Base de dados : MEDLINE
Pesquisa : B01.650.940.800.575.912.250.822.755 [Categoria DeCS]
Referências encontradas : 304 [refinar]
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[PMID]:28922347
[Au] Autor:Varshney RK; Shi C; Thudi M; Mariac C; Wallace J; Qi P; Zhang H; Zhao Y; Wang X; Rathore A; Srivastava RK; Chitikineni A; Fan G; Bajaj P; Punnuri S; Gupta SK; Wang H; Jiang Y; Couderc M; Katta MAVSK; Paudel DR; Mungra KD; Chen W; Harris-Shultz KR; Garg V; Desai N; Doddamani D; Kane NA; Conner JA; Ghatak A; Chaturvedi P; Subramaniam S; Yadav OP; Berthouly-Salazar C; Hamidou F; Wang J; Liang X; Clotault J; Upadhyaya HD; Cubry P; Rhoné B; Gueye MC; Sunkar R; Dupuy C; Sparvoli F; Cheng S; Mahala RS; Singh B; Yadav RS; Lyons E
[Ad] Endereço:International Crops Research Institute for the Semi-Arid Tropics (ICRISAT), Hyderabad, Telangana State, India.
[Ti] Título:Pearl millet genome sequence provides a resource to improve agronomic traits in arid environments.
[So] Source:Nat Biotechnol;35(10):969-976, 2017 Oct.
[Is] ISSN:1546-1696
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Pearl millet [Cenchrus americanus (L.) Morrone] is a staple food for more than 90 million farmers in arid and semi-arid regions of sub-Saharan Africa, India and South Asia. We report the ∼1.79 Gb draft whole genome sequence of reference genotype Tift 23D B -P1-P5, which contains an estimated 38,579 genes. We highlight the substantial enrichment for wax biosynthesis genes, which may contribute to heat and drought tolerance in this crop. We resequenced and analyzed 994 pearl millet lines, enabling insights into population structure, genetic diversity and domestication. We use these resequencing data to establish marker trait associations for genomic selection, to define heterotic pools, and to predict hybrid performance. We believe that these resources should empower researchers and breeders to improve this important staple crop.
[Mh] Termos MeSH primário: Agricultura
Clima Desértico
Genoma de Planta
Pennisetum/genética
Característica Quantitativa Herdável
[Mh] Termos MeSH secundário: Sequência de Bases
Sequência Conservada
Genes de Plantas
Variação Genética
Estudo de Associação Genômica Ampla
Hibridização Genética
Anotação de Sequência Molecular
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171023
[Lr] Data última revisão:
171023
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170919
[St] Status:MEDLINE
[do] DOI:10.1038/nbt.3943


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[PMID]:28869121
[Au] Autor:Yang M; Wang J; Hou X; Wu J; Fan X; Jiang F; Tao P; Wang F; Peng P; Yang F; Zhang J
[Ad] Endereço:College of Forestry, Northwest A&F University, 3 Taicheng Road, Yangling 712100, China.
[Ti] Título:Exploring surface characterization and electrostatic property of Hybrid Pennisetum during alkaline sulfite pretreatment for enhanced enzymatic hydrolysability.
[So] Source:Bioresour Technol;244(Pt 1):1166-1172, 2017 Nov.
[Is] ISSN:1873-2976
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:The surface characterization and electrostatic property of Hybrid Pennisetum (HP) after alkaline sulfite pretreatment were explored for enhanced enzymatic hydrolysability. The O/C ratio in HP increased from 0.34 to 0.60, and C1 concentration decreased from 62.5% to 31.6%, indicating that alkaline sulfite pretreatment caused poorer lignin but richer carbohydrate on HP surface. Zeta potential and sulfur element analysis indicated that more enzymes would preferably adsorb on the carbohydrate surface of alkaline sulfite pretreated HP because the lignin was sulfonated, which facilitated the decrease of non-productive adsorption. Glucose yield of alkaline sulfite pretreated HP reached to 100% by synergistic action of cellulase and xylanase in the hydrolysis, which was significantly higher than that of NaOH pretreated, and the concentration of glucose released was 1.52times higher. The results suggested that alkaline sulfite pretreatment had potential for improving the HP hydrolysability, and the surface characterization and electrostatic property facilitated the enzymatic digestibility.
[Mh] Termos MeSH primário: Pennisetum
Sulfitos
[Mh] Termos MeSH secundário: Celulase
Hidrólise
Lignina
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Sulfites); 9005-53-2 (Lignin); EC 3.2.1.4 (Cellulase)
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171023
[Lr] Data última revisão:
171023
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170905
[St] Status:MEDLINE


