Base de dados : MEDLINE
Pesquisa : B01.650.940.800.575.912.250.859.750.700.500 [Categoria DeCS]
Referências encontradas : 140 [refinar]
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[PMID]:28632185
[Au] Autor:Ambroz M; Matousková P; Skarka A; Zajdlová M; Záková K; Skálová L
[Ad] Endereço:Department of Biochemical Sciences, Faculty of Pharmacy, Charles University, Heyrovského 1203, 50005 Hradec Králové, Czech Republic. ambrozm@faf.cuni.cz.
[Ti] Título:The Effects of Selected Sesquiterpenes from Myrica rubra Essential Oil on the Efficacy of Doxorubicin in Sensitive and Resistant Cancer Cell Lines.
[So] Source:Molecules;22(6), 2017 Jun 20.
[Is] ISSN:1420-3049
[Cp] País de publicação:Switzerland
[La] Idioma:eng
[Ab] Resumo:ß-caryophyllene oxide (CAO), α-humulene (HUM), trans-nerolidol (NER) and valencene (VAL) are constituents of the essential oil of (MEO), which has significant antiproliferative effect in various cancer cell lines. In the present study, we compared the antiproliferative effect of these sesquiterpenes alone and in combination with the cytostatic drug doxorubicin (DOX) in cancer cell lines with different sensitivity to DOX. Two ovarian cancer cell lines (sensitive A2780 and partly resistant SKOV3) and two lymphoblast cancer cell lines (sensitive CCRF/CEM and completely resistant CEM/ADR) were used. The observed effects varied among sesquiterpenes and also differed in individual cell lines, with only VAL being effective in all the cell lines. A strong synergism of DOX with NER was found in the A2780 cells, while DOX acted synergistically with HUM and CAO in the SKOV3 cells. In the CCRF/CEM cells, a synergism of DOX with CAO and NER was observed. In resistant CEM/ADR cells, sesquiterpenes did not increase DOX efficacy, although they significantly increased accumulation of DOX (up to 10-times) and rhodamine-123 (substrate of efflux transporter ABCB1) within cancer cells. In conclusion, the tested sesquiterpenes were able to improve DOX efficacy in the sensitive and partly resistant cancer cells, but not in cells completely resistant to DOX.
[Mh] Termos MeSH primário: Doxorrubicina/farmacologia
Myrica/química
Sesquiterpenos/farmacologia
[Mh] Termos MeSH secundário: Linhagem Celular Tumoral
Proliferação Celular/efeitos dos fármacos
Sobrevivência Celular/efeitos dos fármacos
Doxorrubicina/uso terapêutico
Resistência a Múltiplos Medicamentos/efeitos dos fármacos
Sinergismo Farmacológico
Quimioterapia Combinada
Seres Humanos
Óleos Voláteis/química
Leucemia-Linfoma Linfoblástico de Células Precursoras/tratamento farmacológico
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Oils, Volatile); 0 (Sesquiterpenes); 54W56MD2WD (humulene); 80168379AG (Doxorubicin); 96H21P91IG (valencene); QR6IP857S6 (nerolidol); S2XU9K448U (caryophyllene oxide)
[Em] Mês de entrada:1706
[Cu] Atualização por classe:170630
[Lr] Data última revisão:
170630
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170621
[St] Status:MEDLINE


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[PMID]:27911932
[Au] Autor:Zhang Y; Chen S; Wei C; Gong H; Li L; Ye X
[Ad] Endereço:Zhejiang University, Department of Food Science and Nutrition, Zhejiang Key Laboratory for Agro-Food Processing, Fuli Institute of Food Science, Zhejiang R & D Center for Food Technology and Equipment, Hangzhou, China.
[Ti] Título:Chemical and Cellular Assays Combined with In Vitro Digestion to Determine the Antioxidant Activity of Flavonoids from Chinese Bayberry (Myrica rubra Sieb. et Zucc.) Leaves.
