Base de dados : MEDLINE
Pesquisa : B01.650.940.800.575.912.250.583.700.700 [Categoria DeCS]
Referências encontradas : 712 [refinar]
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[PMID]:28934712
[Au] Autor:Stuchlíková LR; Skálová L; Szotáková B; Syslová E; Vokrál I; Vanek T; Podlipná R
[Ad] Endereço:Department of Biochemical Sciences, Faculty of Pharmacy in Hradec Králové, Charles University, Heyrovského 1203, 500 05 Hradec Králové, Czech Republic. Electronic address: lucie.raisova@faf.cuni.cz.
[Ti] Título:Biotransformation of flubendazole and fenbendazole and their effects in the ribwort plantain (Plantago lanceolata).
[So] Source:Ecotoxicol Environ Saf;147:681-687, 2018 Jan.
[Is] ISSN:1090-2414
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:Although veterinary anthelmintics represent an important source of environmental pollution, the fate of anthelmintics and their effects in plants has not yet been studied sufficiently. The aim of our work was to identify metabolic pathways of the two benzimidazole anthelmintics fenbendazole (FBZ) and flubendazole (FLU) in the ribwort plantain (Plantago lanceolata L.). Plants cultivated as in vitro regenerants were used for this purpose. The effects of anthelmintics and their biotransformation products on plant oxidative stress parameters were also studied. The obtained results showed that the enzymatic system of the ribwort plantain was able to uptake FLU and FBZ, translocate them in leaves and transform them into several metabolites, particularly glycosides. Overall, 12 FLU and 22 FBZ metabolites were identified in the root, leaf base and leaf top of the plant. Concerning the effects of FLU and FBZ, both anthelmintics in the ribwort plantain cells caused significant increase of proline concentration (up to twice), a well-known stress marker, and significant decrease of superoxide dismutase activity (by 50%). In addition, the activities of four other antioxidant enzymes were significantly changed after either FLU or FBZ exposition. This could indicate a certain risk of oxidative damage in plants influenced by anthelmintics, particularly when they are under other stress conditions.
[Mh] Termos MeSH primário: Anti-Helmínticos/toxicidade
Fenbendazol/toxicidade
Mebendazol/análogos & derivados
Plantago/efeitos dos fármacos
Drogas Veterinárias/toxicidade
[Mh] Termos MeSH secundário: Animais
Anti-Helmínticos/metabolismo
Biotransformação
Fenbendazol/metabolismo
Mebendazol/metabolismo
Mebendazol/toxicidade
Redes e Vias Metabólicas/efeitos dos fármacos
Estresse Oxidativo/efeitos dos fármacos
Plantago/enzimologia
Plantago/crescimento & desenvolvimento
Drogas Veterinárias/metabolismo
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Anthelmintics); 0 (Veterinary Drugs); 621BVT9M36 (Fenbendazole); 81G6I5V05I (Mebendazole); R8M46911LR (flubendazole)
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180309
[Lr] Data última revisão:
180309
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170922
[St] Status:MEDLINE


  2 / 712 MEDLINE  
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[PMID]:29210242
[Au] Autor:Köhl L; Oehl F; van der Heijden MGA
[Ti] Título:Agricultural practices indirectly influence plant productivity and ecosystem services through effects on soil biota.
[So] Source:Ecol Appl;24(7):1842-53, 2014.
