Base de dados : MEDLINE
Pesquisa : B01.650.940.800.575.912.250.859.844 [Categoria DeCS]
Referências encontradas : 44 [refinar]
Mostrando: 1 .. 10   no formato [Detalhado]

página 1 de 5 ir para página              

  1 / 44 MEDLINE  
              next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:27626602
[Au] Autor:Abiodun OO; Oshinloye AO
[Ad] Endereço:Department of Pharmacology and Therapeutics, College of Medicine, University of Ibadan, Ibadan, Nigeria.
[Ti] Título:Carpolobia lutea G. Don (Polygalaceae) Inhibits Inflammation and Oxidative Stress in an Acetic Acid Induced Model of Rat Colitis.
[So] Source:Drug Res (Stuttg);67(1):20-24, 2017 Jan.
[Is] ISSN:2194-9387
[Cp] País de publicação:Germany
[La] Idioma:eng
[Ab] Resumo:G. Don (CL) is used in folk medicine for the treatment of inflammatory disorders. Effort in this study is to evaluate the beneficial effect of the aqueous-methanol extract of leaf of CL in a rat model of acetic acid induced colitis. Male Wistar rats were distributed into 6 groups of 7 rats each; non colitic, untreated colitic and colitic rats treated with graded doses of CL (100-800 mg/kg). Rats were pre-treated for 2 days before colitis induction and thereafter for 7 days post colitic induction. 24 h after the last treatment, animals were sacrificed and colonic inflammation was evaluated both macroscopically and biochemically. Macroscopic damage score, weight/length ratio, myeloperoxidase (MPO) activity and tumor necrotic factor alpha (TNF-α) levels, were significantly higher in untreated colitic rats in comparison with non colitic rats (P<0.05). Treatment with CL significantly reduced the macroscopic damage scores, neutrophil infiltration (MPO activity) and TNF-α level (P<0.05). In addition, significantly prevented depletion of colonic GSH and (SOD) levels (P<0.05). It appears that the beneficial effect of methanol extract of leaf observed in this study is dose dependent and is related to its antioxidant and anti-inflammatory activity.
[Mh] Termos MeSH primário: Colite Ulcerativa/tratamento farmacológico
Inflamação/tratamento farmacológico
Estresse Oxidativo/efeitos dos fármacos
Fitoterapia
Extratos Vegetais/farmacologia
Extratos Vegetais/uso terapêutico
Polygalaceae/química
[Mh] Termos MeSH secundário: Ácido Acético
Animais
Anti-Inflamatórios/farmacologia
Colite Ulcerativa/induzido quimicamente
Colite Ulcerativa/complicações
Colo/metabolismo
Colo/patologia
Modelos Animais de Doenças
Relação Dose-Resposta a Droga
Glutationa/metabolismo
Inflamação/complicações
Inflamação/patologia
Masculino
Peroxidase/metabolismo
Extratos Vegetais/química
Folhas de Planta/química
Ratos
Superóxido Dismutase/metabolismo
Fator de Necrose Tumoral alfa/metabolismo
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Anti-Inflammatory Agents); 0 (Plant Extracts); 0 (Tumor Necrosis Factor-alpha); EC 1.11.1.7 (Peroxidase); EC 1.15.1.1 (Superoxide Dismutase); GAN16C9B8O (Glutathione); Q40Q9N063P (Acetic Acid)
[Em] Mês de entrada:1704
[Cu] Atualização por classe:170418
[Lr] Data última revisão:
170418
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160915
[St] Status:MEDLINE
[do] DOI:10.1055/s-0042-114572


