; Hyslop S; Puebla P; San Feliciano A; Oshima-Franco Y [Ad] Endereço: Post-Graduate Program in Pharmaceutical Sciences, University of Sorocaba (UNISO), Rodovia Raposo Tavares, Km 92.5, 18023-000 Sorocaba, SP, Brazil. miriele.ferraz@gmail.com. [Ti] Título: An isoflavone from Dipteryx alata Vogel is active against the in vitro neuromuscular paralysis of Bothrops jararacussu snake venom and bothropstoxin I, and prevents venom-induced myonecrosis. [So] Source: Molecules;19(5):5790-805, 2014 May 06. [Is] ISSN: 1420-3049 [Cp] País de publicação: Switzerland [La] Idioma: eng [Ab] Resumo: Snakebite is a neglected disease and serious health problem in Brazil, with most bites being caused by snakes of the genus Bothrops. Although serum therapy is the primary treatment for systemic envenomation, it is generally ineffective in neutralizing the local effects of these venoms. In this work, we examined the ability of 7,8,3'-trihydroxy-4'-methoxyisoflavone (TM), an isoflavone from Dipteryx alata, to neutralize the neurotoxicity (in mouse phrenic nerve-diaphragm preparations) and myotoxicity (assessed by light microscopy) of Bothrops jararacussu snake venom in vitro. The toxicity of TM was assessed using the Salmonella microsome assay (Ames test). Incubation with TM alone (200 µg/mL) did not alter the muscle twitch tension whereas incubation with venom (40 µg/mL) caused irreversible paralysis. Preincubation of TM (200 µg/mL) with venom attenuated the venom-induced neuromuscular blockade by 84% ± 5% (mean ± SEM; n = 4). The neuromuscular blockade caused by bothropstoxin-I (BthTX-I), the major myotoxic PLA2 of this venom, was also attenuated by TM. Histological analysis of diaphragm muscle incubated with TM showed that most fibers were preserved (only 9.2% ± 1.7% were damaged; n = 4) compared to venom alone (50.3% ± 5.4% of fibers damaged; n = 3), and preincubation of TM with venom significantly attenuated the venom-induced damage (only 17% ± 3.4% of fibers damaged; n = 3; p < 0.05 compared to venom alone). TM showed no mutagenicity in the Ames test using Salmonella strains TA98 and TA97a with (+S9) and without (-S9) metabolic activation. These findings indicate that TM is a potentially useful compound for antagonizing the neuromuscular effects (neurotoxicity and myotoxicity) of B. jararacussu venom. [Mh] Termos MeSH primário: Proteínas Sanguíneas/química Isoflavonas/química Músculo Esquelético/efeitos dos fármacos Bloqueio Neuromuscular Venenos de Serpentes/toxicidade [Mh] Termos MeSH secundário: Animais Proteínas Sanguíneas/administração & dosagem Proteínas Sanguíneas/isolamento & purificação Bothrops/metabolismo Brasil Venenos de Crotalídeos/administração & dosagem Venenos de Crotalídeos/antagonistas & inibidores Dipteryx/química Seres Humanos Técnicas In Vitro Isoflavonas/administração & dosagem Isoflavonas/isolamento & purificação Camundongos Músculo Esquelético/patologia Necrose/tratamento farmacológico Extratos Vegetais/administração & dosagem Extratos Vegetais/química Venenos de Serpentes/química [Pt] Tipo de publicação: JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T [Nm] Nome de substância: 0 (Blood Proteins); 0 (Bothrops jararaca inhibitor); 0 (Crotalid Venoms); 0 (Isoflavones); 0 (Plant Extracts); 0 (Snake Venoms); 116189-59-4 (bothropstoxin) [Em] Mês de entrada: 1412 [Cu] Atualização por classe: 140508 [Lr] Data última revisão: 140508 [Sb] Subgrupo de revista: IM [Da] Data de entrada para processamento: 140509 [St] Status: MEDLINE [do] DOI: 10.3390/molecules19055790

