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[PMID]:28503740
[Au] Autor:Karkanis A; Lykas C; Liava V; Bezou A; Petropoulos S; Tsiropoulos N
[Ad] Endereço:Department of Agriculture Crop Production and Rural Environment, University of Thessaly, Volos, Greece.
[Ti] Título:Weed interference with peppermint (Mentha x piperita L.) and spearmint (Mentha spicata L.) crops under different herbicide treatments: effects on biomass and essential oil yield.
[So] Source:J Sci Food Agric;98(1):43-50, 2018 Jan.
[Is] ISSN:1097-0010
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: 'Minor crops' such as spearmint and peppermint are high added value crops, despite the fact that their production area is comparably small worldwide. The main limiting factor in mint commercial cultivation is weed competition. Thus, field experiments were carried out to evaluate the effects of weed interference on growth, biomass and essential oil yield in peppermint and spearmint under different herbicide treatments. RESULTS: The application of pendimethalin and oxyfluorfen provided better control of annual weeds resulting in higher crop yield. Additionally, when treated with herbicides both crops were more competitive against annual weeds in the second year than in the first year. All pre-emergence herbicides increased biomass yield, since pendimethalin, linuron and oxyfluorfen reduced the density of annual weeds by 71-92%, 63-74% and 86-95%, respectively. Weed interference and herbicide application had no effect on essential oil content; however, a relatively strong impact on essential oil production per cultivated area unit was observed, mainly due to the adverse effect of weed interference on plant growth. CONCLUSION: Considering that pendimethalin and oxyfluorfen were effective against annual weeds in both spearmint and peppermint crops, these herbicides should be included in integrated weed management systems for better weed management in mint crops. © 2017 Society of Chemical Industry.
[Mh] Termos MeSH primário: Herbicidas/farmacologia
Mentha piperita/crescimento & desenvolvimento
Mentha spicata/crescimento & desenvolvimento
Óleos Voláteis/análise
Extratos Vegetais/análise
Plantas Daninhas/efeitos dos fármacos
[Mh] Termos MeSH secundário: Compostos de Anilina/farmacologia
Cruzamento
Éteres Difenil Halogenados/farmacologia
Mentha piperita/química
Mentha piperita/efeitos dos fármacos
Mentha piperita/genética
Mentha spicata/química
Mentha spicata/efeitos dos fármacos
Mentha spicata/genética
Plantas Daninhas/crescimento & desenvolvimento
Controle de Plantas Daninhas
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Aniline Compounds); 0 (Halogenated Diphenyl Ethers); 0 (Herbicides); 0 (Oils, Volatile); 0 (Plant Extracts); 46GY4Y6567 (oxyfluorofen); VL6L14C06U (pendimethalin)
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180102
[Lr] Data última revisão:
180102
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170516
[St] Status:MEDLINE
[do] DOI:10.1002/jsfa.8435


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[PMID]:28576378
[Au] Autor:de Oliveira KÁR; Berger LRR; de Araújo SA; Câmara MPS; de Souza EL
[Ad] Endereço:Laboratory of Food Microbiology, Department of Nutrition, Federal University of Paraíba, João Pessoa, Brazil.
[Ti] Título:Synergistic mixtures of chitosan and Mentha piperita L. essential oil to inhibit Colletotrichum species and anthracnose development in mango cultivar Tommy Atkins.
[So] Source:Food Microbiol;66:96-103, 2017 Sep.
