Base de dados : MEDLINE
Pesquisa : B01.650.940.800.575.912.250.822.777 [Categoria DeCS]
Referências encontradas : 101 [refinar]
Mostrando: 1 .. 10   no formato [Detalhado]

página 1 de 11 ir para página                         

  1 / 101 MEDLINE  
              next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28152389
[Au] Autor:Mårtensson LM; Carlsson G; Prade T; Kørup K; Lærke PE; Jensen ES
[Ad] Endereço:Swedish University of Agricultural Sciences, Department of Biosystems and Technology, Box 103, SE-230 53 Alnarp, Sweden. Electronic address: Linda.Maria.Martensson@slu.se.
[Ti] Título:Water use efficiency and shoot biomass production under water limitation is negatively correlated to the discrimination against C in the C grasses Dactylis glomerata, Festuca arundinacea and Phalaris arundinacea.
[So] Source:Plant Physiol Biochem;113:1-5, 2017 Apr.
[Is] ISSN:1873-2690
[Cp] País de publicação:France
[La] Idioma:eng
[Ab] Resumo:Climate change impacts rainfall patterns which may lead to drought stress in rain-fed agricultural systems. Crops with higher drought tolerance are required on marginal land with low precipitation or on soils with low water retention used for biomass production. It is essential to obtain plant breeding tools, which can identify genotypes with improved drought tolerance and water use efficiency (WUE). In C plant species, the variation in discrimination against C (Δ C) during photosynthesis has been shown to be a potential indicator for WUE, where discrimination against C and WUE were negatively correlated. The aim of this study was to determine the variation in the discrimination against C between species and cultivars of three perennial C grasses (Dactylis glomerata (cocksfoot), Festuca arundinacea (tall fescue) and Phalaris arundinacea (reed canary grass)) and test the relationships between discrimination against C, season-long water use WUE , shoot and root biomass production in plants grown under well-watered and water-limited conditions. The grasses were grown in the greenhouse and exposed to two irrigation regimes, which corresponded to 25% and 60% water holding capacity, respectively. We found negative relationships between discrimination against C and WUE and between discrimination against C and shoot biomass production, under both the well-watered and water-limited growth conditions (p < 0.001). Discrimination against C decreased in response to water limitation (p < 0.001). We found interspecific differences in the discrimination against C, WUE , and shoot biomass production, where the cocksfoot cultivars showed lowest and the reed canary grass cultivars highest values of discrimination against C. Cocksfoot cultivars also showed highest WUE , shoot biomass production and potential tolerance to water limitation. We conclude that discrimination against C appears to be a useful indicator, when selecting C grass crops for biomass production under drought conditions.
[Mh] Termos MeSH primário: Biomassa
Isótopos de Carbono/metabolismo
Poaceae/fisiologia
Água/metabolismo
[Mh] Termos MeSH secundário: Isótopos de Carbono/análise
Dactylis/crescimento & desenvolvimento
Dactylis/metabolismo
Dactylis/fisiologia
Secas
Festuca/crescimento & desenvolvimento
Festuca/metabolismo
Festuca/fisiologia
Phalaris/crescimento & desenvolvimento
Phalaris/metabolismo
Phalaris/fisiologia
Fotossíntese/fisiologia
Raízes de Plantas/crescimento & desenvolvimento
Brotos de Planta/crescimento & desenvolvimento
Poaceae/crescimento & desenvolvimento
Poaceae/metabolismo
Estações do Ano
Solo/química
Estresse Fisiológico
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Carbon Isotopes); 0 (Soil); 059QF0KO0R (Water)
[Em] Mês de entrada:1707
[Cu] Atualização por classe:171116
[Lr] Data última revisão:
171116
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170203
[St] Status:MEDLINE


