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Pesquisa : B01.650.940.800.575.912.250.583.640.416 [Categoria DeCS]
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  1 / 96 MEDLINE  
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[PMID]:29214362
[Au] Autor:Zhuo T; Zhu LJ; Lu CC; Jiang CY; Chen ZY; Zhang G; Wang ZH; Jovel J; Han YH
[Ad] Endereço:College of Plant Protection, Fujian Agriculture and Forestry University, Fuzhou, 350002, China.
[Ti] Título:Complete nucleotide sequence of jasmine virus H, a new member of the family Tombusviridae.
[So] Source:Arch Virol;163(3):731-735, 2018 Mar.
[Is] ISSN:1432-8798
[Cp] País de publicação:Austria
[La] Idioma:eng
[Ab] Resumo:Jasmine virus H (JaVH) is a novel virus associated with symptoms of yellow mosaic on jasmine. The JaVH genome is 3,867 nt in length with five open reading frames (ORFs) encoding a 27-kDa protein (ORF 1), an 87-kDa replicase protein (ORF 2), two centrally located movement proteins (ORF 3 and 4), and a 37-kDa capsid protein (ORF 5). Based on genomic and phylogenetic analysis, JaVH is predicted to be a member of the genus Pelarspovirus in the family Tombusviridae.
[Mh] Termos MeSH primário: Genoma Viral
Jasminum/virologia
Filogenia
RNA Viral/genética
Tombusviridae/genética
[Mh] Termos MeSH secundário: Sequência de Bases
Proteínas do Capsídeo/genética
Sequenciamento de Nucleotídeos em Larga Escala
Fases de Leitura Aberta
RNA Replicase/genética
Tombusviridae/classificação
Tombusviridae/isolamento & purificação
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Capsid Proteins); 0 (RNA, Viral); EC 2.7.7.48 (RNA Replicase)
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180220
[Lr] Data última revisão:
180220
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171208
[St] Status:MEDLINE
[do] DOI:10.1007/s00705-017-3663-z


  2 / 96 MEDLINE  
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[PMID]:28419158
[Au] Autor:Deng Y; Sun X; Gu C; Jia X; Liang L; Su J
[Ad] Endereço:Provincial Key Laboratory for Horticultural Crop Genetic Improvement, Institute of Leisure Agriculture, Jiangsu Academy of Agricultural Sciences, Nanjing, Jiangsu, China.
[Ti] Título:Identification of pre-fertilization reproductive barriers and the underlying cytological mechanism in crosses among three petal-types of Jasminum sambac and their relevance to phylogenetic relationships.
[So] Source:PLoS One;12(4):e0176026, 2017.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Crosses among single-, double- and multi-petal jasmine cultivars (Jasminum sambac Aiton) are unable to easily generate hybrids. To identify the reproductive barriers restricting hybrid set, dynamic changes in jasmine pollen viability and pistil receptivity were compared at different flowering stages. Pollen-pistil interactions in six reciprocal crosses were also investigated to characterize pollen-stigma compatibility. Additionally, paraffin sections of pollinated embryo sacs were prepared for subsequent analyses of developmental status. Furthermore, pistil cell ultrastructural characteristics were observed to reveal cytological mechanism regulating pistil receptivity and the pollen-pistil interactions. We observed that pollen viability and stigma receptivity varied depending on petal phenotype and flowering stage and were easily lost during flowering. Different reciprocal crosses exhibited varied pollen-stigma compatibilities according to the pollen germination rates. Although some pollen grains germinated normally on maternal stigmas, the pollen tubes were arrested in the pistils and were unable to reach the ovaries. Additionally, the embryo sacs remained unfertilized until degenerating. Therefore, jasmine crosses are affected by pre-fertilization reproductive barriers. Low pollen fertility and poor stigma receptivity are detrimental to pollen germination and pollen-pistil compatibility, indicating they are two factors affecting hybrid set. Ultrastructural observation of the pistil cells revealed that cell death occurred during flowering. Thus, the early and rapid senescence of pistils is likely responsible for the decreased pistil receptivity and inhibited pollen tube growth. These findings may be relevant for future jasmine hybridizations. They provide new insights for the development of methods to overcome reproductive barriers and may also be useful for clarifying the phylogenetic relationships among jasmine cultivars with differing petal phenotypes.