[Is] ISSN:1095-9998
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:This study assessed the efficacy of chitosan (CHI) and Mentha piperita L. essential oil (MPEO) alone or in combination to control the mycelial growth of five different Colletotrichum species, C. asianum, C. dianesei, C. fructicola, C. tropicale and C. karstii, identified as potential anthracnose-causing agents in mango (Mangifera indica L.). The efficacy of coatings of CHI and MPEO mixtures in controlling the development of anthracnose in mango cultivar Tommy Atkins was evaluated. CHI (2.5, 5, 7.5 and 10 mg/mL) and MPEO (0.3, 0.6, 1.25, 2.5 and 5 µL/mL) alone effectively inhibited mycelial growth of all tested Colletotrichum strains in synthetic media. Mixtures of CHI (5 or 7.5 mg/mL) and MPEO (0.3, 0.6 or 1.25 µL/mL) strongly inhibited mycelial growth and showed additive or synergistic inhibitory effects on the tested Colletotrichum strains based on the Abbott index. The application of coatings of CHI (5 or 7.5 mg/mL) and MPEO (0.6 or 1.25 µL/mL) mixtures that presented synergistic interactions decreased anthracnose lesion severity in mango artificially contaminated with either of the tested Colletotrichum strains over 15 days of storage at 25 °C. The anthracnose lesion severity in mango coated with the mixtures of CHI and MPEO was similar or lower than those observed in mango treated with the synthetic fungicides thiophanate-methyl (10 µg a.i./mL) and difenoconazole (0.5 µg a.i./mL). The application of coatings containing low doses of CHI and MPEO may be an effective alternative for controlling the postharvest development of anthracnose in mango cultivar Tommy Atkins.
[Mh] Termos MeSH primário: Quitosana/farmacologia
Colletotrichum/efeitos dos fármacos
Fungicidas Industriais/farmacologia
Mangifera/microbiologia
Doenças das Plantas/microbiologia
Óleos Vegetais/farmacologia
[Mh] Termos MeSH secundário: Antracose
Colletotrichum/crescimento & desenvolvimento
Frutas/crescimento & desenvolvimento
Frutas/microbiologia
Mangifera/crescimento & desenvolvimento
Mentha piperita/química
Doenças das Plantas/prevenção & controle
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Fungicides, Industrial); 0 (Plant Oils); 9012-76-4 (Chitosan); AV092KU4JH (peppermint oil)
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170824
[Lr] Data última revisão:
170824
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170604
[St] Status:MEDLINE


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[PMID]:28334238
[Au] Autor:Ebadollahi A; Davari M; Razmjou J; Naseri B
[Ad] Endereço:Moghan College of Agriculture and Natural Resources, University of Mohaghegh Ardabili, Ardabil, Iran ( ebadollahi@uma.ac.ir ).
[Ti] Título:Separate and Combined Effects of Mentha piperata and Mentha pulegium Essential Oils and a Pathogenic Fungus Lecanicillium muscarium Against Aphis gossypii (Hemiptera: Aphididae).
[So] Source:J Econ Entomol;110(3):1025-1030, 2017 Jun 01.
[Is] ISSN:1938-291X
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:In the present study, the toxicity of essential oils of Mentha piperata L. and Mentha pulegium L. and pathogenicity of Lecanicillium muscarium (Zare & Gams) were studied in the melon aphid, Aphis gossypii Glover. Analyses of the essential oils by GC-MS indicated limonene (27.28%), menthol (24.71%), menthone (14.01%), and carvol (8.46%) in the M. piperata essential oil and pulegone (73.44%), piperitenone (5.49%), decane (4.99%), and limonene (3.07%) in the essential oil of M. pulegium as the main components. Both essential oils and the pathogenic fungus had useful toxicity against A. gossypii. Probit analysis indicated LC50 values (lethal concentrations to kill 50% of population; 95% confidence limits in parentheses) of M. piperata and M. pulegium essential oils as 15.25 (12.25-19.56) and 23.13 (19.27-28.42) µl/liter air, respectively. Susceptibility to the pathogenic fungus increased with exposure time. Aphid mortality also increased when the essential oils were combined with L. muscarium, although the phenomena was additive rather than synergistic. Mycelial growth inhibition of L. muscarium exposed to the essential oils was also very low. Based on our results, M. piperata and M. pulegium essential oils and the pathogenic fungus L. muscarium have some potential for management of A. gossypii.
[Mh] Termos MeSH primário: Afídeos/efeitos dos fármacos
Afídeos/microbiologia
Hypocreales/fisiologia
Inseticidas/farmacologia
Óleos Voláteis/farmacologia
[Mh] Termos MeSH secundário: Animais
Mentha piperita/química
Mentha pulegium/química
Controle Biológico de Vetores
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Insecticides); 0 (Oils, Volatile)
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170915
[Lr] Data última revisão:
170915
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170324
[St] Status:MEDLINE
[do] DOI:10.1093/jee/tox065


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[PMID]:28013374
[Au] Autor:Lalthazuali; Mathew N
[Ad] Endereço:Vector Control Research Centre (ICMR), Indira Nagar, Pondicherry, 605006, India.
