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  1 / 20 MEDLINE  
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[PMID]:26832428
[Au] Autor:Semprini A; Braithwaite I; Corin A; Sheahan D; Tofield C; Helm C; Montgomery B; Fingleton J; Weatherall M; Beasley R
[Ad] Endereço:Medical Research Institute of New Zealand, Wellington, New Zealand.
[Ti] Título:Randomised controlled trial of topical kanuka honey for the treatment of acne.
[So] Source:BMJ Open;6(2):e009448, 2016 Feb 01.
[Is] ISSN:2044-6055
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:OBJECTIVE: To investigate the efficacy of Honevo, a topical 90% medical-grade kanuka honey, and 10% glycerine (honey product) as a treatment for facial acne. DESIGN: Randomised controlled trial with single blind assessment of primary outcome variable. SETTING: Outpatient primary care from 3 New Zealand localities. PARTICIPANTS: Of 136 participants aged between 16 and 40 years with a diagnosis of acne and baseline Investigator's Global Assessment (IGA) for acne score of ≥ 2.68, participants were randomised to each treatment arm. INTERVENTIONS: All participants applied Protex, a triclocarban-based antibacterial soap twice daily for 12 weeks. Participants randomised to the honey product treatment arm applied this directly after washing off the antibacterial soap, twice daily for 12 weeks. OUTCOME MEASURES: The primary outcome was ≥ 2 point decrease in IGA score from baseline at 12 weeks. Secondary outcomes included mean lesion counts and changes in subject-rated acne improvement and severity at weeks 4 and 12, and withdrawals for worsening acne. RESULTS: 4/53 (7.6%) participants in the honey product group and 1/53 (1.9%) of participants in the control group had a ≥ 2 improvement in IGA score at week 12, compared with baseline, OR (95% CI) for improvement 4.2 (0.5 to 39.3), p=0.17. There were 15 and 14 participants who withdrew from the honey product group and control group, respectively. CONCLUSIONS: This randomised controlled trial did not find evidence that addition of medical-grade kanuka honey in combination with 10% glycerine to standard antibacterial soap treatment is more effective than the use of antibacterial soap alone in the treatment of acne. TRIAL REGISTRATION NUMBER: ACTRN12614000003673; Results.
[Mh] Termos MeSH primário: Acne Vulgar/terapia
Glicerol/uso terapêutico
Mel
Kunzea
[Mh] Termos MeSH secundário: Administração Tópica
Adolescente
Adulto
Antibacterianos/uso terapêutico
Terapia Combinada
Feminino
Glicerol/efeitos adversos
Mel/efeitos adversos
Seres Humanos
Masculino
Método Simples-Cego
Sabões
Resultado do Tratamento
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE; MULTICENTER STUDY; RANDOMIZED CONTROLLED TRIAL; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Anti-Bacterial Agents); 0 (Soaps); PDC6A3C0OX (Glycerol)
[Em] Mês de entrada:1610
[Cu] Atualização por classe:170220
[Lr] Data última revisão:
170220
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160203
[St] Status:MEDLINE
[do] DOI:10.1136/bmjopen-2015-009448


  2 / 20 MEDLINE  
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[PMID]:26304441
[Au] Autor:Bong J; Loomes KM; Schlothauer RC; Stephens JM
[Ad] Endereço:School of Biological Sciences and Institute for Innovation in Biotechnology, University of Auckland, PB92019 Auckland, New Zealand.
[Ti] Título:Fluorescence markers in some New Zealand honeys.
[So] Source:Food Chem;192:1006-14, 2016 Feb 01.