[Mh] Termos MeSH primário: Flores/genética
Germinação
Jasminum/genética
Pólen/genética
Polinização
[Mh] Termos MeSH secundário: Sobrevivência Celular
Cruzamentos Genéticos
Flores/citologia
Flores/embriologia
Flores/fisiologia
Jasminum/citologia
Jasminum/embriologia
Jasminum/fisiologia
Filogenia
Pólen/citologia
Pólen/embriologia
Pólen/fisiologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1705
[Cu] Atualização por classe:170505
[Lr] Data última revisão:
170505
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170419
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0176026


  3 / 96 MEDLINE  
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[PMID]:28353656
[Au] Autor:Yu Y; Lyu S; Chen D; Lin Y; Chen J; Chen G; Ye N
[Ad] Endereço:College of Horticulture, Key Laboratory of Tea Science, Fujian Agriculture and Forestry University, Fuzhou, Fujian 350002, China. 1130311016@fafu.edu.cn.
[Ti] Título:Volatiles Emitted at Different Flowering Stages of Jasminum sambac and Expression of Genes Related to α-Farnesene Biosynthesis.
[So] Source:Molecules;22(4), 2017 Mar 29.
[Is] ISSN:1420-3049
[Cp] País de publicação:Switzerland
[La] Idioma:eng
[Ab] Resumo:Fresh jasmine flowers have been used to make jasmine teas in China, but there has been no complete information about volatile organic compound emissions in relation to flower developmental stages and no science-based knowledge about which floral stage should be used for the infusion. This study monitored volatile organic compounds emitted from living flowers of (L.) Ait. 'Bifoliatum' at five developmental stages and also from excised flowers. Among the compounds identified, α-farnesene, linalool, and benzyl acetate were most abundant. Since α-farnesene is synthesized through the Mevalonate pathway, four genes encoding 3-hydroxy-3-methylglutaryl coenzyme A synthase, 3-hydroxy-3-methylglutaryl coenzyme A reductase (HMGR), farnesyl pyrophosphate synthase, and terpene synthase were isolated. Their expression patterns in living flowers at the five stages and in excised flowers coincided with the emission patterns of α-farnesene. Application of lovastatin, a HMGR inhibitor, significantly reduced the expression of the genes and greatly decreased the emission of α-farnesene. The sweet scent was diminished from lovastatin-treated flowers as well. These results indicate that α-farnesene is an important compound emitted from jasmine flowers, and its emission patterns suggest that flowers at the opening stage or flower buds 8 h after excision should be used for the infusion of tea leaves.
[Mh] Termos MeSH primário: Flores/crescimento & desenvolvimento
Jasminum/química
Proteínas de Plantas/metabolismo
Sesquiterpenos/metabolismo
Compostos Orgânicos Voláteis/análise
[Mh] Termos MeSH secundário: Flores/química
Regulação da Expressão Gênica no Desenvolvimento/efeitos dos fármacos
Regulação da Expressão Gênica de Plantas/efeitos dos fármacos
Jasminum/enzimologia
Lovastatina/farmacologia
Redes e Vias Metabólicas/efeitos dos fármacos
Óleos Vegetais/análise
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Plant Oils); 0 (Plant Proteins); 0 (Sesquiterpenes); 0 (Volatile Organic Compounds); 502-61-4 (alpha-farnesene); 9LHU78OQFD (Lovastatin)
[Em] Mês de entrada:1705
[Cu] Atualização por classe:170518
[Lr] Data última revisão:
170518
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170330
[St] Status:MEDLINE


  4 / 96 MEDLINE  
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[PMID]:28256049
[Au] Autor:Oliveira AP; Sá I; Pereira DM; Gonçalves RF; Andrade PB; Valentão P
[Ad] Endereço:REQUIMTE/LAQV, Laboratório de Farmacognosia, Departamento de Química, Faculdade de Farmácia, Universidade do Porto, R. Jorge Viterbo Ferreira, no. 228, PT-4050-313, Porto.
