Base de dados : MEDLINE
Pesquisa : B01.650.940.800.575.912.250.583.690 [Categoria DeCS]
Referências encontradas : 27 [refinar]
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  1 / 27 MEDLINE  
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[PMID]:28826029
[Au] Autor:Masondo NA; Kulkarni MG; Finnie JF; Van Staden J
[Ad] Endereço:Research Centre for Plant Growth and Development, School of Life Sciences, University of KwaZulu-Natal, Pietermaritzburg Campus, Private Bag X01, Scottsville 3209, South Africa.
[Ti] Título:Influence of biostimulants-seed-priming on Ceratotheca triloba germination and seedling growth under low temperatures, low osmotic potential and salinity stress.
[So] Source:Ecotoxicol Environ Saf;147:43-48, 2018 Jan.
[Is] ISSN:1090-2414
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:Extreme temperatures, drought and salinity stress adversely affect seed germination and seedling growth in crop species. Seed priming has been recognized as an indispensable technique in the production of stress-tolerant plants. Seed priming increases seed water content, improves protein synthesis using mRNA and DNA and repair mitochondria in seeds prior to germination. The current study aimed to determine the role of biostimulants-seed-priming during germination and seedling growth of Ceratotheca triloba (Bernh.) Hook.f. (an indigenous African leafy vegetable) under low temperature, low osmotic potential and salinity stress conditions. Ceratotheca triloba seeds were primed with biostimulants [smoke-water (SW), synthesized smoke-compound karrikinolide (KAR ), Kelpak (commercial seaweed extract), phloroglucinol (PG) and distilled water (control)] for 48h at 25°C. Thereafter, primed seeds were germinated at low temperatures, low osmotic potential and high NaCl concentrations. Low temperature (10°C) completely inhibited seed germination. However, temperature shift to 15°C improved germination. Smoke-water and KAR enhanced seed germination with SW improving seedling growth under different stress conditions. Furthermore, priming seeds with Kelpak stimulated percentage germination, while PG and the control treatment improved seedling growth at different PEG and NaCl concentrations. Generally, high concentrations of PEG and NaCl brought about detrimental effects on seed germination and seedling growth. Findings from this study show the potential role of seed priming with biostimulants in the alleviation of abiotic stress conditions during seed germination and seedling growth in C. triloba plants.
[Mh] Termos MeSH primário: Furanos/farmacologia
Germinação/efeitos dos fármacos
Pedaliaceae/efeitos dos fármacos
Piranos/farmacologia
Plântulas/efeitos dos fármacos
Sementes/efeitos dos fármacos
Estresse Fisiológico/efeitos dos fármacos
[Mh] Termos MeSH secundário: Temperatura Baixa
Secas
Osmose
Pedaliaceae/crescimento & desenvolvimento
Salinidade
Plântulas/crescimento & desenvolvimento
África do Sul
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Furans); 0 (Pyrans); 0 (karrikinolide)
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180308
[Lr] Data última revisão:
180308
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170822
[St] Status:MEDLINE


  2 / 27 MEDLINE  
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[PMID]:28772238
[Au] Autor:Ishwarya R; Vaseeharan B; Anuradha R; Rekha R; Govindarajan M; Alharbi NS; Kadaikunnan S; Khaled JM; Benelli G
[Ad] Endereço:Biomaterials and Biotechnology in Animal Health Lab, Department of Animal Health and Management, Alagappa University, Karaikudi 630004, Tamil Nadu, India.
[Ti] Título:Eco-friendly fabrication of Ag nanostructures using the seed extract of Pedalium murex, an ancient Indian medicinal plant: Histopathological effects on the Zika virus vector Aedes aegypti and inhibition of biofilm-forming pathogenic bacteria.
[So] Source:J Photochem Photobiol B;174:133-143, 2017 Sep.
