Base de dados : MEDLINE
Pesquisa : B03.300.390.650 [Categoria DeCS]
Referências encontradas : 55 [refinar]
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[PMID]:28284153
[Au] Autor:Schlüter-Vorberg L; Knopp G; Cornel P; Ternes T; Coors A
[Ad] Endereço:ECT Oekotoxikologie GmbH, 65439, Flörsheim, Germany; Department Aquatic Ecotoxicology, Goethe Universität Frankfurt, 60438, Frankfurt am Main, Germany. Electronic address: l.vorberg@ect.de.
[Ti] Título:Survival, reproduction, growth, and parasite resistance of aquatic organisms exposed on-site to wastewater treated by advanced treatment processes.
[So] Source:Aquat Toxicol;186:171-179, 2017 May.
[Is] ISSN:1879-1514
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:Advanced wastewater treatment technologies are generally known to be an effective tool for reducing micropollutant discharge into the aquatic environment. Nevertheless, some processes such as ozonation result in stable transformation products with often unknown toxicity. In the present study, whole effluents originating from nine different steps of advanced treatment combinations were compared for their aquatic toxicity. Assessed endpoints were survival, growth and reproduction of Lumbriculus variegatus, Daphnia magna and Lemna minor chronically exposed in on-site flow-through tests based on standard guidelines. The treatment combinations were activated sludge treatment followed by ozonation with subsequent filtration by granular activated carbon or biofilters and membrane bioreactor treatment of raw wastewater followed by ozonation. Additionally, the impact of treated wastewater on the immune response of invertebrates was investigated by challenging D. magna with a bacterial endoparasite. Conventionally treated wastewater reduced reproduction of L. variegatus by up to 46%, but did not affect D. magna and L. minor with regard to survival, growth, reproduction and parasite resistance. Instead, parasite susceptibility was significantly reduced in D. magna exposed to conventionally treated as well as ozonated wastewater in comparison to D. magna exposed to the medium control. None of the three test organisms provided clear evidence that wastewater ozonation leads to increased aquatic toxicity. Rather than to the presence of toxic transformation products, the affected performance of L. variegatus could be linked to elevated concentrations of ammonium and nitrite that likely resulted from treatment failures.
[Mh] Termos MeSH primário: Organismos Aquáticos/crescimento & desenvolvimento
Organismos Aquáticos/fisiologia
Parasitos/fisiologia
Águas Residuais
Purificação da Água/métodos
[Mh] Termos MeSH secundário: Compostos de Amônio/análise
Animais
Organismos Aquáticos/microbiologia
Araceae/crescimento & desenvolvimento
Araceae/fisiologia
Biomassa
Daphnia/crescimento & desenvolvimento
Daphnia/microbiologia
Daphnia/fisiologia
Feminino
Nitratos/análise
Nitritos/análise
Oligoquetos/crescimento & desenvolvimento
Oligoquetos/microbiologia
Oligoquetos/fisiologia
Pasteuria/fisiologia
Reprodução
Testes de Toxicidade
Poluentes Químicos da Água/toxicidade
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Ammonium Compounds); 0 (Nitrates); 0 (Nitrites); 0 (Waste Water); 0 (Water Pollutants, Chemical)
[Em] Mês de entrada:1706
[Cu] Atualização por classe:170606
[Lr] Data última revisão:
170606
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170312
[St] Status:MEDLINE


  2 / 55 MEDLINE  
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[PMID]:28266095
[Au] Autor:Clark J; Garbutt JS; McNally L; Little TJ
[Ad] Endereço:Institute of Evolutionary Biology, The University of Edinburgh, Ashworth Laboratories, Kings Buildings, Charlotte Auerbach Road, Edinburgh, EH9 3FL, Scotland.
[Ti] Título:Disease spread in age structured populations with maternal age effects.
[So] Source:Ecol Lett;20(4):445-451, 2017 04.