[Ti] Título:Exploratory Studies on the in Vitro Anti-inflammatory Potential of Two Herbal Teas (Annona muricata L. and Jasminum grandiflorum L.), and Relation with Their Phenolic Composition.
[So] Source:Chem Biodivers;14(6), 2017 Jun.
[Is] ISSN:1612-1880
[Cp] País de publicação:Switzerland
[La] Idioma:eng
[Ab] Resumo:The need of new anti-inflammatory drugs has led to the search for safer and more potent molecules in distinct sources, such as natural products. This work aimed to explore the anti-inflammatory potential of aqueous extracts from two herbal teas (Annona muricata L. and Jasminum grandiflorum L.) in RAW 264.7 macrophages cells and in cell-free assays. Furthermore, the phenolic composition of both extracts and of their hydrolysates was characterized by HPLC-DAD, in order to establish possible relationships with the biological activity. In a general way, A. muricata displayed a stronger capacity to inhibit nitric oxide (NO) production and the activity of phospholipase A (PLA ), displaying an IC value of 142 µg/ml against this enzyme. A deeper look at phenolic compounds revealed that aglycones had more capacity to inhibit NO and PLA than their corresponding glycosides, quercetin being clearly the most potent one (IC  = 7.47 and 1.36 µm, respectively). In addition, 5-O-caffeoylquinic acid, at 1.56 µm, could also inhibit PLA (ca. 35%). Our findings suggest that the consumption of both herbal teas may be a preventive approach to inflammatory disorders.
[Mh] Termos MeSH primário: Anti-Inflamatórios/isolamento & purificação
Chás de Ervas
[Mh] Termos MeSH secundário: Animais
Annona/química
Anti-Inflamatórios/farmacologia
Sistema Livre de Células/efeitos dos fármacos
Jasminum/química
Camundongos
Óxido Nítrico/antagonistas & inibidores
Fenóis/análise
Fenóis/farmacologia
Inibidores de Fosfolipase A2
Extratos Vegetais
Células RAW 264.7
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Anti-Inflammatory Agents); 0 (Phenols); 0 (Phospholipase A2 Inhibitors); 0 (Plant Extracts); 0 (Teas, Herbal); 31C4KY9ESH (Nitric Oxide)
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170822
[Lr] Data última revisão:
170822
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170304
[St] Status:MEDLINE
[do] DOI:10.1002/cbdv.201700002


  5 / 96 MEDLINE  
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[PMID]:28242384
[Au] Autor:Tadiwos Y; Nedi T; Engidawork E
[Ad] Endereço:Haramaya University, School of Pharmacy, College of Medical and Health Sciences, Harar P.O.Box 235, Ethiopia. Electronic address: ytadios@yahoo.com.
[Ti] Título:Analgesic and anti-inflammatory activities of 80% methanol root extract of Jasminum abyssinicum Hochst. ex. Dc. (Oleaceae) in mice.
[So] Source:J Ethnopharmacol;202:281-289, 2017 Apr 18.
[Is] ISSN:1872-7573
[Cp] País de publicação:Ireland
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Pain and inflammation are associated with the pathophysiology of various clinical conditions. Most analgesic and anti-inflammatory drugs available in the market present a wide range of problems. The current study was aimed at investigating the analgesic and anti-inflammatory activity of 80% methanol extract of J. abyssinicum root. METHODS: The analgesic activity was determined using tail-flick test and acetic acid induced writhing, whereas anti-inflammatory activity was determined by carrageenan induced paw edema and formalin induced pedal edema, carried out in vivo. The test group received three different doses of the extract (50mg/kg, 100mg/kg and 200mg/kg) orally. The positive control group received diclofenac (10mg/kg), aspirin (100mg/kg or 150mg/kg) or morphine (20mg/kg) orally. The negative control group received vehicle (2% Tween 80, 10ml/kg) orally. Furthermore, preliminary phytochemical screening was carried out. RESULTS: Oral administration of J. abbysinicum 80% methanol extract (at all doses) significantly (p<0.001) inhibit pain sensation in the pain models. Similarly, the extract demonstrated anti-inflammatory effect in the inflammation models in mice. Preliminary phytochemical screening showed the presence of saponins, flavonoids, terpenoids, triterpenens and glycosides. CONCLUSION: The data obtained from the present study indicates that the extract possessed a significant analgesic and anti-inflammatory activity, upholding the folkloric use of the plant.
