Base de dados : MEDLINE
Pesquisa : B01.650.940.800.575.912.250.938 [Categoria DeCS]
Referências encontradas : 28 [refinar]
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  1 / 28 MEDLINE  
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[PMID]:27706569
[Au] Autor:Shen WH; Li ZH; Peng YH; Yang MH; Tan ZQ; Zheng W
[Ad] Endereço:Central South University of Forestry and Technology, Changsha, Hunan, China.
[Ti] Título:Development and characterization of microsatellite loci in Excentrodendron hsienmu (Chun & How) H.T. Chang& R.H. Miau.
[So] Source:Genet Mol Res;15(3), 2016 Aug 19.
[Is] ISSN:1676-5680
[Cp] País de publicação:Brazil
[La] Idioma:eng
[Ab] Resumo:Microsatellite markers were isolated using dual-suppression-PCR for the endangered species Excentrodendron hsienmu (Tiliaceae) to evaluate the genetic diversity and population structure of this species. A total of 11 polymorphic microsatellite loci were characterized in E. hsienmu. The number of alleles per locus ranged from 2 to 9, with an average of 5.27. The expected heterozygosity value ranged from 0.053 to 0.780, with an average of 0.568 and the observed heterozygosity value ranged from 0 to 0.595, with an average of 0.268. The polymorphic information content value ranged from 0.051 to 0.740, with an average of 0.521. These newly designed markers will be of great potential significance and profound influence in future research related to the genetic diversity, population structure, and patterns of gene flow of this species, which will contribute to the implementation of conservation and management strategies for this species.
[Mh] Termos MeSH primário: Repetições de Microssatélites
Tiliaceae/genética
[Mh] Termos MeSH secundário: Alelos
DNA de Plantas/genética
Espécies em Perigo de Extinção
Loci Gênicos
Variação Genética
Heterozigoto
Polimorfismo Genético
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (DNA, Plant)
[Em] Mês de entrada:1704
[Cu] Atualização por classe:170403
[Lr] Data última revisão:
170403
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161006
[St] Status:MEDLINE
[do] DOI:10.4238/gmr.15038060


  2 / 28 MEDLINE  
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[PMID]:26006030
[Au] Autor:Aziz MA
[Ad] Endereço:Department of Pharmacy, Stamford University Bangladesh, Dhaka-1217, Bangladesh.
[Ti] Título:Qualitative phytochemical screening and evaluation of anti-inflammatory, analgesic and antipyretic activities of Microcos paniculata barks and fruits.
[So] Source:J Integr Med;13(3):173-84, 2015 May.
[Is] ISSN:2095-4964
[Cp] País de publicação:China
[La] Idioma:eng
[Ab] Resumo:OBJECTIVE: The main objectives of this study were to qualitatively evaluate the profile of phytochemical constituents present in methanolic extract of Microcos paniculata bark (BME) and fruit (FME), as well as to evaluate their anti-inflammatory, analgesic and antipyretic activities. METHODS: Phytochemical constituents of BME and FME were determined by different qualitative tests such as Molisch's test, Fehling's test, alkaloid test, frothing test, FeCl3 test, alkali test, Salkowski's test and Baljet test. The anti-inflammatory, analgesic and antipyretic activities of the extracts were evaluated through proteinase-inhibitory assay, xylene-induced ear edema test, cotton pellet-induced granuloma formation in mice, formalin test, acetic acid-induced writhing test, tail immersion test and Brewer's yeast-induced pyrexia in mice. RESULTS: M. paniculata extracts revealed the presence of carbohydrates, alkaloids, saponins, tannins, flavonoids and triterpenoids. All of the extracts showed significant (P<0.05, vs aspirin group) proteinase-inhibitory activity, whereas the highest effect elicited by plant extracts was exhibited by the BME (75.94% proteinase inhibition activity) with a half-maximal inhibitory concentration (IC50) of 61.31 µg/mL. Each extract at the doses of 200 and 400 mg/kg body weight showed significant (P<0.05, vs control) percentage inhibition of ear edema and granuloma formation. These extracts significantly (P<0.05, vs control) reduced the paw licking and abdominal writhing of mice. In addition, BME 400 mg/kg, and FME at 200 and 400 mg/kg showed significant (P<0.05, vs control) analgesic activities at 60 min in the tail immersion test. Again, the significant (P<0.05, vs control) post-treatment antipyretic activities were found by BME 200 and 400 mg/kg and FME 400 mg/kg respectively. CONCLUSION: Study results indicate that M. paniculata may provide a source of plant compounds with anti-inflammatory, analgesic and antipyretic activities.
