Base de dados : MEDLINE
Pesquisa : B01.650.940.800.575.912.250.583.520.075 [Categoria DeCS]
Referências encontradas : 24 [refinar]
Mostrando: 1 .. 10   no formato [Detalhado]

página 1 de 3 ir para página          

  1 / 24 MEDLINE  
              next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:27189840
[Au] Autor:Rigano D; Marrelli M; Formisano C; Menichini F; Senatore F; Bruno M; Conforti F
[Ad] Endereço:a Department of Pharmacy , University of Naples "Federico II" , Naples , Italy.
[Ti] Título:Phytochemical profile of three Ballota species essential oils and evaluation of the effects on human cancer cells.
[So] Source:Nat Prod Res;31(4):436-444, 2017 Feb.
[Is] ISSN:1478-6427
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Three Ballota species, Ballota undulata, Ballota saxatilis and Ballota nigra ssp. foetida, were investigated for their cytotoxicity against two human cancer cells, hepatoma HepG2 cell line and breast cancer MCF-7 cell line, and for their antioxidant activity. The chemical composition of essential oils was studied by GC and GC-MS. Sesquiterpenes were the main constituents. The most antiproliferative essential oil against HepG2 cells was B. undulata with a percentage of inhibition of 81.36 ± 3.54 at a concentration of 100 µg/mL, while against MCF-7 cells essential oil from B. saxatilis was the most active with a percentage of inhibition of 24.18 ± 1.13 at a concentration of 100 µg/mL. The antioxidant activity was investigated by DPPH test for all the oils. B. undulata showed the highest antiradical effect, with IC value of 529.7 ± 37.4 µg/mL.
[Mh] Termos MeSH primário: Antineoplásicos Fitogênicos/farmacologia
Ballota/química
Óleos Voláteis/análise
[Mh] Termos MeSH secundário: Antioxidantes/farmacologia
Cromatografia Gasosa-Espectrometria de Massas
Células Hep G2
Seres Humanos
Células MCF-7
Óleos Voláteis/farmacologia
Sesquiterpenos/análise
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Antineoplastic Agents, Phytogenic); 0 (Antioxidants); 0 (Oils, Volatile); 0 (Sesquiterpenes)
[Em] Mês de entrada:1705
[Cu] Atualização por classe:170817
[Lr] Data última revisão:
170817
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160519
[St] Status:MEDLINE
[do] DOI:10.1080/14786419.2016.1185722


  2 / 24 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:27144646
[Au] Autor:Dordevic AS; Jovanovic OP; Zlatkovic BK; Stojanovic GS
[Ad] Endereço:Department of Chemistry, Faculty of Science and Mathematics, University of Nis, Visegradska 33, 18000, Nis, Serbia.
[Ti] Título:Chemical Composition of Ballota macedonica Vandas and Ballota nigra L. ssp. foetida (Vis.) Hayek Essential Oils - The Chemotaxonomic Approach.
[So] Source:Chem Biodivers;13(6):782-8, 2016 Jun.
[Is] ISSN:1612-1880
[Cp] País de publicação:Switzerland
[La] Idioma:eng
[Ab] Resumo:The essential oils isolated from fresh aerial parts of Ballota macedonica (two populations) and Ballota nigra ssp. foetida were analyzed by GC and GC/MS. Eighty five components were identified in total; 60 components in B. macedonica oil (population from the Former Yugoslav Republic of Macedonia), 34 components in B. macedonica oil (population from the Republic of Serbia), and 33 components in the oil of B. nigra ssp. foetida accounting for 93.9%, 98.4%, and 95.8% of the total oils, respectively. The most abundant components in B. macedonica oils were carotol (13.7 - 52.1%), germacrene D (8.6 - 24.6%), and (E)-caryophyllene (6.5 - 16.5%), while B. nigra ssp. foetida oil was dominated by (E)-phytol (56.9%), germacrene D (10.0%), and (E)-caryophyllene (4.7%). Multivariate statistical analyses (agglomerative hierarchical cluster analysis and principal component analysis) were used to compare and discuss relationships among Ballota species examined so far based on their volatile profiles. The chemical compositions of B. macedonica essential oils are reported for the first time.
[Mh] Termos MeSH primário: Ballota/química
Óleos Voláteis/isolamento & purificação
[Mh] Termos MeSH secundário: Cromatografia Gasosa
Análise por Conglomerados
Espectrometria de Massas
Óleos Voláteis/química
Análise de Componente Principal
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Oils, Volatile)
[Em] Mês de entrada:1701
[Cu] Atualização por classe:170113
[Lr] Data última revisão:
170113
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160505
[St] Status:MEDLINE
[do] DOI:10.1002/cbdv.201500254