[Mh] Termos MeSH primário: Analgésicos/farmacologia
Anti-Inflamatórios não Esteroides/farmacologia
Jasminum/química
Extratos Vegetais/farmacologia
Raízes de Plantas/química
[Mh] Termos MeSH secundário: Analgésicos Opioides/farmacologia
Animais
Diclofenaco/farmacologia
Relação Dose-Resposta a Droga
Edema/prevenção & controle
Jasminum/toxicidade
Masculino
Metanol
Camundongos
Morfina/farmacologia
Medição da Dor/efeitos dos fármacos
Extratos Vegetais/química
Extratos Vegetais/toxicidade
Solventes
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Analgesics); 0 (Analgesics, Opioid); 0 (Anti-Inflammatory Agents, Non-Steroidal); 0 (Plant Extracts); 0 (Solvents); 144O8QL0L1 (Diclofenac); 76I7G6D29C (Morphine); Y4S76JWI15 (Methanol)
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170824
[Lr] Data última revisão:
170824
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170301
[St] Status:MEDLINE


  6 / 96 MEDLINE  
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[PMID]:28167035
[Au] Autor:Bera P; Mukherjee C; Mitra A
[Ad] Endereço:Natural Product Biotechnology Group, Agricultural and Food Engineering Department, Indian Institute of Technology Kharagpur, Kharagpur 721 302, India.
[Ti] Título:Enzymatic production and emission of floral scent volatiles in Jasminum sambac.
[So] Source:Plant Sci;256:25-38, 2017 Mar.
[Is] ISSN:1873-2259
[Cp] País de publicação:Ireland
[La] Idioma:eng
[Ab] Resumo:Floral scent composed of low molecular weight volatile organic compounds. The sweet fragrance of any evening blooming flower is dominated by benzenoid and terpenoid volatile compounds. Floral scent of Jasminum sambac (Oleaceae) includes three major benzenoid esters - benzylacetate, methylbenzoate, and methylsalicylate and three major terpene compounds viz. (E)-ß-ocimene, linalool and α-farnesene. We analyzed concentrations and emission rates of benzenoids and terpenoids during the developmental stages of J. sambac flower. In addition to spatial emission from different floral parts, we studied the time-course mRNA accumulations of phenylalanine ammonia-lyase (PAL) and the two representative genes of terpenoid pathway, namely 1-deoxy-d-xylulose 5-phosphate reductoisomerase (DXR) and terpene synthase (TPS). Further, in vitro activities of several enzymes of phenylpropanoid/benzenoid pathway viz., PAL and acetyl-coenzyme A: benzylalcohol acetyltransferase (BEAT), S-adenosyl-l-methionine: benzoic acid carboxyl methyl transferase (BAMT) and S-adenosyl-l-methionine: salicylic acid carboxyl methyltransferase (SAMT) were studied. All the above enzyme activities along with the in vitro activities of DXR and TPS were found to follow a certain rhythm as observed in the emission of different benzenoid and terpenoid compounds. Linalool emission peaked after petal opening and coincided with maximal expression of JsTPS gene as evidenced from RT-PCR analyses (semi-quantitative). The maximum transcript accumulation of this gene was observed in flower petals, indicating that the petals of J. sambac flower play an important role as a major contributor of volatile precursors. The transcripts accumulation of JsDXR and JsTPS in different developmental stages and in different floral part showed that emissions of terpenoid volatiles in J. sambac flower are partially regulated at transcription levels.