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[PMID]:28683386
[Au] Autor:Wang S; Chen J; Yang G; Gao W; Chen K
[Ad] Endereço:State Key Laboratory of Pulp and Paper Engineering, Plant Micro/Nano Fiber Research Center, South China University of Technology, Guangzhou 510640, China.
[Ti] Título:Efficient conversion of Hubrid Pennisetum to glucose by oxygen-aqueous alkaline ionic liquid media pretreatment under benign conditions.
[So] Source:Bioresour Technol;243:335-338, 2017 Nov.
[Is] ISSN:1873-2976
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:To enhance the cellulose digestibility of energy grass hybrid Pennisetum (P. americanum×P. purpureum, HP) with low energy-consumption and high efficiency, a novel combinatorial pretreatment of oxygen-aqueous alkaline ionic liquid (IL) 1-ethyl-3-methylimidazolium acetate ([Emim]Ac) media (OEA) was developed in this work. The combinatorial pretreatment was performed under the relatively low temperature (120°C), short retention time (30min), and 12bar oxygen pressure. The combinatorial pretreatment of OEA was demonstrated effectively for pretreatment of hybrid Pennisetum, which evidenced by the removal of lignin, degradation of carbohydrate, and porosity property of the regenerated biomass. Subsequently, a higher glucose recovery (96.9%) at a low enzyme loading (20FPU/g substrate) was obtained by the OEA pretreatment, and it was 9.1 times as much as the untreated samples. Overall, the novel OEA combinatorial pretreatment has the advantages of low thermal energy input and enzyme usage, and short retention time.
[Mh] Termos MeSH primário: Glucose
Oxigênio
Pennisetum
[Mh] Termos MeSH secundário: Celulase
Hidrólise
Líquidos Iônicos
Lignina
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Ionic Liquids); 9005-53-2 (Lignin); EC 3.2.1.4 (Cellulase); IY9XDZ35W2 (Glucose); S88TT14065 (Oxygen)
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171023
[Lr] Data última revisão:
171023
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170707
[St] Status:MEDLINE


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[PMID]:28637158
[Au] Autor:Li L; Yuan Z; Sun Y; Kong X; Dong P; Zhang J
[Ad] Endereço:Guangzhou Institute of Energy Conversion, CAS Key Laboratory of Renewable Energy, Chinese Academy of Sciences, Guangzhou 510640, PR China; University of Chinese Academy of Sciences, Beijing 100049, PR China; Guangdong Key Laboratory of New and Renewable Energy Research and Development, Guangzhou 510
[Ti] Título:A reused method for molasses-processed wastewater: Effect on silage quality and anaerobic digestion performance of Pennisetum purpereum.
[So] Source:Bioresour Technol;241:1003-1011, 2017 Oct.
[Is] ISSN:1873-2976
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:The silage quality and anaerobic digestion performance of Pennisetum purpereum with molasses-processed wastewater addition were assessed. The silage samples with molasses-processed wastewater addition obtained higher lactic acid concentration of 15.18-23.38mg/g FM, lower pH value of 3.96-4.45 and lower NH -N content of 0.47-0.64mg/g FM. No obvious difference was observed in the dominant phyla and genus, but the relative abundance of Lactobacillus reached up to 77.39%, increased by 84% compared to the silage samples without molasses-processed wastewater addition. Combined the silage quality and bacterial community, the decreased in pH value of fresh material caused by molasses-processed wastewater addition was the main reason for improving the silage quality. Meanwhile, the increased in COD concentration is beneficial for improving the specific methane yield and the maximum specific methane yield of 259±5.75mL/g VS was obtained with adding 20g/kg molasses-alcoholic wastewater. Molasses-processed wastewater is an alternative additive for silage.
[Mh] Termos MeSH primário: Melaço
Silagem
Águas Residuais
[Mh] Termos MeSH secundário: Fermentação
Pennisetum
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Waste Water)
[Em] Mês de entrada:1711
[Cu] Atualização por classe:171106
[Lr] Data última revisão:
171106
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170623
[St] Status:MEDLINE