  3 / 24 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
[PMID]:26647634
[Au] Autor:Makowczynska J; Grzegorczyk-KAROLAK I; Wysokinska H
[Ti] Título:ANTIOXIDANT ACTIVITY OF TISSUE CULTURE-RAISED BALLOTA NIGRA L. PLANTS GROWN EX VITRO.
[So] Source:Acta Pol Pharm;72(4):769-75, 2015 Jul-Aug.
[Is] ISSN:0001-6837
[Cp] País de publicação:Poland
[La] Idioma:eng
[Ab] Resumo:Antioxidant properties and total phenolic and flavonoid contents were evaluated in methanolic extracts of shoots from Ballota nigra plants initiated in vitro (from nodal explants) and in vivo (from seeds). The plants were grown in greenhouse and in the field, and were analyzed at the vegetative and flowering stages. The shoot extract of wild-grown plants of B. nigra was also investigated. The results indicate that antioxidant potential of the B. nigra extracts seems to be due to their scavenging of free radicals (DPPH assay) and metal reducing (FRAP test), while they were less effective at the prevention of linoleic acid peroxidation (LPO test). The extracts from shoots of in vitro derived plants were found to exhibit the greatest antioxidant properties. The extracts were also characterized by the highest content of phenolic compounds and their level was affected by plant developmental stage. The extracts of shoots collected at the flowering period exhibited higher amounts of phenolics and flavonoids than in the extracts of immature plants. A close correlation between the total phenolic content and flavonoid content and antioxidant activity using the DPPH and FRAP assays was obtained. The results of the present study suggest the use in vitro-derived plants of B. nigra instead of using wild plants for pharmaceutical purposes.
[Mh] Termos MeSH primário: Antioxidantes/farmacologia
Ballota
Extratos Vegetais/farmacologia
[Mh] Termos MeSH secundário: Ballota/química
Flavonoides/análise
Fenóis/análise
Técnicas de Cultura de Tecidos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Antioxidants); 0 (Flavonoids); 0 (Phenols); 0 (Plant Extracts)
[Em] Mês de entrada:1601
[Cu] Atualização por classe:151209
[Lr] Data última revisão:
151209
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:151210
[St] Status:MEDLINE


  4 / 24 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
[PMID]:25230517
[Au] Autor:Fraternale D; Ricci D
[Ti] Título:Essential oil composition and antifungal activity of aerial parts of Ballota nigra ssp foetida collected at flowering and fruiting times.
[So] Source:Nat Prod Commun;9(7):1015-8, 2014 Jul.
[Is] ISSN:1934-578X
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:The present study reports the results of gas chromatographic-mass spectrometric (GC/MS) analyses of the essential oils from the aerial parts of Ballota nigra L. ssp foetida (Lamiaceae) collected at flowering and fruiting times, as well as their in vitro antifungal activity against nine plant pathogenic fungi. Moreover, the essential oils were evaluated for their antifungal activity using the agar dilution method, and also MICs (minimum inhibitory concentrations) and MFCs (minimum fungicidal concentrations) were determined. The major compounds identified in the flowering and fruiting aerial parts oils respectively were beta-caryophyllene (22.6% and 21.8%), caryophyllene oxide (18.0% and 20.5%) and germacrene-D (16.5 and 13.1%). The oils showed in vitro antifungal activity against some species of Fusarium, Botrytis cinerea, and Alternaria solani. Our study indicates that the oil of B. nigra ssp foetida could be used as a control agent for plant pathogenic fungi in natural formulations.
[Mh] Termos MeSH primário: Ballota/química
Flores/fisiologia
Frutas/fisiologia
Componentes Aéreos da Planta/química
Óleos Vegetais/química
Óleos Vegetais/farmacologia
[Mh] Termos MeSH secundário: Antifúngicos/química
Antifúngicos/farmacologia
Fusarium/efeitos dos fármacos
Óleos Voláteis/química
Óleos Voláteis/farmacologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Antifungal Agents); 0 (Oils, Volatile); 0 (Plant Oils)
[Em] Mês de entrada:1410
[Cu] Atualização por classe:140918
[Lr] Data última revisão:
140918
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:140919
[St] Status:MEDLINE


