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Pesquisa : B01.650.940.800.575.912.250.735 [Categoria DeCS]
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[PMID]:29202738
[Au] Autor:Schink M; Dehus O
[Ad] Endereço:Helixor Heilmittel GmbH, 72348, Rosenfeld, Germany. mschink@helixor.de.
[Ti] Título:Effects of mistletoe products on pharmacokinetic drug turnover by inhibition and induction of cytochrome P450 activities.
[So] Source:BMC Complement Altern Med;17(1):521, 2017 Dec 04.
[Is] ISSN:1472-6882
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: European mistletoe (Viscum album) products used in cancer therapy are frequently combined with other anti-cancer-drugs. Hence, potential herb-drug interactions have become a major safety concern in mistletoe therapy. METHODS: Three European mistletoe products (Helixor® A, Helixor® M and Helixor® P from mistletoe grown on firs, apple trees and pines, respectively) were tested for inhibition of nine major cytochrome P450 (CYP) isoenzymes in a test system using pooled human liver microsomes and for induction of five CYP isoforms in human hepatocytes cultivated in vitro according to the relevant guideline. RESULTS: Major inhibition did not occur in any of the CYP marker reactions. For some CYP isoenzymes, a minor or intermediate inhibition could be observed, but without dose effect relationship. Induction activity (≥ 1.5-fold increase) was not found with any of the three mistletoe products. CONCLUSION: Since no induction capacity was found and major inhibition above 50% did not occur even with the highest concentration used, which is approximately 100,000-fold higher than the clinically relevant dose in plasma, a clinically relevant herb-drug interaction is not expected for Helixor® A, M, and P.
[Mh] Termos MeSH primário: Antineoplásicos/farmacologia
Inibidores das Enzimas do Citocromo P-450/farmacologia
Sistema Enzimático do Citocromo P-450/efeitos dos fármacos
Erva-de-Passarinho
Extratos Vegetais/farmacologia
[Mh] Termos MeSH secundário: Sistema Enzimático do Citocromo P-450/metabolismo
Feminino
Hepatócitos/efeitos dos fármacos
Seres Humanos
Masculino
Microssomos Hepáticos/efeitos dos fármacos
Microssomos Hepáticos/metabolismo
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Antineoplastic Agents); 0 (Cytochrome P-450 Enzyme Inhibitors); 0 (Plant Extracts); 75882-01-8 (Helixor); 9035-51-2 (Cytochrome P-450 Enzyme System)
[Em] Mês de entrada:1712
[Cu] Atualização por classe:171220
[Lr] Data última revisão:
171220
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171206
[St] Status:MEDLINE
[do] DOI:10.1186/s12906-017-2028-1


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[PMID]:28923036
[Au] Autor:Huber R; Schlodder D; Effertz C; Rieger S; Tröger W
[Ad] Endereço:Center for Complementary Medicine, University Medical Center Freiburg, Faculty of Medicine, University of Freiburg, Breisacher Str. 115B, 79106, Freiburg im Breisgau, Germany. roman.huber@uniklinik-freiburg.de.
[Ti] Título:Safety of intravenously applied mistletoe extract - results from a phase I dose escalation study in patients with advanced cancer.
[So] Source:BMC Complement Altern Med;17(1):465, 2017 Sep 18.
[Is] ISSN:1472-6882
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Mistletoe extracts have anti-tumor properties and are approved for subcutaneous use in cancer patients. Data on Intravenous application are limited. METHODS: An aqueous extract from pine-mistletoe was used to investigate maximum tolerable dose (MTD) and safety of intravenous application. It was infused once weekly for 3 weeks in patients with advanced cancer. Any type of cancer was included; relevant exclusion criteria were concurrent chemo- or radiation therapy. The classical phase I 3 + 3 dose escalation scheme was followed. Predefined dose groups were 200, 400, 700, 1200 and 2000 mg. Maximum planned dose was 2000 mg. With the MTD three more patients should be treated for 9 weeks in order to evaluate intermediate term tolerability. Weekly during the treatment and 1 week later tolerability, clinical status, safety laboratory parameters and adverse events were documented. RESULTS: Twenty-one patients (3 in the dose groups 200, 400, 700 and 1200 mg, respectively, 9 in the dose group 2000 mg) were included. MTD was not reached. Because one dose-limiting toxicity (DLT), an allergic reaction, occurred during infusion of 2000 mg, three more patients had to be included in this dose group and tolerated it, as well as the three patients who received 2000 mg for 9 weeks. Occasionally in the dose group 2000 mg mild to moderate fever occurred. CONCLUSION: Weekly infusions of 2000 mg of the pine-mistletoe extract were tolerated and can be used in further studies but had a risk for allergic reactions and fever. German Clinical Trials Register (Trial registration number DRKS00005028).
