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Pesquisa : B01.650.940.800.575.912.250.456.937.844 [Categoria DeCS]
Referências encontradas : 79 [refinar]
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[PMID]:28085077
[Au] Autor:Carvalho Junior AR; Vieira IJ; Carvalho MG; Braz-Filho R; S Lima MA; Ferreira RO; José Maria E; Oliveira DB
[Ad] Endereço:Laboratório de Ciências Químicas, CCT, Universidade Estadual do Norte Fluminense Darcy Ribeiro, Campos dos Goytacazes, RJ 28013-602, Brazil. almir@uenf.br.
[Ti] Título:C-NMR Spectral Data of Alkaloids Isolated from Psychotria Species (Rubiaceae).
[So] Source:Molecules;22(1), 2017 Jan 11.
[Is] ISSN:1420-3049
[Cp] País de publicação:Switzerland
[La] Idioma:eng
[Ab] Resumo:The genus (Rubiaceae) comprises more than 2000 species, mainly found in tropical and subtropical forests. Several studies have been conducted concerning their chemical compositions, showing that this genus is a potential source of alkaloids. At least 70 indole alkaloids have been identified from this genus so far. This review aimed to compile C-NMR data of alkaloids isolated from the genus as well as describe the main spectral features of different skeletons.
[Mh] Termos MeSH primário: Alcaloides de Indol/química
Monoterpenos/química
Psychotria/química
Quinazolinas/química
[Mh] Termos MeSH secundário: Isótopos de Carbono
Alcaloides de Indol/isolamento & purificação
Espectroscopia de Ressonância Magnética
Estrutura Molecular
Monoterpenos/isolamento & purificação
Quinazolinas/isolamento & purificação
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Nm] Nome de substância:
0 (Carbon Isotopes); 0 (Indole Alkaloids); 0 (Monoterpenes); 0 (Quinazolines)
[Em] Mês de entrada:1705
[Cu] Atualização por classe:170515
[Lr] Data última revisão:
170515
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170114
[St] Status:MEDLINE


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[PMID]:28006906
[Au] Autor:Matsuura HN; Poth AG; Yendo AC; Fett-Neto AG; Craik DJ
[Ad] Endereço:Center for Biotechnology and Department of Botany, Federal University of Rio Grande do Sul , Porto Alegre, RS, Brazil.
[Ti] Título:Isolation and Characterization of Cyclotides from Brazilian Psychotria: Significance in Plant Defense and Co-occurrence with Antioxidant Alkaloids.
[So] Source:J Nat Prod;79(12):3006-3013, 2016 Dec 23.
[Is] ISSN:1520-6025
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Plants from the genus Psychotria include species bearing cyclotides and/or alkaloids. The elucidation of factors affecting the metabolism of these molecules as well as their activities may help to understand their ecological function. In the present study, high concentrations of antioxidant indole alkaloids were found to co-occur with cyclotides in Psychotria leiocarpa and P. brachyceras. The concentrations of the major cyclotides and alkaloids in P. leiocarpa and P. brachyceras were monitored following herbivore- and pathogen-associated challenges, revealing a constitutive, phytoanticipin-like accumulation pattern. Psyleio A, the most abundant cyclotide found in the leaves of P. leiocarpa, and also found in P. brachyceras leaves, exhibited insecticidal activity against Helicoverpa armigera larvae. Addition of ethanol in the vehicle for peptide solubilization in larval feeding trials proved deleterious to insecticidal activity and resulted in increased rates of larval survival in treatments containing indole alkaloids. This suggests that plant alkaloids ingested by larvae might contribute to herbivore oxidative stress detoxification, corroborating, in a heterologous system with artificial oxidative stress stimulation, the antioxidant efficiency of Psychotria alkaloids previously observed in planta. Overall, the present study reports data for eight novel cyclotides, the identification of P. leiocarpa as a cyclotide-bearing species, and the absence of these peptides in P. umbellata.