[Mh] Termos MeSH primário: Analgésicos/farmacologia
Anti-Inflamatórios/farmacologia
Antipiréticos/farmacologia
Extratos Vegetais/farmacologia
Tiliaceae/química
[Mh] Termos MeSH secundário: Animais
Feminino
Frutas/química
Masculino
Camundongos
Casca de Planta/química
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Analgesics); 0 (Anti-Inflammatory Agents); 0 (Antipyretics); 0 (Plant Extracts)
[Em] Mês de entrada:1507
[Cu] Atualização por classe:150526
[Lr] Data última revisão:
150526
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:150527
[St] Status:MEDLINE


  3 / 28 MEDLINE  
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[PMID]:25792013
[Au] Autor:Rofiee MS; Yusof MI; Abdul Hisam EE; Bannur Z; Zakaria ZA; Somchit MN; Teh LK; Salleh MZ
[Ad] Endereço:Integrative Pharmacogenomics Institute (iPROMISE), Universiti Teknologi MARA, Puncak Alam Campus, Bandar Puncak Alam, 42300 Selangor, Malaysia.
[Ti] Título:Isolating the metabolic pathways involved in the hepatoprotective effect of Muntingia calabura against CCl4-induced liver injury using LC/MS Q-TOF.
[So] Source:J Ethnopharmacol;166:109-18, 2015 May 26.
[Is] ISSN:1872-7573
[Cp] País de publicação:Ireland
[La] Idioma:eng
[Ab] Resumo:ETHNOPHARMACOLOGICAL RELEVANCE: Muntingia calabura L. has been used in Southeast Asia and tropical America as antipyretic, antiseptic, analgesic, antispasmodic and liver tonic. This study aims to determine the acute toxicity and the metabolic pathways involved in the hepatoprotective mechanism of M. calabura. MATERIALS AND METHODS: CCl4-induced hepatotoxic rat model was developed and a dose dependent effect of M. calabura was conducted. Body weight, food and water consumption were measured every day and rats were sacrificed to collect the serum samples at the end of the 10-days treatment. Liquid chromatography-mass spectrometry quadrapole time of flight (LC/MS-QTOF) combined with principal component analysis (PCA) were used to determine differentially expressed metabolites due to treatment with CCl4 and M. calabura extracts. Metabolomics Pathway Analysis (MetPA) was used for analysis and visualization of pathways involved. RESULTS: Body weight, food and water consumption were significantly decreased and histopathological study revealed steatosis in CCl4-induced rats. PCA score plots show distinct separation in the metabolite profiles of the normal group, CCl4-treated group and extract of M. calabura (MCME) pre-treated groups. Biomarkers network reconstruction using MetPA had identified 2 major pathways which were involved in the protective mechanism of MCME. These include the (i) biosynthesis of the primary bile acid, (ii) metabolism of arachidonic acid. CONCLUSION: This study has successfully isolated 2 major pathways involved in the hepatoprotecive effect of MCME against CCl4-induced liver injury using the LC/MS Q-TOF metabolomics approach. The involvement of archidonic acid and purine metabolism in hepatoprotection has not been reported previously and may provide new therapeutic targets and/or options for the treatment of liver injury.
