Base de dados : MEDLINE
Pesquisa : B01.650.940.800.575.912.250.618.100.060.560 [Categoria DeCS]
Referências encontradas : 8 [refinar]
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  1 / 8 MEDLINE  
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[PMID]:28634256
[Au] Autor:Kim C; Cameron KM; Kim JH
[Ad] Endereço:Department of Life Science, Gachon University, Seongnam 13120, Republic of Korea.
[Ti] Título:Molecular systematics and historical biogeography of s.s.
[So] Source:Am J Bot;104(6):939-952, 2017 Jun.
[Is] ISSN:1537-2197
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:PREMISE OF THE STUDY: Understanding the underlying mechanisms for the evolution of intercontinental disjunct patterns has long fascinated botanists. We present a molecular phylogenetic reconstruction of s.l. (including ) with a focus on s.s. species, which have a disjunct distribution between Eurasia and North America. Within this evolutionary framework, we clarify the systematic classification and biogeographical history of s.s. METHOD: Data from two nuclear and five chloroplast DNA regions were analyzed using the programs PAUP*, RAxML, MrBayes, BEAST, and RASP. KEY RESULTS: Our molecular phylogeny supports s.s. as monophyletic. and are grouped according to their taxonomic species, but the accessions of are divided into two well-defined groups, i.e., one comprising western North American accessions, and the other composed of northeast Asian accessions. Molecular dating and biogeographic reconstructions suggest a northeast Asian origin for s.s. and that a complicated pattern of divergent evolution began approximately in the late Miocene. Intercontinental disjunctions of s.s. in the Northern Hemisphere appear to have occurred two times during the Pliocene. CONCLUSIONS: Based on our results, two possible ways to treat s.s. species can be envisioned: (1) elevate Asian populations of to specific rank; or (2) combine the three s.s. species into a broadly defined single species. We recommend treatment of s.s. as a single species. The biogeographic patterns of s.s. coupled with molecular dating suggest both vicariance and long-distance dispersal events as key mechanisms for diversification of the clade.
[Mh] Termos MeSH primário: Evolução Biológica
Maianthemum/classificação
Filogenia
[Mh] Termos MeSH secundário: DNA de Cloroplastos/genética
DNA de Plantas/genética
América do Norte
Análise de Sequência de DNA
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (DNA, Chloroplast); 0 (DNA, Plant)
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171020
[Lr] Data última revisão:
171020
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170622
[St] Status:MEDLINE
[do] DOI:10.3732/ajb.1600454


  2 / 8 MEDLINE  
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[PMID]:25077951
[Au] Autor:Zhang L; Shi X; Si M; Li C; Zhu L; Zhao L; Shen X; Wang Y
[Ad] Endereço:State Key Laboratory of Crop Stress Biology for Arid Areas and College of Life Sciences, Northwest A&F University, Yangling, Shaanxi, 712100, People's Republic of China.
[Ti] Título:Rhizobium smilacinae sp. nov., an endophytic bacterium isolated from the leaf of Smilacina japonica.
[So] Source:Antonie Van Leeuwenhoek;106(4):715-23, 2014 Oct.
[Is] ISSN:1572-9699
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:During a study of endophytic bacteria from traditional Chinese medicinal plants, a bacterial strain, designated PTYR-5(T), was isolated from the leaf of Smilacina japonica A. Gray collected from Taibai Mountain in Shaanxi Province, north-west China. Phylogenetic analysis based on 16S rRNA gene sequences showed that strain PTYR-5(T) is a member of the genus Rhizobium, exhibiting the highest sequence similarities to R. cellulosilyticum LMG 23642(T) (97.2%), R. huautlense LMG 18254(T) (97.2%) and R. alkalisoli CCBAU 01393(T) (97.1%). The levels of 16S rRNA gene sequence similarity with respect to other Rhizobium species with validly published names were less than 97.0%. Phylogenies of the housekeeping genes atpD, recA and glnII confirmed its distinct position, showing low similarity with respect to those of recognized Rhizobium species (no more than 94.1, 90.0 and 88.0% similarity, respectively). The DNA-DNA relatedness values of strain PTYR-5(T) with R. cellulosilyticum LMG 23642(T), R. huautlense LMG 18254(T) and R. alkalisoli CCBAU 01393(T) were 33.6, 21.4 and 29.5 %, respectively. Based on phenotypic, phylogenetic and genotypic data, strain PTYR-5(T) is considered to represent a novel species of the genus Rhizobium, for which the name Rhizobium smilacinae sp. nov. is proposed. The type strain is PTYR-5(T) (=CCTCC AB 2013016(T)=KCTC 32300(T)=LMG 27604(T)).