[Mh] Termos MeSH primário: Ciclotídeos/isolamento & purificação
Alcaloides de Indol/isolamento & purificação
Inseticidas/isolamento & purificação
Inseticidas/farmacologia
Psychotria/química
[Mh] Termos MeSH secundário: Sequência de Aminoácidos
Animais
Antioxidantes/química
Brasil
Ciclotídeos/análise
Ciclotídeos/química
Ciclotídeos/farmacologia
Herbivoria
Alcaloides de Indol/análise
Alcaloides de Indol/química
Alcaloides de Indol/farmacologia
Inseticidas/química
Larva/efeitos dos fármacos
Lepidópteros/efeitos dos fármacos
Dados de Sequência Molecular
Estrutura Molecular
Estresse Oxidativo
Folhas de Planta/química
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Antioxidants); 0 (Cyclotides); 0 (Indole Alkaloids); 0 (Insecticides)
[Em] Mês de entrada:1705
[Cu] Atualização por classe:170503
[Lr] Data última revisão:
170503
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161224
[St] Status:MEDLINE
[do] DOI:10.1021/acs.jnatprod.6b00492


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[PMID]:27511709
[Au] Autor:Klein-Júnior LC; Viaene J; Tuenter E; Salton J; Gasper AL; Apers S; Andries JP; Pieters L; Henriques AT; Vander Heyden Y
[Ad] Endereço:Department of Analytical Chemistry and Pharmaceutical Technology, Center for Pharmaceutical Research (CePhaR), Vrije Universiteit Brussel - VUB, Laarbeeklaan 103, B-1090 Brussels, Belgium; Laboratory of Pharmacognosy and Quality Control of Phytomedicines, Faculty of Pharmacy, Universidade Federal do
[Ti] Título:The use of chemometrics to study multifunctional indole alkaloids from Psychotria nemorosa (Palicourea comb. nov.). Part II: Indication of peaks related to the inhibition of butyrylcholinesterase and monoamine oxidase-A.
[So] Source:J Chromatogr A;1463:71-80, 2016 Sep 09.
[Is] ISSN:1873-3778
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:Psychotria nemorosa is chemically characterized by indole alkaloids and displays significant inhibitory activity on butyrylcholinesterase (BChE) and monoamine oxidase-A (MAO-A), both enzymes related to neurodegenerative disorders. In the present study, 43 samples of P. nemorosa leaves were extracted and fractionated in accordance to previously optimized methods (see Part I). These fractions were analyzed by means of UPLC-DAD and assayed for their BChE and MAO-A inhibitory potencies. The chromatographic fingerprint data was first aligned using correlation optimized warping and Principal Component Analysis to explore the data structure was performed. Multivariate calibration techniques, namely Partial Least Squares (PLS1), PLS2 and Orthogonal Projections to Latent Structure (O-PLS1), were evaluated for modelling the activities as a function of the fingerprints. Since the best results were obtained with O-PLS1 model (RMSECV=9.3 and 3.3 for BChE and MAO-A, respectively), the regression coefficients of the model were analyzed and plotted relative to the original fingerprints. Four peaks were indicated as multifunctional compounds, with the capacity to impair both BChE and MAO-A activities. In order to confirm these results, a semi-prep HPLC technique was used and a fraction containing the four peaks was purified and evaluated in vitro. It was observed that the fraction exhibited an IC50 of 2.12µgmL(-1) for BChE and 1.07µgmL(-1) for MAO-A. These results reinforce the prediction obtained by O-PLS1 modelling.
[Mh] Termos MeSH primário: Butirilcolinesterase/metabolismo
Fracionamento Químico/métodos
Inibidores da Colinesterase/análise
Alcaloides de Indol/isolamento & purificação
Alcaloides de Indol/farmacologia
Inibidores da Monoaminoxidase/análise
Monoaminoxidase/metabolismo
Psychotria/química
[Mh] Termos MeSH secundário: Calibragem
Inibidores da Colinesterase/farmacologia
Cromatografia Líquida de Alta Pressão
Concentração Inibidora 50
Análise dos Mínimos Quadrados
Modelos Lineares
Inibidores da Monoaminoxidase/farmacologia
Análise de Componente Principal
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Cholinesterase Inhibitors); 0 (Indole Alkaloids); 0 (Monoamine Oxidase Inhibitors); EC 1.4.3.4 (Monoamine Oxidase); EC 3.1.1.8 (Butyrylcholinesterase)
[Em] Mês de entrada:1612
[Cu] Atualização por classe:171116
[Lr] Data última revisão:
171116
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160812
[St] Status:MEDLINE


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[PMID]:27473512
[Au] Autor:Klein-Júnior LC; Viaene J; Salton J; Koetz M; Gasper AL; Henriques AT; Vander Heyden Y
[Ad] Endereço:Department of Analytical Chemistry and Pharmaceutical Technology, Center for Pharmaceutical Research (CePhaR), Vrije Universiteit Brussel-VUB, Laarbeeklaan 103, B-1090 Brussels, Belgium; Laboratory of Pharmacognosy and Quality Control of Phytomedicines, Faculty of Pharmacy, Universidade Federal do R
[Ti] Título:The use of chemometrics to study multifunctional indole alkaloids from Psychotria nemorosa (Palicourea comb. nov.). Part I: Extraction and fractionation optimization based on metabolic profiling.