[So] Source:PLoS One;11(12):e0167484, 2016.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Oxidative stress is highly associated with the development of cardiovascular diseases and cancer and has drawn great attention. Natural products suggest a potential role in prevention of these disorders. The aim of this study was to investigate the antioxidant and anti-cancer properties of Chinese bayberry leaves (Myrica rubra Sieb. et Zucc.) flavonoids (BLF) comprehensively through the combination of in vitro digestion, chemical and cellular antioxidant assays. Based on the LC/MS data, the major flavonoids of BLF were myricitrin and quercetin 3-rhamnoside. BLF owned strong chemical and cellular antioxidant activity (CAA) with its CAA value at 4253.884 ± 435.366 µmol of QE/100 g DW. After the in vitro digestion, the total flavonoids content, myricitrin and quercetin 3-rhamnoside decreased significantly (P < 0.05). Lower levels of the total flavonoid content and cellular uptake of myricitrin and quercetin 3-rhamnoside might contribute to the lower CAA value of digested BLF (DBLF). However, DBLF still owns considerable chemical antioxidant activities and CAA compared with many plants. Furthermore, both BLF and DBLF exhibited dose-dependent relationship against HepG2 proliferation. Taken together, BLF has a great potential to be developed as a natural antioxidant for promoting public health.
[Mh] Termos MeSH primário: Antioxidantes
Proliferação Celular/efeitos dos fármacos
Flavonoides
Myrica/química
Folhas de Planta/química
Quercetina
[Mh] Termos MeSH secundário: Antioxidantes/química
Antioxidantes/farmacologia
Flavonoides/química
Flavonoides/farmacologia
Células Hep G2
Seres Humanos
Quercetina/análogos & derivados
Quercetina/química
Quercetina/farmacologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Antioxidants); 0 (Flavonoids); 5Z0ZO61WPJ (myricitrin); 9IKM0I5T1E (Quercetin)
[Em] Mês de entrada:1706
[Cu] Atualização por classe:170630
[Lr] Data última revisão:
170630
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161203
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0167484


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[PMID]:27492128
[Au] Autor:Zhang J; Yamada S; Ogihara E; Kurita M; Banno N; Qu W; Feng F; Akihisa T
[Ad] Endereço:Department of Natural Medicine Chemistry, China Pharmaceutical University, 24 Tongjiaxiang, Nanjing, 210009, P. R. China.
[Ti] Título:Biological Activities of Triterpenoids and Phenolic Compounds from Myrica cerifera Bark.
[So] Source:Chem Biodivers;13(11):1601-1609, 2016 Nov.
[Is] ISSN:1612-1880
[Cp] País de publicação:Switzerland
[La] Idioma:eng
[Ab] Resumo:Seven triterpenoids, 1 - 7, two diarylheptanoids, 8 and 9, four phenolic compounds, 10 - 13, and three other compounds, 14 - 16, were isolated from the hexane and MeOH extracts of the bark of Myrica cerifera L. (Myricaceae). Among these compounds, betulin (1), ursolic acid (3), and myricanol (8) exhibited cytotoxic activities against HL60 (leukemia), A549 (lung), and SK-BR-3 (breast) human cancer cell lines (IC 3.1 - 24.2 µm). Compound 8 induced apoptotic cell death in HL60 cells (IC 5.3 µm) upon evaluation of the apoptosis-inducing activity by flow cytometric analysis and by Hoechst 33342 staining method. Western blot analysis on HL60 cells revealed that 8 activated caspases-3, -8, and -9 suggesting that 8 induced apoptosis via both mitochondrial and death receptor pathways in HL60. Upon evaluation of the melanogenesis-inhibitory activity in B16 melanoma cells induced with α-melanocyte-stimulating hormone (α-MSH), erythrodiol (7), 4-hydroxy-2-methoxyphenyl ß-d-glucopyranoside (13), and butyl quinate (15) exhibited inhibitory effects (65.4 - 86.0% melanin content) with no, or almost no, toxicity to the cells (85.9 - 107.4% cell viability) at 100 µm concentration. In addition, 8, myricanone (9), myricitrin (10), protocatechuic acid (11), and gallic acid (12) revealed potent DPPH radical-scavenging activities (IC 6.9 - 20.5 µm).
