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[PMID]:29367146
[Au] Autor:Vasantharaj S; Sripriya N; Shanmugavel M; Manikandan E; Gnanamani A; Senthilkumar P
[Ad] Endereço:Dept. of Biotechnology, Hindusthan College of Arts and Science, Coimbatore 641028, TN, India. Electronic address: svasanthraj06@gmail.com.
[Ti] Título:Surface active gold nanoparticles biosynthesis by new approach for bionanocatalytic activity.
[So] Source:J Photochem Photobiol B;179:119-125, 2018 Feb.
[Is] ISSN:1873-2682
[Cp] País de publicação:Switzerland
[La] Idioma:eng
[Ab] Resumo:In the present day, nanotechnology is one of the most promising leading scientific and potentials areas in modern key technology development toward to the humankind. The synthesis of noble metal nanoparticles (NPs) is an expanding research area due to the possible applications for the development of bio-medical applications. Eco-friendly approach for the biosynthesis of gold nanoparticles (AuNPs) using the aqueous extract from Ruellia tuberosa and Phyllanthus acidus (leaf and twig) for the first time. Surface active AuNPs were characterized by UV-Vis spectroscopy, FTIR (Fourier transform infrared) spectroscopy, DSC (differential scanning colorimetry), DLS (dynamic light scattering) and environmental SEM (scanning electron microscope) analysis at room temperature (RT). Enhanced surface plasmon resonance (SPR) absorbance UV visible optical spectra were detected in the range of 552, 548, 558 and 536 nm. SEM and DLS (transmission mode) analysis confirmed the morphology of the nanoparticles to be spherical with the average size in the range of 88.37, 94.31, 82.23 and 81.36 nm. Further they have enhanced the enzyme activity on α-amylase, cellulase, and xylanase. The results suggest that the phyto-fabricated AuNPs from R. tuberosa and P. acidus is simple, less expensive, eco-friendly, green synthesis and also can be exploited for the potential future industrial and bio-medical applications.
[Mh] Termos MeSH primário: Ouro/química
Nanopartículas Metálicas/química
[Mh] Termos MeSH secundário: Acanthaceae/química
Acanthaceae/metabolismo
Difusão Dinâmica da Luz
Química Verde
Microscopia Eletrônica de Varredura
Tamanho da Partícula
Phyllanthus/química
Phyllanthus/metabolismo
Extratos Vegetais/química
Folhas de Planta/química
Folhas de Planta/metabolismo
Espectrofotometria Ultravioleta
Espectroscopia de Infravermelho com Transformada de Fourier
Ressonância de Plasmônio de Superfície
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Plant Extracts); 7440-57-5 (Gold)
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180223
[Lr] Data última revisão:
180223
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180126
[St] Status:MEDLINE


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[PMID]:28859638
[Au] Autor:Suesatpanit T; Osathanunkul K; Madesis P; Osathanunkul M
[Ad] Endereço:Department of Biology, Faculty of Science, Chiang Mai University, Chiang Mai, 50200, Thailand.
[Ti] Título:Should DNA sequence be incorporated with other taxonomical data for routine identifying of plant species?
[So] Source:BMC Complement Altern Med;17(1):437, 2017 Aug 31.
[Is] ISSN:1472-6882
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: A variety of plants in Acanthaceae have long been used in traditional Thai ailment and commercialised with significant economic value. Nowadays medicinal plants are sold in processed forms and thus morphological authentication is almost impossible. Full identification requires comparison of the specimen with some authoritative sources, such as a full and accurate description and verification of the species deposited in herbarium. Intake of wrong herbals can cause adverse effects. Identification of both raw materials and end products is therefore needed. METHODS: Here, the potential of a DNA-based identification method, called Bar-HRM (DNA barcoding coupled with High Resolution Melting analysis), in raw material species identification is investigated. DNA barcode sequences from five regions (matK, rbcL, trnH-psbA spacer region, trnL and ITS2) of Acanthaceae species were retrieved for in silico analysis. Then the specific primer pairs were used in HRM assay to generate unique melting profiles for each plants species. RESULTS: The method allows identification of samples lacking necessary morphological parts. In silico analyses of all five selected regions suggested that ITS2 is the most suitable marker for Bar-HRM in this study. The HRM analysis on dried samples of 16 Acanthaceae medicinal species was then performed using primer pair derived from ITS2 region. 100% discrimination of the tested samples at both genus and species level was observed. However, two samples documented as Clinacanthus nutans and Clinacanthus siamensis were recognised as the same species from the HRM analysis. Further investigation reveals that C. siamensis is now accepted as C. nutans. CONCLUSIONS: The results here proved that Bar-HRM is a promising technique in species identification of the studied medicinal plants in Acanthaceae. In addition, molecular biological data is currently used in plant taxonomy and increasingly popular in recent years. Here, DNA barcode sequence data should be incorporated with morphological characters in the species identification.