[So] Source:J Chromatogr A;1463:60-70, 2016 Sep 09.
[Is] ISSN:1873-3778
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:Extraction methods evaluation to access plants metabolome is usually performed visually, lacking a truthful method of data handling. In the present study the major aim was developing reliable time- and solvent-saving extraction and fractionation methods to access alkaloid profiling of Psychotria nemorosa leaves. Ultrasound assisted extraction was selected as extraction method. Determined from a Fractional Factorial Design (FFD) approach, yield, sum of peak areas, and peak numbers were rather meaningless responses. However, Euclidean distance calculations between the UPLC-DAD metabolic profiles and the blank injection evidenced the extracts are highly diverse. Coupled with the calculation and plotting of effects per time point, it was possible to indicate thermolabile peaks. After screening, time and temperature were selected for optimization, while plant:solvent ratio was set at 1:50 (m/v), number of extractions at one and particle size at ≤180µm. From Central Composite Design (CCD) results modeling heights of important peaks, previously indicated by the FFD metabolic profile analysis, time was set at 65min and temperature at 45°C, thus avoiding degradation. For the fractionation step, a solid phase extraction method was optimized by a Box-Behnken Design (BBD) approach using the sum of peak areas as response. Sample concentration was consequently set at 150mg/mL, % acetonitrile in dichloromethane at 40% as eluting solvent, and eluting volume at 30mL. Summarized, the Euclidean distance and the metabolite profiles provided significant responses for accessing P. nemorosa alkaloids, allowing developing reliable extraction and fractionation methods, avoiding degradation and decreasing the required time and solvent volume.
[Mh] Termos MeSH primário: Fracionamento Químico/métodos
Alcaloides de Indol/isolamento & purificação
Metaboloma
Metabolômica
Psychotria/química
Psychotria/metabolismo
Extração em Fase Sólida/métodos
[Mh] Termos MeSH secundário: Alcaloides de Indol/metabolismo
Folhas de Planta/química
Folhas de Planta/metabolismo
Solventes/química
Temperatura Ambiente
Fatores de Tempo
Ultrassom
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Indole Alkaloids); 0 (Solvents)
[Em] Mês de entrada:1612
[Cu] Atualização por classe:161230
[Lr] Data última revisão:
161230
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160731
[St] Status:MEDLINE


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[PMID]:27245635
[Au] Autor:Guzmán Q JA; Cordero RA
[Ad] Endereço:Programa de Posgrado en Biología, Sistema de Estudios de Posgrado, Universidad de Costa Rica, PO Box 2060 San Pedro, Costa Rica Laboratorio de Ecología Funcional y Ecosistemas Tropicales, Escuela de Ciencias Biológicas, Universidad Nacional de Costa Rica, PO Box 86-3000 Heredia, Costa Rica antguz06@gmail.com.
[Ti] Título:Neighbourhood structure and light availability influence the variations in plant design of shrubs in two cloud forests of different successional status.
[So] Source:Ann Bot;118(1):23-34, 2016 Jul.
[Is] ISSN:1095-8290
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:BACKGROUND AND AIMS: Plant design refers to the construction of the plant body or its constituent parts in terms of form and function. Although neighbourhood structure is recognized as a factor that limits plant survival and species coexistence, its relative importance in plant design is not well understood. We conducted field research to analyse how the surrounding environment of neighbourhood structure and related effects on light availability are associated with changes in plant design in two understorey plants (Palicourea padifolia and Psychotria elata) within two successional stages of a cloud forest in Costa Rica. METHODS: Features of plant neighbourhood physical structure and light availability, estimated using hemispherical photographs, were used as variables that reflect the surrounding environment. Measures of plant biomechanics, allometry, branching and plant slenderness were used as functional plant attributes that reflect plant design. We propose a framework using a partial least squares path model and used it to test this association. KEY RESULTS: The multidimensional response of plant design of these species suggests that decreases in the height-based factor of safety and increases in mechanical load and developmental stability are influenced by increases in maximum height of neighbours and a distance-dependence interference index more than neighbourhood plant density or neighbour aggregation. Changes in plant branching and slenderness are associated positively with light availability and negatively with canopy cover. CONCLUSIONS: Although it has been proposed that plant design varies according to plant density and light availability, we found that neighbour size and distance-dependence interference are associated with changes in biomechanics, allometry and branching, and they must be considered as key factors that contribute to the adaptation and coexistence of these plants in this highly diverse forest community.
