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Pesquisa : B01.650.940.800.575.912.250.715.249 [Categoria DeCS]
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[PMID]:28397417
[Au] Autor:Adetunji OA; Odeniyi MA
[Ad] Endereço:Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, University of Ibadan, Ibadan, Nigeria.
[Ti] Título:Material and Compression Properties of Cedrela odorata Gum Co-Processed with Plantain Starch and Microcrystalline Cellulose.
[So] Source:Polim Med;46(1):35-43, 2016 Jan-Jun.
[Is] ISSN:0370-0747
[Cp] País de publicação:Poland
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Many excipients used in tableting exhibit some undesirable properties such as poor flow, cohesion and lubricating characteristics, thus necessitating some modification to achieve the desired product. OBJECTIVES: The objective of this study was to enhance the material, flow and compressional properties of Cedrela odorata gum (COG) (Family: Meliaceae) by co-processing with plantain starch (PS) and microcrystalline cellulose (MCC). MATERIAL AND METHODS: The COG was co-processed with PS (or MCC) by physical co-grinding at ratio 1 : 1, 1 : 2 and 1 : 4, and characterized using morphological analysis, swelling index viscosity measurements, particle size analysis and FTIR spectra. The material, flow and compressional properties of the co-processed excipients were also evaluated. Results were analyzed using mean and standard deviation of data. RESULTS: There was a decrease in the degree of agglomeration of COG and a reduction in the size of the powdered gum. The co-processed excipients were more spherical than the native excipients. The COG had the highest viscosity, while MCC and COG : PS (1 : 2) showed the highest and lowest degrees of swelling at 27.0 ± 0.05°C respectively. Water absorption capacity of the component excipients improved with co-processing COG : MCC increasing from 171.8 ± 1.54 (1 : 1) to 214.8 ± 1.07 (1 : 2), while COG : PS increased from 95.2 ± 0.08 (1 : 1) to 206.2 ± 0.13. There was a decrease in the percentage solubility of the co-processed excipients with the highest and lowest solubility observed in COG (54.1 ± 0.07%) and PS (3.7 ± 0.16%), respectively. The FTIR spectra indicate no significant interaction between the excipients. The poor flow of the component excipients did not improve with co-processing; however, there was a significant increase in compressibility. Generally, COG co-processed with MCC showed better compression properties when compared with COG co-processed with PS. CONCLUSIONS: Co-processing of COD with MC or PS enhanced the characters of the component excipients, thus making the co-processed excipients suitable for direct compression of tablets without altering the chemical nature of the component excipients.
[Mh] Termos MeSH primário: Química Farmacêutica
Excipientes/química
Gomas Vegetais/química
Amido/química
Comprimidos/química
[Mh] Termos MeSH secundário: Cedrela/química
Tamanho da Partícula
Plantago/química
Solubilidade
Espectroscopia de Infravermelho com Transformada de Fourier
Viscosidade
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Excipients); 0 (Plant Gums); 0 (Tablets); 9005-25-8 (Starch)
[Em] Mês de entrada:1707
[Cu] Atualização por classe:170713
[Lr] Data última revisão:
170713
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170412
[St] Status:MEDLINE
[do] DOI:10.17219/pim/64924


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[PMID]:27732622
[Au] Autor:Estrada-Contreras I; Equihua M; Laborde J; Martínez Meyer E; Sánchez-Velásquez LR
[Ad] Endereço:Ambiente y Sustentabilidad, Instituto de Ecología A.C., Xalapa-Enríquez, Veracruz, Mexico.
[Ti] Título:Current and Future Distribution of the Tropical Tree Cedrela odorata L. in Mexico under Climate Change Scenarios Using MaxLike.