[Mh] Termos MeSH primário: Flores/metabolismo
Jasminum/metabolismo
Odorantes
Terpenos/metabolismo
Compostos Orgânicos Voláteis/metabolismo
[Mh] Termos MeSH secundário: Aldose-Cetose Isomerases/genética
Aldose-Cetose Isomerases/metabolismo
Alquil e Aril Transferases/genética
Alquil e Aril Transferases/metabolismo
Flores/enzimologia
Jasminum/enzimologia
Jasminum/genética
Metiltransferases/metabolismo
Fenilalanina Amônia-Liase/genética
Fenilalanina Amônia-Liase/metabolismo
Proteínas de Plantas/genética
Proteínas de Plantas/metabolismo
RNA Mensageiro/metabolismo
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Plant Proteins); 0 (RNA, Messenger); 0 (Terpenes); 0 (Volatile Organic Compounds); EC 1.1.1.267 (1-deoxy-D-xylulose 5-phosphate reductoisomerase); EC 2.1.1.- (Methyltransferases); EC 2.5.- (Alkyl and Aryl Transferases); EC 2.5.1.- (terpene synthase); EC 4.3.1.24 (Phenylalanine Ammonia-Lyase); EC 5.3.1.- (Aldose-Ketose Isomerases)
[Em] Mês de entrada:1704
[Cu] Atualização por classe:170417
[Lr] Data última revisão:
170417
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170208
[St] Status:MEDLINE


  7 / 96 MEDLINE  
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[PMID]:27902183
[Au] Autor:Techo S; Miyashita M; Shibata C; Tanaka N; Wisetkhan P; Visessanguan W; Tanasupawat S
[Ad] Endereço:1​Department of Biochemistry and Microbiology, Faculty of Pharmaceutical Sciences, Chulalongkorn University, Bangkok 10330, Thailand.
[Ti] Título:Lactobacillus ixorae sp. nov., isolated from a flower (West-Indian jasmine).
[So] Source:Int J Syst Evol Microbiol;66(12):5500-5505, 2016 Dec.
[Is] ISSN:1466-5034
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:A Gram-stain-positive, lactic acid bacterium, strain Ru20-1T, was isolated from a flower (West-Indian jasmine) collected from Kalasin province, Thailand. A polyphasic approach was used to determine the taxonomic position of this strain. Studies of morphological and biochemical characteristics revealed that strain Ru20-1T belonged to the genus Lactobacillus. The strain was heterofermentative, non-spore-forming and rod-shaped. It produced dl-lactic acid. Based on 16S rRNA gene sequence similarity, this strain was closely related to Lactobacillus lindneri LMG 14528T (96.8 %), Lactobacillus sanfranciscensis NRIC 1548T (95.4 %) and Lactobacillus florum NRIC 0771T (95.2 %), respectively. In addition, the pheS gene sequence of strain Ru20-1T was closely related to those of L. sanfranciscensis NRIC 1548T (92.0 %), L. lindneri LMG 14528T (89.0 %) and L. florum NRIC 0771T(85.0 %). Phylogenetic analysis indicated that strain Ru20-1T was clearly separated from closely related species of the genus Lactobacillus. The DNA G+C content of strain Ru20-1T was 47.8 mol %. The cell-wall peptidoglycan type was l-Lys-d-Asp. The major cellular fatty acids were C18 : 1ω9c, C20 : 0, C20 : 1ω9c and summed feature 7 (unknown 18.846 and/or C19 : 1ω6c and/or C19 : 0 cyclo). On the basis of the data provided, strain Ru20-1T represents a novel species of the genus Lactobacillus, for which the name Lactobacillus ixorae sp. nov. is proposed. The type strain is Ru20-1T (=LMG 29008T=NBRC 111239T=PCU 346T=TISTR 2381T).
