Base de dados : MEDLINE
Pesquisa : B01.650.940.800.575.912.250.583.670.270 [Categoria DeCS]
Referências encontradas : 12 [refinar]
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  1 / 12 MEDLINE  
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[PMID]:28704790
[Au] Autor:Bigagli E; Cinci L; D'Ambrosio M; Luceri C
[Ad] Endereço:Department of Neuroscience, Psychology, Drug Research and Child Health, NEUROFARBA, Section of Pharmacology and Toxicology, University of Florence, Viale G. Pieraccini 6, Florence, Italy.
[Ti] Título:Pharmacological activities of an eye drop containing Matricaria chamomilla and Euphrasia officinalis extracts in UVB-induced oxidative stress and inflammation of human corneal cells.
[So] Source:J Photochem Photobiol B;173:618-625, 2017 Aug.
[Is] ISSN:1873-2682
[Cp] País de publicação:Switzerland
[La] Idioma:eng
[Ab] Resumo:Ultraviolet B (UVB) exposure is a risk factor for corneal damage resulting in oxidative stress, inflammation and cell death. The aim of this study was to investigate the potential protective effects of a commercial eye drop (Dacriovis™) containing Matricaria chamomilla and Euphrasia officinalis extracts on human corneal epithelial cells (HCEC-12) against UVB radiation-induced oxidative stress and inflammation as well as the underlying mechanisms. The antioxidant potential of the eye drops was evaluated by measuring the ferric reducing antioxidant power and the total phenolic content by Folin-Ciocalteu reagent. HCEC-12 cells were exposed to UVB radiation and treated with the eye drops at various concentrations. Cell viability, wound healing assay, reactive oxygen species (ROS) levels, protein and lipid oxidative damage and COX-2, IL-1ß, iNOS, SOD-2, HO-1 and GSS gene expression, were assessed. Eye drops were able to protect corneal epithelial cells from UVB-induced cell death and ameliorated the wound healing; the eye drops exhibited a strong antioxidant activity, decreasing ROS levels and protein and lipid oxidative damage. Eye drops also exerted anti-inflammatory activities by decreasing COX-2, IL-1ß, iNOS expression, counteracted UVB-induced GSS and SOD-2 expression and restored HO-1 expression to control levels. These findings suggest that an eye drop containing Matricaria chamomilla and Euphrasia officinalis extracts exerts positive effects against UVB induced oxidative stress and inflammation and may be useful in protecting corneal epithelial cells from UVB exposure.
[Mh] Termos MeSH primário: Anti-Inflamatórios/farmacologia
Euphrasia/química
Matricaria/química
Soluções Oftálmicas/farmacologia
Estresse Oxidativo/efeitos dos fármacos
Exsudatos de Plantas/química
Raios Ultravioleta
[Mh] Termos MeSH secundário: Anti-Inflamatórios/química
Antioxidantes/química
Linhagem Celular
Sobrevivência Celular/efeitos dos fármacos
Sobrevivência Celular/efeitos da radiação
Córnea/citologia
Córnea/efeitos dos fármacos
Córnea/metabolismo
Ciclo-Oxigenase 2/genética
Ciclo-Oxigenase 2/metabolismo
Euphrasia/metabolismo
Expressão Gênica/efeitos dos fármacos
Expressão Gênica/efeitos da radiação
Heme Oxigenase-1/metabolismo
Seres Humanos
Inflamação/patologia
Inflamação/prevenção & controle
Interleucina-1beta/genética
Interleucina-1beta/metabolismo
Matricaria/metabolismo
Óxido Nítrico Sintase Tipo II/genética
Óxido Nítrico Sintase Tipo II/metabolismo
Soluções Oftálmicas/química
Estresse Oxidativo/efeitos da radiação
Carbonilação Proteica/efeitos dos fármacos
Carbonilação Proteica/efeitos da radiação
Espécies Reativas de Oxigênio/metabolismo
Superóxido Dismutase/metabolismo
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Anti-Inflammatory Agents); 0 (Antioxidants); 0 (Interleukin-1beta); 0 (Ophthalmic Solutions); 0 (Plant Exudates); 0 (Reactive Oxygen Species); EC 1.14.13.39 (Nitric Oxide Synthase Type II); EC 1.14.14.18 (HMOX1 protein, human); EC 1.14.14.18 (Heme Oxygenase-1); EC 1.14.99.1 (Cyclooxygenase 2); EC 1.14.99.1 (PTGS2 protein, human); EC 1.15.1.1 (Superoxide Dismutase); EC 1.15.1.1 (superoxide dismutase 2)
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171010
[Lr] Data última revisão:
171010
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170714
[St] Status:MEDLINE


  2 / 12 MEDLINE  
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[PMID]:28233528
[Au] Autor:Mari A; Ciocarlan A; Aiello N; Scartezzini F; Pizza C; D'Ambrosio M
[Ad] Endereço:Dipartimento di Farmacia, Università degli Studi di Salerno, 84084 Fisciano (SA), Italy.
