Base de dados : MEDLINE
Pesquisa : B01.650.940.800.575.912.250.970.199 [Categoria DeCS]
Referências encontradas : 31 [refinar]
Mostrando: 1 .. 10   no formato [Detalhado]

página 1 de 4 ir para página            

  1 / 31 MEDLINE  
              next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:27777106
[Au] Autor:Pereira-Torres D; Gonçalves AT; Ulloa V; Martínez R; Carrasco H; Olea AF; Espinoza L; Gallardo-Escárate C; Astuya A
[Ad] Endereço:Laboratory of Cell Culture and Marine Genomics, Department of Oceanography and COPAS Sur-Austral, University of Concepción, Casilla 160-C, Concepción, Chile.
[Ti] Título:In vitro modulation of Drimys winteri bark extract and the active compound polygodial on Salmo salar immune genes after exposure to Saprolegnia parasitica.
[So] Source:Fish Shellfish Immunol;59:103-108, 2016 Dec.
[Is] ISSN:1095-9947
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:The rapid development of the aquaculture industry has global concerns with health management and control strategies to prevent and/or treat diseases and increase sustainability standards. Saprolegniosis is a disease caused by Saprolegnia parasitica, and is characterized by promoting an immunosuppression in the host. This study evaluated in vitro the extract and one active compound (polygodial) of Drimys winteri, a Chilean medicinal tree as a potential early immunostimulatory aid in Saprolegniosis control. Atlantic salmon (Salmo salar) head kidney cells (ASK-1) were incubated with both extract and pure polygodial before exposure to S. parasitica mycelium, and the expression of the immune-related genes interleukin 1ß (IL-1ß), interferon α (IFNα), and major histocompatibility complex II (MHCII) was evaluated. Both evidenced immunomodulatory capacities by increasing gene expressions. This immunomodulation related to a mitigatory action counteracting the immunosuppressing effects of S. parasitica. Despite that most immune-related genes were up-regulated, the down-regulation of MHCII, characteristic of S. parasitica infection, was lessened by pre-incubation with the compounds. This study provides the first insight on the potential of D. winteri bark extract as a possible immunomodulatory and defensive strategy against this oomycete infection in fish.
[Mh] Termos MeSH primário: Drimys/química
Doenças dos Peixes/imunologia
Infecção/veterinária
Extratos Vegetais/farmacologia
Salmo salar
Sesquiterpenos/farmacologia
[Mh] Termos MeSH secundário: Ração Animal/análise
Animais
Dieta/veterinária
Doenças dos Peixes/microbiologia
Infecção/imunologia
Infecção/microbiologia
Casca de Planta/química
Extratos Vegetais/química
Saprolegnia/fisiologia
Sesquiterpenos/química
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Plant Extracts); 0 (Sesquiterpenes); 5FAF7T66M7 (polygodial)
[Em] Mês de entrada:1703
[Cu] Atualização por classe:171203
[Lr] Data última revisão:
171203
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161106
[St] Status:MEDLINE