[Mh] Termos MeSH primário: Doença Hepática Induzida por Substâncias e Drogas/tratamento farmacológico
Elaeocarpaceae/química
Redes e Vias Metabólicas/efeitos dos fármacos
Extratos Vegetais/farmacologia
Substâncias Protetoras/farmacologia
Tiliaceae/química
[Mh] Termos MeSH secundário: Animais
Biomarcadores/metabolismo
Peso Corporal/efeitos dos fármacos
Tetracloreto de Carbono/farmacologia
Doença Hepática Induzida por Substâncias e Drogas/metabolismo
Cromatografia Líquida/métodos
Masculino
Espectrometria de Massas/métodos
Metabolômica/métodos
Ratos
Ratos Sprague-Dawley
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Biomarkers); 0 (Plant Extracts); 0 (Protective Agents); CL2T97X0V0 (Carbon Tetrachloride)
[Em] Mês de entrada:1601
[Cu] Atualização por classe:161125
[Lr] Data última revisão:
161125
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:150321
[St] Status:MEDLINE


  4 / 28 MEDLINE  
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[PMID]:24910899
[Au] Autor:Ekuadzi E; Dickson RA; Fleischer TC; Amponsah IK; Pistorius D; Oberer L
[Ad] Endereço:a Department of Pharmacognosy , Kwame Nkrumah University of Science and Technology , Kumasi , Ghana.
[Ti] Título:Chemical constituents from Gouania longipetala and Glyphaea brevis.
[So] Source:Nat Prod Res;28(15):1210-3, 2014.
[Is] ISSN:1478-6427
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Five compounds were isolated altogether from the two medicinal plants. Glycerol monotricosanoate (1), palmarumycin BG1 (2) and de-O-methyllasiodiplodin (3) were isolated from Gouania longipetala. In addition, epicatechin (4) and its dimer procyanidin B2 (5) were isolated from the stem bark of Glyphaea brevis. Their structures were elucidated by using spectroscopic experiments. They exhibited radical scavenging and moderate antibacterial effects.
[Mh] Termos MeSH primário: Antibacterianos/isolamento & purificação
Depuradores de Radicais Livres/isolamento & purificação
Plantas Medicinais/química
Rhamnaceae/química
Tiliaceae/química
[Mh] Termos MeSH secundário: Antibacterianos/química
Antibacterianos/farmacologia
Biflavonoides/química
Biflavonoides/isolamento & purificação
Catequina/química
Catequina/isolamento & purificação
Depuradores de Radicais Livres/química
Depuradores de Radicais Livres/farmacologia
Macrolídeos/química
Macrolídeos/isolamento & purificação
Estrutura Molecular
Casca de Planta/química
Proantocianidinas/química
Proantocianidinas/isolamento & purificação
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Anti-Bacterial Agents); 0 (Biflavonoids); 0 (Free Radical Scavengers); 0 (Macrolides); 0 (Proanthocyanidins); 0 (de-O-methyllasiodiplodin); 29106-49-8 (procyanidin B2); 8R1V1STN48 (Catechin)
[Em] Mês de entrada:1411
[Cu] Atualização por classe:140701
[Lr] Data última revisão:
140701
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:140610
[St] Status:MEDLINE
[do] DOI:10.1080/14786419.2014.921685


  5 / 28 MEDLINE  
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[PMID]:24354177
[Au] Autor:Kaennakam S; Sichaem J; Khumkratok S; Siripong P; Tip-pyang S
[Ad] Endereço:Natural Products Research Unit, Department of Chemistry, Faculty of Science, Chulalongkorn University, Bangkok 10330, Thailand.
[Ti] Título:A new taraxerol derivative from the roots of Microcos tomentosa.
[So] Source:Nat Prod Commun;8(10):1371-2, 2013 Oct.
[Is] ISSN:1934-578X
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:A new 3beta-O-vanilloyl-taraxerol, microcisin (1) and eight known compounds, 3beta-taraxerol acetate (2), 3beta-taraxerol (3), cholest-4-en-3-one (4), cholest-4-en-6beta-ol-3-one (5), beta-sitosterol (6), 7-hydroxycadalene (7), mellein (8) and vanillin (9), were isolated from the roots of Microcos tomentosa. The structures were determined by extensive analysis of their spectroscopic data. All isolated compounds were evaluated for their cytotoxicity against KB and HeLa cells.