[Mh] Termos MeSH primário: Antineoplásicos Fitogênicos/administração & dosagem
Erva-de-Passarinho/química
Neoplasias/tratamento farmacológico
Extratos Vegetais/administração & dosagem
[Mh] Termos MeSH secundário: Adulto
Idoso
Antineoplásicos Fitogênicos/efeitos adversos
Relação Dose-Resposta a Droga
Feminino
Alemanha
Seres Humanos
Infusões Intraventriculares
Masculino
Meia-Idade
Neoplasias/imunologia
Extratos Vegetais/efeitos adversos
Estudos Prospectivos
[Pt] Tipo de publicação:CLINICAL TRIAL, PHASE I; JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Antineoplastic Agents, Phytogenic); 0 (Plant Extracts)
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171016
[Lr] Data última revisão:
171016
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170920
[St] Status:MEDLINE
[do] DOI:10.1186/s12906-017-1971-1


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[PMID]:28417943
[Au] Autor:Pietrzak W; Nowak R; Gawlik-Dziki U; Lemieszek MK; Rzeski W
[Ad] Endereço:Department of Pharmaceutical Botany, Medical University of Lublin, Chodzki 1 Str., 20-093 Lublin, Poland. wioleta.pietrzak@umlub.pl.
[Ti] Título:LC-ESI-MS/MS Identification of Biologically Active Phenolic Compounds in Mistletoe Berry Extracts from Different Host Trees.
[So] Source:Molecules;22(4), 2017 Apr 12.
[Is] ISSN:1420-3049
[Cp] País de publicação:Switzerland
[La] Idioma:eng
[Ab] Resumo:A new, rapid, sensitive and selective liquid chromatography-electrospray ionization-tandem mass spectrometry (LC-ESI-MS/MS) method was developed to determine the content of flavonoid aglycones and phenolic acids in mistletoe berries ( L.) harvested from six different Polish host trees. Additionally, the total phenolic content (TPC) and total flavonoid content (TFC) as well as an antioxidant and antiproliferative activity were evaluated for the first time. The plant material was selectively extracted using ultrasound assisted maceration with methanol/water (8:2) solution. The obtained TPC and TFC results varied from 7.146 to 9.345 mg GA g ¹ and from 1.888 to 2.888 mg Q g of dry extracts, respectively. The LC-ESI-MS/MS analysis demonstrated the highest content of phenolic acids in mistletoe berries from 'Italica' L. and flavonoid aglycones in mistletoe berries from Mill. (354.45 µg and 5.955 µg per g dry extract, respectively). The moderate antioxidant activity of investigated extracts was obtained. The studies revealed that the examined extracts decreased the proliferation of human colon adenocarcinoma cells line LS180 in a dose-dependent manner without cytotoxicity in the human colon epithelial cell line CCD 841 CoTr. Moreover, the obtained results suggest considerable impact of polyphenols on the anticancer activity of these extracts.
[Mh] Termos MeSH primário: Frutas/química
Erva-de-Passarinho/química
Fenóis/química
Extratos Vegetais/química
Extratos Vegetais/farmacologia
[Mh] Termos MeSH secundário: Antineoplásicos Fitogênicos/química
Antineoplásicos Fitogênicos/farmacologia
Antioxidantes/química
Antioxidantes/farmacologia
Cromatografia Líquida
Depuradores de Radicais Livres/química
Depuradores de Radicais Livres/farmacologia
Seres Humanos
Compostos Fitoquímicos/química
Espectrometria de Massas por Ionização por Electrospray
Espectrometria de Massas em Tandem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Antineoplastic Agents, Phytogenic); 0 (Antioxidants); 0 (Free Radical Scavengers); 0 (Phenols); 0 (Phytochemicals); 0 (Plant Extracts)
[Em] Mês de entrada:1705
[Cu] Atualização por classe:170531
[Lr] Data última revisão:
170531
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170419
[St] Status:MEDLINE


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[PMID]:27899327
[Au] Autor:Watson DM; Milner KV; Leigh A
[Ad] Endereço:School of Environmental Science, Charles Sturt University, Albury 2640, Australia. Electronic address: dwatson@csu.edu.au.