  5 / 24 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
PubMed Central Texto completo
Texto completo
[PMID]:25054139
[Au] Autor:Ullah N; Ahmad I; Ayaz S
[Ad] Endereço:Department of Chemistry, Kohat University of Science & Technology, Kohat, Khyber Pakhtunkhwa 26000, Pakistan.
[Ti] Título:In vitro antimicrobial and antiprotozoal activities, phytochemical screening and heavy metals toxicity of different parts of Ballota nigra.
[So] Source:Biomed Res Int;2014:321803, 2014.
[Is] ISSN:2314-6141
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:The study was done to assess the phytochemicals (flavonoids, terpenoids, saponins, tannin, alkaloids, and phenol) in different parts (root, stem, and leaves) of Ballota nigra and correlated it to inhibition of microbes (bacteria and fungi), protozoan (Leishmania), and heavy metals toxicity evaluation. In root and stem flavonoids, terpenes and phenols were present in ethanol, chloroform, and ethyl acetate soluble fraction; these were found to be the most active inhibiting fractions against all the tested strains of bacteria, fungi, and leishmania. While in leaves flavonoids, terpenes, and phenols were present in ethanol, chloroform, and n-butanol fractions which were the most active fractions against both types of microbes and protozoan (leishmania) in in vitro study. Ethanol and chloroform fractions show maximum inhibition against Escherichia coli (17 mm). The phytochemical and biological screenings were correlated with the presence of heavy metals in selected plant Ballota nigra. Cr was found above permissible value (above 1.5 mg/kg) in all parts of the plant. Ni was above WHO limit in B. nigra root and leaves (3.35 ± 1.20 mg/kg and 5.09 ± 0.47 mg/kg, respectively). Fe was above permissible value in all parts of B. nigra (above 20 mg/kg). Cd was above permissible value in all parts of the plant (above 0.3 mg/kg). Pb was above WHO limit (above 2 mg/kg) in all parts of Ballota nigra.
[Mh] Termos MeSH primário: Anti-Infecciosos/química
Antiprotozoários/química
Ballota/química
Metais Pesados/química
[Mh] Termos MeSH secundário: Antibacterianos/química
Antifúngicos/química
Testes de Sensibilidade Microbiana
Compostos Fitoquímicos/química
Extratos Vegetais/química
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Anti-Bacterial Agents); 0 (Anti-Infective Agents); 0 (Antifungal Agents); 0 (Antiprotozoal Agents); 0 (Metals, Heavy); 0 (Phytochemicals); 0 (Plant Extracts)
[Em] Mês de entrada:1510
[Cu] Atualização por classe:140723
[Lr] Data última revisão:
140723
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:140724
[St] Status:MEDLINE
[do] DOI:10.1155/2014/321803


  6 / 24 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
[PMID]:22474939
[Au] Autor:Farooq U; Khan A; Khan AF; Khan SS; Sarwar R; Ahmad VU; Waseem A
[Ad] Endereço:Department of Chemistry, COMSATS Institute of Information Technology, Abbottabad-22060, Pakistan. umarf@ciit.net.pk
[Ti] Título:Two new ballonigrin-type diterpenoids from the roots of Ballota limbata.
[So] Source:Nat Prod Commun;7(2):149-50, 2012 Feb.
[Is] ISSN:1934-578X
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Two new ballonigrin type lactone diterpenoids, named ballonigrin lactone A and B, have been isolated from the roots of Ballota limbata. Structure elucidation of the isolated compounds was based on spectroscopic {IR, 1H- and 3C-NMR, and 2D-NMR (HMQC, HMBC, COSY and NOESY} and EI-MS data.
[Mh] Termos MeSH primário: Ballota/química
Diterpenos/química
Lactonas/química
Raízes de Plantas/química
[Mh] Termos MeSH secundário: Estrutura Molecular
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Diterpenes); 0 (Lactones); 0 (ballonigrin lactone A); 0 (ballonigrin lactone B)
[Em] Mês de entrada:1204
[Cu] Atualização por classe:120405
[Lr] Data última revisão:
120405
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:120406
[St] Status:MEDLINE