[Mh] Termos MeSH primário: Acanthaceae/classificação
Código de Barras de DNA Taxonômico/métodos
DNA de Plantas/genética
Plantas Medicinais/classificação
[Mh] Termos MeSH secundário: Acanthaceae/genética
Plantas Medicinais/genética
Tailândia
[Pt] Tipo de publicação:EVALUATION STUDIES; JOURNAL ARTICLE
[Nm] Nome de substância:
0 (DNA, Plant)
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170908
[Lr] Data última revisão:
170908
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170902
[St] Status:MEDLINE
[do] DOI:10.1186/s12906-017-1937-3


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[PMID]:28534307
[Au] Autor:Shackira AM; Puthur JT; Nabeesa Salim E
[Ad] Endereço:Plant Physiology and Biochemistry Division, Department of Botany, University of Calicut, C.U. Campus P.O, Kerala, 673635, India.
[Ti] Título:Acanthus ilicifolius L. a promising candidate for phytostabilization of zinc.
[So] Source:Environ Monit Assess;189(6):282, 2017 Jun.
[Is] ISSN:1573-2959
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:The potential of a halophyte species-Acanthus ilicifolius L.-to phytostabilize zinc (Zn) grown under hydroponics culture conditions was critically evaluated in this study. The propagules after treating with ZnSO (4 mM) were analysed for the bioaccumulation pattern, translocation rate of Zn to the shoot, effects of Zn accumulation on organic solutes and the antioxidant defence system. It was found that most of the Zn absorbed by the plant was retained in the root (47%) and only a small portion was transported to stem (12%) and leaves (11%). This is further confirmed by the high BCF (bioconcentration factor) value (1.99) and low TF (translocation factor) value (0.5), which indicates the increased retention of Zn in the root itself. Moreover, treatment with Zn resulted in an increased accumulation of organic solutes (proline, free amino acids and soluble sugars) and non-enzymatic antioxidants (ascorbate, glutathione and phenol) in the leaf and root tissue. Likewise, the activity of antioxidant enzymes namely superoxide dismutase (SOD), catalase (CAT), guaiacol peroxidase (GPX) and ascorbate peroxidase (APX) recorded an enhanced activity upon exposure to Zn as compared to the control plants. Thus, the increased tolerance for Zn in A. ilicifolius may be attributed to the efficient free radical scavenging mechanisms operating under excess Zn. In addition, being a high accumulator (53.7 mg of Zn) and at the same time a poor translocator of Zn to the aerial parts of the plant, A. ilicifolius can be recommended as a potential candidate for the phytostabilization of Zn in the contaminated wetlands.
[Mh] Termos MeSH primário: Biodegradação Ambiental
Poluentes do Solo/metabolismo
Zinco/metabolismo
[Mh] Termos MeSH secundário: Acanthaceae
Antioxidantes/metabolismo
Ascorbato Peroxidases/metabolismo
Catalase/metabolismo
Monitoramento Ambiental
Glutationa/metabolismo
Hidroponia
Peroxidase
Folhas de Planta/química
Raízes de Plantas/química
Plantas Tolerantes a Sal
Poluentes do Solo/análise
Poluentes do Solo/toxicidade
Superóxido Dismutase/metabolismo
Zinco/análise
Zinco/toxicidade
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Antioxidants); 0 (Soil Pollutants); EC 1.11.1.- (guaiacol peroxidase); EC 1.11.1.11 (Ascorbate Peroxidases); EC 1.11.1.6 (Catalase); EC 1.11.1.7 (Peroxidase); EC 1.15.1.1 (Superoxide Dismutase); GAN16C9B8O (Glutathione); J41CSQ7QDS (Zinc)
[Em] Mês de entrada:1707
[Cu] Atualização por classe:171020
[Lr] Data última revisão:
171020
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170524
[St] Status:MEDLINE
[do] DOI:10.1007/s10661-017-6001-8


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[PMID]:28472046
[Au] Autor:Tripp EA; Tsai YE
[Ad] Endereço:Department of Ecology and Evolutionary Biology, University of Colorado, Boulder, Colorado, United States of America.