[Mh] Termos MeSH primário: Ácido Oleanólico/análogos & derivados
Tiliaceae/química
[Mh] Termos MeSH secundário: Ensaios de Seleção de Medicamentos Antitumorais
Células HeLa
Seres Humanos
Células KB
Ácido Oleanólico/química
Ácido Oleanólico/isolamento & purificação
Raízes de Plantas/química
Plantas Medicinais/química
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (3beta-O-vanilloyl-taraxerol); 6SMK8R7TGJ (Oleanolic Acid); A32778O852 (taraxerol)
[Em] Mês de entrada:1402
[Cu] Atualização por classe:131220
[Lr] Data última revisão:
131220
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:131221
[St] Status:MEDLINE


  6 / 28 MEDLINE  
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[PMID]:23233503
[Au] Autor:Pinho DB; Firmino AL; Ferreira-Junior WG; Pereira OL
[Ad] Endereço:Departamento de Fitopatologia, Universidade Federal de Viçosa, Minas Gerais, Brazil.
[Ti] Título:New Meliolaceae from the Brazilian Atlantic forest 2: species on host families Annonaceae, Cecropiaceae, Meliaceae, Piperaceae, Rubiaceae, Rutaceae and Tiliaceae.
[So] Source:Mycologia;105(3):697-711, 2013 May-Jun.
[Is] ISSN:0027-5514
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Continuing the study of black mildews in fragments of the Atlantic forest, three new species and five new records are described herein. Irenopsis luheae-grandiflorae, Meliola vicosensis and Meliola xylopia-sericiae are new species. Cecropia hololeuca, Piper gaudichaudianum and Trichilia lepidota are new hosts for Asteridiella leucosykeae, Asteridiella glabroides and Meliola trichiliae respectively. Asteridiella obesa and Meliola psychotriae var. chiococcae are reported for the first time from Brazil. The new species are described and illustrated based on light and scanning electron microscopy and tables with main characteristics of morphologically similar specimens with species collected in Viçosa are provided. Other species belonging to Meliolaceae collected on hosts belonging to the Annonaceae, Meliaceae and Tiliaceae in Brazil also were studied.
[Mh] Termos MeSH primário: Doenças das Plantas/microbiologia
Saccharomycetales/classificação
Árvores/microbiologia
[Mh] Termos MeSH secundário: Annonaceae/microbiologia
Brasil
Meliaceae/microbiologia
Piperaceae/microbiologia
Rubiaceae/microbiologia
Rutaceae/microbiologia
Saccharomycetales/isolamento & purificação
Saccharomycetales/ultraestrutura
Tiliaceae/microbiologia
Urticaceae/microbiologia
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Em] Mês de entrada:1307
[Cu] Atualização por classe:171116
[Lr] Data última revisão:
171116
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:121213
[St] Status:MEDLINE
[do] DOI:10.3852/12-163


  7 / 28 MEDLINE  
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[PMID]:22484311
[Au] Autor:Liao HR; Chen JJ; Chien YH; Lin SZ; Lin S; Tseng CP
[Ad] Endereço:Graduate Institute of Natural Products, College of Medicine, Chang Gung University, Tao-Yuan, Taiwan. liaoch@mail.cgu.edu.tw
[Ti] Título:5-Hydroxy-7-methoxyflavone inhibits N-formyl-L-methionyl-L-leucyl-L-phenylalanine-induced superoxide anion production by specific modulate membrane localization of Tec with a PI3K independent mechanism in human neutrophils.
[So] Source:Biochem Pharmacol;84(2):182-91, 2012 Jul 15.
