Base de dados : MEDLINE
Pesquisa : B01.650.940.800.575.912.250.786.416 [Categoria DeCS]
Referências encontradas : 55 [refinar]
Mostrando: 1 .. 10   no formato [Detalhado]

página 1 de 6 ir para página                

  1 / 55 MEDLINE  
              next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28454190
[Au] Autor:Piwowarski JP; Bobrowska-Korczak B; Stanislawska I; Bielecki W; Wrzesien R; Granica S; Krupa K; Kiss AK
[Ad] Endereço:Department of Pharmacognosy and Molecular Basis of Phytotherapy, Medical University of Warsaw, Poland.
[Ti] Título:Evaluation of the Effect of Epilobium angustifolium Aqueous Extract on LNCaP Cell Proliferation in In Vitro and In Vivo Models.
[So] Source:Planta Med;83(14-15):1159-1168, 2017 Oct.
[Is] ISSN:1439-0221
[Cp] País de publicação:Germany
[La] Idioma:eng
[Ab] Resumo:sp. are commonly used in traditional medicine in the treatment of early stages of benign prostatic hyperplasia and inflammation. It is suggested that a dominating constituent, oenothein B, is responsible for the extracts therapeutic effects. Several bioactivities were established for extracts and oenothein B in various models, but due to the questionable bioavailability of this dimeric macrocyclic ellagitannin, their significance in the effects remains unresolved. We have thus focused our attention on a complex comparative investigation of the and activities of phytochemically characterized aqueous extract and oenothein B on prostate cancer cells proliferation.Incubation of different cell lines with aqueous extract resulted in a significant reduction of proliferation of PZ-HPV-7 and LNCaP cells, which was partly associated with antiandrogenic activity. These effects were fully congruent with oenothein B, examined in parallel. Oral supplementation of rats implanted with LNCaP cells with aqueous extract 50-200 mg/kg b. w. resulted in a reduction of the occurrence of prostatic adenoma up to 13 %. Oenothein B was not detected in the urine and feces of the aqueous extract-treated group, however, conjugates of nasutins gut microbiota metabolites of ellagitannins were detected in the urine, while in human volunteers supplemented with tea, only urolithin conjugates were present.Despite observing significant and consistent effects and , we were unable to point out unequivocally the factors contributing to the observed aqueous extract activity, facing the problems of an unknown metabolic fate of oenothein B and interspecies differences in aqueous extract gut microbiota metabolism.
[Mh] Termos MeSH primário: Epilobium/química
Taninos Hidrolisáveis/farmacologia
Extratos Vegetais/farmacologia
Hiperplasia Prostática/tratamento farmacológico
Neoplasias da Próstata/tratamento farmacológico
[Mh] Termos MeSH secundário: Animais
Linhagem Celular Tumoral
Seres Humanos
Inflamação/tratamento farmacológico
Masculino
Medicina Tradicional
Extratos Vegetais/química
Extratos Vegetais/isolamento & purificação
Polifenóis/farmacologia
Ratos
Água
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Hydrolyzable Tannins); 0 (Plant Extracts); 0 (Polyphenols); 0 (ellagitannin); 059QF0KO0R (Water); 104987-36-2 (oenothein B)
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180201
[Lr] Data última revisão:
180201
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170429
[St] Status:MEDLINE
[do] DOI:10.1055/s-0043-109372