[Is] ISSN:1461-0248
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Fundamental ecological processes, such as extrinsic mortality, determine population age structure. This influences disease spread when individuals of different ages differ in susceptibility or when maternal age determines offspring susceptibility. We show that Daphnia magna offspring born to young mothers are more susceptible than those born to older mothers, and consider this alongside previous observations that susceptibility declines with age in this system. We used a susceptible-infected compartmental model to investigate how age-specific susceptibility and maternal age effects on offspring susceptibility interact with demographic factors affecting disease spread. Our results show a scenario where an increase in extrinsic mortality drives an increase in transmission potential. Thus, we identify a realistic context in which age effects and maternal effects produce conditions favouring disease transmission.
[Mh] Termos MeSH primário: Envelhecimento
Daphnia/fisiologia
Imunidade Inata
Modelos Biológicos
Pasteuria/fisiologia
[Mh] Termos MeSH secundário: Animais
Daphnia/imunologia
Daphnia/microbiologia
Herança Materna
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171121
[Lr] Data última revisão:
171121
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170308
[St] Status:MEDLINE
[do] DOI:10.1111/ele.12745


  3 / 55 MEDLINE  
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[PMID]:28230237
[Au] Autor:Bourgeois Y; Roulin AC; Müller K; Ebert D
[Ad] Endereço:Zoological Institute, Basel University, Vesalgasse 1, 4051, Basel, Switzerland.
[Ti] Título:Parasitism drives host genome evolution: Insights from the Pasteuria ramosa-Daphnia magna system.
[So] Source:Evolution;71(4):1106-1113, 2017 Apr.
[Is] ISSN:1558-5646
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Because parasitism is thought to play a major role in shaping host genomes, it has been predicted that genomic regions associated with resistance to parasites should stand out in genome scans, revealing signals of selection above the genomic background. To test whether parasitism is indeed such a major factor in host evolution and to better understand host-parasite interaction at the molecular level, we studied genome-wide polymorphisms in 97 genotypes of the planktonic crustacean Daphnia magna originating from three localities across Europe. Daphnia magna is known to coevolve with the bacterial pathogen Pasteuria ramosa for which host genotypes (clonal lines) are either resistant or susceptible. Using association mapping, we identified two genomic regions involved in resistance to P. ramosa, one of which was already known from a previous QTL analysis. We then performed a naïve genome scan to test for signatures of positive selection and found that the two regions identified with the association mapping further stood out as outliers. Several other regions with evidence for selection were also found, but no link between these regions and phenotypic variation could be established. Our results are consistent with the hypothesis that parasitism is driving host genome evolution.
[Mh] Termos MeSH primário: Daphnia/genética
Daphnia/microbiologia
Evolução Molecular
Genoma
Pasteuria/fisiologia
[Mh] Termos MeSH secundário: Animais
Interações Hospedeiro-Patógeno
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170928
[Lr] Data última revisão:
170928
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170224
[St] Status:MEDLINE
[do] DOI:10.1111/evo.13209


  4 / 55 MEDLINE  
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[PMID]:28222092
[Au] Autor:Bento G; Routtu J; Fields PD; Bourgeois Y; Du Pasquier L; Ebert D
[Ad] Endereço:Basel University, Zoological Institute, Vesalgasse 1, Basel, Switzerland.
[Ti] Título:The genetic basis of resistance and matching-allele interactions of a host-parasite system: The Daphnia magna-Pasteuria ramosa model.
[So] Source:PLoS Genet;13(2):e1006596, 2017 Feb.
