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Pesquisa : B01.650.940.800.575.912.250.401.906 [Categoria DeCS]
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  1 / 911 MEDLINE  
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[PMID]:29301047
[Au] Autor:Stasek DJ; Radl JN; Crist TO
[Ad] Endereço:Department of Biology, Miami University, Oxford, OH.
[Ti] Título:The Effects of Dispersal and Predator Density on Prey Survival in an Insect-Red Clover Metacommunity.
[So] Source:J Insect Sci;18(1), 2018 Jan 01.
[Is] ISSN:1536-2442
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Trophic interactions are often studied within habitat patches, but among-patch dispersal of individuals may influence local patch dynamics. Metacommunity concepts incorporate the effects of dispersal on local and community dynamics. There are few experimental tests of metacommunity theory using insects compared to those conducted in microbial microcosms. Using connected experimental mesocosms, we varied the density of the leafhopper Agallia constricta Van Duzee (Homoptera: Cicadellidae) and a generalist insect predator, the damsel bug (Nabis spp., Heteroptera: Nabidae), to determine the effects of conspecific and predator density and varying the time available to dispersal among mesocosms on predation rates, dispersal rates, and leafhopper survival. Conspecific and damsel bug density did not affect dispersal rates in leafhoppers, but this may be due to leafhoppers' aversion to leaving the host plants or the connecting tubes between mesocosms hindering leafhopper movement. Leafhopper dispersal was higher in high-dispersal treatments. Survival rates of A. constricta were also lowest in treatments where dispersal was not limited. This is one of the first experimental studies to vary predator density and the time available to dispersal. Our results indicate that dispersal is the key to understanding short-term processes such as prey survival in predator-prey metacommunities. Further work is needed to determine how dispersal rates influence persistence of communities in multigenerational studies.
[Mh] Termos MeSH primário: Cadeia Alimentar
Heterópteros
[Mh] Termos MeSH secundário: Animais
Feminino
Densidade Demográfica
Trifolium
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180221
[Lr] Data última revisão:
180221
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180105
[St] Status:MEDLINE
[do] DOI:10.1093/jisesa/iex100


  2 / 911 MEDLINE  
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[PMID]:29210242
[Au] Autor:Köhl L; Oehl F; van der Heijden MGA
[Ti] Título:Agricultural practices indirectly influence plant productivity and ecosystem services through effects on soil biota.
[So] Source:Ecol Appl;24(7):1842-53, 2014.
[Is] ISSN:1051-0761
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:It is well established that agricultural practices alter the composition and diversity of soil microbial communities. However, the impact of changing soil microbial communities on the functioning of the agroecosystems is still poorly understood. Earlier work showed that soil tillage drastically altered microbial community composition. Here we tested, using an experimental grassland (Lolium, Trifolium, Plantago) as a model system, whether soil microbial communities from conventionally tilled (CT) and non-tilled (NT) soils have different influences on plant productivity and nutrient acquisition. We specifically focus on arbuscular mycorrhizal fungi (AMF), as they are a group of beneficial soil fungi that can promote plant productivity and ecosystem functioning and are also strongly affected by tillage management. Soil microbial communities from CT and NT soils varied greatly in their effects on the grassland communities. Communities from CT soil increased overall biomass production more than soil communities from NT soil. This effect was mainly due to a significant growth promotion of Trifolium by CT microorganisms. In contrast to CT soil inoculum, NT soil inoculum increased plant phosphorus concentration and total plant P content, demonstrating that the soil microbial communities from NT fields enhance P uptake. Differences in AM fungal community composition resulting, for instance, in twofold greater hyphal length in NT soil communities when compared to CT, are the most likely explanation for the different plant responses to CT and NT soil inocula. A range of field studies have shown that plant P uptake increases when farmers change to conservation tillage or direct seeding. Our results indicate that this enhanced P uptake results from enhanced hyphal length and an altered AM fungal community. Our results further demonstrate that agricultural management practices indirectly influence ecosystem services and plant community structure through effects on soil biota.