[Mh] Termos MeSH primário: Antineoplásicos Fitogênicos/farmacologia
Myrica/química
Fenóis/farmacologia
Casca de Planta/química
Triterpenos/farmacologia
[Mh] Termos MeSH secundário: Antineoplásicos Fitogênicos/química
Antineoplásicos Fitogênicos/isolamento & purificação
Morte Celular/efeitos dos fármacos
Linhagem Celular Tumoral
Sobrevivência Celular/efeitos dos fármacos
Relação Dose-Resposta a Droga
Ensaios de Seleção de Medicamentos Antitumorais
Seres Humanos
Estrutura Molecular
Fenóis/química
Fenóis/isolamento & purificação
Relação Estrutura-Atividade
Triterpenos/química
Triterpenos/isolamento & purificação
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Antineoplastic Agents, Phytogenic); 0 (Phenols); 0 (Triterpenes)
[Em] Mês de entrada:1701
[Cu] Atualização por classe:170117
[Lr] Data última revisão:
170117
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160806
[St] Status:MEDLINE
[do] DOI:10.1002/cbdv.201600247


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[PMID]:27374545
[Au] Autor:Cheng H; Chen J; Chen S; Xia Q; Liu D; Ye X
[Ad] Endereço:College of Biosystems Engineering and Food Science, Zhejiang University, Fuli Institute of Food Science, Zhejiang Key Laboratory for Agro-Food Processing, Zhejiang R & D Center for Food Technology and Equipment, Hangzhou 310058, China.
[Ti] Título:Sensory evaluation, physicochemical properties and aroma-active profiles in a diverse collection of Chinese bayberry (Myrica rubra) cultivars.
[So] Source:Food Chem;212:374-85, 2016 Dec 01.
[Is] ISSN:0308-8146
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:The present study aimed to differentiate the flavor (taste and odor) profiles of 11 Chinese bayberry cultivars (Myrica rubra). The physicochemical analysis for taste indicated the bayberry cultivars were quite different in soluble sugars, organic acids, color, total phenolics and anthocyanin contents. Sucrose was the main soluble sugar in bayberry fruit. Principal component analysis (PCA) of physicochemical properties indicated bayberries could be divided into 5 groups, and the Bi qi cultivar contained the highest brix/acid ratio demonstrating the sweetest taste. PCA of aroma-active profile for odor (analyzed by SPME-GC-MS-O) indicated bayberries could be divided into 3 groups: α-pinene ("pine" odor) for group 1 (four cultivars), ß-caryophyllene and isocaryophyllene ("woody" odor) for group 2 (six cultivars), and ethyl acetate ("overripe" odor) for group 3 (one cultivar). Our research on the physicochemical and active-aroma of 11 bayberry cultivars will help to select suitable cultivars to increase consumer satisfaction.
[Mh] Termos MeSH primário: Aromatizantes/análise
Frutas/química
Myrica/química
Odorantes/análise
Olfato
Paladar
[Mh] Termos MeSH secundário: Cromatografia Gasosa-Espectrometria de Massas
Seres Humanos
Análise de Componente Principal
Percepção Gustatória
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Flavoring Agents)
[Em] Mês de entrada:1701
[Cu] Atualização por classe:170117
[Lr] Data última revisão:
170117
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160705
[St] Status:MEDLINE


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[PMID]:26869450
[Au] Autor:Simpson JP; Thrower N; Ohlrogge JB
[Ad] Endereço:Department of Plant Biology, Michigan State University, East Lansing, MI 48824, USA; Great Lakes Bioenergy Research Center, Michigan State University, East Lansing, MI 48824, USA. Electronic address: simps219@msu.edu.
[Ti] Título:How did nature engineer the highest surface lipid accumulation among plants? Exceptional expression of acyl-lipid-associated genes for the assembly of extracellular triacylglycerol by Bayberry (Myrica pensylvanica) fruits.
[So] Source:Biochim Biophys Acta;1861(9 Pt B):1243-1252, 2016 09.