[Is] ISSN:0308-8146
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:The fluorescence characteristics of various New Zealand honeys were investigated to establish if this technique might detect signatures unique to manuka (Leptospermum scoparium) and kanuka (Kunzea ericoides) honeys. We found unique fluorescence profiles for these honeys which distinguished them from other New Zealand honey floral types. Two excitation-emission (ex-em) marker wavelengths each for manuka and kanuka honeys were identified; manuka honey at 270-365 (MM1) and 330-470 (MM2) nm and kanuka honey at 275-305 (KM1) and 445-525 (KM2) nm. Dilution of manuka and kanuka honeys with other honey types that did not possess these fluorescence profiles resulted in a proportional reduction in fluorescence signal of the honeys at the marker wavelengths. By comparison, rewarewa (Knightia excelsa), kamahi (Weinmannia racemosa), and clover (Trifolium spp.) honeys did not exhibit unique fluorescence patterns. These findings suggests that a fluorescence-based screening approach has potential utility for determining the monoflorality status of manuka and kanuka honeys.
[Mh] Termos MeSH primário: Mel/análise
Mel/classificação
Espectrometria de Fluorescência/métodos
[Mh] Termos MeSH secundário: Flores/classificação
Fluorescência
Kunzea
Leptospermum
Nova Zelândia
Pólen/química
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Em] Mês de entrada:1604
[Cu] Atualização por classe:150825
[Lr] Data última revisão:
150825
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:150826
[St] Status:MEDLINE


  3 / 20 MEDLINE  
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[PMID]:24582465
[Au] Autor:Chen CC; Yan SH; Yen MY; Wu PF; Liao WT; Huang TS; Wen ZH; David Wang HM
[Ad] Endereço:Department of Internal Medicine, Renai Branch, Taipei City Hospital, Taiwan, ROC.
[Ti] Título:Investigations of kanuka and manuka essential oils for in vitro treatment of disease and cellular inflammation caused by infectious microorganisms.
[So] Source:J Microbiol Immunol Infect;49(1):104-11, 2016 Feb.
[Is] ISSN:1995-9133
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Diseases caused by infectious and inflammatory microorganisms are among the most common and most severe nosocomial diseases worldwide. Therefore, developing effective agents for treating these illnesses is critical. In this study, essential oils from two tea tree species, kanuka (Kunzea ericoides) and manuka (Leptospermum scoparium), were evaluated for use in treating diseases and inflammation caused by microorganism infection. METHODS: Isolates of clinically common bacteria and fungi were obtained from American Type Culture Collection and from Kaohsiung Veterans General Hospital. Minimum inhibitory concentrations for Trichosporon mucoides, Malassezia furfur, Candida albicans, and Candida tropicalis were determined by the broth microdilution method with Sabouraud dextrose broth. The antibacterial susceptibility of Staphylococcus aureus, Streptococcus sobrinus, Streptococcus mutans, and Escherichia coli were determined by the broth microdilution method. A human acute monocytic leukemia cell line (THP-1) was cultured to test the effects of the essential oils on the release of the two inflammatory cytokines, tumor necrosis factor-α and interleukin-4. RESULTS: Multiple analyses of microorganism growth confirmed that both essential oils significantly inhibited four fungi and the four bacteria. The potent fungicidal properties of the oils were confirmed by minimum inhibitory concentrations ranging from 0.78% to 3.13%. The oils also showed excellent bactericidal qualities with 100% inhibition of the examined bacteria. In THP-1 cells, both oils lowered tumor necrosis factor-α released after lipopolysaccharide stimulation. Finally, the antimicrobial and anti-inflammatory effects of the oils were obtained without adversely affecting the immune system. CONCLUSION: These results indicate that the potent antimicroorganism and anti-inflammation properties of kanuka and manuka essential oils make them strong candidates for use in treating infections and immune-related disease. The data confirm the potential use of kanuka and manuka extracts as pharmaceutical antibiotics, medical cosmetology agents, and food supplements.