[Is] ISSN:1873-2968
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Respiratory burst mediates crucial bactericidal mechanism in neutrophils. However, undesirable respiratory burst leads to pathological inflammation and tissue damage. This study investigates the effect and the underlying mechanism of 5-hydroxy-7-methoxyflavone (MCL-1), a lignan extracted from the leaves of Muntingia calabura L. (Tiliaceae), on N-formyl-L-methionyl-L-leucyl-L-phenylalanine (fMLP)-induced respiratory burst and cathepsin G release in human neutrophils. Signaling pathways regulated by MCL-1 to oppose fMLP-induced respiratory burst were evaluated by membrane localization of Tec induced by fMLP and by immunoblotting analysis of downstream phosphorylation targets of Tec. Briefly, MCL-1 specific inhibited fMLP-induced superoxide anion production in a concentration-dependent (IC(50)=0.16±0.01 µM) and Tec kinase-dependent manner, however, MCL-1 did not affect fMLP-induced cathepsin G release. Further, MCL-1 suppressed fMLP-induced Tec translocation from the cytosol to the inner leaflet of the plasma membrane, and subsequently activation of phospholipase Cγ2 (PLCγ2). Moreover, MCL-1 attenuated PLCγ2 activity and intracellular calcium concentration notably through extracellular calcium influx. Consequently, fMLP-induced phosphorylation of protein kinase C (PKC) and membrane localization of p47(phox) were decreased by MCL-1 in a Tec-dependent manner, while the phosphorylation of extracellular signal-regulated kinase (ERK), p38, AKT and Src tyrosine kinase family remained unaffected. In addition, MCL-1 neither inhibited NADPH oxidase activity nor increased cyclicAMP levels. MCL-1 specific opposes fMLP-mediated respiratory burst by inhibition of membrane localization of Tec and subsequently interfered with the activation of PLCγ2, protein kinase C, and p47(phox).
[Mh] Termos MeSH primário: Flavonoides/farmacologia
N-Formilmetionina Leucil-Fenilalanina/farmacologia
Neutrófilos/efeitos dos fármacos
Fosfatidilinositol 3-Quinases/metabolismo
Proteínas Tirosina Quinases/metabolismo
Superóxidos/metabolismo
[Mh] Termos MeSH secundário: Adulto
Cálcio/metabolismo
Catepsina G/metabolismo
AMP Cíclico/metabolismo
Relação Dose-Resposta a Droga
Ativação Enzimática/efeitos dos fármacos
Seres Humanos
NADPH Oxidases/metabolismo
Neutrófilos/metabolismo
Fosfolipase C gama/metabolismo
Fosforilação
Transporte Proteico/efeitos dos fármacos
Proteínas Proto-Oncogênicas c-hck/metabolismo
Tiliaceae/química
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (5-hydroxy-7-methoxyflavone); 0 (Flavonoids); 11062-77-4 (Superoxides); 59880-97-6 (N-Formylmethionine Leucyl-Phenylalanine); E0399OZS9N (Cyclic AMP); EC 1.6.3.- (NADPH Oxidases); EC 2.7.1.- (Phosphatidylinositol 3-Kinases); EC 2.7.1.- (Tec protein-tyrosine kinase); EC 2.7.10.1 (Protein-Tyrosine Kinases); EC 2.7.10.2 (HCK protein, human); EC 2.7.10.2 (Proto-Oncogene Proteins c-hck); EC 3.1.4.3 (Phospholipase C gamma); EC 3.4.21.20 (CTSG protein, human); EC 3.4.21.20 (Cathepsin G); SY7Q814VUP (Calcium)
[Em] Mês de entrada:1208
[Cu] Atualização por classe:171116
[Lr] Data última revisão:
171116
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:120410
[St] Status:MEDLINE
[do] DOI:10.1016/j.bcp.2012.03.015


  8 / 28 MEDLINE  
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[PMID]:22619925
[Au] Autor:Nuaeissara S; Kondo S; Itharat A
[Ad] Endereço:Faculty of Medicine, Thammasat University, Pathumthani, Thailand.
[Ti] Título:Antimicrobial activity of the extracts from Benchalokawichian remedy and its components.
[So] Source:J Med Assoc Thai;94 Suppl 7:S172-7, 2011 Dec.