[Ti] Título:Disentangling geographical, biotic, and abiotic drivers of plant diversity in neotropical Ruellia (Acanthaceae).
[So] Source:PLoS One;12(5):e0176021, 2017.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:It has long been hypothesized that biotic interactions are important drivers of biodiversity evolution, yet such interactions have been relatively less studied than abiotic factors owing to the inherent complexity in and the number of types of such interactions. Amongst the most prominent of biotic interactions worldwide are those between plants and pollinators. In the Neotropics, the most biodiverse region on Earth, hummingbird and bee pollination have contributed substantially to plant fitness. Using comparative methods, we test the macroevolutionary consequences of bird and bee pollination within a species rich lineage of flowering plants: Ruellia. We additionally explore impacts of species occupancy of ever-wet rainforests vs. dry ecosystems including cerrado and seasonally dry tropical forests. We compared outcomes based on two different methods of model selection: a traditional approach that utilizes a series of transitive likelihood ratio tests as well as a weighted model averaging approach. Analyses yield evidence for increased net diversification rates among Neotropical Ruellia (compared to Paleotropical lineages) as well as among hummingbird-adapted species. In contrast, we recovered no evidence of higher diversification rates among either bee- or non-bee-adapted lineages and no evidence for higher rates among wet or dry habitat lineages. Understanding fully the factors that have contributed to biases in biodiversity across the planet will ultimately depend upon incorporating knowledge of biotic interactions as well as connecting microevolutionary processes to macroevolutionary patterns.
[Mh] Termos MeSH primário: Acanthaceae/classificação
Geografia
[Mh] Termos MeSH secundário: Filogenia
Polinização
Clima Tropical
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170907
[Lr] Data última revisão:
170907
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170505
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0176021


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[PMID]:28431014
[Au] Autor:Zhuang Y; Tripp EA
[Ad] Endereço:Department of Ecology and Evolutionary Biology, University of Colorado, UCB 334, Boulder, CO 80309, USA.
[Ti] Título:The draft genome of Ruellia speciosa (Beautiful Wild Petunia: Acanthaceae).
[So] Source:DNA Res;24(2):179-192, 2017 Apr 01.
[Is] ISSN:1756-1663
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:The genus Ruellia (Wild Petunias; Acanthaceae) is characterized by an enormous diversity of floral shapes and colours manifested among closely related species. Using Illumina platform, we reconstructed the draft genome of Ruellia speciosa, with a scaffold size of 1,021 Mb (or ∼1.02 Gb) and an N50 size of 17,908 bp, spanning ∼93% of the estimated genome (∼1.1 Gb). The draft assembly predicted 40,124 gene models and phylogenetic analyses of four key enzymes involved in anthocyanin colour production [flavanone 3-hydroxylase (F3H), flavonoid 3'-hydroxylase (F3'H), flavonoid 3',5'-hydroxylase (F3'5'H), and dihydroflavonol 4-reductase (DFR)] found that most angiosperms here sampled harboured at least one copy of F3H, F3'H, and DFR. In contrast, fewer than one-half (but including R. speciosa) harboured a copy of F3'5'H, supporting observations that blue flowers and/or fruits, which this enzyme is required for, are less common among flowering plants. Ka/Ks analyses of duplicated copies of F3'H and DFR in R. speciosa suggested purifying selection in the former but detected evidence of positive selection in the latter. The genome sequence and annotation of R. speciosa represents only one of only four families sequenced in the large and important Asterid clade of flowering plants and, as such, will facilitate extensive future research on this diverse group, particularly with respect to floral evolution.