  7 / 24 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:21554006
[Au] Autor:Haq Ru; Farooq U; Wahab A; Raza M; Ahmad VU; Khan RA
[Ad] Endereço:Institute of Neurophysiology, Charité-Universitätsmedizin Berlin, Berlin, Germany. rizwan-ul.haq@charite.de
[Ti] Título:Investigation of antitussive and toxicological activity of Ballota limbata in mice.
[So] Source:Pharm Biol;49(6):627-32, 2011 Jun.
[Is] ISSN:1744-5116
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:CONTEXT: Ballota limbata Benth. (Lamiaceae) (syn, Otostegia limbata Hook.f.) is a species grown in the North West Frontier Province and the lower hills of West Punjab, Pakistan. Ballota species are renowned for their antispasmodic, antiulcer, diuretic, vermifuge, and especially sedative effects. However, little is known about the biological activity of B. limbata. OBJECTIVE: Evaluation of antitussive activity and safety profile of dried B. limbata extract. MATERIALS AND METHODS: Whole air-dried plants were partitioned with various solvents and the butanol fraction was subjected to antitussive evaluation using a sulfur dioxide (SO(2))-induced cough model in mice. Codeine and dextromethorphan were used as positive control. Safety profile of the testing material was established using standard toxicity tests. RESULTS: B. limbata extract inhibited cough provoked by SO(2) gas in mice in a dose-dependent manner. The extract exhibited maximum protection against SO(2)-induced cough after 60 min of administration. B. limbata offered maximum cough suppressive effects, that is, number of coughs during 60 min was 11.66 ± 1.2 (mean ± SEM), after s.c. administration of 800 mg/kg, as compared with codeine 10 mg/kg, s.c., dextromethorphan 10 mg/kg, s.c., and saline showing a frequency of cough of 11.75 ± 1.18, 12.25 ± 0.83, and 46.25 ± 1.52, respectively. LD(50) value of B. limbata was greater than 5000 mg/kg. No sign of neural impairment was observed at antitussive doses and the extract has been well-tolerated at higher doses. DISCUSSION AND CONCLUSION: This study demonstrates that the extract of B. limbata has shown strong cough suppressive effect in mice without yielding any notable toxicity.
[Mh] Termos MeSH primário: Antitussígenos/toxicidade
Antitussígenos/uso terapêutico
Tosse/tratamento farmacológico
Fitoterapia/métodos
Extratos Vegetais/toxicidade
Extratos Vegetais/uso terapêutico
[Mh] Termos MeSH secundário: Animais
Ballota/química
Codeína/uso terapêutico
Tosse/induzido quimicamente
Dextrometorfano/uso terapêutico
Modelos Animais de Doenças
Relação Dose-Resposta a Droga
Avaliação Pré-Clínica de Medicamentos
Feminino
Dose Letal Mediana
Masculino
Medicina Tradicional
Camundongos
Camundongos Endogâmicos
Paquistão
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Antitussive Agents); 0 (Plant Extracts); 7355X3ROTS (Dextromethorphan); Q830PW7520 (Codeine)
[Em] Mês de entrada:1108
[Cu] Atualização por classe:140730
[Lr] Data última revisão:
140730
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:110511
[St] Status:MEDLINE
[do] DOI:10.3109/13880209.2011.563317