[Is] ISSN:0006-3002
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:Bayberry (Myrica pensylvanica) fruits are covered with a remarkably thick layer of crystalline wax consisting of triacylglycerol (TAG) and diacylglycerol (DAG) esterified exclusively with saturated fatty acids. As the only plant known to accumulate soluble glycerolipids as a major component of surface waxes, Bayberry represents a novel system to investigate neutral lipid biosynthesis and lipid secretion by vegetative plant cells. The assembly of Bayberry wax is distinct from conventional TAG and other surface waxes, and instead proceeds through a pathway related to cutin synthesis (Simpson and Ohlrogge, 2016). In this study, microscopic examination revealed that the fruit tissue that produces and secretes wax (Bayberry knobs) is fully developed before wax accumulates and that wax is secreted to the surface without cell disruption. Comparison of transcript expression to genetically related tissues (Bayberry leaves, M. rubra fruits), cutin-rich tomato and cherry fruit epidermis, and to oil-rich mesocarp and seeds, revealed exceptionally high expression of 13 transcripts for acyl-lipid metabolism together with down-regulation of fatty acid oxidases and desaturases. The predicted protein sequences of the most highly expressed lipid-related enzyme-encoding transcripts in Bayberry knobs are 100% identical to the sequences from Bayberry leaves, which do not produce surface DAG or TAG. Together, these results indicate that TAG biosynthesis and secretion in Bayberry is achieved by both up and down-regulation of a small subset of genes related to the biosynthesis of cutin and saturated fatty acids, and also implies that modifications in gene expression, rather than evolution of new gene functions, was the major mechanism by which Bayberry evolved its specialized lipid metabolism. This article is part of a Special Issue entitled: Plant Lipid Biology edited by Kent D. Chapman and Ivo Feussner.
[Mh] Termos MeSH primário: Aldeído Oxirredutases/biossíntese
Ácidos Graxos Dessaturases/biossíntese
Metabolismo dos Lipídeos/genética
Triglicerídeos/genética
[Mh] Termos MeSH secundário: Aldeído Oxirredutases/genética
Evolução Molecular
Ácidos Graxos Dessaturases/genética
Frutas/metabolismo
Regulação da Expressão Gênica de Plantas
Myrica/enzimologia
Myrica/genética
Myrica/metabolismo
Folhas de Planta/metabolismo
Sementes/metabolismo
Triglicerídeos/biossíntese
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Triglycerides); EC 1.14.19.- (Fatty Acid Desaturases); EC 1.2.- (Aldehyde Oxidoreductases); EC 1.2.1.- (fatty acid reductase)
[Em] Mês de entrada:1706
[Cu] Atualização por classe:170916
[Lr] Data última revisão:
170916
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160213
[St] Status:MEDLINE


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[PMID]:26744217
[Au] Autor:Simpson JP; Ohlrogge JB
[Ad] Endereço:Department of Plant Biology, Michigan State University, East Lansing, Michigan 48824 Great Lakes Bioenergy Research Center, Michigan State University, East Lansing, Michigan 48824.
[Ti] Título:A Novel Pathway for Triacylglycerol Biosynthesis Is Responsible for the Accumulation of Massive Quantities of Glycerolipids in the Surface Wax of Bayberry (Myrica pensylvanica) Fruit.
[So] Source:Plant Cell;28(1):248-64, 2016 Jan.
[Is] ISSN:1532-298X
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Bayberry (Myrica pensylvanica) fruits synthesize an extremely thick and unusual layer of crystalline surface wax that accumulates to 32% of fruit dry weight, the highest reported surface lipid accumulation in plants. The composition is also striking, consisting of completely saturated triacylglycerol, diacylglycerol, and monoacylglycerol with palmitate and myristate acyl chains. To gain insight into the unique properties of Bayberry wax synthesis, we examined the chemical and morphological development of the wax layer, monitored wax biosynthesis through [(14)C]-radiolabeling, and sequenced the transcriptome. Radiolabeling identified sn-2 monoacylglycerol as an initial glycerolipid intermediate. The kinetics of [(14)C]-DAG and [(14)C]-TAG accumulation and the regiospecificity of their [(14)C]-acyl chains indicated distinct pools of acyl donors and that final TAG assembly occurs outside of cells. The most highly expressed lipid-related genes were associated with production of cutin, whereas transcripts for conventional TAG synthesis were >50-fold less abundant. The biochemical and expression data together indicate that Bayberry surface glycerolipids are synthesized by a pathway for TAG synthesis that is related to cutin biosynthesis. The combination of a unique surface wax and massive accumulation may aid understanding of how plants produce and secrete non-membrane glycerolipids and also how to engineer alternative pathways for lipid production in non-seeds.