[Mh] Termos MeSH primário: Agricultura
Lolium/fisiologia
Micorrizas/fisiologia
Plantago/fisiologia
Microbiologia do Solo
Trifolium/fisiologia
[Mh] Termos MeSH secundário: Animais
Asteraceae/microbiologia
Asteraceae/fisiologia
Biomassa
Ecossistema
Lolium/microbiologia
Raízes de Plantas/crescimento & desenvolvimento
Raízes de Plantas/microbiologia
Plantago/microbiologia
Trifolium/microbiologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180108
[Lr] Data última revisão:
180108
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171207
[St] Status:MEDLINE


  3 / 911 MEDLINE  
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[PMID]:28950025
[Au] Autor:Poblaciones MJ; Damon P; Rengel Z
[Ad] Endereço:Department of Agronomy and Forest Environment Engineering, University of Extremadura, Badajoz, Spain.
[Ti] Título:Foliar zinc biofortification effects in Lolium rigidum and Trifolium subterraneum grown in cadmium-contaminated soil.
[So] Source:PLoS One;12(9):e0185395, 2017.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Zinc (Zn) is an important micronutrient that can alleviate cadmium (Cd) toxicity to plants and limit Cd entry into the food chain. However, little is known about the Zn-Cd interactions in pasture plants. We characterized the effects of foliar Zn application and Cd uptake by ryegrass (Lolium rigidum L.) and clover (Trifolium subterraneum L.) grown on Cd-contaminated soils; all combinations of foliar Zn applications (0, 0.25 and 0.5% (w/v) ZnSO4·7H2O) and soil Cd concentrations (0, 2.5 and 5 mg Cd kg-1) were tested. For both plant species, soil concentrations of DTPA-extractable Cd and Zn increased with an increase in the Cd and Zn treatments, respectively. Compared with L. rigidum, T. subterraneum accumulated, respectively, 3.3- and 4.1-fold more Cd in the 2.5-Cd and 5-Cd treatments and about 1.3-, 2.3- and 2.8-fold more Zn in the No-Zn, 0.25-Zn and 0.5-Zn treatments. Also, DTPA-Zn concentration was higher in soil after T. subterraneum than L. rigidum growth regardless of Zn applications. Foliar application of 0.25% (w/v) Zn significantly decreased the total Cd concentration in shoots of both species grown in the Cd-contaminated soil and ameliorated the adverse effects of Cd exposure on root growth, particularly in T. subterraneum.
[Mh] Termos MeSH primário: Cádmio/toxicidade
Lolium/metabolismo
Folhas de Planta/metabolismo
Poluentes do Solo/toxicidade
Trifolium/metabolismo
Zinco/metabolismo
[Mh] Termos MeSH secundário: Lolium/crescimento & desenvolvimento
Trifolium/crescimento & desenvolvimento
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Soil Pollutants); 00BH33GNGH (Cadmium); J41CSQ7QDS (Zinc)
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171019
[Lr] Data última revisão:
171019
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170927
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0185395


  4 / 911 MEDLINE  
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[PMID]:28777978
[Au] Autor:Kolodziejczyk-Czepas J; Krzyzanowska-Kowalczyk J; Sieradzka M; Nowak P; Stochmal A
[Ad] Endereço:Department of General Biochemistry, Faculty of Biology and Environmental Protection, University of Lodz, Pomorska 141/143, 90-236 Lodz, Poland. Electronic address: joanna.kolodziejczyk@biol.uni.lodz.pl.
[Ti] Título:Clovamide and clovamide-rich extracts of three Trifolium species as antioxidants and moderate antiplatelet agents in vitro.
[So] Source:Phytochemistry;143:54-63, 2017 Nov.
[Is] ISSN:1873-3700
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:This in vitro study provides a new insight into the phytochemical, antioxidant, antiplatelet and cytotoxic profiles of commercial trans-clovamide and clovamide-rich extracts, isolated from aerial parts of three Trifolium species (i.e. T. clypeatum L., T. obscurum Savi and T. squarrosum L.). Under inorganic experimental conditions, the EC for the investigated substances varied between 4.87 (clovamide) and 7.91 µg/ml (T. clypeatum) according to the DPPH assay. The most effective 1 mM ONOO scavenger was clovamide (IC = 19.29 µg/ml), and the weakest was the T. obsucurum extract (IC = 41.79 µg/ml). The antioxidant action of the examined substances (1-50 µg/ml) was also evaluated in blood plasma (under 100 µM ONOO -induced oxidative stress) using 3-nitrotyrosine, protein thiol groups, lipid hydroperoxides and thiobarbituric acid-reactive substances as biomarkers. All examined substances were more effective in limiting the oxidative damage to blood plasma components than the nitrative damage. Their anti-nitrative action was statistically significant only at the highest concentration (50 µg/ml). Measurements of platelet adhesion and aggregation found the compounds to have moderate antiplatelet properties of up to 20% inhibition of platelet adhesion at concentrations of 1-5 µg/ml. Additionally, clovamide and Trifolium extracts demonstrated no cytotoxicity towards blood platelets or peripheral blood mononuclear cells.