  2 / 31 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:27645309
[Au] Autor:Barrosa KH; Mecchi MC; Rando DG; Ferreira AJ; Sartorelli P; Valle MM; Bordin S; Caperuto LC; Lago JH; Lellis-Santos C
[Ad] Endereço:Instituto de Ciências Ambientais, Químicas e Farmacêuticas, Universidade Federal de São Paulo, 09972-270, São Paulo, Brazil.
[Ti] Título:Polygodial, a sesquiterpene isolated from Drimys brasiliensis (Winteraceae), triggers glucocorticoid-like effects on pancreatic ß-cells.
[So] Source:Chem Biol Interact;258:245-56, 2016 Oct 25.
[Is] ISSN:1872-7786
[Cp] País de publicação:Ireland
[La] Idioma:eng
[Ab] Resumo:Despite its common use, the synthetic glucocorticoid dexamethasone can cause several adverse effects, such as diabetes and insulin-related metabolic impairment. Thus, research on molecules that could provide the same anti-inflammatory response with milder side effects is constant. In this work the anti-inflammatory activity of the natural sesquiterpene polygodial, extracted from the endemic Brazilian plant Drimys brasiliensis Miers (Winteraceae), was investigated. Employing a pancreatic ß-cell model (INS 1E), the effect of polygodial on signaling pathways is similar to that caused by dexamethasone - both increased MKP1 and decreased ERK1/2 expression in a dose-response and time-dependent manner. Relating to such finding, nuclear translocation of the glucocorticoid receptor was also discovered to be induced by the sesquiterpene. Molecular modeling results indicated that polygodial was capable of docking to the glucocorticoid receptor, but presented preference for the Arg611 binding site rather than Thr739 when set to bind freely inside the pocket. At last, fragmentation of DNA was verified as consequence of sesquiterpene-induced cell death. Altogether, our results suggest that, like dexamethasone, polygodial interacts the glucocorticoid receptor ligand binding domain but create fewer ligand-protein interactions at the site, yielding a weaker effector response. Such property provides an advantage when regarding the adverse effects resulting from stronger affinity ligands of the glucocorticoid receptor, such as in the case of the current standard dexamethasone-based treatment. This aspect, also, turns polygodial an interesting hit compound to the development of new drugs based on its backbone structure providing less harmful anti-inflammatory treatments.
[Mh] Termos MeSH primário: Dexametasona/farmacologia
Drimys/química
Glucocorticoides/farmacologia
Células Secretoras de Insulina/metabolismo
Sesquiterpenos/isolamento & purificação
Sesquiterpenos/farmacologia
[Mh] Termos MeSH secundário: Animais
Sítios de Ligação
Linhagem Celular Tumoral
Núcleo Celular/efeitos dos fármacos
Núcleo Celular/metabolismo
Sobrevivência Celular/efeitos dos fármacos
Fragmentação do DNA/efeitos dos fármacos
Dexametasona/química
Células Secretoras de Insulina/efeitos dos fármacos
Camundongos
Simulação de Acoplamento Molecular
Transporte Proteico/efeitos dos fármacos
Receptores de Glucocorticoides/metabolismo
Sesquiterpenos/química
Transdução de Sinais/efeitos dos fármacos
Fatores de Tempo
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Glucocorticoids); 0 (Receptors, Glucocorticoid); 0 (Sesquiterpenes); 5FAF7T66M7 (polygodial); 7S5I7G3JQL (Dexamethasone)
[Em] Mês de entrada:1701
[Cu] Atualização por classe:170131
[Lr] Data última revisão:
170131
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160921
[St] Status:MEDLINE


  3 / 31 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:27095358
[Au] Autor:Fratoni E; Claudino VD; Yunes RA; Franchi GC; Nowill AE; Filho VC; Monache FD; Malheiros A
[Ad] Endereço:Programa de Pós-Graduação em Ciências Farmacêuticas e Núcleo de Investigações Químico-Farmacêuticas, Universidade do Vale do Itajaí - UNIVALI, Itajaí, SC, CEP 88302-202, Brazil.
[Ti] Título:Further drimane sesquiterpenes from Drimys brasiliensis stem barks with cytotoxic potential.
[So] Source:Naunyn Schmiedebergs Arch Pharmacol;389(7):791-7, 2016 Jul.
[Is] ISSN:1432-1912
[Cp] País de publicação:Germany
[La] Idioma:eng
[Ab] Resumo:Drimys brasiliensis Miers (Winteraceae) is used in folk medicine for the treatment of cancer. Its anti-tumor activity has been demonstrated in vitro models using extracts and isolated compounds. This study investigates the cytotoxic effects of stem bark extracts of D. brasiliensis as well as isolated compounds that may be responsible for the activitys and evaluates them in leukemia cells. The stem bark extract were subjected to column chromatography, and the structures of compounds were elucidated based on spectroscopic methods by using NMR and infrared spectroscopy and GC/MS. The cytotoxicity of the isolated compounds was evaluated in chronic myeloid (K562) and acute B lymphoblastic (Nalm6) leukemia cells using tetrazolium assay (MTT). Two new compounds were isolated 1ß-O-p-methoxy-E-cinnamoyl-5α-keto-11α-enol-albicanol (1a) and the isomer 1ß-O-p-methoxy-E-cinnamoyl-5α-keto-11ß-enol-albicanol (1b) and 1ß-O-p-methoxy-E-cinnamoyl-isodrimeninol (2). The known compounds polygonal acid (3a) and the isomer isopolygonal acid (3b), fuegin (4a) and the isomer epifuegin (4b), the mixture drimanial (5) and 1ß-O-(p-methoxy-E-cinnamoyl)-6α-hydroxypolygodial (6) were also isolated. The drimanes (1-4) and drimanial (5), 1ß-(p-coumaroyloxy)-polygodial (7), 1ß-(p-methoxycinnamoyl)-polygodial (8), and polygodial (9) isolated previously were assessed in tumor cells. The IC50 values were between 3.56 and 128.91 µM. 1-ß-(p-cumaroiloxi)-polygodial showed the best result with IC50 8.18 and 3.56 µM by K562 and Nalm6, respectively. The chloroform extract of the stem bark of D. brasiliensis is a great source of drimane sesquiterpenes. Our experimental data suggest that drimanes are responsible for cytotoxicity activity demonstrated by this species, especially those with the aldehyde group linked to carbons C-11 and C-12.
[Mh] Termos MeSH primário: Antineoplásicos Fitogênicos/farmacologia
Drimys/química
Leucemia Mielogênica Crônica BCR-ABL Positiva/tratamento farmacológico
Leucemia-Linfoma Linfoblástico de Células Precursoras B/tratamento farmacológico
Sesquiterpenos/farmacologia
[Mh] Termos MeSH secundário: Antineoplásicos Fitogênicos/química
Antineoplásicos Fitogênicos/isolamento & purificação
Sobrevivência Celular/efeitos dos fármacos
Relação Dose-Resposta a Droga
Cromatografia Gasosa-Espectrometria de Massas
Seres Humanos
Concentração Inibidora 50
Células K562
Leucemia Mielogênica Crônica BCR-ABL Positiva/patologia
Espectroscopia de Ressonância Magnética
Estrutura Molecular
Fitoterapia
Casca de Planta/química
Caules de Planta/química
Plantas Medicinais
Leucemia-Linfoma Linfoblástico de Células Precursoras B/patologia
Sesquiterpenos/química
Sesquiterpenos/isolamento & purificação
Espectrofotometria Infravermelho
Relação Estrutura-Atividade
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Antineoplastic Agents, Phytogenic); 0 (Sesquiterpenes); 0 (drimane)
[Em] Mês de entrada:1702
[Cu] Atualização por classe:170920
[Lr] Data última revisão:
170920
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160421
[St] Status:MEDLINE
[do] DOI:10.1007/s00210-016-1241-7