[Mh] Termos MeSH primário: Vias Biossintéticas
Frutas/metabolismo
Glicolipídeos/metabolismo
Myrica/metabolismo
Triglicerídeos/biossíntese
Ceras/metabolismo
[Mh] Termos MeSH secundário: Acetatos/metabolismo
Acil Coenzima A/metabolismo
Aciltransferases/metabolismo
Vias Biossintéticas/genética
Radioisótopos de Carbono
Espaço Extracelular/metabolismo
Frutas/crescimento & desenvolvimento
Regulação da Expressão Gênica de Plantas
Genes de Plantas
Modelos Biológicos
Myrica/genética
Myrica/crescimento & desenvolvimento
Óleos Vegetais/metabolismo
Sementes/metabolismo
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Acetates); 0 (Acyl Coenzyme A); 0 (Carbon Radioisotopes); 0 (Glycolipids); 0 (Plant Oils); 0 (Triglycerides); 0 (Waxes); EC 2.3.- (Acyltransferases)
[Em] Mês de entrada:1611
[Cu] Atualização por classe:170220
[Lr] Data última revisão:
170220
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160109
[St] Status:MEDLINE
[do] DOI:10.1105/tpc.15.00900


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[PMID]:26744213
[Au] Autor:Mach J
[Ad] Endereço:Science Editor jmach@aspb.org.
[Ti] Título:Identification of a Distinct, Cutin-Related Pathway for Biosynthesis of Triacylglycerol Lipids in Bayberry.
[So] Source:Plant Cell;28(1):5, 2016 Jan.
[Is] ISSN:1532-298X
[Cp] País de publicação:United States
[La] Idioma:eng
[Mh] Termos MeSH primário: Lipídeos/biossíntese
Myrica
[Mh] Termos MeSH secundário: Triglicerídeos
Ceras/metabolismo
[Pt] Tipo de publicação:COMMENT; EDITORIAL
[Nm] Nome de substância:
0 (Lipids); 0 (Triglycerides); 0 (Waxes)
[Em] Mês de entrada:1608
[Cu] Atualização por classe:170220
[Lr] Data última revisão:
170220
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160109
[St] Status:MEDLINE
[do] DOI:10.1105/tpc.16.00017


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[PMID]:26485638
[Au] Autor:Ambroz M; Hanusová V; Skarka A; Bousová I; Králová V; Langhasová L; Skálová L
[Ad] Endereço:Department of Biochemical Sciences, Charles University in Prague, Faculty of Pharmacy, Hradec Králové, Czech Republic.
[Ti] Título:Essential Oil from Myrica rubra Leaves Potentiated Antiproliferative and Prooxidative Effect of Doxorubicin and its Accumulation in Intestinal Cancer Cells.
[So] Source:Planta Med;82(1-2):89-96, 2016 Jan.
[Is] ISSN:1439-0221
[Cp] País de publicação:Germany
[La] Idioma:eng
[Ab] Resumo:Essential oil from the leaves of Myrica rubra, a subtropical Asian fruit tree traditionally used in folk medicines, has a significant antiproliferative effect in several intestinal cancer cell lines. Doxorubicin belongs to the most important cytostatics used in cancer therapy. The present study was designed to evaluate the effects of defined essential oil from M. rubra leaves on efficacy, prooxidative effect, and accumulation of doxorubicin in cancer cell lines and in non-cancerous cells. For this purpose, intestinal adenocarcinoma CaCo2 cells were used. Human fibroblasts (periodontal ligament) and a primary culture of rat hepatocytes served as models of non-cancerous cells. The results showed that the sole essential oil from M. rubra has a strong prooxidative effect in cancer cells while it acts as a mild antioxidant in hepatocytes. Combined with doxorubicin, the essential oil enhanced the antiproliferative and prooxidative effects of doxorubicin in cancer cells. At higher concentrations, synergism of doxorubicin and essential oil from M. rubra was proved. In non-cancerous cells, the essential oil did not affect the toxicity of doxorubicin and the doxorubicin-mediated reactive oxygen species formation. The essential oil increased the intracellular concentration of doxorubicin and enhanced selectively the doxorubicin accumulation in nuclei of cancer cells. Taken together, essential oil from M. rubra leaves could be able to improve the doxorubicin efficacy in cancer cells due to an increased reactive oxygen species production, and the doxorubicin accumulation in nuclei of cancer cells.