  2 / 55 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:27866749
[Au] Autor:Baert N; Kim J; Karonen M; Salminen JP
[Ad] Endereço:Laboratory of Organic Chemistry and Chemical Biology, Department of Chemistry, University of Turku, Turku, FI-20014, Finland. Electronic address: nicolas.baert@utu.fi.
[Ti] Título:Inter-population and inter-organ distribution of the main polyphenolic compounds of Epilobium angustifolium.
[So] Source:Phytochemistry;134:54-63, 2017 Feb.
[Is] ISSN:1873-3700
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Rosebay willowherb (Epilobium angustifolium) contains large amounts of polyphenolic compounds, including tellimagrandin I-based oligomeric ellagitannins (ETs). The aim of this study was to assess the interpopulational and inter-organ variability of the polyphenol fingerprint of E. angustifolium. Seven ETs, 11 flavonol glycosides and neochlorogenic acid were quantified by UHPLC-DAD-ESI-QqQ-MS in the leaves, flowers and stem parts of plants from 10 populations. Total polyphenol content of leaves and flowers ranged from 150 to 200 mg/g dry wt, of which 90% was constituted by dimeric to heptameric ETs. Flowers contained, on average, 10% more oenothein B (dimeric ET) and 2 times less oenothein A (trimeric ET) than leaves. Tetrameric and pentameric ETs exhibited rather similar levels in leaves and flowers whereas hexameric and heptameric were 3-4 times more abundant in flowers than in leaves. Quercetin-3-O-rhamnoside, myricetin-3-O-rhamnoside and kaempferol-3-O-rhamnoside were specific to flower tissue and were absent from leaves. The inflorescence stem showed the highest content in total polyphenols with an average of 250 mg/g dry wt and contained remarkably large amounts of oenothein B and A. Polyphenol content steadily decreased along the inflorescence stem and reached its lowest level in the vegetative part of the stem. The interpopulational variability of most polyphenols was within a two- to threefold range across the 10 sampled populations. Myricetin-3-O-glucoside and myricetin-3-O-glucuronide, however, showed a more population-specific distribution with concentrations varying from 0 to 2.3 mg/g dry wt. Finally, this study showed that the levels of oenothein B and A in the plant are not interdependent but that their relative abundance is constant within a population.
[Mh] Termos MeSH primário: Epilobium/química
Taninos Hidrolisáveis/química
Polifenóis
[Mh] Termos MeSH secundário: Flavonoides/análise
Flavonóis/análise
Ácido Gálico/análogos & derivados
Ácido Gálico/análise
Glucosídeos/análise
Glicosídeos/análise
Taninos Hidrolisáveis/análise
Taninos Hidrolisáveis/metabolismo
Quempferóis/análise
Manosídeos/análise
Onagraceae/química
Folhas de Planta/química
Polifenóis/análise
Polifenóis/química
Polifenóis/isolamento & purificação
Quercetina/análogos & derivados
Quercetina/análise
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Flavonoids); 0 (Flavonols); 0 (Glucosides); 0 (Glycosides); 0 (Hydrolyzable Tannins); 0 (Kaempferols); 0 (Mannosides); 0 (Polyphenols); 0 (kaempferol 3-O-rhamnoside); 0 (myricetin-3-O-rhamnoside); 104987-36-2 (oenothein B); 137422-98-1 (oenothein A); 2Y8906LC5P (quercitrin); 632XD903SP (Gallic Acid); 76XC01FTOJ (myricetin); 77363-65-6 (myricetin 3-O-glucuronide); 79786-08-6 (tellimagrandin I); 9IKM0I5T1E (Quercetin)
[Em] Mês de entrada:1703
[Cu] Atualização por classe:170306
[Lr] Data última revisão:
170306
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161122
[St] Status:MEDLINE