[Is] ISSN:1553-7404
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Negative frequency-dependent selection (NFDS) is an evolutionary mechanism suggested to govern host-parasite coevolution and the maintenance of genetic diversity at host resistance loci, such as the vertebrate MHC and R-genes in plants. Matching-allele interactions of hosts and parasites that prevent the emergence of host and parasite genotypes that are universally resistant and infective are a genetic mechanism predicted to underpin NFDS. The underlying genetics of matching-allele interactions are unknown even in host-parasite systems with empirical support for coevolution by NFDS, as is the case for the planktonic crustacean Daphnia magna and the bacterial pathogen Pasteuria ramosa. We fine-map one locus associated with D. magna resistance to P. ramosa and genetically characterize two haplotypes of the Pasteuria resistance (PR-) locus using de novo genome and transcriptome sequencing. Sequence comparison of PR-locus haplotypes finds dramatic structural polymorphisms between PR-locus haplotypes including a large portion of each haplotype being composed of non-homologous sequences resulting in haplotypes differing in size by 66 kb. The high divergence of PR-locus haplotypes suggest a history of multiple, diverse and repeated instances of structural mutation events and restricted recombination. Annotation of the haplotypes reveals striking differences in gene content. In particular, a group of glycosyltransferase genes that is present in the susceptible but absent in the resistant haplotype. Moreover, in natural populations, we find that the PR-locus polymorphism is associated with variation in resistance to different P. ramosa genotypes, pointing to the PR-locus polymorphism as being responsible for the matching-allele interactions that have been previously described for this system. Our results conclusively identify a genetic basis for the matching-allele interaction observed in a coevolving host-parasite system and provide a first insight into its molecular basis.
[Mh] Termos MeSH primário: Daphnia/genética
Interações Hospedeiro-Parasita/genética
Pasteuria/genética
Seleção Genética/genética
[Mh] Termos MeSH secundário: Alelos
Animais
Daphnia/microbiologia
Evolução Molecular
Variação Genética
Genótipo
Haplótipos/genética
Pasteuria/patogenicidade
Polimorfismo Genético
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1705
[Cu] Atualização por classe:170526
[Lr] Data última revisão:
170526
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170222
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pgen.1006596


  5 / 55 MEDLINE  
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[PMID]:27862724
[Au] Autor:Joseph S; Schmidt LM; Danquah WB; Timper P; Mekete T
[Ad] Endereço:Entomology and Nematology Department, University of Florida, Gainesville, FL, USA.
[Ti] Título:Genotyping of single spore isolates of a Pasteuria penetrans population occurring in Florida using SNP-based markers.
[So] Source:J Appl Microbiol;122(2):389-401, 2017 Feb.
[Is] ISSN:1365-2672
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:AIMS: To generate single spore lines of a population of bacterial parasite of root-knot nematode (RKN), Pasteuria penetrans, isolated from Florida and examine genotypic variation and virulence characteristics exist within the population. METHODS AND RESULTS: Six single spore lines (SSP), 16SSP, 17SSP, 18SSP, 25SSP, 26SSP and 30SSP were generated. Genetic variability was evaluated by comparing single-nucleotide polymorphisms (SNPs) in six protein-coding genes and the 16S rRNA gene. An average of one SNP was observed for every 69 bp in the 16S rRNA, whereas no SNPs were observed in the protein-coding sequences. Hierarchical cluster analysis of 16S rRNA sequences placed the clones into three distinct clades. Bio-efficacy analysis revealed significant heterogeneity in the level virulence and host specificity between the individual clones. CONCLUSIONS: The SNP markers developed to the 5' hypervariable region of the 16S rRNA gene may be useful in biotype differentiation within a population of P. penetrans. SIGNIFICANCE AND IMPACT OF THE STUDY: This study demonstrates an efficient method for generating single spore lines of P. penetrans and gives a deep insight into genetic heterogeneity and varying level of virulence exists within a population parasitizing a specific Meloidogyne sp. host. The results also suggest that the application of generalist spore lines in nematode management may achieve broad RKN control.
[Mh] Termos MeSH primário: Pasteuria/genética
Pasteuria/isolamento & purificação
Tylenchoidea/microbiologia
[Mh] Termos MeSH secundário: Animais
DNA Bacteriano/genética
Florida
Genótipo
Lycopersicon esculentum
Filogenia
Raízes de Plantas/parasitologia
Polimorfismo de Nucleotídeo Único
RNA Ribossômico 16S
Esporos Bacterianos
Tylenchoidea/genética
Virulência
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (DNA, Bacterial); 0 (RNA, Ribosomal, 16S)
[Em] Mês de entrada:1703
[Cu] Atualização por classe:170817
[Lr] Data última revisão:
170817
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161119
[St] Status:MEDLINE
[do] DOI:10.1111/jam.13345


  6 / 55 MEDLINE  
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[PMID]:27887563
[Au] Autor:Michel J; Ebert D; Hall MD
[Ad] Endereço:University of Basel, Zoological Institute, Vesalgasse 1, 4051, Basel, Switzerland.