[Ti] Título:Mosquito repellent activity of volatile oils from selected aromatic plants.
[So] Source:Parasitol Res;116(2):821-825, 2017 Feb.
[Is] ISSN:1432-1955
[Cp] País de publicação:Germany
[La] Idioma:eng
[Ab] Resumo:Essential oils from fresh leaves of four aromatic plants viz., Ocimum sanctum, Mentha piperita, Eucalyptus globulus and Plectranthus amboinicus were extracted by hydrodistillation. The test solutions were prepared as 20% essential oil in ethanol and positive control as 20% DEET in ethanol. Essential oil blend was prepared as 5% concentration. Nulliparous, 3-5-day-old female adult Aedes aegypti mosquitoes were used for repellency screening as per ICMR protocol. The study showed that the repellency of 20% essential oil of O. sanctum, M. piperita and P. amboinicus were comparable with that of the standard DEET (20%) as no mosquito landing on the test was observed up to 6 h. The E. globulus oil exhibited mosquito repellency only upto 1½ h. Considerable mosquito landing and feeding was displayed in negative control. In the case of the oil blend, no landing of mosquitoes was seen up to 6 h as that of positive control. The results showed that the essential oil blend from O. sanctum, M. piperita, E. globulus and P. amboinicus could repel Ae. aegypti mosquitoes or prevent from feeding as in the case of DEET even at a lower concentration of 5%. This study demonstrates the potential of essential oils from O. sanctum, M. piperita, E. globulus and P. amboinicus and their blend as mosquito repellents against Ae. aegypti, the vector of dengue, chikungunya and yellow fever.
[Mh] Termos MeSH primário: Aedes/efeitos dos fármacos
Dengue/prevenção & controle
Repelentes de Insetos/farmacologia
Controle de Mosquitos/métodos
Óleos Voláteis/farmacologia
Óleos Vegetais/farmacologia
[Mh] Termos MeSH secundário: Animais
Dengue/virologia
Eucalyptus/química
Feminino
Mentha piperita/química
Ocimum sanctum/química
Folhas de Planta/química
Plectranthus/química
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Insect Repellents); 0 (Oils, Volatile); 0 (Plant Oils)
[Em] Mês de entrada:1706
[Cu] Atualização por classe:171007
[Lr] Data última revisão:
171007
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161226
[St] Status:MEDLINE
[do] DOI:10.1007/s00436-016-5351-4


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[PMID]:28011360
[Au] Autor:Begas E; Tsioutsiouliti A; Kouvaras E; Haroutounian SA; Kasiotis KM; Kouretas D; Asprodini E
[Ad] Endereço:Laboratory of Pharmacology, School of Medicine, University of Thessaly, Larissa, Greece.
[Ti] Título:Effects of peppermint tea consumption on the activities of CYP1A2, CYP2A6, Xanthine Oxidase, N-acetyltranferase-2 and UDP-glucuronosyltransferases-1A1/1A6 in healthy volunteers.
[So] Source:Food Chem Toxicol;100:80-89, 2017 Feb.
[Is] ISSN:1873-6351
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Peppermint leaves are widely used for the symptomatic treatment of digestive disorders. Previous studies have shown significant effects of its natural products on human enzyme activity; however, there is no study available concerning the effects of peppermint tea on metabolizing enzymes in humans. Aim of the present study was to investigate the effect of peppermint tea on CYP1A2, CYP2A6, Xanthine Oxidase (XO), N-acetyltranferase-2 (NAT2) and UDP-glucuronosyltransferases-1A1/1A6 (UGT1A1/1A6) activities in healthy subjects. Four males and five females consumed peppermint tea (2 g of dry leaves/200 mL water, twice daily) for six days. CYP1A2, CYP2A6, XO, NAT2 and UGT1A1/1A6 activities were determined before and at the end of the study period, using the following caffeine and paracetamol metabolic ratios: CYP1A2: 17MX/137MX (saliva) and (AFMU+1MU+1MX)/17MU (urine); CYP2A6: 17MU/(17MU + 17MX), XO: 1MU/(1MU+1MX), NAT2, AFMU/(AFMU+1MU+1MX) and UGT1A1/1A6 glucuronidated/total paracetamol, all determined in urine. NAT2 metabolic ratio was significantly reduced following peppermint consumption (0.15 ± 0.13 vs 0.14 ± 0.13; p < 0.05). CYP1A2 urine and saliva indices were reduced, yet not significantly, following peppermint consumption (urine: 3.17 ± 1.08 vs 2.91 ± 0.76, saliva: 0.56 ± 0.12 vs 0.50 ± 0.12; p > 0.05). Peppermint had no influence on CYP2A6, XO and UGT1A1/1A6 indices. Daily ingestion of peppermint tea may alter pharmacokinetics of clinically administered drugs and promote cancer chemoprevention through NAT2 inhibition.