[Mh] Termos MeSH primário: Maianthemum/microbiologia
Rhizobium/classificação
Rhizobium/isolamento & purificação
[Mh] Termos MeSH secundário: Técnicas de Tipagem Bacteriana
China
Análise por Conglomerados
DNA Bacteriano/química
DNA Bacteriano/genética
DNA Ribossômico/química
DNA Ribossômico/genética
Endófitos/classificação
Endófitos/genética
Endófitos/isolamento & purificação
Endófitos/fisiologia
Genes Bacterianos
Genes Essenciais
Dados de Sequência Molecular
Hibridização de Ácido Nucleico
Filogenia
Folhas de Planta/microbiologia
RNA Ribossômico 16S/genética
Rhizobium/genética
Rhizobium/fisiologia
Análise de Sequência de DNA
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (DNA, Bacterial); 0 (DNA, Ribosomal); 0 (RNA, Ribosomal, 16S)
[Em] Mês de entrada:1505
[Cu] Atualização por classe:161125
[Lr] Data última revisão:
161125
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:140801
[St] Status:MEDLINE
[do] DOI:10.1007/s10482-014-0241-1


  3 / 8 MEDLINE  
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[PMID]:23645023
[Au] Autor:Zhang L; Wang Y; Wei L; Wang Y; Shen X; Li S
[Ad] Endereço:State Key Laboratory of Crop Stress Biology for Arid Areas and College of Life Sciences, Northwest A&F University, Yangling, Shaanxi 712100, PR China.
[Ti] Título:Taibaiella smilacinae gen. nov., sp. nov., an endophytic member of the family Chitinophagaceae isolated from the stem of Smilacina japonica, and emended description of Flavihumibacter petaseus.
[So] Source:Int J Syst Evol Microbiol;63(Pt 10):3769-76, 2013 Oct.
[Is] ISSN:1466-5034
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:A light-yellow-coloured bacterium, designated strain PTJT-5(T), was isolated from the stem of Smilacina japonica A. Gray collected from Taibai Mountain in Shaanxi Province, north-west China, and was subjected to a taxonomic study by using a polyphasic approach. The novel isolate grew optimally at 25-28 °C and pH 6.0-7.0. Flexirubin-type pigments were produced. Cells were Gram-reaction-negative, strictly aerobic, rod-shaped and non-motile. Phylogenetic analysis based on 16S rRNA gene sequences showed that strain PTJT-5(T) was a member of the phylum Bacteroidetes, exhibiting the highest sequence similarity to Lacibacter cauensis NJ-8(T) (87.7 %). The major cellular fatty acids were iso-C15 : 0, iso-C15 : 1 G, iso-C17 : 0 and iso-C17 : 0 3-OH. The only polyamine was homospermidine and the major polar lipid was phosphatidylethanolamine. The only respiratory quinone was MK-7 and the DNA G+C content was 40.3 mol%. Based on the phenotypic, phylogenetic and genotypic data, strain PTJT-5(T) is considered to represent a novel species of a new genus in the family Chitinophagaceae, for which the name Taibaiella smilacinae gen. nov., sp. nov. is proposed. The type strain of Taibaiella smilacinae is PTJT-5(T) ( = CCTCC AB 2013017(T) = KCTC 32316(T)). An emended description of Flavihumibacter petaseus is also proposed.