[Mh] Termos MeSH primário: Florestas
Rubiaceae/fisiologia
[Mh] Termos MeSH secundário: Costa Rica
Ecossistema
Luz
Psychotria/anatomia & histologia
Psychotria/fisiologia
Rubiaceae/anatomia & histologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170816
[Lr] Data última revisão:
170816
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160602
[St] Status:MEDLINE
[do] DOI:10.1093/aob/mcw078


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[PMID]:27236700
[Au] Autor:Huang W; Yang YJ; Zhang JL; Hu H; Zhang SB
[Ad] Endereço:Key Laboratory of Tropical Forest Ecology, Xishuangbanna Tropical Botanical Garden, Chinese Academy of Sciences, Mengla, 666303, Yunnan, China.
[Ti] Título:PSI photoinhibition is more related to electron transfer from PSII to PSI rather than PSI redox state in Psychotria rubra.
[So] Source:Photosynth Res;129(1):85-92, 2016 Jul.
[Is] ISSN:1573-5079
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:Although it has been believed that wild-type plants are capable of protecting photosystem I (PSI) under high light, our previous study indicates that PSI is sensitive to high light in the shade-established tree species Psychotria rubra. However, the underlying physiological mechanisms are unclear. In this study, we examined the roles of electron transfer from PSII to PSI and PSI redox state in PSI photoinhibition in P. rubra by treatments with lincomycin (Lin), diuron (DCMU), and methyl viologen (MV). After exposure to 2000 µmol photons m(-2) s(-1) for 2 h, PSI activity decreased by 35, 29, 3, and 49 % in samples treated with H2O, Lin, DCMU, and MV, respectively. Meanwhile, the MV-treated samples showed higher P700 oxidation ratio than the H2O-treated samples, suggesting the PSI photoinhibition under high light was accompanied by high levels of P700 oxidation ratio. PSI photoinhibition was alleviated in the DCMU-treated samples but was accelerated in the MV-treated samples, suggesting that PSI photoinhibition in P. rubra was mainly controlled by electron transfer from PSII to PSI. Taking together, PSI photoinhibition is more related to electron transfer from PSII to PSI rather than PSI redox state in P. rubra, which is different from the mechanisms of PSI photoinhibition in Arabidopsis thaliana and cucumber.
[Mh] Termos MeSH primário: Complexo de Proteína do Fotossistema I/antagonistas & inibidores
Complexo de Proteína do Fotossistema II/antagonistas & inibidores
Psychotria/fisiologia
[Mh] Termos MeSH secundário: Diurona/farmacologia
Transporte de Elétrons
Lincomicina/farmacologia
Oxirredução
Paraquat/farmacologia
Fotossíntese/fisiologia
Psychotria/efeitos da radiação
Árvores
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Photosystem I Protein Complex); 0 (Photosystem II Protein Complex); 9I3SDS92WY (Diuron); BOD072YW0F (Lincomycin); PLG39H7695 (Paraquat)
[Em] Mês de entrada:1702
[Cu] Atualização por classe:171101
[Lr] Data última revisão:
171101
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160530
[St] Status:MEDLINE
[do] DOI:10.1007/s11120-016-0275-5


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[PMID]:27206020
[Au] Autor:Yang H; Zhang H; Yang C; Chen Y
[Ad] Endereço:School of Chemistry and Chemical Engineering, Yunnan Normal University, Kunming, 650500, P. R. China.
[Ti] Título:Chemical Constituents of Plants from the Genus Psychotria.
[So] Source:Chem Biodivers;13(7):807-20, 2016 Jul.