  3 / 55 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
[PMID]:27196503
[Au] Autor:Weedon CM
[Ad] Endereço:a Watercourse Systems Ltd , Taunton , Somerset , UK.
[Ti] Título:Tertiary sewage treatment by a full-scale compact vertical flow constructed wetland.
[So] Source:Environ Technol;38(2):140-153, 2017 Jan.
[Is] ISSN:0959-3330
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:A 208 m compact vertical flow treatment wetland (cVFTW) was studied, treating the rotating biological contactor (RBC) effluent of a busy UK visitor attraction, with widely varying daily sewage loads up to 111 resident population equivalent. Results are presented from monthly spot-sampling and analysis for inlet and outlet concentrations of BOD, SS, NH -N and TN, including load rates, for the first four-and-a-half years of operation. From commissioning to 13 weeks, outlet BOD, SS and NH -N were below 12 mg l , until a sudden outlet NH -N spike, to 31.9 mg l , the reasons for which are discussed. Thereafter, final effluent quality was <3:<3:<0.5 mg l BOD/SS/NH -N almost without exception, regardless of the determinand load rates imposed. Recirculation of controlled proportions of cVFTW effluent to the RBC inlet eliminated foul odour emanating from the RBC, and considerably increased overall nitrogen removal via denitrification. Phragmites australis development was poor, with the majority of plants experiencing chlorosis, putatively owing to insufficient bioavailable iron. By year three, despite ongoing weed removal to select for Phragmites, the wetland was increasingly colonised by other species, predominantly Epilobium hirsutum. Glyceria maxima, planted in year three, outcompeted even Epilobium, recommending itself as an alternative to Phragmites in high redox potential treatment wetlands.
[Mh] Termos MeSH primário: Eliminação de Resíduos Líquidos/métodos
Zonas Úmidas
[Mh] Termos MeSH secundário: Compostos de Amônio/metabolismo
Análise da Demanda Biológica de Oxigênio
Epilobium/crescimento & desenvolvimento
Epilobium/metabolismo
Nitrogênio/metabolismo
Odorantes
Poaceae/crescimento & desenvolvimento
Poaceae/metabolismo
Esgotos
Poluentes da Água/metabolismo
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Ammonium Compounds); 0 (Sewage); 0 (Water Pollutants); N762921K75 (Nitrogen)
[Em] Mês de entrada:1702
[Cu] Atualização por classe:170206
[Lr] Data última revisão:
170206
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160520
[St] Status:MEDLINE


  4 / 55 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:27246561
[Au] Autor:Ahmad A; Hadi F; Ali N; Jan AU
[Ad] Endereço:Department of Botany, University of Malakand, Chakdara, Dir Lower, Khyber Pakhtunkhwa, Pakistan.
[Ti] Título:Enhanced phytoremediation of cadmium polluted water through two aquatic plants Veronica anagallis-aquatica and Epilobium laxum.
[So] Source:Environ Sci Pollut Res Int;23(17):17715-29, 2016 Sep.
[Is] ISSN:1614-7499
[Cp] País de publicação:Germany
[La] Idioma:eng
[Ab] Resumo:Toxic metal-contaminated water is a major threat to sustainable agriculture and environment. Plants have the natural ability to absorb and concentrate essential elements in its tissues from water solution, and this ability of plants can be exploited to remove heavy/toxic metals from the contaminated water. For this purpose, two plants Veronica anagallis-aquatica and Epilobium laxum were hydroponically studied. The effect of different fertilizers (NPK) and plant growth regulators (GA3 and IAA) were evaluated on growth, biomass, free proline, phenolics, and chlorophyll contents, and their role in Cd phytoaccumulation was investigated. Results showed that in both plants, fertilizer addition to media (treatment T4) produced the highest significant increase in growth, biomass (fresh and dry), cadmium concentration, proline, phenolics, and chlorophyll concentrations. The significant effect of GA3 in combination with NPK foliar spray (treatment T12) was observed on most of the growth parameters, Cd concentration, and proline and phenolic contents of the plants. The free proline and total phenolics showed positive correlation with cadmium concentration within plant tissues. Proline showed significantly positive correlation with phenolic contents of root and shoot. Veronica plant demonstrated the hyperaccumulator potential for cadmium as bioconcentration factor (BCF >1) which was much higher than 1, while Epilobium plant showed non-hyperaccumulator potential. It is recommended for further study to investigate the role of Veronica plant for other metals and to study the role of phenolics and proline contents in heavy metal phytoextraction by various plant species.
[Mh] Termos MeSH primário: Biodegradação Ambiental
Cádmio/metabolismo
Epilobium/fisiologia
Veronica/fisiologia
Poluentes Químicos da Água/metabolismo
[Mh] Termos MeSH secundário: Anagallis
Biomassa
Cádmio/análise
Clorofila
Fertilizantes/análise
Metais Pesados/análise
Reguladores de Crescimento de Planta
Raízes de Plantas/química
Poluentes Químicos da Água/análise
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Fertilizers); 0 (Metals, Heavy); 0 (Plant Growth Regulators); 0 (Water Pollutants, Chemical); 00BH33GNGH (Cadmium); 1406-65-1 (Chlorophyll)
[Em] Mês de entrada:1704
[Cu] Atualização por classe:171103
[Lr] Data última revisão:
171103
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160602
[St] Status:MEDLINE
[do] DOI:10.1007/s11356-016-6960-2