[Mh] Termos MeSH primário: Acanthaceae/genética
Genoma de Planta
[Mh] Termos MeSH secundário: Acanthaceae/enzimologia
Oxirredutases do Álcool/genética
Antocianinas/biossíntese
Sistema Enzimático do Citocromo P-450/genética
Regulação da Expressão Gênica de Plantas
Genoma de Cloroplastos
Oxigenases de Função Mista/genética
Filogenia
Proteínas de Plantas/genética
Análise de Sequência de DNA
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Anthocyanins); 0 (Plant Proteins); 9035-51-2 (Cytochrome P-450 Enzyme System); EC 1.- (Mixed Function Oxygenases); EC 1.1.- (Alcohol Oxidoreductases); EC 1.1.1.- (dihydroflavanol 4-reductase); EC 1.14.- (flavonoid 3',5'-hydroxylase); EC 1.14.11.9 (flavanone 3-dioxygenase); EC 1.14.13.21 (flavonoid 3'-hydroxylase)
[Em] Mês de entrada:1707
[Cu] Atualização por classe:170726
[Lr] Data última revisão:
170726
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170422
[St] Status:MEDLINE
[do] DOI:10.1093/dnares/dsw054


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[PMID]:28359331
[Au] Autor:Alam MA; Zaidul IS; Ghafoor K; Sahena F; Hakim MA; Rafii MY; Abir HM; Bostanudin MF; Perumal V; Khatib A
[Ad] Endereço:Faculty of Pharmacy, International Islamic University Malaysia (IIUM), Kuantan Campus, 25200, Kuantan, Pahang, Malaysia.
[Ti] Título:In vitro antioxidant and, α-glucosidase inhibitory activities and comprehensive metabolite profiling of methanol extract and its fractions from Clinacanthus nutans.
[So] Source:BMC Complement Altern Med;17(1):181, 2017 Mar 31.
[Is] ISSN:1472-6882
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: This study was aimed to evaluate antioxidant and α-glucosidase inhibitory activity, with a subsequent analysis of total phenolic and total flavonoid content of methanol extract and its derived fractions from Clinacanthus nutans accompanied by comprehensive phytochemical profiling. METHODS: Liquid-liquid partition chromatography was used to separate methanolic extract to get hexane, ethyl acetate, butanol and residual aqueous fractions. The total antioxidant activity was determined by 2,2-diphenyl-1-picrylhydrazy (DPPH) radical scavenging and ferric reducing antioxidant power assay (FRAP). The antidiabetic activity of methanol extract and its consequent fractions were examined by α-glucosidase inhibitory bioassay. The chemical profiling was carried out by gas chromatography coupled with quadrupole time-of-flight mass spectrometry (GC Q-TOF MS). RESULTS: The total yield for methanol extraction was (12.63 ± 0.98) % (w/w) and highest fractionated value found for residual aqueous (52.25 ± 1.01) % (w/w) as compared to the other fractions. Significant DPPH free radical scavenging activity was found for methanolic extract (63.07 ± 0.11) % and (79.98 ± 0.31) % for ethyl acetate fraction among all the fractions evaluated. Methanol extract was the most prominent in case of FRAP (141.89 ± 0.87 µg AAE/g) whereas most effective reducing power observed in ethyl acetate fraction (133.6 ± 0.2987 µg AAE/g). The results also indicated a substantial α-glucosidase inhibitory activity for butanol fraction (72.16 ± 1.0) % and ethyl acetate fraction (70.76 ± 0.49) %. The statistical analysis revealed that total phenolic and total flavonoid content of the samples had the significant (p < 0.05) impact on DPPH free radical scavenging and α-glucosidase inhibitory activity. CONCLUSION: Current results proposed the therapeutic potential of Clinacanthus nutans, especially ethyl acetate and butanol fraction as chemotherapeutic agent against oxidative related cellular damages and control the postprandial hyperglycemia. The phytochemical investigation showed the existence of active constituents in Clinacanthus nutans extract and fractions.
[Mh] Termos MeSH primário: Acanthaceae/química
Antioxidantes/química
Inibidores de Glicosídeo Hidrolases/química
Extratos Vegetais/química
[Mh] Termos MeSH secundário: Antioxidantes/isolamento & purificação
Antioxidantes/metabolismo
Inibidores de Glicosídeo Hidrolases/isolamento & purificação
Inibidores de Glicosídeo Hidrolases/metabolismo
Extratos Vegetais/isolamento & purificação
Extratos Vegetais/metabolismo
Caules de Planta/química
alfa-Glucosidases/química
alfa-Glucosidases/metabolismo
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Antioxidants); 0 (Glycoside Hydrolase Inhibitors); 0 (Plant Extracts); EC 3.2.1.20 (alpha-Glucosidases)
[Em] Mês de entrada:1704
[Cu] Atualização por classe:170417
[Lr] Data última revisão:
170417
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170401
[St] Status:MEDLINE
[do] DOI:10.1186/s12906-017-1684-5


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[PMID]:28253196
[Au] Autor:Quah SY; Chin JH; Akowuah GA; Khalivulla SI; Yeong SW; Sabu MC
[Ti] Título:Cytotoxicity and cytochrome P450 inhibitory activities of Clinacanthus nutans.