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[PMID]:28525719
[Au] Autor:Mao X; Lu Q; Mo W; Xin X; Chen X; He Z
[Ad] Endereço:College of Natural Resources and Environment, South China Agricultural University , Guangzhou 510642, China.
[Ti] Título:Phosphorus Availability and Release Pattern from Activated Dolomite Phosphate Rock in Central Florida.
[So] Source:J Agric Food Chem;65(23):4589-4596, 2017 Jun 14.
[Is] ISSN:1520-5118
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:In this study, novel technology was developed to convert dolomite phosphate rock (DPR) into slow release P fertilizers. The DPR was powdered to <100 mesh and activated with organic molecules under optimal reaction conditions. As compared to original DPR, available P, estimated by water-soluble P released from the three DPRs activated with three types of organic molecules, increased by 6.86, 3.32, and 7.46 times, respectively. Phosphorus supply from the activated DPRs was greater than that of superphosphates (SP). Use of activated DPRs resulted in a significant increase in plant biomass of maize (Zea mays) and millet (Pennisetum glaucum) (succeeding crop), as compared to original DPR, and displayed better effectiveness than monoammonium phosphate or SP. The XRD and FTIR analyses showed that activation did not change the crystal structure of DPR, but the interactions between organic molecules and the P-bearing minerals stimulated P release from DPR.
[Mh] Termos MeSH primário: Carbonato de Cálcio/química
Sedimentos Geológicos/química
Magnésio/química
Fosfatos/química
Fósforo/química
[Mh] Termos MeSH secundário: Biomassa
Carbonato de Cálcio/metabolismo
Fertilizantes/análise
Florida
Cinética
Magnésio/metabolismo
Pennisetum/crescimento & desenvolvimento
Pennisetum/metabolismo
Fosfatos/metabolismo
Fósforo/metabolismo
Zea mays/crescimento & desenvolvimento
Zea mays/metabolismo
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Fertilizers); 0 (Phosphates); 27YLU75U4W (Phosphorus); H0G9379FGK (Calcium Carbonate); I38ZP9992A (Magnesium); UG9H2002BF (calcium magnesium carbonate)
[Em] Mês de entrada:1706
[Cu] Atualização por classe:170626
[Lr] Data última revisão:
170626
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170520
[St] Status:MEDLINE
[do] DOI:10.1021/acs.jafc.7b01037


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[PMID]:28490067
[Au] Autor:Adebiyi JA; Obadina AO; Adebo OA; Kayitesi E
[Ad] Endereço:Department of Biotechnology and Food Technology, Faculty of Science, University of Johannesburg, P. O. Box 17011, Doornfontein Campus, Gauteng, South Africa. Electronic address: janet.adeyinka@yahoo.com.
[Ti] Título:Comparison of nutritional quality and sensory acceptability of biscuits obtained from native, fermented, and malted pearl millet (Pennisetum glaucum) flour.
[So] Source:Food Chem;232:210-217, 2017 Oct 01.
[Is] ISSN:0308-8146
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:The effects of fermentation and malting on the proximate composition, mineral content, amino acids and total phenolic content of pearl millet flour and biscuits were studied. Consumer tests of the biscuits samples were also done using two sets of panelists. The results showed that fermentation and malting improved the crude fiber, crude protein, carbohydrate and energy values of the pearl millet flour. For the biscuit samples, the fermented and malted biscuits had higher moisture, crude protein, crude fiber and energy value with lower fat and ash content as compared to the biscuits obtained from native flour. Fermentation and malting were further observed to increase majority of the essential and non-essential amino acids. Consumer tests among the different set of panelists showed differences in the loading patterns as observed through principal component analysis. In conclusion, this study shows that fermentation and malting improves nutritional, health composition of pearl millet flour as well as the sensorial acceptability of subsequent biscuits.
[Mh] Termos MeSH primário: Farinha
Pennisetum
[Mh] Termos MeSH secundário: Proteínas na Dieta
Fermentação
Manipulação de Alimentos
Valor Nutritivo
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Dietary Proteins)
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170816
[Lr] Data última revisão:
170816
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170512
[St] Status:MEDLINE