  2 / 44 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:27681647
[Au] Autor:Kenmogne H; Koloko B; Hambe C; Domkam J; Ngaha Njila M; Bend E; Oundoum Oundoum P; Massoma Lembè D; Dimo T
[Ad] Endereço:Department of Animal Sciences, Faculty of Science, University of Douala, Douala, Cameroon.
[Ti] Título:Effects of aqueous root extract of Carpolobia alba G. Don on sexual behaviour in adult male rats.
[So] Source:Andrologia;48(8):908-14, 2016 Oct.
[Is] ISSN:1439-0272
[Cp] País de publicação:Germany
[La] Idioma:eng
[Ab] Resumo:Several lines say that a number of natural products, mostly plant based, have been claimed to cure male sexual dysfunction. One of such botanicals is Carpolobia alba G. Don which is used in Cameroon to treat erectile dysfunction and related male sexual debilities. However, the traditional claim has not been scientifically tested. Thirty adult male rats (five groups of six animals) were orally treated daily with distilled water, sildenafil citrate (positive control), 75, 150, 300 mg/kg of C. alba G. Don roots aqueous extract. The erection and ejaculation properties were recorded on the first, seventh and fourteenth day of treatment by following copulation settings: number of erections (NE), mount frequency (MF), intromission frequency (IF), ejaculation frequency (EF), mount latency (ML), intromission latency (IL), ejaculation latency (EL), average interval of copulation (AIC) and post-ejaculatory interval (PEI). The extract resulted in an improvement of copulation parameters through significant reduction (p < .001) of PEI, ML and IL and significant increase (p < .001) in the NE, MF, IF, EF, EL and AIC. These results indicate a pro-erectile and pro-ejaculatory potential of aqueous root extract of this plant in male rats.
[Mh] Termos MeSH primário: Ejaculação/efeitos dos fármacos
Ereção Peniana/efeitos dos fármacos
Extratos Vegetais/farmacologia
Raízes de Plantas
Polygalaceae
Comportamento Sexual Animal/efeitos dos fármacos
[Mh] Termos MeSH secundário: Animais
Copulação/efeitos dos fármacos
Masculino
Ratos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Plant Extracts)
[Em] Mês de entrada:1701
[Cu] Atualização por classe:170124
[Lr] Data última revisão:
170124
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160930
[St] Status:MEDLINE
[do] DOI:10.1111/and.12678


  3 / 44 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:25878092
[Au] Autor:Mennes CB; Moerland MS; Rath M; Smets EF; Merckx VS
[Ad] Endereço:Naturalis Biodiversity Center, Leiden University, P.O. Box 9517, Leiden, the Netherlands.
[Ti] Título:Evolution of mycoheterotrophy in Polygalaceae: The case of Epirixanthes.
[So] Source:Am J Bot;102(4):598-608, 2015 Apr.
[Is] ISSN:1537-2197
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:PREMISE OF THE STUDY: The mycoheterotrophic lifestyle has enabled some plant lineages to obtain carbon from their mycorrhizal symbionts. The mycoheterotrophic genus Epirixanthes (Polygalaceae) consists of six species from tropical Asia. Although it is probably closely related to the chlorophyllous genus Salomonia and linked to arbuscular mycorrhizal fungi, lack of DNA sequence data has thus far prevented these hypotheses from being tested. Therefore, the evolutionary history of Epirixanthes remains largely unknown. METHODS: We reconstructed the phylogenetic relationships of Epirixanthes based on nuclear ITS and plastid matK data. Divergence times were inferred using a Bayesian relaxed clock approach, and we phylogenetically analyzed its mycorrhizal symbionts. We furthermore assigned these symbionts to operational taxonomic units, compared them with symbionts of other Polygalaceae, and measured their phylogenetic diversity. KEY RESULTS: We found that Epirixanthes is placed in tribe Polygaleae as sister to Salomonia. Epirixanthes has a Miocene-Oligocene stem age and grows exclusively in symbiosis with fungi of Glomeraceae. Salomonia and some Polygala species are linked to both Glomeraceae and Acaulosporaceae, resulting in higher phylogenetic diversity values. The majority of the symbionts of Epirixanthes are not found in Salomonia or Polygala, although a few shared fungal taxa are found. CONCLUSIONS: Epirixanthes forms a relatively young mycoheterotrophic lineage. The Oligocene-Miocene origin suggests its evolution was influenced by the environmental dynamics in Southeast Asia during this time. Although comparison of fungi from Epirixanthes with those from Salomonia and Polygala suggests some specialization, many other mycoheterotrophic plants are linked to a more narrow set of Glomeraceae.
[Mh] Termos MeSH primário: Evolução Biológica
Glomeromycota/fisiologia
Micorrizas/fisiologia
Polygalaceae/microbiologia
Polygalaceae/fisiologia
[Mh] Termos MeSH secundário: Bornéu
DNA Fúngico/genética
DNA Intergênico/genética
DNA de Plantas/genética
Evolução Molecular
Glomeromycota/classificação
Glomeromycota/genética
Malásia
Dados de Sequência Molecular
Micorrizas/classificação
Micorrizas/genética
Filogenia
Proteínas de Plantas/genética
Polygalaceae/classificação
Polygalaceae/genética
RNA Ribossômico 18S/genética
Análise de Sequência de DNA
Simbiose
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (DNA, Fungal); 0 (DNA, Intergenic); 0 (DNA, Plant); 0 (Plant Proteins); 0 (RNA, Ribosomal, 18S)
[Em] Mês de entrada:1605
[Cu] Atualização por classe:150416
[Lr] Data última revisão:
150416
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:150417
[St] Status:MEDLINE
[do] DOI:10.3732/ajb.1400549