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[PMID]: 24162589 [Au] Autor: Diniz-Filho JA; Diniz JV; Rangel TF; Soares TN; Telles MP; Collevatti RG; Bini LM [Ad] Endereço: Laboratório de Ecologia Teórica e Síntese, Departamento de Ecologia, Instituto de Ciências Biológica (ICB), Universidade Federal de Goiás (UFG), C.P. 131, Goiânia, GO, 74001-970, Brazil, diniz@ufg.br. [Ti] Título: A new eigenfunction spatial analysis describing population genetic structure. [So] Source: Genetica;141(10-12):479-89, 2013 Dec. [Is] ISSN: 1573-6857 [Cp] País de publicação: Netherlands [La] Idioma: eng [Ab] Resumo: Several methods of spatial analyses have been proposed to infer the relative importance of evolutionary processes on genetic population structure. Here we show how a new eigenfunction spatial analysis can be used to model spatial patterns in genetic data. Considering a sample of n local populations, the method starts by modeling the response variable (allele frequencies or phenotypic variation) against the eigenvectors sequentially extracted from a geographic distance matrix (n × n). The relationship between the coefficient of determination (R(2)) of the models and the cumulative eigenvalues, which we named the spatial signal-representation (SSR) curve, can be more efficient than Moran's I correlograms in describing different patterns. The SSR curve was also applied to simulated data (under distinct scenarios of population differentiation) and to analyze spatial patterns in alleles from microsatellite data for 25 local populations of Dipteryx alata, a tree species endemic to the Brazilian Cerrado. The SSR curves are consistent with previous phylogeographical patterns of the species, revealing combined effects of isolation-by-distance and range expansion. Our analyses demonstrate that the SSR curve is a useful exploratory tool for describing spatial patterns of genetic variability and for selecting spatial eigenvectors for models aiming to explain spatial responses to environmental variables and landscape features. [Mh] Termos MeSH primário: Dipteryx/genética Frequência do Gene Genoma de Planta Repetições de Microssatélites Modelos Genéticos Análise Espacial [Mh] Termos MeSH secundário: Algoritmos Simulação por Computador Epigênese Genética Variação Genética Genética Populacional Filogeografia Seleção Genética [Pt] Tipo de publicação: JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T [Em] Mês de entrada: 1407 [Cu] Atualização por classe: 171020 [Lr] Data última revisão: 171020 [Sb] Subgrupo de revista: IM [Da] Data de entrada para processamento: 131029 [St] Status: MEDLINE [do] DOI: 10.1007/s10709-013-9747-0

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[PMID]: 23591520 [Au] Autor: Collevatti RG; Telles MP; Nabout JC; Chaves LJ; Soares TN [Ad] Endereço: Departamento de Biologia Geral, Laboratório de Genética & Biodiversidade, Instituto de Ciências Biológicas, Universidade Federal de Goiás, Goiânia, Brazil. rosanegc68@hotmail.com [Ti] Título: Demographic history and the low genetic diversity in Dipteryx alata (Fabaceae) from Brazilian Neotropical savannas. [So] Source: Heredity (Edinb);111(2):97-105, 2013 Aug. [Is] ISSN: 1365-2540 [Cp] País de publicação: England [La] Idioma: eng [Ab] Resumo: Genetic effects of habitat fragmentation may be undetectable because they are generally a recent event in evolutionary time or because of confounding effects such as historical bottlenecks and historical changes in species' distribution. To assess the effects of demographic history on the genetic diversity and population structure in the Neotropical tree Dipteryx alata (Fabaceae), we used coalescence analyses coupled with ecological niche modeling to hindcast its distribution over the last 21 000 years. Twenty-five populations (644 individuals) were sampled and all individuals were genotyped using eight microsatellite loci. All populations presented low allelic richness and genetic diversity. The estimated effective population size was small in all populations and gene flow was negligible among most. We also found a significant signal of demographic reduction in most cases. Genetic differentiation among populations was significantly correlated with geographical distance. Allelic richness showed a spatial cline pattern in relation to the species' paleodistribution 21 kyr BP (thousand years before present), as expected under a range expansion model. Our results show strong evidences that genetic diversity in D. alata is the outcome of the historical changes in species distribution during the late Pleistocene. Because of this historically low effective population size and the low genetic diversity, recent fragmentation of the Cerrado biome may increase population differentiation, causing population decline and compromising long-term persistence. [Mh] Termos MeSH primário: Alelos DNA de Plantas/genética Dipteryx/genética Modelos Genéticos Dispersão Vegetal/genética [Mh] Termos MeSH secundário: Evolução Biológica Brasil Ecossistema Fluxo Gênico Variação Genética Repetições de Microssatélites Filogeografia [Pt] Tipo de publicação: JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T [Nm] Nome de substância: 0 (DNA, Plant) [Em] Mês de entrada: 1401 [Cu] Atualização por classe: 170220 [Lr] Data última revisão: 170220 [Sb] Subgrupo de revista: IM [Da] Data de entrada para processamento: 130418 [St] Status: MEDLINE [do] DOI: 10.1038/hdy.2013.23