[Ti] Título:The trans-generational impact of population density signals on host-parasite interactions.
[So] Source:BMC Evol Biol;16(1):254, 2016 Nov 25.
[Is] ISSN:1471-2148
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: The density of a host population is a key parameter underlying disease transmission, but it also has implications for the expression of disease through its effect on host physiology. In response to higher densities, individuals are predicted to either increase their immune investment in response to the elevated risk of parasitism, or conversely to decrease their immune capacity as a consequence of the stress of a crowded environment. However, an individual's health is shaped by many different factors, including their genetic background, current environmental conditions, and maternal effects. Indeed, population density is often sensed through the presence of info-chemicals in the environment, which may influence a host's interaction with parasites, and also those of its offspring. All of which may alter the expression of disease, and potentially uncouple the presumed link between changes in host density and disease outcomes. RESULTS: In this study, we used the water flea Daphnia magna and its obligate bacterial parasite Pasteuria ramosa, to investigate how signals of high host density impact on host-parasite interactions over two consecutive generations. We found that the chemical signals from crowded treatments induced phenotypic changes in both the parental and offspring generations. In the absence of a pathogen, life-history changes were genotype-specific, but consistent across generations, even when the signal of density was removed. In contrast, the influence of density on infected animals depended on the trait and generation of exposure. When directly exposed to signals of high-density, host genotypes responded differently in how they minimised the severity of disease. Yet, in the subsequent generation, the influence of density was rarely genotype-specific and instead related to ability of the host to minimise the onset of infection. CONCLUSION: Our findings reveal that population level correlations between host density and infection capture only part of the complex relationship between crowding and the severity of disease. We suggest that besides its role in horizontal transmission, signals of density can influence parasite epidemiology by modifying mechanisms of resistance across multiple generations, and elevating variability via genotype-by-environment interactions. Our results help resolve why some studies are able to find a positive correlation between high density and resistance, while others uncover a negative correlation, or even no direct relationship at all.
[Mh] Termos MeSH primário: Daphnia/microbiologia
Interações Hospedeiro-Parasita
Pasteuria/fisiologia
[Mh] Termos MeSH secundário: Animais
Tamanho Corporal
Daphnia/genética
Fertilidade/genética
Genótipo
Análise Multivariada
Parasitos/fisiologia
Pasteuria/genética
Fenótipo
Densidade Demográfica
Análise de Componente Principal
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170809
[Lr] Data última revisão:
170809
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161127
[St] Status:MEDLINE


  7 / 55 MEDLINE  
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[PMID]:27421236
[Au] Autor:Schlotz N; Roulin A; Ebert D; Martin-Creuzburg D
[Ad] Endereço:Limnological Institute, University of Konstanz, Mainaustrasse 252, 78464 Konstanz, Germany. Electronic address: nina.schlotz@uni.kn.
[Ti] Título:Combined effects of dietary polyunsaturated fatty acids and parasite exposure on eicosanoid-related gene expression in an invertebrate model.
[So] Source:Comp Biochem Physiol A Mol Integr Physiol;201:115-123, 2016 Nov.