[Mh] Termos MeSH primário: Bacteroidetes/classificação
Maianthemum/microbiologia
Filogenia
[Mh] Termos MeSH secundário: Técnicas de Tipagem Bacteriana
Bacteroidetes/genética
Bacteroidetes/isolamento & purificação
Composição de Bases
China
DNA Bacteriano/genética
Ácidos Graxos/análise
Dados de Sequência Molecular
Fosfatidiletanolaminas/análise
Caules de Planta/microbiologia
Polienos/análise
RNA Ribossômico 16S/genética
Análise de Sequência de DNA
Espermidina/análise
Vitamina K 2/análogos & derivados
Vitamina K 2/análise
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (DNA, Bacterial); 0 (Fatty Acids); 0 (Phosphatidylethanolamines); 0 (Polyenes); 0 (RNA, Ribosomal, 16S); 11032-49-8 (Vitamin K 2); 39382-08-6 (phosphatidylethanolamine); 54363-90-5 (flexirubins); 8427BML8NY (vitamin MK 7); U87FK77H25 (Spermidine)
[Em] Mês de entrada:1312
[Cu] Atualização por classe:161125
[Lr] Data última revisão:
161125
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:130507
[St] Status:MEDLINE
[do] DOI:10.1099/ijs.0.051607-0


  4 / 8 MEDLINE  
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[PMID]:22465215
[Au] Autor:Liu X; Zhang H; Niu XF; Xin W; Qi L
[Ad] Endereço:Faculty of Pharmacy, School of Medicine, Xi'an Jiaotong University, Xi'an 710061, PR China.
[Ti] Título:Steroidal saponins from Smilacina japonica.
[So] Source:Fitoterapia;83(4):812-6, 2012 Jun.
[Is] ISSN:1873-6971
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:Three new steroidal saponins, japonicoside A (1), japonicoside B (2) and japonicoside C (3) were isolated from the dried rhizomes and roots of Smilacina japonica A. Gray. Their structures were elucidated as (25S)-5α-spirostan-9(11)-en-3ß-ol 3-O-ß-D-glucopyranosyl-(1→2)-[ß-D-xylopyranosyl-(1→3)]-ß-D-glucopyranosyl-(1→4)-ß-D-galactopyranoside (1), (25S)-5α-spirostan-9(11)-en-3ß,17α-diol 3-O-ß-D-glucopyranosyl-(1→2)-[ß-D-xylopyranosyl-(1→3)]-ß-D-glucopyranosyl-(1→4)-ß-D-galactopyranoside (2) and (25S)-5α-spirostan-9(11)-en-3ß,17α,24α-triol 3-O-ß-D-glucopyranosyl-(1→2)-[ß-D-xylopyranosyl-(1→3)]-ß-D-glucopyranosyl-(1→4)-ß-D-galactopyranoside (3) on the basis of chemical methods and detailed spectroscopic analysis, including 1D, 2D NMR and HR-ESI-MS. The cytotoxicity of isolated compounds was evaluated in vitro for cytotoxic properties against human hepatocellular carcinoma cells (SMMC-7221) and human colorectal adenocarcinoma cells (DLD-1), respectively.
[Mh] Termos MeSH primário: Antineoplásicos Fitogênicos/isolamento & purificação
Maianthemum/química
Fitoterapia
Extratos Vegetais/química
Saponinas/isolamento & purificação
Esteroides/isolamento & purificação
[Mh] Termos MeSH secundário: Antineoplásicos Fitogênicos/farmacologia
Antineoplásicos Fitogênicos/uso terapêutico
Carcinoma Hepatocelular/tratamento farmacológico
Linhagem Celular Tumoral
Neoplasias Colorretais/tratamento farmacológico
Seres Humanos
Neoplasias Hepáticas/tratamento farmacológico
Estrutura Molecular
Extratos Vegetais/farmacologia
Extratos Vegetais/uso terapêutico
Raízes de Plantas
Rizoma
Saponinas/farmacologia
Saponinas/uso terapêutico
Esteroides/farmacologia
Esteroides/uso terapêutico
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Antineoplastic Agents, Phytogenic); 0 (Plant Extracts); 0 (Saponins); 0 (Steroids); 0 (japonicoside A); 0 (japonicoside B); 0 (japonicoside C)
[Em] Mês de entrada:1209
[Cu] Atualização por classe:161125
[Lr] Data última revisão:
161125
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:120403
[St] Status:MEDLINE
[do] DOI:10.1016/j.fitote.2012.03.018


  5 / 8 MEDLINE  
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[PMID]:22368855
[Au] Autor:Zhao S; Yang L; Han Z; Han M
[Ad] Endereço:College of Chinese Medicinal Materials, Jilin Agricultural University, Changchun 130118, China. zhsjlong@163.com
[Ti] Título:[Furosteroidal saponin from Smilacina japonica].