[Ti] Título:Novel application of species richness estimators to predict the host range of parasites.
[So] Source:Int J Parasitol;47(1):31-39, 2017 Jan.
[Is] ISSN:1879-0135
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Host range is a critical life history trait of parasites, influencing prevalence, virulence and ultimately determining their distributional extent. Current approaches to measure host range are sensitive to sampling effort, the number of known hosts increasing with more records. Here, we develop a novel application of results-based stopping rules to determine how many hosts should be sampled to yield stable estimates of the number of primary hosts within regions, then use species richness estimation to predict host ranges of parasites across their distributional ranges. We selected three mistletoe species (hemiparasitic plants in the Loranthaceae) to evaluate our approach: a strict host specialist (Amyema lucasii, dependent on a single host species), an intermediate species (Amyema quandang, dependent on hosts in one genus) and a generalist (Lysiana exocarpi, dependent on many genera across multiple families), comparing results from geographically-stratified surveys against known host lists derived from herbarium specimens. The results-based stopping rule (stop sampling bioregion once observed host richness exceeds 80% of the host richness predicted using the Abundance-based Coverage Estimator) worked well for most bioregions studied, being satisfied after three to six sampling plots (each representing 25 host trees) but was unreliable in those bioregions with high host richness or high proportions of rare hosts. Although generating stable predictions of host range with minimal variation among six estimators trialled, distribution-wide estimates fell well short of the number of hosts known from herbarium records. This mismatch, coupled with the discovery of nine previously unrecorded mistletoe-host combinations, further demonstrates the limited ecological relevance of simple host-parasite lists. By collecting estimates of host range of constrained completeness, our approach maximises sampling efficiency while generating comparable estimates of the number of primary hosts, with broad applicability to many host-parasite systems.
[Mh] Termos MeSH primário: Parasitos/classificação
Plantas/parasitologia
[Mh] Termos MeSH secundário: Animais
Austrália
Biodiversidade
Especificidade de Hospedeiro
Interações Hospedeiro-Parasita
Erva-de-Passarinho
Doenças das Plantas/parasitologia
Especificidade da Espécie
Árvores/parasitologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1707
[Cu] Atualização por classe:170731
[Lr] Data última revisão:
170731
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161201
[St] Status:MEDLINE


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[PMID]:27845200
[Au] Autor:Lim NJ; Shin JH; Kim HJ; Lim Y; Kim JY; Lee WJ; Han SJ; Kwon O
[Ad] Endereço:Department of Nutritional Science and Food Management, Ewha Womans University, Seoul 03760, Republic of Korea.
[Ti] Título:A combination of Korean mistletoe extract and resistance exercise retarded the decline in muscle mass and strength in the elderly: A randomized controlled trial.
[So] Source:Exp Gerontol;87(Pt A):48-56, 2017 Jan.
[Is] ISSN:1873-6815
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Given the increased concerns about the degenerative decline in the physical performance of the elderly, there is a need for developing effective strategies to suppress the age-related loss of skeletal muscle mass and functional capacity through a lifestyle intervention. This randomized controlled trial examined whether a combination of Korean mistletoe extract (KME) supplement and exercise affected muscle mass, muscle function, and targeted molecular expressions. Sixty-seven subjects aged 55-75years were assigned to placebo, low-dose (1g/d), or high-dose (2g/d) of KME for 12weeks. The body composition was significantly changed in the high-dose group during the intervention period as determined by skeletal muscle mass (P=0.040), fat free mass (P=0.042), soft lean mass (P=0.023), skeletal muscle index (P=0.041), fat-free mass index (P=0.030), percent body fat (P=0.044), and fat mass to lean mass ratio (P=0.030). Knee strength was measured by Cybex, demonstrating a significant effect in the KME groups compared to the placebo group (P=0.026 for peak torque and P=0.057 for set total work), which was more pronounced after adjusting for age, gender, protein, and energy intake (P=0.009 for peak torque and P=0.033 for set total work). The dynamic balance ability was remarkably improved in the high-dose group over a 12-week period as determined by Timed "Up and Go" (P=0.005 for fast walk test and P=0.024 for ordinary walk test). Consistent with these results, RT-PCR, multiplex analyses, and immunocytofluorescence staining revealed that a high-dose KME supplementation was effective for suppressing intracellular pathways related to muscle protein degradation, but stimulating those related to myogenesis. In particular, significant differences were found in atrogin-1 mRNA (P=0.002 at a single administration and P=0.001 at a 12-week administration), myogenin mRNA (P<0.0001 at a single administration and P=0.040 at a 12-week administration), and insulin growth factor 1 receptor phosphorylation (P=0.002 at a 12-week administration). These results suggest that KME supplementation together with resistance exercise may be useful in suppressing the age-related loss of muscle mass and strength in the elderly.