  5 / 55 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:27215200
[Au] Autor:Schepetkin IA; Ramstead AG; Kirpotina LN; Voyich JM; Jutila MA; Quinn MT
[Ad] Endereço:Department of Microbiology and Immunology, Montana State University, Bozeman, MT, 59717, USA.
[Ti] Título:Therapeutic Potential of Polyphenols from Epilobium Angustifolium (Fireweed).
[So] Source:Phytother Res;30(8):1287-97, 2016 Aug.
[Is] ISSN:1099-1573
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Epilobium angustifolium is a medicinal plant used around the world in traditional medicine for the treatment of many disorders and ailments. Experimental studies have demonstrated that Epilobium extracts possess a broad range of pharmacological and therapeutic effects, including antioxidant, anti-proliferative, anti-inflammatory, antibacterial, and anti-aging properties. Flavonoids and ellagitannins, such as oenothein B, are among the compounds considered to be the primary biologically active components in Epilobium extracts. In this review, we focus on the biological properties and the potential clinical usefulness of oenothein B, flavonoids, and other polyphenols derived from E. angustifolium. Understanding the biochemical properties and therapeutic effects of polyphenols present in E. angustifolium extracts will benefit further development of therapeutic treatments from this plant. Copyright © 2016 John Wiley & Sons, Ltd.
[Mh] Termos MeSH primário: Epilobium/química
Extratos Vegetais/farmacologia
Plantas Medicinais/química
Polifenóis/química
[Mh] Termos MeSH secundário: Seres Humanos
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Nm] Nome de substância:
0 (Plant Extracts); 0 (Polyphenols)
[Em] Mês de entrada:1704
[Cu] Atualização por classe:170817
[Lr] Data última revisão:
170817
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160525
[St] Status:MEDLINE
[do] DOI:10.1002/ptr.5648


  6 / 55 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:26700224
[Au] Autor:Karakurt S; Semiz A; Celik G; Gencler-Ozkan AM; Sen A; Adali O
[Ad] Endereço:a Middle East Technical University, Department of Biological Sciences and Joint Graduate Program in Biochemistry, Ankara, Turkey, and Selcuk University, Faculty of Sciences, Department of Biochemistry , Konya , Turkey.
[Ti] Título:Contribution of ellagic acid on the antioxidant potential of medicinal plant Epilobium hirsutum.
[So] Source:Nutr Cancer;68(1):173-83, 2016.
[Is] ISSN:1532-7914
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:In the present study, the possible role of ellagic acid (EA) on antioxidant potential of Epilobium hirsutum (EH) in rat liver was investigated. Wistar rats were intraperitoneally treated with 37.5 mg/kg of EH and 10 mg/kg of EA for 9 days. Effects of EH and EA on antioxidant [glutathione peroxidase (GPx) and superoxide dismutases (SOD)] and Phase II [NADPH quinone oxidoreductase 1 (NQO1) and glutathione S-transferases (GSTs)] enzyme activities, as well as protein and mRNA expressions of those, were investigated. Polyphenolic content of EH was determined by LC-MS/MS analysis. EH and EA injection to rats resulted in a significant increase of NQO1 (3.6-fold and 4.7-fold), GPx (1.45-fold), and SOD (1.34-fold and 1.27-fold) enzyme activities, whereas total GST (46% and 57%) and its isoforms,and GST mu (57% and 72%), and GST theta (60% and 68%) activities were significantly decreased. Western-blot and qRT-PCR analysis showed that NQO1 and GPx protein and mRNA expressions were increased significantly (P < 0.0001), whereas GST mu and GST theta were significantly decreased (P < 0.0001).
[Mh] Termos MeSH primário: Antioxidantes/farmacologia
Ácido Elágico/farmacologia
Epilobium
[Mh] Termos MeSH secundário: Animais
Fígado/efeitos dos fármacos
Fígado/enzimologia
Masculino
NAD(P)H Desidrogenase (Quinona)/metabolismo
Plantas Medicinais
Ratos
Ratos Wistar
Superóxido Dismutase/metabolismo
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Antioxidants); 19YRN3ZS9P (Ellagic Acid); EC 1.15.1.1 (Superoxide Dismutase); EC 1.6.5.2 (NAD(P)H Dehydrogenase (Quinone)); EC 1.6.5.2 (NQO1 protein, rat)
[Em] Mês de entrada:1612
[Cu] Atualização por classe:161230
[Lr] Data última revisão:
161230
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:151225
[St] Status:MEDLINE
[do] DOI:10.1080/01635581.2016.1115092