[Mh] Termos MeSH primário: Antioxidantes/farmacologia
Trifolium/química
Tirosina/análogos & derivados
[Mh] Termos MeSH secundário: Plaquetas/efeitos dos fármacos
Seres Humanos
Leucócitos Mononucleares
Inibidores da Agregação de Plaquetas/farmacologia
Substâncias Reativas com Ácido Tiobarbitúrico/química
Trifolium/genética
Tirosina/farmacologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Antioxidants); 0 (Platelet Aggregation Inhibitors); 0 (Thiobarbituric Acid Reactive Substances); 3604-79-3 (3-nitrotyrosine); 42HK56048U (Tyrosine); 53755-03-6 (clovamide)
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171002
[Lr] Data última revisão:
171002
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170805
[St] Status:MEDLINE


  5 / 911 MEDLINE  
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[PMID]:28768651
[Au] Autor:Lambert MNT; Thybo CB; Lykkeboe S; Rasmussen LM; Frette X; Christensen LP; Jeppesen PB
[Ad] Endereço:Department of Clinical Medicine, Aarhus University, Aarhus, Denmark.
[Ti] Título:Combined bioavailable isoflavones and probiotics improve bone status and estrogen metabolism in postmenopausal osteopenic women: a randomized controlled trial.
[So] Source:Am J Clin Nutr;106(3):909-920, 2017 Sep.
[Is] ISSN:1938-3207
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Female age-related estrogen deficiency increases the risk of osteoporosis, which can be effectively treated with the use of hormone replacement therapy. However, hormone replacement therapy is demonstrated to increase cancer risk. Bioavailable isoflavones with selective estrogen receptor affinity show potential to prevent and treat osteoporosis while minimizing or eliminating carcinogenic side effects. In this study, we sought to determine the beneficial effects of a bioavailable isoflavone and probiotic treatment against postmenopausal osteopenia. We used a novel red clover extract (RCE) rich in isoflavone aglycones and probiotics to concomitantly promote uptake and a favorable intestinal bacterial profile to enhance isoflavone bioavailability. This was a 12-mo, double-blind, parallel design, placebo-controlled, randomized controlled trial of 78 postmenopausal osteopenic women supplemented with calcium (1200 mg/d), magnesium (550 mg/d), and calcitriol (25 µg/d) given either RCE (60 mg isoflavone aglycones/d and probiotics) or a masked placebo [control (CON)]. RCE significantly attenuated bone mineral density (BMD) loss at the L2-L4 lumbar spine vertebra ( < 0.05), femoral neck ( < 0.01), and trochanter ( < 0.01) compared with CON (-0.99% and -2.2%; -1.04% and -3.05%; and -0.67% and -2.79, respectively). Plasma concentrations of collagen type 1 cross-linked C-telopeptide was significantly decreased in the RCE group ( < 0.05) compared with CON (-9.40% and -6.76%, respectively). RCE significantly elevated the plasma isoflavone concentration ( < 0.05), the urinary 2-hydroxyestrone (2-OH) to 16α-hydroxyestrone (16α-OH) ratio ( < 0.05), and equol-producer status ( < 0.05) compared with CON. RCE had no significant effect on other bone turnover biomarkers. Self-reported diet and physical activity were consistent and differences were nonsignificant between groups throughout the study. RCE was well tolerated with no adverse events. Twice daily RCE intake over 1 y potently attenuated BMD loss caused by estrogen deficiency, improved bone turnover, promoted a favorable estrogen metabolite profile (2-OH:16α-OH), and stimulated equol production in postmenopausal women with osteopenia. RCE intake combined with supplementation (calcium, magnesium, and calcitriol) was more effective than supplementation alone. This trial was registered at clinicaltrials.gov as NCT02174666.