[So] Source:PLoS One;11(10):e0164178, 2016.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Climate change is recognized as an important threat to global biodiversity because it increases the risk of extinction of many species on the planet. Mexico is a megadiverse country and native tree species such as red cedar (Cedrela odorata) can be used to maintain forests while helping mitigate climate change, because it is considered a fast growing pioneer species with great economic potential in the forestry industry. In order to assess possible shifts in areas suitable for C. odorata plantations in Mexico with ecological niche models, we used the MaxLike algorithm, climate variables, the geo-referenced records of this species, three general circulation models and three scenarios of future emissions. Results show a current potential distribution of 573,079 km2 with an average probability of occurrence of 0.93 (± 0.13). The potential distribution area could increase up to 650,356 km2 by 2060 according to the general circulation model HADCM3 B2, with an average probability of occurrence of 0.86 (± 0.14). Finally, we delimited an area of 35,377 km2 that has a high potential for the establishment of C. odorata plantations, by selecting those sites with optimal conditions for its growth that are outside protected areas and are currently devoid of trees. C. odorata has a significant potential to help in the mitigation of the effects of climate change. Using MaxLike we identified extense areas in Mexico suitable to increase carbon sequestration through plantations of this highly valued native tree species.
[Mh] Termos MeSH primário: Cedrela/crescimento & desenvolvimento
Mudança Climática
Árvores/crescimento & desenvolvimento
[Mh] Termos MeSH secundário: Algoritmos
Biodiversidade
Sequestro de Carbono
Simulação por Computador
Florestas
México
Modelos Biológicos
Probabilidade
Clima Tropical
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1705
[Cu] Atualização por classe:170529
[Lr] Data última revisão:
170529
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161013
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0164178


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[PMID]:27243585
[Au] Autor:Siqueira-Silva AI; Pereira EG; Modolo LV; Lemos-Filho JP; Paiva EA
[Ad] Endereço:Departamento de Botânica, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, 31270-901, Belo Horizonte, MG, Brazil.
[Ti] Título:Impact of cement dust pollution on Cedrela fissilis Vell. (Meliaceae): A potential bioindicator species.
[So] Source:Chemosphere;158:56-65, 2016 Sep.
[Is] ISSN:1879-1298
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Considering the impacts caused to vegetation in the vicinity of cement factories, the aim of this study was to evaluate the impacts of cement dust on the structural organization and physiological/biochemical traits of Cedrela fissilis leaflets, a woody species native to tropical America. Plants were exposed to 2.5 or 5 mg cm-2 cement dust applied to the leaf surface, to the soil or simultaneously to the leaf surface and the soil.. Leaves of shoot-treated plants exhibited chlorosis, marginal and inter veins necrosis, diminished thickness, epidermal cells less turgid, cellular collapse, obstructed stomata, senescence, rolling and some abscission. In few cases, individual death was recorded. Cement dust-treated plants also presented decreased amount of photosynthetic pigments and iron (Fe) and increase in calcium (Ca) levels. The cement crust formed in leaves surface blocked from 30 to 50% of the incoming light and reduced the stomatal conductance and the potential quantum yield of photosystem II. Control or soil-treated plants did not exhibit morphophysiological changes throughout the experiment. The activity of superoxide dismutase, catalase and ascorbate peroxidase increased in leaves of plants upon treatment with 2.5 mg cm(-2) cement dust, independent of the site application. Overall, these results indicate that C. fissilis is highly sensitive to cement dust at the initial stage of development.
[Mh] Termos MeSH primário: Cedrela/efeitos dos fármacos
Materiais de Construção
Poluentes Ambientais/análise
Folhas de Planta/efeitos dos fármacos
[Mh] Termos MeSH secundário: Antioxidantes/química
Ascorbato Peroxidases/química
Catalase/química
Poeira
Concentração de Íons de Hidrogênio
Ferro/química
Luz
Microscopia Eletrônica
Fotossíntese
Complexo de Proteína do Fotossistema II
Folhas de Planta/fisiologia
Solo/química
Superóxido Dismutase/química
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Antioxidants); 0 (Dust); 0 (Environmental Pollutants); 0 (Photosystem II Protein Complex); 0 (Soil); E1UOL152H7 (Iron); EC 1.11.1.11 (Ascorbate Peroxidases); EC 1.11.1.6 (Catalase); EC 1.15.1.1 (Superoxide Dismutase)
[Em] Mês de entrada:1703
[Cu] Atualização por classe:171116
[Lr] Data última revisão:
171116
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160601
[St] Status:MEDLINE


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[PMID]:27215942
[Au] Autor:Zelener N; Tosto D; de Oliveira LO; Soldati MC; Inza MV; Fornes LF
[Ad] Endereço:Instituto de Recursos Biológicos, INTA Castelar-CIRN-CNIA, De los Reseros y N. Repetto (ex Las Cabañas) s.n., Hurlingham 1686, Buenos Aires, Argentina. Electronic address: noga.zelener@gmail.com.