[Is] ISSN:1051-0761
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:It is well established that agricultural practices alter the composition and diversity of soil microbial communities. However, the impact of changing soil microbial communities on the functioning of the agroecosystems is still poorly understood. Earlier work showed that soil tillage drastically altered microbial community composition. Here we tested, using an experimental grassland (Lolium, Trifolium, Plantago) as a model system, whether soil microbial communities from conventionally tilled (CT) and non-tilled (NT) soils have different influences on plant productivity and nutrient acquisition. We specifically focus on arbuscular mycorrhizal fungi (AMF), as they are a group of beneficial soil fungi that can promote plant productivity and ecosystem functioning and are also strongly affected by tillage management. Soil microbial communities from CT and NT soils varied greatly in their effects on the grassland communities. Communities from CT soil increased overall biomass production more than soil communities from NT soil. This effect was mainly due to a significant growth promotion of Trifolium by CT microorganisms. In contrast to CT soil inoculum, NT soil inoculum increased plant phosphorus concentration and total plant P content, demonstrating that the soil microbial communities from NT fields enhance P uptake. Differences in AM fungal community composition resulting, for instance, in twofold greater hyphal length in NT soil communities when compared to CT, are the most likely explanation for the different plant responses to CT and NT soil inocula. A range of field studies have shown that plant P uptake increases when farmers change to conservation tillage or direct seeding. Our results indicate that this enhanced P uptake results from enhanced hyphal length and an altered AM fungal community. Our results further demonstrate that agricultural management practices indirectly influence ecosystem services and plant community structure through effects on soil biota.
[Mh] Termos MeSH primário: Agricultura
Lolium/fisiologia
Micorrizas/fisiologia
Plantago/fisiologia
Microbiologia do Solo
Trifolium/fisiologia
[Mh] Termos MeSH secundário: Animais
Asteraceae/microbiologia
Asteraceae/fisiologia
Biomassa
Ecossistema
Lolium/microbiologia
Raízes de Plantas/crescimento & desenvolvimento
Raízes de Plantas/microbiologia
Plantago/microbiologia
Trifolium/microbiologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180108
[Lr] Data última revisão:
180108
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171207
[St] Status:MEDLINE


  3 / 712 MEDLINE  
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[PMID]:28592281
[Au] Autor:Díez R; García JJ; Diez MJ; Sierra M; Sahagun AM; Fernández N
[Ad] Endereço:Pharmacology, Institute of Biomedicine (IBIOMED), University of León, 24071, León, Spain. rdielz@unileon.es.
[Ti] Título:Influence of Plantago ovata husk (dietary fiber) on the bioavailability and other pharmacokinetic parameters of metformin in diabetic rabbits.
[So] Source:BMC Complement Altern Med;17(1):298, 2017 Jun 07.
[Is] ISSN:1472-6882
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Metformin is an oral hypoglycemic agent frequently used in patients with type 2 diabetes. In this study, we have investigated the influence of the dietary fiber Plantago ovata husk on the pharmacokinetics of this drug when included in the diet, as well as when administered at the same time as metformin. METHODS: Six groups of 6 rabbits were used. Groups 1 to 3 were fed with standard chow and groups 4 to 6 with chow supplemented with fiber (3.5 mg/kg/day). Groups 1 and 4 received metformin intravenously (30 mg/kg). Groups 2 and 5 received metfomin orally (30 mg/kg), and number 3 and 6 were treated orally with metformin (30 mg/kg) and fiber (300 mg/kg). RESULTS: The changes caused by the inclusion of fiber in the feeding were more important in groups that received oral metformin. In this way, metformin oral bioavailability showed an increase of 34.42% when rabbits were fed with supplemented chow. CONCLUSIONS: Plantago ovata husk increased the amount of absorbed metformin when included in the diet (significant increase in AUC), and delayed its absorption when administered at the same time (significant increase in t ).
[Mh] Termos MeSH primário: Diabetes Mellitus Tipo 2/tratamento farmacológico
Fibras na Dieta/administração & dosagem
Hipoglicemiantes/farmacocinética
Metformina/farmacocinética
Extratos Vegetais/administração & dosagem
Plantago/química
[Mh] Termos MeSH secundário: Animais
Disponibilidade Biológica
Seres Humanos
Hipoglicemiantes/administração & dosagem
Masculino
Metformina/administração & dosagem
Coelhos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Dietary Fiber); 0 (Hypoglycemic Agents); 0 (Plant Extracts); 9100L32L2N (Metformin)
[Em] Mês de entrada:1708
[Cu] Atualização por classe:171116
[Lr] Data última revisão:
171116
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170609
[St] Status:MEDLINE
[do] DOI:10.1186/s12906-017-1809-x


  4 / 712 MEDLINE  
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[PMID]:28570890
[Au] Autor:Nadgórska-Socha A; Kandziora-Ciupa M; Trzesicki M; Barczyk G
[Ad] Endereço:University of Silesia, Department of Ecology, Bankowa 9, PL 40-007, Katowice, Poland. Electronic address: aleksandra.nadgorska-socha@us.edu.pl.