  4 / 44 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:25546625
[Au] Autor:Filho Hda S; Pacheco LC; Andrade Eda S; Correa MJ; Araújo RN; Guilhon GM; Silva JK; Santos LS
[Ad] Endereço:Instituto de Ciências Exatas e Naturais, Universidade Federal do Pará-UFPA, Rua Augusto Corrêa, S/N, 66075-900 Belém-PA, Brazil. ripardofilho@ufpa.br.
[Ti] Título:Xanthones from the roots of Moutabea guianensis Aubl.
[So] Source:Molecules;20(1):127-34, 2014 Dec 23.
[Is] ISSN:1420-3049
[Cp] País de publicação:Switzerland
[La] Idioma:eng
[Ab] Resumo:The phytochemical investigation of Moutabea guianensis roots led to the isolation of five polyoxygenated xanthones, including two new ones named moutabeone B (1,8-dihydroxy-4,5,6,7-tetramethoxyxanthone) and moutabeone C (1-hydroxy-4,5,6,7,8-pentamethoxyxanthone), along with the three known xanthones, 1,8-dihydroxy-4,6-dimethoxyxanthone, 1,8-dihydroxy-4,5,6-trimethoxyxanthone and augustin A (1,8-dihydroxy-4,6,7-trimethoxyxanthone). Structural characterization of all compounds was established on the basis of spectroscopic methods, mainly 1D and 2D nuclear magnetic resonance (NMR) and comparison with literature data. The antioxidant activity of compounds was tested through a thin layer chromatography (TLC) bioautography assay using 1,1-diphenyl-2-picryl-hydrazyl radical (DPPH·) as detection reagent. All tested compounds were more active (DL < 0.13-0.03 µg) than Trolox (DL < 0.15 µg), used as reference standard.
[Mh] Termos MeSH primário: Raízes de Plantas/química
Polygalaceae/química
Xantonas/isolamento & purificação
[Mh] Termos MeSH secundário: Cromatografia em Camada Delgada
Espectroscopia de Ressonância Magnética
Xantonas/química
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Xanthones)
[Em] Mês de entrada:1510
[Cu] Atualização por classe:141230
[Lr] Data última revisão:
141230
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:141230
[St] Status:MEDLINE
[do] DOI:10.3390/molecules20010127