[Is] ISSN:1873-2682
[Cp] País de publicação:Switzerland
[La] Idioma:eng
[Ab] Resumo:The control of Zika virus mosquito vectors and well as the development of drugs in the fight against biofilm-forming microbial pathogens, are timely and important challenges in current bionanoscience. Here we focused on the eco-friendly fabrication of Ag nanostructures using the seed extract of Pedalium murex, an ancient Indian medicinal plant. Initial confirmation of Ag nanoparticles (AgNPs) production was showed by a color change from transparent to dark brown. The UV-Visible spectrum (476nm), X-ray diffraction peaks (101, 200, 220 and 311) and Fourier transform infrared spectroscopy shed light on the production of green-capped AgNPs. Morphological structure analysis using HR-TEM showed that the AgNPs were mostly hexagonal in shape with rough edges, and a size of 20-30nm. The larvicidal potential of P. murex seed extract and AgNPs fabricated using the P. murex seed extract (Pm-AgNPs) was tested on fourth instar mosquito larvae of the Zika virus vector Aedes aegypti. Maximum efficacy was achieved by Pm-AgNPs against Ae. aegypti after 24h (LC 34.88; LC 64.56mg/ml), if compared to the P. murex seed extract. Histopathological analyses showed severe damages to the hindgut and larval muscles in NPs-treated Ae. aegypti larvae. The sub-MIC concentrations of Pm-AgNPs exhibited significant anti-biofilm activity against Gram positive (Enterococcus faecalis, Staphylococcus aureus) and Gram negative (Shigella sonnei, Pseudomonas aeruginosa) bacterial pathogens, as showed by EPS and MTP assays. Light and CLSM microscopic studies highlighted a significant impact of P. murex seed extract and Pm-synthesized AgNPs on the surface topography and architecture of bacterial biofilm, both in Gram positive and Gram negative species. Overall, results reported here contribute to the development of reliable large-scale protocols for the green fabrication of effective mosquito larvicides and biofilm inhibitors.
[Mh] Termos MeSH primário: Aedes/citologia
Bactérias/efeitos dos fármacos
Biofilmes/efeitos dos fármacos
Pedaliaceae/química
Prata/química
Prata/farmacologia
Zika virus
[Mh] Termos MeSH secundário: Animais
Química Verde
Insetos Vetores/efeitos dos fármacos
Inseticidas/química
Inseticidas/farmacologia
Larva/citologia
Nanopartículas Metálicas
Extratos Vegetais/química
Plantas Medicinais/química
Sementes/química
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Insecticides); 0 (Plant Extracts); 3M4G523W1G (Silver)
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171012
[Lr] Data última revisão:
171012
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170804
[St] Status:MEDLINE


  3 / 27 MEDLINE  
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[PMID]:27150318
[Au] Autor:Jones BO; John OO; Luke C; Ochieng A; Bassey BJ
[Ad] Endereço:Department of Ecology and Resources Management, School of Environmental Sciences, University of Venda, X0950, South Africa. Electronic address: odojones@gmail.com.
[Ti] Título:Application of mucilage from Dicerocaryum eriocarpum plant as biosorption medium in the removal of selected heavy metal ions.
[So] Source:J Environ Manage;177:365-72, 2016 Jul 15.