[Ti] Título:Research survey on iridoid and phenylethanoid glycosides among seven populations of Euphrasia rostkoviana Hayne from the Alps.
[So] Source:Phytochemistry;137:72-80, 2017 May.
[Is] ISSN:1873-3700
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:The traditional use of extracts of Euphrasia rostkoviana to relieve ocular inflammation or infections is well documented and supported by clinical studies. Various classes of chemical compounds such as iridoids, phenylethanoids, flavonoids and hydroxycinnamic acids have been reported. The present work aims to assess the chemical diversity among seven populations of Euphrasia rostkoviana found in northern Italy. A meticulous separation of components led to the isolation and structural characterization of two previously unrecorded phenylethanoids methoxycrassifolioside and deoxycrassifolioside and one previously undescribed terpene glucoside (1E,6E)-8-hydroxy-3,7-dimethyl-octa-1,6-dienyl 1-O-ß-D-glucopyranoside. We have also identified known phenylethanoids and iridoids that are reported in this genus for the first time. Finally, a targeted quantitative analysis for the standardization of herbal preparations revealed that iridoids occur in all populations whereas the presence and the levels of rutin and phenylethanoids are highly variable.
[Mh] Termos MeSH primário: Euphrasia/química
Glicosídeos/química
Iridoides/química
[Mh] Termos MeSH secundário: Flavonoides/química
Flavonoides/isolamento & purificação
Glucosídeos/química
Glucosídeos/isolamento & purificação
Glicosídeos/isolamento & purificação
Iridoides/isolamento & purificação
Itália
Estrutura Molecular
Compostos Fitoquímicos/química
Compostos Fitoquímicos/isolamento & purificação
Componentes Aéreos da Planta/química
Extratos Vegetais/química
Plantas Medicinais/química
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Flavonoids); 0 (Glucosides); 0 (Glycosides); 0 (Iridoids); 0 (Phytochemicals); 0 (Plant Extracts)
[Em] Mês de entrada:1704
[Cu] Atualização por classe:170407
[Lr] Data última revisão:
170407
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170225
[St] Status:MEDLINE


  3 / 12 MEDLINE  
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[PMID]:27039891
[Au] Autor:Lorenz P; Knittel DN; Conrad J; Lotter EM; Heilmann J; Stintzing FC; Kammerer DR
[Ad] Endereço:Department of Analytical Development & Research, Section Phytochemical Research, WALA Heilmittel GmbH, Dorfstr. 1, DE-73087, Bad Boll/Eckwälden. peter.lorenz@wala.de.
[Ti] Título:1-Acetyl-3-[(3R)-hydroxyfatty acyl]glycerols: Lipid Compounds from Euphrasia rostkoviana Hayne and E. tetraquetra (Bréb.) Arrond.
[So] Source:Chem Biodivers;13(5):602-12, 2016 May.