  4 / 31 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:25836288
[Au] Autor:Paz C; Burgos V; Suarez S; Baggio R
[Ad] Endereço:Departamento de Ciencias Químicas y Recursos Naturales, Facultad de Ingeniería, Universidad de La Frontera, Temuco, Chile.
[Ti] Título:A monoclinic form of dendocarbin A: a borderline case of one-dimensional isostructural polymorphism.
[So] Source:Acta Crystallogr C Struct Chem;71(Pt 4):294-7, 2015 Apr.
[Is] ISSN:2053-2296
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:The title compound, dendocarbin A [systematic name: (1R,5aS,9aS,9bR)-1-hydroxy-6,6,9a-trimethyldodecahydronaphtho[1,2-c]furan-3-one], C15H22O3, is a sesquiterpene lactone isolated from Drimys winteri var chilensis. The monoclinic phase described herein displays an identical molecular structure to the orthorhombic phase that we reported previously [Paz Robles et al. (2014). Acta Cryst. C70, 1007-1010], while varying significantly in chain pitch, and can thus be considered as a borderline case of one-dimensional isostructural polymorphism.
[Mh] Termos MeSH primário: Drimys/química
Lactonas/química
Sesquiterpenos/química
[Mh] Termos MeSH secundário: Cristalização
Lactonas/isolamento & purificação
Estrutura Molecular
Sesquiterpenos/isolamento & purificação
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Lactones); 0 (Sesquiterpenes); 0 (dendocarbin A)
[Em] Mês de entrada:1507
[Cu] Atualização por classe:151231
[Lr] Data última revisão:
151231
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:150404
[St] Status:MEDLINE
[do] DOI:10.1107/S2053229615004994