[Is] ISSN:1095-8630
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:The ability of mucilage from Dicerocaryum eriocarpum (DE) plant to act as biosorption medium in the removal of metals ions from aqueous solution was investigated. Functional groups present in the mucilage were identified using Fourier transform infrared spectroscopy (FTIR). Mucilage was modified with sodium and potassium chlorides. This was aimed at assessing the biosorption efficiency of modified mucilage: potassium mucilage (PCE) and sodium mucilage (SCE) and comparing it with non-modified deionised water mucilage (DCE) in the uptake of metal ions. FTIR results showed that the functional groups providing the active sites in PCE and SCE and DCE include: carboxyl, hydroxyl and carbonyl groups. The chloride used in the modification of the mucilage did not introduce new functional groups but increased the intensity of the already existing functional groups in the mucilage. Results from biosorption experiment showed that DE mucilage displays good binding affinity with metals ions [Zn(II), Cd(II) Ni(II), Cr(III) and Fe(II)] in the aqueous solution. Increase in the aqueous solution pH, metal ions initial concentration and mucilage concentration increased the biosorption efficiency of DE mucilage. The maximum contact time varied with each species of metal ions. Optimum pH for [Zn(II), Cd(II) Ni(II) and Fe(II)] occurred at pH 4 and pH 6 for Cr(III). Kinetic models result fitted well to pseudo-second-order with a coefficient values of R(2) = 1 for Cd(II), Ni(II), Cr(III), Fe(II) and R(2) = 0.9974 for Zn(II). Biosorption isotherms conforms best with Freundlich model for all the metal ions with correlation factors of 0.9994, 0.9987, 0.9554, 0.9621 and 0.937 for Zn(II), Ni(II), Fe(II), Cr(III) and Cd(II), respectively. Biosorption capacity of DE mucilage was 0.010, 2.387, 4.902, 0688 and 0.125 for Zn(II), Cr(III), Fe(II), Cd(II) and Ni(II) respectively. The modified mucilage was found to be highly efficient in the removal of metal ions than the unmodified mucilage.
[Mh] Termos MeSH primário: Metais Pesados/isolamento & purificação
Pedaliaceae/química
Poluentes Químicos da Água/isolamento & purificação
Purificação da Água/métodos
[Mh] Termos MeSH secundário: Adsorção
Concentração de Íons de Hidrogênio
Cinética
Potássio/química
Sódio/química
Espectroscopia de Infravermelho com Transformada de Fourier
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Metals, Heavy); 0 (Water Pollutants, Chemical); 9NEZ333N27 (Sodium); RWP5GA015D (Potassium)
[Em] Mês de entrada:1703
[Cu] Atualização por classe:170817
[Lr] Data última revisão:
170817
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160507
[St] Status:MEDLINE


  4 / 27 MEDLINE  
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[PMID]:26657496
[Au] Autor:Masondo NA; Finnie JF; Van Staden J
[Ad] Endereço:Research Centre for Plant Growth and Development, School of Life Sciences, University of KwaZulu-Natal, Pietermaritzburg Campus, P/Bag X01, Scottsville 3209, South Africa.
[Ti] Título:Nutritional and pharmacological potential of the genus Ceratotheca--An underutilized leafy vegetable of Africa.
[So] Source:J Ethnopharmacol;178:209-21, 2016 Feb 03.
[Is] ISSN:1872-7573
[Cp] País de publicação:Ireland
[La] Idioma:eng
[Ab] Resumo:ETHNOPHARMACOLOGICAL RELEVANCE: Ceratotheca (Pedaliaceae) is an endemic African genus comprising of five species. The genus is commonly used as a leafy vegetable with medicinal properties. AIM OF THE REVIEW: The review aims to highlight the unexplored nutritional and pharmacological potential of African indigenous leafy vegetables Ceratotheca sesamoides and triloba, in order to conserve and domesticate these species. METHODS: The information was obtained from various search engines such as Scopus, Google Scholar and Web of Science as well as Ethnobotanical books. RESULTS: Ceratotheca sesamoides and triloba have good nutritional potential. The species are high in energy levels, fat content, proteins and carbohydrate values. The species have also been reported to have good antibacterial, antidiarrhoeal, antidiabetic, antiplasmodial and antiviral properties. These species have slight toxicity and cytotoxic activity when extracted at high concentrations but no mutagenic activity was detected. CONCLUSIONS: To date, few studies have documented the usage (nutrition and pharmacology) of Ceratotheca sesamoides and triloba. More studies investigating the nutritional content as well as methods of its improvement are necessary if the plant is to be included as a domesticated vegetable crop. Safety and toxicity analysis of this leafy vegetable need to be extensively studied as the plants are consumed in high quantities.