[Is] ISSN:1531-4332
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Eicosanoids derive from essential polyunsaturated fatty acids (PUFA) and play crucial roles in immunity, development, and reproduction. However, potential links between dietary PUFA supply and eicosanoid biosynthesis are poorly understood, especially in invertebrates. Using Daphnia magna and its bacterial parasite Pasteuria ramosa as model system, we studied the expression of genes coding for key enzymes in eicosanoid biosynthesis and of genes related to oogenesis in response to dietary arachidonic acid and eicosapentaenoic acid in parasite-exposed and non-exposed animals. Gene expression related to cyclooxygenase activity was especially responsive to the dietary PUFA supply and parasite challenge, indicating a role for prostanoid eicosanoids in immunity and reproduction. Vitellogenin gene expression was induced upon parasite exposure in all food treatments, suggesting infection-related interference with the host's reproductive system. Our findings highlight the potential of dietary PUFA to modulate the expression of key enzymes involved in eicosanoid biosynthesis and reproduction and thus underpin the idea that the dietary PUFA supply can influence invertebrate immune functions and host-parasite interactions.
[Mh] Termos MeSH primário: Daphnia/genética
Daphnia/microbiologia
Gorduras Insaturadas na Dieta/administração & dosagem
Eicosanoides/metabolismo
Ácidos Graxos Insaturados/administração & dosagem
Pasteuria/patogenicidade
[Mh] Termos MeSH secundário: Animais
Chlamydomonas/química
Daphnia/fisiologia
Dieta
Feminino
Expressão Gênica
Interações Hospedeiro-Patógeno/genética
Interações Hospedeiro-Patógeno/imunologia
Interações Hospedeiro-Patógeno/fisiologia
Oogênese/genética
Estramenópilas/química
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Dietary Fats, Unsaturated); 0 (Eicosanoids); 0 (Fatty Acids, Unsaturated)
[Em] Mês de entrada:1707
[Cu] Atualização por classe:171008
[Lr] Data última revisão:
171008
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160717
[St] Status:MEDLINE


  8 / 55 MEDLINE  
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[PMID]:27015951
[Au] Autor:Ebert D; Duneau D; Hall MD; Luijckx P; Andras JP; Du Pasquier L; Ben-Ami F
[Ad] Endereço:Zoological Institute, University of Basel, Basel, Switzerland.
[Ti] Título:A Population Biology Perspective on the Stepwise Infection Process of the Bacterial Pathogen Pasteuria ramosa in Daphnia.
[So] Source:Adv Parasitol;91:265-310, 2016.
[Is] ISSN:2163-6079
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:The infection process of many diseases can be divided into series of steps, each one required to successfully complete the parasite's life and transmission cycle. This approach often reveals that the complex phenomenon of infection is composed of a series of more simple mechanisms. Here we demonstrate that a population biology approach, which takes into consideration the natural genetic and environmental variation at each step, can greatly aid our understanding of the evolutionary processes shaping disease traits. We focus in this review on the biology of the bacterial parasite Pasteuria ramosa and its aquatic crustacean host Daphnia, a model system for the evolutionary ecology of infectious disease. Our analysis reveals tremendous differences in the degree to which the environment, host genetics, parasite genetics and their interactions contribute to the expression of disease traits at each of seven different steps. This allows us to predict which steps may respond most readily to selection and which steps are evolutionarily constrained by an absence of variation. We show that the ability of Pasteuria to attach to the host's cuticle (attachment step) stands out as being strongly influenced by the interaction of host and parasite genotypes, but not by environmental factors, making it the prime candidate for coevolutionary interactions. Furthermore, the stepwise approach helps us understanding the evolution of resistance, virulence and host ranges. The population biological approach introduced here is a versatile tool that can be easily transferred to other systems of infectious disease.
[Mh] Termos MeSH primário: Daphnia/microbiologia
Pasteuria/fisiologia
[Mh] Termos MeSH secundário: Animais
Evolução Biológica
Daphnia/genética
Meio Ambiente
Especificidade de Hospedeiro
Interações Hospedeiro-Patógeno
Pasteuria/genética
Pasteuria/patogenicidade
Filogenia
Virulência
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T; REVIEW
[Em] Mês de entrada:1608
[Cu] Atualização por classe:160326
[Lr] Data última revisão:
160326
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160327
[St] Status:MEDLINE


  9 / 55 MEDLINE  
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[PMID]:26763092
[Au] Autor:Metzger CM; Luijckx P; Bento G; Mariadassou M; Ebert D
[Ad] Endereço:Zoological Institute, University of Basel, CH-4051, Basel, Switzerland.