[Mh] Termos MeSH primário: Arilamina N-Acetiltransferase/metabolismo
Citocromo P-450 CYP1A2/metabolismo
Citocromo P-450 CYP2A6/metabolismo
Regulação Enzimológica da Expressão Gênica/efeitos dos fármacos
Glucuronosiltransferase/metabolismo
Mentha piperita/química
Extratos Vegetais/farmacologia
Chá/química
Xantina Oxidase/metabolismo
[Mh] Termos MeSH secundário: Adulto
Cromatografia Líquida
Feminino
Voluntários Saudáveis
Seres Humanos
Masculino
Espectrometria de Massas
Meia-Idade
Extratos Vegetais/química
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Plant Extracts); 0 (Tea); EC 1.14.14.1 (CYP1A2 protein, human); EC 1.14.14.1 (CYP2A6 protein, human); EC 1.14.14.1 (Cytochrome P-450 CYP1A2); EC 1.14.14.1 (Cytochrome P-450 CYP2A6); EC 1.17.3.2 (Xanthine Oxidase); EC 2.3.1.5 (Arylamine N-Acetyltransferase); EC 2.3.1.5 (NAT2 protein, human); EC 2.4.1.17 (Glucuronosyltransferase)
[Em] Mês de entrada:1704
[Cu] Atualização por classe:170404
[Lr] Data última revisão:
170404
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161225
[St] Status:MEDLINE


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[PMID]:28124962
[Au] Autor:Ergüden C; Özkoç S; Öztürk B; Bayram Delibas S
[Ad] Endereço:Dokuz Eylul University Faculty of Medicine, Department of Parasitology, Izmir, Turkey. cerenerguden@hotmail.com.
[Ti] Título:[Investigation of the in vitro effects of Melissa officinalis L., Mentha x piperita L. and Ocimum basilicum L. (Lamiaceae) essential oils on the cysts and trophozoites of Acanthamoeba castellani].
[Ti] Título:Melissa officinalis L., Mentha x piperita L. ve Ocimum basilicum L. (Lamiaceae) uçucu yaglarinin Acanthamoeba castellani kist ve trofozoitleri üzerine in vitro etkisinin arastirilmasi..
[So] Source:Mikrobiyol Bul;50(4):569-579, 2016 Oct.
[Is] ISSN:0374-9096
[Cp] País de publicação:Turkey
[La] Idioma:tur
[Ab] Resumo:Acanthamoeba species are free living amoeba found widely all over the world. They are responsible for Acanthamoeba keratitis (AK), an infection which is especially seen in contact lens users and after minor corneal traumas, that may lead blindness. At present, antifungals and antiseptics are used for the treatment of AK cases, however, some problems such as long treatment periods and the occurrence of side effects, resistance of cyst forms against drugs, emphasize the need for new drugs. There are some published studies that pointed out the effectiveness of plant extracts and essential oils on Acanthamoeba spp. The aim of this study was to investigate the in vitro effects of essential oils of Mentha x piperita L. (peppermint), Melissa officinalis L. (lemon balm) and Ocimum basilicum L. (basil) belonging to Lamiaceae family, on the cysts and trophozoites of Acanthamoeba castellanii. The strain used in our study, namely A. castellanii T4 genotype, is the most frequently isolated amoeba from environment and also the causative agent of AK and granulomatous amebic encephalitis. For the determination of amebicidal activity, essential oils obtained from Mentha x priperita L., Melissa officinalis L. and Ocimum basilicum L. by Neo-Clevenger type of distillation apparatus have been used. In vitro experiments were performed by using 96-well microplates. Cyst and trophozoite solutions were added on the essential oil dilutions to obtain the last concentrations of 40, 20, 10, 5, 2.5 and 1.25 µg/ml for the cysts, and 10, 5, 2.5, 1.25, 0.625 and 0.313 µg/ml for the trophozoites. After the incubation of microplates at 30oC for 1, 6, 24, 48 and 72 hours, the viability of parasitic forms were evaluated under the light microscope followed by staining trypan blue. It was found that, each essential oil showed amebicidal effect on A.castellani cysts and trophozoites dependent on dosage and time, when compared with the control group, The maximum lethal effect occured