[Mh] Termos MeSH primário: Pedaliaceae/química
Extratos Vegetais/farmacologia
Folhas de Planta/química
Verduras/química
[Mh] Termos MeSH secundário: África
Animais
Seres Humanos
Medicina Tradicional/métodos
Extratos Vegetais/química
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T; REVIEW
[Nm] Nome de substância:
0 (Plant Extracts)
[Em] Mês de entrada:1610
[Cu] Atualização por classe:161230
[Lr] Data última revisão:
161230
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:151215
[St] Status:MEDLINE


  5 / 27 MEDLINE  
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[PMID]:24146508
[Au] Autor:Patel MK; Mandavia DR; Patel TK; Barvaliya MJ; Tripathi CB
[Ad] Endereço:Department of Pharmacology, Government Medical College, Bhavnagar - 364001, Gujarat, India.
[Ti] Título:Evaluation of anti-inflammatory, analgesic, and antipyretic effects of ethanolic extract of Pedalium murex Linn. fruits.
[So] Source:Afr J Tradit Complement Altern Med;10(4):94-100, 2013.
[Is] ISSN:2505-0044
[Cp] País de publicação:Nigeria
[La] Idioma:eng
[Ab] Resumo:This study investigated the possible anti-inflammatory, analgesic, and antipyretic effects of ethanolic extract of Pedalium murex Linn. fruits in selected experimental animal models. Anti-inflammatory activity of Pedalium murex Linn., with doses of 200 mg/kg and 400 mg/kg, p.o., was evaluated by Lambda-carrageenan induced paw oedema in Wistar albino rats; analgesic activity with doses of 280 mg/kg and 560 mg/kg, p.o., was evaluated by hot plate method and acetic acid induced writhing method in Swiss albino mice; and antipyretic activity with doses of 110 mg/kg and 220 mg/kg, p.o., was evaluated in New Zealand white rabbits by injecting gram -ve lipopolysaccharide obtained from E. coli. Results were analysed by one way ANOVA followed by Dunnet's multiple comparison test. Pedalium murex Linn. showed significant anti-inflammatory activity from 15 min to 180 min as compared to vehicle treated animals. It was comparable to diclofenac sodium at 180 min. The extract did not prolong the reaction time on hot plate method but significantly reduced the number of writhing after acetic acid administration. Also the extract did not show any antipyretic activity on lipopolysaccharide induced pyrexia. It is therefore concluded that the ethanolic extract of Pedalium murex Linn. fruits has an anti-inflammatory and peripheral analgesic effects.
[Mh] Termos MeSH primário: Analgésicos/uso terapêutico
Anti-Inflamatórios/uso terapêutico
Antipiréticos/farmacologia
Inflamação/tratamento farmacológico
Dor/tratamento farmacológico
Pedaliaceae
Fitoterapia
[Mh] Termos MeSH secundário: Ácido Acético
Analgésicos/farmacologia
Análise de Variância
Animais
Anti-Inflamatórios/farmacologia
Carragenina
Edema/induzido quimicamente
Edema/tratamento farmacológico
Escherichia coli
Febre/induzido quimicamente
Frutas
Temperatura Alta
Inflamação/induzido quimicamente
Lipopolissacarídeos
Camundongos
Camundongos Endogâmicos
Dor/etiologia
Extratos Vegetais/farmacologia
Extratos Vegetais/uso terapêutico
Coelhos
Ratos
Ratos Wistar
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Analgesics); 0 (Anti-Inflammatory Agents); 0 (Antipyretics); 0 (Lipopolysaccharides); 0 (Plant Extracts); 9000-07-1 (Carrageenan); Q40Q9N063P (Acetic Acid)
[Em] Mês de entrada:1405
[Cu] Atualização por classe:170220
[Lr] Data última revisão:
170220
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:131023
[St] Status:MEDLINE


  6 / 27 MEDLINE  
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[PMID]:24078501
[Au] Autor:Mandavia DR; Patel MK; Patel JC; Anovadiya AP; Baxi SN; Tripathi CR
[Ad] Endereço:Department of Pharmacology, Government Medical College and Sir Takhtasinhji General Hospital, Bhavnagar-364001 (Gujarat), India.. cbrtripathi@yahoo.co.in.