[Ti] Título:Air pollution tolerance index and heavy metal bioaccumulation in selected plant species from urban biotopes.
[So] Source:Chemosphere;183:471-482, 2017 Sep.
[Is] ISSN:1879-1298
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:This research was carried out on plants Taraxacum officinale, Plantago lanceolata, Betula pendula and Robinia pseudoacacia growing in urban biotopes with different levels of heavy metal contamination in the city of Dabrowa Górnicza (southern Poland). Based on the pollution index, the highest heavy metal contamination was determined in the site 4 (connected with industry emitters) and 6 (high traffic). The metal accumulation index (MAI) values ranged within the biotopes in Dabrowa Górnicza between 7.3 and 20.6 for R. pseudoacacia, 4.71-23.1 for P. lanceolata, 4.68-28.1 for T. officinale and 10.5-27.2 for B. pendula. Increasing tendency in proline content in biotopes connected with high traffic was found in the leaves of investigated plants (except R. pseudoacacia). Similar tendency was observed for ascorbic acid content in the foliage of the plants as well as in T. officinalle in stands connected industrial emission. Non-protein thiols content increased especially in the leaves of R. pseudoacacia in biotopes with high traffic emissions as well as in T. officinale in stands connected with industry. The mean values of APTI (Air Pollution Tolerance Index) within the city of Dabrowa Górnicza for investigated plants were found in the following ascending order P. lanceolata < R. pseudoacacia < B. pendula < T. officinale. Among the investigated plants B. pendula and T. officinale may be postulated as appropriate plants in urban areas with considerable soil and air contamination, especially with heavy metals. The results indicate that species deemed tolerant according to APTI are suitable plants in barriers areas to combat atmospheric pollution.
[Mh] Termos MeSH primário: Poluentes Atmosféricos/análise
Monitoramento Ambiental/métodos
Metais Pesados/análise
Folhas de Planta/metabolismo
[Mh] Termos MeSH secundário: Poluentes Atmosféricos/metabolismo
Ácido Ascórbico/análise
Betula/química
Betula/metabolismo
Cidades
Metais Pesados/metabolismo
Modelos Biológicos
Folhas de Planta/química
Plantago/química
Plantago/metabolismo
Polônia
Robinia/química
Robinia/metabolismo
Estações do Ano
Poluentes do Solo/análise
Especificidade da Espécie
Taraxacum/química
Taraxacum/metabolismo
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Air Pollutants); 0 (Metals, Heavy); 0 (Soil Pollutants); PQ6CK8PD0R (Ascorbic Acid)
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170915
[Lr] Data última revisão:
170915
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170602
[St] Status:MEDLINE


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[PMID]:28420111
[Au] Autor:Kho MC; Park JH; Han BH; Tan R; Yoon JJ; Kim HY; Ahn YM; Lee YJ; Kang DG; Lee HS
[Ad] Endereço:Hanbang Body-fluid Research Center, Wonkwang University, 460 Iksandae-ro, Iksan, Jeonbuk 54538, Korea. shadowzetx@hanmail.net.
[Ti] Título:Plantago asiatica L. Ameliorates Puromycin Aminonucleoside-Induced Nephrotic Syndrome by Suppressing Inflammation and Apoptosis.
[So] Source:Nutrients;9(4), 2017 Apr 14.