  5 / 31 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:25716877
[Au] Autor:Eller CB; Burgess SS; Oliveira RS
[Ad] Endereço:Department of Plant Biology, Institute of Biology, University of Campinas - UNICAMP, CP6109, Campinas, SP, Brazil.
[Ti] Título:Environmental controls in the water use patterns of a tropical cloud forest tree species, Drimys brasiliensis (Winteraceae).
[So] Source:Tree Physiol;35(4):387-99, 2015 Apr.
[Is] ISSN:1758-4469
[Cp] País de publicação:Canada
[La] Idioma:eng
[Ab] Resumo:Trees from tropical montane cloud forest (TMCF) display very dynamic patterns of water use. They are capable of downwards water transport towards the soil during leaf-wetting events, likely a consequence of foliar water uptake (FWU), as well as high rates of night-time transpiration (Enight) during drier nights. These two processes might represent important sources of water losses and gains to the plant, but little is known about the environmental factors controlling these water fluxes. We evaluated how contrasting atmospheric and soil water conditions control diurnal, nocturnal and seasonal dynamics of sap flow in Drimys brasiliensis (Miers), a common Neotropical cloud forest species. We monitored the seasonal variation of soil water content, micrometeorological conditions and sap flow of D. brasiliensis trees in the field during wet and dry seasons. We also conducted a greenhouse experiment exposing D. brasiliensis saplings under contrasting soil water conditions to deuterium-labelled fog water. We found that during the night D. brasiliensis possesses heightened stomatal sensitivity to soil drought and vapour pressure deficit, which reduces night-time water loss. Leaf-wetting events had a strong suppressive effect on tree transpiration (E). Foliar water uptake increased in magnitude with drier soil and during longer leaf-wetting events. The difference between diurnal and nocturnal stomatal behaviour in D. brasiliensis could be attributed to an optimization of carbon gain when leaves are dry, as well as minimization of nocturnal water loss. The leaf-wetting events on the other hand seem important to D. brasiliensis water balance, especially during soil droughts, both by suppressing tree transpiration (E) and as a small additional water supply through FWU. Our results suggest that decreases in leaf-wetting events in TMCF might increase D. brasiliensis water loss and decrease its water gains, which could compromise its ecophysiological performance and survival during dry periods.
[Mh] Termos MeSH primário: Atmosfera
Drimys/fisiologia
Ecossistema
Folhas de Planta/fisiologia
Solo
Árvores/fisiologia
Água/fisiologia
[Mh] Termos MeSH secundário: Carbono/metabolismo
Secas
Florestas
Fotossíntese
Caules de Planta
Transpiração Vegetal
Estações do Ano
Clima Tropical
Winteraceae
Xilema/fisiologia
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Soil); 059QF0KO0R (Water); 7440-44-0 (Carbon)
[Em] Mês de entrada:1601
[Cu] Atualização por classe:171116
[Lr] Data última revisão:
171116
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:150227
[St] Status:MEDLINE
[do] DOI:10.1093/treephys/tpv001


  6 / 31 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
PubMed Central Texto completo
Texto completo
[PMID]:25292282
[Au] Autor:López-Sepúlveda P; Takayama K; Greimler J; Crawford DJ; Peñailillo P; Baeza M; Ruiz E; Kohl G; Tremetsberger K; Gatica A; Letelier L; Novoa P; Novak J; Stuessy TF
[Ad] Endereço:Departamento de Botánica, Universidad de Concepción, Casilla 160-C, Concepción, Chile.
[Ti] Título:Progressive migration and anagenesis in Drimys confertifolia of the Juan Fernández Archipelago, Chile.
[So] Source:J Plant Res;128(1):73-90, 2015 Jan.
[Is] ISSN:1618-0860
[Cp] País de publicação:Japan
[La] Idioma:eng
[Ab] Resumo:A common mode of speciation in oceanic islands is by anagenesis, wherein an immigrant arrives and through time transforms by mutation, recombination, and drift into a morphologically and genetically distinct species, with the new species accumulating a high level of genetic diversity. We investigate speciation in Drimys confertifolia, endemic to the two major islands of the Juan Fernández Archipelago, Chile, to determine genetic consequences of anagenesis, to examine relationships among populations of D. confertifolia and the continental species D. winteri and D. andina, and to test probable migration routes between the major islands. Population genetic analyses were conducted using AFLPs and nuclear microsatellites of 421 individuals from 42 populations from the Juan Fernández islands and the continent. Drimys confertifolia shows a wide genetic variation within populations on both islands, and values of genetic diversity within populations are similar to those found within populations of the continental progenitor. The genetic results are compatible with the hypothesis of high levels of genetic variation accumulating within anagenetically derived species in oceanic islands, and with the concept of little or no geographical partitioning of this variation over the landscape. Analysis of the probability of migration within the archipelago confirms colonization from the older island, Robinson Crusoe, to the younger island Alejandro Selkirk.
[Mh] Termos MeSH primário: Drimys/genética
Especiação Genética
Ilhas
[Mh] Termos MeSH secundário: Análise do Polimorfismo de Comprimento de Fragmentos Amplificados
Chile
Variação Genética
Genética Populacional
Geografia
Repetições de Microssatélites/genética
Modelos Biológicos
Filogenia
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Em] Mês de entrada:1601
[Cu] Atualização por classe:170220
[Lr] Data última revisão:
170220
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:141009
[St] Status:MEDLINE
[do] DOI:10.1007/s10265-014-0666-7