[Is] ISSN:1612-1880
[Cp] País de publicação:Switzerland
[La] Idioma:eng
[Ab] Resumo:Psychotria is a genus of ca. 1500 species in the family Rubiaceae. Up to now, 41 species of the Psychotria genus have been chemically investigated, and 159 compounds, including alkaloids of indole, quinoline and benzoquinolizidine type, terpenoids, steroids, phenolics and aliphatic compounds have been isolated. These compounds show potent bioactivities, such as antimicrobial, antiviral, and antiparasitic activities.
[Mh] Termos MeSH primário: Antibacterianos/isolamento & purificação
Antifúngicos/isolamento & purificação
Antineoplásicos Fitogênicos/isolamento & purificação
Antiparasitários/isolamento & purificação
Antivirais/isolamento & purificação
Psychotria/química
[Mh] Termos MeSH secundário: Alcaloides/química
Alcaloides/isolamento & purificação
Alcaloides/farmacologia
Animais
Antibacterianos/química
Antibacterianos/farmacologia
Antifúngicos/química
Antifúngicos/farmacologia
Antineoplásicos Fitogênicos/química
Antineoplásicos Fitogênicos/farmacologia
Antiparasitários/química
Antiparasitários/farmacologia
Antivirais/química
Antivirais/farmacologia
Bactérias/efeitos dos fármacos
Proliferação Celular/efeitos dos fármacos
Fungos/efeitos dos fármacos
Seres Humanos
Fenóis/química
Fenóis/isolamento & purificação
Fenóis/farmacologia
Esteroides/química
Esteroides/isolamento & purificação
Esteroides/farmacologia
Terpenos/química
Terpenos/isolamento & purificação
Terpenos/farmacologia
Vírus/efeitos dos fármacos
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Nm] Nome de substância:
0 (Alkaloids); 0 (Anti-Bacterial Agents); 0 (Antifungal Agents); 0 (Antineoplastic Agents, Phytogenic); 0 (Antiparasitic Agents); 0 (Antiviral Agents); 0 (Phenols); 0 (Steroids); 0 (Terpenes)
[Em] Mês de entrada:1701
[Cu] Atualização por classe:170117
[Lr] Data última revisão:
170117
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160521
[St] Status:MEDLINE
[do] DOI:10.1002/cbdv.201500259


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[PMID]:26963582
[Au] Autor:Liu L; Song CW; Khan A; Li XN; Yang XW; Cheng GG; Liu YP; Luo XD
[Ad] Endereço:a State Key Laboratory of Phytochemistry and Plant Resources in West China , Kunming Institute of Botany, Chinese Academy of Sciences , Kunming 650201 , China.
[Ti] Título:A potent antibacterial indole alkaloid from Psychotria pilifera.
[So] Source:J Asian Nat Prod Res;18(8):798-803, 2016 Aug.
[Is] ISSN:1477-2213
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:A new strychnine alkaloid, 16,17,19,20-tetrahydro-2,16-dehydro-18-deoxyisostrychnine (1), and fourteen known alkaloids were isolated from the leaves of Psychotria pilifera. Their structures were identified on the basis of extensive spectroscopic analysis, as well as by comparison with the reported spectroscopic data. The new alkaloid (1) exhibited potent antibacterial activity against Escherichia coli, equivalent to cefotaxime with MIC value of 0.781 µg/ml.
[Mh] Termos MeSH primário: Antibacterianos/isolamento & purificação
Antibacterianos/farmacologia
Psychotria/química
Estricnina/isolamento & purificação
Estricnina/farmacologia
[Mh] Termos MeSH secundário: Antibacterianos/química
Escherichia coli/efeitos dos fármacos
Testes de Sensibilidade Microbiana
Estrutura Molecular
Folhas de Planta/química
Staphylococcus aureus/efeitos dos fármacos
Estricnina/análogos & derivados
Estricnina/química
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (16,17,19,20-tetrahydro-2,16-dehydro-18-deoxyisostrychnine); 0 (Anti-Bacterial Agents); H9Y79VD43J (Strychnine)
[Em] Mês de entrada:1701
[Cu] Atualização por classe:170104
[Lr] Data última revisão:
170104
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160311
[St] Status:MEDLINE
[do] DOI:10.1080/10286020.2016.1158710


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[PMID]:26647632
[Au] Autor:Kowalczuk AP; Lozak A; Bachlinski R; Duszynski A; Sakowska J; Zjawiony JK
[Ti] Título:IDENTIFICATION CHALLENGES IN EXAMINATION OF COMMERCIAL PLANT MATERIAL OF PSYCHOTRIA VIRIDIS.