[Ti] Título:Molecular evidence of hybrid zones of Cedrela (Meliaceae) in the Yungas of Northwestern Argentina.
[So] Source:Mol Phylogenet Evol;102:45-55, 2016 Sep.
[Is] ISSN:1095-9513
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:In the Yungas of Northwestern Argentina, three endangered species of Cedrela (C. angustifolia, C. saltensis, and C. balansae) follow altitudinal gradients of distribution with contact zones between them. We sampled 210 individuals from 20 populations that spanned most of Cedrela's geographical range in the Yungas, and used Amplified Fragment Length Polymorphism (AFLP) markers and DNA sequences of the nuclear Internal Transcribed Spacer (ITS) to investigate hybrid zones. Data analyses employed an array of complementary methods, including principal coordinate analyses, Bayesian clustering analyses, maximum likelihood tree-building, and network techniques. Both nuclear molecular systems - AFLP and ITS - provided insights into the evolutionary history of Cedrela in the Yungas in a congruent manner. We uncovered strong support for the occurrence of natural hybridization between C. balansae and C. saltensis. Additionally, we identified hybrid zones in areas of sympatry (at both the Calilegua National Park and the San Andrés farm) and in transition zones from 820 to 1100meters above sea level (localities of Pintascayo and Acambuco). There was no evidence for hybridization of either C. balansae or C. saltensis with C. angustifolia. The role of hybrid populations in conservation and use of genetic resources in the Yungas were discussed.
[Mh] Termos MeSH primário: Cedrela/genética
Ecossistema
Hibridização Genética
[Mh] Termos MeSH secundário: Análise do Polimorfismo de Comprimento de Fragmentos Amplificados
Argentina
Teorema de Bayes
Análise por Conglomerados
Bases de Dados Genéticas
Genética Populacional
Geografia
Filogenia
Análise de Componente Principal
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170925
[Lr] Data última revisão:
170925
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160525
[St] Status:MEDLINE


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[PMID]:26838366
[Au] Autor:Mangaravite É; Vinson CC; Rody HV; Garcia MG; Carniello MA; Silva RS; Oliveira LO
[Ad] Endereço:Universidade Federal de Viçosa, Instituto de Biotechnologia Aplicada à Agropecuária 36570-000; Viçosa, MG, Brazil.
[Ti] Título:Contemporary patterns of genetic diversity of cedrela fissilis offer insight into the shaping of seasonal forests in eastern South America.
[So] Source:Am J Bot;103(2):307-16, 2016 Feb.
[Is] ISSN:1537-2197
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:PREMISE OF THE STUDY: We investigated how genetic diversity is distributed across the range of Cedrela fissilis, a tree species associated with seasonal neotropical forests, to gain insights into competing biogeographic scenarios that explain how disjunct distributions of these forests were shaped. METHODS: A total of 250 samples were sampled from 18 sites across the species' range in Brazil and eastern Bolivia and genotyped with 10 microsatellite loci. An array of complementary methods-F statistics, analyses of molecular variance (AMOVA), and clustering analyses-assessed genetic diversity, population differentiation, and structure. KEY RESULTS: Most of the genetic diversity (82.5%) was partitioned within populations, but about 12% was due to differences among groups of populations on either side of the Cerrado or located within the Cerrado; mean expected heterozygosity and mean observed heterozygosity were 0.821 and 0.704, respectively. The 250 samples were sorted into two Bayesian groups: one group for each side of the Cerrado. The populations showed varying levels of admixture, with the greatest admixture evident in populations located toward central Brazil. CONCLUSIONS: In C. fissilis, genetic diversity is structured according to geography: the Atlantic range and the Chiquitano range each harbor a genealogical lineage. Interfertility and varying levels of admixture between lineages provide strong evidence that the lineages evolved under geographic, but not genetic, isolation. Admixture is of recent origin, owing to population expansion. Cedrela fissilis shares this dual pattern of distribution of genetic diversity with other phylogenetically unrelated taxa that are typically associated with seasonal forests.