[Mh] Termos MeSH primário: Densidade Óssea/efeitos dos fármacos
Doenças Ósseas Metabólicas/tratamento farmacológico
Remodelação Óssea/efeitos dos fármacos
Osso e Ossos/efeitos dos fármacos
Estrogênios/metabolismo
Isoflavonas/uso terapêutico
Probióticos/uso terapêutico
[Mh] Termos MeSH secundário: Disponibilidade Biológica
Conservadores da Densidade Óssea/farmacologia
Conservadores da Densidade Óssea/uso terapêutico
Doenças Ósseas Metabólicas/metabolismo
Osso e Ossos/metabolismo
Colágeno Tipo I/sangue
Método Duplo-Cego
Combinação de Medicamentos
Estrogênios/deficiência
Feminino
Microbioma Gastrointestinal
Seres Humanos
Intestinos/efeitos dos fármacos
Intestinos/metabolismo
Intestinos/microbiologia
Isoflavonas/sangue
Isoflavonas/farmacocinética
Isoflavonas/farmacologia
Meia-Idade
Osteoporose Pós-Menopausa/metabolismo
Osteoporose Pós-Menopausa/prevenção & controle
Peptídeos/sangue
Fitoterapia
Extratos Vegetais/farmacologia
Extratos Vegetais/uso terapêutico
Moduladores Seletivos de Receptor Estrogênico/farmacologia
Moduladores Seletivos de Receptor Estrogênico/uso terapêutico
Trifolium/química
[Pt] Tipo de publicação:JOURNAL ARTICLE; RANDOMIZED CONTROLLED TRIAL
[Nm] Nome de substância:
0 (Bone Density Conservation Agents); 0 (Collagen Type I); 0 (Drug Combinations); 0 (Estrogens); 0 (Isoflavones); 0 (Peptides); 0 (Plant Extracts); 0 (Selective Estrogen Receptor Modulators); 0 (collagen type I trimeric cross-linked peptide)
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170913
[Lr] Data última revisão:
170913
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:170804
[St] Status:MEDLINE
[do] DOI:10.3945/ajcn.117.153353


  6 / 911 MEDLINE  
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[PMID]:28591213
[Au] Autor:Miller-Struttmann NE; Heise D; Schul J; Geib JC; Galen C
[Ad] Endereço:Biological Sciences Department, Webster University, St. Louis, Missouri, United States of America.
[Ti] Título:Flight of the bumble bee: Buzzes predict pollination services.
[So] Source:PLoS One;12(6):e0179273, 2017.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Multiple interacting factors drive recent declines in wild and managed bees, threatening their pollination services. Widespread and intensive monitoring could lead to more effective management of wild and managed bees. However, tracking their dynamic populations is costly. We tested the effectiveness of an inexpensive, noninvasive and passive acoustic survey technique for monitoring bumble bee behavior and pollination services. First, we assessed the relationship between the first harmonic of the flight buzz (characteristic frequency) and pollinator functional traits that influence pollination success using flight cage experiments and a literature search. We analyzed passive acoustic survey data from three locations on Pennsylvania Mountain, Colorado to estimate bumble bee activity. We developed an algorithm based on Computational Auditory Scene Analysis that identified and quantified the number of buzzes recorded in each location. We then compared visual and acoustic estimates of bumble bee activity. Using pollinator exclusion experiments, we tested the power of buzz density to predict pollination services at the landscape scale for two bumble bee pollinated alpine forbs (Trifolium dasyphyllum and T. parryi). We found that the characteristic frequency was correlated with traits known to affect pollination efficacy, explaining 30-52% of variation in body size and tongue length. Buzz density was highly correlated with visual estimates of bumble bee density (r = 0.97), indicating that acoustic signals are predictive of bumble bee activity. Buzz density predicted seed set in two alpine forbs when bumble bees were permitted access to the flowers, but not when they were excluded from visiting. Our results indicate that acoustic signatures of flight can be deciphered to monitor bee activity and pollination services to bumble bee pollinated plants. We propose that applications of this technique could assist scientists and farmers in rapidly detecting and responding to bee population declines.