[So] Source:Acta Pol Pharm;72(4):747-55, 2015 Jul-Aug.
[Is] ISSN:0001-6837
[Cp] País de publicação:Poland
[La] Idioma:eng
[Ab] Resumo:Psychoria viridis (chacruna) is a hallucinogenic plant with psychoactive properties associated with the presence of N,N-dimethyltryptamine (DMT). This species is primarily known as an ingredient of the beverage Ayahuasca, but dry leaves are also smoked by recreational users. The plant is controlled in Poland and France and its proper identification poses many challenges due to the fact that genus Psychotria is relatively large and there are other species that are easily confused with chacruna. The aim of the present work was to develop an effective authentication procedure for the dried and shredded leaves of P. viridis, to be used in comparison of chemical and botanical characteristics of its commercial products. Dried leaves of P. viridis originating from Brazil, Peru and Hawaii were purchased from Internet providers. For DMT identification, thin layer chromatography (TLC) and high performance liquid chromatography (HPLC) methods have been elaborated, validated and applied. In order to clarify the existing differences among samples, chemometric methods have been used. Botanical features and the gas chromatography tandem mass spectrometry (GC-MS) chromatograms have been analyzed using hierarchical cluster analysis (HCA). Our studies revealed significant variety among plant material marketed as P. viridis. Grouping of samples based on their micromorphology features and GC-MS results did not correspond well with the presence of DMT. Based on our results an indisputable identification of dried specimens as P. viridis is very problematic. It is necessary to postulate changes in legislation regarding regulation of P. viridis and replace it with DMT as controlled substance.
[Mh] Termos MeSH primário: Psychotria/química
[Mh] Termos MeSH secundário: Cromatografia Líquida de Alta Pressão
Cromatografia em Camada Delgada
Análise por Conglomerados
Controle de Medicamentos e Entorpecentes
Cromatografia Gasosa-Espectrometria de Massas
Microscopia
Folhas de Planta
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Em] Mês de entrada:1601
[Cu] Atualização por classe:151209
[Lr] Data última revisão:
151209
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:151210
[St] Status:MEDLINE


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[PMID]:26552170
[Au] Autor:Fu YH; Huang LG; Wang XC; Li XB; Li KK; Wu SL; Liu YP
[Ti] Título:[Studies on chemical constituents from Psychotria straminea].
[So] Source:Zhongguo Zhong Yao Za Zhi;40(11):2138-43, 2015 Jun.
[Is] ISSN:1001-5302
[Cp] País de publicação:China
[La] Idioma:chi
[Ab] Resumo:The chemical consituents from Psychotria straminea were separated and purified by column chromatographies on silica gel, Sephadex LH-20, ODS and RP-HPLC. The strictures of the isolated compounds were identified on the basis of physicochemical properties and spectroscopic analysis, as well as comparisons with the data in literature. Sixteen compounds were isolated and elucidated as tectochrysin (1), apigenin (2), kaempferol (3), luteolin (4), diosmetin (5), quercetin (6), kaempferol-4'-O-methylether (7), rhamnetin (8), 7-hydroxycoumarin (9), 7-methoxycoumarin (10), scopoletin (11), lupeol (12), 30-oxo-lupeol (13), lupenyl acetate (14), α-amyrin (15), and ursolic acid (16). This is the first study on the chemical composition of P. Straminea, and all compounds were isolated from P. straminea for the first time. In addition to compounds 6 and 9, the other compounds were isolated from the genus Psychotria for the first time.
[Mh] Termos MeSH primário: Compostos Fitoquímicos/isolamento & purificação
Psychotria/química
[Mh] Termos MeSH secundário: Cumarínicos/química
Cumarínicos/isolamento & purificação
Flavonoides/química
Flavonoides/isolamento & purificação
Compostos Fitoquímicos/química
Triterpenos/química
Triterpenos/isolamento & purificação
[Pt] Tipo de publicação:ENGLISH ABSTRACT; JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Coumarins); 0 (Flavonoids); 0 (Phytochemicals); 0 (Triterpenes)
[Em] Mês de entrada:1512
[Cu] Atualização por classe:151110
[Lr] Data última revisão:
151110
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:151111
[St] Status:MEDLINE



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