  8 / 24 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:21091260
[Au] Autor:Erdogan-Orhan I; Sever-Yilmaz B; Altun ML; Saltan G
[Ad] Endereço:Department of Pharmacognosy, Faculty of Pharmacy, Gazi University, Ankara, Turkey. iorhan@gazi.edu.tr
[Ti] Título:Radical quenching activity, ferric-reducing antioxidant power, and ferrous ion-chelating capacity of 16 Ballota species and their total phenol and flavonoid contents.
[So] Source:J Med Food;13(6):1537-43, 2010 Dec.
[Is] ISSN:1557-7600
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:The ethyl acetate, methanol, and water extracts of 16 Ballota species (Family Lamiaceae)-Ballota acetabulosa, Ballota antalyanse, Ballota cristata, Ballota glandulosissima, Ballota inaequidens, Ballota larendana, Ballota latibracteolata, Ballota macrodonta, Ballota nigra ssp. anatolica, B. nigra ssp. foetida, B. nigra ssp. nigra, B. nigra ssp. uncinata, Ballota pseudodictamnus ssp. lycia, Ballota rotundifolia, Ballota saxatilis ssp. brachyodonta, and B. saxatilis subsp. saxatilis-were screened for their 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical quenching, ferric-reducing antioxidant power, and ferrous ion-chelating capacity at 1mg/mL. Hispanolone, a major diterpene found in the Ballota genus, was also tested in the same manner. Total phenol and flavonoid contents of the extracts were determined by Folin-Ciocalteau and AlCl(3) reagents, respectively. The extracts showed insignificant quenching activity against DPPH radical, but they had moderate antioxidant activity (0.597 ± 0.03 to 1.342 ± 0.01) in the ferric-reducing test compared to chlorogenic acid (the reference compound) (3.618 ± 0.01). All of the extracts (ranging from 65.1 ± 0.64% to 96.3 ± 0.09%) and hispanolone (97.31 ± 0.30%) exerted a remarkable ferrous ion-chelating effect. The highest total phenol (gallic acid equivalent) and flavonoid (quercetin equivalent) contents were found in the ethyl acetate extract of B. glandulosissima (393.7 ± 3.03 and 140.6 ± 1.97 mg/g of extract, respectively). Therefore, Ballota species could be a good source of natural preservatives in foodstuffs.
[Mh] Termos MeSH primário: Antioxidantes/farmacologia
Ballota/química
Flavonoides/análise
Quelantes de Ferro/farmacologia
Fenóis/análise
Extratos Vegetais/química
Extratos Vegetais/farmacologia
[Mh] Termos MeSH secundário: Algoritmos
Antioxidantes/química
Diterpenos/farmacologia
Descoberta de Drogas
Flavonoides/farmacologia
Conservantes de Alimentos/isolamento & purificação
Conservantes de Alimentos/farmacologia
Depuradores de Radicais Livres/química
Depuradores de Radicais Livres/farmacologia
Quelantes de Ferro/química
Concentração Osmolar
Oxirredução
Estresse Oxidativo/efeitos dos fármacos
Fenóis/farmacologia
Componentes Aéreos da Planta/química
Extratos Vegetais/isolamento & purificação
Solventes
Turquia
[Pt] Tipo de publicação:COMPARATIVE STUDY; JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Antioxidants); 0 (Diterpenes); 0 (Flavonoids); 0 (Food Preservatives); 0 (Free Radical Scavengers); 0 (Iron Chelating Agents); 0 (Phenols); 0 (Plant Extracts); 0 (Solvents); 0 (hispanolone)
[Em] Mês de entrada:1103
[Cu] Atualização por classe:101124
[Lr] Data última revisão:
101124
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:101125
[St] Status:MEDLINE
[do] DOI:10.1089/jmf.2009.0237