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[PMID]:28415525
[Au] Autor:Revati R; Abdul Majid MS; Ridzuan MJM; Normahira M; Mohd Nasir NF; Rahman Y MN; Gibson AG
[Ad] Endereço:School of Mechatronic Engineering, Universiti Malaysia Perlis (UniMAP), Pauh Putra Campus, 02600 Arau, Perlis, Malaysia.
[Ti] Título:Mechanical, thermal and morphological characterisation of 3D porous Pennisetum purpureum/PLA biocomposites scaffold.
[So] Source:Mater Sci Eng C Mater Biol Appl;75:752-759, 2017 Jun 01.
[Is] ISSN:1873-0191
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:The mechanical, thermal, and morphological properties of a 3D porous Pennisetum purpureum (PP)/polylactic acid (PLA) based scaffold were investigated. In this study, a scaffold containing P. purpureum and PLA was produced using the solvent casting and particulate leaching method. P. purpureum fibre, also locally known as Napier grass, is composed of 46% cellulose, 34% hemicellulose, and 20% lignin. PLA composites with various P. purpureum contents (10%, 20%, and 30%) were prepared and subsequently characterised. The morphologies, structures and thermal behaviours of the prepared composite scaffolds were characterised using field-emission scanning electron microscopy (FESEM), Fourier transform infrared spectroscopy (FTIR), and thermogravimetric analysis (TGA). The morphology was studied using FESEM; the scaffold possessed 70-200µm-sized pores with a high level of interconnectivity. The moisture content and mechanical properties of the developed porous scaffolds were further characterised. The P. purpureum/PLA scaffold had a greater porosity factor (99%) and compression modulus (5.25MPa) than those of the pure PLA scaffold (1.73MPa). From the results, it can be concluded that the properties of the highly porous P. purpureum/PLA scaffold developed in this study can be controlled and optimised. This can be used to facilitate the construction of implantable tissue-engineered cartilage.
[Mh] Termos MeSH primário: Materiais Biocompatíveis/química
Pennisetum/química
Poliésteres/química
Tecidos Suporte/química
[Mh] Termos MeSH secundário: Força Compressiva
Teste de Materiais
Porosidade
Espectroscopia de Infravermelho com Transformada de Fourier
Termogravimetria
Engenharia Tecidual/métodos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Biocompatible Materials); 0 (Polyesters); 459TN2L5F5 (poly(lactide))
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170906
[Lr] Data última revisão:
170906
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170419
[St] Status:MEDLINE


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[PMID]:28337571
[Au] Autor:Albores-Moreno S; Alayón-Gamboa JA; Ayala-Burgos AJ; Solorio-Sánchez FJ; Aguilar-Pérez CF; Olivera-Castillo L; Ku-Vera JC
[Ad] Endereço:Facultad de Medicina Veterinaria y Zootecnia, Universidad Autónoma de Yucatán, C.P. 97300, Mérida, Yucatán, Mexico.
[Ti] Título:Effects of feeding ground pods of Enterolobium cyclocarpum Jacq. Griseb on dry matter intake, rumen fermentation, and enteric methane production by Pelibuey sheep fed tropical grass.
[So] Source:Trop Anim Health Prod;49(4):857-866, 2017 Apr.
[Is] ISSN:1573-7438
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:An experiment was carried out to determine the effect of supplementing ground pods of Enterolobium cyclocarpum in a basal ration of Pennisetum purpureum grass on feed intake, rumen volatile fatty acids (VFAs), and protozoa and methane (CH ) production by hair sheep. Four male sheep (Pelibuey × Katahdin) with a mean live weight of 27.0 kg (SD ± 0.5) were supplemented with 0.00, 0.15, 0.30, and 0.45 kg of dry matter (DM) of E. cyclocarpum pods daily; equivalent to 0.00, 4.35, 8.70, and 13.05 g of crude saponins, respectively. Dry matter intake (DMI), organic matter intake (OMI), and molar proportions of propionic acid increased linearly (P < 0.05) as pods of E. cyclocarpum in the ration were increased. Higher intakes of DM and OM were found when lambs were fed 0.45 kg DM per day of E. cyclocarpum, and the highest proportion of propionic acid (0.21 and 0.22, respectively) was obtained with 0.15 and 0.30 kg of DM per lamb of E. cyclocarpum, while apparent digestibility of neutral detergent fiber (NDF) and molar proportion of acetic acid were reduced (P < 0.05). Rumen CH production decreased (P < 0.05) when 0.30 and 0.45 kg of DM/lamb/day of E. cyclocarpum were fed (21.8 and 25.3 L CH /lamb/day, respectively). These results suggest that to improve the feeding of sheep fed tropical grass, it is advisable to supplement the basal ration with up to 0.30 kg DM of E. cyclocarpum pods.
[Mh] Termos MeSH primário: Digestão/efeitos dos fármacos
Fabaceae
Fermentação/efeitos dos fármacos
Metano/metabolismo
Saponinas/administração & dosagem
[Mh] Termos MeSH secundário: Ração Animal/análise
Animais
Fibras na Dieta
Suplementos Nutricionais
Ingestão de Alimentos
Ácidos Graxos Voláteis/metabolismo
Masculino
Pennisetum
Rúmen/metabolismo
Rúmen/parasitologia
Saponinas/metabolismo
Ovinos
Carneiro Doméstico
[Pt] Tipo de publicação:EVALUATION STUDIES; JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Dietary Fiber); 0 (Fatty Acids, Volatile); 0 (Saponins); OP0UW79H66 (Methane)
[Em] Mês de entrada:1706
[Cu] Atualização por classe:171116
[Lr] Data última revisão:
171116
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170325
[St] Status:MEDLINE
[do] DOI:10.1007/s11250-017-1275-y