[So] Source:Drug Metab Pers Ther;32(1):59-65, 2017 Mar 01.
[Is] ISSN:2363-8915
[Cp] País de publicação:Germany
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Clinacanthus nutans Lindau (family: Acanthaceae), also known as "Sabah Snake Grass" or "Belalai Gajah" in Malaysia, has been widely used by Malaysians due to its anticancer property. However, the anticancer activity of C. nutans leaves extract and its safe use need to be further investigated. The objectives of the present study were to evaluate the cytotoxic effects of methanol leaves extract of C. nutans in various human cancer cell lines and to evaluate the in vitro effect of C. nutans leaves on the activity of CYP3A4 and CYP2E1 in human liver microsomes. METHODS: The cytotoxic effects of methanol extract of C. nutans leaves in various cancer cell lines (Hep-G2, A549, HT-29, MDA-MB-231, MCF-7, and CRL 1739) and normal cells (3T3) were determined using 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) cell proliferation assay. The activities of CYP3A4 and CYP2E1 were determined using simple spectrophotometric methods. RESULTS: Results obtained showed that the methanol extract of C. nutans leaves exhibited the highest cytotoxic effect against Hep-G2 cell lines (liver cancer) (IC50=13.33 µg/mL), followed by breast cancer oestrogen negative (MDA-MB-231) (IC50 of 18.67 µg/mL). Methanol leaves extract of C. nutans showed significant inhibition (p<0.05) in CYP3A4 and CYP2E1 activity in human liver microsomes. CONCLUSIONS: In conclusion, methanol leaves extract of C. nutans exhibited the highest cytotoxic activity against liver cancer cells (Hep-G2). There is a possibility that herb-drug interaction could occur with C. nutans through inhibitory effects on CYP3A4. Additionally, inhibition of C. nutans on CYP2E1 could show anti-carcinogenesis effects in human liver microsomes.
[Mh] Termos MeSH primário: Acanthaceae/química
Antineoplásicos Fitogênicos/farmacologia
Inibidores das Enzimas do Citocromo P-450/farmacologia
Sistema Enzimático do Citocromo P-450/metabolismo
[Mh] Termos MeSH secundário: Células 3T3
Animais
Antineoplásicos Fitogênicos/química
Antineoplásicos Fitogênicos/isolamento & purificação
Linhagem Celular Tumoral
Proliferação Celular/efeitos dos fármacos
Inibidores das Enzimas do Citocromo P-450/química
Inibidores das Enzimas do Citocromo P-450/isolamento & purificação
Relação Dose-Resposta a Droga
Ensaios de Seleção de Medicamentos Antitumorais
Medicina Tradicional
Camundongos
Relação Estrutura-Atividade
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Antineoplastic Agents, Phytogenic); 0 (Cytochrome P-450 Enzyme Inhibitors); 9035-51-2 (Cytochrome P-450 Enzyme System)
[Em] Mês de entrada:1711
[Cu] Atualização por classe:171108
[Lr] Data última revisão:
171108
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170303
[St] Status:MEDLINE


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[PMID]:28198202
[Au] Autor:Zulkipli IN; Rajabalaya R; Idris A; Sulaiman NA; David SR
[Ad] Endereço:a Pengiran Anak Puteri Rashidah Sa'adatul Bolkiah Institute of Health Sciences, Universiti Brunei Darussalam, Jalan Tungku Link , Gadong , Brunei Darussalam.
[Ti] Título:Clinacanthus nutans: a review on ethnomedicinal uses, chemical constituents and pharmacological properties.
[So] Source:Pharm Biol;55(1):1093-1113, 2017 Dec.