[Mh] Termos MeSH primário: Cedrela/crescimento & desenvolvimento
Florestas
Variação Genética
[Mh] Termos MeSH secundário: Bolívia
Brasil
Estações do Ano
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Em] Mês de entrada:1609
[Cu] Atualização por classe:160218
[Lr] Data última revisão:
160218
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160204
[St] Status:MEDLINE
[do] DOI:10.3732/ajb.1500370


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Martins, Domingos Tabajara de Oliveira
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[PMID]:25562721
[Au] Autor:Giordani MA; Collicchio TC; Ascêncio SD; Martins DT; Balogun SO; Bieski IG; da Silva LA; Colodel EM; de Souza RL; de Souza DL; de França SA; Andrade CM; Kawashita NH
[Ad] Endereço:Department of Chemistry, Biochemistry Laboratory, Federal University of Mato Grosso (UFMT), Avenida Fernando Correa da Costa, 2367, Boa Esperança, CEP: 78060-900, Cuiabá, Mato Grosso, Brazil.
[Ti] Título:Hydroethanolic extract of the inner stem bark of Cedrela odorata has low toxicity and reduces hyperglycemia induced by an overload of sucrose and glucose.
[So] Source:J Ethnopharmacol;162:352-61, 2015 Mar 13.
[Is] ISSN:1872-7573
[Cp] País de publicação:Ireland
[La] Idioma:eng
[Ab] Resumo:ETHNOPHARMACOLOGICAL RELEVANCE: Cedrela odorata L. (Meliaceae) is a native plant of the Amazon region and its inner stem bark is used in the treatment of diabetes in the form of maceration in Brazilian popular medicine. Until now, there is no scientific study on this activity. The present study was aimed at evaluating the anti-hyperglycemic activity, anti-diabetic, toxicity, antioxidant and potential mechanism of action of hydroethanolic extract of the inner stem bark of Cedrela odorata. MATERIAL AND METHODS: The inner stem bark extract of Cedrela odorata was prepared by maceration in 70% ethanol for 7 days to obtain hydroethanolic extract of Cedrela odorata (HeECo). The preliminary phytochemical analysis was performed according to procedures described in the literature. Selected secondary metabolites detected were quantified by high performance liquid chromatography (HPLC). Acute toxicity of HeECo was investigated in male and female mice with oral administration of graded doses of HeECo from 10 to 5000 mg/kg. Subchronic oral toxicity study was done by oral administration of HeECo (500 mg/kg) and vehicle for 30 days to both sexes of Wistar rats. Clinical observations and toxicological related parameters were determined. Blood was collected for biochemical and hematological analyses, while histological examinations were performed on selected organs. Anti-hiperglycemic and antidiabetic effects were evaluated in streptozotocin-induced diabetic rats. In acute evaluation, the animals received pretreatment with 250 and 500 mg/kg of HeECo, before carbohydrate overload. For subchronic effect, the antidiabetic activity of HeECo was evaluated using the same doses for 21 days. At the end of the treatments, the levels of triacylglycerols, malondialdehyde, total antioxidant status, superoxide dismutase and glutathione peroxidase activities were evaluated in the plasma. RESULTS: The extract showed low acute toxicity. HeECo exhibited inhibitory activity against α-glucosidase and caused a lowering in the peak levels of blood glucose in animals that received glucose overload by 36.7% and 24.1% in the area under the glucose curve (AUC). When the overload was sucrose, HeECo reduced the blood glucose level by 44.4% without affecting AUC. Treatment with HeECo of the blood glucose of the diabetic animals for 21 days did not lead to improvement in weight gain and regularization of the blood glucose level, but reduced the triacylglycerol and malondialdehyde levels by 