  2 / 101 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28091361
[Au] Autor:Al-Mamun M; Shibuya K; Kajita M; Tamura Y; Sano H
[Ad] Endereço:1Deptartment of Animal Science,Iwate University,Morioka 020-8550,Japan.
[Ti] Título:Responses of plasma glucose metabolism to exogenous insulin infusion in sheep-fed forage herb plantain and exposed to heat.
[So] Source:Animal;11(8):1287-1294, 2017 Aug.
[Is] ISSN:1751-732X
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:The use of herbal plants as traditional medicines has a century long history. Plantain (Plantago lanceolata L.) is a perennial herb containing bioactive components with free radical scavenging activities. An isotope dilution technique using [U-13C]glucose was conducted to determine the effect of plantain on the responses of plasma glucose metabolism to exogenous insulin infusion in sheep. Six crossbred sheep (three wethers and three ewes; mean initial BW=40±2 kg) were fed either a mixed hay of orchardgrass (Dactylis glomerata) and reed canarygrass (Phalaris arundinacea) (MH-diet) or mixed hay and fresh plantain (1 : 1 ratio, dry matter basis, PL-diet) and exposed to a thermoneutral (TN, 20°C; 70% relative humidity (RH)) environment or a heat exposure (HE, 30°C; 70% RH) for 5 days using a crossover design for two 23-day periods. The isotope dilution was conducted on days 18 and 23 of the experimental period during TN and HE, respectively. Plasma concentration of α-tocopherol was greater (P<0.0001) for the PL-diet than the MH-diet and remained comparable between environmental treatments. Plasma glucose concentration before isotope dilution technique was reduced for sheep (P=0.05) during HE compared with TN and remained comparable between diets. Plasma glucose turnover rate during the preinfusion period of insulin did not differ (P=0.10) between dietary treatments and between environments (P=0.65). The response of plasma glucose utilization to exogenous insulin administration was lower (P=0.04) for the PL-diet than the MH-diet. Under present experimental conditions, the plantain group was found to be resistant to the effects of insulin infusion.
[Mh] Termos MeSH primário: Glicemia/efeitos dos fármacos
Insulina/administração & dosagem
Plantago
Ovinos/fisiologia
[Mh] Termos MeSH secundário: Animais
Dactylis
Dieta/veterinária
Feminino
Temperatura Alta
Masculino
Phalaris
alfa-Tocoferol/sangue
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Blood Glucose); 0 (Insulin); H4N855PNZ1 (alpha-Tocopherol)
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171030
[Lr] Data última revisão:
171030
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170117
[St] Status:MEDLINE
[do] DOI:10.1017/S1751731116002846