[Mh] Termos MeSH primário: Abelhas/fisiologia
Flores/fisiologia
Polinização/fisiologia
Vocalização Animal/fisiologia
[Mh] Termos MeSH secundário: Animais
Colorado
Ecossistema
Voo Animal/fisiologia
Trifolium/fisiologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170913
[Lr] Data última revisão:
170913
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170608
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0179273


  7 / 911 MEDLINE  
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[PMID]:28543850
[Au] Autor:Summers EL; Cumming MH; Oulavallickal T; Roberts NJ; Arcus VL
[Ad] Endereço:School of Science, University of Waikato, Private Bag 3105, Hamilton, 3240, New Zealand.
[Ti] Título:Structures and kinetics for plant nucleoside triphosphate diphosphohydrolases support a domain motion catalytic mechanism.
[So] Source:Protein Sci;26(8):1627-1638, 2017 Aug.
[Is] ISSN:1469-896X
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Extracellular nucleoside triphosphate diphosphohydrolases (NTPDases) are enzymes that hydrolyze extracellular nucleotides to the respective monophosphate nucleotides. In the past 20 years, NTPDases belonging to mammalian, parasitic and prokaryotic domains of life have been discovered, cloned and characterized. We reveal the first structures of NTPDases from the legume plant species Trifolium repens (7WC) and Vigna unguiculata subsp. cylindrica (DbLNP). Four crystal structures of 7WC and DbLNP were determined at resolutions between 1.9 and 2.6 Å. For 7WC, structures were determined for an -apo form (1.89 Å) and with the product AMP (2.15 Å) and adenine and phosphate (1.76 Å) bound. For DbLNP, a structure was solved with phosphate and manganese bound (2.60 Å). Thorough kinetic data and analysis is presented. The structure of 7WC and DbLNP reveals that these NTPDases can adopt two conformations depending on the molecule and co-factor bound in the active site. A central hinge region creates a "butterfly-like" motion of the domains that reduces the width of the inter-domain active site cleft upon molecule binding. This phenomenon has been previously described in Rattus norvegicus and Legionella pneumophila NTPDaseI and Toxoplasma gondii NTPDaseIII suggesting a common catalytic mechanism across the domains of life.
[Mh] Termos MeSH primário: Monofosfato de Adenosina/química
Trifosfato de Adenosina/química
Apirase/química
Proteínas de Plantas/química
Trifolium/química
Vigna/química
[Mh] Termos MeSH secundário: Monofosfato de Adenosina/metabolismo
Trifosfato de Adenosina/metabolismo
Sequência de Aminoácidos
Animais
Apirase/genética
Apirase/metabolismo
Domínio Catalítico
Clonagem Molecular
Cristalografia por Raios X
Escherichia coli/genética
Escherichia coli/metabolismo
Expressão Gênica
Isoenzimas/química
Isoenzimas/genética
Isoenzimas/metabolismo
Cinética
Legionella pneumophila/química
Legionella pneumophila/enzimologia
Manganês/química
Manganês/metabolismo
Modelos Moleculares
Fosfatos/química
Fosfatos/metabolismo
Proteínas de Plantas/genética
Proteínas de Plantas/metabolismo
Ligação Proteica
Conformação Proteica em alfa-Hélice
Conformação Proteica em Folha beta
Domínios e Motivos de Interação entre Proteínas
Ratos
Proteínas Recombinantes/química
Proteínas Recombinantes/genética
Proteínas Recombinantes/metabolismo
Alinhamento de Sequência
Homologia de Sequência de Aminoácidos
Especificidade por Substrato
Toxoplasma/química
Toxoplasma/enzimologia
Trifolium/enzimologia
Vigna/enzimologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Isoenzymes); 0 (Phosphates); 0 (Plant Proteins); 0 (Recombinant Proteins); 415SHH325A (Adenosine Monophosphate); 42Z2K6ZL8P (Manganese); 8L70Q75FXE (Adenosine Triphosphate); EC 3.6.1.5 (Apyrase)
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170824
[Lr] Data última revisão:
170824
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170526
[St] Status:MEDLINE
[do] DOI:10.1002/pro.3199


  8 / 911 MEDLINE  
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[PMID]:28482175
[Au] Autor:Huang Y; Huang J; Song Y; Liu H
[Ad] Endereço:Engineering Research Center of Eco-environment in Three Gorges Reservoir Region, Ministry of Education, China Three Gorges University, Yichang 443002, PR China. Electronic address: chem_ctgu@126.com.