[Is] ISSN:1612-1880
[Cp] País de publicação:Switzerland
[La] Idioma:eng
[Ab] Resumo:Five homologous acetylated acylglycerols of 3-hydroxyfatty acids (chain lengths C(14) - C(18)), named euphrasianins A - E, were characterized for the first time in Euphrasia rostkoviana Hayne (Orobanchaceae) by gas chromatography/mass spectrometry (GC/MS) and high-performance liquid chromatography/atmospheric pressure chemical ionization-mass spectrometry (HPLC/APCI-MS(n) ). In addition to mass spectrometric data, structures of euphrasianins were verified via a three-step total synthesis of one representative homologue (euphrasianin A). The structure of the latter was confirmed by 1D- and 2D-NMR experiments as well as high-resolution electrospray ionization-mass spectrometry (HR-ESI-MS). The absolute configuration of the 3-hydroxyfatty acid moiety at C(3) was found to be R in the natural euphrasianins, which was determined by alkaline hydrolysis and methylation of a purified fraction, followed by chiral GC analysis. Furthermore, in extracts of Euphrasia tetraquetra (Bréb.) Arrond. euphrasianins C and E were detected exclusively, indicating that this subclass of lipid constituents is possibly valuable for fingerprinting methods.
[Mh] Termos MeSH primário: Euphrasia/química
Glicerol/análogos & derivados
Glicerol/isolamento & purificação
Lipídeos/isolamento & purificação
Orobanchaceae/química
Extratos Vegetais/isolamento & purificação
[Mh] Termos MeSH secundário: Cromatografia Líquida de Alta Pressão
Cromatografia Gasosa-Espectrometria de Massas
Glicerol/química
Lipídeos/química
Espectroscopia de Ressonância Magnética
Estrutura Molecular
Extratos Vegetais/química
Espectrometria de Massas por Ionização por Electrospray
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Lipids); 0 (Plant Extracts); PDC6A3C0OX (Glycerol)
[Em] Mês de entrada:1701
[Cu] Atualização por classe:170113
[Lr] Data última revisão:
170113
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160405
[St] Status:MEDLINE
[do] DOI:10.1002/cbdv.201500233


  4 / 12 MEDLINE  
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[PMID]:20179964
[Au] Autor:Tesitel J; Plavcová L; Cameron DD
[Ad] Endereço:Department of Botany, Faculty of Science, University of South Bohemia, Ceske Budejovice, Czech Republic. jakub.tesitel@prf.jcu.cz
[Ti] Título:Heterotrophic carbon gain by the root hemiparasites, Rhinanthus minor and Euphrasia rostkoviana (Orobanchaceae).
[So] Source:Planta;231(5):1137-44, 2010 Apr.
[Is] ISSN:1432-2048
[Cp] País de publicação:Germany
[La] Idioma:eng
[Ab] Resumo:Hemiparasitic plants gain virtually all mineral nutrients and water from their host plant whilst organic carbon is provided, at least in part, by their own photosynthetic activity, although their rates of assimilation are substantially lower than that found in non-parasitic plants. Hence, hemiparasites must gain at least some of their organic carbon heterotrophically from the host plant. Despite this, heterotrophic carbon gain by root hemiparasites has been investigated only for a few genera. We investigated heterotrophic carbon gain by two root hemiparasites, Rhinanthus minor L. and Euphrasia rostkoviana Hayne (Orobanchaceae), using natural abundance stable isotope (delta(13)C) profiles of both parasites attached to C(3) (wheat) and C(4) (maize) hosts coupled to a linear two-source isotope-mixing model to estimate the percentage of carbon in the parasite that was derived from the host. Both R. minor and E. rostkoviana attached to maize hosts were significantly more enriched in (13)C than those attached to wheat hosts with R. minor becoming more enriched in (13)C than E. rostkoviana. The natural abundance (13)C profiles of both parasites were not significantly different from their wheat hosts, but were less enriched in (13)C than maize hosts. Using a linear two-source isotope-mixing model, we estimated that R. minor and E. rostkoviana adult plants derive c. 50 and 25% of their carbon from their hosts, respectively. In light of these results, we hypothesise that repeatedly observed negative effect of competition for light on hemiparasites acts predominantly in early ontogenetic stages when parasites grow unattached or the abstraction of host nutrients is less effective.