  7 / 55 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:25425117
[Au] Autor:Celik G; Semiz A; Karakurt S; Gencler-Ozkan AM; Arslan S; Adali O; Sen A
[Ad] Endereço:Department of Biology, Pamukkale University, 20070, Kinikli-Denizli, Turkey.
[Ti] Título:Inhibitory action of Epilobium hirsutum extract and its constituent ellagic acid on drug-metabolizing enzymes.
[So] Source:Eur J Drug Metab Pharmacokinet;41(2):109-16, 2016 Apr.
[Is] ISSN:2107-0180
[Cp] País de publicação:France
[La] Idioma:eng
[Ab] Resumo:Epilobium hirsutum (EH) is a medicinal plant for treating various diseases. Despite its wide usage, there is no available information about its potential influences on drug metabolism. The present study was undertaken to determine the in vivo effects of EH on hepatic CYP2B, CYP2C, CYP2D, and CYP3A enzymes that are primarily involved in drug metabolism. Male Wistar rats were injected intraperitoneally with EH water extract (EHWE) and ellagic acid (EA) at a daily dose of 37.5 and 20 mg/kg, respectively, for 9 days and hepatic drug-metabolizing enzymes were assessed at activity, protein and mRNA levels. Erythromycin N-demethylase activity was inhibited by 53 and 21 % in EHWE- and EA-treated rats, respectively. Benzphetamine N-demethylase and 7-benzyloxyresorufin-O-debenzylase activities were decreased by 53 and 43 %, and 57 and 57 % in EHWE-and EA-treated rats, respectively. Moreover, protein levels of CYP2B1, CYP2C6, CYP2D2, and CYP3A1 also decreased by 55, 15, 33, and 82 % as a result of EHWE treatment of rats, respectively. Similarly, CYP2B1, CYP2C6, CYP2D2, and CYP3A1 protein levels decreased by 62, 63, 49, and 37 % with EA treatment, respectively. qRT-PCR analyses also showed that mRNA levels of these enzymes were significantly inhibited with bothEHWE and EA treatments. In conclusion, inhibition of drug clearances leading to drug toxicity because of the lowered activity and expression of drug-metabolizing enzymes might be observed in the people who used EH as complementary herbal remedy that might be contributed by its EA content.
[Mh] Termos MeSH primário: Sistema Enzimático do Citocromo P-450/metabolismo
Ácido Elágico/efeitos adversos
Ácido Elágico/farmacologia
Epilobium/efeitos adversos
Inativação Metabólica/efeitos dos fármacos
Extratos Vegetais/efeitos adversos
Extratos Vegetais/farmacologia
[Mh] Termos MeSH secundário: Animais
Masculino
Taxa de Depuração Metabólica/efeitos dos fármacos
Oxirredutases N-Desmetilantes/metabolismo
Plantas Medicinais/efeitos adversos
Ratos
Ratos Wistar
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Plant Extracts); 19YRN3ZS9P (Ellagic Acid); 9035-51-2 (Cytochrome P-450 Enzyme System); EC 1.14.14.1 (benzphetamine N-demethylase); EC 1.5.- (Oxidoreductases, N-Demethylating)
[Em] Mês de entrada:1612
[Cu] Atualização por classe:171111
[Lr] Data última revisão:
171111
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:141127
[St] Status:MEDLINE
[do] DOI:10.1007/s13318-014-0238-1