  3 / 101 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:27830352
[Au] Autor:Valverde ME; Orona-Tamayo D; Nieto-Rendón B; Paredes-López O
[Ad] Endereço:Centro de Investigación y de Estudios Avanzados de Instituto Politécnico Nacional, Km. 9.6 Libramiento Norte Carretera Irapuato-León, CP 36821, Irapuato, Guanajuato, Mexico. malevalverde@gmail.com.
[Ti] Título:Antioxidant and Antihypertensive Potential of Protein Fractions from Flour and Milk Substitutes from Canary Seeds (Phalaris canariensis L.).
[So] Source:Plant Foods Hum Nutr;72(1):20-25, 2017 Mar.
[Is] ISSN:1573-9104
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:Canary seed (Phalaris canariensis) is used to feed birds but it has been recently considered a promising cereal with nutraceutical potential for humans. The aim of this work was to analyze the protein fractions from canary seed flour and from milk substitutes (prepared by soaking the seeds in water 12 and 24 h), and to evaluate antioxidant and antihypertensive capacity of peptides obtained after in vitro digestion. Prolamins were the major protein fraction, followed by glutelins. After digestion, albumins and prolamins fractions from milks presented higher levels of peptides than flour, globulins showed more peptides in flour and glutelins were found in similar concentrations in all samples; 24 h milk prolamins had the highest concentration of peptides. Purification by high performance liquid chromatography (HPLC), sequencing of peptides, in vitro antioxidant ABTS (2,2'-azino-bis, 3-ethylbenzothiazoline-6-sulphonic acid) and DPPH (2,2-diphenyl-1-picrylhydrazyl) assays, and antihypertensive capacity (angiotensin converting enzyme (ACE) assay), indicated that peptides from canary seed prolamins were the most efficient compounds with antioxidant and antihypertensive activity. Canary seeds may be considered an accessible and cheap source to prepare milk substitutes with high contents of bioactive peptides with remarkable functional properties to promote better human health and healthy ageing.
[Mh] Termos MeSH primário: Anti-Hipertensivos/análise
Antioxidantes/análise
Suplementos Nutricionais/análise
Farinha/análise
Substitutos do Leite/química
Phalaris/química
[Mh] Termos MeSH secundário: Albuminas/análise
Cromatografia Líquida de Alta Pressão
Globulinas/análise
Glutens/análise
Seres Humanos
Peptídeos/análise
Proteínas de Plantas/análise
Sementes/química
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Albumins); 0 (Antihypertensive Agents); 0 (Antioxidants); 0 (Globulins); 0 (Peptides); 0 (Plant Proteins); 8002-80-0 (Glutens)
[Em] Mês de entrada:1704
[Cu] Atualização por classe:171101
[Lr] Data última revisão:
171101
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161111
[St] Status:MEDLINE
[do] DOI:10.1007/s11130-016-0584-z


  4 / 101 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:27498832
[Au] Autor:Singh R; Ahluwalia V; Singh P; Kumar N; Prakash Sati O; Sati N
[Ad] Endereço:a Department of Chemistry , HNB Garhwal University (A Central University) , Srinagar , India.
[Ti] Título:Antifungal and phytotoxic activity of essential oil from root of Senecio amplexicaulis Kunth. (Asteraceae) growing wild in high altitude-Himalayan region.
[So] Source:Nat Prod Res;30(16):1875-9, 2016 Aug.
[Is] ISSN:1478-6427
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:This work was aimed to evaluate the essential oil from root of medicinally important plant Senecio amplexicaulis for chemical composition, antifungal and phytotoxic activity. The chemical composition analysed by GC/GC-MS showed the presence of monoterpene hydrocarbons in high percentage with marker compounds as α-phellandrene (48.57%), o-cymene (16.80%) and ß-ocimene (7.61%). The essential oil exhibited significant antifungal activity against five phytopathogenic fungi, Sclerotium rolfsii, Macrophomina phaseolina, Rhizoctonia solani, Pythium debaryanum and Fusarium oxysporum. The oil demonstrated remarkable phytotoxic activity in tested concentration and significant reduction in seed germination percentage of Phalaris minor and Triticum aestivum at higher concentrations. The roots essential oil showed high yield for one of its marker compound (α-phellandrene) which makes it important natural source of this compound.
[Mh] Termos MeSH primário: Antifúngicos/farmacologia
Óleos Voláteis/química
Óleos Voláteis/farmacologia
Senécio/química
[Mh] Termos MeSH secundário: Alcenos/análise
Altitude
Antifúngicos/química
Ascomicetos/efeitos dos fármacos
Ascomicetos/patogenicidade
Fusarium/efeitos dos fármacos
Fusarium/patogenicidade
Cromatografia Gasosa-Espectrometria de Massas
Germinação/efeitos dos fármacos
Índia
Monoterpenos/análise
Phalaris/efeitos dos fármacos
Phalaris/crescimento & desenvolvimento
Raízes de Plantas/química
Rhizoctonia/efeitos dos fármacos
Rhizoctonia/patogenicidade
Sementes/efeitos dos fármacos
Sementes/crescimento & desenvolvimento
Triticum/efeitos dos fármacos
Triticum/crescimento & desenvolvimento
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Alkenes); 0 (Antifungal Agents); 0 (Monoterpenes); 0 (Oils, Volatile); 13877-91-3 (beta-ocimene); 49JV13XE39 (alpha phellandrene)
[Em] Mês de entrada:1705
[Cu] Atualização por classe:170817
[Lr] Data última revisão:
170817
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160809
[St] Status:MEDLINE
[do] DOI:10.1080/14786419.2015.1079910