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[PMID]: 22886007 [Au] Autor: Diniz-Filho JA; Collevatti RG; Soares TN; Telles MP [Ad] Endereço: Departamento de Ecologia, Instituto de Ciências Biológicas, Universidade Federal de Goiás, Goiânia, GO, Brazil. diniz@icb.ufg.br [Ti] Título: Geographical patterns of turnover and nestedness-resultant components of allelic diversity among populations. [So] Source: Genetica;140(4-6):189-95, 2012 Jun. [Is] ISSN: 1573-6857 [Cp] País de publicação: Netherlands [La] Idioma: eng [Ab] Resumo: The analysis of geographical patterns in population divergence has always been a powerful way to infer microevolutionary processes involved in population differentiation, and several approaches have been used to investigate such patterns. Most frequently, multivariate spatial patterns of population differentiation are analyzed by computing pairwise genetic distances or F(ST) (or related statistics, such as Ï•(ST) from AMOVA), which are then correlated with geographical distances or landscape features. However, when calculating distances, especially based on presence-absence of alleles in local populations, there would be a confounding effect of allelic richness differences in the population differentiation. Moreover, the relative magnitude of these components and their spatial patterns can help identifying microevolutionary processes driving population differentiation. Here we show how recent methodological advances in ecological community analyses that allows partitioning dissimilarity into turnover (turnover) and richness differences, or nestedness-resultant dissimilarity, can be applied to allelic variation data, using an endemic Cerrado tree (Dipteryx alata) as a case study. Individuals from 15 local populations were genotyped for eight microsatellite loci, and pairwise dissimilarities were computed based on presence-absence of alleles. The turnover of alleles among populations represented 69 % of variation in dissimilarity, but only the richness difference component shows a clear spatial structure, appearing as a westward decrease of allelic richness. We show that decoupling richness difference and turnover components of allelic variation reveals more clearly how similarity among populations reflects geographical patterns in allelic diversity that can be interpreted in respect to historical range expansion in the species. [Mh] Termos MeSH primário: Alelos Dipteryx/genética Variação Genética Árvores/genética [Mh] Termos MeSH secundário: Geografia Repetições de Microssatélites/genética [Pt] Tipo de publicação: JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T [Em] Mês de entrada: 1301 [Cu] Atualização por classe: 171020 [Lr] Data última revisão: 171020 [Sb] Subgrupo de revista: IM [Da] Data de entrada para processamento: 120814 [St] Status: MEDLINE

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[PMID]: 22782581 [Au] Autor: Diniz-Filho JA; Collevatti RG; Chaves LJ; Soares TN; Nabout JC; Rangel TF; Melo DB; Lima JS; Telles MP [Ad] Endereço: Departamento de Ecologia, Instituto de Ciências Biológicas, Universidade Federal de Goiás, Goiânia, GO, Brasil. [Ti] Título: Geographic shifts in climatically suitable areas and loss of genetic variability in Dipteryx alata ("Baru" Tree; Fabaceae). [So] Source: Genet Mol Res;11(2):1618-26, 2012 Jun 15. [Is] ISSN: 1676-5680 [Cp] País de publicação: Brazil [La] Idioma: eng [Ab] Resumo: Many species are expected to suffer strong shifts in their geographic ranges due to climate changes in the next 50 years, with severe consequences for biodiversity patterns and population structure. We used here an ensemble forecast approach for obtaining species' range in which multiple species distribution models and climatic models were combined to model loss of genetic variability in Baru, Dipteryx alata (Fabaceae), an economically important Neotropical tree native to the Cerrado of Brazil. We estimated a series of genetic parameters (number of alleles per locus, expected heterozygosity under Hardy-Weinberg equilibrium and mutation-drift equilibrium) for this species based on eight microsatellite loci. We then recalculated these parameters assuming that local populations in areas of low future environmental suitability will go extinct. All genetic parameters remained approximately constant up to a 50% threshold of climatic suitability in the future; after this critical threshold there is an abrupt reduction in all parameters, although the magnitude of shift is only about 10% of current values, on average. Thus, despite the shifts in geographic range and climatically suitable areas towards southeastern Brazil, our analyses do not predict a strong loss of genetic diversity in D. alata because of the broad tolerance of this species, which ensures large future ranges, contrasting with other Cerrado species that have been analyzed in a similar manner. [Mh] Termos MeSH primário: Dipteryx/genética [Mh] Termos MeSH secundário: Dipteryx/classificação Variação Genética/genética Geografia Repetições de Microssatélites/genética [Pt] Tipo de publicação: JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T [Em] Mês de entrada: 1209 [Cu] Atualização por classe: 120711 [Lr] Data última revisão: 120711 [Sb] Subgrupo de revista: IM [Da] Data de entrada para processamento: 120712 [St] Status: MEDLINE [do] DOI: 10.4238/2012.June.15.11

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