[Mh] Termos MeSH primário: Envelhecimento/efeitos dos fármacos
Erva-de-Passarinho/química
Força Muscular/efeitos dos fármacos
Músculo Esquelético/fisiologia
Extratos Vegetais/farmacologia
Sarcopenia/tratamento farmacológico
[Mh] Termos MeSH secundário: Idoso
Composição Corporal
Feminino
Seres Humanos
Masculino
Meia-Idade
Proteínas Musculares/genética
Proteínas Musculares/metabolismo
Músculo Esquelético/efeitos dos fármacos
Tamanho do Órgão/efeitos dos fármacos
RNA Mensageiro/análise
Receptores de Somatomedina/genética
Receptores de Somatomedina/metabolismo
República da Coreia
Proteínas Ligases SKP Culina F-Box/genética
Proteínas Ligases SKP Culina F-Box/metabolismo
[Pt] Tipo de publicação:JOURNAL ARTICLE; RANDOMIZED CONTROLLED TRIAL
[Nm] Nome de substância:
0 (IGF1R protein, human); 0 (Muscle Proteins); 0 (Plant Extracts); 0 (RNA, Messenger); 0 (Receptors, Somatomedin); EC 2.3.2.27 (FBXO32 protein, human); EC 2.3.2.27 (SKP Cullin F-Box Protein Ligases)
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171016
[Lr] Data última revisão:
171016
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161116
[St] Status:MEDLINE


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[PMID]:27716052
[Au] Autor:Wang Y; Li X; Zhou W; Li T; Tian C
[Ad] Endereço:The Key Laboratory for Silviculture and Conservation of Ministry of Education, College of Forestry, Beijing Forestry University, Beijing, China. ylwang@bjfu.edu.cn.
[Ti] Título:De novo assembly and transcriptome characterization of spruce dwarf mistletoe Arceuthobium sichuanense uncovers gene expression profiling associated with plant development.
[So] Source:BMC Genomics;17(1):771, 2016 10 01.
[Is] ISSN:1471-2164
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: The parasitic flowering plant dwarf mistletoe (Arceuthobium spp., Viscaceae) is one of the most destructive forest pests, posing a major threat to numerous conifer species worldwide. Arceuthobium sichuanense (spruce dwarf mistletoe, SDM) infects Qinghai spruce (Picea crassifolia) and causes severe damage to spruce forests in Northwest China. SDM is a Chinese native parasitic plant and acquires carbohydrates and mineral nutrition from its hosts. However, underlying molecular basis of the physiological development is largely unknown. Investigations of these physiological traits have been hampered by the lack of genomic resources for this species. RESULTS: In this study, to investigate the transcriptomic processes underlying physiological traits and development in SDM, we used RNA from four major tissues (i.e., shoots, flowers, fruits, and seeds) for de novo assembly and to annotate the transcriptome of this species. We uncovered the annotated transcriptome and performed whole genome expression profiling to uncover transcriptional dynamics during physiological development, and we identified key gene categories involved in the process of sexual development. The assembled SDM transcriptome reported in this work contains 331,347 assembled transcripts; 226,687 unigenes were functionally annotated by Gene Ontology analysis. RNA-Seq analysis using this reference transcriptome identified 22,641 differentially expressed genes from shoots, flowers, fruits, and seeds. These genes are enriched in processes including organic substance metabolism, cellular metabolism, biosynthesis, and cellular component. In addition, genes related to transport, transcription, hormone biosynthesis and signaling, carbohydrate metabolism, and photosynthesis were differentially expressed between tissues. CONCLUSION: This work reveals tissue-specific gene expression patterns and pathways of SDM and implied to a difference between photosynthetic and non-photosynthetic tissues in plants. The data can potentially be used for future investigations on endophytic parasitism and SDM-spruce interaction, and it dramatically increases the available genomic resources for Arceuthobium and dwarf mistletoe communities. This preliminary study of the Arceuthobium transcriptome provides excellent opportunities for characterizing plant parasitic genes with unknown functions.