  5 / 101 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Boim, Mirian Aparecida
Texto completo
[PMID]:27232241
[Au] Autor:Passos CS; Ribeiro RS; Rosa TS; Neves RV; Costa F; Ginoza M; Boim MA
[Ad] Endereço:1Renal Division, Department of Medicine, Federal University of São Paulo, São Paulo, BRAZIL; and 2Graduate Program in Physical Education and Health, Catholic University of Brasília, Brasília, BRAZIL.
[Ti] Título:Cardiovascular and Renal Effects of Birdseed Associated with Aerobic Exercise in Rats.
[So] Source:Med Sci Sports Exerc;48(10):1925-34, 2016 Oct.
[Is] ISSN:1530-0315
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:INTRODUCTION: Phalaris canariensis L. (Pc), known as birdseed, is rich in tryptophan. The aqueous extract of Pc (AEPc) treatment reduced systolic blood pressure (SBP) in spontaneously hypertensive rats (SHR) via mechanisms mediated by the tryptophan metabolizing enzyme indoleamine 2,3-dioxygenase (IDO). Hypertension is a risk factor to cardiovascular and renal diseases. Considering that physical exercise improves hypertension and cardiovascular function, the aim of this study was to evaluate whether the benefits of exercise (Ex) would be enhanced by concomitant AEPc treatment (400 mg·kg·d p.o.). METHODS: Vascular reactivity was assessed in aorta rings from SHR treated with AEPc for 4 wk. Training intensity was based on maximal lactate steady state obtained during the 2-wk adaptation period in a treadmill running. Then exercised (60 min running, five times per week during 8 wk) or sedentary SHR were untreated or treated with AEPc during 8 wk. SBP was estimated by plethysmograph. Heart mass and body mass were used to obtain the index of cardiac hypertrophy. Glucose tolerance test was evaluated by oral glucose overload, and the mRNA expressions of indoleamine 2,3-dioxygenase, interleukin 1ß (IL-1ß), and IL-10 in the kidney were obtained by real time polymerase chain reaction. RESULTS: AEPc induced endothelial-mediated vascular relaxation. AEPc or Ex alone reduced SBP, the index of cardiac hypertrophy and ventricular fibrosis, improved glucose metabolism, and attenuated proteinuria and the renal expression of the proinflammatory IL-1ß with an overexpression in the anti-inflammatory IL-10. AEPc potentiated the benefits of the Ex on the cardiovascular system, metabolic parameters, and renal inflammation. CONCLUSION: Birdseed reduced cardiovascular risk related to hypertension and had positive effects when associated to physical exercise.
[Mh] Termos MeSH primário: Pressão Sanguínea/efeitos dos fármacos
Rim/efeitos dos fármacos
Phalaris
Condicionamento Físico Animal/fisiologia
Extratos Vegetais/farmacologia
Triptofano/farmacologia
[Mh] Termos MeSH secundário: Animais
Indolamina-Pirrol 2,3,-Dioxigenase/metabolismo
Interleucina-1beta/metabolismo
Rim/metabolismo
Masculino
Extratos Vegetais/metabolismo
Ratos Endogâmicos SHR
Triptofano/metabolismo
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Indoleamine-Pyrrole 2,3,-Dioxygenase); 0 (Interleukin-1beta); 0 (Plant Extracts); 8DUH1N11BX (Tryptophan)
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170830
[Lr] Data última revisão:
170830
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160528
[St] Status:MEDLINE
[do] DOI:10.1249/MSS.0000000000000995