[Is] ISSN:1744-5116
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:CONTEXT: Medicinal plants have attracted global attention for their hidden therapeutic potential. Clinacanthus nutans (Burm.f) Lindau (Acanthaceae) (CN) is endemic in Southeast Asia. CN contains phytochemicals common to medicinal plants, such as flavonoids. Traditionally, CN has been used for a broad range of human ailments including snake bites and cancer. OBJECTIVES: This article compiles the ethnomedicinal uses of CN and its phytochemistry, and thus provides a phytochemical library of CN. It also discusses the known pharmacological and biological effects of CN to enable better investigation of CN. METHODS: This literature review was limited to articles and websites published in the English language. MEDLINE and Google Scholar databases were searched from December 2014 to September 2016 using the following keywords: "Clinacanthus nutans" and "Belalai gajah". The results were reviewed to identify relevant articles. Information from relevant selected studies was systematically analyzed from contemporary ethnopharmacological sources, evaluated against scientific literature, and extracted into tables. RESULTS: The literature search yielded 124 articles which were then further scrutinized revealing the promising biological activities of CN, including antimicrobial, antiproliferative, antitumorigenic and anti-inflammatory effects. Few articles discussed the mechanisms for these pharmacological activities. Furthermore, CN was beneficial in small-scale clinical trials for genital Herpes and aphthous stomatitis. CONCLUSION: Despite the rich ethnomedicinal knowledge behind the traditional uses of CN, the current scientific evidence to support these claims remains scant. More research is still needed to validate these medicinal claims, beginning by increasing the understanding of the biological actions of this plant.
[Mh] Termos MeSH primário: Acanthaceae
Medicina Tradicional
Extratos Vegetais/farmacologia
[Mh] Termos MeSH secundário: Acanthaceae/anatomia & histologia
Acanthaceae/química
Anti-Infecciosos/farmacologia
Anti-Inflamatórios/farmacologia
Antineoplásicos Fitogênicos/farmacologia
Antioxidantes/farmacologia
Ásia Sudeste
Seres Humanos
Compostos Fitoquímicos/análise
Fitoterapia
Extratos Vegetais/toxicidade
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Nm] Nome de substância:
0 (Anti-Infective Agents); 0 (Anti-Inflammatory Agents); 0 (Antineoplastic Agents, Phytogenic); 0 (Antioxidants); 0 (Phytochemicals); 0 (Plant Extracts)
[Em] Mês de entrada:1703
[Cu] Atualização por classe:170303
[Lr] Data última revisão:
170303
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170216
[St] Status:MEDLINE
[do] DOI:10.1080/13880209.2017.1288749


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[PMID]:28183831
[Au] Autor:Abdala-Roberts L; Parra-Tabla V; Moreira X; Ramos-Zapata J
[Ad] Endereço:Departamento de Ecología Tropical, Campus de Ciencias Biológicas y Agropecuarias, Universidad Autónoma de Yucatán, Apartado Postal 4-116, Itzimná 97000 Mérida, Yucatán, Mexico abdala.luis@yahoo.com.
[Ti] Título:Ecological and evolutionary consequences of tri-trophic interactions: Spatial variation and effects of plant density.
[So] Source:Am J Bot;104(2):241-251, 2017 Feb.
[Is] ISSN:1537-2197
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:PREMISE OF STUDY: The factors driving variation in species interactions are often unknown, and few studies have made a link between changes in interactions and the strength of selection. METHODS: We report on spatial variation in functional responses by a seed predator (SP) and its parasitic wasps associated with the herb . We assessed the influence of plant density on consumer responses and determined whether density effects and spatial variation in functional responses altered natural selection by these consumers on the plant. We established common gardens at two sites in Yucatan, Mexico, and planted at two densities in each garden. We recorded fruit output and SP and parasitoid attack; calculated relative fitness (seed number) under scenarios of three trophic levels (accounting for SP and parasitoid effects), two trophic levels (accounting for SP but not parasitoid effects), and one trophic level (no consumer effects); and compared selection strength on fruit number under these scenarios across sites and densities. KEY RESULTS: There was spatial variation in SP recruitment, whereby the SP functional response was negatively density-dependent at one site but density-independent at the other; parasitoid responses were density-independent and invariant across sites. Site variation in SP attack led, in turn, to differences in SP selection on fruit output, and parasitoids did not alter SP selection. There were no significant effects of density at either site. CONCLUSIONS: Our results provide a link between consumer functional responses and consumer selection on plants, which deepens our understanding of geographic variation in the evolutionary outcomes of multitrophic interactions.