[Mh] Termos MeSH primário: Perfilação da Expressão Gênica
Regulação da Expressão Gênica no Desenvolvimento
Regulação da Expressão Gênica de Plantas
Erva-de-Passarinho/genética
Desenvolvimento Vegetal/genética
Transcriptoma
[Mh] Termos MeSH secundário: China
Análise por Conglomerados
Biologia Computacional/métodos
Genes de Plantas
Sequenciamento de Nucleotídeos em Larga Escala
Anotação de Sequência Molecular
Especificidade de Órgãos/genética
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Em] Mês de entrada:1708
[Cu] Atualização por classe:171119
[Lr] Data última revisão:
171119
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161008
[St] Status:MEDLINE


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[PMID]:27606463
[Au] Autor:Gschwendtner KM; Holmberg C; Weis J
[Ad] Endereço:Klinik für Tumorbiologie, UKF Reha Gmbh, Universitätsklinikum Freiburg, Freiburg i.Br., Deutschland.
[Ti] Título:[Beweggründe von Krebspatienten für und gegen die Inanspruchnahme der Misteltherapie].
[So] Source:Forsch Komplementmed;23(4):215-22, 2016.
[Is] ISSN:1661-4127
[Cp] País de publicação:Switzerland
[La] Idioma:ger
[Ab] Resumo:Einleitung: Die Misteltherapie ist im deutschsprachigen Raum ein häufig angewandtes komplementärmedizinisches Verfahren (KM) in der Onkologie. Diese Studie hatte das Ziel, die Beweggründe für oder gegen eine Inanspruchnahme der Misteltherapie zu untersuchen und Themenfeldern zuzuordnen. Patienten und Methoden: Es wurden qualitative leitfadengestützte Interviews mit Krebspatienten geführt. Der Interviewleitfaden fragte nach der Inanspruchnahme von KM, der Motivation zur Inanspruchnahme, Informationsverhalten und -bedürfnissen zu KM sowie nach der Krebserkrankung. Um die Beweggründe für die Inanspruchnahme oder Nichtinanspruchnahme der Misteltherapie zu verstehen, wurden die Interviews inhaltsanalytisch ausgewertet. Ergebnisse: Insgesamt wurden Interviews mit 88 Krebspatienten geführt, davon nutzen 18 (20,5%) die Misteltherapie. Die Beweggründe für oder gegen eine Inanspruchnahme der Misteltherapie ließen sich den 2 Themenfeldern «Wahrgenommene Indikation¼ und «Abwägungen bei der Entscheidungsfindung¼ zuordnen. Diskussion und Schlussfolgerungen: Mit der Misteltherapie wird sowohl ein Einfluss auf das Tumorwachstum als auch eine supportive Wirkung assoziiert. Anwender sehen die Misteltherapie als sicheres Verfahren; Nichtnutzer befürchten eher Neben- oder Wechselwirkungen. Die Empfehlung von Fachpersonal spielt eine wichtige Rolle bei der Inanspruchnahme. Zum Teil waren die Nichtnutzer interessiert an der Anwendung der Misteltherapie, befanden sich jedoch noch im Klärungsprozess.