[Ti] Título:Anti-urolithiatic effect of ethanolic extract of Pedalium murex linn. fruits on ethylene glycol-induced renal calculi.
[So] Source:Urol J;10(3):946-52, 2013 Sep 26.
[Is] ISSN:1735-546X
[Cp] País de publicação:Iran
[La] Idioma:eng
[Ab] Resumo:PURPOSE: To evaluate effect of ethanolic extract of Pedalium murex Linn. fruits on experimental model of calcium oxalate nephrolithiasis. MATERIALS AND METHODS: Thirty-six male Wistar albino rats were randomly divided in 6 groups.Normal controls received distilled water for 28 days. Other five groups received ethylene glycol(1% v/v) in distilled water for 28 days. Pedalium murex ethanolic extract was given 200 mg/kg and 400 mg/kg orally in distilled water for 28 days in prophylactic groups (III and IV) and from 15th to 28th days in treatment groups (V and VI). The urea, creatinine, random blood sugar, aspartate aminotransferase, alanine aminotransferase, alkaline phosphatase, bilirubin and calcium were measured on 28th day. 24 hr urinary oxalate and volume were measured on day 0 and 28. On day 28, kidneys were removed, weighed and subjected to histopathological examination. Calcium oxalate crystallization was evaluated by renal histopathology and in-vitro method of mineralization.All parameters were analyzed by Kruskal-Wallis or one-way ANOVA with post-hoc test. RESULTS: Pedalium murex showed significant improvement in renal function and kidney weight inprophylactic groups as compared to ethylene glycol controls. It did not show any effect on urinary oxalate, urine volume and any other serological parameters. Calcium oxalate crystallization was significantly reduced in all the Pedalium murex treated groups (P < .05). Calcium oxalate and phosphate mineralization were also inhibited by 33% and 57%. CONCLUSION: Ethanolic extract of Pedalium murex fruits possess significant activity for prevention of renal calculi.
[Mh] Termos MeSH primário: Cálculos Renais/prevenção & controle
Pedaliaceae
Fitoterapia
Extratos Vegetais/uso terapêutico
[Mh] Termos MeSH secundário: Animais
Etanol
Etilenoglicol/farmacologia
Frutas
Cálculos Renais/induzido quimicamente
Masculino
Ratos
Ratos Wistar
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Plant Extracts); 3K9958V90M (Ethanol); FC72KVT52F (Ethylene Glycol)
[Em] Mês de entrada:1405
[Cu] Atualização por classe:130930
[Lr] Data última revisão:
130930
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:131001
[St] Status:MEDLINE


  7 / 27 MEDLINE  
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[PMID]:23642455
[Au] Autor:Georgiev MI; Ivanovska N; Alipieva K; Dimitrova P; Verpoorte R
[Ad] Endereço:Laboratory of Applied Biotechnologies, Institute of Microbiology, Bulgarian Academy of Sciences, Plovdiv, Bulgaria. milengeorgiev@gbg.bg
[Ti] Título:Harpagoside: from Kalahari Desert to pharmacy shelf.
[So] Source:Phytochemistry;92:8-15, 2013 Aug.
[Is] ISSN:1873-3700
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Harpagoside is an iridoid glycoside that was first isolated from Harpagophytum procumbens (devil's claw, Pedaliaceae), a medicinal plant in which it is the major constituent of the iridoid pool. Both the pure compound and devil's claw extracts have potent anti-rheumatic, anti-inflammatory and analgesic effects. According to the European Pharmacopoeia commercial devil's claw products should contain at least 1.2% harpagoside. However, the compound has also been isolated from several other plant species and in vitro plant culture systems. Recent advances in knowledge of harpagoside distribution, biosynthesis/accumulation and pharmacology are summarized in this review. We also discuss the possible synergism and/or antagonism between major constituents in harpagoside-containing phytopharmaceutical products. Finally, future perspectives for its potential application are highlighted.