[So] Source:Zhongguo Zhong Yao Za Zhi;36(24):3453-6, 2011 Dec.
[Is] ISSN:1001-5302
[Cp] País de publicação:China
[La] Idioma:chi
[Ab] Resumo:Smilacina japonica is a perennial herb, belonging to Smilacina genus of Liliaceae. A new furosteroidal saponin (1) was isolated and purified from the ethanol extract of the rhizome of S. japonica by various column chromatography. Its structure was established as 26-O-beta-D-glucopyranosyl-(25R)-furost-5-en-3beta, 12, 17alpha, 22xi, 26-pentol-12-O-acetyle-3-O-alpha-L-rhamnopyranosyl-(1 --> 2)-beta-D-glucopyranoside by physical and chemical properties and IR, MS, 1D, 2D NMR techniques. It showed strong cytotoxicity against the SPC-A-1 cancer cell lines.
[Mh] Termos MeSH primário: Maianthemum/química
Saponinas/isolamento & purificação
[Mh] Termos MeSH secundário: Antineoplásicos Fitogênicos/farmacologia
Linhagem Celular Tumoral
Seres Humanos
Espectroscopia de Ressonância Magnética
Saponinas/química
Saponinas/farmacologia
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Antineoplastic Agents, Phytogenic); 0 (Saponins)
[Em] Mês de entrada:1203
[Cu] Atualização por classe:161125
[Lr] Data última revisão:
161125
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:120229
[St] Status:MEDLINE


  6 / 8 MEDLINE  
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[PMID]:18817798
[Au] Autor:Yang SL; Liu XK; Wu H; Wang HB; Qing C
[Ad] Endereço:State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, The Chinese Academy of Sciences, Kunming, Yunnan 650204, PR China.
[Ti] Título:Steroidal saponins and cytoxicity of the wild edible vegetable-Smilacina atropurpurea.
[So] Source:Steroids;74(1):7-12, 2009 Jan.
[Is] ISSN:0039-128X
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Four new steroidal saponins, smilacinoside A (1), B (2), C (3), and D (4), together with three known saponins, funkioside D (5), aspidistrin (6) and 26-O-beta-d-glucopyranosyl-22-methoxyl-(25R)-furost-5-en-3beta,26-diol 3-O-beta-d-glucopyranosyl-(1-->2)-beta-d-glucopyranosyl-(1-->4)-beta-d-galactopyranoside (7) were isolated from the dried tender aerial parts of Smilacina atropurpurea (Franch.) Wang et Tang. The structures of new compounds were elucidated as diosgenin 3-O-alpha-l-rhamnopyranosyl-(1-->2)-O-beta-d-galactopyranoside (1), diosgenin 3-O-alpha-l-rhamnopyranosyl-(1-->3)-[6-O-palmitoxyl]-O-beta-d-galactopyranoside (2), 26-O-beta-d-glucopyranosyl-(25R)-furost-5-en-3beta,22xi,26-triol 3-O-alpha-l-rhamnopyranosyl-(1-->2)}-beta-d-galactopyranoside (3) and 26-O-beta-d-glucopyranosyl-22-methoxyl-(25R)-furost-5-en-3beta,26-diol 3-O-alpha-l-rhamnopyranosyl-(1-->2)-beta-d-galactopyranoside (4) on the basis of chemical methods and detailed spectroscopic analysis, including 1D and 2D NMR techniques and single-crystal X-ray diffraction, respectively. Six of these compounds and MeOH extract were tested for their in vitro cytotoxicity toward K562 human tumor cells by an improved MTT method. Smilacinoside A, funkioside D and aspidistrin exhibited significant in vitro cytotoxicity against K562 with IC(50) values of 1.09, 2.93 and 0.47microg/mL, respectively.