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[PMID]:28295033
[Au] Autor:Ousseini IS; Bakasso Y; Kane NA; Couderc M; Zekraoui L; Mariac C; Manicacci D; Rhoné B; Barnaud A; Berthouly-Salazar C; Assoumane A; Moussa D; Moussa T; Vigouroux Y
[Ad] Endereço:Institut de Recherche pour le Développement, Montpellier, France.
[Ti] Título:Myosin XI is associated with fitness and adaptation to aridity in wild pearl millet.
[So] Source:Heredity (Edinb);119(2):88-94, 2017 Aug.
[Is] ISSN:1365-2540
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Phenotypic changes in plants can be observed along many environmental gradients and are determined by both environmental and genetic factors. The identification of alleles associated with phenotypic variations is a rapidly developing area of research. We studied the genetic basis of phenotypic variations in 11 populations of wild pearl millet (Pennisetum glaucum) on two North-South aridity gradients, one in Niger and one in Mali. Most of the 11 phenotypic traits assessed in a common garden experiment varied between the populations studied. Moreover, the size of the inflorescence, the number of flowers and aboveground dry mass co-varied positively with a decrease in rainfall. To decipher the genetic basis of these phenotypes, we used an association mapping strategy with a mixed model. We found two SNPs on the same myosin XI contig significantly associated with variations in the average number of flowers. Both the allele frequency of the two SNPs and the average number of flowers co-varied with the rainfall gradient on the two gradients. Interestingly, this gene was also a target of selection during domestication. The Myosin XI gene is thus a good candidate for fitness-related adaptation in wild populations.
[Mh] Termos MeSH primário: Adaptação Fisiológica/genética
Aptidão Genética
Miosinas/genética
Pennisetum/genética
[Mh] Termos MeSH secundário: Alelos
Clima
Frequência do Gene
Estudos de Associação Genética
Genética Populacional
Genótipo
Mali
Níger
Pennisetum/fisiologia
Fenótipo
Proteínas de Plantas/genética
Polimorfismo de Nucleotídeo Único
Chuvas
Água/fisiologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Plant Proteins); 059QF0KO0R (Water); EC 3.6.4.1 (Myosins)
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170803
[Lr] Data última revisão:
170803
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170316
[St] Status:MEDLINE
[do] DOI:10.1038/hdy.2017.13


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[PMID]:28238020
[Au] Autor:Conner JA; Podio M; Ozias-Akins P
[Ad] Endereço:Department of Horticulture, University of Georgia, Tifton Campus, Tifton, GA, 31793, USA. jconner@uga.edu.
[Ti] Título:Haploid embryo production in rice and maize induced by PsASGR-BBML transgenes.
[So] Source:Plant Reprod;30(1):41-52, 2017 Mar.
[Is] ISSN:2194-7961
[Cp] País de publicação:Germany
[La] Idioma:eng
[Ab] Resumo:KEY MESSAGE: The PsASGR - BBML transgene, derived from a wild apomictic grass species, can induce parthenogenesis, embryo formation without fertilization, in rice and maize, leading to the formation of haploid plants. The ability to engineer apomictic crop plants using genes identified from naturally occurring apomicts will depend on the ability of those genes to function in crop plants. The PsASGR-BBML transgene, derived from the apomictic species Pennisetum squamulatum, promotes parthenogenesis in sexual pearl millet, a member of the same genus, leading to the formation of haploid embryos. This study determined that the PsASGR-BBML transgene can induce haploid embryo development in two major monocot crops, maize and rice. Transgene variations tested included two different promoters and the use of both genomic and cDNA PsASGR-BBML-derived sequences. Haploid plants were recovered from mature caryopses (seed) of rice and maize lines at variable rates. The PsASGR-BBML transgenes failed to induce measurable haploid seed development in the model genetic plant system Arabidopsis thaliana. Complexity of embryo development, as documented in transgenic rice lines, identifies the need for further characterization of the PsASGR-BBML gene.
[Mh] Termos MeSH primário: Genes de Plantas
Haploidia
Oryza/embriologia
Oryza/genética
Transgenes
Zea mays/embriologia
Zea mays/genética
[Mh] Termos MeSH secundário: Arabidopsis/genética
Pennisetum/genética
Sementes/genética
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1707
[Cu] Atualização por classe:171010
[Lr] Data última revisão:
171010
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170227
[St] Status:MEDLINE
[do] DOI:10.1007/s00497-017-0298-x



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