  5 / 44 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Vilegas, Wagner
PubMed Central Texto completo
[PMID]:25435605
[Au] Autor:Nwidu LL; Ukiri OO; Rodrigues CM; Vilegas W
[Ad] Endereço:Department of Pharmacology and Toxicology, Faculty of Pharmacy, Niger Delta University, Wilberforce Island Bayelsa State, Nigeria; P.O. Box 10935, Port Harcourt Nigeria.
[Ti] Título:Antidiarrheal mechanism and ionic profile of Carpolobia lutea ethanolic stem-bark extract in rats.
[So] Source:Afr J Tradit Complement Altern Med;11(2):257-63, 2014.
[Is] ISSN:2505-0044
[Cp] País de publicação:Nigeria
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: The stem-bark extract of Carpolobia lutea (Polygalaceae), used in ethno-medicine as anti-diarrhea was pharmacologically evaluated. This was the first report of assessment of the ethanolic stem extract (ESE), of C. lutea as anti-diarrhoeal agent in rats. The anti-diarrhoeal effects, acute toxicity and ionic profile are investigated and reported. MATERIALS AND METHODS: The acute toxicity was established using Lock's method. The anti-diarrhoeal effects were demonstrated using castor oil-induced diarrheal and fluid accumulation and its effect on normal intestinal transit. The mechanism elucidated using yohimbine, isosorbide dinitrate, and diphenoxylate. The elemental and ionic profile of ESE was established using inductively coupled argon-plasma emission spectrometer and potentiometric titration respectively. The finger print of ESE was revealed by Jasco (Tokyo, Japan), HPLC and active compounds by phytochemical screening using standard procedure. RESULTS: The LD50 obtained is 866.025 mg/kg (i.p). The doses of 43.3, 86.6, and 173.2 mg/kg of ESE showed inhibition of castor oil-induced diarrheal (p<0.05 -0.001). The most abundant cations in the extract are potassium and phosphorus (1.00 ±0.01 and 0.80 ± 0.030 mg/g respectively); while the most abundant anions are phosphate and sulphate (33.50±7.09 and 7.19±3.29 mg/g respectively). The HPLC fingerprint of ESE revealed UV spectra of biomolecules. Phytochemical screening revealed presence of saponins, polyphenols and glycosides. CONCLUSION: These investigations indicate presence of bioactive and elemental substances which could play major role in diarrheal management. This investigation justifies the use of stem-bark of C. lutea in illicit gin (akpatashi), among the Effiks in Nigeria as antidiarrheal.
[Mh] Termos MeSH primário: Antidiarreicos/administração & dosagem
Diarreia/tratamento farmacológico
Casca de Planta/química
Extratos Vegetais/administração & dosagem
Polygalaceae/química
[Mh] Termos MeSH secundário: Animais
Antidiarreicos/análise
Feminino
Seres Humanos
Masculino
Camundongos
Nigéria
Extratos Vegetais/análise
Caules de Planta/química
Ratos
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Antidiarrheals); 0 (Plant Extracts)
[Em] Mês de entrada:1507
[Cu] Atualização por classe:170220
[Lr] Data última revisão:
170220
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:141202
[St] Status:MEDLINE


  6 / 44 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
[PMID]:25026713
[Au] Autor:Dibwe DF; Awale S; Kadota S; Morita H; Tezuka Y
[Ti] Título:Two new diphenylmethyl-substituted xanthones from Seicuridaca longepedunculata.
[So] Source:Nat Prod Commun;9(5):655-7, 2014 May.
[Is] ISSN:1934-578X
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Two new diphenylmethyl-substituted xanthones, named muchimangins K (1) and L (2), have been isolated from the roots of Securidaca longepedunculata (Polygalaceae) collected in the Democratic Republic of Congo. Their structures were established by analyses of the spectral data, including 2D NMR spectra, to be 1 ,3,6,8-tetrahydroxy-2.5-dimethoxy-4-[ -(2,4,5-trimethoxyphenyl)-1-phenylmethyl]xanthone (1) and 1,3,6-trihydroxy-4,7-dimethoxy-2-[1-(2,4,5-trimethoxyphenyl)- 1-phenylmethyl]xanthone (2).
[Mh] Termos MeSH primário: Polygalaceae/química
Xantonas/isolamento & purificação
[Mh] Termos MeSH secundário: Espectroscopia de Ressonância Magnética
Raízes de Plantas/química
Xantonas/química
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Xanthones); 0 (muchimangin K); 0 (muchimangin L)
[Em] Mês de entrada:1409
[Cu] Atualização por classe:140716
[Lr] Data última revisão:
140716
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:140717
[St] Status:MEDLINE