36.6% and 48.1%, respectively. The activity of the antioxidant enzymes, superoxide dismutase and glutathione peroxidase were significantly increased when compared to diabetic control rats. HPLC analysis showed the presence of polyphenols, such as gallic acid, (-)- gallocatechin and (+)- catechin, the latter is present in higher quantity. CONCLUSIONS: Collectively, these data showed that HeECo could blunt the postprandial glycemic surge in rats; possibly through inhibition of alpha-glucosidase and positive modulation of antioxidant enzymes. Our findings confirmed the anti-hiperglycemic activity of HeECo in STZ- diabetic rats. Cedrela odorata is effective in diminishing glucose levels in vitro and in vivo and in ameliorating oxidative damage that occurs in diabetes and/or due to hyperglycemia in rats. According to our results, the efficacy of Cedrela odorata preparation could be due to the presence of active principles with different mode of actions at the molecular level, including α-glycosidases and glucose transporter inhibitors and antioxidant property.
[Mh] Termos MeSH primário: Cedrela/química
Glucose/administração & dosagem
Hiperglicemia/induzido quimicamente
Casca de Planta/química
Extratos Vegetais/farmacologia
Sacarose/administração & dosagem
[Mh] Termos MeSH secundário: Animais
Feminino
Hiperglicemia/tratamento farmacológico
Masculino
Medicina Tradicional
Camundongos
Extratos Vegetais/efeitos adversos
Extratos Vegetais/química
Caules de Planta/química
Ratos
Ratos Wistar
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Plant Extracts); 57-50-1 (Sucrose); IY9XDZ35W2 (Glucose)
[Em] Mês de entrada:1603
[Cu] Atualização por classe:150217
[Lr] Data última revisão:
150217
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:150107
[St] Status:MEDLINE


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[PMID]:25176241
[Au] Autor:Ahmad R; Ahmad M; Mehjabeen; Jahan N
[Ad] Endereço:Research Institute of Pharmaceutical Sciences, Faculty of Pharmacy, University of Karachi, Karachi, Pakistan.
[Ti] Título:Phytochemical screening and anti-oxidant activity of the two plants Ziziphus oxyphylla Edgew and Cedrela serrata Royle.
[So] Source:Pak J Pharm Sci;27(5 Spec no):1477-82, 2014 Sep.
[Is] ISSN:1011-601X
[Cp] País de publicação:Pakistan
[La] Idioma:eng
[Ab] Resumo:Phytochemical studies of medicinal plants are a basic and helping tool for the isolation of active secondary metabolites. The isolation of active compounds is made easy by the help of preliminary phytochemical studies, which shows the presence of a specific class or group of compounds present in these medicinal plants. Ziziphus oxyphylla and Cedrela serrata are medicinal plants with valuable local uses. The present study is for the first Phytochemical investigation of these two medicinal plants which consists of, Quantitative tests showing very good results except Ziziphus oxyphylla plants which does not showed the results for Ester value and Peroxide value. Color reactions are studied for all the crude extracts showing the presence of a number of chemical groups belonging to the class of Alkaloids, Phenol compounds, Phenothiazines, Aromatic compounds, Amino acids, Sulfur compounds etc. Brine shrimp activity was performed which showed a LD50 value of 45.74 and 53.36 in the case of Ziziphus oxyphylla roots and Cedrela serrata bark respectively, which is comparable to the standard drug Cyclophosphamide results of 16.09. Insecticidal activity did not show any promising result indicating the absence of any insect killing potency. Antioxidant activity was very positive for all the extract particularly, the Ziziphus oxyphylla roots, which showed even better results than the standard drug Ascorbic acid used in various dilutions.