with Melissa officinalis followed by Mentha x piperita and Ocimum basilicum, respectively. In our study, susceptibility of A.castellanii trophozoites to essential oils were more than the cysts, as expected. The essential oils of Melissa officinalis and Mentha x piperita showed 100% lethal effect at their highest concentrations whereas the essential oil of Ocimum basilicum showed only 63.3% lethal effect on cysts after 72 hours at the highest concentration (40 µg/mL). The results of this first study investigating the activities of essential oils extracted from Mentha x piperita, Melissa officinalis and Ocimum basilicum against Acanthamoeba spp. cysts and trophozoites, have suggested that, these essential oils could be potential novel and alternative natural products for the treatment of Acanthamoeba spp. infections.
[Mh] Termos MeSH primário: Acanthamoeba castellanii/efeitos dos fármacos
Melissa/química
Mentha piperita/química
Ocimum basilicum/química
Óleos Voláteis/farmacologia
[Mh] Termos MeSH secundário: Ceratite por Acanthamoeba/tratamento farmacológico
Ceratite por Acanthamoeba/parasitologia
Amebíase/tratamento farmacológico
Amebíase/parasitologia
Seres Humanos
Óleos Vegetais/farmacologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Oils, Volatile); 0 (Plant Oils)
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170831
[Lr] Data última revisão:
170831
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170127
[St] Status:MEDLINE


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[PMID]:27912953
[Au] Autor:Tavakoli Ardakani M; Ghassemi S; Mehdizadeh M; Mojab F; Salamzadeh J; Ghassemi S; Hajifathali A
[Ad] Endereço:Department of Clinical Pharmacy, School of Pharmacy, Shahid Beheshti University of Medical Sciences, Tehran, Iran; Pharmaceutical sciences research center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
[Ti] Título:Evaluating the effect of Matricaria recutita and Mentha piperita herbal mouthwash on management of oral mucositis in patients undergoing hematopoietic stem cell transplantation: A randomized, double blind, placebo controlled clinical trial.
[So] Source:Complement Ther Med;29:29-34, 2016 Dec.
[Is] ISSN:1873-6963
[Cp] País de publicação:Scotland
[La] Idioma:eng
[Ab] Resumo:OBJECTIVES: To investigate the effects of Matricaria recutita and Mentha piperita on oral mucositis (OM) in patients undergoing hematopoietic stem cell transplantation (HSCT). DESIGN: Randomized double blind placebo controlled clinical trial. SETTING: Faculty of Pharmacy, Shahid Beheshti University of Medical Sciences, and Bone Marrow Transplantation Center at Taleghani Teaching Hospital, Tehran, Iran. PARTICIPANTS: Sixty patients undergoing HSCT were randomly assigned to two groups: placebo (n=33), and herbal mouthwash group (n=27). INTERVENTIONS: All patients received the mouthwash one week before HSCT and were instructed to use it three times daily for at least 30s. MAIN OUTCOME MEASURES: OM was graded using National Cancer Institute Common Toxicity Criteria (NCI-CTC) scale (grade 0-5). The Numerical Rating Scale (NRS: 0-10 scale) measured the severity of OM symptoms. RESULTS: The duration, maximum and average daily grade of OM were significantly reduced in the treatment group (P<0.05). The use of herbal mouthwash led to significant improvements in pain intensity (P=0.009), dryness (P=0.04) and dysphagia (P=0.009). Other significant results included: reduced need for complementary medications (P=0.03), narcotic analgesics (P=0.047), total parenteral nutrition (TPN) (P=0.02) and the duration of TPN (P=0.03). CONCLUSION: This study shows that patients receiving the herbal mouthwash experienced less complications and symptoms associated with OM. In summary, it seems that the use of our prepared herbal mouthwash is beneficial for patients undergoing HSCT.