  9 / 24 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
[PMID]:19476011
[Au] Autor:Fraternale D; Bucchini A; Giamperi L; Ricci D
[Ad] Endereço:Istituto di Botanica e Orto Botanico "P. Scaramella", Facoltà di Farmacia, Università degli Studi di Urbino "Carlo Bo", Urbino (PU), Italy.
[Ti] Título:Essential oil composition and antimicrobial activity of Ballota nigra L. ssp foetida.
[So] Source:Nat Prod Commun;4(4):585-8, 2009 Apr.
[Is] ISSN:1934-578X
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:The chemical composition of the essential oil of Ballota nigra L. ssp foetida obtained from the flowering aerial parts was analyzed by GC/MS. From the 37 identified constituents of the oil, beta-caryophyllene (20.0%), germacrene D (18.0%) and caryophyllene oxide (15.0%) were the major components. The oil was active against both Gram-negative and Gram-positive bacteria as well as against three Candida species.
[Mh] Termos MeSH primário: Anti-Infecciosos/farmacologia
Ballota/química
Óleos Voláteis/farmacologia
[Mh] Termos MeSH secundário: Anti-Infecciosos/química
Anti-Infecciosos/isolamento & purificação
Bactérias/efeitos dos fármacos
Candida/efeitos dos fármacos
Cromatografia Gasosa-Espectrometria de Massas
Testes de Sensibilidade Microbiana
Óleos Voláteis/química
Óleos Voláteis/isolamento & purificação
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Anti-Infective Agents); 0 (Oils, Volatile)
[Em] Mês de entrada:0907
[Cu] Atualização por classe:090529
[Lr] Data última revisão:
090529
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:090530
[St] Status:MEDLINE


  10 / 24 MEDLINE  
              first record previous record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:19459749
[Au] Autor:Vukovic N; Sukdolak S; Solujic S; Niciforovic N
[Ad] Endereço:Department of Chemistry, Faculty of Science, University of Kragujevac, Kragujevac, Serbia. nvukovic@kg.ac.yu
[Ti] Título:Antimicrobial activity of the essential oil obtained from roots and chemical composition of the volatile constituents from the roots, stems, and leaves of Ballota nigra from Serbia.
[So] Source:J Med Food;12(2):435-41, 2009 Apr.
[Is] ISSN:1557-7600
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:The chemical composition of essential oils obtained from the roots, stems, and leaves of Ballota nigra, growing in Serbia, was investigated by gas chromatography/mass spectrometry analyses. Kovats indices, mass spectra, and standard compounds were used to identify a total of 115 individual compounds. The plant produces two types of essential oils. Oils derived from stems and leaves were sesquiterpene rich (78.17% and 88.40%, respectively), containing principally beta-caryophyllene, germacrene D, and alpha-humulene, present in appreciable amounts. In contrast, oil derived from the root was dominated by p-vinylguiacol (9.24%), borneol (7.51%), myrtenol (7.13%), trans-pinocarveol (5.22%), pinocarvone (4.37%), 2-methyl-3-phenylpropanal (4.32%), and p-cymen-8-ol (4.30%). Essential oil obtained from the roots was evaluated for the antimicrobial activity against seven bacterial species and one fungi.
[Mh] Termos MeSH primário: Antibacterianos/farmacologia
Antifúngicos/farmacologia
Ballota/química
Óleos Voláteis/farmacologia
Óleos Vegetais/farmacologia
[Mh] Termos MeSH secundário: Antibacterianos/química
Antibacterianos/isolamento & purificação
Antifúngicos/química
Antifúngicos/isolamento & purificação
Óleos Voláteis/química
Óleos Voláteis/isolamento & purificação
Folhas de Planta
Óleos Vegetais/química
Raízes de Plantas
Caules de Planta
Sérvia
Sesquiterpenos/isolamento & purificação
Sesquiterpenos/farmacologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Anti-Bacterial Agents); 0 (Antifungal Agents); 0 (Oils, Volatile); 0 (Plant Oils); 0 (Sesquiterpenes)
[Em] Mês de entrada:0909
[Cu] Atualização por classe:090522
[Lr] Data última revisão:
090522
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:090523
[St] Status:MEDLINE
[do] DOI:10.1089/jmf.2008.0164



página 1 de 3 ir para página          
   


Refinar a pesquisa
  Base de dados : MEDLINE Formulário avançado   

    Pesquisar no campo  
1  
2
3
 
           



Search engine: iAH v2.6 powered by WWWISIS

BIREME/OPAS/OMS - Centro Latino-Americano e do Caribe de Informação em Ciências da Saúde