[Mh] Termos MeSH primário: Carbono/metabolismo
Processos Heterotróficos/fisiologia
Orobanchaceae/fisiologia
Raízes de Plantas/parasitologia
Triticum/parasitologia
Zea mays/parasitologia
[Mh] Termos MeSH secundário: Biomassa
Isótopos de Carbono
Euphrasia/fisiologia
Interações Hospedeiro-Parasita
Fotossíntese
Plantago/crescimento & desenvolvimento
Plantago/parasitologia
Triticum/crescimento & desenvolvimento
Zea mays/crescimento & desenvolvimento
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Carbon Isotopes); 7440-44-0 (Carbon)
[Em] Mês de entrada:1006
[Cu] Atualização por classe:171005
[Lr] Data última revisão:
171005
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:100225
[St] Status:MEDLINE
[do] DOI:10.1007/s00425-010-1114-0


  5 / 12 MEDLINE  
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[PMID]:19526677
[Au] Autor:Blazics B; Alberti A; Kéry A
[Ad] Endereço:Semmelweis Egyetem, Farmakognózia Intézet, Budapest, Ulloi u. 26.-1085. blazics@gmail.com
[Ti] Título:[Antioxidant activity of different phenolic fractions separated from Euphrasia rostkoviana Hayne].
[Ti] Título:Az Euphrasia rostkoviana Hayne fenoloid tartalmú frakcióinak antioxidáns értékelése..
[So] Source:Acta Pharm Hung;79(1):11-6, 2009.
[Is] ISSN:0001-6659
[Cp] País de publicação:Hungary
[La] Idioma:hun
[Ab] Resumo:Euphrasia rostkoviana Hayne (Eyebright) is a valuable part of the traditional folk medicine as an anti-inflammatory herb since centuries. Since oxidative stress may underlie as a key feature of inflammatory process, the methanolic extract ofEuphrasia rostkoviana Hayne (eyebright) and its methanolic fractions were evaluated for antioxidant activity by the use of ABTS and DPPH decolorization assays. Fractionation of the Soxhlet extract was accomplished by polyamide column chromatography. For chemical characterisation HPLC-DAD-MS/MS was used. Fraction 1., dominated by a glycosilated caffeic acid derivative, exhibited the strongest antioxidant activity in DPPH and ABTS assays, IC50: 11.88 microg/ml and 4.24 microg/ml, respectively, which are notable results if compared to the investigated standards. Fractions of flavonoid glycosides proved to have similarly strong, but lower effect. The scavenging reaction of the two radical cations were comparable, IC50 results were differing, while precision not.
[Mh] Termos MeSH primário: Antioxidantes/farmacologia
Euphrasia/química
Fenóis/farmacologia
[Mh] Termos MeSH secundário: Antioxidantes/isolamento & purificação
Compostos de Bifenilo
Ácidos Cafeicos/isolamento & purificação
Ácidos Cafeicos/farmacologia
Cromatografia Líquida de Alta Pressão
Fenóis/isolamento & purificação
Picratos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Antioxidants); 0 (Biphenyl Compounds); 0 (Caffeic Acids); 0 (Phenols); 0 (Picrates); DFD3H4VGDH (1,1-diphenyl-2-picrylhydrazyl); U2S3A33KVM (caffeic acid)
[Em] Mês de entrada:0907
[Cu] Atualização por classe:161125
[Lr] Data última revisão:
161125
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:090617
[St] Status:MEDLINE


  6 / 12 MEDLINE  
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[PMID]:19364226
[Au] Autor:Weidemann G; Tangen JM; Lovibond PF; Mitchell CJ
[Ad] Endereço:School of Psychology, University of New South Wales, Sydney, New South Wales, Australia. G.Weidemann@unsw.edu.au
[Ti] Título:Is Perruchet's dissociation between eyeblink conditioned responding and outcome expectancy evidence for two learning systems?
[So] Source:J Exp Psychol Anim Behav Process;35(2):169-76, 2009 Apr.