[Mh] Termos MeSH primário: Glicosídeos/isolamento & purificação
Pedaliaceae/química
Preparações Farmacêuticas/isolamento & purificação
Piranos/isolamento & purificação
[Mh] Termos MeSH secundário: Glicosídeos/química
Preparações Farmacêuticas/química
Piranos/química
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Glycosides); 0 (Pharmaceutical Preparations); 0 (Pyrans); 8KGS1DC5ZU (harpagoside)
[Em] Mês de entrada:1402
[Cu] Atualização por classe:161125
[Lr] Data última revisão:
161125
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:130507
[St] Status:MEDLINE


  8 / 27 MEDLINE  
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[PMID]:23608325
[Au] Autor:Lodhi S; Singhai AK
[Ad] Endereço:Department of Pharmaceutical Sciences, Dr. H. S. Gour University, Sagar (M.P.), India.
[Ti] Título:Wound healing effect of flavonoid rich fraction and luteolin isolated from Martynia annua Linn. on streptozotocin induced diabetic rats.
[So] Source:Asian Pac J Trop Med;6(4):253-9, 2013 Apr 13.
[Is] ISSN:2352-4146
[Cp] País de publicação:China
[La] Idioma:eng
[Ab] Resumo:OBJECTIVE: To evaluate wound healing potential of flavonoid fractions of Martynia annua (M. annua) Linn. leaves in diabetic rats on the basis of folkloric information and preliminary study. METHODS: The flavonoid compound luteolin and apigenin were isolated from dried leaves of plant by column chromatography. The two concentrations (0.2% and 0.5% w/w) of luteolin and flavonoid fraction were selected for topically applied as ointment on diabetic wound. The Povidone Iodine Ointment USP was used as a reference. On 18th days, protein content, hydroxyproline and antioxidants (SOD, CAT and GSH) level in granuloma tissues were determined. RESULTS: The results showed that, percent wound contraction were observed significantly (P<0.01) greater in MAF fraction and 0.5% w/w of luteolin treatment groups. Presence of matured collagen fibres and fibroblasts with better angiogenesis were observed in histopathological studies. CONCLUSIONS: In conclusion, our findings suggest that flavonoid fraction (MAF) and luteolin (0.5% w/w) may have potential benefit in enhancing wound healing in diabetic condition, possibly due to free-radical scavenging activity of plant.
[Mh] Termos MeSH primário: Flavonoides/farmacologia
Pedaliaceae
Fitoterapia/métodos
Extratos Vegetais/farmacologia
Cicatrização/efeitos dos fármacos
[Mh] Termos MeSH secundário: Administração Cutânea
Animais
Antioxidantes/metabolismo
Diabetes Mellitus Experimental/patologia
Diabetes Mellitus Experimental/fisiopatologia
Relação Dose-Resposta a Droga
Erupção por Droga/etiologia
Feminino
Fibroblastos/efeitos dos fármacos
Flavonoides/administração & dosagem
Flavonoides/efeitos adversos
Depuradores de Radicais Livres/farmacologia
Hidroxiprolina/metabolismo
Luteolina/administração & dosagem
Luteolina/efeitos adversos
Luteolina/farmacologia
Masculino
Pomadas
Extratos Vegetais/administração & dosagem
Folhas de Planta
Proteínas/metabolismo
Ratos
Ratos Wistar
Pele/química
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Antioxidants); 0 (Flavonoids); 0 (Free Radical Scavengers); 0 (Ointments); 0 (Plant Extracts); 0 (Proteins); KUX1ZNC9J2 (Luteolin); RMB44WO89X (Hydroxyproline)
[Em] Mês de entrada:1310
[Cu] Atualização por classe:160519
[Lr] Data última revisão:
160519
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:130424
[St] Status:MEDLINE


  9 / 27 MEDLINE  
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[PMID]:23569975
[Au] Autor:Rajashekar V; Rao EU; P S
[Ad] Endereço:Department of Pharmaceutical Microbiology, Vikas College of Pharmacy, Jangaon-506167, Warangal District (A.P), India.