  7 / 44 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:24972272
[Au] Autor:da S Ripardo Filho H; Pacheco LC; da S Andrade E; Correa MJ; Guilhon GM; Santos LS
[Ad] Endereço:Instituto de Ciências Exatas e Naturais, Universidade Federal do Pará-UFPA, Rua Augusto Corrêa, S/N, 66075-900 Belém-PA, Brazil. ripardofilho@ufpa.br.
[Ti] Título:A new xanthone from Moutabea guianensis Aubl.
[So] Source:Molecules;19(7):8885-9, 2014 Jun 26.
[Is] ISSN:1420-3049
[Cp] País de publicação:Switzerland
[La] Idioma:eng
[Ab] Resumo:The ethyl acetate extract of the roots of Moutabea guianensis gave 1,6-dihydroxy-4,7,8-trimethoxy-9H-xanthen-9-one (1), a new xanthone. The isolation was accomplished by column chromatography on silica gel and the structural elucidation of this compound was established by spectroscopic analyses including 1D and 2D NMR and HRESIMS.
[Mh] Termos MeSH primário: Extratos Vegetais/isolamento & purificação
Raízes de Plantas/química
Polygalaceae/química
Xantonas/isolamento & purificação
[Mh] Termos MeSH secundário: Extratos Vegetais/química
Xantonas/química
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Plant Extracts); 0 (Xanthones)
[Em] Mês de entrada:1502
[Cu] Atualização por classe:140628
[Lr] Data última revisão:
140628
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:140628
[St] Status:MEDLINE
[do] DOI:10.3390/molecules19078885


  8 / 44 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:24073857
[Au] Autor:Manfo FP; Nantia EA; Dechaud H; Tchana AN; Zabot MT; Pugeat M; Moundipa PF
[Ad] Endereço:Department of Biochemistry and Molecular Biology, Faculty of Science, University of Buea , Buea , Cameroon .
[Ti] Título:Protective effect of Basella alba and Carpolobia alba extracts against maneb-induced male infertility.
[So] Source:Pharm Biol;52(1):97-104, 2014 Jan.
[Is] ISSN:1744-5116
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:CONTEXT: Male infertility is one of the leading causes of social frustration and marginalization, mainly in the developing world. It is attributed to many factors including exposure to agropesticides such as manganese ethylenebis (dithiocarbamate) (maneb), which is one of the most frequently used fungicides in Cameroon. Previous reports support efficiency of some medicinal plants commonly used in Cameroonian folk medicine for the treatment of this disorder. OBJECTIVE: The present study was aimed at assessing the protective effect of extracts from selected plant species, namely Basella alba L. (Basellaceae) (MEBa) and Carpolobia alba G. Don (Polygalaceae) (AECa), in alleviating the maneb-induced impairment of male reproductive function in Wistar albino rats. MATERIALS AND METHODS: The rats were treated with vehicle, plant extract (MEBa or AECa), maneb and maneb plus plant extract, respectively, and their fertility was assessed. Animals were thereafter sacrificed and organs (liver, kidneys and reproductive organs) were dissected out and weighed. Serum androgens together with alanine aminotransferase, liver glutathione and thiobarbituric acid reactive species (TBARS) were also measured. RESULTS AND DISCUSSION: From this study, both plant extracts stimulated testosterone and improved fertility. Administration of MEBa plus maneb prevented fertility reduction by maneb and minimized the inhibitory effect of maneb on testosterone levels. AECa also improved fertility of the maneb-exposed rats, though without restoring testosterone levels, and other investigated parameters remained unaffected by different treatments. CONCLUSION: These findings emphasized the beneficial effects of B. alba and C. alba extracts on male fertility, and suggest their protective effect against maneb-induced toxicity in male reproductive function.
[Mh] Termos MeSH primário: Infertilidade Masculina/prevenção & controle
Magnoliopsida/química
Extratos Vegetais/farmacologia
Polygalaceae/química
[Mh] Termos MeSH secundário: Animais
Camarões
Modelos Animais de Doenças
Fungicidas Industriais/toxicidade
Masculino
Maneb/toxicidade
Medicina Tradicional
Ratos
Ratos Wistar
Testosterona/sangue
[Pt] Tipo de publicação:COMPARATIVE STUDY; JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Fungicides, Industrial); 0 (Plant Extracts); 12427-38-2 (Maneb); 3XMK78S47O (Testosterone)
[Em] Mês de entrada:1409
[Cu] Atualização por classe:171116
[Lr] Data última revisão:
171116
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:131001
[St] Status:MEDLINE
[do] DOI:10.3109/13880209.2013.816860