[Is] ISSN:2072-6643
[Cp] País de publicação:Switzerland
[La] Idioma:eng
[Ab] Resumo:OBJECTIVE: Nephrotic syndrome, a kidney disease with a variety of causes, is mainly characterized by heavy proteinuria, hypoproteinemia, and ascites. This study was designed to evaluate the underlying mechanism of action of L. (PAL) in treating nephrotic syndrome induced by puromycin aminonucleoside. METHODS: PAL has been used in Asia as a traditional medicine and dietary health supplement. Sprague-Dawley (SD) rats were intravenously injected with puromycin aminonucleoside (75 mg/kg/day), then treated with either Losartan (30 mg/kg/day) or PAL (200 mg/kg/day) by oral gavage for seven days. RESULTS: PAL significantly decreased ascites, proteinuria level, and plasma lipid parameters. In addition, treatment with PAL attenuated histological damage and hypoalbuminemia. Treatment with PAL also restored podocin expression and reduced inflammation markers such as intracellular adhesion molecules (ICAM-1), monocyte chemotactic protein-1 (MCP-1), tumor necrosis factor alpha (TNF-α) and high-mobility group box-1 (HMGB1). Lower expression levels of the apoptosis markers Bax, caspase-3 and capase-9 were documented in SD rats receiving PAL. PAL also significantly decreased the phosphorylation levels of MAPKs such as ERK, JNK and p38. CONCLUSION: As a multifunctional agent, PAL has a renoprotective effect in nephrotic syndrome rat models. The anti-inflammatory and anti-apoptotic properties, along with reductions in hyperlipidemia and ascites, represent important therapeutic effects. These results indicate that is likely to be a promising agent in the treatment of nephrotic syndrome.
[Mh] Termos MeSH primário: Apoptose/efeitos dos fármacos
Inflamação/prevenção & controle
Rim/efeitos dos fármacos
Síndrome Nefrótica/tratamento farmacológico
Extratos Vegetais/farmacologia
Plantago
[Mh] Termos MeSH secundário: Animais
Ascite
Biomarcadores/sangue
Caspase 3/sangue
Caspase 9/sangue
Hipoalbuminemia/prevenção & controle
Inflamação/sangue
Peptídeos e Proteínas de Sinalização Intracelular/sangue
Rim/metabolismo
Rim/patologia
Lipídeos/sangue
Masculino
Proteínas de Membrana/sangue
Proteínas Quinases Ativadas por Mitógeno/sangue
Síndrome Nefrótica/induzido quimicamente
Síndrome Nefrótica/metabolismo
Síndrome Nefrótica/patologia
Fitoterapia
Extratos Vegetais/uso terapêutico
Puromicina Aminonucleosídeo
Ratos Sprague-Dawley
Proteína X Associada a bcl-2/sangue
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Biomarkers); 0 (Intracellular Signaling Peptides and Proteins); 0 (Lipids); 0 (Membrane Proteins); 0 (NPHS2 protein); 0 (Plant Extracts); 0 (bcl-2-Associated X Protein); 58-60-6 (Puromycin Aminonucleoside); EC 2.7.11.24 (Mitogen-Activated Protein Kinases); EC 3.4.22.- (Caspase 3); EC 3.4.22.- (Caspase 9)
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170919
[Lr] Data última revisão:
170919
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170420
[St] Status:MEDLINE


  6 / 712 MEDLINE  
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[PMID]:28372735
[Au] Autor:Su B; Zhou M; Xu H; Zhang X; Li Y; Su H; Xiang B
[Ad] Endereço:State Key Laboratory of Environmental Criteria and Risk Assessment, Chinese Research Academy of Environmental Sciences, Beijing 100012, China; State Key Laboratory of Vegetation and Environmental Change, Institute of Botany, Chinese Academy of Sciences, Beijing 100093, China. Electronic address: shu
[Ti] Título:Photosynthesis and biochemical responses to elevated O in Plantago major and Sonchus oleraceus growing in a lowland habitat of northern China.