  7 / 31 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:25471409
[Au] Autor:Paz Robles C; Mercado D; Suarez S; Baggio R
[Ad] Endereço:Departamento de Ciencias Químicas y Recursos Naturales, Facultad de Ingeniería, Universidad de La Frontera, Temuco, Chile.
[Ti] Título:Two drimane lactones, valdiviolide and 11-epivaldiviolide, in the form of a 1:1 cocrystal obtained from Drimys winteri extracts.
[So] Source:Acta Crystallogr C Struct Chem;70(Pt 12):1112-5, 2014 Dec.
[Is] ISSN:2053-2296
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:A cocrystal, C15H22O3·C15H22O3, (I), obtained from Drimys winteri, is composed of two isomeric drimane sesquiterpene lactones, namely valdiviolide, (Ia), and 11-epivaldiviolide, (Ib), neither of which has been reported in the crystal form. Both diastereoisomers present three chiral centres at sites 5, 10 and 11, with an SSR sequence in (Ia) and an SSS sequence in (Ib). O-H···O hydrogen bonds bind molecules into chains running along [120] and the chains are in turn linked by π-π stacking interactions to define planar weakly interacting arrays parallel to (001).
[Mh] Termos MeSH primário: Drimys/química
Lactonas/química
Sesquiterpenos/química
Sesquiterpenos/síntese química
[Mh] Termos MeSH secundário: Cristalografia por Raios X
Ligações de Hidrogênio
Isomerismo
Lactonas/isolamento & purificação
Estrutura Molecular
Sesquiterpenos/isolamento & purificação
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (11-epivaldiviolide); 0 (Lactones); 0 (Sesquiterpenes); 0 (drimane)
[Em] Mês de entrada:1503
[Cu] Atualização por classe:151231
[Lr] Data última revisão:
151231
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:141205
[St] Status:MEDLINE
[do] DOI:10.1107/S205322961402395X


  8 / 31 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
[PMID]:25412542
[Au] Autor:Marquínez-Casas X
[Ti] Título:[Anatomy and development of stamens and carpels of Drimys granadensis (Winteraceae)].
[Ti] Título:Anatomía y desarrollo de estambres y carpelos en Drimys granadensis (Winteraceae)..
[So] Source:Rev Biol Trop;62(3):1147-59, 2014 Sep.
[Is] ISSN:0034-7744
[Cp] País de publicação:Costa Rica
[La] Idioma:spa
[Ab] Resumo:Winteraceae has long been considered a family with early diversification among angiosperms, with characters such as: flowers with many spirally arranged parts and apocarpic ovary formed by plicated carpels with sessile stigma. In Drimys, the presence or absence of conspicuous glands on the connective of the stamens have been used as a taxonomic character, and it is considered a synapomorphy for the clade including Drimys angustifolia, D. brasiliensis, D. granadensis and D. roraimensis (Northeastern clade); however, the anatomy of stamens and carpels has only been studied in detail for D. winteri (Southwestern clade). In this research, the presence and the structure of glands on the connective of stamens was studied in seven species of the genus from herbarium specimens, and a detailed study of the anatomy and development of stamens and carpels was carried out by scanning electron and optic microscopy in Drimys granadensis. We found similarities between D. granadensis and D. winteri for the following characters: Basic type anther wall formation, secretory tapetum that collapses at maturity, intermediate type microsporogenesis with formation of a transient cell plate in telophase I, ascidiated carpel due to the formation of an adaxial lip during development, stigma closed by interdigitation of epidermal cells. We also determined that the large glands on anther mature connective are originated by an overgrowth of subepidermal oil cells; this character is a Northeastern Drimys clade synapomorphy, while it was absent in both Drimys of Southwestern clade (which includes D. andina, D. confertifolia and D. winteri), and the rest of the Winteraceae. We are proposing the hypothesis that the highly variable enviromental conditions in the tropics where Drimys Northeastern clade is distributed, with a wide range of pollinators, would be associated with the emergence of glandular conspicuously stamens; while, as a prediction to be confirmed, temperated Southwestern clade species, without conspicuous glands, should have a smaller range of visitors and/or pollinators, or even be anemophilous species as Drimys confertifolia.
[Mh] Termos MeSH primário: Drimys
Flores/anatomia & histologia
Flores/crescimento & desenvolvimento
[Mh] Termos MeSH secundário: Drimys/classificação
Drimys/crescimento & desenvolvimento
Drimys/ultraestrutura
Microscopia Eletrônica de Varredura
Polinização
[Pt] Tipo de publicação:ENGLISH ABSTRACT; JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Em] Mês de entrada:1503
[Cu] Atualização por classe:141121
[Lr] Data última revisão:
141121
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:141122
[St] Status:MEDLINE