[Is] ISSN:0097-7403
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:P. Perruchet (1985b) showed a double dissociation of conditioned responses (CRs) and expectancy for an airpuff unconditioned stimulus (US) in a 50% partial reinforcement schedule in human eyeblink conditioning. In the Perruchet effect, participants show an increase in CRs and a concurrent decrease in expectancy for the airpuff across runs of reinforced trials; conversely, participants show a decrease in CRs and a concurrent increase in expectancy for the airpuff across runs of nonreinforced trials. Three eyeblink conditioning experiments investigated whether the linear trend in eyeblink CRs in the Perruchet effect is a result of changes in associative strength of the conditioned stimulus (CS), US sensitization, or learning the precise timing of the US. Experiments 1 and 2 demonstrated that the linear trend in eyeblink CRs is not the result of US sensitization. Experiment 3 showed that the linear trend in eyeblink CRs is present with both a fixed and a variable CS-US interval and so is not the result of learning the precise timing of the US. The results are difficult to reconcile with a single learning process model of associative learning in which expectancy mediates CRs.
[Mh] Termos MeSH primário: Condicionamento Clássico/fisiologia
Condicionamento Palpebral/fisiologia
Euphrasia/fisiologia
Teoria Psicológica
Reforço (Psicologia)
[Mh] Termos MeSH secundário: Adolescente
Adulto
Aprendizagem por Associação/fisiologia
Extinção Psicológica
Feminino
Seres Humanos
Masculino
Meia-Idade
Estimulação Física/métodos
Esquema de Reforço
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Em] Mês de entrada:0906
[Cu] Atualização por classe:090414
[Lr] Data última revisão:
090414
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:090415
[St] Status:MEDLINE
[do] DOI:10.1037/a0013294


  7 / 12 MEDLINE  
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[PMID]:19296385
[Au] Autor:Petitto V; Serafini M; Ballero M; Foddai S; Stanzione A; Nicoletti M
[Ad] Endereço:Dipartimento di Biologia Vegetale, Universita di Roma La Sapienza, Rome, Italy.
[Ti] Título:Iridoids from Euphrasia genargentea, a rare Sardinian endemism.
[So] Source:Nat Prod Res;23(5):431-5, 2009.
[Is] ISSN:1478-6427
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:The phytochemical study of Euphrasia genargentea, a rare species only present in Sardinia, led to the identification of iridoid glucosides, i.e. aucubin, catalpol, mussaenosidic acid and melampyroside, which allowed chemotaxonomic considerations on the genus. On the basis of iridoid distribution in the genus, E. genargentea does not show any particular analogy with other Italian Euphrasia spp. This study is also important considering the severe risk of extinction of E. genargentea.
[Mh] Termos MeSH primário: Euphrasia/química
Iridoides/química
[Mh] Termos MeSH secundário: Itália
Estrutura Molecular
Componentes Aéreos da Planta/química
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Iridoids)
[Em] Mês de entrada:0905
[Cu] Atualização por classe:090319
[Lr] Data última revisão:
090319
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:090320
[St] Status:MEDLINE
[do] DOI:10.1080/14786410802041063


  8 / 12 MEDLINE  
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[PMID]:18555702
[Au] Autor:Gussarova G; Popp M; Vitek E; Brochmann C
[Ad] Endereço:National Centre for Biosystematics, Natural History Museum, University of Oslo, PO Box 1172 Blindern, NO-0318 Oslo, Norway. galina.gusarova@nhm.uio.no
[Ti] Título:Molecular phylogeny and biogeography of the bipolar Euphrasia (Orobanchaceae): recent radiations in an old genus.
[So] Source:Mol Phylogenet Evol;48(2):444-60, 2008 Aug.
[Is] ISSN:1095-9513
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Euphrasia includes perennial or annual green parasitic plants, and has a disjunct bipolar distribution except for one transtropical connection across the high mountains of Oceania. The disjunction is coupled with strikingly contrasting patterns of morphological diversity between the southern and northern hemispheres, making it an exciting model to study processes of evolutionary diversification which shaped present floras. We inferred the relationships among 51 species representing 14 of the 15 sections of the genus based on nrDNA ITS and cpDNA trnL intron, trnL-trnF and atpB-rbcL intergenic spacers. Maximum parsimony and Bayesian inference support monophyly of the genus and of several intrageneric groups characterized by morphology, ploidy level, and geographic range. Molecular phylogenetic dating using Bayesian "relaxed" clock methods suggests that the earliest Euphrasia radiations occurred minimum 11-8 Mya with bipolarity being achieved 7-5 Mya. Biogeographic analyses using explicit model-based approach inferred Eurasia as an ancestral area for the genus. The most parsimonious reconstruction found by a dispersal-vicariance analysis requires 17 dispersals to account for the current biogeographic pattern and supports Eurasian origin for Euphrasia. Both long-distance dispersal and across land vicariance can be invoked to explain the diversification in the genus, which experienced rapid radiations driven by new ecological opportunities of the late Pliocene and Pleistocene but also retained a set of local endemic or relict species of an earlier origin.