[Mh] Termos MeSH primário: Acanthaceae/parasitologia
Ecologia
Ecossistema
Vespas/fisiologia
[Mh] Termos MeSH secundário: Acanthaceae/fisiologia
Animais
Evolução Biológica
Frutas/parasitologia
Frutas/fisiologia
Interações Hospedeiro-Parasita
México
Densidade Demográfica
Sementes/parasitologia
Sementes/fisiologia
Seleção Genética
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170815
[Lr] Data última revisão:
170815
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170211
[St] Status:MEDLINE
[do] DOI:10.3732/ajb.1600358


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[PMID]:28158188
[Au] Autor:Bargues MD; Gayo V; Sanchis J; Artigas P; Khoubbane M; Birriel S; Mas-Coma S
[Ad] Endereço:Departamento de Parasitología, Facultad de Farmacia, Universidad de Valencia, Valencia, Spain.
[Ti] Título:DNA multigene characterization of Fasciola hepatica and Lymnaea neotropica and its fascioliasis transmission capacity in Uruguay, with historical correlation, human report review and infection risk analysis.
[So] Source:PLoS Negl Trop Dis;11(2):e0005352, 2017 Feb.
[Is] ISSN:1935-2735
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Fascioliasis is a pathogenic disease transmitted by lymnaeid snails and recently emerging in humans, in part due to effects of climate changes, anthropogenic environment modifications, import/export and movements of livestock. South America is the continent presenting more human fascioliasis hyperendemic areas and the highest prevalences and intensities known. These scenarios appear mainly linked to altitude areas in Andean countries, whereas lowland areas of non-Andean countries, such as Uruguay, only show sporadic human cases or outbreaks. A study including DNA marker sequencing of fasciolids and lymnaeids, an experimental study of the life cycle in Uruguay, and a review of human fascioliasis in Uruguay, are performed. METHODOLOGY/PRINCIPAL FINDINGS: The characterization of Fasciola hepatica from cattle and horses of Uruguay included the complete sequences of the ribosomal DNA ITS-2 and ITS-1 and mitochondrial DNA cox1 and nad1. ITS-2, ITS-1, partial cox1 and rDNA 16S gene of mtDNA were used for lymnaeids. Results indicated that vectors belong to Lymnaea neotropica instead of to Lymnaea viator, as always reported from Uruguay. The life cycle and transmission features of F. hepatica by L. neotropica of Uruguay were studied under standardized experimental conditions to enable a comparison with the transmission capacity of F. hepatica by Galba truncatula at very high altitude in Bolivia. On this baseline, we reviewed the 95 human fascioliasis cases reported in Uruguay and analyzed the risk of human infection in front of future climate change estimations. CONCLUSIONS/SIGNIFICANCE: The correlation of fasciolid and lymnaeid haplotypes with historical data on the introduction and spread of livestock into Uruguay allowed to understand the molecular diversity detected. Although Uruguayan L. neotropica is a highly efficient vector, its transmission capacity is markedly lower than that of Bolivian G. truncatula. This allows to understand the transmission and epidemiological differences between Andean highlands and non-Andean lowlands in South America. Despite rainfall increase predictions for Uruguay, nothing suggests a trend towards a worrying human infection scenario as in Andean areas.
[Mh] Termos MeSH primário: Acanthaceae/parasitologia
Fasciola hepatica/classificação
Fasciola hepatica/isolamento & purificação
Fasciolíase/transmissão
Variação Genética
[Mh] Termos MeSH secundário: Animais
Bovinos
Análise por Conglomerados
DNA de Helmintos/química
DNA de Helmintos/genética
DNA Ribossômico/química
DNA Ribossômico/genética
DNA Espaçador Ribossômico/química
DNA Espaçador Ribossômico/genética
Fasciola hepatica/genética
Fasciolíase/epidemiologia
Genótipo
Cavalos
Seres Humanos
Filogenia
RNA Ribossômico 16S/genética
Medição de Risco
Análise de Sequência de DNA
Uruguai
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (DNA, Helminth); 0 (DNA, Ribosomal); 0 (DNA, Ribosomal Spacer); 0 (RNA, Ribosomal, 16S)
[Em] Mês de entrada:1706
[Cu] Atualização por classe:170619
[Lr] Data última revisão:
170619
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170204
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pntd.0005352



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