[Mh] Termos MeSH primário: Anti-Infecciosos/farmacologia
Anti-Inflamatórios/farmacologia
Bactérias/efeitos dos fármacos
Fungos/efeitos dos fármacos
Monócitos/efeitos dos fármacos
Óleos Voláteis/farmacologia
[Mh] Termos MeSH secundário: Anti-Infecciosos/isolamento & purificação
Anti-Inflamatórios/isolamento & purificação
Linhagem Celular
Seres Humanos
Interleucina-4/secreção
Kunzea/química
Leptospermum/química
Testes de Sensibilidade Microbiana
Óleos Voláteis/isolamento & purificação
Fator de Necrose Tumoral alfa/secreção
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Anti-Infective Agents); 0 (Anti-Inflammatory Agents); 0 (IL4 protein, human); 0 (Oils, Volatile); 0 (Tumor Necrosis Factor-alpha); 207137-56-2 (Interleukin-4)
[Em] Mês de entrada:1611
[Cu] Atualização por classe:161230
[Lr] Data última revisão:
161230
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:140304
[St] Status:MEDLINE


  4 / 20 MEDLINE  
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[PMID]:26109117
[Au] Autor:Braithwaite I; Hunt A; Riley J; Fingleton J; Kocks J; Corin A; Helm C; Sheahan D; Tofield C; Montgomery B; Holliday M; Weatherall M; Beasley R
[Ad] Endereço:Medical Research Institute of New Zealand, Wellington, New Zealand.
[Ti] Título:Randomised controlled trial of topical kanuka honey for the treatment of rosacea.
[So] Source:BMJ Open;5(6):e007651, 2015 Jun 24.
[Is] ISSN:2044-6055
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:OBJECTIVE: To investigate the efficacy of topical 90% medical-grade kanuka honey and 10% glycerine (Honevo) as a treatment for rosacea. DESIGN: Randomised controlled trial with blinded assessment of primary outcome variable. SETTING: Outpatient primary healthcare population from 5 New Zealand sites. PARTICIPANTS: 138 adults aged ≥ 16, with a diagnosis of rosacea, and a baseline blinded Investigator Global Assessment of Rosacea Severity Score (IGA-RSS) of ≥ 2. 69 participants were randomised to each treatment arm. 1 participant was excluded from the Honevo group, and 7 and 15 participants withdrew from the Honevo and control groups, respectively. INTERVENTIONS: Participants were randomly allocated 1:1 to Honevo or control cream (Cetomacrogol), applied twice daily for 8 weeks. MAIN OUTCOME MEASURES: The primary outcome measure was the proportion of participants who had a ≥ 2 improvement in the 7-point IGA-RSS at week 8 compared to baseline. Secondary outcomes included change in IGA-RSS and subject-rated visual analogue score of change in severity (VAS-CS) on a 100 mm scale (0 mm 'much worse', 100 mm 'much improved') at weeks 2 and 8. RESULTS: 24/68 (34.3%) in the Honevo group and 12/69 (17.4%) in the control group had a ≥ 2 improvement in IGA-RSS at week 8 compared to baseline (relative risk 2.03; 95% CI 1.11 to 3.72, p=0.020). The change in IGA-RSS for Honevo compared to control at week 2 minus baseline was -1 (Hodges-Lehman estimate, 95% CI -1 to 0, p=0.03), and at week 8 minus baseline was -1 (Hodges-Lehman estimate, 95% CI -1 to 0, p=0.005). The VAS-CS at week 2 was 9.1 (95% CI 3.5 to 14.7), p=0.002, and at week 8 was 12.3 (95% CI 5.7 to 18.9)¸ p<0.001 for Honevo compared to control. CONCLUSIONS: Honevo is an effective treatment for rosacea. TRIAL REGISTRATION NUMBER: This trial was registered in the Australian and New Zealand Clinical Trials Registry ACTRN12614000004662.