[Ti] Título:Biological activities and medicinal properties of Gokhru (Pedalium murex L.).
[So] Source:Asian Pac J Trop Biomed;2(7):581-5, 2012 Jul.
[Is] ISSN:2221-1691
[Cp] País de publicação:China
[La] Idioma:eng
[Ab] Resumo:Bada Gokhru (Pedalium murex L.) is perhaps the most useful traditional medicinal plant in India. Each part of the neem tree has some medicinal property and is thus commercially exploitable. During the last five decades, apart from the chemistry of the Pedalium murex compounds, considerable progress has been achieved regarding the biological activity and medicinal applications of this plant. It is now considered as a valuable source of unique natural products for development of medicines against various diseases and also for the development of industrial products. This review gives a bird's eye view mainly on the biological activities of some of this compounds isolated, pharmacological actions of the extracts, clinical studies and plausible medicinal applications of gokharu along with their safety evaluation.
[Mh] Termos MeSH primário: Anti-Infecciosos/farmacologia
Antioxidantes/farmacologia
Produtos Biológicos/farmacologia
Pedaliaceae/química
Plantas Medicinais/química
[Mh] Termos MeSH secundário: Anti-Infecciosos/isolamento & purificação
Antioxidantes/isolamento & purificação
Produtos Biológicos/isolamento & purificação
Seres Humanos
Índia
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Nm] Nome de substância:
0 (Anti-Infective Agents); 0 (Antioxidants); 0 (Biological Products)
[Em] Mês de entrada:1503
[Cu] Atualização por classe:150427
[Lr] Data última revisão:
150427
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:130410
[St] Status:MEDLINE
[do] DOI:10.1016/S2221-1691(12)60101-4


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[PMID]:22899621
[Au] Autor:Ohkawa A; Sakai T; Ohyama K; Fujimoto Y
[Ad] Endereço:Department of Chemistry and Materials Science, Tokyo Institute of Technology, Meguro, Tokyo 152-8551, Japan.
[Ti] Título:Malonylated glycerolipids from the glandular trichome exudate of Ceratotheca triloba.
[So] Source:Chem Biodivers;9(8):1611-7, 2012 Aug.
[Is] ISSN:1612-1880
[Cp] País de publicação:Switzerland
[La] Idioma:eng
[Ab] Resumo:Chemical investigation of the glandular trichome exudate from Ceratotheca triloba (Pedaliaceae) led to the identification of nine 1-O-acetyl-2-O-[(R)-3-acetyloxy-fatty acyl]-3-O-malonylglycerols. Among these, 1-O-acetyl-2-O-[(R)-3-acetyloxyicosanoyl]-3-O-malonylglycerol (7) was the most abundant constituent (41%), followed by 1-O-acetyl-2-O-[(R)-(3-acetyloxyoctadecanoyl)-3-O-malonylglycerol (2; 21%). Compounds having iso- and anteiso-type structures in the 3-acetyloxy-fatty acyl groups in the fatty acyl moiety were also characterized as minor constituents. This is the first report of the isolation of malonylated glycerolipids as natural products.
[Mh] Termos MeSH primário: Ácidos Graxos/química
Glicerol/análogos & derivados
Malonatos/química
Pedaliaceae/química
Extratos Vegetais/química
[Mh] Termos MeSH secundário: Ácidos Graxos/isolamento & purificação
Glicerol/isolamento & purificação
Malonatos/isolamento & purificação
Extratos Vegetais/isolamento & purificação
Estereoisomerismo
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Fatty Acids); 0 (Malonates); 0 (Plant Extracts); PDC6A3C0OX (Glycerol)
[Em] Mês de entrada:1301
[Cu] Atualização por classe:131121
[Lr] Data última revisão:
131121
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:120818
[St] Status:MEDLINE
[do] DOI:10.1002/cbdv.201200097



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