[Mh] Termos MeSH primário: Antioxidantes/química
Cedrela
Preparações de Plantas/química
Ziziphus
[Mh] Termos MeSH secundário: Animais
Antioxidantes/isolamento & purificação
Antioxidantes/toxicidade
Artemia/efeitos dos fármacos
Compostos de Bifenilo/química
Cedrela/química
Cor
Dose Letal Mediana
Fitoterapia
Picratos/química
Casca de Planta
Folhas de Planta
Preparações de Plantas/isolamento & purificação
Preparações de Plantas/toxicidade
Raízes de Plantas
Plantas Medicinais
Tribolium/efeitos dos fármacos
Ziziphus/química
[Pt] Tipo de publicação:COMPARATIVE STUDY; JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Antioxidants); 0 (Biphenyl Compounds); 0 (Picrates); 0 (Plant Preparations); DFD3H4VGDH (1,1-diphenyl-2-picrylhydrazyl)
[Em] Mês de entrada:1411
[Cu] Atualização por classe:161125
[Lr] Data última revisão:
161125
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:140902
[St] Status:MEDLINE


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Texto completo SciELO Brasil
[PMID]:25140505
[Au] Autor:Masetto TE; Faria JM; Fraiz AC
[Ad] Endereço:Faculdade de Ciências Agrárias, Universidade Federal da Grande Dourados/UFGD, Dourados, MS, Brasil.
[Ti] Título:Re-induction of desiccation tolerance after germination of Cedrela fissilis Vell. seeds.
[So] Source:An Acad Bras Cienc;86(3):1273-86, 2014 Sep.
[Is] ISSN:1678-2690
[Cp] País de publicação:Brazil
[La] Idioma:eng
[Ab] Resumo:This work aimed to characterize the re-induction of desiccation tolerance (DT) in germinated seeds, using polyethylene glycol (PEG 8000). Cell changes were investigated through cytological assays (cell viability and transmission electronic microscopy) as well as DNA integrity during loss and re-establishment of DT. The loss of DT was characterized by drying germinated seeds with different radicle lengths (1, 2, 3, 4 and 5 mm) in silica gel, decreasing the moisture content to ten percentage points intervals, followed by pre-humidification (100% RH / 24 h) and rehydration. To re-induce DT, germinated seeds were treated for 72 h with PEG (-2.04 MPa) and PEG (-2.04 MPa) + ABA (100 µM) before dehydration. Germinated seeds did not tolerate desiccation to 10% moisture content, irrespectively of the radicle length. However, when incubated in PEG, those with 1 and 2 mm long radicle attained 71% and 29% survival, respectively. The PEG+ABA treatment was efficient to re-establish DT in seeds with 1 mm long radicles (100% survival). The ultrastructural assays of the cells of germinated seeds with 2 and 5 mm length confirmed the obtained physiological results. Germinated seeds of C. fissilis constitute a useful tool for desiccation tolerance investigations.
[Mh] Termos MeSH primário: Cedrela/crescimento & desenvolvimento
Dessecação
Germinação/fisiologia
Sementes/fisiologia
[Mh] Termos MeSH secundário: Adaptação Fisiológica/fisiologia
Cedrela/fisiologia
Cedrela/ultraestrutura
Microscopia Eletrônica de Varredura
Polietilenoglicóis
Sementes/ultraestrutura
Fatores de Tempo
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
30IQX730WE (Polyethylene Glycols)
[Em] Mês de entrada:1501
[Cu] Atualização por classe:151119
[Lr] Data última revisão:
151119
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:140821
[St] Status:MEDLINE


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[PMID]:25102658
[Au] Autor:Pereyra Espinoza MJ; Inga Guillen GJ; Santos Morales M; Arisméndiz Rodríguez R
[Ti] Título:[Cedrela odorata (Meliaceae) potential for dendrochronological studies in the Selva Central of Perú].