[Mh] Termos MeSH primário: Mel
Kunzea
Rosácea/terapia
[Mh] Termos MeSH secundário: Administração Cutânea
Idoso
Fármacos Dermatológicos/uso terapêutico
Glicerol/uso terapêutico
Seres Humanos
Meia-Idade
Índice de Gravidade de Doença
Creme para a Pele
Resultado do Tratamento
[Pt] Tipo de publicação:JOURNAL ARTICLE; RANDOMIZED CONTROLLED TRIAL; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Dermatologic Agents); PDC6A3C0OX (Glycerol)
[Em] Mês de entrada:1602
[Cu] Atualização por classe:160603
[Lr] Data última revisão:
160603
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:150626
[St] Status:MEDLINE
[do] DOI:10.1136/bmjopen-2015-007651


  5 / 20 MEDLINE  
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[PMID]:25368982
[Au] Autor:Gardner-Gee R; Dhami MK; Paulin KJ; Beggs JR
[Ad] Endereço:School of Biological Sciences, University of Auckland, Private Bag 92019, Auckland 1142, New Zealand.
[Ti] Título:Can alternative sugar sources buffer pollinators from nectar shortages?
[So] Source:Environ Entomol;43(6):1514-25, 2014 Dec.
[Is] ISSN:1938-2936
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Honeydew is abundant in many ecosystems and may provide an alternative food source (a buffer) for pollinators during periods of food shortage, but the impact of honeydew on pollination systems has received little attention to date. In New Zealand, kanuka trees (Myrtaceae: Kunzea ericoides (A. Rich) Joy Thompson) are often heavily infested by the endemic honeydew-producing scale insect Coelostomidia wairoensis (Maskell) (Hemiptera: Coelostomidiidae) and the period of high honeydew production can overlap with kanuka flowering. In this study, we quantified the sugar resources (honeydew and nectar) available on kanuka and recorded nocturnal insect activity on infested and uninfested kanuka during the flowering period. Insects were abundant on infested trees, but flowers on infested trees received fewer insect visitors than flowers on uninfested trees. There was little evidence that insects had switched directly from nectar-feeding to honeydew-feeding, but it is possible that some omnivores (e.g., cockroaches) were distracted by the other honeydew-associated resources on infested branches (e.g., sooty molds, prey). Additional sampling was carried out after kanuka flowering had finished to determine honeydew usage in the absence of adjacent nectar resources. Moths, which had fed almost exclusively on nectar earlier, were recorded feeding extensively on honeydew after flowering had ceased; hence, honeydew may provide an additional food source for potential pollinators. Our results show that honeydew resources can impact floral visitation patterns and suggest that future pollinator studies should consider the full range of sugar resources present in the study environment.
[Mh] Termos MeSH primário: Carboidratos/análise
Fezes/química
Comportamento Alimentar/fisiologia
Hemípteros/química
Insetos/fisiologia
Kunzea/química
Néctar de Plantas/química
[Mh] Termos MeSH secundário: Animais
Hemípteros/fisiologia
Interações Hospedeiro-Parasita/fisiologia
Kunzea/parasitologia
Nova Zelândia
Polinização/fisiologia
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Carbohydrates); 0 (Plant Nectar)
[Em] Mês de entrada:1508
[Cu] Atualização por classe:171116
[Lr] Data última revisão:
171116
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:141105
[St] Status:MEDLINE
[do] DOI:10.1603/EN13292


  6 / 20 MEDLINE  
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[PMID]:23418472
[Au] Autor:Lu J; Carter DA; Turnbull L; Rosendale D; Hedderley D; Stephens J; Gannabathula S; Steinhorn G; Schlothauer RC; Whitchurch CB; Harry EJ
[Ad] Endereço:The ithree institute, University of Technology Sydney, Sydney, Australia.
[Ti] Título:The effect of New Zealand kanuka, manuka and clover honeys on bacterial growth dynamics and cellular morphology varies according to the species.