  8 / 55 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:26455285
[Au] Autor:Baert N; Karonen M; Salminen JP
[Ad] Endereço:Laboratory of Organic Chemistry and Chemical Biology, Department of Chemistry, University of Turku, Turku FI-20014, Finland. Electronic address: nicolas.baert@utu.fi.
[Ti] Título:Isolation, characterisation and quantification of the main oligomeric macrocyclic ellagitannins in Epilobium angustifolium by ultra-high performance chromatography with diode array detection and electrospray tandem mass spectrometry.
[So] Source:J Chromatogr A;1419:26-36, 2015 Nov 06.
[Is] ISSN:1873-3778
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:Tannins have beneficial effects in animal nutrition as they are able to decrease methane emission in ruminants and exert anthelminthic activity against intestinal nematodes. However, tannins can have very diverse structures and therefore, different activities. In order to enhance the research in tannin-rich forages we need tools which are able to quantify tannins individually. In this study we isolated and characterised the main tellimagrandin I (TI)-based oligomeric ellagitannins (ETs) from Epilobium angustifolium (willowherb) and developed a UHPLC-DAD-ESI-MS/MS method to quantify them in plant extracts. The mass spectrometer was operated in Multiple Reaction Monitoring mode to enable the selective detection of dimeric to heptameric ETs from the plant extract. The method proved to be sensitive, with limits of detection ranging from 0.1 to 1.3µgmL(-1). The stability test showed a good repeatability with an inter-run deviation of the results from 0.1 to 5%, except for the pentamer and hexamer where it reached 8%. The method was then successfully applied to evaluate the distribution of those ETs in the plant. This work also provides the first time evidence of the presence of tetrameric to heptameric TI in willowherb.
[Mh] Termos MeSH primário: Epilobium/química
Taninos Hidrolisáveis/análise
Extratos Vegetais/química
[Mh] Termos MeSH secundário: Cromatografia Líquida de Alta Pressão/métodos
Espectrometria de Massas em Tandem/métodos
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Hydrolyzable Tannins); 0 (Plant Extracts)
[Em] Mês de entrada:1605
[Cu] Atualização por classe:151019
[Lr] Data última revisão:
151019
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:151013
[St] Status:MEDLINE


  9 / 55 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:26211750
[Au] Autor:Süle K; Kurucz D; Kajári Á; May Z
[Ad] Endereço:Farmakognóziai Intézet, Semmelweis Egyetem, Általános Orvostudományi Kar Budapest.
[Ti] Título:[Investigation of metal element content of some European and Far Eastern herbs].
[Ti] Título:Európai és távol-keleti gyógynövények és kivonatok fémelemtartalom-vizsgálata..
[So] Source:Orv Hetil;156(31):1261-9, 2015 Aug 02.
[Is] ISSN:0030-6002
[Cp] País de publicação:Hungary
[La] Idioma:hun
[Ab] Resumo:INTRODUCTION: Metal elements and their excess intake have significant influence on general health. AIM: There is only little information how Far Eastern herbs resemble European's regarding their purity and essential metal element content. The aim of the authors was to determine metal elements in different Chinese and European herbs and extracts. METHOD: The studied European herbs included Calendula officinalis petals, Achillea millefolium, Epilobium parviflorum herba, Urtica dioica leaves, Crataegus monogyna flowers while Far Eastern herbs were Cordyceps sinensis, Ganoderma lucidum, Ginkgo biloba leaves, Panax ginseng and Curcuma longa roots. The analysis was performed using inductively coupled plasma optical emission spectroscopy. RESULTS: There was no considerable difference in essential metal elements and the Ca:Mg concentration ratio between European and Far Eastern drugs and extracts. CONCLUSIONS: The extracts are preferential metal element sources and their magnesium content are also advantageous, because of a shift of the Ca:Mg concentration ratio towards magnesium.
[Mh] Termos MeSH primário: Metais/análise
Extratos Vegetais/química
Plantas Medicinais/química
Oligoelementos/análise
[Mh] Termos MeSH secundário: Achillea/química
Cálcio/análise
Calendula/química
Cordyceps/química
Crataegus/química
Curcuma/química
Epilobium/química
Europa (Continente)
Extremo Oriente
Essências Florais/química
Ginkgo biloba/química
Magnésio/análise
Panax/química
Folhas de Planta/química
Raízes de Plantas/química
Reishi/química
Urtica dioica/química
[Pt] Tipo de publicação:ENGLISH ABSTRACT; JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Flower Essences); 0 (Metals); 0 (Plant Extracts); 0 (Trace Elements); I38ZP9992A (Magnesium); SY7Q814VUP (Calcium)
[Em] Mês de entrada:1511
[Cu] Atualização por classe:150727
[Lr] Data última revisão:
150727
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:150728
[St] Status:MEDLINE
[do] DOI:10.1556/650.2015.30193