[Ti] Título:Potencialidad de Cedrela odorata (Meliaceae) para estudios dendrocronológicos en la selva central del Perú..
[So] Source:Rev Biol Trop;62(2):783-93, 2014 Jun.
[Is] ISSN:0034-7744
[Cp] País de publicação:Costa Rica
[La] Idioma:spa
[Ab] Resumo:Despite the progress made during the past 20 years, searching dendrochronological potential in tropical and subtropical tree species, tropical dendrochronology, is still in a development stage. The aim of this research was to determine the potential of C. odorata for dendrochronological studies in the Selva Central of Perú. The tree-ring anatomical characteristics were carefully examined and we were able to develop a 215 year (1795-2 009) tree-ring chronology and correlate it with precipitation records. The tree-ring chronology was developed based on 47 series of 27 trees. Tree rings are clearly delimited by large pore diameters in earlywood and small ones in latewood associated with marginal and paratracheal parenchyma. The tree-ring chronology was related to precipitation records from Satipo and significant correlations were found with the previous rainy season and late dry season of the current growth period. Moreover, we found close relationship between tree growth and total precipitations of the hydrological period (December to September) for the interval 1990-2009. These results demonstrate the influence of rainfall at different stages of C. odorata radial growth. The good discrimination of annual rings, strong relationship with precipitation, the wide range and longevity of trees (200 years) make C. odorata a very promising species for dendrochronological studies in tropical and subtropical forest of America.
[Mh] Termos MeSH primário: Cedrela/crescimento & desenvolvimento
Chuvas
Árvores/crescimento & desenvolvimento
[Mh] Termos MeSH secundário: Peru
Estações do Ano
Clima Tropical
Madeira/anatomia & histologia
[Pt] Tipo de publicação:ENGLISH ABSTRACT; JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Em] Mês de entrada:1409
[Cu] Atualização por classe:140808
[Lr] Data última revisão:
140808
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:140809
[St] Status:MEDLINE


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[PMID]:24841003
[Au] Autor:Wu WB; Zhang H; Dong SH; Sheng L; Wu Y; Li J; Yue JM
[Ad] Endereço:a State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences , Shanghai 201203 , China.
[Ti] Título:New triterpenoids with protein tyrosine phosphatase 1B inhibition from Cedrela odorata.
[So] Source:J Asian Nat Prod Res;16(7):709-16, 2014.
[Is] ISSN:1477-2213
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Two new apotirucallane-type triterpenoids, cedrodorols A-B (1 and 2), along with seven known compounds (3-9), were isolated from the twigs and leaves of Cedrela odorata. Their structures were elucidated on the basis of extensive spectroscopic analysis. Compounds 1 and 2 showed significant inhibitory activity against protein tyrosine phosphatase 1B (PTP1B) with the IC50 values of 13.09 and 3.93 µg/ml, respectively.
[Mh] Termos MeSH primário: Cedrela/química
Medicamentos de Ervas Chinesas/isolamento & purificação
Medicamentos de Ervas Chinesas/farmacologia
Proteína Tirosina Fosfatase não Receptora Tipo 1/antagonistas & inibidores
Triterpenos/isolamento & purificação
Triterpenos/farmacologia
[Mh] Termos MeSH secundário: Medicamentos de Ervas Chinesas/química
Concentração Inibidora 50
Estrutura Molecular
Ressonância Magnética Nuclear Biomolecular
Folhas de Planta/química
Caules de Planta/química
Triterpenos/química
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Drugs, Chinese Herbal); 0 (Triterpenes); 0 (apotirucallane); 0 (cedrodorol A); 0 (cedrodorol B); EC 3.1.3.48 (Protein Tyrosine Phosphatase, Non-Receptor Type 1)
[Em] Mês de entrada:1410
[Cu] Atualização por classe:140731
[Lr] Data última revisão:
140731
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:140521
[St] Status:MEDLINE
[do] DOI:10.1080/10286020.2014.919281



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