[Ti] Título:The Red Queen lives: Epistasis between linked resistance loci.
[So] Source:Evolution;70(2):480-7, 2016 02.
[Is] ISSN:1558-5646
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:A popular theory explaining the maintenance of genetic recombination (sex) is the Red Queen Theory. This theory revolves around the idea that time-lagged negative frequency-dependent selection by parasites favors rare host genotypes generated through recombination. Although the Red Queen has been studied for decades, one of its key assumptions has remained unsupported. The signature host-parasite specificity underlying the Red Queen, where infection depends on a match between host and parasite genotypes, relies on epistasis between linked resistance loci for which no empirical evidence exists. We performed 13 genetic crosses and tested over 7000 Daphnia magna genotypes for resistance to two strains of the bacterial pathogen Pasteuria ramosa. Results reveal the presence of strong epistasis between three closely linked resistance loci. One locus masks the expression of the other two, while these two interact to produce a single resistance phenotype. Changing a single allele on one of these interacting loci can reverse resistance against the tested parasites. Such a genetic mechanism is consistent with host and parasite specificity assumed by the Red Queen Theory. These results thus provide evidence for a fundamental assumption of this theory and provide a genetic basis for understanding the Red Queen dynamics in the Daphnia-Pasteuria system.
[Mh] Termos MeSH primário: Resistência à Doença/genética
Epistasia Genética
Ligação Genética
Loci Gênicos
Interações Hospedeiro-Patógeno/genética
Modelos Genéticos
[Mh] Termos MeSH secundário: Animais
Daphnia/genética
Daphnia/imunologia
Daphnia/microbiologia
Pasteuria/genética
Pasteuria/patogenicidade
Fenótipo
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Em] Mês de entrada:1611
[Cu] Atualização por classe:170504
[Lr] Data última revisão:
170504
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160115
[St] Status:MEDLINE
[do] DOI:10.1111/evo.12854


  10 / 55 MEDLINE  
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[PMID]:26709232
[Au] Autor:Duneau D; Ebert D; Du Pasquier L
[Ad] Endereço:University of Basel, Zoological Institute, Vesalgasse 1, Basel, Switzerland. Electronic address: david.duneau@univ-tlse3.fr.
[Ti] Título:Infections by Pasteuria do not protect its natural host Daphnia magna from subsequent infections.
[So] Source:Dev Comp Immunol;57:120-5, 2016 Apr.
[Is] ISSN:1879-0089
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:The existence of immunological memory in invertebrates remains a contentious topic. Exposure of Daphnia magna crustaceans to a noninfectious dose of the bacterium Pasteuria ramosa has been reported to reduce the chance of future infection upon exposure to higher doses. Using clonal hosts and parasites, we tested whether initial exposure of the host to the parasite (priming), followed by clearing of the parasite with antibiotic, protects the host from a second exposure (challenge). Our experiments included three treatments: priming and challenge with the same or with a different parasite clone, or no priming. Two independent experiments showed that both the likelihood of infection and the degree of parasite proliferation did not differ between treatments, supporting the conclusion that there is no immunological memory in this system. We discuss the possibility that previous discordant reports could result from immune or stress responses that did not fade following initial priming.
[Mh] Termos MeSH primário: Daphnia/imunologia
Infecções por Bactérias Gram-Positivas/imunologia
Memória Imunológica
Pasteuria/imunologia
[Mh] Termos MeSH secundário: Animais
Antibacterianos/uso terapêutico
Infecções por Bactérias Gram-Positivas/tratamento farmacológico
Interações Hospedeiro-Patógeno
Imunidade Inata
Recidiva
Vacinação
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Anti-Bacterial Agents)
[Em] Mês de entrada:1610
[Cu] Atualização por classe:161230
[Lr] Data última revisão:
161230
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:151229
[St] Status:MEDLINE



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