[Mh] Termos MeSH primário: Flores/microbiologia
Jasminum/microbiologia
Lactobacillus/classificação
Filogenia
[Mh] Termos MeSH secundário: Bacillus coagulans
Técnicas de Tipagem Bacteriana
Composição de Bases
DNA Bacteriano/genética
Ácidos Graxos/química
Fermentação
Ácido Láctico/biossíntese
Lactobacillus/genética
Lactobacillus/isolamento & purificação
Hibridização de Ácido Nucleico
Peptidoglicano/química
RNA Ribossômico 16S/genética
Análise de Sequência de DNA
Tailândia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (DNA, Bacterial); 0 (Fatty Acids); 0 (Peptidoglycan); 0 (RNA, Ribosomal, 16S); 33X04XA5AT (Lactic Acid)
[Em] Mês de entrada:1707
[Cu] Atualização por classe:170817
[Lr] Data última revisão:
170817
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161201
[St] Status:MEDLINE
[do] DOI:10.1099/ijsem.0.001547


  8 / 96 MEDLINE  
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[PMID]:27297841
[Au] Autor:Ye Q; Jin X; Wei S; Zheng G; Li X
[Ad] Endereço:Fujian Provincial Key Laboratory of Subtropical Plant Physiology and Biochemistry, Science Building, Fujian Institute of Subtropical Botany, 780-800, Jiahe Rd, Xiamen 361006, China.
[Ti] Título:Effect of Subcritical Fluid Extraction on the High Quality of Headspace Oil from Jasminum sambac (L.) Aiton.
[So] Source:J AOAC Int;99(3):725-9, 2016 May.
[Is] ISSN:1060-3271
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Subcritical fluid extraction (SFE), as a novel method, was applied to investigate the yield, quality, and sensory evaluation of headspace oil from Jasminum sambac (L.) Aiton in comparison with petroleum ether extraction (PEE). The results indicated that the yield of the headspace oil using SFE was significantly higher (P < 0.05) than when using PEE. SFE contributed to obtaining alcohols and ethers, prevented the thermal reaction of terpenes, and reduced α-caryophyllene and ß-caryophyllene in the headspace oil. The contents of linalool (21.90%) and benzyl acetate (16.31%) were higher via SFE than PEE. In addition, the sensory evaluation of SFE was superior to PEE, indicating a fresh, jasmine-like odor and green-yellow color. Thus, SFE is an improved method for obtaining natural headspace oil from jasmine flowers.
[Mh] Termos MeSH primário: Cromatografia com Fluido Supercrítico
Jasminum/química
Óleos Vegetais/química
Óleos Vegetais/isolamento & purificação
[Mh] Termos MeSH secundário: Produtos Biológicos/química
Produtos Biológicos/isolamento & purificação
Flores/química
Cromatografia Gasosa-Espectrometria de Massas
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Biological Products); 0 (Plant Oils)
[Em] Mês de entrada:1703
[Cu] Atualização por classe:170306
[Lr] Data última revisão:
170306
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160615
[St] Status:MEDLINE
[do] DOI:10.5740/jaoacint.15-0308


  9 / 96 MEDLINE  
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[PMID]:27193820
[Au] Autor:Baatartsogt T; Bui VN; Trinh DQ; Yamaguchi E; Gronsang D; Thampaisarn R; Ogawa H; Imai K
[Ad] Endereço:Diagnostic Center for Animal Health and Food Safety, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido 080-8555, Japan.
[Ti] Título:High antiviral effects of hibiscus tea extract on the H5 subtypes of low and highly pathogenic avian influenza viruses.
[So] Source:J Vet Med Sci;78(9):1405-1411, 2016 Oct 01.