[Mh] Termos MeSH primário: Citotoxinas/química
Maianthemum/química
Saponinas/química
Saponinas/farmacologia
Esteroides/química
Esteroides/farmacologia
[Mh] Termos MeSH secundário: Citotoxinas/isolamento & purificação
Citotoxinas/farmacologia
Seres Humanos
Células K562
Estrutura Molecular
Saponinas/isolamento & purificação
Esteroides/isolamento & purificação
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Cytotoxins); 0 (Saponins); 0 (Steroids)
[Em] Mês de entrada:0903
[Cu] Atualização por classe:161124
[Lr] Data última revisão:
161124
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:080927
[St] Status:MEDLINE
[do] DOI:10.1016/j.steroids.2008.08.008


  7 / 8 MEDLINE  
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[PMID]:17531386
[Au] Autor:Ban JY; Cho SO; Jeon SY; Bae K; Song KS; Seong YH
[Ad] Endereço:College of Veterinary Medicine, Chungbuk National University, Cheongju, Chungbuk 361-763, South Korea.
[Ti] Título:3,4-dihydroxybenzoic acid from Smilacis chinae rhizome protects amyloid beta protein (25-35)-induced neurotoxicity in cultured rat cortical neurons.
[So] Source:Neurosci Lett;420(2):184-8, 2007 Jun 13.
[Is] ISSN:0304-3940
[Cp] País de publicação:Ireland
[La] Idioma:eng
[Ab] Resumo:The neuroprotective effect of 3,4-dihydroxybenzoic acid (3,4-DHBA) isolated from Smilacis chinae rhizome against Abeta (25-35)-induced neurotoxicity on cultured rat cortical neurons was found in this study. The protective effect of 3,4-DHBA against Abeta (25-35)-induced neuronal cell death was investigated by measuring cell viability via a 3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyl-tetrazolium bromide (MTT) assay and Hoechst 33342 staining. 3,4-DHBA (1 and 10 microM) concentration-dependently inhibited 10 microM Abeta (25-35)-induced neuronal apoptotic death. 3,4-DHBA (1 and 10 microM) inhibited 10 microM Abeta (25-35)-induced elevation of cytosolic Ca(2+) concentration ([Ca(2+)](c)), which was measured by a fluorescent dye, Fluo-4 AM. 3,4-DHBA also inhibited glutamate release into medium, reactive oxygen species (ROS) generation, and caspase-3 activation, which were induced by 10 microM Abeta (25-35). These results suggest that 3,4-DHBA prevents Abeta (25-35)-induced neuronal cell damage by interfering with the increase of [Ca(2+)](c), and then by inhibiting glutamate release, generation of ROS and caspase-3 activity.