[So] Source:PLoS One;8(2):e55898, 2013.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Treatment of chronic wounds is becoming increasingly difficult due to antibiotic resistance. Complex natural products with antimicrobial activity, such as honey, are now under the spotlight as alternative treatments to antibiotics. Several studies have shown honey to have broad-spectrum antibacterial activity at concentrations present in honey dressings, and resistance to honey has not been attainable in the laboratory. However not all honeys are the same and few studies have used honey that is well defined both in geographic and chemical terms. Here we have used a range of concentrations of clover honey and a suite of manuka and kanuka honeys from known geographical locations, and for which the floral source and concentration of methylglyoxal and hydrogen peroxide potential were defined, to determine their effect on growth and cellular morphology of four bacteria: Bacillus subtilis, Escherichia coli, Staphylococcus aureus and Pseudomonas aeruginosa. While the general trend in effectiveness of growth inhibition was manuka>manuka-kanuka blend>kanuka>clover, the honeys had varying and diverse effects on the growth and cellular morphology of each bacterium, and each organism had a unique response profile to these honeys. P. aeruginosa showed a markedly different pattern of growth inhibition to the other three organisms when treated with sub-inhibitory concentrations of honey, being equally sensitive to all honeys, including clover, and the least sensitive to honey overall. While hydrogen peroxide potential contributed to the antibacterial activity of the manuka and kanuka honeys, it was never essential for complete growth inhibition. Cell morphology analysis also showed a varied and diverse set of responses to the honeys that included cell length changes, cell lysis, and alterations to DNA appearance. These changes are likely to reflect the different regulatory circuits of the organisms that are activated by the stress of honey treatment.
[Mh] Termos MeSH primário: Antibacterianos/farmacologia
Bacillus subtilis/efeitos dos fármacos
Escherichia coli/efeitos dos fármacos
Mel
Pseudomonas aeruginosa/efeitos dos fármacos
Staphylococcus aureus/efeitos dos fármacos
[Mh] Termos MeSH secundário: Bacillus subtilis/crescimento & desenvolvimento
Escherichia coli/crescimento & desenvolvimento
Kunzea
Leptospermum
Medicago
Testes de Sensibilidade Microbiana
Nova Zelândia
Pseudomonas aeruginosa/crescimento & desenvolvimento
Staphylococcus aureus/crescimento & desenvolvimento
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Anti-Bacterial Agents)
[Em] Mês de entrada:1308
[Cu] Atualização por classe:170220
[Lr] Data última revisão:
170220
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:130219
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0055898


  7 / 20 MEDLINE  
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[PMID]:22814544
[Au] Autor:van Manen SM; Reeves R
[Ad] Endereço:GNS Science, Private Bag 2000, Taupo, 3352, New Zealand. saskia.vanmanen@open.ac.uk
[Ti] Título:An assessment of changes in Kunzea ericoides var. microflora and other hydrothermal vegetation at the Wairakei-Tauhara geothermal field, New Zealand.
[So] Source:Environ Manage;50(4):766-86, 2012 Oct.
[Is] ISSN:1432-1009
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Hydrothermal ecosystems are of high conservation and scientific value, but they are sensitive to external perturbations that result from development. This study examines the composition of vegetation at four plots at the Wairakei-Tauhara geothermal field, New Zealand, using the Scott height-frequency method, ground temperatures at 0.1- and 1-m depth, soil pH, and photographic surveys. It highlights the response of plant communities, in particular that of Kunzea ericoides var. microflora, in terms of composition, structure, and biomass index values, measures changes in ground temperature, as well as provides baseline data against which to compare future changes. It was found that optimal growing conditions for K. ericoides var. microflora are at temperatures above background conditions with a slightly acidic pH. Plots with cooler, less acidic conditions support more diverse plant communities, which also promote the establishment of invasive species. This suggests that the largest threats to thermotolerant vegetation in New Zealand, including K. ericoides var. microflora, are further decreases in ground temperature because the establishment of invasive species may result in thermolerant vegetation being out-competed in hydrothermal ecosystems. Recognising and understanding the ecological diversity and dynamics of hydrothermal ecosystems, as well as acknowledging the competing interests between development and conservation, is key to the management and protection of these areas.