[Mh] Termos MeSH primário: Terapias Complementares
Erva-de-Passarinho
Neoplasias/tratamento farmacológico
Aceitação pelo Paciente de Cuidados de Saúde
Fitoterapia
Extratos Vegetais/uso terapêutico
[Mh] Termos MeSH secundário: Adulto
Feminino
Seres Humanos
Entrevista Psicológica
Masculino
Meia-Idade
Satisfação do Paciente
Extratos Vegetais/efeitos adversos
Pesquisa Qualitativa
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Plant Extracts)
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170817
[Lr] Data última revisão:
170817
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160909
[St] Status:MEDLINE
[do] DOI:10.1159/000448745


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[PMID]:27548121
[Au] Autor:Lim YC; Rajabalaya R; Lee SH; Tennakoon KU; Le QV; Idris A; Zulkipli IN; Keasberry N; David SR
[Ad] Endereço:Pengiran Anak Puteri Rashidah Sa'adatul Bolkiah Institute of Health Sciences, Universiti Brunei Darussalam, Jalan Tungku Link, BE 1410 Gadong, Brunei. yachee.lim@ubd.edu.bn.
[Ti] Título:Parasitic Mistletoes of the Genera Scurrula and Viscum: From Bench to Bedside.
[So] Source:Molecules;21(8), 2016 Aug 17.
[Is] ISSN:1420-3049
[Cp] País de publicação:Switzerland
[La] Idioma:eng
[Ab] Resumo:The mistletoes, stem hemiparasites of Asia and Europe, have been used as medicinal herbs for many years and possess sophisticated systems to obtain nutrients from their host plants. Although knowledge about ethnomedicinal uses of mistletoes is prevalent in Asia, systematic scientific study of these plants is still lacking, unlike its European counterparts. This review aims to evaluate the literature on Scurrula and Viscum mistletoes. Both mistletoes were found to have anticancer, antimicrobial, antioxidant and antihypertensive properties. Plants from the genus Scurrula were found to inhibit cancer growth due to presence of phytoconstituents such as quercetin and fatty acid chains. Similar to plants from the genus Viscum, Scurrula also possesses TNFα activity to strengthen the immune system to combat cancer. In line with its anticancer activity, both mistletoes are rich in antioxidants that confer protection against cancer as well as neurodegeneration. Extracts from plants of both genera showed evidence of vasodilation and thus, antihypertensive effects. Other therapeutic effects such as weight loss, postpartum and gastrointestinal healing from different plants of the genus Scurrula are documented. As the therapeutic effects of plants from Scurrula are still in exploration stage, there is currently no known clinical trial on these plants. However, there are few on-going clinical trials for Viscum album that demonstrate the functionalities of these mistletoes. Future work required for exploring the benefits of these plants and ways to develop both parasitic plants as a source of pharmacological drug are explained in this article.
[Mh] Termos MeSH primário: Erva-de-Passarinho/fisiologia
Extratos Vegetais/farmacologia
Plantas Medicinais/fisiologia
[Mh] Termos MeSH secundário: Animais
Anti-Infecciosos/química
Anti-Infecciosos/farmacologia
Anti-Hipertensivos/química
Anti-Hipertensivos/farmacologia
Antineoplásicos Fitogênicos/química
Antineoplásicos Fitogênicos/farmacologia
Antioxidantes/química
Antioxidantes/farmacologia
China
Etnofarmacologia
Europa (Continente)
Seres Humanos
Erva-de-Passarinho/química
Extratos Vegetais/química
Plantas Medicinais/química
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Nm] Nome de substância:
0 (Anti-Infective Agents); 0 (Antihypertensive Agents); 0 (Antineoplastic Agents, Phytogenic); 0 (Antioxidants); 0 (Plant Extracts)
[Em] Mês de entrada:1704
[Cu] Atualização por classe:170414
[Lr] Data última revisão:
170414
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160823
[St] Status:MEDLINE


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[PMID]:27395176
[Au] Autor:Heredia MD; Robbins RK
[Ad] Endereço:Cra. 76A, N° 9A-34, Apto. 404, Cali, Colombia.; Email: mdheredia@hotmail.com.
[Ti] Título:Natural history of the mistletoe-feeding Thereus lomalarga (Lepidoptera, Lycaenidae, Eumaeini) in Colombia.
[So] Source:Zootaxa;4117(3):301-20, 2016 Jun 01.