[Is] ISSN:1347-7439
[Cp] País de publicação:Japan
[La] Idioma:eng
[Ab] Resumo:Viral neuraminidase inhibitors are widely used as synthetic anti-influenza drugs for the prevention and treatment of influenza. However, drug-resistant influenza A virus variants, including H5N1 highly pathogenic avian influenza viruses (HPAIVs), have been reported. Therefore, the discovery of novel and effective antiviral agents is warranted. We screened the antiviral effects of 11 herbal tea extracts (hibiscus, black tea, tencha, rosehip tea, burdock tea, green tea, jasmine tea, ginger tea, lavender tea, rose tea and oak tea) against the H5N1 HPAIV in vitro. Among the tested extracts, only the hibiscus extract and its fractionated extract (frHibis) highly and rapidly reduced the titers of all H5 HPAIVs and low pathogenic AIVs (LPAIVs) used in the pre-treatment tests of Madin-Darby canine kidney (MDCK) cells that were inoculated with a mixture of the virus and the extract. Immunogold electron microscopy showed that anti-H5 monoclonal antibodies could not bind to the deformed H5 virus particles pretreated with frHibis. In post-treatment tests of MDCK cells cultured in the presence of frHibis after infection with H5N1 HPAIV, the frHibis inhibited viral replication and the expression of viral antigens and genes. Among the plants tested, hibiscus showed the most prominent antiviral effects against both H5 HPAIV and LPAIV.
[Mh] Termos MeSH primário: Althaea
Antivirais/farmacologia
Hibiscus
Vírus da Influenza A Subtipo H5N1/efeitos dos fármacos
Vírus da Influenza A Subtipo H5N2/efeitos dos fármacos
Vírus da Influenza A Subtipo H5N8/efeitos dos fármacos
Extratos Vegetais/farmacologia
Chá
[Mh] Termos MeSH secundário: Animais
Camellia sinensis
Cães
Vírus da Influenza A Subtipo H5N1/fisiologia
Vírus da Influenza A Subtipo H5N2/fisiologia
Vírus da Influenza A Subtipo H5N8/fisiologia
Jasminum
Lavandula
Células Madin Darby de Rim Canino/virologia
Microscopia Eletrônica
Quercus
Rosa
Rubus
Replicação Viral/efeitos dos fármacos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Antiviral Agents); 0 (Plant Extracts); 0 (Tea)
[Em] Mês de entrada:1706
[Cu] Atualização por classe:170622
[Lr] Data última revisão:
170622
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160520
[St] Status:MEDLINE


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[PMID]:27068169
[Au] Autor:Tang Y; Gao F; Yang Z; Wu Z; Yang L
[Ad] Endereço:Fujian Key Lab of Plant Virology, Institute of Plant Virology, Fujian Agriculture and Forestry University, Fuzhou, 350002, China.
[Ti] Título:Complete genome analysis of jasmine virus T from Jasminum sambac in China.
[So] Source:Arch Virol;161(7):2033-6, 2016 Jul.
[Is] ISSN:1432-8798
[Cp] País de publicação:Austria
[La] Idioma:eng
[Ab] Resumo:The genome of a potyvirus (isolate JaVT_FZ) recovered from jasmine (Jasminum sambac L.) showing yellow ringspot symptoms in Fuzhou, China, was sequenced. JaVT_FZ is closely related to seven other potyviruses with completely sequenced genomes, with which it shares 66-70 % nucleotide and 52-56 % amino acid sequence identity. However, the coat protein (CP) gene shares 82-92 % nucleotide and 90-97 % amino acid sequence identity with those of two partially sequenced potyviruses, named jasmine potyvirus T (JaVT-jasmine) and jasmine yellow mosaic potyvirus (JaYMV-India), respectively. This suggests that JaVT_FZ, JaVT-jasmine and JaYMV-India should be regarded as members of a single potyvirus species, for which the name "Jasmine virus T" has priority.
[Mh] Termos MeSH primário: Genoma Viral
Jasminum/virologia
Doenças das Plantas/virologia
Potyvirus/genética
Potyvirus/isolamento & purificação
[Mh] Termos MeSH secundário: Sequência de Bases
China
Dados de Sequência Molecular
Fases de Leitura Aberta
Potyvirus/classificação
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1702
[Cu] Atualização por classe:170203
[Lr] Data última revisão:
170203
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160413
[St] Status:MEDLINE
[do] DOI:10.1007/s00705-016-2811-1



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