[So] Source:J Environ Sci (China);53:113-121, 2017 Mar.
[Is] ISSN:1001-0742
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:A field experiment was carried out to compare the responses to ozone (O ) in two common herbaceous plant species, Plantago major L. and Sonchus oleraceus L., by building open-top growth chambers in situ to simulate O stress (+O , 85±5ppb, 9hr/day for 30days) in a lowland habitat in Inner Mongolia, Northern China. Responses to O of gas exchange, chlorophyll a fluorescence, leaf pigment content, antioxidant capability, soluble protein content, membrane lipid peroxidation and dark respiration (R ) were analyzed. Results showed that elevated O exposure significantly reduced the light-saturated net photosynthesis (P ), stomatal conductance (g ) and transpiration rate (E) in both species. Although non-significant interactive effect between species and O on P was analyzed, the reduction in P in S. oleraceus might be due primarily to the higher fraction of close PSII reaction centers and impaired activities of plant mesophyll cells as evidences by decreased maximum efficiency of PSII photochemistry after dark adapted state (F /F ) and unchanged intercellular CO concentration (C ). Besides, biochemical analysis showed that S. oleraceus had lower antioxidant ability compared to P. major. As a result, S. oleraceus was damaged to the larger extent in terms of lipid peroxidation and visible O injury, indicating that S. oleraceus was more sensitive to O than P. major. Our results indicated that wild herbaceous plant species growing in a lowland habitat in sandy grassland were sensitive to O stress and S. oleraceus can be considered as one of the bio-indicators for high O concentration in semi-arid grassland of northern China.
[Mh] Termos MeSH primário: Poluentes Atmosféricos/toxicidade
Ozônio/toxicidade
Fotossíntese/efeitos dos fármacos
Plantago/fisiologia
Sonchus/fisiologia
[Mh] Termos MeSH secundário: China
Ecossistema
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Air Pollutants); 66H7ZZK23N (Ozone)
[Em] Mês de entrada:1706
[Cu] Atualização por classe:170616
[Lr] Data última revisão:
170616
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170405
[St] Status:MEDLINE


  7 / 712 MEDLINE  
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[PMID]:28301809
[Au] Autor:Stuchlíková Raisová L; Podlipná R; Szotáková B; Syslová E; Skálová L
[Ad] Endereço:Department of Biochemical Sciences, Faculty of Pharmacy in Hradec Králové, Charles University in Prague, Heyrovského 1203, 500 05 Hradec Králové, Czech Republic. Electronic address: stuchli2@faf.cuni.cz.
[Ti] Título:Evaluation of drug uptake and deactivation in plant: Fate of albendazole in ribwort plantain (Plantago laceolata) cells and regenerants.
[So] Source:Ecotoxicol Environ Saf;141:37-42, 2017 Jul.
[Is] ISSN:1090-2414
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:Albendazole (ABZ) is a benzimidazole anthelmintic widely used especially in veterinary medicine. Along with other drugs, anthelmintics have become one of a new class of micro-pollutants that disturb the environment but the information about their fate in plants remains limited. The present study was designed to test the uptake and biotransformation of ABZ in the ribwort plantain (Plantago lancelota), a common meadow plant, which can come into contact with this anthelmintic through the excrements of treated animals in pastures. Two model systems were used and compared: cell suspensions and whole plant regenerants. In addition, time-dependent changes in occurrence of ABZ and its metabolites in roots, basal parts of the leaves and tops of the leaves were followed up. Ultrahigh-performance liquid chromatography coupled with high mass accuracy tandem mass spectrometry (UHPLC-MS/MS) led to the identification of 18 metabolites of ABZ formed in the ribwort. In both model systems, the same types of ABZ biotransformation reactions were found, but the spectrum and abundance of the ABZ metabolites detected in cell suspensions and regenerants differed significantly. Cell suspensions seem to be suitable only for qualitative estimations of drug biotransformation reactions while regenerants were shown to represent an adequate model for the qualitative as well as quantitative evaluation of drug uptake and metabolism in plants.