  9 / 31 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:25370095
[Au] Autor:Paz Robles C; Burgos V; Suarez S; Baggio R
[Ad] Endereço:Departamento de Ciencias Químicas y Recursos Naturales, Facultad de Ingeniería, Universidad de La Frontera, Temuco, Chile.
[Ti] Título:Dendocarbin A: a sesquiterpene lactone from Drimys winteri.
[So] Source:Acta Crystallogr C Struct Chem;70(Pt 11):1007-10, 2014 Nov.
[Is] ISSN:2053-2296
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:The natural compound dendocarbin A, C15H22O3, is a sesquiterpene lactone isolated for the first time from Drimys winteri for var chilensis. The compound crystallizes in the orthorhombic space group P212121 and its X-ray crystal structure confirmed the S/R character of the chiral centres at C-5/C-10 and C-9/C-11, respectively. The α-OH group at C-11 was found to be involved in intermolecular hydrogen bonding, defining chains along the <100> 21 screw axis.
[Mh] Termos MeSH primário: Drimys/química
Sesquiterpenos/química
Sesquiterpenos/isolamento & purificação
[Mh] Termos MeSH secundário: Cristalografia por Raios X
Drimys/metabolismo
Estrutura Molecular
Sesquiterpenos/síntese química
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Sesquiterpenes); 0 (dendocarbin A)
[Em] Mês de entrada:1504
[Cu] Atualização por classe:151231
[Lr] Data última revisão:
151231
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:141106
[St] Status:MEDLINE
[do] DOI:10.1107/S205322961402155X


  10 / 31 MEDLINE  
              first record previous record
seleciona
para imprimir
Fotocópia
Texto completo SciELO Brasil
[PMID]:25119732
[Au] Autor:Mariot A; Mantovani A; Reis MS
[Ad] Endereço:Núcleo de Pesquisas em Florestas Tropicais, Departamento de Fitotecnia, Centro de Ciências Agrárias, Universidade Federal de Santa Catarina, Florianópolis, SC, Brasil.
[Ti] Título:Bark harvesting systems of Drimys brasiliensis Miers in the Brazilian Atlantic rainforest.
[So] Source:An Acad Bras Cienc;86(3):1315-26, 2014 Sep.
[Is] ISSN:1678-2690
[Cp] País de publicação:Brazil
[La] Idioma:eng
[Ab] Resumo:Drimys brasiliensis Miers, locally known as cataia or casca-de-anta, is a native tree species of the Atlantic Rainforest. Its bark is harvested from natural populations. This study examined the recovery capacity of the bark of D. brasiliensis under different bark harvesting methods, as well as the influence of these approaches on its population dynamics and reproductive biology. While none of these treatments resulted in changes in phenological behavior or the rate of increase of diameter at breast height and tree height, the removal of wider bark strips resulted in lower rates of bark recovery and higher rates of insect attack and diseases. Accordingly, the results recommend using strips of bark 2 cm wide and 2 m long, with 4 cm between strips, for effective rates of bark regrowth and for lower susceptibility to insect attack and diseases. From these studies, we concluded that D. brasiliensis has a high potential for sustainable management of its natural populations, demonstrating the possibility of generating an important supplementary income for farmers and contributing to the use and conservation of the Atlantic Rainforest.
[Mh] Termos MeSH primário: Conservação dos Recursos Naturais/métodos
Drimys/crescimento & desenvolvimento
Casca de Planta/crescimento & desenvolvimento
Árvores
[Mh] Termos MeSH secundário: Brasil
Monitoramento Ambiental
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Em] Mês de entrada:1501
[Cu] Atualização por classe:140912
[Lr] Data última revisão:
140912
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:140815
[St] Status:MEDLINE



página 1 de 4 ir para página            
   


Refinar a pesquisa
  Base de dados : MEDLINE Formulário avançado   

    Pesquisar no campo  
1  
2
3
 
           



Search engine: iAH v2.6 powered by WWWISIS

BIREME/OPAS/OMS - Centro Latino-Americano e do Caribe de Informação em Ciências da Saúde