[Ti] Título:Use of selenium to alleviate naphthalene induced oxidative stress in Trifolium repens L.
[So] Source:Ecotoxicol Environ Saf;143:1-5, 2017 Sep.
[Is] ISSN:1090-2414
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:Polycyclic aromatic hydrocarbons (PAHs) are among the most dangerous of environmental contaminants, due to their toxicity, carcinogenicity and mutagenicity. This study investigated the use of selenium (Se) to protect plants from the toxic effects of naphthalene (NPH). Exposing Trifolium repens L. (white clover) to a high concentration of NPH (soil spiked to 500mgkg ) for 60 d significantly decreased biomass, CO assimilation rate (Pn), stomatal conductance (Gs) and intercellular CO concentration (Ci), while inducing production of H O and malondialdehyde (MDA). Application of Se (soil spiked to 0.5mgkg ) to plants exposed to NPH clearly protected the plants; biomass, Pn, Gs and Ci were significantly higher and contents of MDA and H O decreased. The protection provided to Trifolium repens L. by Se is attributed primarily to an increase in photosynthesis and a decrease in oxidative stress. This study demonstrates that a low concentration of Se protects plants against oxidative stress induced by NPH and can provide a means for improving phytoremediation in PAHs contaminated soils.
[Mh] Termos MeSH primário: Naftalenos/toxicidade
Estresse Oxidativo/efeitos dos fármacos
Selênio/farmacologia
Poluentes do Solo/toxicidade
Trifolium/efeitos dos fármacos
[Mh] Termos MeSH secundário: Biodegradação Ambiental
Biomassa
Relação Dose-Resposta a Droga
Peróxido de Hidrogênio/metabolismo
Malondialdeído/metabolismo
Fotossíntese/efeitos dos fármacos
Solo/química
Trifolium/metabolismo
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Naphthalenes); 0 (Soil); 0 (Soil Pollutants); 2166IN72UN (naphthalene); 4Y8F71G49Q (Malondialdehyde); BBX060AN9V (Hydrogen Peroxide); H6241UJ22B (Selenium)
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171116
[Lr] Data última revisão:
171116
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170509
[St] Status:MEDLINE


  9 / 911 MEDLINE  
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[PMID]:28420109
[Au] Autor:Skladanka J; Adam V; Zitka O; Mlejnkova V; Kalhotka L; Horky P; Konecna K; Hodulikova L; Knotova D; Balabanova M; Slama P; Skarpa P
[Ad] Endereço:Faculty of AgriSciences, Mendel University in Brno, Zemedelska 1, 61300 Brno, Czech Republic. jiri.skladanka@mendelu.cz.
[Ti] Título:Comparison of Biogenic Amines and Mycotoxins in Alfalfa and Red Clover Fodder Depending on Additives.
[So] Source:Int J Environ Res Public Health;14(4), 2017 Apr 14.
[Is] ISSN:1660-4601
[Cp] País de publicação:Switzerland
[La] Idioma:eng
[Ab] Resumo:In the production of fermented feed, each crop can be contaminated with a variety of microorganisms that may produce natural pollutants. Biogenic amines, mycotoxins, and undesirable organic acids can decrease health feed safety. The aim of this study was to compare the counts of microorganisms, levels of biogenic amines, and the mycotoxins in forage legumes, and also to compare the occurrence of microorganisms and levels of mycotoxins in green fodder and subsequently produced silage and the influence of additives on the content of natural harmful substances in silage. The experimental plot was located in Troubsko and Vatín, in the Czech Republic. Two varieties of and one variety of were compared. Green fodder and subsequently produced silage reaching up to 23% of dry matter were evaluated and prepared using a bio-enzymatic additive and a chemical additive. Green fodder of was more contaminated by than fodder. The obvious difference was determined by the quality of silage leachate. The silage prepared from fodder was more contaminated with butyric acid. Fungi were present in higher counts in the anaerobic environment of green fodder and contaminated it with zearalenone and deoxynivalenol. Lower counts of fungi were found in silage, although the zearalenone content did not change. Lower content of deoxynivalenol was detected in silage, compared with green fodder. Silages treated with a chemical additive were found not to contain butyric acid. Lower ethanol content was determined, and the tendency to reduce the risk of biogenic amines occurrence was evident. The additives proved to have no influence on the content of mycotoxins.