[Is] ISSN:0125-2208
[Cp] País de publicação:Thailand
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Infectious diseases cause serious health problems worldwide due to multiresistant bacterial strains. Thai traditional formula such as Benchalokawichian remedy has been used to relieve fever, common cold and influenza. The remedy has been scientifically proved for antipyretic and antiseptic activities. However; the remedy and its components have not been fully studied for antimicrobial activity against pathogenic bacteria. OBJECTIVE: To determine antimicrobial activity of extracts from Benchalokawichian remedy and its components against clinical isolates by disk diffusion method. MATERIAL AND METHOD: The bacterial strains used in the present study were clinical isolates from Thammasat Hospital, Thailand. The ethanolic and water extracts of Benchalokawichian remedy and its components were screened for antimicrobial activity. The tests were performed in triplicate. The results were recorded by measuring diameter of growth inhibition zone. Means +/- SD of the obtained results were calculated. RESULTS: The results of antimicrobial activity demonstrated that the ethanolic extracts of Benchalokawichian remedy and its components were effective against Candida albicans, Gram positive and Gram negative bacteria except some isolates. Tiliacora triandra and Clerodendrum petasites exhibited the most effective antimicrobial activity among other ethanolic extracts. The water extracts of Capparis micracantha, Tiliacora triandra and Harrisonia perforata were able to inhibit the tested strains. Both etahnolic and water extracts of Tiliacora triandra were the only one component of Benchalokawichian remedy that could inhibit the growth of C. albicans. CONCLUSION: The present study provides basic knowledge of the antimicrobial activity of Benchalokawichian remedy and its components. Tiliacora triandra and Clerodendrum petasites were the most effective antimicrobial activity among other ethanolic extracts. They are potential candidates to produce medicinal formula for alternative medicine. Further study on minimum inhibitory concentration and minimum bactericidal concentration assay will be carried out in order to obtain more detailed insightful knowledge to develop medicinal products for treatment of bacterial infection and other infectious diseases.
[Mh] Termos MeSH primário: Bactérias Gram-Negativas/efeitos dos fármacos
Bactérias Gram-Positivas/efeitos dos fármacos
Medicina Tradicional
Fitoterapia
Extratos Vegetais/farmacologia
[Mh] Termos MeSH secundário: Capparis
Clerodendrum
Ficus
Seres Humanos
Testes de Sensibilidade Microbiana
Simaroubaceae
Tailândia
Tiliaceae
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Plant Extracts)
[Em] Mês de entrada:1208
[Cu] Atualização por classe:120524
[Lr] Data última revisão:
120524
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:120525
[St] Status:MEDLINE


  9 / 28 MEDLINE  
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[PMID]:20957954
[Au] Autor:Mangan SA; Herre EA; Bever JD
[Ad] Endereço:Department of Biology, Indiana University, Bloomington, Indiana 47405, USA. smangan37@gmail.com
[Ti] Título:Specificity between Neotropical tree seedlings and their fungal mutualists leads to plant-soil feedback.
[So] Source:Ecology;91(9):2594-603, 2010 Sep.
[Is] ISSN:0012-9658
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:A growing body of evidence obtained largely from temperate grassland studies suggests that feedbacks occurring between plants and their associated soil biota are important to plant community assemblage. However, few studies have examined the importance of soil organisms in driving plant-soil feedbacks in forested systems. In a tropical forest in central Panama, we examined whether interactions between tree seedlings and their associated arbuscular mycorrhizal fungi (AMF) lead to plant-soil feedback. Specifically, do tropical seedlings modify their own AMF communities in a manner that either favors or inhibits the next cohort of conspecific seedlings (i.e., positive or negative feedback, respectively)? Seedlings of two shade-tolerant tree species (Eugenia nesiotica, Virola surinamensis) and two pioneer tree species (Luehea seemannii, Apeiba aspera) were grown in pots containing identical AMF communities composed of equal amounts of inoculum of six co-occurring AMF species. The different AMF-host combinations were all exposed to two light levels. Under low light (2% PAR), only two of the six AMF species sporulated, and we found that host identity did not influence composition of AMF spore communities. However, relative abundances of three of the four AMF species that produced spores were influenced by host identity when grown under high light (20% PAR). Furthermore, spores of one of the AMF species, Glomus geosporum, were common in soils of Luehea and Eugenia but absent in soils of Apeiba and Virola. We then conducted a reciprocal experiment to test whether AMF communities previously modified by Luehea and Apeiba differentially affected the growth of conspecific and heterospecific seedlings. Luehea seedling growth did not differ between soils containing AMF communities modified by Luehea and Apeiba. However, Apeiba seedlings were significantly larger when grown with Apeiba-modified AMF communities, as compared to Apeiba seedlings grown with Luehea-modifed AMF communities. Our experiments suggest that interactions between tropical trees and their associated AMF are species-specific and that these interactions may shape both tree and AMF communities through plant-soil feedback.