[Mh] Termos MeSH primário: Antineoplásicos Fitogênicos/farmacologia
Doxorrubicina/farmacologia
Myrica/química
Óleos Voláteis/farmacologia
Extratos Vegetais/farmacologia
[Mh] Termos MeSH secundário: Animais
Células CACO-2
Proliferação Celular/efeitos dos fármacos
Células Cultivadas
Sinergismo Farmacológico
Hepatócitos/efeitos dos fármacos
Seres Humanos
Neoplasias Intestinais
Masculino
Ratos
Ratos Wistar
Espécies Reativas de Oxigênio/metabolismo
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Antineoplastic Agents, Phytogenic); 0 (Oils, Volatile); 0 (Plant Extracts); 0 (Reactive Oxygen Species); 80168379AG (Doxorubicin)
[Em] Mês de entrada:1609
[Cu] Atualização por classe:160113
[Lr] Data última revisão:
160113
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:151021
[St] Status:MEDLINE
[do] DOI:10.1055/s-0035-1558083


  9 / 140 MEDLINE  
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[PMID]:26213036
[Au] Autor:Chen YY; Zhang ZH; Zhong CY; Song XM; Lin QH; Huang CM; Huang RH; Chen W
[Ad] Endereço:School of Life Sciences, Fujian Agriculture and Forestry University, Fuzhou 350002, China; South China Botanical Garden, Chinese Academy of Sciences, Guangzhou 510650, China.
[Ti] Título:Functional analysis of differentially expressed proteins in Chinese bayberry (Myrica rubra Sieb. et Zucc.) fruits during ripening.
[So] Source:Food Chem;190:763-770, 2016 Jan 01.
[Is] ISSN:0308-8146
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:This study developed a proteome reference map of Myrica rubra fruits at the green, pink and red stages during ripening using two-dimensional gel electrophoresis (2-DE). Forty-six differentially expressed proteins were detected in the gel, of which 43 were successfully identified by matrix-assisted laser desorption ionization time-of-flight/time-of-flight mass spectrometry and protein database searching. We found that malic enzyme related to the decrease of organic acid acidity was up-regulated. The high abundance of pyruvate decarboxylase and alcohol dehydrogenase may contribute to fruit peculiar fragrant characteristics. Phenylalanine ammonia-lyase, chalcone synthase 11, UDP-glucose:flavonoid 3-O-glucosyltransferase, and anthocyanidin synthase, enzymes involved in the anthocyanin metabolic pathway, were all up-regulated. The physiological data agree with fruit proteome results. These findings provided insights into the metabolic processes and regulatory mechanisms during Chinese bayberry fruit ripening.
[Mh] Termos MeSH primário: Antocianinas/química
Eletroforese em Gel Bidimensional/métodos
Frutas/química
Myrica/química
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Anthocyanins)
[Em] Mês de entrada:1602
[Cu] Atualização por classe:170816
[Lr] Data última revisão:
170816
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:150728
[St] Status:MEDLINE


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[PMID]:26521447
[Au] Autor:Shen SN; Xia FB; Li H; Liu YM; Pan RL
[Ti] Título:[A new cyclic diarylheptanoid from the bark of Myrica rubra].
[So] Source:Yao Xue Xue Bao;50(6):746-8, 2015 Jun.
[Is] ISSN:0513-4870
[Cp] País de publicação:China
[La] Idioma:chi
[Ab] Resumo:To study the chemical constituents from the bark of Myrica rubra, fourteen compounds were isolated from the methanolic extract using various chromatographic techniques, including silica gel, Sephadex LH-20 and preparative HPLC. Their structures were identified on the basis of chemical properties and spectroscopic data, as 3, 5-dimethoxy-4-hydroxymyricanol (1), myricanol (2), myricanone (3), myricanol 11-sulfate (4), myricitrin (5), quercetin (6), quercetin-3-rhamnoside (7), tamarixol (8), uvaol (9), ursolic acid (10), taraxerol (11), myricadiol (12), ß-sitosterol (13) and ß-daucosterol (14). Among them, compound 1 is a new compound, named as 3, 5-dimethoxy-4-hydroxymyricanol, compounds 8, 9 were isolated from the genus Myrica for the first time.
[Mh] Termos MeSH primário: Diarileptanoides/química
Myrica/química
Compostos Fitoquímicos/química
Casca de Planta/química
[Mh] Termos MeSH secundário: Diarileptanoides/isolamento & purificação
Compostos Fitoquímicos/isolamento & purificação
[Pt] Tipo de publicação:ENGLISH ABSTRACT; JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Diarylheptanoids); 0 (Phytochemicals)
[Em] Mês de entrada:1602
[Cu] Atualização por classe:151102
[Lr] Data última revisão:
151102
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:151103
[St] Status:MEDLINE



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