[Mh] Termos MeSH primário: Albendazol/análise
Anti-Helmínticos/análise
Plantago/metabolismo
Poluentes do Solo/análise
[Mh] Termos MeSH secundário: Albendazol/metabolismo
Animais
Anti-Helmínticos/metabolismo
Biodegradação Ambiental
Biotransformação
Cromatografia Líquida
Plantago/crescimento & desenvolvimento
Poluentes do Solo/metabolismo
Espectrometria de Massas em Tandem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Anthelmintics); 0 (Soil Pollutants); F4216019LN (Albendazole)
[Em] Mês de entrada:1707
[Cu] Atualização por classe:170724
[Lr] Data última revisão:
170724
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170317
[St] Status:MEDLINE


  8 / 712 MEDLINE  
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[PMID]:28283818
[Au] Autor:Susi H; Laine AL; Filloux D; Kraberger S; Farkas K; Bernardo P; Frilander MJ; Martin DP; Varsani A; Roumagnac P
[Ad] Endereço:Department of Biosciences, Metapopulation Research Centre, University of Helsinki, P.O. Box 65, 00014, Helsinki, Finland.
[Ti] Título:Genome sequences of a capulavirus infecting Plantago lanceolata in the Åland archipelago of Finland.
[So] Source:Arch Virol;162(7):2041-2045, 2017 Jul.
[Is] ISSN:1432-8798
[Cp] País de publicação:Austria
[La] Idioma:eng
[Ab] Resumo:The discovery and full-genome sequences of two isolates of a fourth capulavirus species are reported. The viruses were discovered during a viral metagenomics survey of uncultivated Plantago lanceolata plants in the Åland archipelago of south western Finland. The newly discovered viruses apparently produce no symptoms in P. lanceolata. They have a genome organization that is very similar to that of the three known capulavirus species and additionally share between 62.9 and 67.1% genome-wide sequence identity with the isolates of these species. It is therefore proposed that these viruses be assigned to a new capulavirus species named "Plantago lanceolata latent virus".
[Mh] Termos MeSH primário: Geminiviridae/classificação
Doenças das Plantas/virologia
Plantago/virologia
[Mh] Termos MeSH secundário: Finlândia
Geminiviridae/genética
Geminiviridae/isolamento & purificação
Metagenômica
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170802
[Lr] Data última revisão:
170802
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170312
[St] Status:MEDLINE
[do] DOI:10.1007/s00705-017-3298-0


  9 / 712 MEDLINE  
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[PMID]:28159616
[Au] Autor:Tomczak VV; Müller C
[Ad] Endereço:Department of Chemical Ecology, Bielefeld University, Bielefeld, Germany.
[Ti] Título:Influence of arbuscular mycorrhizal stage and plant age on the performance of a generalist aphid.
[So] Source:J Insect Physiol;98:258-266, 2017 Apr.
[Is] ISSN:1879-1611
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Host plant quality for herbivores is modulated by different factors including symbiosis with soil organisms, such as arbuscular mycorrhiza (AM), as well as plant age. However, the role of the developmental stage of the AM in such plant-microbe-herbivore interactions has been neglected. To investigate the effects of AM stage and plant age on aphid performance, individuals of the generalist Myzus persicae were reared on leaves of non-mycorrhized (NM) or mycorrhized (AM) Plantago lanceolata plants at two time points, on young plants (with a minor established AM) and on older plants (with a well-established AM), respectively. Various performance traits were measured in the first aphid generation. Additionally, the body mass of the offspring was recorded to determine effects of previous infestation on the next generation. At the end of the herbivore experiments, plant carbon (C), nitrogen (N) and phosphorus (P) as well as leaf mass per area (LMA) were analyzed as measures of plant quality. Developmental performance traits of the aphids were either affected by AM and time point (nymph body mass at day 6) or by the interaction of both (relative growth rate). However, body mass at day 10 and reproductive performance traits were lower on older plants, independent of AM treatment. In line with these results, host plant quality changed little due to AM but strongly with age, with decreases in leaf N and P, but increases in C and LMA. Furthermore, nymphs gained a higher body mass when feeding on previously infested plants compared to their parents that started to feed on non-infested hosts, likely due to an aphid-induced modification in host traits. In summary, our results indicate that effects of both the developmental stage of AM and the plant age on aphid performance change throughout aphid development and between generations, attributable to shifts in plant quality.