  10 / 55 MEDLINE  
              first record previous record
seleciona
para imprimir
Fotocópia
PubMed Central Texto completo
Texto completo
[PMID]:25887271
[Au] Autor:Ramstead AG; Schepetkin IA; Todd K; Loeffelholz J; Berardinelli JG; Quinn MT; Jutila MA
[Ad] Endereço:Department of Microbiology and Immunology, Montana State University, Bozeman, MT 59717, United States.
[Ti] Título:Aging influences the response of T cells to stimulation by the ellagitannin, oenothein B.
[So] Source:Int Immunopharmacol;26(2):367-77, 2015 Jun.
[Is] ISSN:1878-1705
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:Several plant extracts, including certain polyphenols, prime innate lymphocytes and enhance responses to secondary stimuli. Oenothein B, a polyphenol isolated from Epilobium angustifolium and other plant sources, enhances IFNγ production by both bovine and human NK cells and T cells, alone and in response to secondary stimulation by cytokines or tumor cells. Innate immune cell responsiveness is known to be affected by aging, but whether polyphenol responses by these cells are also impacted by aging is not known. Therefore, we examined oenothein B responsiveness in T cells from cord blood, young, and adult donors. We found that oenothein B stimulates bovine and human T cells from individuals over a broad range of ages, as measured by increased IL-2Rα and CD69 expression. However, clear differences in induction of cytokine production by T cells were seen. In T cells from human cord blood and bovine calves, oenothein B was unable to induce IFNγ production. However, oenothein B induced IFNγ production by T cells from adult humans and cattle. In addition, oenothein B induced GM-CSF production by human adult T cells, but not cord blood T cells. Within the responsive T cell population, we found that CD45RO+ memory T cells expressed more cytokines in response to oenothein B than CD45RO- T cells. In summary, our data suggest that the immunostimulation of T cells by oenothein B is influenced by age, particularly with respect to immune cytokine production.
[Mh] Termos MeSH primário: Envelhecimento/efeitos dos fármacos
Epilobium/imunologia
Taninos Hidrolisáveis/farmacologia
Células Matadoras Naturais/efeitos dos fármacos
Linfócitos T/efeitos dos fármacos
[Mh] Termos MeSH secundário: Adulto
Envelhecimento/imunologia
Animais
Antígenos CD/metabolismo
Antígenos de Diferenciação de Linfócitos T/metabolismo
Bovinos
Sangue Fetal/efeitos dos fármacos
Sangue Fetal/imunologia
Seres Humanos
Imunidade Celular/efeitos dos fármacos
Memória Imunológica/efeitos dos fármacos
Recém-Nascido
Interferon gama/metabolismo
Subunidade alfa de Receptor de Interleucina-2/metabolismo
Células Matadoras Naturais/imunologia
Lectinas Tipo C/metabolismo
Linfócitos T/imunologia
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, N.I.H., EXTRAMURAL; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Antigens, CD); 0 (Antigens, Differentiation, T-Lymphocyte); 0 (CD69 antigen); 0 (Hydrolyzable Tannins); 0 (Interleukin-2 Receptor alpha Subunit); 0 (Lectins, C-Type); 0 (ellagitannin); 104987-36-2 (oenothein B); 82115-62-6 (Interferon-gamma)
[Em] Mês de entrada:1602
[Cu] Atualização por classe:161019
[Lr] Data última revisão:
161019
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:150419
[St] Status:MEDLINE



página 1 de 6 ir para página                
   


Refinar a pesquisa
  Base de dados : MEDLINE Formulário avançado   

    Pesquisar no campo  
1  
2
3
 
           



Search engine: iAH v2.6 powered by WWWISIS

BIREME/OPAS/OMS - Centro Latino-Americano e do Caribe de Informação em Ciências da Saúde