[Mh] Termos MeSH primário: Conservação dos Recursos Naturais
Fontes Termais
Kunzea
[Mh] Termos MeSH secundário: Biomassa
Ecossistema
Monitoramento Ambiental
Concentração de Íons de Hidrogênio
Espécies Introduzidas
Nova Zelândia
Temperatura Ambiente
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Em] Mês de entrada:1211
[Cu] Atualização por classe:170924
[Lr] Data última revisão:
170924
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:120721
[St] Status:MEDLINE
[do] DOI:10.1007/s00267-012-9899-1


  8 / 20 MEDLINE  
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[PMID]:22385000
[Au] Autor:Holt S; Johnson K; Ryan J; Catchpole O; Zhang S; Mitchell KA
[Ti] Título:New Zealand kanuka honey has high levels of methylglyoxal and antimicrobial activity.
[So] Source:J Altern Complement Med;18(3):203-4, 2012 Mar.
[Is] ISSN:1557-7708
[Cp] País de publicação:United States
[La] Idioma:eng
[Mh] Termos MeSH primário: Antibacterianos/farmacologia
Antifúngicos/farmacologia
Apiterapia
Mel
Kunzea
Aldeído Pirúvico/farmacologia
[Mh] Termos MeSH secundário: Nova Zelândia
[Pt] Tipo de publicação:LETTER
[Nm] Nome de substância:
0 (Anti-Bacterial Agents); 0 (Antifungal Agents); 722KLD7415 (Pyruvaldehyde)
[Em] Mês de entrada:1207
[Cu] Atualização por classe:131121
[Lr] Data última revisão:
131121
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:120306
[St] Status:MEDLINE
[do] DOI:10.1089/acm.2011.0685


  9 / 20 MEDLINE  
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[PMID]:22212104
[Au] Autor:Gannabathula S; Skinner MA; Rosendale D; Greenwood JM; Mutukumira AN; Steinhorn G; Stephens J; Krissansen GW; Schlothauer RC
[Ad] Endereço:The New Zealand Institute for Plant & Food Research Limited, Mt Albert, Auckland, New Zealand. s.gannabathula@auckland.ac.nz
[Ti] Título:Arabinogalactan proteins contribute to the immunostimulatory properties of New Zealand honeys.
[So] Source:Immunopharmacol Immunotoxicol;34(4):598-607, 2012 Aug.
[Is] ISSN:1532-2513
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:CONTEXT: Factors in honey that improve wound healing are poorly understood, but are thought to include lipopolysaccharide (LPS), apalbumin-1 and -2, and a 5.8 kDa component that stimulate cytokine release from macrophages. OBJECTIVE: To characterize the ability of New Zealand honeys to elicit the release of tumor necrosis factor-α (TNF-α) from monocytic cell lines as a model for early events within a wound site. MATERIALS AND METHODS: The ability of kanuka (Kunzea ericoides), manuka (Leptospermum scoparium), and clover (Trifolium spp.) honeys to stimulate the release of TNF-α from monocytic cell lines THP-1 and U937 was assayed by ELISA. RESULTS: All three honeys stimulated TNF-α release from THP-1 cells, with kanuka honey being the most active. The activity of kanuka honey was associated with a high molecular weight (>30 kDa) component that was partially heat labile and inhibitable with polymyxin B. LPS concentrations in the honeys were too low to adequately explain the level of immunostimulation. The contribution of type II arabinogalactan proteins (AGPs) we recently identified in kanuka honey was tested, as AGPs are known immunostimulators. AGPs purified from kanuka honey stimulated the release of TNF-α from THP-1 and U937 cells. DISCUSSION: Here we demonstrated that AGPs we recently identified in kanuka honey have immunostimulatory activity. We propose that the immunostimulatory properties of individual honeys relate to their particular content of LPS, apalbumins, the 5.8 kDa component and AGPs. CONCLUSION: The immunostimulatory activity of kanuka honey may be particularly dependent on AGPs derived from the nectar of kanuka flowers.