[Mh] Termos MeSH primário: Doença de Alzheimer/tratamento farmacológico
Peptídeos beta-Amiloides/antagonistas & inibidores
Córtex Cerebral/efeitos dos fármacos
Hidroxibenzoatos/farmacologia
Degeneração Neural/tratamento farmacológico
Fármacos Neuroprotetores/farmacologia
Fragmentos de Peptídeos/antagonistas & inibidores
[Mh] Termos MeSH secundário: Doença de Alzheimer/metabolismo
Doença de Alzheimer/fisiopatologia
Peptídeos beta-Amiloides/toxicidade
Animais
Cálcio/metabolismo
Sinalização do Cálcio/efeitos dos fármacos
Sinalização do Cálcio/fisiologia
Caspase 3/metabolismo
Inibidores de Caspase
Sobrevivência Celular/efeitos dos fármacos
Sobrevivência Celular/fisiologia
Células Cultivadas
Córtex Cerebral/patologia
Córtex Cerebral/fisiopatologia
Citoproteção/efeitos dos fármacos
Citoproteção/fisiologia
Ácido Glutâmico/metabolismo
Indicadores e Reagentes
Maianthemum/química
Degeneração Neural/induzido quimicamente
Degeneração Neural/prevenção & controle
Neurônios/efeitos dos fármacos
Neurônios/metabolismo
Fragmentos de Peptídeos/toxicidade
Ratos
Ratos Sprague-Dawley
Espécies Reativas de Oxigênio/antagonistas & inibidores
Espécies Reativas de Oxigênio/metabolismo
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Amyloid beta-Peptides); 0 (Caspase Inhibitors); 0 (Hydroxybenzoates); 0 (Indicators and Reagents); 0 (Neuroprotective Agents); 0 (Peptide Fragments); 0 (Reactive Oxygen Species); 0 (amyloid beta-protein (25-35)); 36R5QJ8L4B (protocatechuic acid); 3KX376GY7L (Glutamic Acid); EC 3.4.22.- (Caspase 3); SY7Q814VUP (Calcium)
[Em] Mês de entrada:0708
[Cu] Atualização por classe:161124
[Lr] Data última revisão:
161124
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:070529
[St] Status:MEDLINE


  8 / 8 MEDLINE  
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[PMID]:16766007
[Au] Autor:Zhang Y; Li HZ; Zhang YJ; Jacob MR; Khan SI; Li XC; Yang CR
[Ad] Endereço:State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, PR China
[Ti] Título:Atropurosides A-G, new steroidal saponins from Smilacina atropurpurea.
[So] Source:Steroids;71(8):712-9, 2006 Aug.
[Is] ISSN:0039-128X
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Atropurosides A-G (1-7), seven new steroidal saponins, which possess new polyhydroxylated aglycones, were isolated from the rhizomes of Smilacina atropurpurea (Convallariaceae), together with a known saponin, dioscin (8). Their structures were elucidated on the basis of detailed spectroscopic analysis, including 1D and 2D NMR techniques and chemical methods. Antifungal testing of the eight compounds indicated that atropurosides B (2) and F (6) were fungicidal against Candida albicans, Candida glabrata, Cryptococcus neoformans, and Aspergillus fumigatus with minimum fungicidal concentrations (MFCs) < or = 20 microg/ml, while dioscin (8) was selectively active against C. albicans and C. glabrata (MFC < or = 5.0 microg/ml). Furthermore, the antifungal saponins 2, 6, and 8 were evaluated for their in vitro cytotoxicities in a panel of human cancer cell lines (SK-MEL, KB, BT-549, SK-OV-3, and HepG2) and non-cancerous Vero cells. All showed moderate cytotoxicities. It appears that the antifungal activity of these steroidal saponins correlates with their cytotoxicity against mammalian cells.
[Mh] Termos MeSH primário: Maianthemum/química
Saponinas/isolamento & purificação
Esteroides/isolamento & purificação
[Mh] Termos MeSH secundário: Animais
Antifúngicos/farmacologia
Antineoplásicos Fitogênicos/farmacologia
Aspergillus fumigatus/efeitos dos fármacos
Candida/efeitos dos fármacos
Cercopithecus aethiops
Cryptococcus neoformans/efeitos dos fármacos
Seres Humanos
Testes de Sensibilidade Microbiana
Fitosteróis/isolamento & purificação
Extratos Vegetais/química
Extratos Vegetais/farmacologia
Saponinas/farmacologia
Esteroides/farmacologia
Relação Estrutura-Atividade
Células Tumorais Cultivadas/efeitos dos fármacos
Células Vero/efeitos dos fármacos
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, N.I.H., EXTRAMURAL; RESEARCH SUPPORT, U.S. GOV'T, NON-P.H.S.
[Nm] Nome de substância:
0 (Antifungal Agents); 0 (Antineoplastic Agents, Phytogenic); 0 (Phytosterols); 0 (Plant Extracts); 0 (Saponins); 0 (Steroids)
[Em] Mês de entrada:0610
[Cu] Atualização por classe:161124
[Lr] Data última revisão:
161124
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:060613
[St] Status:MEDLINE



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BIREME/OPAS/OMS - Centro Latino-Americano e do Caribe de Informação em Ciências da Saúde