[Mh] Termos MeSH primário: Ração Animal/microbiologia
Aminas Biogênicas/química
Aditivos Alimentares/farmacologia
Contaminação de Alimentos/prevenção & controle
Medicago sativa/química
Micotoxinas/química
Trifolium/química
[Mh] Termos MeSH secundário: Animais
República Tcheca
Fermentação
Medicago sativa/microbiologia
Silagem/análise
Silagem/microbiologia
Trifolium/microbiologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Biogenic Amines); 0 (Food Additives); 0 (Mycotoxins)
[Em] Mês de entrada:1705
[Cu] Atualização por classe:170530
[Lr] Data última revisão:
170530
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170420
[St] Status:MEDLINE


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[PMID]:28160855
[Au] Autor:Myers SP; Vigar V
[Ad] Endereço:NatMed-Research Unit, Division of Research, Southern Cross University, Military Rd., Lismore, NSW 2480, Australia. Electronic address: stephen.myers@scu.edu.au.
[Ti] Título:Effects of a standardised extract of Trifolium pratense (Promensil) at a dosage of 80mg in the treatment of menopausal hot flushes: A systematic review and meta-analysis.
[So] Source:Phytomedicine;24:141-147, 2017 Jan 15.
[Is] ISSN:1618-095X
[Cp] País de publicação:Germany
[La] Idioma:eng
[Ab] Resumo:OBJECTIVE: To critically assess the evidence for a specific standardised extract of Trifolium pratense isoflavones (Promensil) at a dosage of 80mg/day in the treatment of menopausal hot flushes. DATA SOURCES: Systematic literature searches were performed in Medline, Scopus, CINAHL Plus, Cochrane, AMED and InforRMIT and citations obtained from 1996 to March 2016. Reference lists were checked; corresponding authors contacted and the grey literature searched for additional publications. REVIEW METHODS: Studies were selected according to predefined inclusion and exclusion criteria. All randomised clinical trials of a specific standardised extract of Trifolium pratense isoflavones (Promensil) used as a mono-component at 80mg/day and measuring vasomotor symptoms were included. The data extraction and quality assessment were performed independently by one reviewer and validated by a second with any disagreements being settled by discussion. Weighted mean differences and 95% confidence intervals were calculated for continuous data using the fixed-effects model. RESULTS: Twenty potentially relevant papers were identified, with only five studies meeting the inclusion criteria. The meta-analysis demonstrated a statistical and clinically relevant reduction in hot flush frequency in the active treatment group compared to placebo. Weighted mean difference 3.63 hot flushes per day: [95% CI 2.70-4.56]; p˂0.00001). Due to a lack of homogeneity a priori defined sub-group analyses were performed demonstrating a substantive difference between cross-over and parallel-arm clinical trial designs. CONCLUSION: There is evidence for a statistical and clinically significant benefit for using a specific standardised extract of red clover isoflavones (Promensil) at 80mg/day for treating hot flushes in menopausal women across the 3 studies included in the meta-analysis. The preparation was safe over the short-term duration of the studies (3 months).
[Mh] Termos MeSH primário: Fogachos/tratamento farmacológico
Isoflavonas/uso terapêutico
Menopausa/fisiologia
Extratos Vegetais/uso terapêutico
Trifolium/química
[Mh] Termos MeSH secundário: Relação Dose-Resposta a Droga
Feminino
Seres Humanos
Fitoterapia
Fatores de Tempo
[Pt] Tipo de publicação:JOURNAL ARTICLE; META-ANALYSIS; REVIEW
[Nm] Nome de substância:
0 (Isoflavones); 0 (Plant Extracts)
[Em] Mês de entrada:1704
[Cu] Atualização por classe:170817
[Lr] Data última revisão:
170817
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170206
[St] Status:MEDLINE



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