[Mh] Termos MeSH primário: Fungos/fisiologia
Plântulas/microbiologia
Solo
Simbiose/fisiologia
Árvores/microbiologia
[Mh] Termos MeSH secundário: Ecossistema
Luz
Myristicaceae/microbiologia
Myrtaceae/microbiologia
Esporos Fúngicos
Tiliaceae/microbiologia
Fatores de Tempo
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T; RESEARCH SUPPORT, U.S. GOV'T, NON-P.H.S.
[Nm] Nome de substância:
0 (Soil)
[Em] Mês de entrada:1011
[Cu] Atualização por classe:171116
[Lr] Data última revisão:
171116
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:101021
[St] Status:MEDLINE


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[PMID]:20093175
[Au] Autor:Mbosso EJ; Ngouela S; Nguedia JC; Beng VP; Rohmer M; Tsamo E
[Ad] Endereço:Laboratoire de Substances Naturelles et Synthèse Organique, Département de Chimie Organique, Faculté des Sciences, Université de Yaoundé I, BP 812 Yaoundé, Cameroon.
[Ti] Título:In vitro antimicrobial activity of extracts and compounds of some selected medicinal plants from Cameroon.
[So] Source:J Ethnopharmacol;128(2):476-81, 2010 Mar 24.
[Is] ISSN:1872-7573
[Cp] País de publicação:Ireland
[La] Idioma:eng
[Ab] Resumo:AIM OF THE STUDY: Seven extracts and eight compounds from four selected Cameroonian medicinal plants, Solanecio mannii Hook f. (Asteraceae), Monodora myristica Dunal (Annonaceae), Albizia gummifera (J.F. Gmel) C.A. Smith (Fabaceae/Mimosoideae) and Glyphaea brevis (Spreng) Monachino (Tiliaceae), traditionally used for the treatment of hepatitis, parasites and other infectious diseases, were tested in vitro for their antimicrobial activity against Gram-positive (5 species) and Gram-negative (4 species) bacteria species and pathogenic yeasts (2 Candida species), to establish whether or not they have antimicrobial activity and to validate scientifically their use in traditional medicine. MATERIALS AND METHODS: The agar disc diffusion and the microbroth dilution methods were used to determine the zone of inhibition between the edge of the filter paper and the edge of the inhibition area (IZ) and the minimal inhibitory concentration (MIC) respectively. RESULTS: The most active extracts against Candida albicans and Candida krusei were respectively the cyclohexane extract from the fruits of Monodora myristica and the ethyl acetate extract from the stem bark of Albizia gummifera (MIC=6.3 microg/ml for both extracts). The lowest MIC value (1.6 microg/ml) for purified compounds was obtained on Candida albicans with a mixture of linear aliphatic primary alcohols (n-C24H50O to n-C30H62O), with n-hexacosanol (1b) as major compound and mixture of fatty acid esters of diunsaturated linear 1,2-diols (6). CONCLUSION: These results afford ground informations for the potential use of the crude extracts of these species as well as of some of the isolated compounds in bacterial and fungal infections.
[Mh] Termos MeSH primário: Anti-Infecciosos/farmacologia
Bactérias/efeitos dos fármacos
Micoses/tratamento farmacológico
Plantas Medicinais/química
Leveduras/efeitos dos fármacos
[Mh] Termos MeSH secundário: Albizzia
Annonaceae
Anti-Infecciosos/isolamento & purificação
Camarões
Candida/efeitos dos fármacos
Candida albicans/efeitos dos fármacos
Formas de Dosagem
Álcoois Graxos/química
Medicina Tradicional
Testes de Sensibilidade Microbiana/métodos
Tiliaceae
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Anti-Infective Agents); 0 (Dosage Forms); 0 (Fatty Alcohols); M7SD300NNB (1-hexacosanol)
[Em] Mês de entrada:1007
[Cu] Atualização por classe:121115
[Lr] Data última revisão:
121115
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:100123
[St] Status:MEDLINE
[do] DOI:10.1016/j.jep.2010.01.017



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