  6 / 101 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
PubMed Central Texto completo
Texto completo
[PMID]:27005474
[Au] Autor:Barth S; Jankowska MJ; Hodkinson TR; Vellani T; Klaas M
[Ad] Endereço:Teagasc Crops Environment and Land Use Programme, Oak Park Research Centre, Carlow, Ireland. susanne.barth@teagasc.ie.
[Ti] Título:Variation in sequences containing microsatellite motifs in the perennial biomass and forage grass, Phalaris arundinacea (Poaceae).
[So] Source:BMC Res Notes;9:184, 2016 Mar 22.
[Is] ISSN:1756-0500
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Forty three microsatellite markers were developed for further genetic characterisation of a forage and biomass grass crop, for which genomic resources are currently scarce. The microsatellite markers were developed from a normalized EST-SSR library. All of the 43 markers gave a clear banding pattern on 3% Metaphor agarose gels. Eight selected SSR markers were tested in detail for polymorphism across eleven DNA samples of large geographic distribution across Europe. The new set of 43 SSR markers will help future research to characterise the genetic structure and diversity of Phalaris arundinacea, with a potential to further understand its invasive character in North American wetlands, as well as aid in breeding work for desired biomass and forage traits. P. arundinacea is particularly valued in the northern latitude as a crop with high biomass potential, even more so on marginal lands.
[Mh] Termos MeSH primário: Biomassa
Variação Genética
Repetições de Microssatélites/genética
Motivos de Nucleotídeos/genética
Phalaris/genética
[Mh] Termos MeSH secundário: Sequência de Bases
Etiquetas de Sequências Expressas
Genótipo
Polimorfismo de Nucleotídeo Único/genética
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Em] Mês de entrada:1612
[Cu] Atualização por classe:170220
[Lr] Data última revisão:
170220
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160324
[St] Status:MEDLINE
[do] DOI:10.1186/s13104-016-1994-6


  7 / 101 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:26902890
[Au] Autor:Irani M; Razavi SM; Abdel-Aal el-SM; Hucl P; Patterson CA
[Ad] Endereço:Food Hydrocolloids Research Centre, Department of Food Science and Technology, Ferdowsi University of Mashhad (FUM), PO Box 91775-1163, Mashhad, Iran.
[Ti] Título:Dilute solution properties of canary seed (Phalaris canariensis) starch in comparison to wheat starch.
[So] Source:Int J Biol Macromol;87:123-9, 2016 Jun.
[Is] ISSN:1879-0003
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:Dilute solution properties of an unknown starch are important to understand its performance and applications in food and non-food industries. In this paper, rheological and molecular properties (intrinsic viscosity, molecular weight, shape factor, voluminosity, conformation and coil overlap parameters) of the starches from two hairless canary seed varieties (CO5041 & CDC Maria) developed for food use were evaluated in the dilute regime (Starch dispersions in DMSO (0.5g/dl)) and compared with wheat starch (WS). The results showed that Higiro model is the best among five applied models for intrinsic viscosity determination of canary seed starch (CSS) and WS on the basis of coefficient of determination (R(2)) and root mean square error (RMSE). WS sample showed higher intrinsic viscosity value (1.670dl/g) in comparison to CSS samples (1.325-1.397dl/g). Berry number and the slope of master curve demonstrated that CSS and WS samples were in dilute domain without entanglement occurrence. The shape factor suggested spherical and ellipsoidal structure for CO5041 starch and ellipsoidal for CDC Maria starch and WS. The molecular weight, coil radius and coil volume of CSSs were smaller than WS. The behavior and molecular characterization of canary seed starch showed its unique properties compared with wheat starch.
[Mh] Termos MeSH primário: Phalaris/química
Sementes/química
Amido/química
Triticum/química
[Mh] Termos MeSH secundário: Configuração de Carboidratos
Peso Molecular
Reologia
Soluções
Viscosidade
[Pt] Tipo de publicação:COMPARATIVE STUDY; JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Solutions); 9005-25-8 (Starch)
[Em] Mês de entrada:1612
[Cu] Atualização por classe:161230
[Lr] Data última revisão:
161230
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160224
[St] Status:MEDLINE