[Mh] Termos MeSH primário: Euphrasia/genética
Filogenia
[Mh] Termos MeSH secundário: Núcleo Celular/genética
DNA de Cloroplastos/química
DNA de Cloroplastos/genética
DNA Ribossômico/química
DNA Ribossômico/genética
Euphrasia/classificação
Variação Genética
Geografia
Dados de Sequência Molecular
Análise de Sequência de DNA
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (DNA, Chloroplast); 0 (DNA, Ribosomal)
[Em] Mês de entrada:0901
[Cu] Atualização por classe:080731
[Lr] Data última revisão:
080731
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:080617
[St] Status:MEDLINE
[do] DOI:10.1016/j.ympev.2008.05.002


  9 / 12 MEDLINE  
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[PMID]:15900830
[Ti] Título:[Eyebright. Nomen est omen].
[Ti] Título:Augentrost: Nomen est omen..
[So] Source:Praxis (Bern 1994);94(16):662, 2005 Apr 20.
[Is] ISSN:1661-8157
[Cp] País de publicação:Switzerland
[La] Idioma:ger
[Mh] Termos MeSH primário: Antroposofia
Euphrasia
Homeopatia
Fitoterapia
[Mh] Termos MeSH secundário: Adulto
Estudos de Coortes
Constipação Intestinal/tratamento farmacológico
Ensaios Clínicos Controlados como Assunto
Oftalmopatias/tratamento farmacológico
Feminino
Seres Humanos
Masculino
Distúrbios Menstruais/tratamento farmacológico
Estudos Multicêntricos como Assunto
Prostatite/tratamento farmacológico
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:0506
[Cu] Atualização por classe:080610
[Lr] Data última revisão:
080610
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:050520
[St] Status:MEDLINE


  10 / 12 MEDLINE  
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[PMID]:15316556
[Au] Autor:French GC; Ennos RA; Silverside AJ; Hollingsworth PM
[Ad] Endereço:Royal Botanic Garden Edinburgh, 20A Inverleith Row, Edinburgh, EH3 5LR, Scotland, UK.
[Ti] Título:The relationship between flower size, inbreeding coefficient and inferred selfing rate in British Euphrasia species.
[So] Source:Heredity (Edinb);94(1):44-51, 2005 Jan.
[Is] ISSN:0018-067X
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:The genus Euphrasia in Britain comprises a taxonomically complex group of self-compatible, morphologically similar, hemi-parasitic, annual plant species of high conservation importance. The 19 diploid and tetraploid taxa currently recognised show striking variation in flower size. The objective of this paper is to determine whether a relationship exists between flower size and breeding system within Euphrasia. Following a survey of flower size variation among the 19 taxa, seven diploid populations, encompassing a broad range of flower sizes, were selected for detailed study. Four nuclear microsatellite loci were used to estimate the inbreeding coefficient Fis within each population. Fis values varied from to 0.17-0.77 and showed a significant, negative correlation with flower size. These results are best explained as the consequence of variation in selfing rate among the Euphrasia populations, with selfing rate increasing as flower size decreases. The potential factors influencing breeding system evolution in Euphrasia are discussed, together with the role of autogamy in generating taxonomic complexity and facilitating lineage differentiation within the genus.
[Mh] Termos MeSH primário: Euphrasia/genética
Flores/fisiologia
Variação Genética
Endogamia
Repetições de Microssatélites
[Mh] Termos MeSH secundário: Fenótipo
Ploidias
Reino Unido
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Em] Mês de entrada:0505
[Cu] Atualização por classe:161124
[Lr] Data última revisão:
161124
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:040819
[St] Status:MEDLINE



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