[Is] ISSN:1175-5334
[Cp] País de publicação:New Zealand
[La] Idioma:eng
[Ab] Resumo:The natural history and morphology of the immature stages of the butterfly Thereus lomalarga Robbins, Heredia & Busby are described and illustrated. The food plant is Oryctanthus alveolatus (H.B.K.) Kuijt (Loranthaceae). Chaetotaxy of the first instar is described and compared with that of three locally studied Thereus species. Larvae have four instars, and the dorsal nectary organ becomes functional in the third instar. They are facultatively tended by ants belonging to seven genera that are attracted to O. alveolatus by floral disc nectaries, honeydew producing Hemiptera, and secretory wounds produced by Hemiptera on the fleshy inflorescence rachis. The average period from egg to eclosion under lab conditions was 35.68 days. Females emerged before males. Adults of both sexes feed on nectar from the flowers of the food plant and on hemipteran secretions; adults were not observed feeding on other flowers. Campopleginae and Chalcidinae were the most important parasitoids.
[Mh] Termos MeSH primário: Borboletas/fisiologia
Erva-de-Passarinho/parasitologia
[Mh] Termos MeSH secundário: Distribuição Animal
Estruturas Animais/anatomia & histologia
Estruturas Animais/crescimento & desenvolvimento
Animais
Tamanho Corporal
Borboletas/anatomia & histologia
Borboletas/classificação
Borboletas/crescimento & desenvolvimento
Colômbia
Ecossistema
Comportamento Alimentar
Feminino
Larva/anatomia & histologia
Larva/classificação
Larva/crescimento & desenvolvimento
Masculino
Tamanho do Órgão
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1702
[Cu] Atualização por classe:170223
[Lr] Data última revisão:
170223
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160711
[St] Status:MEDLINE
[do] DOI:10.11646/zootaxa.4117.3.1


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[PMID]:27307210
[Au] Autor:Cocoletzi E; Angeles G; Ceccantini G; Patrón A; Ornelas JF
[Ad] Endereço:Red de Ecología Funcional, Instituto de Ecología, AC, Xalapa, Veracruz 91070 México.
[Ti] Título:Bidirectional anatomical effects in a mistletoe-host relationship: Psittacanthus schiedeanus mistletoe and its hosts Liquidambar styraciflua and Quercus germana.
[So] Source:Am J Bot;103(6):986-97, 2016 06.
[Is] ISSN:1537-2197
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:PREMISE OF THE STUDY: During the interactions between a parasitic plant and its host, the parasite affects its host morphologically, anatomically, and physiologically, yet there has been little focus on the effect of hosts on the parasite. Here, the functional interactions between the hemiparasitic mistletoe Psittacanthus schiedeanus and its hosts Liquidambar styraciflua and Quercus germana were interpreted based on the anatomical features of the vascular tissues. METHODS: Using standard techniques for light and transmission electron microscopy, we studied the effects of P. schiedeanus on the phloem anatomy of Liquidambar styraciflua and Quercus germana and vice versa. KEY RESULTS: The phloem of P. schiedeanus has larger sieve elements, companion cells, and sieve plate areas when it is parasitizing L. styraciflua than Q. germana; however, the parasite produces systemic effects on the phloem of its hosts, reducing the size of phloem in L. styraciflua but increasing it in Q. germana. Those seem to be the bidirectional effects. No direct connections between the secondary phloem of the parasite and that of its hosts were observed. Parenchymatic cells of L. styraciflua in contact with connective parenchyma cells of the parasite develop half-plasmodesmata, while those of Q. germana do not. CONCLUSIONS: The bidirectional effects between the parasite and its hosts comprise modifications in secondary phloem that are potentially affected by the phenology of its hosts, a combination of hormonal agents such as auxins, and the symplasmic or apoplasmic pathway for solutes import.
[Mh] Termos MeSH primário: Interações Hospedeiro-Parasita
Liquidambar/anatomia & histologia
Liquidambar/parasitologia
Erva-de-Passarinho/anatomia & histologia
Quercus/anatomia & histologia
Quercus/parasitologia
[Mh] Termos MeSH secundário: Liquidambar/citologia
Liquidambar/ultraestrutura
Floema/anatomia & histologia
Floema/citologia
Floema/ultraestrutura
Caules de Planta/anatomia & histologia
Caules de Planta/citologia
Quercus/citologia
Quercus/ultraestrutura
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Em] Mês de entrada:1707
[Cu] Atualização por classe:171121
[Lr] Data última revisão:
171121
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160617
[St] Status:MEDLINE
[do] DOI:10.3732/ajb.1600166



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