[Mh] Termos MeSH primário: Afídeos/fisiologia
Herbivoria
Micorrizas/fisiologia
Plantago/microbiologia
[Mh] Termos MeSH secundário: Animais
Afídeos/crescimento & desenvolvimento
Ninfa/crescimento & desenvolvimento
Ninfa/fisiologia
Folhas de Planta/química
Folhas de Planta/microbiologia
Plantago/química
Reprodução
Simbiose
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1707
[Cu] Atualização por classe:170714
[Lr] Data última revisão:
170714
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170205
[St] Status:MEDLINE


  10 / 712 MEDLINE  
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[PMID]:28126622
[Au] Autor:Moya R; Rubio V; Beitia JM; Carnés J; López-Matas MA
[Ad] Endereço:R&D Department, Laboratorios LETI, S.L.U., C/del Sol 5, Tres Cantos, 28760, Madrid, Spain.
[Ti] Título:Purification and immunochemical characterization of Pla l 2, the profilin from Plantago lanceolata.
[So] Source:Mol Immunol;83:100-106, 2017 Mar.
[Is] ISSN:1872-9142
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Profilins are small actin-binding proteins found in eukaryotes and involved in cell development, cytokinesis, membrane trafficking, and cell motility. From an allergenic point of view, profilins are panallergens usually involved in allergic polysensitization, although they are generally recognized as minor allergens. The objectives of this study were to identify and characterize the profilin from Plantago lanceolata pollen and to investigate the cross-reactivity between profilins from different pollen allergenic sources. Profilins from P. lancelolata (Pla l 2) and palm tree pollen (Pho d 2) were purified by affinity chromatography, deeply characterized and identified by mass spectrometry. Pla l 2 allergenicity was confirmed by immunoblot with serum samples from a patient population sensitized to profilin. Immunoblot inhibition was performed to study IgG reactivity between different pollen profilins. IgE cross-reactivity was demonstrated by ImmunoCAP inhibition. Pla l 2 is the second P. lanceolata allergen included in the IUIS Allergen Nomenclature database. Four peptides from purified Pla l 2 were identified with percentages of homology with other pollen profilins between 73 and 86%. Eighty-six percent (21/24) of the patient population recognized Pla l 2. The allergenic relatedness between Pla l 2, Pho d 2 and six pollen profilins was confirmed, and IgE cross-reactivity of Pla l 2 with rBet v 2 and rPhl p 12 was demonstrated. Pla l 2 is the profilin from P. lanceolata. The demonstrated allergenicity of this protein and its cross-reactivity with other pollen profilins support its use in profilin diagnostic assays.
[Mh] Termos MeSH primário: Alérgenos/imunologia
Glicoproteínas/imunologia
Proteínas de Plantas/imunologia
Plantago/imunologia
Profilinas/imunologia
[Mh] Termos MeSH secundário: Adolescente
Adulto
Alérgenos/isolamento & purificação
Animais
Antígenos de Plantas/imunologia
Antígenos de Plantas/isolamento & purificação
Reações Cruzadas
Feminino
Glicoproteínas/isolamento & purificação
Seres Humanos
Immunoblotting
Masculino
Pólen/imunologia
Profilinas/isolamento & purificação
Coelhos
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Allergens); 0 (Antigens, Plant); 0 (Glycoproteins); 0 (Plant Proteins); 0 (Profilins)
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170911
[Lr] Data última revisão:
170911
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170128
[St] Status:MEDLINE



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