[Mh] Termos MeSH primário: Medicamentos de Ervas Chinesas/uso terapêutico
Transplante de Células-Tronco Hematopoéticas/efeitos adversos
Matricaria/química
Mentha piperita/química
Antissépticos Bucais/uso terapêutico
Estomatite/tratamento farmacológico
[Mh] Termos MeSH secundário: Adulto
Método Duplo-Cego
Feminino
Seres Humanos
Masculino
[Pt] Tipo de publicação:CLINICAL TRIAL; JOURNAL ARTICLE; RANDOMIZED CONTROLLED TRIAL
[Nm] Nome de substância:
0 (Drugs, Chinese Herbal); 0 (Mouthwashes)
[Em] Mês de entrada:1704
[Cu] Atualização por classe:170404
[Lr] Data última revisão:
170404
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161204
[St] Status:MEDLINE


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[PMID]:27515877
[Au] Autor:Mutluay Yayla E; Izgu N; Ozdemir L; Aslan Erdem S; Kartal M
[Ad] Endereço:Nursing Faculty, Hacettepe University, 06000 Sihhiye, Ankara, Turkey. Electronic address: ezgmtly@gmail.com.
[Ti] Título:Sage tea-thyme-peppermint hydrosol oral rinse reduces chemotherapy-induced oral mucositis: A randomized controlled pilot study.
[So] Source:Complement Ther Med;27:58-64, 2016 Aug.
[Is] ISSN:1873-6963
[Cp] País de publicação:Scotland
[La] Idioma:eng
[Ab] Resumo:OBJECTIVE: This pilot study aimed to investigate the preventive effect of sage tea-thyme-peppermint hydrosol oral rinse used in conjunction with basic oral care on chemotherapy-induced oral mucositis. DESIGN: An open-label randomized controlled study. SETTING: Two oncology hospitals in Ankara, Turkey. INTERVENTIONS: Patients receiving 5-fluorouracil-based chemotherapy regimens were divided into the intervention group (N=30) and control group (N=30). Basic oral care was prescribed to the control group, while the intervention group was prescribed sage tea-thyme-peppermint hydrosol in addition to basic oral care. All patients were called to assess their compliance with the study instructions on day 5 and 14. MAIN OUTCOME MEASURES: Oral mucositis was evaluated using an inspection method or by assessing oral cavity photos based on the World Health Organization oral toxicity scale on day 5 and 14. RESULTS: Most of the patients in the intervention group did not develop oral mucositis on day 5. In addition, the incidence of grade 1 oral mucositis was statistically lower in the intervention group (10%) than the control group (53.3%) on day 5. By day 14, the majority of patients in both the groups had grade 0 oral mucositis. CONCLUSIONS: Sage tea-thyme-peppermint hydrosol oral rinse has promising results in alleviating oral mucositis. This hydrosol can be recommended for clinical use as it is well tolerated and cost-effective. However, further randomized controlled trials are needed to support the study.
[Mh] Termos MeSH primário: Antissépticos Bucais/administração & dosagem
Preparações de Plantas/administração & dosagem
Estomatite/induzido quimicamente
Estomatite/tratamento farmacológico
[Mh] Termos MeSH secundário: Feminino
Seres Humanos
Masculino
Mentha piperita/química
Meia-Idade
Plantas Medicinais
Salvia officinalis/química
Chá/química
Thymus (Planta)/química
Turquia
[Pt] Tipo de publicação:JOURNAL ARTICLE; RANDOMIZED CONTROLLED TRIAL
[Nm] Nome de substância:
0 (Mouthwashes); 0 (Plant Preparations); 0 (Tea)
[Em] Mês de entrada:1703
[Cu] Atualização por classe:170331
[Lr] Data última revisão:
170331
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160813
[St] Status:MEDLINE


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[PMID]:27417677
[Au] Autor:Valente JS; Fonseca AO; Denardi LB; Dal Ben VS; Maia Filho FS; Zambrano CG; Braga CQ; Alves SH; Botton SA; Brayer Pereira DI
[Ad] Endereço:Universidade Federal de Pelotas (UFPel), Pelotas, RS, Brazil.