[Mh] Termos MeSH primário: Mel
Fatores Imunológicos/farmacologia
Fator de Necrose Tumoral alfa/imunologia
[Mh] Termos MeSH secundário: Antibacterianos/farmacologia
Seres Humanos
Fatores Imunológicos/química
Kunzea/química
Leptospermum/química
Lipopolissacarídeos/farmacologia
Medicago/química
Nova Zelândia
Polimixina B/farmacologia
Fator de Necrose Tumoral alfa/metabolismo
Células U937
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Anti-Bacterial Agents); 0 (Immunologic Factors); 0 (Lipopolysaccharides); 0 (Tumor Necrosis Factor-alpha); 1404-26-8 (Polymyxin B)
[Em] Mês de entrada:1211
[Cu] Atualização por classe:120710
[Lr] Data última revisão:
120710
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:120104
[St] Status:MEDLINE
[do] DOI:10.3109/08923973.2011.641974


  10 / 20 MEDLINE  
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[PMID]:20148269
[Au] Autor:Page T; Moore GM; Will J; Halloran GM
[Ad] Endereço:Agroforestry and Novel Crops Unit, School of Marine and Tropical Biology, James Cook University, PO Box 6811, Cairns, QLD, 4870, Australia. tony.page@jcu.edu.au
[Ti] Título:Breeding behaviour of Kunzea pomifera (Myrtaceae): self-incompatibility, intraspecific and interspecific cross-compatibility.
[So] Source:Sex Plant Reprod;23(3):239-53, 2010 Sep.
[Is] ISSN:1432-2145
[Cp] País de publicação:Germany
[La] Idioma:eng
[Ab] Resumo:To examine breeding system characteristics of the endemic Australian prostrate shrub Kunzea pomifera, artificial hybridisations were undertaken using thirteen different genotypes of K. pomifera, to elucidate: (1) self-incompatibility, (2) intraspecific cross-compatibility in the species and (3) interspecific cross-compatibility with each of K. ambigua and K. ericoides. K. pomifera exhibited very low self-compatibility, with the barrier to self-fertilisation being prevention of pollen-tube growth in the style or ovary. Following intraspecific pollination amongst a number of different genotypes of K. pomifera, 38.4% of pollinated flowers developed fruit; arrest of compatible pollen-tubes in the style, preventing fertilisation, contributes to the low fruit set in this species. Interspecific compatibility was examined between K. pomifera (pistillate parent) and K. ambigua (staminate parent) where seed set per pollinated flower (4.47) was not significantly different from intraspecific crosses (4.66). In crosses between K. pomifera (pistillate parent) and K. ericoides as staminate plant, 0.037% of pollinated flowers produced fruit, with 0.0075 seeds per pollinated flower. Reproductive barriers between these two species were evident in the style of K. pomifera, where the growing tips of the K. ericoides pollen-tubes swelled and ceased to grow.
[Mh] Termos MeSH primário: Hibridização Genética
Endogamia
Kunzea/genética
[Mh] Termos MeSH secundário: Cruzamentos Genéticos
Frutas/genética
Frutas/crescimento & desenvolvimento
Genótipo
Kunzea/crescimento & desenvolvimento
Kunzea/fisiologia
Tubo Polínico/genética
Tubo Polínico/crescimento & desenvolvimento
Polinização
Sementes/genética
Sementes/crescimento & desenvolvimento
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Em] Mês de entrada:1012
[Cu] Atualização por classe:171010
[Lr] Data última revisão:
171010
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:100212
[St] Status:MEDLINE
[do] DOI:10.1007/s00497-010-0133-0



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