  8 / 101 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:26841773
[Au] Autor:Antonkiewicz J; Kolodziej B; Bielinska EJ
[Ad] Endereço:Department of Agricultural and Environmental Chemistry, Hugo Kollataj University of Agriculture in Krakow, 21 Mickiewicz St, 31-120, Krakow, Poland. rrantonk@cyf-kr.edu.pl.
[Ti] Título:The use of reed canary grass and giant miscanthus in the phytoremediation of municipal sewage sludge.
[So] Source:Environ Sci Pollut Res Int;23(10):9505-17, 2016 May.
[Is] ISSN:1614-7499
[Cp] País de publicação:Germany
[La] Idioma:eng
[Ab] Resumo:The application of municipal sewage sludge on energy crops is an alternative form of recycling nutrients, food materials, and organic matter from waste. Municipal sewage sludge constitutes a potential source of heavy metals in soil, which can be partially removed by the cultivation of energy crops. The aim of the research was to assess the effect of municipal sewage sludge on the uptake of heavy metals by monocotyledonous energy crops. Sewage sludge was applied at doses of 0, 10, 20, 40, and 60 Mg DM · ha(-1) once, before the sowing of plants. In a 6-year field experiment, the effect of four levels of fertilisation with sewage sludge on the uptake of heavy metals by two species of energy crops, reed canary grass (Phalaris arundinacea L.) of 'Bamse' cultivar and giant miscanthus (Miscanthus × giganteus GREEF et DEU), was analysed. It was established that the increasing doses of sewage sludge had a considerable effect on the increase in biomass yield from the tested plants. Due to the increasing doses of sewage sludge, a significant increase in heavy metals content in the energy crops was recorded. The heavy metal uptake with the miscanthus yield was the highest at a dose of 20 Mg DM · ha(-1), and at a dose of 40 Mg DM · ha(-1) in the case of reed canary grass. Research results indicate that on account of higher yields, higher bioaccumulation, and higher heavy metal uptake, miscanthus can be selected for the remediation of sewage sludge.
[Mh] Termos MeSH primário: Biodegradação Ambiental
Phalaris/metabolismo
Poaceae/metabolismo
Esgotos/química
[Mh] Termos MeSH secundário: Biomassa
Metais Pesados/análise
Phalaris/química
Poaceae/química
Solo/química
Poluentes do Solo/análise
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Metals, Heavy); 0 (Sewage); 0 (Soil); 0 (Soil Pollutants)
[Em] Mês de entrada:1705
[Cu] Atualização por classe:171116
[Lr] Data última revisão:
171116
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160205
[St] Status:MEDLINE
[do] DOI:10.1007/s11356-016-6175-6


  9 / 101 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
[PMID]:26773317
[Au] Autor:Rayburn K
[Ti] Título:Canary Seed in Diabetes: Sweet Harmony?
[So] Source:Altern Ther Health Med;22(1):16-9, 2016 Jan-Feb.
[Is] ISSN:1078-6791
[Cp] País de publicação:United States
[La] Idioma:eng
[Mh] Termos MeSH primário: Diabetes Mellitus/tratamento farmacológico
Phalaris
Sementes
[Mh] Termos MeSH secundário: Hemoglobina A Glicada/análise
Seres Humanos
Hipoglicemiantes
Insulina
Extratos Vegetais/uso terapêutico
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Glycated Hemoglobin A); 0 (Hypoglycemic Agents); 0 (Insulin); 0 (Plant Extracts); 0 (hemoglobin A1c protein, human)
[Em] Mês de entrada:1606
[Cu] Atualização por classe:171116
[Lr] Data última revisão:
171116
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160117
[St] Status:MEDLINE