  9 / 44 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
[PMID]:24937388
[Au] Autor:Ajiwhen IO; Bisong SA
[Ad] Endereço:Department of Human Physiology, University of Calabar, Calabar. tuk2robo@yahoo.com.
[Ti] Título:Effect of ethanolic extract of Carpolobia lutea G. Don (polygalaceae) root on learning and memory in CD1 mice.
[So] Source:Niger J Physiol Sci;28(2):141-5, 2013 Dec 20.
[Is] ISSN:0794-859X
[Cp] País de publicação:Nigeria
[La] Idioma:eng
[Ab] Resumo:Carpolobia lutea, commonly called cattle stick or poor man's candle, is used by traditional herbalists in eastern Nigeria to treat 'madness'. It has a reported analgesic and anti-nociceptive effect. The effect of its ethanolic root extract on learning and memory was investigated. Thirty mice were divided into three groups of ten each. One group of mice served as the control and was given normal saline (p.o.) while the other two groups were given acute low dose (1500mg/kg, p.o.) and high dose (2500mg/kg, p.o.) (LD50 3338.83mg/kg). The effect of the extract on cognitive memory was investigated using the Novel Object recognition task (NORT) while the effect on visuospatial learning and memory was studied using the Morris Water maze (MWM). The results obtained in the NORT show that the index of habituation was significantly lower following acute treatment with a low dose of C. lutea extract compared to control. However, the index of habituation did not differ following treatment with a high dose of C. lutea compared to control but it was higher compared to the low dose. Following treatment with a low dose of the extract, the index of discrimination was significantly higher compared to control. The index of discrimination in the high dose treatment group did not differ from control, but it was lower compared to the low dose treatment. This indicated that there was improved cognitive memory only in the low dose treatment group. In the MWM there was no significant difference in swim latency during Acquisition and Reversal training. There also was no significant difference in quadrant duration during probe trial. The swim latency during the visible platform test showed that all mice used had good visual acuity. Therefore, the ethanolic extract of C. lutea root enhanced cognitive memory. However it did not affect visuospatial learning and memory.
[Mh] Termos MeSH primário: Comportamento Animal/efeitos dos fármacos
Etanol/química
Aprendizagem/efeitos dos fármacos
Memória/efeitos dos fármacos
Extratos Vegetais/farmacologia
Polygalaceae
Solventes/química
[Mh] Termos MeSH secundário: Animais
Cognição/efeitos dos fármacos
Discriminação (Psicologia)/efeitos dos fármacos
Relação Dose-Resposta a Droga
Habituação Psicofisiológica/efeitos dos fármacos
Camundongos
Atividade Motora/efeitos dos fármacos
Fitoterapia
Extratos Vegetais/química
Extratos Vegetais/isolamento & purificação
Raízes de Plantas
Plantas Medicinais
Polygalaceae/química
Tempo de Reação/efeitos dos fármacos
Recognição (Psicologia)/efeitos dos fármacos
Fatores de Tempo
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Plant Extracts); 0 (Solvents); 3K9958V90M (Ethanol)
[Em] Mês de entrada:1502
[Cu] Atualização por classe:140618
[Lr] Data última revisão:
140618
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:140618
[St] Status:MEDLINE