[Ti] Título:In vitro activity of antifungals in combination with essential oils against the oomycete Pythium insidiosum.
[So] Source:J Appl Microbiol;121(4):998-1003, 2016 Oct.
[Is] ISSN:1365-2672
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:AIMS: The aim of this study was to investigate the in vitro susceptibility of Pythium insidiosum to combinations of the antifungal drugs terbinafine or itraconazole with Melaleuca alternifolia, Mentha piperita and Origanum vulgare essential oils (EOs). METHODS AND RESULTS: In vitro combinations of antifungal drugs with EOs were evaluated by checkerboard microdilution method against 20 Brazilian isolates of P. insidiosum. The tests were performed according to protocol M38-A2, and the interpretation of each combination result was based on the values of the fractional inhibitory concentration index. The combinations of itraconazole with EOs presented prominent synergistic effects against P. insidiosum isolates, and no antagonism was observed with these combinations. However, the combinations of terbinafine with EOs resulted in indifferent or antagonistic effects. CONCLUSIONS: The combination of plant-derived bioactive compounds with antifungal drugs may be an alternative therapy for the control of infections caused by P. insidiosum. Studies of new therapeutic protocols involving these proposed combinations are needed. SIGNIFICANCE AND IMPACT OF THE STUDY: The antimicrobial combinations using EOs with terbinafine or itraconazole can be an attractive therapeutic option for controlling P. insidiosum infections.
[Mh] Termos MeSH primário: Antifúngicos/farmacologia
Mentha piperita/química
Naftalenos/farmacologia
Óleos Voláteis/farmacologia
Origanum/química
Pythium/efeitos dos fármacos
[Mh] Termos MeSH secundário: Animais
Anti-Infecciosos/farmacologia
Brasil
Quimioterapia Combinada
Doenças dos Cavalos/tratamento farmacológico
Cavalos
Testes de Sensibilidade Microbiana
Pitiose/tratamento farmacológico
Pitiose/parasitologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Anti-Infective Agents); 0 (Antifungal Agents); 0 (Naphthalenes); 0 (Oils, Volatile); G7RIW8S0XP (terbinafine)
[Em] Mês de entrada:1703
[Cu] Atualização por classe:170817
[Lr] Data última revisão:
170817
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160716
[St] Status:MEDLINE
[do] DOI:10.1111/jam.13234


  10 / 271 MEDLINE  
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[PMID]:27396216
[Au] Autor:Buleandra M; Oprea E; Popa DE; David IG; Moldovan Z; Mihai I; Badea IA
[Ti] Título:Comparative Chemical Analysis of Mentha piperita and M. spicata and a Fast Assessment of Commercial Peppermint Teas.
[So] Source:Nat Prod Commun;11(4):551-5, 2016 Apr.
[Is] ISSN:1934-578X
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:The hydrodistilled essential oils and volatile compounds (by static headspaces technique) of Mentha piperita L. and M spicata L. were characterized by GC-MS. Headspace analysis of Mentha piperita revealed the existence of menthone (25.4%), 1,8-cineole (17.7%) and menthol (12.1%) as the main components, while the essential oil contained high amounts of menthol (46.8%) and menthone (25.6%). By contrast, headspace analysis of M. spicata showed a high content of limonene (37.0%) together with carvone (13.0%), ß-pinene (10.4%) and α-pinene (9.8%), while the essential oil was reach in carvone (51.7%), dihydrocarveol (11.5%) and cis-dihydrocarvone (9.1%). Eleven samples of peppermint tea available on the Romanian market were analysed by headspace GC-MS. The volatile profile of the tea samples was compared with that of Mentha piperita L. and certain differences were emphasized and discussed.
[Mh] Termos MeSH primário: Mentha piperita/química
Mentha spicata/química
Óleos Voláteis/química
Chá/química
Compostos Orgânicos Voláteis/química
[Pt] Tipo de publicação:COMPARATIVE STUDY; JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Oils, Volatile); 0 (Tea); 0 (Volatile Organic Compounds)
[Em] Mês de entrada:1609
[Cu] Atualização por classe:160711
[Lr] Data última revisão:
160711
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160712
[St] Status:MEDLINE



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