  10 / 101 MEDLINE  
              first record previous record
seleciona
para imprimir
Fotocópia
[PMID]:26773316
[Au] Autor:Perez Gutierrez RM; Madrigales Ahuatzi D; Cruz Victoria T
[Ti] Título:Inhibition by Seeds of Phalaris canariensis Extracts of Key Enzymes Linked to Obesity.
[So] Source:Altern Ther Health Med;22(1):8-14, 2016 Jan-Feb.
[Is] ISSN:1078-6791
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:CONTEXT: Obesity and its associated diseases are an increasing problem around the world. One hyperglycemic remedy is reduction of glucose absorption performed by suppressing digestion of carbohydrates and lipids through the use of inhibitors. Phalaris canariensis (P canariensis) is a species belonging to the Graminaceae family and is used in traditional medicine in Mexico for treatment of diabetes and obesity. OBJECTIVE: The aim of the study was to evaluate the effects of different extracts of the seeds of P canariensis on enzymes metabolizing fat and carbohydrates, obtained using 3 solvents. DESIGN: The seeds of P canariensis were extracted using hexane (ALH), chloroform (ALC), and methanol (ALM) and were investigated for their antiobesity potential. SETTING: This research was conducted in the Laboratory of Research of Natural Products in the School of Chemical Engineering at the National Polytechnic Institute and in the Research Laboratory of Enzymology in the National School of Biological Sciences. OUTCOME MEASURES: Different concentrations of the extracts were used to study the inhibition of enzymatic activity by porcine pancreatic α-amylase, with carbose as a positive control. The inhibitory activity of α-glucosidase was determined using the standard method with bovine serum albumin (BSA). Pancreatic lipase (PL) activity was measured by absorbance at 412 nm, and the data obtained were compared with orlistat. The PL activity was assessed using a second method measuring the rate of release of oleic acid from triolein. Lipoprotein lipase (LPL) activity was measured by released (3H)-oleic acid. Lipolytic activity in cultured, mouse, 3T3-Ll adipocytes was used as a measure of hormone-sensitive lipase activity. The inhibitory activity of rat intestinal sucrase was determined by measuring the glucose released. A Caco-2 cell assay determined the content of free glucose. RESULTS: The ALH extract of P canariensis showed potent inhibitory activity with IC50 values of 2.13 and 1.25 mg/mL as compared with α-amylase and α-glucosidase, respectively, and produced inhibition in rat intestinal sucrose. Further, the ALM extract showed significantly inhibitory effects against PL, LPL, and lipolysis of 3T3-LI adipocytes. CONCLUSIONS: The results provide evidence for the effects of the seeds of P canariensis for a retarded absorption of carbohydrates and lipids through the inhibition of enzymes that are related to obesity and diabetes mellitus type 2.
[Mh] Termos MeSH primário: Inibidores Enzimáticos/farmacologia
Obesidade/enzimologia
Phalaris/química
Extratos Vegetais/farmacologia
Sementes/química
[Mh] Termos MeSH secundário: Células 3T3
Animais
Células CACO-2
Inibidores Enzimáticos/química
Seres Humanos
Lipase/efeitos dos fármacos
Masculino
Camundongos
Extratos Vegetais/química
Ratos
Solventes
Suínos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Enzyme Inhibitors); 0 (Plant Extracts); 0 (Solvents); EC 3.1.1.3 (Lipase)
[Em] Mês de entrada:1606
[Cu] Atualização por classe:160117
[Lr] Data última revisão:
160117
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160117
[St] Status:MEDLINE



página 1 de 11 ir para página                         
   


Refinar a pesquisa
  Base de dados : MEDLINE Formulário avançado   

    Pesquisar no campo  
1  
2
3
 
           



Search engine: iAH v2.6 powered by WWWISIS

BIREME/OPAS/OMS - Centro Latino-Americano e do Caribe de Informação em Ciências da Saúde