  10 / 44 MEDLINE  
              first record previous record
seleciona
para imprimir
Fotocópia
Vilegas, Wagner
PubMed Central Texto completo
[PMID]:23983362
[Au] Autor:Nwidu LL; Nwafor PA; Vilegas W
[Ad] Endereço:Department of Pharmacology and Toxicology, Faculty of Pharmacy, Niger Delta University, Wilberforce Island, Bayelsa State, Nigeria. menelucky@yahoo.com
[Ti] Título:Antimicrobial activity of Carpolobia lutea extracts and fractions.
[So] Source:Afr J Tradit Complement Altern Med;9(3):323-8, 2012.
[Is] ISSN:2505-0044
[Cp] País de publicação:Nigeria
[La] Idioma:eng
[Ab] Resumo:Carpolobia lutea (G. Don) (Polygalaceae) is a tropical medicinal plant putative in traditional medicines against gonorrhea, gingivitis, infertility, antiulcer and malaria. The present study evaluated the antimicrobial, antifungal and antihelicobacter effects of extracts C. lutea leaf, stem and root. The extracts were examined using the disc-diffusion and Microplates of 96 wells containing Muller-Hinton methods against some bacterial strains: Eschericia coli (ATCC 25922), E. coli (ATCC10418), Pseudomonas aeruginosa (ATCC 27853), Staphylococcus aureus (ATCC 25923), Staphyllococus aureus (ATCC 6571), Enterococcus faecalis (ATCC 29212) and Bacillus subtilis (NCTC 8853) and four clinical isolates: one fungi (Candida albican) and three bacteria (Salmonella, Sheigella and staphylococcus aureus). The Gram-positive bacteria: Staphylococcus aureus (ATCC 25923), Enterococcus faecalis (ATCC 29212), Bacillus subtilis (ATCC 19659) and the Gram-negative bacteria: Escherichia coli (ATCC 25922), Pseudomonas aeruginosa (ATCC 27853), Cândida albicans (ATCC 18804) and Helicobacter pylori (ATCC 43504). Some of these extracts were found to be active against some tested strains but activity against H. pylori was >1000mg/ml and good fungistatic activity against C. albican. The MIC against C. albican is in the order n-HF > CHF > ETF= EAF.The order of potency of fraction was the ethanol root > n-HF leaf > ethanol fraction stem > chloroform fraction leaf = ethyl acetate fraction leaf. Polyphenols were demonstrated in ethanol fraction, ethyl acetate fraction, crude ethyl acetate extract and ethanol extract, respectively. These polyphenols isolated may partly explain and support the use of C. lutea for the treatment of infectious diseases in traditional Ibibio medicine of Nigeria.
[Mh] Termos MeSH primário: Antibacterianos/farmacologia
Antifúngicos/farmacologia
Bactérias/efeitos dos fármacos
Candida albicans/efeitos dos fármacos
Extratos Vegetais/farmacologia
Polygalaceae
[Mh] Termos MeSH secundário: Nigéria
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Anti-Bacterial Agents); 0 (Antifungal Agents); 0 (Plant Extracts)
[Em] Mês de entrada:1403
[Cu] Atualização por classe:170217
[Lr] Data última revisão:
170217
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:130829
[St] Status:MEDLINE



página 1 de 5 ir para página              
   


Refinar a pesquisa
  Base de dados : MEDLINE Formulário avançado   

    Pesquisar no campo  
1  
2
3
 
           



Search engine: iAH v2.6 powered by WWWISIS

BIREME/OPAS/OMS - Centro Latino-Americano e do Caribe de Informação em Ciências da Saúde